Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMZHUO5)

Drug Name
Phenylephrine Drug Info
Synonyms
Cyclomydril; Dilatair; Dionephrine; Doktors; Duration; Fenilefrina; Isophrim; Isophrin; Mesaton; Mesatone; Mesatonum; Metaoxedrin; Metaoxedrine; Metaoxedrinum; Metasympatol; Metasynephrine; Metsatonum; Mezaton; Mydfrin; Neofrin; Neosynephrine; Nostril; Ocugestrin; Phenoptic; Phenylephrinum; Spersaphrine; Visadron; Alcon Efrin; Isopto Frin; Minims Phenylephrine; Nostril Spray Pump; Nostril Spray Pump Mild; Phenylephrine Minims; Prefrin Liquifilm; Relief Eye Drops for Red Eyes; Alconefrin Nasal Drops 12; Alconefrin Nasal Drops 25; Alconefrin Nasal Drops 50; Alconefrin Nasal Spray 25; Ah-Chew; Ak-dilate; Ak-nefrin; Fenilefrina [INN-Spanish]; I-Phrine; L-Phenylephedrine; L-Phenylephrine; M-Methylaminoethanolphenol; M-Oxedrine; M-Sympathol; M-Sympatol; M-Synephrine; Mydfrin (TN); Neo-Synephrine; Neo-Synephrine Nasal Drops; Neo-Synephrine Nasal Jelly; Neo-Synephrine Nasal Spray; Ocu-Phrin Sterile Eye Drops; Phenylephrine (INN); Phenylephrine Minims (TN); Phenylephrine [INN:BAN]; Phenylephrinum [INN-Latin]; R(-)-Phenylephrine; L-(3-Hydroxyphenyl)-N-methylethanolamine; L-1-(m-Hydroxyphenyl)-2-methylaminoethanol; L-m-Hydroxy-alpha-((methylamino)methyl)benzyl alcohol; L-alpha-Hydroxy-beta-methylamino-3-hydroxy-L-ethylbenzene; Tannins, compds. with (R)-3-hydroxy-alpha-((methylamino)methyl)benzenemethanol; Benzenemethanol, 3-hydroxy-alpha-((methylamino)methyl)-, (R)-(9CI); (-)-m-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol; (R)-2-Hydroxy-2-(3-hydroxyphenyl)-N-methylethylamine; (R)-3-Hydroxy-alpha-((methylamino)methyl)benzenemethanol; 3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol
Indication
Disease Entry ICD 11 Status REF
Allergic rhinitis CA08.0 Approved [1]
Arrhythmia BC9Z Approved [1]
Common cold CA00 Approved [1]
Cough MD12 Approved [1]
Fecal incontinence ME07 Approved [2]
Fever MG26 Approved [1]
Headache 8A80-8A84 Approved [1]
Mydriasis LA11.62 Approved [1]
Ophthalmic graves disease 5A02.0 Approved [3]
Proctitis DB33.Z Approved [1]
Rhinitis FA20 Approved [1]
Seasonal allergic rhinitis CA08.01 Approved [1]
Vasomotor/allergic rhinitis CA08 Approved [1]
Therapeutic Class
Ophthalmologicals
Cross-matching ID
PubChem CID
6041
ChEBI ID
CHEBI:8093
CAS Number
CAS 61-76-7
TTD Drug ID
DMZHUO5
VARIDT Drug ID
DR01201
ACDINA Drug ID
D00528

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting Dopamine D2 receptor (D2R)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [9]
Haloperidol DM96SE0 Delirium Approved [10]
Perphenazine DMA4MRX Schizophrenia 6A20 Approved [11]
Perazine DM2AOTZ Psychotic disorder 6A20-6A25 Approved [12]
Domperidone DMBDPY0 Gastrointestinal disease DE2Z Approved [13]
Levodopa DMN3E57 Parkinson disease 8A00.0 Approved [14]
Quetiapine DM1N62C Anorexia nervosa cachexia 6B80 Approved [15]
Pimozide DMW83TP Schizophrenia 6A20 Approved [16]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [17]
Iloperidone DM6AUFY Schizophrenia 6A20 Approved [18]
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Drug(s) Affected By Apoptosis-inducing factor 1, mitochondrial (AIFM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [19]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [20]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [21]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [22]
Quercetin DM3NC4M Obesity 5B81 Approved [23]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [24]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [25]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [26]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [27]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [28]
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Drug(s) Affected By Renin (REN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [29]
Acebutolol DM0TI4U Hypertension BA00-BA04 Approved [30]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [31]
Reboxetine DM26PRD Depression 6A70-6A7Z Approved [32]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [33]
Ramipril DM2R68E Acute heart failure BD10-BD13 Approved [34]
Rhucin DM3ADGP Erectile dysfunction HA01.1 Approved [35]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [36]
Epinephrine DM3KJBC Acute asthma CA23 Approved [37]
Chlorthalidone DM4DMBT Edema MG29 Approved [38]
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Drug(s) Affected By Carbonic anhydrase 1 (CA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [39]
Irbesartan DMTP1DC Diabetic kidney disease GB61.Z Approved [40]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [41]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [42]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [43]
Candesartan DMRK8OT Chronic heart failure BD1Z Approved [40]
Indomethacin DMSC4A7 Bursitis Approved [44]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [45]
GUAIACOL DMN4E7T N. A. N. A. Phase 3 [42]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [46]
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Drug(s) Affected By Carbonic anhydrase 2 (CA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetazolamide DM1AF5U Absence epilepsy Approved [44]
Epinephrine DM3KJBC Acute asthma CA23 Approved [47]
Quercetin DM3NC4M Obesity 5B81 Approved [48]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [49]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [50]
Methazolamide DM7J2TA Glaucoma/ocular hypertension 9C61 Approved [51]
Topiramate DM82Z30 Alcohol dependence 6C40.2 Approved [52]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [53]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [41]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [28]
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Drug(s) Affected By Transforming growth factor beta-1 proprotein (TGFB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [54]
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [55]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [57]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [58]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [59]
Prednisone DM2HG4X Acute asthma CA23 Approved [60]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [61]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [62]
Methotrexate DM2TEOL Anterior urethra cancer Approved [63]
