Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMWC4X8)

Drug Name
prostaglandin A2 Drug Info
Synonyms medullin; PGA2
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
5280880
ChEBI ID
CHEBI:27820
CAS Number
CAS 13345-50-1
TTD Drug ID
DMWC4X8
VARIDT Drug ID
DR01369

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Transformation-sensitive protein p120 (TRPA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Menthol DMG2KW7 Back pain ME84.Z Approved [6]
LY3526318 DMFXNQM Chronic low-back pain MG30 Phase 2 [7]
HX-100 DMFRM15 Diabetic neuropathy 8C0Z Phase 1 [8]
NPPB DMFIWAN Discovery agent N.A. Investigative [9]
acetaldehyde DMJFKG4 Discovery agent N.A. Investigative [10]
[3H]resolvin D1 DMFT0HU Discovery agent N.A. Investigative [11]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [12]
icilin DMYVOL9 Discovery agent N.A. Investigative [13]
4-oxo-nonenal DMPX1J9 Discovery agent N.A. Investigative [14]
dibutyl phthalate DMEDGKO Discovery agent N.A. Investigative [15]
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Drug(s) Transported By P-glycoprotein 1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [16]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [17]
Methotrexate DM2TEOL Anterior urethra cancer Approved [18]
Folic Acid DMEMBJC Colorectal carcinoma Approved [19]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [18]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [18]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [20]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [18]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [21]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [22]
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Drug(s) Affected By Tumor necrosis factor (TNF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [23]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [24]
Fructose DM43AN2 Vomiting MD90 Approved [25]
Ketoprofen DMRKXPT Bursitis Approved [25]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [26]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [27]
Baclofen DM0QV1J Multiple sclerosis 8A40 Approved [28]
Gefitinib DM15F0X Colon adenocarcinoma Approved [29]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [30]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [31]
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Drug(s) Affected By Glutathione S-transferase A1 (GSTA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Artemisinin DMOY7W3 Malaria 1F40-1F45 Approved [32]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [33]
Thiotepa DMIZKOP Breast cancer 2C60-2C65 Approved [34]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [35]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [36]
Ethacrynic acid DM60QMR Edema MG29 Approved [37]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [38]
Busulfan DMXYJ9C Chronic myelogenous leukaemia 2A20.0 Approved [39]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [40]
Methotrexate DM2TEOL Anterior urethra cancer Approved [41]
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Drug(s) Affected By Glutathione S-transferase Mu 1 (GSTM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Busulfan DMXYJ9C Chronic myelogenous leukaemia 2A20.0 Approved [42]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [43]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [44]
Ethanol DMDRQZU Chronic pain MG30 Approved [45]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [46]
Methyldopa DM5I621 Hypertension BA00-BA04 Approved [47]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [48]
Testosterone DM7HUNW Hot flushes GA30 Approved [49]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [49]
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Drug(s) Affected By Glutathione S-transferase A2 (GSTA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [50]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [51]
Methotrexate DM2TEOL Anterior urethra cancer Approved [52]
Leflunomide DMR8ONJ Arthritis FA20 Approved [53]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [54]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [55]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [56]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [40]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [57]
Mefenamic acid DMK7HFI Dysmenorrhea GA34.3 Approved [58]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Transformation-sensitive protein p120 (TRPA1) TTELV3W TRPA1_HUMAN Activator [2]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Glutathione S-transferase A1 (GSTA1) OTA7K5XA GSTA1_HUMAN Regulation of Drug Effects [4]
Glutathione S-transferase A2 (GSTA2) OTW7UB1H GSTA2_HUMAN Regulation of Drug Effects [4]
Glutathione S-transferase Mu 1 (GSTM1) OTSBF2MO GSTM1_HUMAN Regulation of Drug Effects [4]
Tumor necrosis factor (TNF) OT4IE164 TNFA_HUMAN Regulation of Drug Effects [5]

References

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