Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT1MPAY)

• DTT Name: GABA(A) receptor alpha-1 (GABRA1) DTT Info
• Gene Name: GABRA1

Molecule-Related Drug & Molecule List

25 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Allopregnanolone	DMNLHAC	Depression	6A70-6A7Z	approved	[1]
Amobarbital	DM0GQ8N	Epilepsy	8A60-8A68	Approved	[2]
Barbital	DMJ8NMC	Insomnia	7A00-7A0Z	Approved	[2]
Barbiturate	DMJIA6T	Anaesthesia	9A78.6	Approved	[2]
Butabarbital	DMC5AST	Dysuria	MF50.7	Approved	[2]
Butalbital	DM9J04X	Anxiety disorder	6B00-6B0Z	Approved	[2]
Butethal	DM7JHX0	Insomnia	7A00-7A0Z	Approved	[2]
Clobazam - Lundbeck	DMW1OQ0	Anxiety disorder	6B00-6B0Z	Approved	[2]
Ethanol	DMDRQZU	Chronic pain	MG30	Approved	[2]
Ethchlorvynol	DM53IP1	Insomnia	7A00-7A0Z	Approved	[2]
Hexobarbital	DMQ314B	Anaesthesia	9A78.6	Approved	[2]
Indiplon	DMOPGHQ	Fibromyalgia	MG30.01	Approved	[3]
Meprobamate	DMHM93Y	Anxiety		Approved	[2]
Methohexital	DM7YMIT	Anaesthesia	9A78.6	Approved	[2]
Methoxyflurane	DML0RAE	Anaesthesia	9A78.6	Approved	[2]
Methylphenobarbital	DMDSWAG	Anxiety		Approved	[2]
Methyprylon	DMBW7VH	Insomnia	7A00-7A0Z	Approved	[2]
Nitrazepam	DMEGIQ6	Epilepsy	8A60-8A68	Approved	[2]
Pentobarbital	DMFNH7L	Brain ischaemia	8B1Z	Approved	[2]
Picrotoxin	DMIBNG2	Respiratory distress syndrome	CB00	Approved	[2]
Primidone	DM0WX6I	Epilepsy	8A60-8A68	Approved	[2]
Secobarbital	DM14RF5	Epilepsy	8A60-8A68	Approved	[2]
THIOCOLCHICOSIDE	DMEPWYA	Muscle spasm	MB47.3	Approved	[4]
Zaleplon	DMGFWSM	Insomnia	7A00-7A0Z	Approved	[5]
Zolpidem	DMWOSKJ	Insomnia	7A00-7A0Z	Approved	[6]

3 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ZK-93423	DMFWMKZ	Epileptic seizures	8A61-8A6Z	Phase 3	[7]
EVT-201	DMQGBM1	Insomnia	7A00-7A0Z	Phase 2	[8]
GSK683699	DMTW79H	Inflammatory bowel disease	DD72	Phase 2	[4]

4 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ELTANOLONE	DM38CIV	Premenstrual syndrome	GA34.40	Discontinued in Phase 3	[1]
U-78875	DM2WOPX	Anxiety disorder	6B00-6B0Z	Discontinued in Phase 1	[9]
CGS-9896	DM39PQI	N. A.	N. A.	Terminated	[10]
Divaplon	DMO3XBP	N. A.	N. A.	Terminated	[11]

161 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
(2-Amino-4,5-dihydro-thiazol-4-yl)-acetic acid	DMLEZKJ	Discovery agent	N.A.	Investigative	[12]
(2E,4S)-4-ammoniopent-2-enoate	DMA9RIS	Discovery agent	N.A.	Investigative	[13]
(4R)-4-ammoniopentanoate	DMZFTI4	Discovery agent	N.A.	Investigative	[13]
(4S)-4-ammoniopentanoate	DMBLAY1	Discovery agent	N.A.	Investigative	[13]
(6-Benzylamino-9H-beta-carbolin-3-yl)-methanol	DMAXS9H	Discovery agent	N.A.	Investigative	[14]
