Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMDGPY9)

Drug Name
LINOLEIC ACID Drug Info
Synonyms
linoleic acid; 60-33-3; Linolic acid; Telfairic acid; (9Z,12Z)-octadeca-9,12-dienoic acid; cis,cis-Linoleic acid; Grape seed oil; Linoleate; cis,cis-9,12-Octadecadienoic acid; Emersol 315; cis-9,cis-12-Octadecadienoic acid; 9,12-Linoleic acid; Unifac 6550; 9Z,12Z-Linoleic acid; Extra Linoleic 90; 9-cis,12-cis-Linoleic acid; Polylin 515; Emersol 310; Polylin No. 515; Oils, grape; 9Z,12Z-octadecadienoic acid; alpha-Linoleic acid; all-cis-9,12-Octadecadienoic acid; Linoleic; acide linoleique; (Z,Z)-9,12-Octadecadienoic acid; acido lino
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
5280450
ChEBI ID
CHEMBL267476
CAS Number
CAS 60-33-3
TTD Drug ID
DMDGPY9
INTEDE Drug ID
DR2161

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DME
DOT
Drug Status:
Patented Agent(s)
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Fatty acid-binding protein 4 (FABP4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
PMID27109571-Compound-27 DMXRTH4 N. A. N. A. Patented [13]
PMID27109571-Compound-31 DMU690T N. A. N. A. Patented [13]
PMID27109571-Compound-16 DMZI25U N. A. N. A. Patented [13]
PMID27109571-Compound-14 DMVY6B9 N. A. N. A. Patented [13]
PMID27109571-Compound-25 DM435GR N. A. N. A. Patented [13]
PMID27109571-Compound-30 DM24FSP N. A. N. A. Patented [13]
PMID27109571-Compound-29 DMDMEHQ N. A. N. A. Patented [13]
PMID27109571-Compound-18 DM4S5ME N. A. N. A. Patented [13]
PMID27109571-Compound-28 DMTZVY3 N. A. N. A. Patented [13]
PMID27109571-Compound-20 DMQU9XP N. A. N. A. Patented [13]
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Drug(s) Affected By Cytochrome P450 2C19 (CYP2C19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [14]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [15]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [16]
Chloramphenicol DMFXEWT Bacterial infection 1A00-1C4Z Approved [17]
Capsaicin DMGMF6V Back pain ME84.Z Approved [18]
Pentamidine DMHZJCG African trypanosomiasis 1F51 Approved [19]
Stiripentol DMMSDOY Dravet syndrome 8A61.11 Approved [20]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [19]
Desipramine DMT2FDC Attention deficit hyperactivity disorder 6A05.Z Approved [15]
Amitriptyline DMK7F9S Depression 6A70-6A7Z Approved [21]
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Drug(s) Affected By Stearoyl-CoA desaturase (SCD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clavulanate DM2FGRT Bacteremia 1A73 Approved [22]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [23]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [23]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [25]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [26]
Fluoxetine DM3PD2C Bipolar depression Approved [23]
Fructose DM43AN2 Vomiting MD90 Approved [27]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [28]
Bupropion DM5PCS7 Depression 6A70-6A7Z Approved [23]
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Drug(s) Affected By Phospholipid-transporting ATPase ABCA1 (ABCA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [29]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [30]
Quercetin DM3NC4M Obesity 5B81 Approved [25]
Fluoxetine DM3PD2C Bipolar depression Approved [31]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [32]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [33]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [34]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [35]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [36]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [37]
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Drug(s) Affected By Fatty acid-binding protein, heart (FABP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluoxetine DM3PD2C Bipolar depression Approved [31]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [38]
Panobinostat DM58WKG Chronic graft versus host disease Approved [39]
Haloperidol DM96SE0 Delirium Approved [40]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [41]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [42]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [43]
Benzatropine DMF7EXL Parkinsonian disorder Approved [40]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [44]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [45]
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Drug(s) Affected By Choriogonadotropin subunit beta 3 (CGB3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [28]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [46]
Testosterone enanthate DMB6871 N. A. N. A. Approved [47]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [48]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [49]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [50]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [49]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [51]
Bezafibrate DMZDCS0 Hypercholesterolaemia 5C80.0 Approved [6]
Testosterone DM7HUNW Hot flushes GA30 Approved [52]
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Drug(s) Affected By C-C motif chemokine 2 (CCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [53]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [54]
Gefitinib DM15F0X Colon adenocarcinoma Approved [55]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [56]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [57]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [58]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [59]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [60]
Quercetin DM3NC4M Obesity 5B81 Approved [61]
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Drug(s) Affected By Type I iodothyronine deiodinase (DIO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [62]