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Drug(s) Affected By Natriuretic peptides A (NPPA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [64]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [65]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Cilazapril DM4V6JA Congestive heart failure BD10 Approved [68]
Lisinopril DMUOK4C Chronic heart failure BD1Z Approved [69]
Irbesartan DMTP1DC Diabetic kidney disease GB61.Z Approved [70]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [73]
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Drug(s) Affected By Fibronectin (FN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [74]
Methotrexate DM2TEOL Anterior urethra cancer Approved [63]
Quercetin DM3NC4M Obesity 5B81 Approved [75]
Aripiprazole DM3NUMH Bipolar I disorder Approved [76]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [77]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [78]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [24]
Ethacrynic acid DM60QMR Edema MG29 Approved [79]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [80]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [81]
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Drug(s) Affected By Apoptosis regulator Bcl-2 (BCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [82]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [83]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [84]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [85]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [55]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [86]
Verapamil DMA7PEW Angina pectoris BA40 Approved [87]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [88]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [89]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [90]
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Drug(s) Affected By Matrix metalloproteinase-9 (MMP9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [91]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [92]
Gefitinib DM15F0X Colon adenocarcinoma Approved [93]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Selenium DM25CGV N. A. N. A. Approved [95]
Pentosan Polysulfate DM2HRKE Interstitial cystitis GC00.3 Approved [96]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [97]
Methotrexate DM2TEOL Anterior urethra cancer Approved [98]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [99]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [100]
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Drug(s) Affected By Alpha-1D adrenergic receptor (ADRA1D)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Alfuzosin DMZVMKF Benign prostatic hyperplasia GA90 Approved [101]
Verapamil DMA7PEW Angina pectoris BA40 Approved [102]
Epinephrine DM3KJBC Acute asthma CA23 Approved [5]
Oxymetazoline DM8ZXT6 Arrhythmia BC9Z Approved [103]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Terbutaline DMD4381 Asthma CA23 Approved [104]
Methoxamine DMF5XQH Hypertension BA00-BA04 Approved [103]
Quinidine DMLPICK N. A. N. A. Approved [102]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [104]
Norepinephrine DMOUC09 Alopecia ED70 Approved [103]
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Drug(s) Affected By Alpha-1A adrenergic receptor (ADRA1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tamsulosin DM5QF9V Benign prostatic hyperplasia GA90 Approved [105]
SILODOSIN DMJSBT6 Benign prostatic hyperplasia GA90 Approved [5]
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [55]
Verapamil DMA7PEW Angina pectoris BA40 Approved [102]
Epinephrine DM3KJBC Acute asthma CA23 Approved [5]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [106]
Oxymetazoline DM8ZXT6 Arrhythmia BC9Z Approved [105]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [28]
Quinidine DMLPICK N. A. N. A. Approved [102]
Norepinephrine DMOUC09 Alopecia ED70 Approved [101]
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Drug(s) Affected By Alpha-1B adrenergic receptor (ADRA1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [102]
Epinephrine DM3KJBC Acute asthma CA23 Approved [5]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [107]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [53]
Oxymetazoline DM8ZXT6 Arrhythmia BC9Z Approved [108]
Terbutaline DMD4381 Asthma CA23 Approved [104]
Quinidine DMLPICK N. A. N. A. Approved [102]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [104]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [109]
Arsenic DMTL2Y1 N. A. N. A. Approved [110]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [111]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [112]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [113]
Gefitinib DM15F0X Colon adenocarcinoma Approved [114]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [115]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [116]
Etretinate DM2CZFA Keratosis ED56 Approved [117]
Prednisone DM2HG4X Acute asthma CA23 Approved [118]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [119]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [120]
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Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [121]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [122]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [123]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [124]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [125]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [126]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [127]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [128]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [129]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [130]
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Drug(s) Affected By Caspase-2 (CASP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [88]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [131]
Methotrexate DM2TEOL Anterior urethra cancer Approved [132]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [133]
Quercetin DM3NC4M Obesity 5B81 Approved [134]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [135]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [26]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [136]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [138]