(9-Benzyl-9H-purin-6-yl)-cyclopropyl-amine	DMHJG5N	Discovery agent	N.A.	Investigative	[15]
(9H-beta-Carbolin-3-yl)-carbamic acid ethyl ester	DMKI2Y9	Discovery agent	N.A.	Investigative	[16]
(9H-beta-Carbolin-3-yl)-ethyl-amine	DMVHMPC	Discovery agent	N.A.	Investigative	[16]
(9H-beta-Carbolin-3-yl)-methanol	DMUF16A	Discovery agent	N.A.	Investigative	[14]
(beta-CCE)9H-beta-Carboline-3-carboxylic acid	DMVWQ26	Discovery agent	N.A.	Investigative	[17]
1,1-Dimethyl-5-oxa-spiro[2.4]heptan-4-one	DMOGHRS	Discovery agent	N.A.	Investigative	[18]
1,3-Diphenyl-1H-chromeno[4,3-c]pyrazol-4-one	DM1KND6	Discovery agent	N.A.	Investigative	[19]
1-(4-chlorophenyl)-4-phenyl-1H-imidazole	DMVCHSI	Discovery agent	N.A.	Investigative	[10]
1-(9H-beta-Carbolin-3-yl)-butan-1-one	DMA96U5	Discovery agent	N.A.	Investigative	[20]
1-(9H-beta-Carbolin-3-yl)-ethanone	DMFOD2L	Discovery agent	N.A.	Investigative	[14]
1-Methyl-5-oxa-spiro[2.4]heptan-4-one	DMX2FWN	Discovery agent	N.A.	Investigative	[18]
2-(1H-Indol-3-yl)-2-oxo-N-phenethyl-acetamide	DMFAME4	Discovery agent	N.A.	Investigative	[17]
2-(3-Bromo-phenyl)-6-nitro-chromen-4-one	DM9RAYC	Discovery agent	N.A.	Investigative	[21]
2-(3-Bromo-phenyl)-chromen-4-one	DM7XDLO	Discovery agent	N.A.	Investigative	[21]
2-(3-Chloro-phenyl)-chromen-4-one	DML83DM	Discovery agent	N.A.	Investigative	[21]
2-(4-Chloro-phenyl)-3H-imidazo[4,5-c]quinoline	DMSB0JA	Discovery agent	N.A.	Investigative	[22]
2-(4-chlorophenyl)-5-phenyl-4-isoxazolin-3-one	DMYGRS9	Discovery agent	N.A.	Investigative	[10]
2-(9-Benzyl-9H-purin-6-ylamino)-ethanol	DMPJ0O6	Discovery agent	N.A.	Investigative	[15]
2-Furan-2-yl-6H-pyrazolo[1,5-c]quinazolin-5-one	DMHT80R	Discovery agent	N.A.	Investigative	[23]
2-Isoxazol-3-yl-3H-imidazo[4,5-c]quinoline	DM1F4TN	Discovery agent	N.A.	Investigative	[22]
2-Isoxazol-5-yl-3H-imidazo[4,5-c]quinoline	DMD2ZNA	Discovery agent	N.A.	Investigative	[22]
2-Oxa-spiro[4.4]nonan-1-one	DM2NEX4	Discovery agent	N.A.	Investigative	[18]
2-p-Tolyl-6H-pyrazolo[1,5-c]quinazolin-5-one	DMJIVL3	Discovery agent	N.A.	Investigative	[23]
2-Phenyl-3H-imidazo[4,5-c]quinoline	DML9DJP	Discovery agent	N.A.	Investigative	[22]
2-Phenyl-5,6-dihydro-pyrazolo[1,5-c]quinazoline	DMUIYZB	Discovery agent	N.A.	Investigative	[23]
2-Phenyl-6H-pyrazolo[1,5-c]quinazolin-5-one	DMA1RHE	Discovery agent	N.A.	Investigative	[23]
2-Pyridin-2-yl-6H-pyrazolo[1,5-c]quinazolin-5-one	DMLCDZN	Discovery agent	N.A.	Investigative	[23]
2-Thiophen-2-yl-3H-imidazo[4,5-c]quinoline	DMPF598	Discovery agent	N.A.	Investigative	[22]
3,3-Diethyl-dihydro-furan-2-one	DMFJ9N0	Discovery agent	N.A.	Investigative	[18]
3,3-Diisopropyl-dihydro-furan-2-one	DMIFUDG	Discovery agent	N.A.	Investigative	[18]
