Details of the Drug-Related molecule(s) Interaction Atlas

Aminobenzoic acid Drug Info

AMINOBENZOIC ACID; Anti-chromotrichia factor; Anticanitic vitamin; Bacterial vitamin H1; Benzoic acid, 4-amino-; Benzoic acid, p-amino-; Chromotrichia factor; Hachemina; Pabacyd; Pabafilm; Pabamine; Papacidum; Paraminol; Paranate; Potaba; RVPaba Lipstick; Romavit; Rvpaba; Sunbrella; Super Shade by Coppertone; Trichochromogenic factor; Vitamin BX; Vitamin H'; p-Carboxyaniline; p-Carboxyphenylamine; p-aminobenzoic acid; para-aminobenzoic acid; 1-Amino-4-carboxybenzene; 150-13-0; 4-Carboxyaniline; 4-aminobenzoic acid; Amben; PABA

Cross-matching ID

PubChem CID

978

ChEBI ID

CHEBI:30753

CAS Number

CAS 150-13-0

TTD Drug ID

DMNGW2M

INTEDE Drug ID

DR0086

General Information of Drug (ID: DMNGW2M)

Molecule-Related Drug Atlas

Molecule Type:

DME

DOT

Drug Status:

Approved Drug(s)

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Drug(s) Metabolized By RNA cytidine acetyltransferase (hALP)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Folic Acid	DMEMBJC	Colorectal carcinoma		Approved	[5]
Caffeine	DMKBJWP	Allergic rhinitis	CA08.0	Approved	[6]
Procainamide	DMNMXR8	Ventricular arrhythmias	BC71	Approved	[7]
Sulfamethoxazole	DMB08GE	Acute otitis media	AB00	Approved	[8]
Sulfadiazine	DMTW3R8	Rheumatic fever	1B40-1B42	Approved	[9]
Tobramycin	DMUI0CH	Bacteremia	1A73	Approved	[10]
Mesalazine	DMOL5IU	Diverticulitis		Approved	[11]
Allopurinol	DMLPAOB	Gout	FA25	Approved	[12]
Netilmicin	DMRD1QK	Bacterial infection	1A00-1C4Z	Approved	[13]
Clonazepam	DMTO13J	Absence epilepsy		Approved	[14]
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Drug(s) Metabolized By Sulfotransferase 1A1 (SULT1A1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Progesterone	DMUY35B	Amenorrhea	GA20.0	Approved	[15]
Tamoxifen	DMLB0EZ	Breast cancer	2C60-2C65	Approved	[16]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[17]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[18]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[19]
Warfarin	DMJYCVW	Atrial fibrillation	BC81.3	Approved	[20]
Cholic Acid	DM7OKQV	Cholelithiasis	DC11	Approved	[21]
Liothyronine	DM6IR3P	Congenital hypothyroidism		Approved	[22]
Epinephrine	DM3KJBC	Acute asthma	CA23	Approved	[23]
Benzyl alcohol	DMBVYDI	Head and body lice	1G00.0	Approved	[24]
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Drug(s) Affected By Tumor necrosis factor (TNF)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Indomethacin	DMSC4A7	Bursitis		Approved	[25]
Amphotericin B	DMTAJQE	Acne vulgaris	ED80	Approved	[26]
Fructose	DM43AN2	Vomiting	MD90	Approved	[27]
Ketoprofen	DMRKXPT	Bursitis		Approved	[27]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[28]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[29]
Baclofen	DM0QV1J	Multiple sclerosis	8A40	Approved	[30]
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[31]
Ganciclovir	DM1MBYQ	Cytomegalovirus infection	1D82	Approved	[32]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[33]
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Drug(s) Affected By Cyclic AMP-responsive element-binding protein 1 (CREB1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[34]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[35]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[36]
Selenium	DM25CGV	N. A.	N. A.	Approved	[37]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[38]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[39]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[40]
Isotretinoin	DM4QTBN	Acne vulgaris	ED80	Approved	[40]
Hydroquinone	DM6AVR4	Melasma	ED60.1	Approved	[41]
Ergotidine	DM78IME	Osteoarthritis	FA00-FA05	Approved	[42]
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Drug(s) Affected By Nuclear factor NF-kappa-B p105 subunit (NFKB1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Dexamethasone	DMMWZET	Acute adrenal insufficiency		Approved	[43]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[44]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[45]
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[46]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[47]
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[48]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[49]
Dactinomycin	DM2YGNW	Adult kidney Wilms tumor		Approved	[50]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[51]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[52]
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Drug(s) Affected By Arylamine N-acetyltransferase 1 (NAT1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Procainamide	DMNMXR8	Ventricular arrhythmias	BC71	Approved	[53]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[54]
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[55]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[53]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[56]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[56]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[57]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[58]
Folic Acid	DMEMBJC	Colorectal carcinoma		Approved	[53]
Niclosamide	DMJAGXQ	Cestodes infection	1F70-1F76	Approved	[59]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
Sulfotransferase 1A1 (SULT1A1)	DEYWLRK	ST1A1_HUMAN	Substrate	[1]
RNA cytidine acetyltransferase (hALP)	DEZV4AP	NAT10_HUMAN	Substrate	[2]

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Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
Arylamine N-acetyltransferase 1 (NAT1)	OTCCNQ3H	ARY1_HUMAN	Biotransformations	[3]
Cyclic AMP-responsive element-binding protein 1 (CREB1)	OT1MDLA1	CREB1_HUMAN	Gene/Protein Processing	[4]
Nuclear factor NF-kappa-B p105 subunit (NFKB1)	OTNRRD8I	NFKB1_HUMAN	Gene/Protein Processing	[4]
Tumor necrosis factor (TNF)	OT4IE164	TNFA_HUMAN	Gene/Protein Processing	[4]

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