General Information of Drug (ID: DMF9O6B)

Drug Name
Gallium nitrate Drug Info
Synonyms Ganite (TN)
Indication
Disease Entry ICD 11 Status REF
Hypercalcaemia 5B91.0 Approved [1]
Therapeutic Class
Anticancer Agents
Cross-matching ID
PubChem CID
61635
CAS Number
CAS 13494-90-1
TTD Drug ID
DMF9O6B

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Drug(s) Targeting Interleukin-1 beta (IL1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [4]
Rilonacept DMGLUQS Arthritis FA20 Approved [5]
Canakinumab DM8HLO5 Autosomal dominant familial periodic fever Approved [6]
Diacerein DMN2Q5I N. A. N. A. Phase 4 [7]
XOMA 052 DMOKQV7 Type-2 diabetes 5A11 Phase 3 [8]
ABT-981 DM6PTIX Osteoarthritis FA00-FA05 Phase 2 [9]
AC-201 DMB0TNL Type-2 diabetes 5A11 Phase 2 [10]
LY-2189102 DMU81BH Cardiovascular disease BA00-BE2Z Phase 2 [11]
TT-301 DM4QV8Y Alzheimer disease 8A20 Phase 1 [12]
CYT-013-IL1bQb DMNICD4 Inflammation 1A00-CA43.1 Phase 1 [13]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [16]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [17]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [18]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [19]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [20]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [21]
Capecitabine DMTS85L Adenocarcinoma 2D40 Approved [22]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [23]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [24]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [25]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [26]
Gefitinib DM15F0X Colon adenocarcinoma Approved [27]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [28]
Selenium DM25CGV N. A. N. A. Approved [29]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [30]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [31]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [32]
Methotrexate DM2TEOL Anterior urethra cancer Approved [33]
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Drug(s) Affected By Ferritin light chain (FTL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [34]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [35]
Selenium DM25CGV N. A. N. A. Approved [36]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [38]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [39]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [40]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [16]
Ethanol DMDRQZU Chronic pain MG30 Approved [41]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [42]
Selenium DM25CGV N. A. N. A. Approved [43]
Methotrexate DM2TEOL Anterior urethra cancer Approved [44]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [45]
Epinephrine DM3KJBC Acute asthma CA23 Approved [46]
Quercetin DM3NC4M Obesity 5B81 Approved [47]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [48]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [49]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [50]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [51]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [52]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [53]
Selenium DM25CGV N. A. N. A. Approved [36]
Methotrexate DM2TEOL Anterior urethra cancer Approved [54]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [55]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [56]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [57]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [58]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [59]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [60]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [61]
Etretinate DM2CZFA Keratosis ED56 Approved [62]
Methotrexate DM2TEOL Anterior urethra cancer Approved [63]
Quercetin DM3NC4M Obesity 5B81 Approved [64]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [65]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [66]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [67]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [68]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [56]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [69]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [70]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [17]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [71]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [68]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [39]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [16]
Trabectedin DMG3Y89 Leiomyosarcoma 2B58 Approved [74]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [75]
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Drug(s) Affected By Metallothionein-3 (MT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [77]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [78]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [79]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [80]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [81]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [82]
Arsenic DMTL2Y1 N. A. N. A. Approved [83]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [84]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [85]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [70]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [17]
Quercetin DM3NC4M Obesity 5B81 Approved [86]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [65]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [69]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [87]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [88]
Leflunomide DMR8ONJ Arthritis FA20 Approved [89]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [90]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [91]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [71]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [92]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [39]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [79]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [16]
Trabectedin DMG3Y89 Leiomyosarcoma 2B58 Approved [74]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [75]
Hesperetin DMKER83 High blood cholesterol level 5C80.00 Approved [93]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [36]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [71]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [68]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [94]
Clozapine DMFC71L Schizophrenia 6A20 Approved [95]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [96]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [97]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [98]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [61]
Panobinostat DM58WKG Chronic graft versus host disease Approved [99]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [100]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [96]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [18]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [61]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [19]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [101]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [86]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [68]
Panobinostat DM58WKG Chronic graft versus host disease Approved [102]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [39]
Testosterone DM7HUNW Hot flushes GA30 Approved [103]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [18]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [19]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [84]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [102]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [104]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Interleukin-1 beta (IL1B) TTRYK0X IL1B_HUMAN Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
60 kDa heat shock protein, mitochondrial (HSPD1) OTTO1Y11 CH60_HUMAN Gene/Protein Processing [3]
Cytoplasmic aconitate hydratase (ACO1) OT2VUR7L ACOHC_HUMAN Gene/Protein Processing [3]
DnaJ homolog subfamily A member 1 (DNAJA1) OT38BZQQ DNJA1_HUMAN Gene/Protein Processing [3]
Ferritin light chain (FTL) OTYQA8A6 FRIL_HUMAN Gene/Protein Processing [3]
Heat shock protein beta-1 (HSPB1) OTHFZ8ED HSPB1_HUMAN Gene/Protein Processing [3]
Iron-sulfur clusters transporter ABCB7, mitochondrial (ABCB7) OTDNTHNR ABCB7_HUMAN Gene/Protein Processing [3]
Metallothionein-3 (MT3) OTVCZ7HI MT3_HUMAN Gene/Protein Processing [3]
Myc proto-oncogene protein (MYC) OTPV5LUK MYC_HUMAN Gene/Protein Processing [3]
Phospholipid hydroperoxide glutathione peroxidase GPX4 (GPX4) OTRAFFX2 GPX4_HUMAN Gene/Protein Processing [3]
Popeye domain-containing protein 2 (POPDC2) OTDAZSY5 POPD2_HUMAN Gene/Protein Processing [3]