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Drug(s) Affected By Caspase-9 (CASP9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [138]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [139]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [86]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [88]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [140]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [141]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [21]
Meloxicam DM2AR7L Arthritis FA20 Approved [142]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [143]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [144]
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Drug(s) Affected By Myosin regulatory light chain 2, atrial isoform (MYL7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Testosterone DM7HUNW Hot flushes GA30 Approved [145]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [145]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [146]
Ximelegatran DMU8ANS Myocardial infarction BA41-BA43 Approved [147]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [148]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [149]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [150]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [151]
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Drug(s) Affected By Apoptosis regulator BAX (BAX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [82]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [130]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [86]
Verapamil DMA7PEW Angina pectoris BA40 Approved [87]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [152]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [140]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [115]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [153]
Meloxicam DM2AR7L Arthritis FA20 Approved [154]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [119]
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Drug(s) Affected By Bcl-2-like protein 1 (BCL2L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [155]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [156]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [21]
Selenium DM25CGV N. A. N. A. Approved [157]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [158]
Methotrexate DM2TEOL Anterior urethra cancer Approved [159]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [160]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [161]
Quercetin DM3NC4M Obesity 5B81 Approved [162]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [163]
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Drug(s) Affected By Receptor-interacting serine/threonine-protein kinase 1 (RIPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [164]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [165]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [166]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [165]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [167]
Ethanol DMDRQZU Chronic pain MG30 Approved [168]
Menthol DMG2KW7 Back pain ME84.Z Approved [169]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [170]
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Drug(s) Affected By Caspase-8 (CASP8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [171]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [172]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [173]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [174]
Gefitinib DM15F0X Colon adenocarcinoma Approved [175]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [176]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [21]
Selenium DM25CGV N. A. N. A. Approved [157]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [143]
Methotrexate DM2TEOL Anterior urethra cancer Approved [63]
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Drug(s) Affected By Nuclear factor of activated T-cells, cytoplasmic 4 (NFATC4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [177]
Panobinostat DM58WKG Chronic graft versus host disease Approved [178]
Vinblastine DM5TVS3 Advanced cancer 2A00-2F9Z Approved [177]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Ethanol DMDRQZU Chronic pain MG30 Approved [179]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [180]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [181]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [178]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [182]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [183]
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Drug(s) Affected By Mixed lineage kinase domain-like protein (MLKL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [184]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [164]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [165]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [185]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [28]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Ethanol DMDRQZU Chronic pain MG30 Approved [186]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [187]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [188]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [189]
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Drug(s) Affected By Bcl2-associated agonist of cell death (BAD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paclitaxel DMLB81S Breast carcinoma Approved [190]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [130]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [174]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [191]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [192]
Quercetin DM3NC4M Obesity 5B81 Approved [193]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [184]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [194]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [135]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [195]
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Drug(s) Affected By Growth/differentiation factor 15 (GDF15)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [196]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [116]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [120]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [197]
