General Information of Disease (ID: DISQ0M8R)

Disease Name Hepatitis C virus infection
Synonyms chronic hepatitis C; viral hepatitis C; Hepatitis C virus hepatitis; hepatitis C infection; NANBH; non-A, non-B Hepatitis; Hepatitis C virus caused hepatitis; hepatitis Nona nonB; hepatitis type C
Disease Class 1E50-1E51: Hepatitis virus infection
Definition A viral infection caused by the hepatitis C virus.
Disease Hierarchy
DISXXX35: Hepatitis
DISVT5Q7: Viral hepatitis
DISEM33Q: Infectious disease
DISQ0M8R: Hepatitis C virus infection
ICD Code
ICD-11
ICD-11: 1E51.1
ICD-10
ICD-10: B18.2
Disease Identifiers
MONDO ID
MONDO_0005231
MESH ID
D006526
UMLS CUI
C0019196
MedGen ID
42425
SNOMED CT ID
50711007

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 8 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
BOCEPREVIR DMBSHMF Approved Small molecular drug [1]
Daclatasvir DMSFK9V Approved Small molecular drug [2]
Glecaprevir; pibrentasvir DMF6Z5T Approved Combination drug [3]
Merimepodib DM0HS92 Approved Small molecular drug [4]
Peginterferon alfa-2b DMAP58Y Approved NA [5]
PSI-7977 DMLSUWZ Approved Small molecular drug [6]
Ribavirin DMEYLH9 Approved Small molecular drug [7]
Telaprevir DMMRV29 Approved Small molecular drug [8]
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⏷ Show the Full List of 8 Drug(s)
This Disease is Treated as An Indication in 114 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
ABT-267 DMNQ869 Phase 3 Small molecular drug [9]
Albinterferon alfa-2b DMK0QW6 Phase 3 NA [10]
Alisporivir DM83EBP Phase 3 Protein/peptide drug [11]
BI 201335 DM3MXT8 Phase 3 Small molecular drug [12]
Civacir DMKUQU3 Phase 3 NA [13]
Hepatitis C immune globulin DM4LYFJ Phase 3 NA [14]
IMO-2125 DM735FA Phase 3 NA [15]
Interferon alpha 2a DMOTH6V Phase 3 NA [16]
LCQ908 DMFLJHQ Phase 3 Small molecular drug [17]
MK-8742 DMK301H Phase 3 NA [18]
SD-101 DMAMTGI Phase 3 Oligonucleotide [19]
Viramidine DMJFNR9 Phase 3 Small molecular drug [20]
IR208 DM30Z38 Phase 2/3 NA [21]
ANA773 DMSC8YW Phase 2a NA [22]
177Lu-DOTATATE DMT8GVU Phase 2 NA [23]
ABT-384 DM7XW5Y Phase 2 Small molecular drug [24]
ABT-450 DMFW860 Phase 2 NA [25]
ACH-0137171 DMG746H Phase 2 NA [26]
ACH-1625 DMIVUFL Phase 2 Small molecular drug [27]
ACH-3102 DM0RPY5 Phase 2 NA [28]
AP33 DMNVHTY Phase 2 NA [29]
BI 207127 DMMSGAT Phase 2 Small molecular drug [12]
BMS 650032 DMQI43G Phase 2 Small molecular drug [30]
BMS 791325 DMKH4PI Phase 2 Small molecular drug [30]
BMS-824393 DM95F96 Phase 2 NA [31]
CB-5300 DMA86N0 Phase 2 NA [32]
CF102 DMP56WJ Phase 2 Small molecular drug [33]
CIGB-230 DM8NZOW Phase 2 NA [34]
CpG-10101 DM6MUCX Phase 2 NA [35]
Danoprevir DM20MDU Phase 2 Small molecular drug [36]
Filibuvir DMNSYXB Phase 2 Small molecular drug [37]
GI-5005 DMMCEV0 Phase 2 NA [38]
GS-4774 DMUG132 Phase 2 NA [39]
GS-5885 DMSL3DX Phase 2 Small molecular drug [40]
GS-9256 DMCZH5B Phase 2 Small molecular drug [41]
GS-9857 DMYU6P5 Phase 2 Small molecular drug [42]
GSK2336805 DMI2YU1 Phase 2 NA [43]
HDV-interferon DMAX632 Phase 2 NA [44]
Hepatitis C vaccine DM1VUDL Phase 2 NA [39]
Human interferon alpha oral DMKQ3MC Phase 2 NA [45]
IFN-alpha DM4H8EZ Phase 2 NA [46]
Interferon DMYTKF5 Phase 2 NA [47]
Interferon alpha-2b DMVACTU Phase 2 NA [48]
INX-189 DMSTJ6Q Phase 2 Small molecular drug [49]
Isatoribine DMHOJ8W Phase 2 Small molecular drug [50]
ITCA-638 DMDZWPL Phase 2 NA [51]
KPE-02001003 DM9DB5L Phase 2 NA [52]
MBL-HCV1 DMJVU7Y Phase 2 NA [53]
Miravirsen DMWJMFZ Phase 2 Small molecular drug [54]
Mitoquinone DMKPZ0Q Phase 2 Small molecular drug [55]
MK-5172 DMSPWX6 Phase 2 Small molecular drug [56]
PF-4136309 DM2JZC8 Phase 2 Small molecular drug [57]
PF-4878691 DM24I0N Phase 2 NA [58]
PPI-668 DM4EHVB Phase 2 NA [59]
Q-301 DMLRBXM Phase 2 NA [60]
R-IFN-1a DMO9QB8 Phase 2 NA [61]
RG-101 DM2UGT7 Phase 2 NA [62]
SCY-635 DM1C9NQ Phase 2 Small molecular drug [63]
Setrobuvir DMTNDM2 Phase 2 Small molecular drug [22]
Tegobuvir DM6YI5T Phase 2 Small molecular drug [41]
TG-2349 DMZ571Y Phase 2 NA [64]
Vaniprevir DMCF5E0 Phase 2 Small molecular drug [56]
VX-135 DMZ3FE8 Phase 2 NA [65]
VX-222 DMO3U4W Phase 2 Small molecular drug [66]
VX-759 DMJUSM8 Phase 2 Small molecular drug [66]
ANZ-521 DM65512 Phase 1/2 NA [67]
AZD-2836 DMT2FAP Phase 1/2 NA [68]
BZF961 DMSN820 Phase 1/2 NA [69]
ChronVac-C hepatitis C DNA vaccine DMRSI1O Phase 1/2 Vaccine [70]
IDX-184 DM7U458 Phase 1/2 Small molecular drug [71]
IDX-719 DMCRVM5 Phase 1/2 NA [72]
Interferon alpha DMPYYQP Phase 1/2 NA [73]
NAHE-001 DMU6MJ1 Phase 1/2 NA [51]
PerCvax DMD6IAT Phase 1/2 NA [74]
TT-034 DM22IOE Phase 1/2 Small molecular drug [75]
A-837093 DMX0JLI Phase 1 Small molecular drug [76]
ABT-072 DMG4H9Y Phase 1 NA [77]
ABT-333 DM7TOWX Phase 1 Small molecular drug [77]
ACH-2684 DMW6X0O Phase 1 Small molecular drug [78]
AV4025 DME630T Phase 1 NA [79]
AZD-7295 DM84WXZ Phase 1 Small molecular drug [80]
Balapiravir DMAJPOX Phase 1 Small molecular drug [81]
Belerofon DM9R0VA Phase 1 NA [82]
BIT225 DMGAR9Y Phase 1 Small molecular drug [83]
BMS-824383 DMPQ5XC Phase 1 NA [30]
CC-31244 DMAYHT4 Phase 1 Small molecular drug [84]
Clemizole DM4UAPD Phase 1 Small molecular drug [85]
EDP-239 DMXW07J Phase 1 NA [86]
GS-6620 DMRDNPC Phase 1 Small molecular drug [87]
GSK-625433 DM7CIN4 Phase 1 Small molecular drug [88]
HCV vaccine DMMLMC1 Phase 1 NA [89]
HCVax DMWNFJP Phase 1 Vaccine [90]
IDX-189 DMYG3PZ Phase 1 NA [91]
IN0-8000 DM5QJN4 Phase 1 NA [92]
INO-8000 DMV5OT7 Phase 1 NA [39]
JNJ-47910382 DM1ERXJ Phase 1 NA [93]
MB-110 DMPE0KD Phase 1 Small molecular drug [94]
MBX-700 DMTXIZ1 Phase 1 NA [95]
MK-3281 DMG0Q27 Phase 1 Small molecular drug [56]
MK-6325 DMV8BI4 Phase 1 Small molecular drug [96]
PHX-1766 DMERJ6V Phase 1 NA [97]
PPI-383 DMEOJUN Phase 1 NA [98]
PPI-461 DMTOXLG Phase 1 NA [99]
PSI-938 DM5ZR4Q Phase 1 Small molecular drug [6]
RG-7348 DMFDKS7 Phase 1 NA [100]
RO-5303253 DM177J3 Phase 1 NA [101]
RO-5428029 DM27J2O Phase 1 NA [102]
Samatasvir DMAWDZZ Phase 1 Small molecular drug [103]
TMC-647055 DMYEALO Phase 1 Small molecular drug [104]
TMC649128 DMAOV7M Phase 1 NA [105]
VBY-376 DMU263R Phase 1 NA [106]
VX-500 DM8UTPJ Phase 1 NA [66]
VX-916 DMAJ2T4 Phase 1 NA [66]
XTL-6865 DML3K9N Phase 1 NA [107]
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⏷ Show the Full List of 114 Drug(s)
This Disease is Treated as An Indication in 39 Discontinued Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
HCV-796 DMPQSE4 Discontinued in Phase 2 Small molecular drug [76]
Heptazyme DM7W1QR Discontinued in Phase 2 NA [108]
IDX375 DMRPBJW Discontinued in Phase 2 NA [109]
INNO-101 DM87U7Z Discontinued in Phase 2 NA [110]
ISIS 14803 DMGZV7U Discontinued in Phase 2 Antisense drug [111]
JTK-003 DMB0V5Y Discontinued in Phase 2 NA [112]
Omega interferon DMX6GFR Discontinued in Phase 2 NA [113]
PYN-17 DMYESCR Discontinued in Phase 2 NA [114]
R7128 DM9BI3Y Discontinued in Phase 2 Small molecular drug [115]
RS-130830 DMOTANY Discontinued in Phase 2 Small molecular drug [116]
VP-50406 DMR2AXN Discontinued in Phase 2 NA [117]
GNI-103 DMY5B1B Discontinued in Phase 1/2 NA [118]
GS-9132 DMXB4T9 Discontinued in Phase 1/2 Small molecular drug [119]
HCV/MF59 DMMT5O1 Discontinued in Phase 1/2 Small molecular drug [120]
IDX-320 DMAYLS3 Discontinued in Phase 1/2 Small molecular drug [121]
R-803 DMRQPOD Discontinued in Phase 1/2 Small molecular drug [122]
ACH-2928 DMSPW3N Discontinued in Phase 1 NA [123]
AG-021541 DM1TYM4 Discontinued in Phase 1 Small molecular drug [76]
BLX-883 DMR7WYX Discontinued in Phase 1 NA [124]
HCV-371 DMI17F3 Discontinued in Phase 1 Small molecular drug [125]
