Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM9B6Y1)

Drug Name
NORCANTHARIDIN Drug Info
Synonyms
Norcantharidin; 5442/12/6; Endothall anhydride; Norcantharadine; 7-Oxabicyclo[221]heptane-2,3-dicarboxylic anhydride; 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-; 3,6-Endoxohexahydrophthalic anhydride; 29745-04-8; Hexahydro-4,7-epoxyisobenzofuran-1,3-dione; NSC 14003; 7-Oxabicyclo(221)heptane-2,3-dicarboxylic anhydride; FR-0742; 3,6-Endooxyphthalic anhydride, hexahydro-; Phthalic anhydride, hexahydro-3,6-endoxo-; C8H8O4; 4,10-dioxatricyclo[5210< 2,6> ]decane-3,5-dione; NSC 59023; BRN 0084287; DEMETHYL-CANTHARIDIN
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
93004
ChEBI ID
CHEMBL8327
CAS Number
CAS 5442-12-6
TTD Drug ID
DM9B6Y1

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Investigative Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting Serine/threonine PP1-alpha (PPP1CA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cantharidin DMBP5N3 Molluscum contagiosum infection 1E76 Approved [6]
PALASONIN DMDTP1R Discovery agent N.A. Investigative [6]
TAUTOMYCIN DMC92DQ Discovery agent N.A. Investigative [6]
CANTHARIDIC_ACID DME32XU Discovery agent N.A. Investigative [6]
MICROCYSTIN-LR DMTMLRN Discovery agent N.A. Investigative [6]
Drug(s) Affected By Serine/threonine-protein kinase Chk1 (CHEK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [7]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [8]
Methotrexate DM2TEOL Anterior urethra cancer Approved [9]
Quercetin DM3NC4M Obesity 5B81 Approved [10]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [11]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [12]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [13]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [14]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [15]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [16]
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Drug(s) Affected By Bcl-2-like protein 11 (BCL2L11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [17]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [18]
Quercetin DM3NC4M Obesity 5B81 Approved [19]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [20]
Remdesivir DMBFZ6L Coronavirus Disease 2019 (COVID-19) 1D6Y Approved [21]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [22]
Panobinostat DM58WKG Chronic graft versus host disease Approved [23]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [24]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [25]
Testosterone DM7HUNW Hot flushes GA30 Approved [26]
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Drug(s) Affected By Serine/threonine-protein kinase/endoribonuclease IRE1 (ERN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [27]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [28]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [29]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [30]
Quercetin DM3NC4M Obesity 5B81 Approved [31]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [30]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [33]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [34]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [30]
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Drug(s) Affected By Serine/threonine-protein kinase Chk2 (CHEK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [35]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [7]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [36]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [14]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [37]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [38]
Testosterone DM7HUNW Hot flushes GA30 Approved [39]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [39]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Capsaicin DMGMF6V Back pain ME84.Z Approved [41]
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Drug(s) Affected By Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [28]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [42]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [43]
Quercetin DM3NC4M Obesity 5B81 Approved [44]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [45]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [46]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [47]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [33]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [48]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [49]
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Drug(s) Affected By Poly polymerase 1 (PARP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [50]
Gefitinib DM15F0X Colon adenocarcinoma Approved [51]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [52]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [53]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [54]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [55]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [54]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [56]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [57]
Methotrexate DM2TEOL Anterior urethra cancer Approved [58]
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Drug(s) Affected By Metalloproteinase inhibitor 2 (TIMP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [59]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [60]
Selenium DM25CGV N. A. N. A. Approved [61]
Quercetin DM3NC4M Obesity 5B81 Approved [62]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [63]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [64]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [65]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [66]
Tetracaine DM9J6C2 Spinal anesthesia MB40.3 Approved [67]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [68]
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Drug(s) Affected By Histone H2AX (H2AX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [69]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [70]
Selenium DM25CGV N. A. N. A. Approved [71]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [72]
Etretinate DM2CZFA Keratosis ED56 Approved [73]
Methotrexate DM2TEOL Anterior urethra cancer Approved [74]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [75]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [76]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [77]
Quercetin DM3NC4M Obesity 5B81 Approved [78]
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Drug(s) Affected By Cyclic AMP-dependent transcription factor ATF-4 (ATF4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [28]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [79]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [80]
Selenium DM25CGV N. A. N. A. Approved [71]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [81]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [33]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [34]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [82]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [83]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [84]
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Drug(s) Affected By Tumor necrosis factor receptor superfamily member 6 (FAS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [85]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [8]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [53]
Methotrexate DM2TEOL Anterior urethra cancer Approved [86]
Epinephrine DM3KJBC Acute asthma CA23 Approved [87]
Quercetin DM3NC4M Obesity 5B81 Approved [88]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [89]
Fructose DM43AN2 Vomiting MD90 Approved [90]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [85]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [91]
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Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [92]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [93]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [94]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [95]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [96]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [97]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [98]
Gefitinib DM15F0X Colon adenocarcinoma Approved [99]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [100]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [101]
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Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [102]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [93]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [103]
Paclitaxel DMLB81S Breast carcinoma Approved [104]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [105]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [92]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [106]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [107]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [95]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [96]
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Drug(s) Affected By M-phase inducer phosphatase 3 (CDC25C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [7]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [80]
