General Information of Drug (ID: DMZC90M)

Drug Name
PD98059 Drug Info
Synonyms
167869-21-8; PD 98059; 2-(2-amino-3-methoxyphenyl)-4H-chromen-4-one; PD-98059; PD 98,059; 2-(2-amino-3-methoxyphenyl)chromen-4-one; 2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one; 2'-AMINO-3'-METHOXYFLAVONE; PD-098059; 4H-1-Benzopyran-4-one, 2-(2-Amino-3-methoxyphenyl)-; UNII-SJE1IO5E3I; SJE1IO5E3I; CHEMBL35482; C16H13NO3; CHEBI:77954; MFCD00671789; 2-(2-Amino-3-methoxy-phenyl)-chromen-4-one; SR-01000076097; PD 098059; 2-(2-Amino-3-methoxyphenyl)-chromen-4-one; NSC 679829; Tocris-1213; PD098059; Lopac-P-215; BiomolKI_000001; 2-(2-amino-3-methoxy-phenyl)chromen-4-one; BiomolKI2_000011; PD 98,059, solid; Lopac0_001028; BMK1-B1; BSPBio_000996; KBioGR_000336; KBioSS_000336; 2-(2'-amino-3'-methoxyphenyl)oxanaphthalen-4-one; cc-461; MLS006010134; SCHEMBL157826; 4H-1-Benzopyran-4-one,2-(2-amino-3-methoxyphenyl)-; GTPL5241; QCR-14; 2''-amino-3''-methoxyflavone; BCBcMAP01_000049; KBio2_000336; KBio2_002904; KBio2_005472; KBio3_000671; KBio3_000672; AOB2598; DTXSID40168416; BCPP000123; Bio1_000475; Bio1_000964; Bio1_001453; Bio2_000338; Bio2_000818; HMS1362B17; HMS1792B17; HMS1990B17; HMS3229M08; HMS3263M17; HMS3267D03; HMS3403B17; HMS3412O09; HMS3649N14; HMS3654I16; HMS3676O09; BCP02423; EX-A2127; ZINC1420826; Tox21_501028; ABP000927; BDBM50108771; NSC679828; s1177; AKOS015995212; BCP9001060; CCG-100605; CS-0169; LP01028; NSC 679828; NSC-679828; SB16629; SDCCGSBI-0051000.P003; IDI1_002093; SMP2_000052; NCGC00015790-01; NCGC00015790-02; NCGC00015790-03; NCGC00015790-04; NCGC00015790-05; NCGC00015790-06; NCGC00015790-07; NCGC00015790-08; NCGC00025045-01; NCGC00025045-02; NCGC00025045-03; NCGC00025045-04; NCGC00025045-05; NCGC00179347-01; NCGC00261713-01; AC-28412; AK-60664; AS-19374; HY-12028; NCI60_028554; SMR001456459; AB0033706; EU-0101028; FT-0716482; P-215; PD-98059/PD98059/; SW218254-2; X7398; EC-000.2425; A25454; P-4313; PD 98059 & Z-100; InSolution PD 98059 - CAS 167869-21-8; J-505513; SR-01000076097-1; SR-01000076097-3; SR-01000076097-6; 2-(2-amino-3-methoxyphenyl)-4-oxo-4H-[1]benzopyran; BRD-K62810658-001-05-6; BRD-K62810658-001-06-4; Q27088281; 2-(2-Amino-3-methoxy-phenyl)-chromen-4-one(PD98059); PD 98059 - CAS 167869-21-8; 4H-1-Benzopyran-4-one, 2-(2-amino-3-methoxyphenyl)- & Z-100
Indication
Disease Entry ICD 11 Status REF
Cardiac arrest MC82 Investigative [1]
Cross-matching ID
PubChem CID
4713
ChEBI ID
CHEMBL35482
CAS Number
CAS 167869-21-8
TTD Drug ID
DMZC90M

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Clinical Trial Drug(s)
Patented Agent(s)
Discontinued Drug(s)
Investigative Drug(s)
Approved Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selumetinib DMC7W6R Neurofibromatosis type 1 LD2D.10 Phase 3 [11]
Diamidothiazole derivative 1 DM02V5Q N. A. N. A. Patented [12]
Pyridic ketone derivative 1 DM3GU7K N. A. N. A. Patented [13]
RDEA-436 DM0ILRU Solid tumour/cancer 2A00-2F9Z Discontinued in Phase 1 [14]
4,5,6,7-tetrabromo-1H-benzo[d][1,2,3]triazole DMN9YOB Discovery agent N.A. Investigative [15]
DEBROMOHYMENIALDISINE DMDLER8 Discovery agent N.A. Investigative [16]
REVERSINE DMWDNOK Discovery agent N.A. Investigative [17]
OROIDIN DMA2DQT Discovery agent N.A. Investigative [16]
4,5-Dibromo-1H-pyrrole-2-carboxylic acid amide DMDM9UV Discovery agent N.A. Investigative [16]
5-phenylamino-4-cyano-3-hydroxy-isothiazole DMX6R0H Discovery agent N.A. Investigative [18]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Selumetinib DMC7W6R Neurofibromatosis type 1 LD2D.10 Phase 3 [11]
Pyridic ketone derivative 1 DM3GU7K N. A. N. A. Patented [13]
RDEA-436 DM0ILRU Solid tumour/cancer 2A00-2F9Z Discontinued in Phase 1 [14]
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [19]
Topiramate DM82Z30 Alcohol dependence 6C40.2 Approved [20]
Lamotrigine DM8SXYG Bipolar disorder 6A60 Approved [20]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [21]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [22]
Metyrapone DMI7FVQ Cushing disease 5A70 Approved [23]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [19]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [24]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [4]
Levetiracetam DMTGDN8 Epilepsy 8A60-8A68 Approved [22]
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Drug(s) Affected By Tumor protein p73 (TP73)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [25]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [26]
Etretinate DM2CZFA Keratosis ED56 Approved [27]
Quercetin DM3NC4M Obesity 5B81 Approved [28]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [29]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [30]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [31]
Menthol DMG2KW7 Back pain ME84.Z Approved [32]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [33]
Bexarotene DMOBIKY Cutaneous T-cell lymphoma 2B01 Approved [27]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [34]
Gefitinib DM15F0X Colon adenocarcinoma Approved [35]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [36]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [37]
Etretinate DM2CZFA Keratosis ED56 Approved [27]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [38]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [39]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [40]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [42]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [43]
Panobinostat DM58WKG Chronic graft versus host disease Approved [44]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [45]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [46]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [47]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [48]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [7]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [49]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [50]
