Details of the Drug-Related molecule(s) Interaction Atlas

CLIOQUINOL Drug Info

clioquinol; 130-26-7; 5-Chloro-7-iodoquinolin-8-ol; Iodochlorhydroxyquin; Chinoform; Chloroiodoquin; Chloroiodoquine; 5-Chloro-8-hydroxy-7-iodoquinoline; Iodochloroxyquinoline; Cliquinol; Vioform; Iodochlorohydroxyquinoline; Chlorojodochin; Iodochloroxine; Iodochloroquine; Enteroquinol; Iodoenterol; 7-Iodo-5-chloroxine; Entero-Vioform; 5-Chloro-7-iodo-8-quinolinol; Iodochlorhydroxyquinoline; Iodoxyquinoline; Rheaform; Quinoform; Quinambicide; Lekosept; Dioquinol; Dermaform; Iodenterol; Entrokin; Enteroseptol; Domeform; Barquinol

Cross-matching ID

PubChem CID

2788

ChEBI ID

CHEMBL497

CAS Number

CAS 130-26-7

TTD Drug ID

DM746BZ

INTEDE Drug ID

DR0341

General Information of Drug (ID: DM746BZ)

Molecule-Related Drug Atlas

Molecule Type:

DTT

DME

DOT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Patented Agent(s)

Investigative Drug(s)

Preclinical Drug(s)