JTK-109 DMUNYR7 Discontinued in Phase 1 Small molecular drug [126]
JTK-652 DMZFEY1 Discontinued in Phase 1 NA [127]
JTK-853 DM64FX9 Discontinued in Phase 1 Small molecular drug [128]
R-1479 DM9C6LN Discontinued in Phase 1 Small molecular drug [129]
R-1518 DM2J5AO Discontinued in Phase 1 NA [130]
RG-7432 DMSUV3B Discontinued in Phase 1 NA [131]
XTL-2125 DM3Y6M7 Discontinued in Phase 1 NA [76]
ANA-246 DMUEABR Terminated NA [134]
APC-6336 DMBA4DK Terminated Small molecular drug [135]
BMS-605339 DMY7ZRA Terminated NA [136]
CBH-11 DMIML1Y Terminated NA [137]
ED-001 DMB56MU Terminated NA [138]
GNI-104 DMHXRN8 Terminated Antibody [139]
GSK-2485852 DMOALVR Terminated NA [140]
Hepatitis C virus E2 protein vaccines DMOWNQ6 Terminated NA [141]
HuMax-HepC DMFVB7Z Terminated Antibody [142]
PRO-206 DM14A00 Terminated NA [143]
PSI-6130 DMWUOA8 Terminated Small molecular drug [144]
PSI-661 DM579WS Terminated NA [145]
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⏷ Show the Full List of 39 Drug(s)
This Disease is Treated as An Indication in 2 Preclinical Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
IDX136 DMRIMZL Preclinical NA [132]
NA-808 DMDE7OR Preclinical NA [133]
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This Disease is Treated as An Indication in 51 Investigative Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
1,5-Benzodiazepines series DMNVAE7 Investigative NA [146]
4SC-301 DMV336G Investigative NA [146]
A-058 DMHSPRE Investigative NA [146]
ACH-1095 DM17TPF Investigative NA [146]
ALS-2158 DMXX5XJ Investigative NA [146]
ALS-2160 DM29LFW Investigative NA [146]
Anti-HCV agent DMSLX1T Investigative NA [146]
Anti-HCV peptides DMZ0JP5 Investigative NA [146]
AVL-181 DMRQIQ3 Investigative NA [146]
BCX-5191 DMMQS6W Investigative NA [146]
BMS-633 DMBZS0A Investigative NA [146]
BMS-766 DMNMRJ1 Investigative NA [146]
C-Immune DMJP1EX Investigative NA [146]
C-Rx DMEQ0JU Investigative NA [146]
C-Vaxin DM0USNM Investigative NA [146]
CB-183872 DMU7734 Investigative NA [146]
EBP-1597 DMO3JOM Investigative NA [146]
EPB-415 DMBLSX3 Investigative NA [147]
EPB-500 DMKBUPH Investigative NA [146]
EPB-600 DMK7C30 Investigative NA [146]
EQ-317 DMMZIKN Investigative NA [146]
EQ-318 DM828E1 Investigative NA [146]
Fusopin DMAL64H Investigative NA [146]
Glycoferon DMLI5Y9 Investigative NA [146]
GX-137 DMTH9PQ Investigative NA [146]
HAp-IFN DM9K6H5 Investigative NA [148]
HCV-specific STAR fusions DMH6JOO Investigative NA [146]
HepaVaxx C DM2G6Q4 Investigative NA [146]
HS-HCV DMHL8O7 Investigative NA [146]
ID-12 DMAFO38 Investigative NA [146]
IPH-1201 DMMI6N1 Investigative NA [146]
ISG15-LNP01 DMQ8Y1B Investigative NA [146]
ITX-4520 DM63MP0 Investigative NA [146]
ITX-7650 DM4VSRB Investigative NA [146]
KIN-100 DM6A9F3 Investigative NA [146]
KPE-00001113 DMG749U Investigative NA [146]
LG-912 DM4GE7L Investigative NA [146]
Long-acting polysialic acid-interferon alpha 2b conjugate DMMBGKF Investigative NA [146]
Mu5B3 DM11N9Y Investigative NA [146]
OBP-AI1 DMLIUWO Investigative NA [146]
PPI-1301 DMJGUTD Investigative NA [146]
PSI 7851 DM5ZU1V Investigative Small molecular drug [149]
PSI-879 DM0SXSW Investigative NA [146]
PTC-725 DM471WY Investigative NA [146]
RM-4864 DMD1YFN Investigative NA [146]
SCH-10363 DM1YJP1 Investigative NA [146]
SCY-524 DMM4F9L Investigative NA [146]
SP-30 DMJZC0D Investigative NA [146]
TBI-301 DM7OSJ5 Investigative NA [146]
VBY-106 DM0RGF4 Investigative NA [146]
ZN-1014 DMWIMZL Investigative NA [146]
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⏷ Show the Full List of 51 Drug(s)

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 354 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
ADAMTS13 TTUREBK Limited Altered Expression [152]
APCS TTB7VAT Limited Biomarker [153]
APOBEC3G TTP96KH Limited Biomarker [154]
APOC3 TTXOZQ1 Limited Altered Expression [155]
APOH TT2OUI9 Limited Biomarker [156]
ARG1 TT7ZQEV Limited Genetic Variation [157]
CCL3 TT8I4WB Limited Genetic Variation [158]
CCR3 TTD3XFU Limited Genetic Variation [159]
CD14 TT6I7DC Limited Biomarker [160]
CDK5R1 TTBYM6V Limited Biomarker [161]
CES1 TTMF541 Limited Altered Expression [162]
CHUK TT1F8OQ Limited Altered Expression [163]
CR1 TTEA8OW Limited Biomarker [164]
CYP1A2 TTS1DTU Limited Biomarker [165]
EIF2AK3 TT79U1M Limited Altered Expression [166]
EIF4EBP1 TTKGEBL Limited Altered Expression [167]
FAP TTGPQ0F Limited Altered Expression [168]
FPR2 TTOJ1NF Limited Biomarker [169]
FTH1 TT975ZT Limited Biomarker [170]
IFNGR2 TT13TL0 Limited Genetic Variation [171]
IL37 TTQTX98 Limited Biomarker [172]
IRAK1 TTXAJWN Limited Biomarker [173]
ITGA2 TTSJ542 Limited Biomarker [174]
ITGAE TTH0Z37 Limited Altered Expression [175]
KLRC1 TTC4IMS Limited Biomarker [176]
KRT19 TT3JF9E Limited Biomarker [177]
LBP TTVQJLY Limited Biomarker [178]
LIPE TTLUQ8E Limited Genetic Variation [179]
LPL TTOF3WZ Limited Biomarker [180]
MAGEA3 TTWSKHD Limited Altered Expression [181]
MBTPS1 TTNSM2I Limited Biomarker [182]
MCM7 TT1RM3F Limited Altered Expression [183]
NCL TTK1V5Q Limited Biomarker [184]
NME1 TTDY8JH Limited Biomarker [185]
NR1H3 TTECBXN Limited Biomarker [186]
PKN2 TTTHO0M Limited Genetic Variation [187]
PPP2CA TTHTKNY Limited Altered Expression [188]
PSMB8 TTEAD9J Limited Biomarker [189]
RTN4 TT7GXMU Limited Genetic Variation [190]
RXRA TT6PEUO Limited Altered Expression [191]
SAA1 TTY0DN9 Limited Altered Expression [192]
SEMA4D TT5UT28 Limited Biomarker [193]
SERPINB3 TT6QLPX Limited Altered Expression [194]
SLC40A1 TT6Y1PG Limited Altered Expression [195]
SREBF2 TTRQ4AP Limited Altered Expression [196]
ST14 TTPRO7W Limited Genetic Variation [197]
TACSTD2 TTP2HE5 Limited Biomarker [198]
TIGIT TTWNL74 Limited Altered Expression [199]
TLR7 TTRJ1K4 Limited Biomarker [200]
TNFRSF10A TT5WLRX Limited Biomarker [201]
TNFSF13B TTWMIDN Limited Genetic Variation [202]
TNFSF4 TTBW580 Limited Biomarker [203]
TSLP TTHMW3T Limited Altered Expression [204]
ULK1 TT4D7MJ Limited Biomarker [205]
ASRGL1 TT4WT91 moderate Genetic Variation [206]
DCLK1 TTOHTCY moderate Altered Expression [207]
DDX58 TTVB0O3 moderate Altered Expression [208]
FCGR1A TTZK4I3 moderate Altered Expression [209]
GCG TT6Y4PN moderate Biomarker [210]
IRF1 TT4TU3L moderate Genetic Variation [211]
KIR2DS1 TTVWAGF moderate Biomarker [212]
KIR3DL2 TTQH3N0 moderate Biomarker [212]
LOXL2 TTFSUHX moderate Biomarker [213]
NDUFA13 TTRU1NG moderate Biomarker [214]
SCARB1 TTRE324 moderate Biomarker [215]
SCD TT6RIOV moderate Biomarker [216]
SMAD6 TTON5JB moderate Biomarker [217]
SRD5A2 TTT02K8 moderate Altered Expression [218]
TBX21 TTNF9PH moderate Genetic Variation [219]
TPT1 TT3PTB6 moderate Biomarker [220]
AAK1 TT0Z32T Strong Biomarker [221]
ABCB11 TTUXCAF Strong Biomarker [222]
ABCB4 TTJUXV6 Strong Genetic Variation [223]
ACAT1 TTK3C21 Strong Altered Expression [162]
ACKR1 TTKY2NS Strong Genetic Variation [224]
ACTG1 TTGAZF9 Strong Altered Expression [225]
ADH1A TT5AHZ0 Strong Altered Expression [226]
ADIPOQ TTXKA7D Strong Altered Expression [227]
AHCY TTE2KUJ Strong Genetic Variation [228]
AIF1 TT12MEP Strong Genetic Variation [229]
ALAS1 TTG1FXO Strong Altered Expression [230]
AOC3 TT7HC21 Strong Biomarker [231]
APOA2 TTGQA9W Strong Genetic Variation [232]
APOB TTN1IE2 Strong Biomarker [154]
ARF1 TT70KXY Strong Biomarker [233]
ATG7 TTLVB9Z Strong Biomarker [234]
ATP4A TTF1QVM Strong Biomarker [235]
BACH1 TT2ME4S Strong Biomarker [236]
BCL6 TTC9YX5 Strong Biomarker [237]
BLVRA TTJBPN3 Strong Altered Expression [238]
BMP6 TT07RIB Strong Biomarker [239]