Indomethacin DMSC4A7 Bursitis Approved [51]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [26]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [52]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [37]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [53]
Quercetin DM3NC4M Obesity 5B81 Approved [54]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [55]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [56]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [57]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [58]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [59]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Pentoxifylline DMU3DNC Alcoholic hepatitis DB94.1 Approved [60]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [61]
Verapamil DMA7PEW Angina pectoris BA40 Approved [62]
Selenium DM25CGV N. A. N. A. Approved [63]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [62]
Quercetin DM3NC4M Obesity 5B81 Approved [64]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [65]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [66]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [67]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [68]
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Drug(s) Affected By Protein c-Fos (FOS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [69]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [70]
Verapamil DMA7PEW Angina pectoris BA40 Approved [71]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [72]
Acebutolol DM0TI4U Hypertension BA00-BA04 Approved [71]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [73]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [74]
Methotrexate DM2TEOL Anterior urethra cancer Approved [75]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [76]
Quercetin DM3NC4M Obesity 5B81 Approved [77]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [78]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [72]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [73]
Gefitinib DM15F0X Colon adenocarcinoma Approved [10]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [79]
Selenium DM25CGV N. A. N. A. Approved [80]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [81]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [82]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [83]
Methotrexate DM2TEOL Anterior urethra cancer Approved [84]
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Drug(s) Affected By Osteocalcin (BGLAP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [85]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [86]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [87]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [88]
Quercetin DM3NC4M Obesity 5B81 Approved [89]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [90]
Pamidronate DMB4AVP Bone Paget disease Approved [91]
Falecalcitrol DMBI9ZJ Hyperparathyroidism 5A51 Approved [92]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [93]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [94]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [95]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [96]
Etretinate DM2CZFA Keratosis ED56 Approved [97]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [98]
Methotrexate DM2TEOL Anterior urethra cancer Approved [99]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [100]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [102]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [103]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [79]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [104]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [105]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [106]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [106]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [7]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [106]
Arsenic DMTL2Y1 N. A. N. A. Approved [109]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [110]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [111]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [112]
Gefitinib DM15F0X Colon adenocarcinoma Approved [113]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [114]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [74]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [82]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [115]
Methotrexate DM2TEOL Anterior urethra cancer Approved [116]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [117]
Quercetin DM3NC4M Obesity 5B81 Approved [118]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [119]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [120]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [55]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [121]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [122]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [123]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Momelotinib DMF98Q0 Myelofibrosis 2A20.2 Approved [124]
Flurbiprofen DMGN4BY Osteoarthritis FA00-FA05 Approved [123]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [125]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [126]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [47]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [127]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [127]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [128]
Wortmannin DM8EVK5 Haematological malignancy 2B33.Y Terminated [126]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [129]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [26]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [130]
cycloheximide DMGDA3C Discovery agent N.A. Investigative [131]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [132]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [133]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [47]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [134]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [135]
