Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM9TN2W)

Drug Name
Propanoic Acid Drug Info
Synonyms
propionic acid; Propanoic acid; 1979/9/4; ethylformic acid; methylacetic acid; Carboxyethane; Ethanecarboxylic acid; Pseudoacetic acid; Metacetonic acid; Monoprop; Luprosil; Prozoin; Propionoic acid; Acide propionique; Methyl acetic acid; Antischim B; Sentry grain preserver; C3 acid; Tenox P grain preservative; Caswell No. 707; Propionic acid grain preserver; Propionsaeure; Propcorn; Propkorn; propoic acid; Propioic acid; acide propanoique; Propionic acid (natural); Kyselina propionova; Carboxylic acids, C1-5; Acide propioniqu
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
1032
ChEBI ID
CHEBI:30768
CAS Number
CAS 79-09-4
TTD Drug ID
DM9TN2W

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Investigative Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Preclinical Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Mycobacterium Biosynthetic alanine racemase (MycB alr)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cycloserine DMT1I52 Bacterial infection 1A00-1C4Z Approved [2]
Acetate Ion DMD08RH Discovery agent N.A. Investigative [2]
Pyridoxamine-5'-Phosphate DMQ6POC Discovery agent N.A. Investigative [2]
Lysine Nz-Carboxylic Acid DMW1YK3 Discovery agent N.A. Investigative [2]
Propionate DM0O8N6 Discovery agent N.A. Investigative [4]
Pyridoxyl-N,O-Cycloserylamide-5-Monophosphate DM7AW0X Discovery agent N.A. Investigative [2]
N-(5'-Phosphopyridoxyl)-D-Alanine DM3FCAI Discovery agent N.A. Investigative [2]
Pyridoxyl-Alanine-5-Phosphate DMUVCWY Discovery agent N.A. Investigative [2]
3-fluorovinylglycine DMECBLA Discovery agent N.A. Investigative [5]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Krueppel-like factor 11 (KLF11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [6]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [7]
Testosterone DM7HUNW Hot flushes GA30 Approved [8]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [9]
Leflunomide DMR8ONJ Arthritis FA20 Approved [10]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [12]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [13]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [14]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [15]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Embryonal Fyn-associated substrate (EFS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [16]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [12]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [17]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [18]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [19]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [20]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Immunoglobulin mu Fc receptor (FCMR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [21]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [22]
Menthol DMG2KW7 Back pain ME84.Z Approved [23]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [24]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [25]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [26]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [27]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [28]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [29]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [30]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nuclear factor NF-kappa-B p105 subunit (NFKB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [31]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [32]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [33]
Gefitinib DM15F0X Colon adenocarcinoma Approved [34]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [35]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [36]
Methotrexate DM2TEOL Anterior urethra cancer Approved [37]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [38]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [39]
Quercetin DM3NC4M Obesity 5B81 Approved [40]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Achaete-scute homolog 1 (ASCL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [41]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [42]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [43]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [44]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [45]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [46]
Afimoxifene DMFORDT Breast cancer 2C60-2C65 Phase 2 [47]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [18]
THAPSIGARGIN DMDMQIE N. A. N. A. Preclinical [48]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [49]
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Drug(s) Affected By Histone H2B type 1-D (H2BC5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [50]
Quercetin DM3NC4M Obesity 5B81 Approved [51]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [21]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [16]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [52]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [53]
Testosterone DM7HUNW Hot flushes GA30 Approved [54]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [54]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [55]
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Drug(s) Affected By Transcription factor A, mitochondrial (TFAM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [56]
Quercetin DM3NC4M Obesity 5B81 Approved [57]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [58]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [59]
Testosterone DM7HUNW Hot flushes GA30 Approved [8]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [60]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [17]
Chloramphenicol DMFXEWT Bacterial infection 1A00-1C4Z Approved [61]
Zalcitabine DMH7MUV Human immunodeficiency virus infection 1C62 Approved [62]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [63]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Failed axon connections homolog (FAXC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [41]
Panobinostat DM58WKG Chronic graft versus host disease Approved [64]