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Drug(s) Targeting Carbonic anhydrase (CA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Salicyclic acid	DM2F8XZ	Acne vulgaris	ED80	Approved	[1]
Sulfamylon	DMIO1K0	Bacterial infection	1A00-1C4Z	Approved	[10]
Quinethazone	DMWCOSR	Hypertension	BA00-BA04	Approved	[11]
Curcumin	DMQPH29	Solid tumour/cancer	2A00-2F9Z	Phase 3	[12]
PARABEN	DMEW5Z8	N. A.	N. A.	Phase 3	[13]
PHENOL	DM1QSM3	N. A.	N. A.	Phase 2/3	[12]
Coumate	DMVKW0N	Breast cancer	2C60-2C65	Phase 2	[14]
SULFAMIDE	DMMAS3K	N. A.	N. A.	Phase 1	[15]
FERULIC ACID	DMJC7NF	Discovery agent	N.A.	Patented	[13]
PMID30074415-Compound-21	DM3NPOU	N. A.	N. A.	Patented	[16]
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Drug(s) Targeting Opioid receptor kappa (OPRK1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Nalbuphine	DMOSQGU	Pain	MG30-MG3Z	Approved	[17]
Nalfurafine hcl	DMA9DHW	Uremic pruritus	EC90.10	Approved	[18]
CHLOROXINE	DMFZBMQ	Erythema	ME64.0	Approved	[2]
Difelikefalin	DMHZBEO	Pruritus	EC90	Approved	[19]
Dezocine	DMJDB0Y	Pain	MG30-MG3Z	Approved	[20]
Asimadoline	DMND3AB	Diarrhea-predominant irritable bowel syndrome	DD91.01	Phase 3	[21]
JNJ 67953964	DMJ8Y5N	Major depressive disorder	6A70.3	Phase 3	[22]
PHN-131	DM1SV8I	Pain	MG30-MG3Z	Phase 2/3	[23]
CR-845	DMJYTUQ	Pain	MG30-MG3Z	Phase 2/3	[24]
Carfentanil	DM7ADGX	N. A.	N. A.	Phase 2	[25]
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Drug(s) Metabolized By Sulfotransferase 1A1 (SULT1A1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Progesterone	DMUY35B	Amenorrhea	GA20.0	Approved	[26]
Tamoxifen	DMLB0EZ	Breast cancer	2C60-2C65	Approved	[27]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[28]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[29]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[30]
Warfarin	DMJYCVW	Atrial fibrillation	BC81.3	Approved	[31]
Cholic Acid	DM7OKQV	Cholelithiasis	DC11	Approved	[32]
Liothyronine	DM6IR3P	Congenital hypothyroidism		Approved	[33]
Epinephrine	DM3KJBC	Acute asthma	CA23	Approved	[34]
Benzyl alcohol	DMBVYDI	Head and body lice	1G00.0	Approved	[35]
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Drug(s) Affected By Prolyl 4-hydroxylase subunit alpha-2 (P4HA2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Vitamin C	DMXJ7O8	Adenocarcinoma	2D40	Approved	[36]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[37]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[38]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[39]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[40]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[41]
Ethanol	DMDRQZU	Chronic pain	MG30	Approved	[42]
Zoledronate	DMIXC7G	Adenocarcinoma	2D40	Approved	[43]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[44]
Dexamethasone	DMMWZET	Acute adrenal insufficiency		Approved	[45]
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Drug(s) Affected By BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like (BNIP3L)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[46]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[47]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[48]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[49]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[50]
Zidovudine	DM4KI7O	Human immunodeficiency virus infection	1C62	Approved	[51]
Acetic Acid, Glacial	DM4SJ5Y	infection in the ear canal	AA0Y	Approved	[52]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[53]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[54]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[55]
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Drug(s) Affected By Phosphoglycerate kinase 1 (PGK1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[56]
Etretinate	DM2CZFA	Keratosis	ED56	Approved	[57]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[48]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[58]
Acetic Acid, Glacial	DM4SJ5Y	infection in the ear canal	AA0Y	Approved	[52]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[59]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[60]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[61]
Dihydroartemisinin	DMBXVMZ	Malaria	1F40-1F45	Approved	[62]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[63]
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Drug(s) Affected By Adenylate kinase isoenzyme 1 (AK1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Exemestane	DM9HPW3	Hormonally-responsive breast cancer	2C60-2C65	Approved	[64]
Letrozole	DMH07Y3	Estrogen-receptor positive breast cancer		Approved	[64]
Anastrozole	DMNP60F	Breast cancer	2C60-2C65	Approved	[64]
Aminoglutethimide	DMWFHMZ	Cushing disease	5A70	Approved	[64]
Selenium	DM25CGV	N. A.	N. A.	Approved	[65]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[63]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[41]
Benzatropine	DMF7EXL	Parkinsonian disorder		Approved	[66]
Clozapine	DMFC71L	Schizophrenia	6A20	Approved	[66]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[44]
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Drug(s) Affected By Prolyl hydroxylase EGLN2 (EGLN2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[67]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[67]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[40]
Zoledronate	DMIXC7G	Adenocarcinoma	2D40	Approved	[68]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[69]
Urethane	DM7NSI0	N. A.	N. A.	Phase 4	[70]
Tocopherol	DMBIJZ6	N. A.	N. A.	Phase 2	[65]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[71]
bisphenol A	DM2ZLD7	Discovery agent	N.A.	Investigative	[72]
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Drug(s) Affected By Egl nine homolog 1 (EGLN1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Quercetin	DM3NC4M	Obesity	5B81	Approved	[73]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[50]
Acetic Acid, Glacial	DM4SJ5Y	infection in the ear canal	AA0Y	Approved	[52]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[55]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[74]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[63]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[41]
Ethanol	DMDRQZU	Chronic pain	MG30	Approved	[75]
Motexafin gadolinium	DMEJKRF	Brain cancer	2A00	Approved	[52]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[76]
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Drug(s) Affected By Hypoxia-inducible factor 3-alpha (HIF3A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[56]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[77]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[40]
Isoproterenol	DMK7MEY	Atrioventricular block		Approved	[78]
Menadione	DMSJDTY	Vitamin K deficiency	5B59	Approved	[47]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[79]
Vorinostat	DMWMPD4	Adult acute monocytic leukemia		Approved	[80]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[71]
PMID28460551-Compound-2	DM4DOUB	N. A.	N. A.	Patented	[81]
Trichostatin A	DM9C8NX	Solid tumour/cancer	2A00-2F9Z	Investigative	[82]
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Drug(s) Affected By Copper transport protein ATOX1 (ATOX1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[47]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[39]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[63]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[41]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[76]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[69]
Menadione	DMSJDTY	Vitamin K deficiency	5B59	Approved	[47]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[79]
CERC-801	DM3SZ7P	N. A.	N. A.	Phase 2	[83]
Tocopherol	DMBIJZ6	N. A.	N. A.	Phase 2	[65]