Quercetin DM3NC4M Obesity 5B81 Approved [25]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [64]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [65]
Ergocalciferol DMHO0AR Hypoparathyroidism 5A50 Approved [66]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [67]
Masoprocol DMMVNZ0 Prostate cancer 2C82.0 Approved [66]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [68]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [69]
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Drug(s) Affected By Solute carrier family 22 member 6 (SLC22A6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [70]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [71]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [71]
Quercetin DM3NC4M Obesity 5B81 Approved [72]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [71]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [71]
Succinic acid DMDWICP Malnutrition 5B50-5B71 Approved [73]
Mefenamic acid DMK7HFI Dysmenorrhea GA34.3 Approved [71]
Probenecid DMMFWOJ Acute gonococcal cervicitis Approved [74]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [71]
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Drug(s) Affected By Organic anion transporter 3 (SLC22A8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valsartan DMREUQ6 Chronic heart failure BD1Z Approved [75]
Methotrexate DM2TEOL Anterior urethra cancer Approved [70]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [76]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [77]
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [78]
Cimetidine DMH61ZB Acid-reflux disorder DA22 Approved [78]
Cefdinir DMJ7A0H Bacterial infection 1A00-1C4Z Approved [79]
Cefaclor DMJXDGC Bacterial infection 1A00-1C4Z Approved [79]
Famotidine DMRL3AB Gastric ulcer DA60 Approved [80]
Tetracycline DMZA017 Acne vulgaris ED80 Approved [81]
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Drug(s) Affected By Type II iodothyronine deiodinase (DIO2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [82]
Quercetin DM3NC4M Obesity 5B81 Approved [83]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [84]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [85]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [48]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [86]
Ergocalciferol DMHO0AR Hypoparathyroidism 5A50 Approved [66]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [87]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [88]
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Drug(s) Affected By Hepatitis A virus cellular receptor 1 (HAVCR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [89]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [90]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [91]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [92]
Gentamicin DMKINJO Bacteremia 1A73 Approved [93]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [94]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [95]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [89]
Arsenic DMTL2Y1 N. A. N. A. Approved [96]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [97]
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Drug(s) Affected By Achaete-scute homolog 2 (ASCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [98]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [48]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [99]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [100]
Bezafibrate DMZDCS0 Hypercholesterolaemia 5C80.0 Approved [6]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [101]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [102]
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Drug(s) Affected By Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPARGC1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [25]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [103]
Fructose DM43AN2 Vomiting MD90 Approved [27]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [104]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [105]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [106]
Ketotifen DM74XKS Allergic conjunctivitis 9A60.02 Approved [107]
Riboflavin DM8YMWE Acne vulgaris ED80 Approved [11]
Leflunomide DMR8ONJ Arthritis FA20 Approved [108]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [11]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Fatty acid-binding protein 4 (FABP4) TTHWMFZ FABP4_HUMAN Inhibitor [2]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Linoleate 10-hydratase (10-LAH) DEWD860 A0A1I9RYU9_LACPN Substrate [3]
Linoleate isomerase (lai) DEQ58KF D2BQ64_LACLK Substrate [4] , [5]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Achaete-scute homolog 2 (ASCL2) OT3D62WB ASCL2_HUMAN Gene/Protein Processing [6]
C-C motif chemokine 2 (CCL2) OTAD2HEL CCL2_HUMAN Gene/Protein Processing [7]
Choriogonadotropin subunit beta 3 (CGB3) OTVM2SU3 CGB3_HUMAN Protein Interaction/Cellular Processes [6]
Cytochrome P450 2C19 (CYP2C19) OTFMJYYE CP2CJ_HUMAN Gene/Protein Processing [8]
Fatty acid-binding protein, heart (FABP3) OT562DA1 FABPH_HUMAN Gene/Protein Processing [6]
Hepatitis A virus cellular receptor 1 (HAVCR1) OT184CRZ HAVR1_HUMAN Protein Interaction/Cellular Processes [9]
Organic anion transporter 3 (SLC22A8) OT8BY933 S22A8_HUMAN Gene/Protein Processing [10]
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPARGC1A) OTHCDQ22 PRGC1_HUMAN Gene/Protein Processing [11]
Phospholipid-transporting ATPase ABCA1 (ABCA1) OT94G6BQ ABCA1_HUMAN Protein Interaction/Cellular Processes [12]
Solute carrier family 22 member 6 (SLC22A6) OTKRCBVM S22A6_HUMAN Gene/Protein Processing [10]

References

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3 Characterization of linoleate 10-hydratase of Lactobacillus plantarum and novel antifungal metabolites. Front Microbiol. 2016 Oct 4;7:1561. eCollection 2016.