BMPR2 TTGKF90 Strong Biomarker [240]
BRD7 TT07ZS1 Strong Altered Expression [241]
BTLA TTER58P Strong Biomarker [242]
C1QBP TTWTD7F Strong Genetic Variation [243]
CASP1 TTCQIBE Strong Biomarker [244]
CASP7 TTM7Y45 Strong Altered Expression [245]
CBLB TTHRAIJ Strong Biomarker [246]
CCL17 TTMPHAE Strong Altered Expression [247]
CCNA2 TTAMQ62 Strong Biomarker [248]
CCR1 TTC24WT Strong Genetic Variation [249]
CCR6 TTFDB30 Strong Biomarker [250]
CD163 TTTZ9DE Strong Genetic Variation [251]
CD19 TTW640A Strong Altered Expression [252]
CD209 TTBXIM9 Strong Biomarker [253]
CD274 TT8ZLTI Strong Altered Expression [254]
CD28 TTQ13FT Strong Biomarker [255]
CD300A TTI2YFK Strong Genetic Variation [256]
CD33 TTJVYO3 Strong Biomarker [257]
CD5 TTEGYK1 Strong Biomarker [258]
CD55 TT5Z9WY Strong Biomarker [259]
CD58 TT5KSBY Strong Biomarker [260]
CD69 TTPQE9F Strong Altered Expression [175]
CDA TTQ12RK Strong Biomarker [154]
CDK11B TT5Q79O Strong Biomarker [261]
CDKN1A TT9GUW0 Strong Biomarker [262]
CDKN2C TTBRUGA Strong Altered Expression [263]
CEBPB TTUI35N Strong Biomarker [264]
CEL TTTRNQW Strong Genetic Variation [265]
CHIT1 TTDYX6T Strong Altered Expression [266]
CLDN4 TTMTS9H Strong Biomarker [267]
CLEC4C TT7YT06 Strong Biomarker [268]
CPE TTXPWO6 Strong Biomarker [269]
CPS1 TT42M75 Strong Biomarker [270]
CRHR2 TTIY658 Strong Genetic Variation [271]
CRTC2 TTFWETR Strong Biomarker [272]
CRY1 TT5MLZR Strong Altered Expression [273]
CRY2 TTAO58M Strong Altered Expression [273]
CRYZ TTP6UO8 Strong Biomarker [274]
CSK TTX6F0Q Strong Altered Expression [275]
CSNK1A1 TTFQEMX Strong Genetic Variation [276]
CSNK1D TTH30UI Strong Biomarker [277]
CSNK1G2 TT0UZJ9 Strong Biomarker [277]
CSNK1G3 TT34L5N Strong Biomarker [277]
CTSS TTUMQVO Strong Biomarker [278]
CXCL11 TTWG0RE Strong Genetic Variation [279]
CXCL9 TTWE5PB Strong Altered Expression [280]
CXCR3 TT1UCIJ Strong Biomarker [281]
CYP24A1 TT82UI1 Strong Genetic Variation [282]
CYP2A6 TTAQ6ZW Strong Biomarker [283]
CYP2B6 TTMH124 Strong Genetic Variation [284]
CYP2C19 TTZ58XG Strong Altered Expression [285]
CYP2C9 TTR40YJ Strong Biomarker [286]
CYP2D6 TTVG215 Strong Biomarker [286]
CYP2E1 TTWVHQ5 Strong Altered Expression [287]
CYP3A4 TTWP7HQ Strong Biomarker [288]
CYP3A5 TTHS0OK Strong Biomarker [289]
DAPK3 TTERVQN Strong Biomarker [290]
DFFA TTYVQ9C Strong Altered Expression [291]
DGAT1 TT0GV3R Strong Biomarker [292]
DGAT2 TTRHEQ4 Strong Altered Expression [293]
DHCR24 TTTK0NH Strong Biomarker [294]
DNASE1 TTYWGOJ Strong Biomarker [295]
DPP4 TTDIGC1 Strong Altered Expression [168]
ELAVL1 TTPC9D0 Strong Altered Expression [296]
ENPP2 TTSCIM2 Strong Biomarker [297]
EPHA3 TTHS2LR Strong Altered Expression [298]
ERAP1 TT60XFL Strong Genetic Variation [299]
F2 TT6L509 Strong Biomarker [300]
FABP1 TTIV96N Strong Biomarker [301]
FABP2 TTS4YLO Strong Biomarker [301]
FASN TT7AOUD Strong Biomarker [302]
FCAR TTGUJAO Strong Biomarker [303]
FCGR2B TT5RWKQ Strong Altered Expression [304]
FCGR3A TTIFOC0 Strong Altered Expression [305]
FKBP5 TT0J5KQ Strong Genetic Variation [306]
FOXP3 TT1X3QF Strong Biomarker [307]
FPR1 TT5Y4EM Strong Genetic Variation [308]
G3BP1 TTG0R8Z Strong Biomarker [309]
G6PC TTBQMJ8 Strong Biomarker [272]
GADD45B TTMDW9L Strong Altered Expression [310]
GAK TT0AGBL Strong Biomarker [221]
GAP43 TTSGLN5 Strong Biomarker [311]
GGT1 TTZVT7O Strong Biomarker [312]
GOT1 TTU507L Strong Altered Expression [313]
GP6 TTTJUVZ Strong Genetic Variation [314]
GPC3 TTJTSX4 Strong Genetic Variation [315]
GPR55 TTNET8J Strong Altered Expression [316]
GPX1 TTYAHBP Strong Genetic Variation [317]
GRB2 TTEYRJ9 Strong Biomarker [318]
GSTO1 TTWO3SH Strong Genetic Variation [319]
GUCY1B1 TTLBYH1 Strong Altered Expression [320]
GUSB TTHS7CM Strong Genetic Variation [321]
GZMB TTKEPHX Strong Biomarker [322]
HDAC8 TTT6LFV Strong Altered Expression [323]
HHAT TT1VNCG Strong Biomarker [182]
HK2 TTK02H8 Strong Biomarker [324]
HLA-DQA1 TTU2I3J Strong Altered Expression [325]
HLA-G TTLKFB3 Strong Biomarker [326]
HMBS TTT0HW3 Strong Altered Expression [327]
HMGCS1 TTQF4TK Strong Altered Expression [244]
HMGCS2 TTS0EZJ Strong Altered Expression [244]
HMOX2 TTWZRL4 Strong Biomarker [238]
HNF1A TT01M3K Strong Altered Expression [328]
HNF4A TT2F3CD Strong Altered Expression [329]
HSD17B13 TTDJYZR Strong Genetic Variation [330]
HSPA8 TTMQL3K Strong Biomarker [328]
HSPB8 TTY0OJN Strong Altered Expression [331]
HTR6 TTJS8PY Strong Biomarker [332]
HTT TTIWZ0O Strong Genetic Variation [333]
ID2 TTW8A5N Strong Biomarker [334]
IDO1 TTZJYKH Strong Biomarker [335]
IFNAR1 TTSYFMA Strong Altered Expression [336]
IFNAR2 TTMQB37 Strong Altered Expression [337]
IL10RB TTJTRMK Strong Genetic Variation [338]
IL12A TTRTK6Y Strong Genetic Variation [339]
IL15 TTJFA35 Strong Biomarker [340]
IL15RA TTGN89I Strong Altered Expression [341]
IL17D TTC5LTG Strong Biomarker [342]
IL19 TT87RWS Strong Biomarker [343]
IL1R2 TT51DEV Strong Altered Expression [344]
IL1RL2 TTUS18T Strong Biomarker [345]
IL1RN TT6GSR3 Strong Genetic Variation [346]
IL20 TTNZMY2 Strong Biomarker [343]
IL21 TT9QEJ6 Strong Genetic Variation [347]
IL22 TTLDX4N Strong Biomarker [348]
IL23A TTC1GLB Strong Biomarker [349]
IL7 TT8FRMO Strong Biomarker [348]
IL7R TTAWI51 Strong Altered Expression [350]
IMPDH2 TTTB4UP Strong Biomarker [351]
IRF3 TTYR7OH Strong Biomarker [352]
IRS1 TTAJSQ0 Strong Biomarker [353]
ITGAL TT48WR6 Strong Biomarker [354]
ITPR3 TTH1769 Strong Biomarker [355]
JAK1 TT6DM01 Strong Altered Expression [356]
JUN TTS7IR5 Strong Altered Expression [357]
KHDRBS1 TTAT6C7 Strong Altered Expression [358]
KIR2DL2 TTU0P73 Strong Biomarker [359]
KIR2DS2 TTV3CFI Strong Altered Expression [360]
KLRG1 TT299E6 Strong Biomarker [361]
KLRK1 TTLRN4A Strong Biomarker [362]
LAG3 TTNVXAW Strong Biomarker [363]
LAIR1 TTSI7A8 Strong Altered Expression [364]
LAMP1 TTC214J Strong Biomarker [365]
LANCL1 TTZW8NS Strong Biomarker [366]
LAPTM4B TTEJQT0 Strong Biomarker [367]
LARP1 TTSN1YP Strong Biomarker [368]
LCK TT860QF Strong Biomarker [369]
LIPA TTS8T1M Strong Altered Expression [370]
LOX TTQHNAM Strong Biomarker [371]
LTF TTSZDQU Strong Biomarker [372]
LY75 TTG180Q Strong Genetic Variation [373]
LY9 TTZCL1U Strong Biomarker [374]
MAGEA4 TT9EQUY Strong Biomarker [375]
MAP3K11 TTETX6Q Strong Biomarker [376]
MAPKAP1 TTWDKCL Strong Biomarker [377]
MAPKAPK3 TTFS4VU Strong Genetic Variation [378]
MAPKAPK5 TT3UJ7Z Strong Altered Expression [379]
MBP TT2RY5P Strong Biomarker [380]
MCM6 TTQGKSD Strong Biomarker [381]
MFGE8 TT1GLAJ Strong Biomarker [382]
MS4A1 TTUE541 Strong Altered Expression [325]
MTTP TTUS1RD Strong Genetic Variation [383]
NAAA TTMN4HY Strong Biomarker [384]
NCAM1 TTVXPHT Strong Altered Expression [385]
NCR1 TTQNRJM Strong Genetic Variation [386]
NEK2 TT3VZ24 Strong Biomarker [387]
NLRX1 TTKT026 Strong Biomarker [388]
NOTCH4 TTXDIK2 Strong Genetic Variation [389]
NOX4 TTQRBSJ Strong Altered Expression [390]
NPC1L1 TTPD1CN Strong Genetic Variation [391]
NR0B2 TT25A9Q Strong Biomarker [392]
NRP2 TTRXUVC Strong Genetic Variation [393]
NTSR1 TTTUMEP Strong Biomarker [394]
NUAK2 TTHVOTQ Strong Biomarker [395]
OPRM1 TTKWM86 Strong Biomarker [396]
OXTR TTSCIUP Strong Genetic Variation [157]
P2RX4 TT1NLOA Strong Biomarker [397]
PAK2 TT279WO Strong Biomarker [261]
PDCD1LG2 TTW14O3 Strong Biomarker [398]
PDZK1 TTDTBLM Strong Biomarker [399]
PF4 TTSG7Q5 Strong Altered Expression [400]
PHGDH TT8DRCK Strong Biomarker [169]
PI4KA TTCUS9F Strong Biomarker [401]
PI4KB TTNPL3B Strong Biomarker [402]
PIM2 TT69J2Z Strong Biomarker [403]
PLIN1 TTIV27N Strong Biomarker [404]