3-(2,2-Dimethyl-propoxy)-9H-beta-carboline	DMSCIP2	Discovery agent	N.A.	Investigative	[20]
3-(3-Methyl-butoxy)-9H-beta-carboline	DMTNCXP	Discovery agent	N.A.	Investigative	[20]
3-(benzyloxy)-9H-pyrido[3,4-b]indole	DMDNEKR	Discovery agent	N.A.	Investigative	[24]
3-(hexa-1,3-dienyloxy)-9H-pyrido[3,4-b]indole	DMKHNTY	Discovery agent	N.A.	Investigative	[24]
3-amino-3-demethoxythiocolchicine	DM60K7H	Discovery agent	N.A.	Investigative	[4]
3-Butoxy-9H-beta-carboline	DMQ8H74	Discovery agent	N.A.	Investigative	[20]
3-butoxycarbonyl-4-quinolone	DMRF2Q8	Discovery agent	N.A.	Investigative	[25]
3-butoxycarbonyl-6-ethyl-4-quinolone	DMD6PMZ	Discovery agent	N.A.	Investigative	[25]
3-butylaminocarbonyl-6-ethyl-4-quinolone	DM95XWR	Discovery agent	N.A.	Investigative	[25]
3-carboxy-6-ethyl-4-quinolone	DMRUX93	Discovery agent	N.A.	Investigative	[25]
3-Chloro-9H-beta-carboline	DMCD901	Discovery agent	N.A.	Investigative	[26]
3-cyclopentoxycarbonyl-6-ethyl-4-quinolone	DMEL8S5	Discovery agent	N.A.	Investigative	[25]
3-demethoxy-3-D-lyxopyranosylaminothiocolchicine	DME8VPC	Discovery agent	N.A.	Investigative	[4]
3-demethoxy-3-D-mannopyranosylaminothiocolchicine	DMALMGH	Discovery agent	N.A.	Investigative	[4]
3-demethoxy-3-D-xylopyranosylaminothiocolchicine	DMXFVD1	Discovery agent	N.A.	Investigative	[4]
3-demethoxy-3-L-fucopyranosylaminothiocolchicine	DM4ERYF	Discovery agent	N.A.	Investigative	[4]
3-demethoxy-3D-glucopyranosylaminothiocolchicine	DMID7TC	Discovery agent	N.A.	Investigative	[4]
3-Ethoxy-9H-beta-carboline	DM6K7BI	Discovery agent	N.A.	Investigative	[26]
3-ethoxycarbonyl-4-quinolone	DMY4VOI	Discovery agent	N.A.	Investigative	[25]
3-ethoxycarbonyl-6-ethyl-2-methyl-4-quinolone	DMMDOI4	Discovery agent	N.A.	Investigative	[25]
3-ethoxycarbonyl-6-propyl-4-quinolone	DM1E5QZ	Discovery agent	N.A.	Investigative	[25]
3-Ethyl-3-isopropyl-dihydro-furan-2-one	DMZK13I	Discovery agent	N.A.	Investigative	[18]
3-Ethyl-3-methyl-dihydro-furan-2-one	DM1VTFU	Discovery agent	N.A.	Investigative	[18]
3-Isobutoxy-9H-beta-carboline	DM6X5TZ	Discovery agent	N.A.	Investigative	[20]
3-Isopropoxy-9H-beta-carboline	DM7PHO4	Discovery agent	N.A.	Investigative	[20]
3-Isopropyl-3-methyl-dihydro-furan-2-one	DMSLPGZ	Discovery agent	N.A.	Investigative	[18]
3-Isothiocyanato-9H-beta-carboline	DM9LEWH	Discovery agent	N.A.	Investigative	[27]
3-Methoxy-9H-beta-carboline	DMTBX0D	Discovery agent	N.A.	Investigative	[26]
3-Methoxycarbonyl-2-methyl-9H-beta-carbolin-2-ium	DMQMT1A	Discovery agent	N.A.	Investigative	[28]
3-Methyl-1-phenyl-1H-chromeno[4,3-c]pyrazol-4-one	DMTM6B0	Discovery agent	N.A.	Investigative	[19]