Tamibarotene DM3G74J T-cell leukaemia 2A90 Phase 3 [66]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [136]
Maleic Acid DM4L0R7 Discovery agent N.A. Investigative [137]
Rapamycin Immunosuppressant Drug DM678IB Discovery agent N.A. Investigative [133]
PHENCYCLIDINE DMQBEYX Discovery agent N.A. Investigative [138]
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Drug(s) Affected By Cadherin-1 (CDH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [139]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [140]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [141]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [142]
Liraglutide DM3FXPS Non-insulin dependent diabetes 5A11 Approved [143]
Quercetin DM3NC4M Obesity 5B81 Approved [89]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [144]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [145]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [146]
Panobinostat DM58WKG Chronic graft versus host disease Approved [44]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [84]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [147]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [43]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [148]
Testosterone DM7HUNW Hot flushes GA30 Approved [149]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [3]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [149]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [59]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [150]
Flurbiprofen DMGN4BY Osteoarthritis FA00-FA05 Approved [3]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [26]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [151]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [132]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [55]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [69]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [59]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [152]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Gallium nitrate DMF9O6B Hypercalcaemia 5B91.0 Approved [153]
Trabectedin DMG3Y89 Leiomyosarcoma 2B58 Approved [154]
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Drug(s) Affected By Loricrin (LORICRIN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [155]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [156]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [157]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [156]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [158]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [136]
SB 203580 DMAET6F N. A. N. A. Terminated [159]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [89]
Testosterone DM7HUNW Hot flushes GA30 Approved [149]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [149]
Leflunomide DMR8ONJ Arthritis FA20 Approved [160]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [150]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [161]
Arsenic DMTL2Y1 N. A. N. A. Approved [162]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [163]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [164]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [165]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [166]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [167]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [168]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [169]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [170]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [171]
Gefitinib DM15F0X Colon adenocarcinoma Approved [172]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [173]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [174]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [175]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [166]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [176]
Paclitaxel DMLB81S Breast carcinoma Approved [177]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [178]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [165]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [60]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [179]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [168]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [169]
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Drug(s) Affected By CD70 antigen (CD70)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [26]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [180]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [79]
Vemurafenib DM62UG5 Melanoma 2C30 Approved [9]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [181]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [47]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Menthol DMG2KW7 Back pain ME84.Z Approved [32]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [182]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [161]
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Drug(s) Affected By Catenin beta-1 (CTNNB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [183]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [74]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [184]
Quercetin DM3NC4M Obesity 5B81 Approved [185]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [186]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [187]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [188]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [189]
Testosterone DM7HUNW Hot flushes GA30 Approved [190]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [191]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [192]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [70]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [193]
Gefitinib DM15F0X Colon adenocarcinoma Approved [35]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [114]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [194]