Methotrexate DM2TEOL Anterior urethra cancer Approved [108]
Quercetin DM3NC4M Obesity 5B81 Approved [44]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [12]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [20]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [109]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [110]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [111]
Testosterone DM7HUNW Hot flushes GA30 Approved [39]
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Drug(s) Affected By DNA damage-inducible transcript 3 protein (DDIT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [112]
Triacetin DM0AEPG Onychomycosis EE12.1 Approved [113]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [28]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [79]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [30]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [8]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [114]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [115]
Methotrexate DM2TEOL Anterior urethra cancer Approved [116]
Quercetin DM3NC4M Obesity 5B81 Approved [44]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [117]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [118]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [119]
Gefitinib DM15F0X Colon adenocarcinoma Approved [120]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [121]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [8]
Etretinate DM2CZFA Keratosis ED56 Approved [122]
Prednisone DM2HG4X Acute asthma CA23 Approved [123]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [55]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [124]
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Drug(s) Affected By Mitogen-activated protein kinase 8 (MAPK8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [125]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [126]
Gefitinib DM15F0X Colon adenocarcinoma Approved [127]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [128]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [129]
Quercetin DM3NC4M Obesity 5B81 Approved [10]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [48]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [130]
Vinblastine DM5TVS3 Advanced cancer 2A00-2F9Z Approved [129]
Ethacrynic acid DM60QMR Edema MG29 Approved [131]
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Drug(s) Affected By Mitogen-activated protein kinase 9 (MAPK9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [126]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [80]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [129]
Methotrexate DM2TEOL Anterior urethra cancer Approved [132]
Quercetin DM3NC4M Obesity 5B81 Approved [133]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [20]
Vinblastine DM5TVS3 Advanced cancer 2A00-2F9Z Approved [129]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [134]
Sorbitol DMAN0DE Constipation DD91.1 Approved [135]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [136]
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Drug(s) Affected By Signal transducer and activator of transcription 5B (STAT5B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [137]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [138]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [139]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [65]
Quizartinib DM8Y4JS Acute myeloid leukaemia 2A60 Approved [140]
Tofacitinib DMBS370 Rheumatoid arthritis FA20 Approved [141]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [142]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [143]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [144]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [145]
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Drug(s) Affected By BH3-interacting domain death agonist (BID)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [107]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [53]
Selenium DM25CGV N. A. N. A. Approved [146]
Quercetin DM3NC4M Obesity 5B81 Approved [10]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [147]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [148]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [149]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [150]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [136]
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Drug(s) Affected By Bcl-2-like protein 1 (BCL2L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [151]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [152]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [53]
Selenium DM25CGV N. A. N. A. Approved [71]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [153]
Methotrexate DM2TEOL Anterior urethra cancer Approved [108]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [154]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [155]
Quercetin DM3NC4M Obesity 5B81 Approved [10]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [156]
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Drug(s) Affected By Bcl-2 homologous antagonist/killer (BAK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [157]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [80]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [158]
Methotrexate DM2TEOL Anterior urethra cancer Approved [108]
Quercetin DM3NC4M Obesity 5B81 Approved [159]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Levamisole DM5EN79 Parasitic infection 1D0Y-1G2Z Approved [160]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [161]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [162]
Promethazine DM6I5GR Hyperemesis gravidarum Approved [163]
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Drug(s) Affected By NAD-dependent protein deacylase sirtuin-6 (SIRT6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [164]
Testosterone DM7HUNW Hot flushes GA30 Approved [26]
Hesperetin DMKER83 High blood cholesterol level 5C80.00 Approved [165]
Paclitaxel DMLB81S Breast carcinoma Approved [5]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [166]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [167]
SEN-196 DMLDBQ5 Huntington disease 8A01.10 Phase 2 [168]
TAK-715 DMZKPI8 Rheumatoid arthritis FA20 Phase 2 [169]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [170]
paraquat DMR8O3X Discovery agent N.A. Investigative [171]
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Drug(s) Affected By Bcl2-associated agonist of cell death (BAD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paclitaxel DMLB81S Breast carcinoma Approved [172]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [173]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [107]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [174]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [175]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [147]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [177]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [24]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [38]
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Drug(s) Affected By NAD-dependent protein deacetylase sirtuin-7 (SIRT7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [44]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [178]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Paclitaxel DMLB81S Breast carcinoma Approved [5]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [166]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [179]
Curcumin DMQPH29 Solid tumour/cancer 2A00-2F9Z Phase 3 [180]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [170]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [181]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [182]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
PP2A B subunit isoform R5-alpha (PPP2R5A) TTLONKX 2A5A_HUMAN Inhibitor [2]
Serine/threonine PP1-alpha (PPP1CA) TTFLH0E PP1A_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Bcl-2 homologous antagonist/killer (BAK1) OTDP6ILW BAK_HUMAN Gene/Protein Processing [3]
Bcl-2-like protein 1 (BCL2L1) OTRC5K9O B2CL1_HUMAN Gene/Protein Processing [4]
Bcl-2-like protein 11 (BCL2L11) OTNQQWFJ B2L11_HUMAN Gene/Protein Processing [3]
Bcl2-associated agonist of cell death (BAD) OT63ERYM BAD_HUMAN Gene/Protein Processing [4]
BH3-interacting domain death agonist (BID) OTOSHSHU BID_HUMAN Gene/Protein Processing [3]
Cyclic AMP-dependent transcription factor ATF-4 (ATF4) OTRFV19J ATF4_HUMAN Gene/Protein Processing [5]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Post-Translational Modifications [4]
DNA damage-inducible transcript 3 protein (DDIT3) OTI8YKKE DDIT3_HUMAN Gene/Protein Processing [5]
Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1) OTM0GDTP IF2A_HUMAN Post-Translational Modifications [5]
Histone H2AX (H2AX) OT18UX57 H2AX_HUMAN Gene/Protein Processing [5]

References

1 In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2). Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6.
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3 Norcantharidin induce apoptosis in human nasopharyngeal carcinoma through caspase and mitochondrial pathway. Environ Toxicol. 2018 Mar;33(3):343-350. doi: 10.1002/tox.22521. Epub 2017 Nov 29.
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