3-Methyl-2-phenyl-2H-chromeno[4,3-c]pyrazol-4-one	DM870UV	Discovery agent	N.A.	Investigative	[19]
3-Methyl-9H-beta-carboline	DMEJKZN	Discovery agent	N.A.	Investigative	[29]
3-Nitro-9H-beta-carboline	DM08V9W	Discovery agent	N.A.	Investigative	[26]
3-Propoxy-9H-beta-carboline	DMDEV64	Discovery agent	N.A.	Investigative	[26]
3-sec-Butoxy-9H-beta-carboline	DMNP8DQ	Discovery agent	N.A.	Investigative	[20]
3-tert-Butyl-3-ethyl-dihydro-furan-2-one	DMGDT8V	Discovery agent	N.A.	Investigative	[18]
4-(2-aminoethyl)-1,2,5-oxadiazol-3-ol	DMCS538	Discovery agent	N.A.	Investigative	[30]
4-(4-chlorophenyl)-1-pyrid-2-yl-pyrazole	DMJI6QH	Discovery agent	N.A.	Investigative	[10]
4-(biphenyl-3-yl)-5-(piperidin-4-yl)isoxazol-3-ol	DM1T95Y	Discovery agent	N.A.	Investigative	[31]
4-benzyl-5-(4-piperidyl)isothiazol-3-ol	DMZ18OJ	Discovery agent	N.A.	Investigative	[32]
4-Benzyl-5-piperidin-4-yl-isoxazol-3-ol	DMA4CZK	Discovery agent	N.A.	Investigative	[33]
4-Methoxymethyl-3,6-dipropoxy-9H-beta-carboline	DMCS83F	Discovery agent	N.A.	Investigative	[34]
4-Methyl-5-(4-piperidyl)isothiazol-3-ol	DMV19HC	Discovery agent	N.A.	Investigative	[32]
4-Naphthalen-1-yl-5-piperidin-4-yl-isoxazol-3-ol	DMEIA3L	Discovery agent	N.A.	Investigative	[33]
4-Naphthalen-2-yl-5-piperidin-4-yl-isoxazol-3-ol	DM9O8UM	Discovery agent	N.A.	Investigative	[33]
4-Phenyl-5-piperidin-4-yl-isoxazol-3-ol	DM7E4JU	Discovery agent	N.A.	Investigative	[33]
5-(4-piperidyl)-4-propylisothiazol-3-ol	DMZ7K5G	Discovery agent	N.A.	Investigative	[32]
5-(piperidin-4-yl)isothiazol-3-ol	DM4XGFW	Discovery agent	N.A.	Investigative	[32]
5-(piperidin-4-yl)isoxazol-3-ol	DM6GO2I	Discovery agent	N.A.	Investigative	[33]
5-[(1R)-1-ammonioethyl]isoxazol-3-olate	DM23PL4	Discovery agent	N.A.	Investigative	[13]
5-[(1S)-1-ammonioethyl]isoxazol-3-olate	DMYAPLT	Discovery agent	N.A.	Investigative	[13]
6,6-Dimethyl-2-oxa-spiro[4.4]nonan-1-one	DMOIFAP	Discovery agent	N.A.	Investigative	[18]
6,9-Dimethyl-2-oxa-spiro[4.4]nonan-1-one	DM7FMWS	Discovery agent	N.A.	Investigative	[18]
6-benzyl-3-ethoxycarbonyl-4-quinolone	DMICRFQ	Discovery agent	N.A.	Investigative	[25]
6-benzyl-3-propoxycarbonyl-4-quinolone	DMXMI5E	Discovery agent	N.A.	Investigative	[25]
6-benzyl-3-propylaminocarbonyl-4-quinolone	DM7HNPJ	Discovery agent	N.A.	Investigative	[25]
6-Bromo-2-(2-nitro-phenyl)-chromen-4-one	DM7U58O	Discovery agent	N.A.	Investigative	[35]
6-Bromo-2-(3-bromo-phenyl)-chromen-4-one	DMTJRF3	Discovery agent	N.A.	Investigative	[21]
6-Bromo-2-(3-nitro-phenyl)-chromen-4-one	DMP8ZVS	Discovery agent	N.A.	Investigative	[35]