Testosterone DM7HUNW Hot flushes GA30 Approved [8]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [65]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [25]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [66]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [65]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [67]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [18]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [19]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By General transcription factor II-I repeat domain-containing protein 2B (GTF2IRD2B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [50]
Methotrexate DM2TEOL Anterior urethra cancer Approved [68]
Testosterone DM7HUNW Hot flushes GA30 Approved [8]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [28]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [30]
Drug(s) Affected By Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (LFNG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [69]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [70]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [71]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [16]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [72]
Testosterone DM7HUNW Hot flushes GA30 Approved [54]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [9]
Leflunomide DMR8ONJ Arthritis FA20 Approved [10]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [12]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [15]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Atlastin-1 (ATL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [51]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [59]
Testosterone DM7HUNW Hot flushes GA30 Approved [8]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [65]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [73]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [74]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [45]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [18]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [19]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein FAN (NSMAF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [75]
Panobinostat DM58WKG Chronic graft versus host disease Approved [64]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [42]
Menthol DMG2KW7 Back pain ME84.Z Approved [23]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [25]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [76]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [28]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [65]
Vinblastine DM5TVS3 Advanced cancer 2A00-2F9Z Approved [77]
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Drug(s) Affected By NAD-dependent protein deacetylase sirtuin-1 (SIRT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [78]
Selenium DM25CGV N. A. N. A. Approved [75]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [71]
Quercetin DM3NC4M Obesity 5B81 Approved [79]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [80]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [81]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [82]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [83]
Testosterone DM7HUNW Hot flushes GA30 Approved [8]
Olaparib DM8QB1D Ovarian cancer 2C73 Approved [84]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Bcl-2-modifying factor (BMF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [85]
Panobinostat DM58WKG Chronic graft versus host disease Approved [86]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [87]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [88]
Leflunomide DMR8ONJ Arthritis FA20 Approved [10]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [89]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [90]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [13]
Menthol DMG2KW7 Back pain ME84.Z Approved [23]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cysteine/serine-rich nuclear protein 1 (CSRNP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [59]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [7]
Testosterone DM7HUNW Hot flushes GA30 Approved [54]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [54]
Leflunomide DMR8ONJ Arthritis FA20 Approved [10]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [12]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [92]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [93]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [15]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By BTB/POZ domain-containing protein KCTD15 (KCTD15)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [59]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [94]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [95]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [25]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [66]
Arsenic DMTL2Y1 N. A. N. A. Approved [96]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [28]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [65]
Urethane DM7NSI0 N. A. N. A. Phase 4 [97]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sphingosine 1-phosphate receptor 3 (S1PR3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [98]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [21]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [16]
Panobinostat DM58WKG Chronic graft versus host disease Approved [45]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [12]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [99]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [100]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [101]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [66]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By IQ domain-containing protein N (IQCN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [41]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [7]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [12]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [66]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [102]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [44]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [103]
