Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMG5KDY)

Drug Name
PYROGALLOL Drug Info
Synonyms
pyrogallol; benzene-1,2,3-triol; 87-66-1; 1,2,3-trihydroxybenzene; pyrogallic acid; 1,2,3-benzenetriol; Fouramine Brown AP; fourrine PG; fourrine 85; Pyro; C.I. Oxidation Base 32; Piral; fouramine base ap; C.I. 76515; Benzenetriol; 1,2,3-Trihydroxybenzen; Benzene, 1,2,3-trihydroxy-; CI Oxidation Base 32; NSC 5035; UNII-01Y4A2QXY0; HSDB 794; CCRIS 1940; 2,3-Dihydroxyphenol; 1,2,3-Trihydroxybenzen [Czech]; 1,2,3-TRIHYDROXY-BENZENE; Pyrogallol, ACS reagent; EINECS 201-762-9; BRN 0907431; CI 76515; AI3-00709; CHEMBL307145; 01Y4A2QXY0
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
1057
ChEBI ID
CHEBI:16164
CAS Number
CAS 87-66-1
TTD Drug ID
DMG5KDY
INTEDE Drug ID
DR2253

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Arachidonate 5-lipoxygenase (5-LOX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zileuton DMVRIC2 Allergic asthma CA23.0 Approved [7]
Diethylcarbamazine DM1TJ8F Elephantiasis Approved [8]
Silymarin DMXBYQR N. A. N. A. Phase 4 [9]
3,4-Dihydroxycinnamic Acid DMVZL26 Thrombocytopenia 3B64 Phase 4 [10]
Avastin+/-Tarceva DMA86FL Non-small-cell lung cancer 2C25.Y Phase 3 [1]
ABT-761 DM3FIC2 Asthma CA23 Phase 3 [11]
Tenidap DMHQRYE Rheumatoid arthritis FA20 Phase 3 [12]
FPL-62064 DMGF8MZ Inflammation 1A00-CA43.1 Phase 3 [13]
Flobufen DMPSG4D Rheumatoid arthritis FA20 Phase 3 [14]
Darbufelone DMYVKM5 Asthma CA23 Phase 2/3 [15]
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Drug(s) Metabolized By Glucansucrase (gtf106B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sucrose DMVWUCF Discovery agent N.A. Investigative [16]
RESORCINOL DMM37C0 Discovery agent N.A. Investigative [17]
CATECHOL DML0YEK Discovery agent N.A. Investigative [18]
ETHYLGALLATE DMJ6PB8 Discovery agent N.A. Investigative [19]
Drug(s) Affected By Catalase (CAT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [20]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [21]
Haloperidol DM96SE0 Delirium Approved [22]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [23]
Selenium DM25CGV N. A. N. A. Approved [24]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [25]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [26]
Methotrexate DM2TEOL Anterior urethra cancer Approved [27]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [28]
Quercetin DM3NC4M Obesity 5B81 Approved [29]
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Drug(s) Affected By Cellular tumor antigen p53 (TP53)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [30]
Methotrexate DM2TEOL Anterior urethra cancer Approved [27]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [31]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [32]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [33]
Paclitaxel DMLB81S Breast carcinoma Approved [34]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [35]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [36]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [37]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [38]
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Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [39]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [40]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [41]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [33]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [42]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [43]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [44]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [45]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [46]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [47]
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Drug(s) Affected By Cytochrome c (CYCS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [48]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [49]
Gefitinib DM15F0X Colon adenocarcinoma Approved [50]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [51]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [52]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [53]
Methotrexate DM2TEOL Anterior urethra cancer Approved [27]
Quercetin DM3NC4M Obesity 5B81 Approved [29]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [54]
Pefloxacin DM49IGF Gonococcal urethritis 1A70.0Y Approved [55]
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Drug(s) Affected By Caspase-8 (CASP8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [56]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [57]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [58]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [48]
Gefitinib DM15F0X Colon adenocarcinoma Approved [59]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [60]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [61]
Selenium DM25CGV N. A. N. A. Approved [62]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [63]
Methotrexate DM2TEOL Anterior urethra cancer Approved [27]
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Drug(s) Affected By Nuclear factor erythroid 2-related factor 2 (NFE2L2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [64]
Verapamil DMA7PEW Angina pectoris BA40 Approved [65]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [66]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [20]
Selenium DM25CGV N. A. N. A. Approved [62]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [67]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [68]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [69]
Quercetin DM3NC4M Obesity 5B81 Approved [29]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [70]
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Drug(s) Affected By Catechol O-methyltransferase (COMT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Epinephrine DM3KJBC Acute asthma CA23 Approved [5]
Dobutamine DMD1B8Z Heart failure BD10-BD13 Approved [5]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [5]
Modafinil DMYILBE Malignant glioma 2A00.0 Approved [71]
Levodopa DMN3E57 Parkinson disease 8A00.0 Approved [5]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [72]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [73]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [74]
Tolcapone DM8MNVO Parkinson disease 8A00.0 Approved [75]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [76]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Arachidonate 5-lipoxygenase (5-LOX) TT2J34L LOX5_HUMAN Inhibitor [1]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Glucansucrase (gtf106B) Main DME DEWRN24 Q5SBN3_LACRE Substrate [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [3]
Caspase-8 (CASP8) OTA8TVI8 CASP8_HUMAN Gene/Protein Processing [3]
Catalase (CAT) OTHEBX9R CATA_HUMAN Gene/Protein Processing [4]
Catechol O-methyltransferase (COMT) OTPWKTQG COMT_HUMAN Biotransformations [5]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Gene/Protein Processing [4]
Cytochrome c (CYCS) OTBFALJD CYC_HUMAN Protein Interaction/Cellular Processes [3]
Nuclear factor erythroid 2-related factor 2 (NFE2L2) OT0HENJ5 NF2L2_HUMAN Gene/Protein Processing [6]

References

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