PMEL TT8MK59 Strong Altered Expression [405]
PPARA TTJ584C Strong Biomarker [406]
PPIA TTL2ADK Strong Biomarker [407]
PPIB TT6ZFQ4 Strong Biomarker [408]
PPM1A TTLA7IX Strong Altered Expression [409]
PREP TTNGKET Strong Biomarker [410]
PROC TTZUXYS Strong Altered Expression [411]
PRSS1 TT2WR1T Strong Biomarker [412]
PSMD10 TT2H4LN Strong Genetic Variation [319]
PTBP1 TTWMX0U Strong Biomarker [413]
PTPN7 TT2C1DT Strong Altered Expression [414]
PTPRC TTUS45N Strong Biomarker [415]
RAB7A TTF6WAQ Strong Biomarker [416]
RACK1 TTJ10AL Strong Biomarker [417]
RECK TTRZBW7 Strong Genetic Variation [418]
RNF7 TTODWGT Strong Genetic Variation [419]
RORA TT1TYN7 Strong Altered Expression [273]
RORC TTGV6LY Strong Genetic Variation [420]
RPS6KA3 TTUM2ZR Strong Biomarker [421]
RRM2 TT1S4LJ Strong Altered Expression [422]
S100A9 TT0TMQG Strong Altered Expression [423]
SDC1 TTYDSVG Strong Biomarker [424]
SDC2 TT5H2F0 Strong Biomarker [425]
SETD7 TTJ0FSU Strong Biomarker [426]
SIGMAR1 TT5TPI6 Strong Biomarker [427]
SLC10A1 TTWZRY5 Strong Genetic Variation [428]
SLC12A3 TTP362L Strong Genetic Variation [429]
SLC22A1 TTM5Q4V Strong Biomarker [430]
SLC25A1 TTTD730 Strong Genetic Variation [431]
SLC27A4 TT20AYF Strong Biomarker [169]
SLC28A2 TTVP9IQ Strong Biomarker [432]
SLC29A1 TTLXAKE Strong Genetic Variation [433]
SLC30A8 TTXIGT7 Strong Genetic Variation [434]
SLC3A2 TT5CZSM Strong Biomarker [435]
SLC6A12 TTQBMPI Strong Altered Expression [436]
SLCO1A2 TTUGD21 Strong Genetic Variation [437]
SLCO2B1 TTDL3UZ Strong Genetic Variation [222]
SMAD1 TT9GR53 Strong Altered Expression [438]
SMAD7 TT0J32Z Strong Biomarker [439]
SMYD3 TTKLJYX Strong Biomarker [440]
SQSTM1 TTOT2RY Strong Altered Expression [358]
SRC TT6PKBN Strong Biomarker [441]
SREBF1 TTER0UB Strong Altered Expression [442]
STAT1 TTN7R6K Strong Biomarker [443]
TAP1 TT7JZI8 Strong Altered Expression [444]
TDP1 TT64IHJ Strong Biomarker [445]
TERF2 TT5XSLT Strong Altered Expression [446]
TGFBR1 TTP4520 Strong Biomarker [447]
THPO TTCG5PE Strong Biomarker [448]
TICAM1 TT2GQT6 Strong Biomarker [449]
TLR2 TTY7ZHS Strong Genetic Variation [450]
TLR3 TTD24Y0 Strong Biomarker [451]
TLR6 TTWRI8V Strong Biomarker [452]
TLR8 TT8CWFK Strong Genetic Variation [453]
TLR9 TTSHG0T Strong Altered Expression [454]
TM6SF2 TTE1OHM Strong Genetic Variation [455]
TMSB4X TTMVAIU Strong Altered Expression [456]
TNFRSF21 TT8UA0T Strong Altered Expression [457]
TNFRSF25 TTDV6BQ Strong Biomarker [458]
TNK2 TTIET93 Strong Biomarker [459]
TOP1 TTGTQHC Strong Biomarker [460]
TPX2 TT0PHL4 Strong Altered Expression [405]
TRAF6 TTCDR6M Strong Biomarker [461]
TREM1 TTHZQP0 Strong Altered Expression [462]
TRIM27 TTTO3QN Strong Biomarker [352]
TRPC5 TT32NQ1 Strong Biomarker [463]
UBC TTBP3XA Strong Altered Expression [464]
UBE3A TTUZX6V Strong Biomarker [465]
WAS TTE8T73 Strong Biomarker [466]
WRN TT2H5WQ Strong Altered Expression [467]
XRCC5 TTCB9KW Strong Biomarker [468]
ZAP70 TTUMHT8 Strong Biomarker [469]
CTLA4 TTI2S1D Definitive Genetic Variation [470]
GAPDH TTUGSWA Definitive Biomarker [260]
MERTK TTO7LKR Definitive Genetic Variation [211]
PIK3CB TT9H4P3 Definitive Biomarker [471]
RNASEL TT7V0K4 Definitive Altered Expression [405]
------------------------------------------------------------------------------------
⏷ Show the Full List of 354 DTT(s)
This Disease Is Related to 13 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
SLC26A3 DTN1FMD Limited Biomarker [472]
ABCC6 DT582KR Strong Biomarker [473]
ABCD1 DTKM9DZ Strong Biomarker [474]
ATP12A DT5NLZA Strong Biomarker [235]
SLC25A20 DTQOUM4 Strong Genetic Variation [475]
SLC27A2 DTXK9WA Strong Altered Expression [320]
SLC28A3 DT4YL5R Strong Biomarker [476]
SLC29A2 DTW78DQ Strong Genetic Variation [477]
SLC2A2 DTUJPOL Strong Biomarker [328]
SLC35A2 DT0567K Strong Genetic Variation [478]
SLC4A1 DTB0Q3P Strong Genetic Variation [479]
SLC7A9 DTP7AEQ Strong Genetic Variation [480]
SLCO6A1 DTIFXNS Strong Biomarker [481]
------------------------------------------------------------------------------------
⏷ Show the Full List of 13 DTP(s)
This Disease Is Related to 20 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
AKR1B10 DEP6GT1 Limited Altered Expression [482]
DHCR7 DEL7GFA Limited Genetic Variation [483]
HINT1 DEWJATF Limited Biomarker [484]
TPMT DEFQ8VO Limited Genetic Variation [485]
NAT10 DEZV4AP moderate Genetic Variation [206]
UGT1A7 DEZO4N3 moderate Genetic Variation [486]
ABO DESIA7R Strong Biomarker [487]
ADH4 DEOCWU3 Strong Biomarker [226]
CES2 DETHCPD Strong Altered Expression [488]
CYP27A1 DEBS639 Strong Genetic Variation [489]
CYP2C18 DEZMWRE Strong Altered Expression [285]
CYP4F3 DEFCMPI Strong Altered Expression [285]
EPHX1 DELB4KP Strong Genetic Variation [490]
MT2A DEFKGT7 Strong Biomarker [491]
PCYT1A DEQYXD4 Strong Altered Expression [492]
PER1 DE9HF0I Strong Altered Expression [273]
SMOX DEOH5V3 Strong Altered Expression [493]
SULT2A1 DE0P6LK Strong Biomarker [469]
THOP1 DE95LJC Strong Altered Expression [494]
UBASH3B DE10BJ5 Strong Biomarker [495]
------------------------------------------------------------------------------------
⏷ Show the Full List of 20 DME(s)
This Disease Is Related to 592 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
AGA OTNWT1WB Limited Biomarker [496]
ARF4 OT3GMDHA Limited Biomarker [497]
ARHGAP24 OTCQCEZS Limited Biomarker [263]
ARHGEF7 OT9BPJCL Limited Biomarker [498]
ATF2 OTNIZPEA Limited Biomarker [499]
ATG14 OTPZDKI0 Limited Biomarker [417]
ATG16L1 OTEOYC5D Limited Biomarker [500]
B3GAT1 OTXFP98E Limited Biomarker [501]
CALM2 OTNYA92F Limited Biomarker [502]
CAMKMT OTLJBRUW Limited Biomarker [502]
CBFA2T2 OTNOIB23 Limited Biomarker [498]
CCL14 OT8QETQU Limited Genetic Variation [249]
CCL8 OTCTWYN8 Limited Altered Expression [503]
CCNG1 OT17IA9L Limited Altered Expression [504]
CD82 OTH8MC64 Limited Biomarker [505]
CHCHD2 OTL5PA3Y Limited Biomarker [506]
CISH OT8T5NYL Limited Biomarker [507]
CKB OTUCKOTT Limited Altered Expression [508]
CLIP1 OTTGAEJE Limited Biomarker [509]
CLIP2 OTSCIQIY Limited Biomarker [509]
CREB3 OT9617UO Limited Altered Expression [510]
CREM OTJIJ5AL Limited Biomarker [511]
CYP2D7 OTYJTL3S Limited Genetic Variation [512]
DCAF1 OT3ZDVOE Limited Biomarker [513]
DCTN3 OTQOSUES Limited Biomarker [514]
DDB1 OTTR2L3Z Limited Biomarker [513]
DDX56 OTGURA53 Limited Genetic Variation [515]
DHX58 OT19BYB1 Limited Biomarker [516]
DYNC1H1 OTD1KRKO Limited Biomarker [514]
EFNA4 OTITKZQH Limited Biomarker [517]
EIF2A OTWXELQP Limited Biomarker [518]
EIF4G1 OT2CF1E6 Limited Biomarker [518]
EIF5B OTZTT22W Limited Biomarker [519]
ETFA OTXX61VZ Limited Biomarker [520]
EXT1 OTRPALJK Limited Biomarker [521]
FBN2 OT3KYJQL Limited Biomarker [522]
FLNB OTPCOYL6 Limited Genetic Variation [523]
FOXA2 OTJOCVOY Limited Biomarker [524]
GC OTWS63BY Limited Genetic Variation [525]
GPR158 OTYOC1RQ Limited Genetic Variation [526]
GPX2 OTXI2NTI Limited Biomarker [527]
HERC5 OTZ5PR39 Limited Biomarker [528]
HFM1 OTHV3EFE Limited Genetic Variation [529]
HJV OT4235J2 Limited Altered Expression [530]
HLA-DOB OTKADDUB Limited Genetic Variation [531]
HPCAL1 OTOBBFRD Limited Altered Expression [532]
IFNA6 OTX5EQ87 Limited Biomarker [533]
IGF2BP1 OT9G360P Limited Biomarker [534]
IL10RA OTOX3D1D Limited Genetic Variation [535]
ILF3 OTKMZ5K5 Limited Biomarker [536]
IRF9 OTK4MYQJ Limited Biomarker [537]
ITGA2B OT4Y17PY Limited Genetic Variation [174]
ITGAX OTOGIMHE Limited Altered Expression [325]
JUNB OTG2JXV5 Limited Altered Expression [538]
JUND OTNKACJD Limited Altered Expression [538]
KIDINS220 OTLBH2MA Limited Genetic Variation [539]