6-Bromo-2-(4-nitro-phenyl)-chromen-4-one	DMCX3TM	Discovery agent	N.A.	Investigative	[35]
6-Bromo-2-phenyl-chromen-4-one	DMMCNQI	Discovery agent	N.A.	Investigative	[21]
6-bromo-3-ethoxycarbonyl-2-methyl-4-quinolone	DM4HRIX	Discovery agent	N.A.	Investigative	[25]
6-bromo-3-ethoxycarbonyl-4-quinolone	DM0MQHP	Discovery agent	N.A.	Investigative	[25]
6-Chloro-2-(3-nitro-phenyl)-chromen-4-one	DMTWBOV	Discovery agent	N.A.	Investigative	[21]
6-Chloro-2-phenyl-chromen-4-one	DM5FZDI	Discovery agent	N.A.	Investigative	[21]
6-ethyl-3-(2-ethylbutoxycarbonyl)-4-quinolone	DMLEUP2	Discovery agent	N.A.	Investigative	[25]
6-ethyl-3-(2-methylbutoxycarbonyl)-4-quinolone	DMESU53	Discovery agent	N.A.	Investigative	[25]
6-ethyl-3-(3-methylbutoxycarbonyl)-4-quinolone	DM1POEA	Discovery agent	N.A.	Investigative	[25]
6-ethyl-3-(3-pentoxycarbonyl)-4-quinolone	DMG05V1	Discovery agent	N.A.	Investigative	[25]
6-ethyl-3-i-propoxycarbonyl-4-quinolone	DML9EU7	Discovery agent	N.A.	Investigative	[25]
6-ethyl-3-pentoxycarbonyl-4-quinolone	DMSGJM6	Discovery agent	N.A.	Investigative	[25]
6-ethyl-3-propoxycarbonyl-4-quinolone	DMGVI08	Discovery agent	N.A.	Investigative	[25]
6-ethyl-3-propylaminocarbonyl-4-quinolone	DMC1F2E	Discovery agent	N.A.	Investigative	[25]
6-Fluoro-2-(3-nitro-phenyl)-chromen-4-one	DMPZIV0	Discovery agent	N.A.	Investigative	[21]
6-Methyl-2-oxa-spiro[4.4]nonan-1-one	DMNJRFP	Discovery agent	N.A.	Investigative	[18]
6-Nitro-2-(3-nitro-phenyl)-chromen-4-one	DMRCTBA	Discovery agent	N.A.	Investigative	[36]
6-Nitro-2-(4-nitro-phenyl)-chromen-4-one	DMM635K	Discovery agent	N.A.	Investigative	[36]
6-Nitro-2-phenyl-chromen-4-one	DMVLID9	Discovery agent	N.A.	Investigative	[21]
7,12-Dihydro-5,7,12-triaza-indeno[1,2-a]fluorene	DM3FXRC	Discovery agent	N.A.	Investigative	[37]
7,12-Dihydro-7,12-diaza-indeno[1,2-a]fluorene	DMTZ943	Discovery agent	N.A.	Investigative	[26]
9H-beta-Carbolin-3-ol	DMBWAMR	Discovery agent	N.A.	Investigative	[26]
9H-beta-Carbolin-6-ylamine	DMBLEI7	Discovery agent	N.A.	Investigative	[14]
9H-beta-Carboline-3-carboxylic acid ethyl ester	DMK459I	Discovery agent	N.A.	Investigative	[24]
9H-beta-Carboline-3-carboxylic acid propyl ester	DMMUH98	Discovery agent	N.A.	Investigative	[38]
AMENTOFLAVONE	DMLRNV2	Discovery agent	N.A.	Investigative	[39]
Barbituric acid derivative	DM2I19P	Discovery agent	N.A.	Investigative	[40]
Benzyl-(9H-beta-carbolin-6-yl)-amine	DMW167A	Discovery agent	N.A.	Investigative	[26]
Beta-Carboline-3-carboxylic acid t-butyl ester	DM9LT60	N. A.	N. A.	Investigative	[24]
BETA-CCM	DM1MFTZ	Discovery agent	N.A.	Investigative	[41]
CGS-13767	DM4DSE7	Discovery agent	N.A.	Investigative	[42]