4 Cell-associated alpha-amylases of butyrate-producing Firmicute bacteria from the human colon. Microbiology. 2006 Nov;152(Pt 11):3281-3290.
5 Effect of linoleic acid concentration on conjugated linoleic acid production by Butyrivibrio fibrisolvens A38. Appl Environ Microbiol. 2000 Dec;66(12):5226-30.
6 Expression of cFABP and PPAR in trophoblast cells: effect of PPAR ligands on linoleic acid uptake and differentiation. Biochim Biophys Acta. 2005 Feb 21;1687(1-3):181-94. doi: 10.1016/j.bbalip.2004.11.017.
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9 In vitro toxicological assessment of free 3-MCPD and select 3-MCPD esters on human proximal tubule HK-2 cells. Cell Biol Toxicol. 2020 Jun;36(3):209-221. doi: 10.1007/s10565-019-09498-0. Epub 2019 Nov 5.
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22 Molecular mechanisms of hepatotoxic cholestasis by clavulanic acid: Role of NRF2 and FXR pathways. Food Chem Toxicol. 2021 Dec;158:112664. doi: 10.1016/j.fct.2021.112664. Epub 2021 Nov 9.
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24 The contribution of methotrexate exposure and host factors on transcriptional variance in human liver. Toxicol Sci. 2007 Jun;97(2):582-94.
25 Comparison of phenotypic and transcriptomic effects of false-positive genotoxins, true genotoxins and non-genotoxins using HepG2 cells. Mutagenesis. 2011 Sep;26(5):593-604.
26 Rofecoxib modulates multiple gene expression pathways in a clinical model of acute inflammatory pain. Pain. 2007 Mar;128(1-2):136-47.
27 Effects of four-week high-fructose diet on gene expression in skeletal muscle of healthy men. Diabetes Metab. 2008 Feb;34(1):82-5. doi: 10.1016/j.diabet.2007.08.004. Epub 2007 Dec 11.
28 Differential modulation of PI3-kinase/Akt pathway during all-trans retinoic acid- and Am80-induced HL-60 cell differentiation revealed by DNA microarray analysis. Biochem Pharmacol. 2004 Dec 1;68(11):2177-86.
29 Atheroprotective effects of methotrexate on reverse cholesterol transport proteins and foam cell transformation in human THP-1 monocyte/macrophages. Arthritis Rheum. 2008 Dec;58(12):3675-83.
30 Combining simvastatin with the farnesyltransferase inhibitor tipifarnib results in an enhanced cytotoxic effect in a subset of primary CD34+ acute myeloid leukemia samples. Clin Cancer Res. 2009 May 1;15(9):3076-83. doi: 10.1158/1078-0432.CCR-08-3004. Epub 2009 Apr 21.
31 Screening autism-associated environmental factors in differentiating human neural progenitors with fractional factorial design-based transcriptomics. Sci Rep. 2023 Jun 29;13(1):10519. doi: 10.1038/s41598-023-37488-0.
32 Pharmacotoxicology of clinically-relevant concentrations of obeticholic acid in an organotypic human hepatocyte system. Toxicol In Vitro. 2017 Mar;39:93-103.
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34 Proton pump inhibitor lansoprazole is a nuclear liver X receptor agonist. Biochem Pharmacol. 2010 May 1;79(9):1310-6. doi: 10.1016/j.bcp.2009.12.018. Epub 2010 Jan 8.
35 Repression of hepatocyte nuclear factor 4 alpha by AP-1 underlies dyslipidemia associated with retinoic acid. J Lipid Res. 2019 Apr;60(4):794-804. doi: 10.1194/jlr.M088880. Epub 2019 Feb 1.
36 Pregnane X receptor-agonists down-regulate hepatic ATP-binding cassette transporter A1 and scavenger receptor class B type I. Biochem Biophys Res Commun. 2005 Jun 17;331(4):1533-41. doi: 10.1016/j.bbrc.2005.04.071.