KIR2DL5B OTSV0JL9 Limited Altered Expression [360]
KLF6 OTQY9S7F Limited Biomarker [540]
KLRB1 OTQ2959Y Limited Biomarker [541]
KLRD1 OTMYLOV4 Limited Biomarker [153]
KRIT1 OT58AP1I Limited Biomarker [502]
KRT7 OTLT3JFN Limited Biomarker [542]
LBR OT1HG3HG Limited Biomarker [543]
LIG4 OT40DNXU Limited Biomarker [544]
MARCHF1 OTI2EYO6 Limited Genetic Variation [545]
MCM2 OTGGORIQ Limited Altered Expression [183]
MICB OTS2DVDW Limited Genetic Variation [480]
MNAT1 OTXLOYCB Limited Biomarker [546]
MTG1 OTC9U1LI Limited Biomarker [547]
MX1 OT6X8G5T Limited Genetic Variation [548]
NANOG OTUEY1FM Limited Biomarker [549]
NCR3 OT20M764 Limited Biomarker [550]
NEIL2 OTV6JEON Limited Genetic Variation [551]
NHS OTKE8QAT Limited Biomarker [552]
NPC1 OTRIPICX Limited Biomarker [553]
NT5C1A OTS7UF36 Limited Biomarker [554]
NTPCR OTTRT6Z9 Limited Biomarker [555]
NXF1 OTEFHXG6 Limited Genetic Variation [523]
OASL OTZ05YRP Limited Altered Expression [556]
PCBD1 OTDSRUD5 Limited Biomarker [557]
PHB2 OTCAX3AW Limited Biomarker [514]
PIAS1 OTZVAHZI Limited Biomarker [558]
PIK3R2 OTZSUQK5 Limited Biomarker [498]
PMPCA OT5X1G9Q Limited Biomarker [559]
PPP1R12C OT9Q86JO Limited Biomarker [498]
PPP1R13B OTC88VQO Limited Biomarker [498]
RACGAP1 OTQE8IEH Limited Biomarker [248]
RMDN1 OTE1NB6U Limited Biomarker [560]
RMDN2 OTK5WSFI Limited Biomarker [560]
RMDN3 OTKO7AUM Limited Biomarker [560]
RNH1 OT6EC79B Limited Biomarker [561]
RTN1 OTCX1SMK Limited Biomarker [562]
SARDH OTQ49Q27 Limited Biomarker [563]
SELENOP OT02B8IR Limited Altered Expression [208]
SET OTGYYQJO Limited Biomarker [564]
SHBG OTPWU5IW Limited Biomarker [565]
SPINT1 OT1CLR5L Limited Genetic Variation [197]
SRL OT7IEBWZ Limited Biomarker [563]
STAT4 OTAK3VFR Limited Genetic Variation [566]
SUMO1 OTJFD4P5 Limited Biomarker [567]
SYBU OT3FQV7N Limited Biomarker [560]
TFF3 OTJJDRTU Limited Altered Expression [568]
TGFBRAP1 OT80QNR5 Limited Altered Expression [532]
TJP1 OTBDCUPK Limited Biomarker [569]
TP73 OT0LUO47 Limited Biomarker [263]
TRIM22 OTJBLG5R Limited Biomarker [570]
ALPP OTZU4G9W moderate Genetic Variation [206]
ATRNL1 OTY5JUX2 moderate Genetic Variation [206]
CCL27 OTUZYC61 moderate Genetic Variation [206]
DCC OT2C1SHW moderate Biomarker [571]
MIP OTEBLU3E moderate Genetic Variation [572]
NRDC OTWBBCXO moderate Biomarker [573]
PDLIM3 OTVXQC81 moderate Genetic Variation [206]
SLPI OTUNFUU8 moderate Genetic Variation [206]
SMG1 OTTS3SXE moderate Biomarker [297]
TFR2 OTMYCCEO moderate Genetic Variation [574]
ACACA OT5CQPZY Strong Biomarker [575]
ACAT2 OTZ092ZJ Strong Altered Expression [162]
ACD OTC54EPO Strong Biomarker [576]
ACSL3 OT3MWER1 Strong Biomarker [577]
ACTA1 OTOVGLPG Strong Biomarker [578]
ADI1 OT8IOD03 Strong Biomarker [579]
AFM OTPOR8IO Strong Biomarker [580]
AGFG1 OTI8ZKC4 Strong Biomarker [581]
AGL OTWBM7WY Strong Biomarker [582]
AGO1 OTD3R434 Strong Biomarker [583]
AGO2 OT4JY32Q Strong Biomarker [584]
AIMP1 OTTA5C3U Strong Biomarker [481]
ALDH7A1 OTV57BZD Strong Biomarker [585]
ALG10 OTM1ATVR Strong Altered Expression [320]
AMPD1 OTU17BCI Strong Biomarker [586]
ANXA6 OT9KIQ0Y Strong Biomarker [495]
AP1S3 OTPCMV24 Strong Biomarker [587]
AP2M1 OTQCOSFN Strong Biomarker [588]
APCDD1 OTV9AD0L Strong Biomarker [589]
APOBEC3B OTHLNI51 Strong Biomarker [154]
APOC1 OTA58CED Strong Biomarker [590]
APOC2 OTLINYIQ Strong Altered Expression [155]
APOC4 OTE8ZUXY Strong Altered Expression [591]
APOL3 OT95SQHR Strong Altered Expression [327]
APOM OTI3FQQC Strong Biomarker [592]
ARF5 OTZO9S3U Strong Biomarker [497]
ARHGAP26 OTNGQU7A Strong Genetic Variation [190]
ARHGEF5 OTUVGFT9 Strong Biomarker [593]
ARHGEF9 OTB1FLIW Strong Biomarker [594]
ARID2 OTIRJXWM Strong Genetic Variation [595]
ARMH1 OTTJC0D6 Strong Biomarker [366]
ASCC2 OT3B204T Strong Altered Expression [405]
ATF7IP OTU6ZA7F Strong Biomarker [596]
ATG5 OT4T5SMS Strong Biomarker [597]
ATP2C1 OTQN51T3 Strong Altered Expression [598]
ATP6V1G2 OTM1DSKL Strong Genetic Variation [480]
AZIN1 OTX5W77I Strong Biomarker [599]
BCAP31 OTKSACR4 Strong Genetic Variation [319]
BCCIP OTFFKG79 Strong Biomarker [220]
BCL2L12 OTS6IFZY Strong Biomarker [600]
BCL9 OTRBIPR4 Strong Biomarker [403]
BMP3 OTCTI0UW Strong Biomarker [403]
BMPER OTBYON4H Strong Biomarker [601]
BMS1 OTEGQ8ZO Strong Biomarker [575]
BOC OTXBCY9W Strong Genetic Variation [602]
BTG3 OT9ANHVT Strong Biomarker [603]
BTN1A1 OTSQWC36 Strong Genetic Variation [604]
BTN3A2 OT3DIBU3 Strong Genetic Variation [604]
BTN3A3 OTKMSJRA Strong Genetic Variation [604]
CABIN1 OT4G5CIK Strong Altered Expression [554]
CAPN5 OTQ8QM7K Strong Biomarker [246]
CARD16 OT4NUHWB Strong Biomarker [233]
CARD8 OTXXZYWU Strong Biomarker [605]
CAV3 OTWSFDB4 Strong Genetic Variation [157]
CAVIN1 OTFO915U Strong Biomarker [606]
CAVIN2 OTFHHDRU Strong Altered Expression [606]
CAVIN3 OTOLBK79 Strong Altered Expression [606]
CCL3L1 OTQXCYB1 Strong Biomarker [607]
CD1C OT4XINUJ Strong Biomarker [608]
CD1D OT3ROU4J Strong Biomarker [609]
CD200R1 OT65Q9M6 Strong Altered Expression [364]
CD226 OT4UG0KB Strong Biomarker [610]
CD244 OTSMR85N Strong Biomarker [153]
CD2AP OTC76KQM Strong Biomarker [353]
CD300LF OTQWJGSR Strong Genetic Variation [256]
CD63 OT2UGZA9 Strong Biomarker [611]
CD68 OTOYEY3J Strong Altered Expression [462]
CD8A OTDWQJXK Strong Genetic Variation [243]
CD8B OTMZ1T7J Strong Altered Expression [325]
CD99 OTPUZ5DE Strong Biomarker [612]
CDCA5 OTZLCQ5U Strong Altered Expression [366]
CDK2AP2 OTR99SJ8 Strong Altered Expression [423]
CDKN2D OT2TTZPZ Strong Biomarker [613]
CDSN OTQW4HV6 Strong Biomarker [614]
CELF1 OT6JQ5RS Strong Genetic Variation [615]
CH25H OT9S2BSW Strong Altered Expression [286]
CHI3L1 OT2Z7VJH Strong Genetic Variation [616]
CINP OTZ31XOT Strong Biomarker [617]
CIRBP OTXWTPBL Strong Biomarker [618]
CLCN5 OT9YXZSO Strong Biomarker [619]
CLDN7 OTNE0XHQ Strong Biomarker [620]
CLEC4M OT2WUIIP Strong Biomarker [621]
CLTC OTBFASMA Strong Genetic Variation [479]
CMC2 OTRYIO1J Strong Genetic Variation [622]
CNBP OTTGM9NK Strong Biomarker [623]
CNOT1 OTTEU05F Strong Biomarker [624]
COP1 OT6J2K12 Strong Biomarker [233]
COX8A OTU0NR39 Strong Genetic Variation [625]
CPQ OTTNZNLD Strong Altered Expression [626]
CPT1A OTI862QH Strong Altered Expression [302]
CPT2 OTIN6G20 Strong Altered Expression [302]
CRABP1 OTISDG5X Strong Biomarker [627]
CRABP2 OTY01V9G Strong Biomarker [627]
CREB3L3 OTDMU3GP Strong Biomarker [628]
CRISP3 OTBSWMPL Strong Biomarker [629]
CRLF3 OTT9TMXN Strong Biomarker [537]
CRLS1 OT7XNL0K Strong Biomarker [421]
CRYGD OTW29JC4 Strong Biomarker [630]
CTNNBL1 OT6KLHPA Strong Biomarker [631]
CUX1 OTU1LCNJ Strong Altered Expression [405]
CYBA OT16N9ZO Strong Genetic Variation [632]
CYP2A7 OTRJ3P2Z Strong Biomarker [633]
DCDC2 OTSUFH1H Strong Biomarker [634]
DCTN4 OTM7C943 Strong Altered Expression [358]
DDOST OT39PDMS Strong Biomarker [635]
DDX18 OTKB9C3S Strong Genetic Variation [455]
DDX19A OTBTDR44 Strong Genetic Variation [636]
DDX39A OT0Z6E1K Strong Genetic Variation [480]
DDX39B OTEVCFVU Strong Genetic Variation [480]
DDX3X OTDO4TRX Strong Altered Expression [637]
DDX41 OT6KEIHP Strong Biomarker [638]
DDX46 OTB2X9TO Strong Genetic Variation [636]
DDX6 OTKWXVDY Strong Biomarker [515]
DEPDC5 OTE70JLY Strong Genetic Variation [639]
DHX16 OTW8KZAU Strong Genetic Variation [636]
DHX9 OT5AAOQI Strong Biomarker [534]
DIAPH2 OTBEYFEZ Strong Biomarker [640]
DNAJC3 OT7ROIJF Strong Biomarker [261]
DNAJC5B OTHDMM7O Strong Biomarker [331]
DNALI1 OTTB3L8N Strong Genetic Variation [319]
DUSP11 OTU6C41M Strong Biomarker [619]