Etretinate DM2CZFA Keratosis ED56 Approved [27]
Prednisone DM2HG4X Acute asthma CA23 Approved [195]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [196]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [197]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [95]
Gefitinib DM15F0X Colon adenocarcinoma Approved [10]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [74]
Prednisone DM2HG4X Acute asthma CA23 Approved [195]
Quercetin DM3NC4M Obesity 5B81 Approved [89]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [198]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [199]
Testosterone DM7HUNW Hot flushes GA30 Approved [149]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [149]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [112]
Gefitinib DM15F0X Colon adenocarcinoma Approved [200]
Prednisone DM2HG4X Acute asthma CA23 Approved [195]
Methotrexate DM2TEOL Anterior urethra cancer Approved [201]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [202]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [203]
Quercetin DM3NC4M Obesity 5B81 Approved [204]
Fluoxetine DM3PD2C Bipolar depression Approved [205]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [206]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [207]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [208]
Quercetin DM3NC4M Obesity 5B81 Approved [129]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [132]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [209]
Leflunomide DMR8ONJ Arthritis FA20 Approved [160]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [210]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [211]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [212]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [208]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [213]
Quercetin DM3NC4M Obesity 5B81 Approved [89]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [43]
Panobinostat DM58WKG Chronic graft versus host disease Approved [44]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [214]
Testosterone DM7HUNW Hot flushes GA30 Approved [149]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [215]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [149]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [59]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [150]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor Sp7 (SP7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [86]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [216]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [217]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [47]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [218]
Berberine DMC5Q8X N. A. N. A. Phase 4 [219]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [218]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [136]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [220]
alpha-ketoglutaric acid DM5LFYN Discovery agent N.A. Investigative [221]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [129]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [132]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [59]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [150]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [222]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [163]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [223]
Methotrexate DM2TEOL Anterior urethra cancer Approved [224]
Urethane DM7NSI0 N. A. N. A. Phase 4 [225]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Krueppel-like factor 6 (KLF6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [226]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [227]
Selenium DM25CGV N. A. N. A. Approved [228]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [197]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [229]
Quercetin DM3NC4M Obesity 5B81 Approved [89]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [230]
Panobinostat DM58WKG Chronic graft versus host disease Approved [44]
Leflunomide DMR8ONJ Arthritis FA20 Approved [160]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [59]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [231]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [132]
Panobinostat DM58WKG Chronic graft versus host disease Approved [232]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [38]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [233]
Testosterone DM7HUNW Hot flushes GA30 Approved [149]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [46]
Leflunomide DMR8ONJ Arthritis FA20 Approved [160]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [234]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [47]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
ERK activator kinase 1 (MEK1) TTIDAPM MP2K1_HUMAN Inhibitor [2]
ERK activator kinase 2 (MEK2) TTTW2NY MP2K2_HUMAN Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
15-hydroxyprostaglandin dehydrogenase (HPGD) OTYZI6JB PGDH_HUMAN Gene/Protein Processing [3]
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 (HSD3B2) OT02MSKN 3BHS2_HUMAN Gene/Protein Processing [4]
Apoptosis-inducing factor 1, mitochondrial (AIFM1) OTKPWB7Q AIFM1_HUMAN Protein Interaction/Cellular Processes [5]
Baculoviral IAP repeat-containing protein 5 (BIRC5) OTILXZYL BIRC5_HUMAN Gene/Protein Processing [6]
C-X-C motif chemokine 14 (CXCL14) OTM189TA CXL14_HUMAN Gene/Protein Processing [7]
Cadherin-1 (CDH1) OTFJMXPM CADH1_HUMAN Gene/Protein Processing [8]
Catenin beta-1 (CTNNB1) OTZ932A3 CTNB1_HUMAN Gene/Protein Processing [6]
CD70 antigen (CD70) OTHB2AL1 CD70_HUMAN Gene/Protein Processing [9]
Cyclin-dependent kinase 4 inhibitor B (CDKN2B) OTAG24N1 CDN2B_HUMAN Gene/Protein Processing [10]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Gene/Protein Processing [5]

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