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Drug(s) Affected By Interleukin-8 (CXCL8)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrocortisone	DMGEMB7	Acne vulgaris	ED80	Approved	[84]
Nicotine	DMWX5CO	Lung cancer	2C25.0	Approved	[85]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[86]
Pantothenic acid	DM091H2	Vitamin deficiency	5B55-5B71	Approved	[87]
Mechlorethamine	DM0CVXA	Chronic myelogenous leukaemia	2A20.0	Approved	[88]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[89]
Fexofenadine	DM17ONX	Allergic rhinitis	CA08.0	Approved	[90]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[91]
Nitric Oxide	DM1RBYG	Hypertension	BA00-BA04	Approved	[92]
Lumiracoxib	DM1S4AG	Chronic renal failure	GB61.Z	Approved	[90]
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Drug(s) Affected By Histone H2AX (H2AX)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[93]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[94]
Selenium	DM25CGV	N. A.	N. A.	Approved	[65]
Ribavirin	DMEYLH9	Hepatitis C virus infection	1E51.1	Approved	[95]
Etretinate	DM2CZFA	Keratosis	ED56	Approved	[96]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[97]
Dactinomycin	DM2YGNW	Adult kidney Wilms tumor		Approved	[98]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[99]
Lapatinib	DM3BH1Y	Breast cancer	2C60-2C65	Approved	[100]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[101]
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Drug(s) Affected By Endothelial transcription factor GATA-2 (GATA2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[102]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[49]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[103]
Panobinostat	DM58WKG	Chronic graft versus host disease		Approved	[104]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[105]
Hydroquinone	DM6AVR4	Melasma	ED60.1	Approved	[106]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[55]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[63]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[76]
Decitabine	DMQL8XJ	Acute myelogenous leukaemia	2A41	Approved	[71]
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Drug(s) Affected By Trans-acting T-cell-specific transcription factor GATA-3 (GATA3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[47]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[107]
Rofecoxib	DM3P5DA	Osteoarthritis	FA00-FA05	Approved	[108]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[109]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[110]
Panobinostat	DM58WKG	Chronic graft versus host disease		Approved	[104]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[111]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[112]
Lindane	DMB8CNL	Infestations of lice and scabies	1G00.Z	Approved	[113]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[40]
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Drug(s) Affected By Growth arrest and DNA damage-inducible protein GADD45 alpha (GADD45A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[114]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[115]
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[116]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[117]
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[118]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[119]
Dactinomycin	DM2YGNW	Adult kidney Wilms tumor		Approved	[120]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[121]
Furazolidone	DM3P6V7	Diarrhea	ME05.1	Approved	[122]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[123]
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Drug(s) Affected By Protein-lysine 6-oxidase (LOX)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[124]
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[125]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[48]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[50]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[55]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[39]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[63]
Ethanol	DMDRQZU	Chronic pain	MG30	Approved	[75]
Ampicillin	DMHWE7P	Acute epiglottitis		Approved	[48]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[76]
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Drug(s) Affected By DNA damage-inducible transcript 3 protein (DDIT3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[114]
Triacetin	DM0AEPG	Onychomycosis	EE12.1	Approved	[126]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[115]
Bepridil	DM0RKS4	Chronic/stable angina	BA40.1	Approved	[127]
Indinavir	DM0T3YH	Human immunodeficiency virus infection	1C62	Approved	[128]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[129]
Colchicine	DM2POTE	Acute gout flare	FA25.0	Approved	[130]
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[131]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[132]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[48]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Zidovudine	DM4KI7O	Human immunodeficiency virus infection	1C62	Approved	[133]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[134]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[135]
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[136]
Talazoparib	DM1KS78	Breast cancer	2C60-2C65	Approved	[137]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[129]
Etretinate	DM2CZFA	Keratosis	ED56	Approved	[138]
Prednisone	DM2HG4X	Acute asthma	CA23	Approved	[139]
Ciprofloxacin XR	DM2NLS9	Acute gonococcal cervicitis		Approved	[140]
Colchicine	DM2POTE	Acute gout flare	FA25.0	Approved	[141]
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Drug(s) Affected By Serine-protein kinase ATM (ATM)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[142]
Paromomycin	DM1AGXN	Amoebiasis	1A36	Approved	[143]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[144]
Etretinate	DM2CZFA	Keratosis	ED56	Approved	[138]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[145]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[50]
Remdesivir	DMBFZ6L	Coronavirus Disease 2019 (COVID-19)	1D6Y	Approved	[146]
Acetic Acid, Glacial	DM4SJ5Y	infection in the ear canal	AA0Y	Approved	[52]
Rifampicin	DM5DSFZ	Non-insulin dependent diabetes	5A11	Approved	[147]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[148]
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Drug(s) Affected By Metallothionein-1M (MT1M)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[114]
Deoxycholic acid	DM3GYAL	Subcutaneous fat disorder	EF02	Approved	[149]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[48]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[150]
Phenoxybenzamine	DM8KSQH	Malignant essential hypertension	BA00	Approved	[149]
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[151]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[39]
Disulfiram	DMCL2OK	Alcohol dependence	6C40.2	Approved	[149]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[40]
Dexamethasone	DMMWZET	Acute adrenal insufficiency		Approved	[45]
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Drug(s) Affected By Microtubule-associated proteins 1A/1B light chain 3A (MAP1LC3A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[152]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[153]
Trovafloxacin	DM6AN32	Acute gonococcal cervicitis		Approved	[154]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[155]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[40]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[41]
Capsaicin	DMGMF6V	Back pain	ME84.Z	Approved	[156]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[44]
Chloroquine	DMSI5CB	Malaria	1F40-1F45	Approved	[157]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[76]
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⏷ Show the Full List of 10 Drug(s)