DUSP6 OT4H6RKW Strong Altered Expression [641]
DYM OTQ670WI Strong Biomarker [642]
EBNA1BP2 OTBRVMZH Strong Biomarker [366]
EDEM1 OTWHN69S Strong Biomarker [643]
EDEM3 OT4GJX9R Strong Biomarker [643]
EFL1 OTMEXJZA Strong Biomarker [644]
EIF2D OTE109AY Strong Biomarker [518]
EIF3A OTFABY9G Strong Biomarker [645]
EIF6 OTEXMUED Strong Altered Expression [646]
ELF1 OTV5LKIA Strong Biomarker [644]
EMB OT67E3Q1 Strong Genetic Variation [647]
ENAM OTK8PU0T Strong Biomarker [648]
ERC1 OTYBGGNO Strong Biomarker [649]
ERLIN1 OTUOOODY Strong Biomarker [650]
ERVW-1 OTWV8DXJ Strong Genetic Variation [651]
FAM107B OT5RG4J0 Strong Genetic Variation [652]
FAM72A OTBZYSR3 Strong Biomarker [653]
FAM72B OT6AOG64 Strong Biomarker [653]
FARP2 OTNRQIMK Strong Biomarker [654]
FBP1 OTQBANEP Strong Biomarker [220]
FBXL2 OT5EZ7PD Strong Biomarker [355]
FCGR2C OTNLMNYB Strong Altered Expression [304]
FCGR3B OTSLSPZG Strong Altered Expression [305]
FCN2 OTTHJBKZ Strong Biomarker [655]
FCRL4 OT3DVTRV Strong Biomarker [656]
FEV OTYEC4IR Strong Biomarker [657]
FKBP8 OT8RPSOC Strong Biomarker [658]
FLVCR1 OT9XCFOC Strong Altered Expression [230]
FUBP1 OT77SC9N Strong Biomarker [220]
FUNDC2 OTY3TQM5 Strong Biomarker [659]
FUT1 OTODG57A Strong Altered Expression [660]
FUT8 OTJJCVG1 Strong Biomarker [661]
GABARAP OTAQUX6E Strong Biomarker [662]
GALNT8 OT05BKVP Strong Genetic Variation [663]
GBF1 OTY1KEHY Strong Genetic Variation [664]
GBP1 OTUM7RPJ Strong Altered Expression [665]
GCHFR OTEOT8GI Strong Altered Expression [366]
GCKR OTSIWXGG Strong Altered Expression [320]
GDE1 OTU6FSBF Strong Biomarker [439]
GFER OTVK43OK Strong Altered Expression [666]
GFRA1 OT3WBVYB Strong Biomarker [667]
GGPS1 OTVEHG28 Strong Altered Expression [668]
GLT8D2 OT4VS9YY Strong Genetic Variation [419]
GLTP OTM78ZFI Strong Biomarker [669]
GNB3 OTA6HYBA Strong Genetic Variation [670]
GOLM1 OTOZSV6O Strong Biomarker [671]
GOLPH3 OTDLGYM3 Strong Biomarker [461]
GOSR1 OTX8TMVU Strong Genetic Variation [319]
GOT2 OT6XBWN0 Strong Altered Expression [313]
GP2 OTB6TMGY Strong Genetic Variation [672]
GPR161 OT80FYA3 Strong Biomarker [673]
GSTK1 OTDNGWAF Strong Biomarker [481]
GTF2A1L OTDQHVAI Strong Biomarker [580]
GTF2H1 OTCRXC6B Strong Altered Expression [358]
GZMH OTG3259L Strong Altered Expression [674]
H1-5 OTAN7RD9 Strong Biomarker [675]
HABP2 OTAUIPW0 Strong Genetic Variation [676]
HADHA OTO557N2 Strong Biomarker [558]
HARS1 OTHOEOTS Strong Biomarker [677]
HAVCR2 OTOL603T Strong Biomarker [678]
HBP1 OTDPGGDV Strong Altered Expression [679]
HCP5 OTV0YRI8 Strong Genetic Variation [680]
HDDC2 OTSO0JP4 Strong Genetic Variation [681]
HGS OTCYYCAC Strong Biomarker [677]
HILPDA OTEID3ZM Strong Biomarker [682]
HLA-DPA1 OT7OG7Y2 Strong Biomarker [683]
HLA-DPB1 OTW8JHU2 Strong Genetic Variation [684]
HLA-DQA2 OT1DH0N9 Strong Genetic Variation [685]
HLA-DRB3 OT5PM9N7 Strong Biomarker [686]
HLA-DRB4 OTNXIHQU Strong Genetic Variation [687]
HLA-E OTX1CTFB Strong Biomarker [688]
HLA-F OT76CM19 Strong Biomarker [689]
HLF OTTRK9XN Strong Altered Expression [372]
HM13 OTGEO1LP Strong Biomarker [690]
HNRNPC OT47AK4C Strong Biomarker [534]
HNRNPD OT5UO1FA Strong Altered Expression [691]
HNRNPDL OTB3BFCV Strong Biomarker [534]
HNRNPK OTNPRM8U Strong Biomarker [692]
HNRNPL OT0DJX74 Strong Biomarker [534]
HPSE2 OTGEPP8V Strong Genetic Variation [174]
HSF4 OT1UX9SK Strong Biomarker [693]
ICAM3 OTTZ5A5D Strong Genetic Variation [694]
IER3 OTZJI5FZ Strong Biomarker [695]
IFI44 OTOKSZVA Strong Biomarker [696]
IFI6 OTWOOAM4 Strong Biomarker [697]
IFIT1 OTXOQDSG Strong Biomarker [698]
IFIT5 OTYTSO77 Strong Biomarker [261]
IFITM1 OTECO1G8 Strong Altered Expression [699]
IFNA4 OTII5O0G Strong Biomarker [700]
IFNE OTXO5MHZ Strong Genetic Variation [701]
IFNGR1 OTCTQBWW Strong Biomarker [702]
IFNLR1 OTWWWK45 Strong Altered Expression [703]
IFT122 OTSK3OAD Strong Biomarker [704]
IGFBP4 OT2HZRBD Strong Genetic Variation [393]
IGSF6 OT5TUH02 Strong Biomarker [705]
IGSF8 OTU22IKI Strong Biomarker [706]
IL18BP OTW0LRYZ Strong Biomarker [707]
IL1RAPL2 OTP7IOJO Strong Altered Expression [344]
IL27 OTIS3OF8 Strong Biomarker [342]
IL36RN OT5CO95A Strong Biomarker [345]
ILF2 OTWWVM9X Strong Biomarker [536]
IMMT OTBDSLE7 Strong Biomarker [708]
IMPACT OTQ923OB Strong Biomarker [709]
ING2 OT6H0EWF Strong Genetic Variation [243]
INPPL1 OTCDAVBQ Strong Altered Expression [710]
INSRR OT3F75WA Strong Biomarker [711]
IRAK2 OT6Y1QZN Strong Genetic Variation [712]
IRF2 OTAZRUW3 Strong Altered Expression [341]
IRF5 OT8SIIAP Strong Biomarker [713]
IRF7 OTC1A2PQ Strong Altered Expression [714]
IRGM OTKD3O5Z Strong Biomarker [715]
ITPRIP OT9YEJXS Strong Biomarker [716]
IVNS1ABP OTYHL4I7 Strong Genetic Variation [717]
JPT1 OT6CRZEU Strong Biomarker [718]
KAT8 OT5LPQTR Strong Altered Expression [320]
KIAA1549L OT80HUVY Strong Genetic Variation [157]
KIF1B OTI1XQTO Strong Genetic Variation [719]
KIR2DL5A OT09FZE1 Strong Genetic Variation [720]
KIR2DS3 OT3PSLDL Strong Biomarker [721]
KIR2DS4 OT00N6UJ Strong Biomarker [722]
KIR3DS1 OTJWIO4T Strong Biomarker [723]
KLHL1 OTAX6SAD Strong Altered Expression [724]
KLK10 OTD573EL Strong Posttranslational Modification [725]
KLRC2 OTT4N86S Strong Altered Expression [212]
KPNA1 OTEMVAJ6 Strong Biomarker [726]
KRT14 OTUVZ1DW Strong Genetic Variation [727]
KRT18 OTVLQFIP Strong Biomarker [728]
KRT20 OT4RB40L Strong Altered Expression [325]
LAMP3 OTN0XL3W Strong Altered Expression [328]
LAMTOR2 OTHEDISB Strong Altered Expression [423]
LDLRAP1 OT6QTX7R Strong Genetic Variation [729]
LGALS3BP OT9AGQKH Strong Altered Expression [730]
LGALS4 OTKQCG0H Strong Genetic Variation [731]
LGALS9 OT7MF91K Strong Biomarker [732]
LIX1 OT1CPNCC Strong Biomarker [733]
LMO1 OTB59SKB Strong Biomarker [734]
LPCAT1 OTCV7AGV Strong Altered Expression [735]
LSAMP OTYXVQX2 Strong Altered Expression [328]
LTBP2 OTS88GSD Strong Altered Expression [736]
LUM OTSRC874 Strong Altered Expression [737]
MAP1LC3A OTPMGIU4 Strong Biomarker [738]
MAP1LC3B OTUYHB84 Strong Altered Expression [739]
MARCHF2 OTADQ0OA Strong Biomarker [740]
MASP1 OTWWCNZP Strong Altered Expression [412]
MATK OTVOJJLJ Strong Biomarker [741]
MCF2L OTEURA8N Strong Biomarker [635]
MCM3 OTOOHQPM Strong Biomarker [742]
MED19 OTT9RT5N Strong Altered Expression [743]
MED9 OT59OKEJ Strong Biomarker [682]
MFAP1 OTZN4FT3 Strong Altered Expression [744]
MICA OTPEIEAR Strong Genetic Variation [745]
MIXL1 OT584VOQ Strong Genetic Variation [746]
MPG OTAHW80B Strong Genetic Variation [747]
MPIG6B OTVNKQWA Strong Biomarker [748]
MR1 OTZU3XX7 Strong Genetic Variation [745]
MRPL28 OT4LUTZU Strong Biomarker [749]
MRPS18B OT1K9PFX Strong Altered Expression [750]
MT1B OTUA4FFH Strong Genetic Variation [383]
MXD1 OTS5CTHX Strong Biomarker [586]
MYO18A OT2YPT7O Strong Posttranslational Modification [751]
NAP1L1 OTI7WBZV Strong Biomarker [752]
NCAM2 OT8LBJN8 Strong Genetic Variation [190]
NCKIPSD OT24UORN Strong Genetic Variation [753]
NCOA7 OT2CNBOG Strong Biomarker [754]
NDC80 OTS7D306 Strong Biomarker [248]
NEIL1 OTHBU5DJ Strong Biomarker [755]
NELFE OTL4E94L Strong Altered Expression [756]
NEURL3 OTA3ALQO Strong Biomarker [757]
NFKBIB OTY1ZJXH Strong Altered Expression [758]
NFKBIE OTLAYEL9 Strong Genetic Variation [759]
NFKBIL1 OTYFTPS0 Strong Genetic Variation [480]
NR1D2 OT9CVF41 Strong Biomarker [760]
NSUN2 OTZCNM33 Strong Biomarker [682]
NUMB OTMB586Q Strong Posttranslational Modification [761]
NUP62 OTMN63DH Strong Altered Expression [358]
NXT1 OT0VO6AY Strong Biomarker [749]
OAS1 OT8ZLOCY Strong Altered Expression [665]
OAS2 OT64CCTM Strong Altered Expression [762]
