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KRT14 haploinsufficiency results in increased susceptibility of keratinocytes to TNF-alpha-induced apoptosis and causes Naegeli-Franceschetti-Jadassohn syndrome.J Invest Dermatol. 2008 Jun;128(6):1517-24. doi: 10.1038/sj.jid.5701187. Epub 2007 Nov 29.
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Classification of Genes: Standardized Clinical Validity Assessment of Gene-Disease Associations Aids Diagnostic Exome Analysis and Reclassifications. Hum Mutat. 2017 May;38(5):600-608. doi: 10.1002/humu.23183. Epub 2017 Feb 13.
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Quantitative, in situ analysis of mRNAs and proteins with subcellular resolution.Sci Rep. 2017 Nov 28;7(1):16459. doi: 10.1038/s41598-017-16492-1.
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ALDH1-positive intratumoral stromal cells indicate differentiated epithelial-like phenotype and good prognosis in prostate cancer.Transl Res. 2019 Jan;203:49-56. doi: 10.1016/j.trsl.2018.08.007. Epub 2018 Sep 12.
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Keratin 14-high subpopulation mediates lung cancer metastasis potentially through Gkn1 upregulation.Oncogene. 2019 Sep;38(36):6354-6369. doi: 10.1038/s41388-019-0889-0. Epub 2019 Jul 18.
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Buccal cell cytokeratin 14 identifies mild cognitive impairment and Alzheimer' s disease in the AIBL study of aging.Curr Alzheimer Res. 2015;12(3):233-41. doi: 10.2174/1567205012666150302154650.
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IL-33-Induced Atopic Dermatitis-Like Inflammation in Mice Is Mediated by Group 2 Innate Lymphoid Cells in Concert with Basophils.J Invest Dermatol. 2019 Oct;139(10):2185-2194.e3. doi: 10.1016/j.jid.2019.04.016. Epub 2019 May 21.
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The use of mouse models to better understand mechanisms of autoimmunity and tolerance.J Autoimmun. 2010 Nov;35(3):192-8. doi: 10.1016/j.jaut.2010.06.007. Epub 2010 Jul 23.
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MicroRNA-143 and -205 expression in neosquamous esophageal epithelium following Argon plasma ablation of Barrett's esophagus.J Gastrointest Surg. 2009 May;13(5):846-53. doi: 10.1007/s11605-009-0799-5. Epub 2009 Feb 4.
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Differential expression of cytokeratin 14 and 18 in bladder cancer tumorigenesis.Exp Biol Med (Maywood). 2018 Feb;243(4):344-349. doi: 10.1177/1535370218754493. Epub 2018 Jan 19.
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Reporters to mark and eliminate basal or luminal epithelial cells in culture and in vivo.PLoS Biol. 2018 Jun 20;16(6):e2004049. doi: 10.1371/journal.pbio.2004049. eCollection 2018 Jun.
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Combined deletion of Pten and p53 in mammary epithelium accelerates triple-negative breast cancer with dependency on eEF2K.EMBO Mol Med. 2014 Dec;6(12):1542-60. doi: 10.15252/emmm.201404402.
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Prognostic stratification of muscle invasive urothelial carcinomas using limited immunohistochemical panel of Gata3 and cytokeratins 5/6, 14 and 20.Ann Diagn Pathol. 2019 Dec;43:151397. doi: 10.1016/j.anndiagpath.2019.08.001. Epub 2019 Aug 3.
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The Gene Curation Coalition: A global effort to harmonize gene-disease evidence resources. Genet Med. 2022 Aug;24(8):1732-1742. doi: 10.1016/j.gim.2022.04.017. Epub 2022 May 4.
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Revertant mosaicism in junctional epidermolysis bullosa due to multiple correcting second-site mutations in LAMB3.J Clin Invest. 2007 May;117(5):1240-8. doi: 10.1172/JCI30465.
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Fascin and CK4 as biomarkers for esophageal squamous cell carcinoma.Anticancer Res. 2011 Mar;31(3):945-52.
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Activation-induced cytidine deaminase is dispensable for virus-mediated liver and skin tumor development in mouse models.Int Immunol. 2014 Jul;26(7):397-406. doi: 10.1093/intimm/dxu040. Epub 2014 Feb 25.
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Constitutive expression of human keratin 14 gene in mouse lung induces premalignant lesions and squamous differentiation.Carcinogenesis. 2008 Dec;29(12):2377-84. doi: 10.1093/carcin/bgn190. Epub 2008 Aug 12.
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In vivo functional studies of tumor-specific retrogene NanogP8 in transgenic animals.Cell Cycle. 2013 Aug 1;12(15):2395-408. doi: 10.4161/cc.25402. Epub 2013 Jun 26.
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IL-37 ameliorates the inflammatory process in psoriasis by suppressing proinflammatory cytokine production.J Immunol. 2014 Feb 15;192(4):1815-23. doi: 10.4049/jimmunol.1300047. Epub 2014 Jan 22.
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Polyclonal breast cancer metastases arise from collective dissemination of keratin 14-expressing tumor cell clusters.Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):E854-63. doi: 10.1073/pnas.1508541113. Epub 2016 Feb 1.