CGS-9895	DMKY6CU	Discovery agent	N.A.	Investigative	[43]
CI-218872	DM0RH3S	Discovery agent	N.A.	Investigative	[29]
Ethyl 6-iodo-9H-pyrido[3,4-b]indole-3-carboxylate	DM5G91Z	Discovery agent	N.A.	Investigative	[24]
flavone	DMEQH6J	Discovery agent	N.A.	Investigative	[21]
GNF-PF-3645	DM17GIV	Discovery agent	N.A.	Investigative	[25]
GNF-PF-4421	DMV10UH	Discovery agent	N.A.	Investigative	[25]
Isoquinoline-3-carboxylic acid methyl ester	DMWIMUZ	Discovery agent	N.A.	Investigative	[26]
L-655708	DM4CDIB	Discovery agent	N.A.	Investigative	[44]
N-(9H-beta-Carbolin-3-yl)-acetamide	DMBD52I	Discovery agent	N.A.	Investigative	[16]
N-(9H-beta-Carbolin-3-yl)-formamide	DM3KNSY	Discovery agent	N.A.	Investigative	[16]
N-(p-methylbenzyl)-5-nitroindol-3-ylglyoxylamide	DMULBO9	Discovery agent	N.A.	Investigative	[45]
N-Benzyl-2-(1H-indol-3-yl)-2-oxo-acetamide	DM8A23B	Discovery agent	N.A.	Investigative	[45]
N-benzyl-2-(5-nitro-1H-indol-3-yl)-2-oxoacetamide	DMMT65J	Discovery agent	N.A.	Investigative	[45]
N-butyl-2-(1H-indol-3-yl)-2-oxoacetamide	DM157LQ	Discovery agent	N.A.	Investigative	[45]
N-butyl-2-(5-nitro-1H-indol-3-yl)-2-oxoacetamide	DMH7Z4L	Discovery agent	N.A.	Investigative	[45]
N-Indan-1-yl-2-(1H-indol-3-yl)-2-oxo-acetamide	DM8ZMB5	Discovery agent	N.A.	Investigative	[46]
NORHARMANE	DMKYQWG	Discovery agent	N.A.	Investigative	[26]
NSC-73613	DMT6CV5	Discovery agent	N.A.	Investigative	[21]
NSC-93394	DM2JPD4	Discovery agent	N.A.	Investigative	[21]
Pyrrolidin-3-yl-acetic acid	DM0BHCJ	Discovery agent	N.A.	Investigative	[47]
Ridine-5-carboxylic acid ethyl ester	DM9HMCS	Discovery agent	N.A.	Investigative	[48]
RIPAZEPAM	DMTHVQD	Discovery agent	N.A.	Investigative	[49]
RO-054520	DM78B4A	Discovery agent	N.A.	Investigative	[50]
RO-145974	DM0ACKJ	Discovery agent	N.A.	Investigative	[51]
RO-145975	DMAJ6BW	Discovery agent	N.A.	Investigative	[51]
RO-147437	DMX4B36	Discovery agent	N.A.	Investigative	[51]
Ro-15-3505	DM4NW3U	Discovery agent	N.A.	Investigative	[51]
RO-194603	DM8C2Z0	Discovery agent	N.A.	Investigative	[51]
Ro-4938581	DMCB2N9	Discovery agent	N.A.	Investigative	[52]
RWJ-16979	DME68VT	Discovery agent	N.A.	Investigative	[53]
RY-066	DMGUX16	Discovery agent	N.A.	Investigative	[54]
Sec-butyl 9H-pyrido[3,4-b]indole-3-carboxylate	DM9QSDC	Discovery agent	N.A.	Investigative	[24]
U-89267	DMQT6AH	Discovery agent	N.A.	Investigative	[55]
[3H]CGP27492	DMQTBRM	Discovery agent	N.A.	Investigative	[56]
[3H]CGS8216	DMLP68J	Inflammation	1A00-CA43.1	Investigative	[42]
[3H]Ro154513	DMMBWKL	Discovery agent	N.A.	Investigative	[51]

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