OAS3 OT6E5FYS Strong Biomarker [405]
ODR4 OTGC56W3 Strong Biomarker [734]
OGT OT1Z1ZXE Strong Altered Expression [763]
OPTN OT2UXWH9 Strong Biomarker [764]
OR10A4 OTYYB8SY Strong Genetic Variation [765]
OSBP2 OTDGLB4J Strong Altered Expression [766]
PACSIN2 OTC2R00C Strong Altered Expression [767]
PAK3 OT80M3BV Strong Biomarker [473]
PCBP2 OTXCN9CG Strong Biomarker [388]
PCK2 OTJ8LX4N Strong Altered Expression [768]
PCLAF OTMVIOUU Strong Altered Expression [769]
PDIA3 OTHPQ0Q3 Strong Biomarker [261]
PDIK1L OTISF4KG Strong Altered Expression [770]
PEA15 OTKCKTSX Strong Biomarker [546]
PELI1 OTMLBCLC Strong Biomarker [771]
PER2 OTU2B1DJ Strong Genetic Variation [772]
PER3 OTVKYVJA Strong Altered Expression [273]
PGLYRP2 OTF8319A Strong Biomarker [773]
PIAS2 OTJLSC3V Strong Altered Expression [774]
PIAS3 OT3TWH9R Strong Altered Expression [775]
PIK3C2B OTY2PROB Strong Biomarker [776]
PIK3C3 OTLUM9L7 Strong Biomarker [777]
PINK1 OT50NR57 Strong Biomarker [778]
PITPNM1 OTIUYAG5 Strong Biomarker [779]
PITX1 OTA0UN4C Strong Altered Expression [780]
PKIB OT7C8GFN Strong Genetic Variation [190]
PLA1A OT2IXYNX Strong Biomarker [781]
PLAAT4 OTI66SAJ Strong Altered Expression [208]
PLIN2 OTRXJ9UN Strong Altered Expression [782]
PLIN3 OT9ZA7MR Strong Altered Expression [783]
PLIN5 OTV8G50L Strong Altered Expression [784]
PLXNB1 OTCA7JIT Strong Biomarker [785]
POLDIP3 OTTB5SV7 Strong Biomarker [405]
POLE3 OTOELRF6 Strong Biomarker [653]
POLRMT OT5Q8ZUJ Strong Biomarker [786]
POTEF OTV3WXYE Strong Genetic Variation [787]
POU2F1 OTK7ELJ0 Strong Biomarker [430]
PPIG OTZ8BTTM Strong Biomarker [788]
PPIL1 OTS5S837 Strong Biomarker [789]
PPP1R15A OTYG179K Strong Altered Expression [790]
PRB2 OTAD4JZ0 Strong Altered Expression [791]
PRDM6 OTKY12D9 Strong Biomarker [771]
PRF1 OTFVXD7H Strong Altered Expression [792]
PRH1 OTQZ6HX0 Strong Biomarker [793]
PRIM2 OTGT0KTF Strong Biomarker [261]
PRSS3 OTN3S5YB Strong Biomarker [794]
PSMD3 OT585WY8 Strong Biomarker [261]
PSMD7 OT7PZZ4K Strong Biomarker [366]
PSME3 OTSTC4YY Strong Altered Expression [795]
PTBP2 OTF4S7NE Strong Biomarker [413]
PTF1A OT7SWA57 Strong Biomarker [537]
PTGES3 OTPPQWI0 Strong Biomarker [161]
PXN OTVMMUOF Strong Biomarker [796]
QPRT OT6SKKLL Strong Biomarker [797]
RAB18 OTNMAQLS Strong Biomarker [798]
RAB1A OTKPHRD0 Strong Biomarker [799]
RAB1B OTAFCUAS Strong Biomarker [800]
RAB29 OTDZT6LP Strong Biomarker [801]
RAB32 OTTR4H7S Strong Altered Expression [802]
RAB40B OTCA9ZF5 Strong Posttranslational Modification [803]
RAB5A OTFR2KM4 Strong Biomarker [804]
RAB6A OTLS86J5 Strong Biomarker [804]
RAB7B OT60A0E9 Strong Biomarker [416]
RABEPK OTCZSREH Strong Biomarker [366]
RAD21 OTQS84ZF Strong Biomarker [642]
RAD23B OT0PGOG3 Strong Biomarker [261]
RAD51AP1 OTXM7UTD Strong Biomarker [805]
RAPGEF5 OT53VS75 Strong Biomarker [806]
RASGRF2 OT67DAGF Strong Biomarker [807]
RBL1 OTDEBFYC Strong Altered Expression [791]
RBM24 OTQI1AR1 Strong Biomarker [808]
RBM39 OTCMPTF9 Strong Genetic Variation [809]
RERE OT3G4GBZ Strong Genetic Variation [810]
RETN OTW5Z1NH Strong Biomarker [210]
RHEB OTFLTSEC Strong Altered Expression [811]
RILP OTT6K1GE Strong Altered Expression [416]
RIOK3 OTZYZVIX Strong Biomarker [618]
RNASE1 OTKZ7CO9 Strong Biomarker [812]
RNASE4 OTA5SZLC Strong Biomarker [799]
RNF139 OT0PR1X5 Strong Altered Expression [813]
ROBO3 OTPVG40S Strong Altered Expression [208]
RPL17 OTTYMPS6 Strong Biomarker [814]
RPP14 OT4OYFSK Strong Altered Expression [423]
RPS27A OTIIGGZ2 Strong Altered Expression [464]
RPS4X OTIH80EK Strong Altered Expression [815]
RPS6 OTT4D1LN Strong Biomarker [816]
RPTOR OT4TQZ9F Strong Biomarker [377]
RRAS OTBBF28C Strong Biomarker [161]
RSAD2 OTCA9WCM Strong Biomarker [817]
RTEL1 OTI3PJCT Strong Genetic Variation [818]
RTN3 OTGZ51QF Strong Biomarker [819]
SAG OTDNS3ZQ Strong Biomarker [820]
SART3 OTC1AM7S Strong Altered Expression [405]
SCAF1 OT16TM3N Strong Genetic Variation [600]
SDC3 OT1P0LJM Strong Biomarker [425]
SDC4 OTKUVUGZ Strong Biomarker [425]
SDHC OTC8G2MX Strong Biomarker [821]
SDK2 OTTBK3MH Strong Genetic Variation [157]
SEC14L2 OTJST64D Strong Biomarker [822]
SEC24C OTMTJBQ1 Strong Biomarker [823]
SEL1L OTC0FB7T Strong Biomarker [643]
SEMA6A OTDQ7QAW Strong Biomarker [824]
SERPINB4 OT88LHZ8 Strong Genetic Variation [825]
SF3B6 OTPRKS6S Strong Altered Expression [423]
SFRP2 OT8GZ0CA Strong Genetic Variation [826]
SH2D1A OTLU49I5 Strong Biomarker [153]
SHC2 OTTWMRNQ Strong Biomarker [827]
SIDT1 OTJM5S74 Strong Genetic Variation [828]
SIGLEC1 OTNWSQA9 Strong Altered Expression [829]
SIX6 OTD1RD9D Strong Biomarker [830]
SLC12A9 OTR7VRAK Strong Biomarker [262]
SMARCA2 OTSGJ8SV Strong Altered Expression [207]
SMIM1 OTWSFC2F Strong Biomarker [831]
SMIM10L2B OT04IG2N Strong Genetic Variation [832]
SMOC1 OTJG2JQY Strong Biomarker [833]
SMOC2 OTK1EQ49 Strong Biomarker [773]
SND1 OTT734JN Strong Altered Expression [405]
SNF8 OTRQA2AI Strong Biomarker [834]
SNRPD1 OTWKZV4E Strong Biomarker [835]
SOAT1 OTB4Y5RJ Strong Biomarker [697]
SOS1 OTTCWXC3 Strong Biomarker [836]
SPATA16 OT9GJBI3 Strong Genetic Variation [190]
SPATA2 OTOA45GL Strong Biomarker [814]
SPECC1 OTPEML48 Strong Biomarker [562]
SPINT2 OTQV7BKQ Strong Biomarker [837]
SPRR2A OT62ZU6B Strong Biomarker [838]
SPSB2 OT7ZVT8R Strong Biomarker [839]
SRSF4 OTLI7CU1 Strong Genetic Variation [321]
SRSF5 OTC5WP98 Strong Biomarker [677]
SSB OTCCTPBR Strong Biomarker [840]
ST13 OTNML6UP Strong Biomarker [537]
STAT2 OTO9G2RZ Strong Biomarker [443]
STAT5A OTBSJGN3 Strong Altered Expression [841]
STAT5B OTZVPEBT Strong Altered Expression [841]
STAU1 OTTR5311 Strong Biomarker [842]
STING1 OTDAP4G0 Strong Biomarker [843]
STON1 OT2HPUAI Strong Biomarker [580]
STX2 OTO2IDDR Strong Altered Expression [660]
STX4 OTQ7YUX1 Strong Biomarker [844]
STX7 OTHW3GEI Strong Biomarker [845]
SUB1 OTK71JYU Strong Altered Expression [423]
SURF4 OTCSXJ9C Strong Biomarker [846]
SUV39H2 OTU0F4LL Strong Biomarker [847]
SYCE1L OTXU44F3 Strong Altered Expression [724]
TAF8 OTWWGCHV Strong Genetic Variation [848]
TAP2 OTWSYFI7 Strong Genetic Variation [531]
TAPBP OTL81AVZ Strong Genetic Variation [531]
TAT OT2CJ91O Strong Biomarker [849]
TBC1D20 OTDL1T6E Strong Biomarker [799]
TBP OT6C0S52 Strong Biomarker [850]
TBPL2 OTDEC1KO Strong Altered Expression [851]
TIMELESS OTD8DCBJ Strong Biomarker [593]
TIMP4 OT8A68SW Strong Altered Expression [852]
TMED10 OTUXSHH7 Strong Biomarker [161]
TMED5 OT70W1J8 Strong Genetic Variation [319]
TMEM132A OTNUI7O1 Strong Biomarker [558]
TNFAIP6 OT1SLUZH Strong Biomarker [491]
TNFAIP8L2 OTII0RM0 Strong Biomarker [853]
TNPO1 OT7W2CM8 Strong Biomarker [377]
TNRC6A OT493IOM Strong Biomarker [854]
TNRC6C OTBR07PM Strong Biomarker [854]
TOMM34 OTH6MITE Strong Biomarker [855]
TOMM40 OTZDQ29F Strong Genetic Variation [856]
TOP3A OT3CKUI9 Strong Biomarker [460]
TOX OTE8BL5Z Strong Biomarker [857]
TPR OTUBBA4W Strong Biomarker [858]
TRAF2 OT1MEZZN Strong Biomarker [859]
TRAT1 OTMPUNPD Strong Altered Expression [860]
TRIB3 OTG5OS7X Strong Altered Expression [861]
TRIM14 OTLQKUG0 Strong Biomarker [862]
TRIM56 OTFGU8E3 Strong Altered Expression [863]
TRIM69 OTTEGTRD Strong Biomarker [449]
TRIO OT71X1AK Strong Biomarker [864]
ASPM OTKXQMNA Definitive Biomarker [865]
DCX OTISR7K3 Definitive Biomarker [207]
NCAN OT8OO6ZE Definitive Genetic Variation [866]
SARNP OTE0OVK5 Definitive Biomarker [867]
------------------------------------------------------------------------------------
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References

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6 2011 Pipeline of Pharmasset.
