Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMLKSE0)

Drug Name
Hexachlorophene Drug Info
Synonyms
Acigena; Almederm; Armohex; Bilevon; Bivelon; Cotofilm; Dermadex; Distodin; Eleven; Esaclorofene; Exofene; Fascol; Fomac; Fostril; Gamophen; Gamophene; Hexabalm; Hexachlorofen; Hexachlorophane; Hexachlorophen; Hexachlorophenum; Hexaclorofeno; Hexafen; Hexascrub; Hexide; Hexophene; Hexosan; Isobac; Nabac; PHisoHex; Phisodan; Ritosept; Septisol; Septofen; Steral; Steraskin; Surofene; TRICHLOROPHENE; Tersaseptic; Trisophen; Turgex; Blockade Anti Bacterial Finish; Brevity Blue Liquid Bacteriostatic Scouring Cream; Brevity Blue Liquid Sanitizing Scouring Cream; Enditch Pet Shampoo; Esaclorofene [DCIT]; Fo stril; Hexachlorofen [Czech]; Hexachlorophene [INN]; Hilo Cat Flea Powder; Hilo Flea Powder; Neosept V; Pedigree Dog Shampoo Bar; Scrubteam Surgical Spongebrush; Staphene O; AT 7; B 32; H3P; Hexachlorophene [UN2875] [Poison]; KUC106447N; M0219; Nabac 25 ec; AT-7; AT17 (TN); AT7 (TN); Acigena (TN); Almederm (TN); At-17; B & b Flea Kontroller for Dogs Only; B 32 (VAN); Bilevon (TN); E-Z Scrub; En-Viron D Concentrated Phenolic Disinfectant; Exofene (TN); Fesia-sin; Fostril (TN); G-11; G-Eleven; G-II; Gamophen (TN); Germa-Medica; Hexa-Germ; Hexachlorophene, Pharma; Hexachlorophenum [INN-Latin]; Hexaclorofeno [INN-Spanish]; Hexaphene-LV; Hexosan (TN); PRE-OP II; Phiso-Scrub; Phisohex(TN); Pre-Op; Septi-Soft; Septisol (TN); Solu-Heks; Soy-dome; Ster-zac; Surgi-Cen; Surgi-Cin; Surofene (TN); Thera-Groom Pet Shampoo for Dogs for Veterinary Use Only; G-11 (TN); GERMA-MEDICA (MG); Germa-Medica (TN); Hexachlorophene (USP/INN); KSC-19-051; Methylenebis(3,4,6-trichlorophenol); Bis(2,3,5-tric hloro-6-hydroxyphenyl)methane; Bis(2,3,5-trichloro-6-hydroxyphenyl)methane; Bis(2-hydroxy-3,5,6-trichlorophenyl)methane; Bis(3,5,6-trichloro-2-hydroxyphenyl)methane; Bis-2,3,5-trichlor-6-hydroxyfenylmethan; Bis-2,3,5-trichloro-6-hydroxyfenylmethan; Bis-2,3,5-trichloro-6-hydroxyfenylmethan [Czech]; Bis(3,5,6-trichloro-2-hydroxyphenyl)-methane; Methane, bis(2,3,5-trichloro-6-hydroxyphenyl); 2,2',3,3',5,5'-Hexachloro-6,6'-dihydroxydiphenylmethane; 2,2'-Dihydroxy-3,5,6,3',5',6'-hexachlorodiphenylmethane; 2,2'-Methylene bis(3,4,6-trichlorophenol); 2,2'-Methylenebis(3,4,6-trichlorophenol); 2,2'-Methylenebis[3,4,6-trichlorophenol]; 2,2'-methanediylbis(3,4,6-trichlorophenol); 2,2-Methylene-bis-[3,4,6-trichlorophenol]; 3,3',5,5',6,6'-Hexachloro-2,2'-dihydroxydiphenylmethane; 3,4,6-trichloro-2-[(2,3,5-trichloro-6-hydroxyphenyl)methyl]phenol
Indication
Disease Entry ICD 11 Status REF
Bacterial infection 1A00-1C4Z Approved [1]
Therapeutic Class
Antiinfective Agents
Cross-matching ID
PubChem CID
3598
ChEBI ID
CHEBI:5693
CAS Number
CAS 70-30-4
TTD Drug ID
DMLKSE0