37 Inhibition of liver x receptor/retinoid X receptor-mediated transcription contributes to the proatherogenic effects of arsenic in macrophages in vitro. Arterioscler Thromb Vasc Biol. 2010 Jun;30(6):1228-36. doi: 10.1161/ATVBAHA.110.205500. Epub 2010 Mar 25.
38 Effects of troglitazone on cellular differentiation, insulin signaling, and glucose metabolism in cultured human skeletal muscle cells. Biochem Biophys Res Commun. 2001 Jan 26;280(3):664-74. doi: 10.1006/bbrc.2000.4216.
39 A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors. Arch Toxicol. 2015 Sep;89(9):1599-618.
40 Cannabidiol Displays Proteomic Similarities to Antipsychotics in Cuprizone-Exposed Human Oligodendrocytic Cell Line MO3.13. Front Mol Neurosci. 2021 May 28;14:673144. doi: 10.3389/fnmol.2021.673144. eCollection 2021.
41 Integrative "-Omics" analysis in primary human hepatocytes unravels persistent mechanisms of cyclosporine A-induced cholestasis. Chem Res Toxicol. 2016 Dec 19;29(12):2164-2174.
42 Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach. Arch Toxicol. 2013 Jan;87(1):123-43.
43 Transcriptomics hit the target: monitoring of ligand-activated and stress response pathways for chemical testing. Toxicol In Vitro. 2015 Dec 25;30(1 Pt A):7-18.
44 CXCL14 downregulation in human keratinocytes is a potential biomarker for a novel in vitro skin sensitization test. Toxicol Appl Pharmacol. 2020 Jan 1;386:114828. doi: 10.1016/j.taap.2019.114828. Epub 2019 Nov 14.
45 Identification of mechanisms of action of bisphenol a-induced human preadipocyte differentiation by transcriptional profiling. Obesity (Silver Spring). 2014 Nov;22(11):2333-43.
46 The psychoactive compound of Cannabis sativa, (9)-tetrahydrocannabinol (THC) inhibits the human trophoblast cell turnover. Toxicology. 2015 Aug 6;334:94-103. doi: 10.1016/j.tox.2015.06.005. Epub 2015 Jun 9.
47 Pharmacological doses of testosterone upregulated androgen receptor and 3-Beta-hydroxysteroid dehydrogenase/delta-5-delta-4 isomerase and impaired leydig cells steroidogenesis in adult rats. Toxicol Sci. 2011 Jun;121(2):397-407. doi: 10.1093/toxsci/kfr063. Epub 2011 Apr 6.
48 Integrative omics data analyses of repeated dose toxicity of valproic acid in vitro reveal new mechanisms of steatosis induction. Toxicology. 2018 Jan 15;393:160-170.
49 Trialkyltin compounds bind retinoid X receptor to alter human placental endocrine functions. Mol Endocrinol. 2005 Oct;19(10):2502-16.
50 Peroxisome proliferator activated receptor gamma (PPAR-gama) ligand pioglitazone regulated gene networks in term human primary trophoblast cells. Reprod Toxicol. 2018 Oct;81:99-107.
51 Activation of AIFM2 enhances apoptosis of human lung cancer cells undergoing toxicological stress. Toxicol Lett. 2016 Sep 6;258:227-236.
52 The inhibitory effects of manganese on steroidogenesis in rat primary Leydig cells by disrupting steroidogenic acute regulatory (StAR) protein expression. Toxicology. 2003 May 3;187(2-3):139-48. doi: 10.1016/s0300-483x(03)00063-5.
53 Some HIV antiretrovirals increase oxidative stress and alter chemokine, cytokine or adiponectin production in human adipocytes and macrophages. Antivir Ther. 2007;12(4):489-500.
54 Arsenite and cadmium promote the development of mammary tumors. Carcinogenesis. 2020 Jul 14;41(7):1005-1014. doi: 10.1093/carcin/bgz176.
55 Crosstalk between alveolar macrophages and alveolar epithelial cells/fibroblasts contributes to the pulmonary toxicity of gefitinib. Toxicol Lett. 2021 Mar 1;338:1-9. doi: 10.1016/j.toxlet.2020.11.011. Epub 2020 Nov 25.
56 Oxidative Stress Alters miRNA and Gene Expression Profiles in Villous First Trimester Trophoblasts. Biomed Res Int. 2015;2015:257090. doi: 10.1155/2015/257090. Epub 2015 Aug 3.
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