Quercetin DM3NC4M Obesity 5B81 Approved [75]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [198]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [199]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [199]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [200]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [201]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Receptor-interacting serine/threonine-protein kinase 3 (RIPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [164]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Ethanol DMDRQZU Chronic pain MG30 Approved [168]
Menthol DMG2KW7 Back pain ME84.Z Approved [169]
Arsenic DMTL2Y1 N. A. N. A. Approved [202]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [45]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [203]
GSK618334 DMJPXZ4 Drug abuse 6C4G.1Z Phase 1 [204]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [46]
OLEIC ACID DM54O1Z Discovery agent N.A. Investigative [205]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pro-adrenomedullin (ADM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [112]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [206]
Methotrexate DM2TEOL Anterior urethra cancer Approved [63]
Quercetin DM3NC4M Obesity 5B81 Approved [48]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [207]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [208]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [209]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [210]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Angiotensinogen (AGT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [211]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [212]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [213]
Reboxetine DM26PRD Depression 6A70-6A7Z Approved [32]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [214]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [215]
Rhucin DM3ADGP Erectile dysfunction HA01.1 Approved [35]
Quercetin DM3NC4M Obesity 5B81 Approved [48]
Lisinopril DMUOK4C Chronic heart failure BD1Z Approved [69]
Irbesartan DMTP1DC Diabetic kidney disease GB61.Z Approved [216]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Angiotensin-converting enzyme (ACE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Trandolapril DM4L6EU Chronic heart failure BD1Z Approved [55]
Fosinopril DM9NJ52 Chronic heart failure BD1Z Approved [55]
Quinapril DMR8H31 Chronic heart failure BD1Z Approved [55]
Cilazapril DM4V6JA Congestive heart failure BD10 Approved [217]
Perindopril DMOPZDT Hypertension BA00-BA04 Approved [218]
Lisinopril DMUOK4C Chronic heart failure BD1Z Approved [219]
Testosterone DM7HUNW Hot flushes GA30 Approved [220]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [221]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [222]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Plasma membrane calcium-transporting ATPase 4 (ATP2B4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [157]
Methotrexate DM2TEOL Anterior urethra cancer Approved [159]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [24]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [136]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [223]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [224]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [187]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [187]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [170]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Beta-3 adrenergic receptor (ADRB3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [225]
Isoproterenol DMK7MEY Atrioventricular block Approved [226]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [45]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [46]
[3H]CGP12177 DMZN1A3 Discovery agent N.A. Investigative [227]
Cyanopindolol DMIBLGH Discovery agent N.A. Investigative [228]
KOJIC ACID DMP84CS Discovery agent N.A. Investigative [229]
[3H]cAMP DMZRQU7 Discovery agent N.A. Investigative [230]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Lipoprotein lipase (LPL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paclitaxel DMLB81S Breast carcinoma Approved [55]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [92]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [231]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [207]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [232]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [233]
Nevirapine DM6HX9B Human immunodeficiency virus infection 1C62 Approved [234]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [235]
Efavirenz DMC0GSJ Human immunodeficiency virus infection 1C62 Approved [234]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pro-opiomelanocortin (POMC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [236]
Prednisone DM2HG4X Acute asthma CA23 Approved [237]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [238]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [239]
Fentanyl DM8WAHT Analgesia MB40.8 Approved [240]
Cyproheptadine DM92AH3 Allergic rhinitis CA08.0 Approved [241]
Triamcinolone DM98IXF Acute adrenal insufficiency Approved [242]
Buspirone DMBS632 Anxiety disorder 6B00-6B0Z Approved [243]
Ethanol DMDRQZU Chronic pain MG30 Approved [244]
Metyrapone DMI7FVQ Cushing disease 5A70 Approved [245]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Caveolin-3 (CAV3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [246]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [247]
ANW-32821 DMMJOZD N. A. N. A. Phase 2 [248]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [249]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Dopamine D2 receptor (D2R) TTEX248 DRD2_HUMAN Agonist [4]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Alpha-1A adrenergic receptor (ADRA1A) OTUIWCL5 ADA1A_HUMAN Gene/Protein Processing [5]
Alpha-1B adrenergic receptor (ADRA1B) OTSAYAFD ADA1B_HUMAN Gene/Protein Processing [5]
Alpha-1D adrenergic receptor (ADRA1D) OTW2CD1O ADA1D_HUMAN Gene/Protein Processing [5]
Angiotensin-converting enzyme (ACE) OTDF1964 ACE_HUMAN Drug Response [6]
Angiotensinogen (AGT) OTBZLYR3 ANGT_HUMAN Drug Response [7]
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Gene/Protein Processing [8]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [8]
Apoptosis-inducing factor 1, mitochondrial (AIFM1) OTKPWB7Q AIFM1_HUMAN Gene/Protein Processing [8]
Bcl-2-like protein 1 (BCL2L1) OTRC5K9O B2CL1_HUMAN Gene/Protein Processing [8]
Bcl2-associated agonist of cell death (BAD) OT63ERYM BAD_HUMAN Gene/Protein Processing [8]

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