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Affected By Myc proto-oncogene protein (MYC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [9]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [10]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [11]
Gefitinib DM15F0X Colon adenocarcinoma Approved [12]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [13]
Selenium DM25CGV N. A. N. A. Approved [14]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [15]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [16]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [17]
Methotrexate DM2TEOL Anterior urethra cancer Approved [18]
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Drug(s) Affected By Estrogen receptor (ESR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [19]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [20]
Gefitinib DM15F0X Colon adenocarcinoma Approved [21]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [22]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [23]
Liraglutide DM3FXPS Non-insulin dependent diabetes 5A11 Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [25]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [26]
Procaine DM4LSNE Anaesthesia 9A78.6 Approved [22]
Estrone DM5T6US Acne vulgaris ED80 Approved [27]
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Drug(s) Affected By Cellular tumor antigen p53 (TP53)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [28]
Methotrexate DM2TEOL Anterior urethra cancer Approved [18]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [29]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [30]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [31]
Paclitaxel DMLB81S Breast carcinoma Approved [32]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [33]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [34]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [35]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [36]
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Drug(s) Affected By 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 (HSD3B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [37]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [38]
Testosterone DM7HUNW Hot flushes GA30 Approved [39]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [39]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [41]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [42]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [43]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [44]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [45]
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Drug(s) Affected By Acetylcholinesterase (ACHE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetylcholine DMDF79Z Cataract 9B10 Approved [46]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [47]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [48]
Methotrexate DM2TEOL Anterior urethra cancer Approved [49]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
L-Glutamic Acid DM4PUDW Schizophrenia 6A20 Approved [48]
Tacrine DM51FY6 Alzheimer disease 8A20 Approved [51]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [52]
Neostigmine DM6T2J3 Myasthenia gravis 8C6Y Approved [53]
Testosterone DM7HUNW Hot flushes GA30 Approved [54]
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Drug(s) Affected By G1/S-specific cyclin-D1 (CCND1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [55]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [57]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [20]
Gefitinib DM15F0X Colon adenocarcinoma Approved [58]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [59]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [60]
Selenium DM25CGV N. A. N. A. Approved [61]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [15]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [62]
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Drug(s) Affected By Catenin beta-1 (CTNNB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [63]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [64]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [65]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [68]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [69]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [70]
Testosterone DM7HUNW Hot flushes GA30 Approved [71]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [72]
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Drug(s) Affected By DNA damage-inducible transcript 3 protein (DDIT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [73]
Triacetin DM0AEPG Onychomycosis EE12.1 Approved [74]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [10]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [75]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [76]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [77]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [78]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [79]
Methotrexate DM2TEOL Anterior urethra cancer Approved [80]
Quercetin DM3NC4M Obesity 5B81 Approved [81]
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Drug(s) Affected By TAR DNA-binding protein 43 (TARDBP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [82]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [83]
Doxycycline DM7ICNU Acne vulgaris ED80 Approved [84]
Leflunomide DMR8ONJ Arthritis FA20 Approved [85]
Sorbitol DMAN0DE Constipation DD91.1 Approved [86]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [89]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [90]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [91]
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Drug(s) Affected By kinase isozyme 4, mitochondrial (PDK4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [92]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [93]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [94]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [95]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [96]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [96]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [96]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [97]
Testosterone enanthate DMB6871 N. A. N. A. Approved [98]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
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Drug(s) Affected By E3 ubiquitin-protein ligase SIAH1 (SIAH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [99]
Selenium DM25CGV N. A. N. A. Approved [61]
Quercetin DM3NC4M Obesity 5B81 Approved [92]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [100]
Reserpine DM6VM38 Hypertension BA00-BA04 Approved [101]
Leflunomide DMR8ONJ Arthritis FA20 Approved [85]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [97]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Menthol DMG2KW7 Back pain ME84.Z Approved [102]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [103]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Plasmodium Glutamate dehydrogenase (Malaria gdh) TTAO7YK Q9NGT0_PLAFA Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 (HSD3B1) OTNAZVKB 3BHS1_HUMAN Gene/Protein Processing [3]
Acetylcholinesterase (ACHE) OT2H8HG6 ACES_HUMAN Gene/Protein Processing [4]
Catenin beta-1 (CTNNB1) OTZ932A3 CTNB1_HUMAN Protein Interaction/Cellular Processes [5]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Gene/Protein Processing [6]
DNA damage-inducible transcript 3 protein (DDIT3) OTI8YKKE DDIT3_HUMAN Gene/Protein Processing [7]
E3 ubiquitin-protein ligase SIAH1 (SIAH1) OT29A838 SIAH1_HUMAN Gene/Protein Processing [5]
Estrogen receptor (ESR1) OTKLU61J ESR1_HUMAN Protein Interaction/Cellular Processes [8]
G1/S-specific cyclin-D1 (CCND1) OT8HPTKJ CCND1_HUMAN Gene/Protein Processing [5]
kinase isozyme 4, mitochondrial (PDK4) OTCMHMBZ PDK4_HUMAN Gene/Protein Processing [7]
Myc proto-oncogene protein (MYC) OTPV5LUK MYC_HUMAN Gene/Protein Processing [5]

References

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