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Regulation of DNA Damage Signaling and Cell Death Responses by Epstein-Barr Virus Latent Membrane Protein 1 (LMP1) and LMP2A in Nasopharyngeal Carcinoma Cells.J Virol. 2015 Aug;89(15):7612-24. doi: 10.1128/JVI.00958-15. Epub 2015 May 13.
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Novel keratin 14 gene mutations in patients from Hungary with epidermolysis bullosa simplex.Exp Dermatol. 2004 Mar;13(3):185-91. doi: 10.1111/j.0906-6705.2004.0120.x.
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FOXA1 and CK14 as markers of luminal and basal subtypes in histologic variants of bladder cancer and their associated conventional urothelial carcinoma.Virchows Arch. 2017 Sep;471(3):337-345. doi: 10.1007/s00428-017-2190-3. Epub 2017 Jul 18.
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Epidermolysis bullosa simplex with mottled pigmentation resulting from a recurrent mutation in KRT14. J Invest Dermatol. 2006 Jul;126(7):1654-7. doi: 10.1038/sj.jid.5700296. Epub 2006 Apr 6.
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The diagnostic value of cytokeratin 5/6, 14, 17, and 18 expression in human non-small cell lung cancer.Oncology. 2011;80(5-6):333-40. doi: 10.1159/000329098. Epub 2011 Jul 26.
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Indole-3-carbinol prevents cervical cancer in human papilloma virus type 16 (HPV16) transgenic mice.Cancer Res. 1999 Aug 15;59(16):3991-7.
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Epithelial oestrogen receptor is dispensable for the development of oestrogen-induced cervical neoplastic diseases.J Pathol. 2018 Jun;245(2):147-152. doi: 10.1002/path.5069. Epub 2018 Apr 3.
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Biallelic KRT5 mutations in autosomal recessive epidermolysis bullosa simplex, including a complete human keratin 5 "knock-out".Matrix Biol. 2019 Oct;83:48-59. doi: 10.1016/j.matbio.2019.07.002. Epub 2019 Jul 11.
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Disease-linked connexin26 S17F promotes volar skin abnormalities and mild wound healing defects in mice.Cell Death Dis. 2017 Jun 1;8(6):e2845. doi: 10.1038/cddis.2017.234.
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A novel de novo mutation p.Ala428Asp in KRT5 gene as a cause of localized epidermolysis bullosa simplex.Exp Dermatol. 2019 Oct;28(10):1131-1134. doi: 10.1111/exd.13788. Epub 2019 May 20.
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Retinoic acid and its 4-oxo metabolites are functionally active in human skin cells in vitro. J Invest Dermatol. 2005 Jul;125(1):143-53.
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Quantitative proteomics reveals a broad-spectrum antiviral property of ivermectin, benefiting for COVID-19 treatment. J Cell Physiol. 2021 Apr;236(4):2959-2975. doi: 10.1002/jcp.30055. Epub 2020 Sep 22.
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Proteomics-based identification of differentially abundant proteins from human keratinocytes exposed to arsenic trioxide. J Proteomics Bioinform. 2014 Jul;7(7):166-178.
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Impact of extracellular folate levels on global gene expression. Mol Pharmacol. 2001 Dec;60(6):1288-95. doi: 10.1124/mol.60.6.1288.
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Activation of PPAR and inhibition of cell proliferation reduces key proteins associated with the basal subtype of bladder cancer in As3+-transformed UROtsa cells. PLoS One. 2020 Aug 21;15(8):e0237976. doi: 10.1371/journal.pone.0237976. eCollection 2020.
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Exposure to Insecticides Modifies Gene Expression and DNA Methylation in Hematopoietic Tissues In Vitro. Int J Mol Sci. 2023 Mar 26;24(7):6259. doi: 10.3390/ijms24076259.
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Methamphetamine alters the normal progression by inducing cell cycle arrest in astrocytes. PLoS One. 2014 Oct 7;9(10):e109603.
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Oral lichenoid eruption secondary to imatinib (Glivec). J Dermatolog Treat. 2004 Jul;15(4):253-5. doi: 10.1080/09546630410015556.
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Retinoic acid receptor- and retinoid X receptor-selective retinoids activate signaling pathways that converge on AP-1 and inhibit squamous differentiation in human bronchial epithelial cells. Cell Growth Differ. 1996 Aug;7(8):997-1004.
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Proteomic analysis of the cellular response to a potent sensitiser unveils the dynamics of haptenation in living cells. Toxicology. 2020 Dec 1;445:152603. doi: 10.1016/j.tox.2020.152603. Epub 2020 Sep 28.
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Identification of a transcriptomic signature of food-relevant genotoxins in human HepaRG hepatocarcinoma cells. Food Chem Toxicol. 2020 Jun;140:111297. doi: 10.1016/j.fct.2020.111297. Epub 2020 Mar 28.
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Selective inhibition of BET bromodomains. Nature. 2010 Dec 23;468(7327):1067-73.
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Low dose of bisphenol a modulates ovarian cancer gene expression profile and promotes epithelial to mesenchymal transition via canonical Wnt pathway. Toxicol Sci. 2018 Aug 1;164(2):527-538.
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Molecular targets of chloropicrin in human airway epithelial cells. Toxicol In Vitro. 2017 Aug;42:247-254.
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