Drug(s) Affected By Hypoxia-inducible factor 1-alpha inhibitor (HIF1AN)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[151]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[74]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[158]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[41]
Isoproterenol	DMK7MEY	Atrioventricular block		Approved	[78]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[159]
Tocopherol	DMBIJZ6	N. A.	N. A.	Phase 2	[65]
bisphenol A	DM2ZLD7	Discovery agent	N.A.	Investigative	[46]
Milchsaure	DM462BT	Pruritus	EC90	Investigative	[160]
Nickel chloride	DMI12Y8	Discovery agent	N.A.	Investigative	[161]
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⏷ Show the Full List of 10 Drug(s)

Drug(s) Affected By COMM domain-containing protein 1 (COMMD1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Quercetin	DM3NC4M	Obesity	5B81	Approved	[48]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[74]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[63]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[76]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[79]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[162]
PMID28460551-Compound-2	DM4DOUB	N. A.	N. A.	Patented	[81]
MG-132	DMKA2YS	N. A.	N. A.	Preclinical	[163]
bisphenol A	DM2ZLD7	Discovery agent	N.A.	Investigative	[46]
BRN-3548355	DM4KXT0	N. A.	N. A.	Investigative	[164]
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⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Carbonic anhydrase (CA)	TTUNARX	NOUNIPROTAC	Inhibitor	[1]
Opioid receptor kappa (OPRK1)	TTQW87Y	OPRK_HUMAN	Inhibitor	[2]

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Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
Sulfotransferase 1A1 (SULT1A1)^{Main DME}	DEYWLRK	ST1A1_HUMAN	Substrate	[3]

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Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
Adenylate kinase isoenzyme 1 (AK1)	OT614AR3	KAD1_HUMAN	Gene/Protein Processing	[4]
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like (BNIP3L)	OTJKOMXE	BNI3L_HUMAN	Gene/Protein Processing	[4]
COMM domain-containing protein 1 (COMMD1)	OT7WUD5R	COMD1_HUMAN	Drug Response	[5]
Copper transport protein ATOX1 (ATOX1)	OT05LF59	ATOX1_HUMAN	Post-Translational Modifications	[6]
Cyclin-dependent kinase inhibitor 1 (CDKN1A)	OTQWHCZE	CDN1A_HUMAN	Gene/Protein Processing	[7]
DNA damage-inducible transcript 3 protein (DDIT3)	OTI8YKKE	DDIT3_HUMAN	Gene/Protein Processing	[8]
Egl nine homolog 1 (EGLN1)	OT5QODDK	EGLN1_HUMAN	Gene/Protein Processing	[4]
Endothelial transcription factor GATA-2 (GATA2)	OTBP2QQ2	GATA2_HUMAN	Gene/Protein Processing	[9]
Growth arrest and DNA damage-inducible protein GADD45 alpha (GADD45A)	OTDRV63V	GA45A_HUMAN	Gene/Protein Processing	[7]
Histone H2AX (H2AX)	OT18UX57	H2AX_HUMAN	Post-Translational Modifications	[7]

------------------------------------------------------------------------------------

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