References

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33 The contribution of methotrexate exposure and host factors on transcriptional variance in human liver. Toxicol Sci. 2007 Jun;97(2):582-94.
34 Cannabidiol induces antioxidant pathways in keratinocytes by targeting BACH1. Redox Biol. 2020 Jan;28:101321. doi: 10.1016/j.redox.2019.101321. Epub 2019 Sep 5.
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48 Rofecoxib modulates multiple gene expression pathways in a clinical model of acute inflammatory pain. Pain. 2007 Mar;128(1-2):136-47.
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64 Identification of biomarkers for the initiation of apoptosis in human preneoplastic colonocytes by proteome analysis. Int J Cancer. 2004 Mar 20;109(2):220-9. doi: 10.1002/ijc.11692.
65 Increased sensitivity for troglitazone-induced cytotoxicity using a human in vitro co-culture model. Toxicol In Vitro. 2009 Oct;23(7):1387-95.
66 Comparison of the gene expression profiles of monocytic versus granulocytic lineages of HL-60 leukemia cell differentiation by DNA microarray analysis. Life Sci. 2003 Aug 15;73(13):1705-19. doi: 10.1016/s0024-3205(03)00515-0.
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68 Temporal changes in gene expression in the skin of patients treated with isotretinoin provide insight into its mechanism of action. Dermatoendocrinol. 2009 May;1(3):177-87.
69 Darinaparsin induces a unique cellular response and is active in an arsenic trioxide-resistant myeloma cell line. Mol Cancer Ther. 2009 May;8(5):1197-206.
70 DNA methylome-wide alterations associated with estrogen receptor-dependent effects of bisphenols in breast cancer. Clin Epigenetics. 2019 Oct 10;11(1):138. doi: 10.1186/s13148-019-0725-y.
71 Transcriptional and Metabolic Dissection of ATRA-Induced Granulocytic Differentiation in NB4 Acute Promyelocytic Leukemia Cells. Cells. 2020 Nov 5;9(11):2423. doi: 10.3390/cells9112423.
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