Urethane DM7NSI0 N. A. N. A. Phase 4 [97]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [104]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [18]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor necrosis factor receptor superfamily member 19 (TNFRSF19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [105]
Quercetin DM3NC4M Obesity 5B81 Approved [51]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [16]
Panobinostat DM58WKG Chronic graft versus host disease Approved [86]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [106]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [51]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [55]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [86]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [107]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [108]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By NAD-dependent protein deacetylase sirtuin-3, mitochondrial (SIRT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [78]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [109]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [110]
Stavudine DM6DEK9 Human immunodeficiency virus infection 1C62 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [12]
Hesperetin DMKER83 High blood cholesterol level 5C80.00 Approved [111]
Chloroquine DMSI5CB Malaria 1F40-1F45 Approved [110]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [15]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [28]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [112]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Core histone macro-H2A.2 (MACROH2A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [75]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [59]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [113]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [90]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [12]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [73]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [15]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [102]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [28]
Urethane DM7NSI0 N. A. N. A. Phase 4 [97]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPARGC1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [51]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [58]
Fructose DM43AN2 Vomiting MD90 Approved [114]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [115]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [80]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [72]
Ketotifen DM74XKS Allergic conjunctivitis 9A60.02 Approved [116]
Riboflavin DM8YMWE Acne vulgaris ED80 Approved [117]
Leflunomide DMR8ONJ Arthritis FA20 Approved [10]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [117]
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Drug(s) Affected By N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (NAGPA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [90]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [12]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [118]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [118]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [44]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [28]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [18]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Mycobacterium Biosynthetic alanine racemase (MycB alr) TT6TMZU ALR_MYCSM Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Achaete-scute homolog 1 (ASCL1) OTI4X44G ASCL1_HUMAN Gene/Protein Processing [3]
Atlastin-1 (ATL1) OTR2788Y ATLA1_HUMAN Gene/Protein Processing [3]
Bcl-2-modifying factor (BMF) OT90NSLI BMF_HUMAN Gene/Protein Processing [3]
Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (LFNG) OTPSUBN2 LFNG_HUMAN Gene/Protein Processing [3]
BTB/POZ domain-containing protein KCTD15 (KCTD15) OTM6L4A0 KCD15_HUMAN Gene/Protein Processing [3]
Core histone macro-H2A.2 (MACROH2A2) OTAKSVYV H2AW_HUMAN Gene/Protein Processing [3]
Cysteine/serine-rich nuclear protein 1 (CSRNP1) OTDK1FPH CSRN1_HUMAN Gene/Protein Processing [3]
Embryonal Fyn-associated substrate (EFS) OT06O7XL EFS_HUMAN Gene/Protein Processing [3]
Failed axon connections homolog (FAXC) OTU0RGB0 FAXC_HUMAN Gene/Protein Processing [3]
General transcription factor II-I repeat domain-containing protein 2B (GTF2IRD2B) OTO0L3A2 GTD2B_HUMAN Gene/Protein Processing [3]

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1062).
2 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
3 Propionic acid induces mitochondrial dysfunction and affects gene expression for mitochondria biogenesis and neuronal differentiation in SH-SY5Y cell line. Neurotoxicology. 2019 Dec;75:116-122. doi: 10.1016/j.neuro.2019.09.009. Epub 2019 Sep 14.
4 Molecular dynamics studies of alanine racemase: a structural model for drug design. Biopolymers. 2003 Oct;70(2):186-200.
5 Mechanism-based inactivation of alanine racemase by 3-halovinylglycines. J Biol Chem. 1991 Nov 15;266(32):21657-65.
6 Arsenic suppresses gene expression in promyelocytic leukemia cells partly through Sp1 oxidation. Blood. 2005 Jul 1;106(1):304-10.
7 THC exposure of human iPSC neurons impacts genes associated with neuropsychiatric disorders. Transl Psychiatry. 2018 Apr 25;8(1):89. doi: 10.1038/s41398-018-0137-3.
8 The exosome-like vesicles derived from androgen exposed-prostate stromal cells promote epithelial cells proliferation and epithelial-mesenchymal transition. Toxicol Appl Pharmacol. 2021 Jan 15;411:115384. doi: 10.1016/j.taap.2020.115384. Epub 2020 Dec 25.
9 Large-scale in silico and microarray-based identification of direct 1,25-dihydroxyvitamin D3 target genes. Mol Endocrinol. 2005 Nov;19(11):2685-95.
10 Endoplasmic reticulum stress and MAPK signaling pathway activation underlie leflunomide-induced toxicity in HepG2 Cells. Toxicology. 2017 Dec 1;392:11-21.
11 Comparison of HepG2 and HepaRG by whole-genome gene expression analysis for the purpose of chemical hazard identification. Toxicol Sci. 2010 May;115(1):66-79.
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