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12 2011 Pipeline of Boehringer Ingelheim Pharma.
13 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
14 Clinical pipeline report, company report or official report of Biotest Pharmaceuticals.
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19 ClinicalTrials.gov (NCT02384460) Study of Efficacy and Safety of SD-101 Cream in Patients With Epidermolysis Bullosa. U.S. National Institutes of Health.
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30 2011 Pipeline of Bristol-Myers Squibb.
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33 2011 Pipeline of Can-Fite BioPharm.
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35 ClinicalTrials.gov (NCT00277238) CPG10101 Combination Therapy For The Treatment Of Hepatitis C In Non-Responder (Null And Partial Responder) Hepatitis C Virus (HCV) Genotype 1 Infected Subjects. U.S.National Institutes of Health.
36 2011 Pipeline of InterMune.
37 Clinical pipeline report, company report or official report of Pfizer (2011).
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42 ClinicalTrials.gov (NCT02202980) Efficacy and Safety of Oral Regimens for the Treatment of Chronic HCV Infection. U.S. National Institutes of Health.
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45 Clinical pipeline report, company report or official report of Amarillo Biosciences.
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47 Clinical pipeline report, company report or official report of Amarillo biosciences.
48 Clinical pipeline report, company report or official report of Hanall biopharma.
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51 Interferons and viral infections. Biofactors. 2009 Jan-Feb;35(1):14-20.
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53 Human monoclonal antibody MBL-HCV1 delays HCV viral rebound following liver transplantation: a randomized controlled study. Am J Transplant. 2013 Apr;13(4):1047-54.
54 2011 Pipeline of Santaris Pharma.
55 ClinicalTrials.gov (NCT00433108) Trial of MitoQ for Raised Liver Enzymes Due to Hepatitis C. U.S. National Institutes of Health.
56 Clinical pipeline report, company report or official report of Merck (2011).
57 ClinicalTrials.gov (NCT01226797) Safety And Efficacy Of Oral PF-4136309 In Patients With Chronic Hepatitis C Infection And Abnormal Liver Enzymes. U.S. National Institutes of Health.
58 ClinicalTrials.gov (NCT00810758) Multiple Oral Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PF-04878691. U.S. National Institutes of Health.
59 ClinicalTrials.gov (NCT01859962) Study of PPI-668, BI 207127 and Faldaprevir, With and Without Ribavirin, in the Treatment of Chronic Hepatitis C. U.S. National Institutes of Health.
60 ClinicalTrials.gov (NCT02426359) Safety and Efficacy Study of Q301 in Moderate to Severe Atopic Dermatitis Patients. U.S. National Institutes of Health.
61 A phase II study of recombinant interferon-beta (r-hIFN-beta 1a) in combination with 5-fluorouracil (5-FU) in the treatment of patients with advanced colorectal carcinoma. Br J Cancer. 1997;75(3):423-6.
62 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800040120)
63 SCY-635, a novel nonimmunosuppressive analog of cyclosporine that exhibits potent inhibition of hepatitis C virus RNA replication in vitro. Antimicrob Agents Chemother. 2010 Feb;54(2):660-72.
64 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034971)
65 ClinicalTrials.gov (NCT01726946) A Phase 2 Study to Evaluate the Safety and Efficacy of VX-135 With Ribavirin in Treatment-Naive Subjects With Chronic Hepatitis C. U.S. National Institutes of Health.
66 2011 Pipeline of Vertex.
67 ClinicalTrials.gov (NCT00800007) Study of Safety and Tolerability of Multiple Intravenous Doses of ANZ-521 in Adults With Chronic Hepatitis C Virus. U.S. National Institutes of Health.
68 ClinicalTrials.gov (NCT00522808) A Study of the PK, Safety and Antiviral Activity of A-831 in HCV Carriers. U.S. National Institutes of Health.
69 ClinicalTrials.gov (NCT01825980) Proof of Concept Study to Determine the Safety and Antiviral Effect of BZF961 With or Without Ritonavir Boosting in Hepatitis C Virus Infected Patients. U.S. NationalInstitutes of Health.
70 ClinicalTrials.gov (NCT00563173) Phase I/IIa Dose Ranging CHRONVAC-C Study in Chronic HCV Patients. U.S. National Institutes of Health.
71 ClinicalTrials.gov (NCT00807001) Double-Blind, Dose-Escalation Study of IDX184 in Chronic Hepatitis C Treatment-Naive Subjects. U.S. National Institutes of Health.
72 ClinicalTrials.gov (NCT01508156) Study of Hepatitis C Virus (HCV) Nonstructural Protein 5a (NS5A) Inhibitor IDX719 in Healthy and HCV-Infected Participants (MK-1894-001). U.S. National Institutes of Health.
73 ClinicalTrials.gov (NCT01433133) Safety and Biological Activity of InfraDure Biopump Secreting Sustained Interferon in HCV Patients. U.S. National Institutes of Health.
74 Clinical pipeline report, company report or official report of Okairos.
75 ClinicalTrials.gov (NCT01899092) Safety and Efficacy Study of Single Doses of TT-034 in Patients With Chronic Hepatitis C. U.S. National Institutes of Health.
76 Emerging drugs for hepatitis C. Expert Opin Emerg Drugs. 2008 Mar;13(1):1-19.
77 Clinical pipeline report, company report or official report of Abbott Laboratories (2011)
78 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034265)
79 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800039148)
80 ClinicalTrials.gov (NCT00906256) Clinical Pharmacology Study of AZD7295 in Healthy Subjects. U.S. National Institutes of Health.
81 ClinicalTrials.gov (NCT01096576) A Study of Balapiravir in Patients With Dengue Virus Infection. U.S. National Institutes of Health.
82 Nautilus Biotech Receives FDA Approval for Phase 1 Clinical Trial in the USA for Oral Belerofon(R), its Long-Lasting, Interferon-Alpha Drug. Nautilus Biotech. MAY 14, 2007.
83 2011 Pipeline of Biotron.
84 ClinicalTrials.gov (NCT02760758) A Study of CDI-31244: A Novel NNI in HV and HCV Infected Subjects. U.S. National Institutes of Health.
85 The hepatitis C virus (HCV) NS4B RNA binding inhibitor clemizole is highly synergistic with HCV protease inhibitors. J Infect Dis. 2010 Jul 1;202(1):65-74.
86 ClinicalTrials.gov (NCT01856426) Proof of Concept Study for Safety and Efficacy of EDP239 in Hepatitis C Subjects. U.S. National Institutes of Health.
87 ClinicalTrials.gov (NCT01316237) A Study Evaluating the Safety, Tolerability, Pharmacokinetics and Antiviral Activity of GS-6620 in Treatment Naive Subjects With Chronic Hepatitis C Virus Infection. U.S. National Institutes of Health.
88 ClinicalTrials.gov (NCT00439959) Monotherapy Versus Placebo Over 14 or 17 Days in Healthy and Hepatitis C Infected Adults. U.S. National Institutes of Health.
89 ClinicalTrials.gov (NCT00500747) Chiron Corp HCV E1/E2 Vaccine. U.S. National Institutes of Health.
90 ClinicalTrials.gov (NCT04318379) Therapeutic Hepatitis C Virus Vaccine. U.S. National Institutes of Health.
91 Clinical pipeline report, company report or official report of Idenix (2011).
92 Clinical pipeline report, company report or official report of Inovio Pharmaceuticals.
93 ClinicalTrials.gov (NCT01482611) A Study in Healthy Participants Investigating the Safety, Tolerability and Plasma Pharmacokinetics (PK) of Single Oral Doses of JNJ-47910382. U.S. National Institutesof Health.
94 ClinicalTrials.gov (NCT02617615) A Trial to Evaluate Safety, Tolerability, PK and Antiviral Activity of MB-110 in Hepatitis C Virus Infected Patients. U.S. National Institutes of Health.
95 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800037271)
96 ClinicalTrials.gov (NCT01329913) Safety, Pharmacokinetics, and Pharmacodynamics of MK-6325 in Hepatitis C Virus (HCV) Infections (MK-6325-003). U.S. National Institutes of Health.
97 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800029167)
98 ClinicalTrials.gov (NCT01928147) A Phase 1a/1b Study of PPI-383 in Healthy Adults and Hepatitis C Patients. U.S. National Institutes of Health.
99 2011 Pipeline of Presidio.
100 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800031996)
101 ClinicalTrials.gov (NCT01181024) A Study on Safety, Tolerability and Pharmacokinetics of RO5303253 in Healthy Volunteers and Patients With Chronic Hepatitis C Genotype 1. U.S. National Institutes of Health.
102 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034330)
103 ClinicalTrials.gov (NCT01813552) To Evaluate the Effect of Ritonavir or Omeprazole on the Pharmacokinetics of Samatasvir (IDX719) in Healthy Participants (MK-1894-006). U.S. National Institutes of Health.
104 ClinicalTrials.gov (NCT01202825) TMC647055HPC1001 - First-in-human Trial to Examine Safety, Tolerability and Pharmacokinetics (How the Drug is Absorbed Into the Bloodstream) of Increasing Single OralDoses and of Increasing Repeated Oral Doses of TMC647055 in Healthy Volunteers and in Hepatitis C Virus Infected Patients. U.S. National Institutes of Health.
105 Clinical pipeline report, company report or official report of Medivir (2011).
106 ClinicalTrials.gov (NCT00557583) Evaluation of Safety and Pharmacokinetics of Single Doses of VBY-376 in Healthy Adults. U.S. National Institutes of Health.
107 ClinicalTrials.gov (NCT00300807) Study of XTL6865 in Patients With Chronic Hepatitis C Virus Infection. U.S. National Institutes of Health.
108 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011335)
109 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800031314)
110 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800012104)
111 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009426)
112 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017555)
113 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005492)
114 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026937)
115 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800025214)
116 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010620)
117 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011886)
118 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800016469)
119 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800022995)
120 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021992)
121 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800031987)
122 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011431)
123 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800032623)
124 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021901)
125 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018541)
126 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018157)
127 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027431)
128 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800032147)
129 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018944)
130 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018979)
131 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800033302)
132 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800042373)
133 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800023649)
134 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800029954)
135 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010742)
136 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800030836)
137 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015702)
138 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018937)
139 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027514)
140 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800024593)
141 Evaluation of hepatitis C virus glycoprotein E2 for vaccine design: an endoplasmic reticulum-retained recombinant protein is superior to secreted recombinant protein and DNA-based vaccine candidates.J Virol. 2000 Aug;74(15):6885-92.
142 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019390)
143 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800023059)
144 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800024904)
145 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027653)
146 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
147 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2625).
148 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800032074)
149 Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977.J Biol Chem.2010 Nov 5;285(45):34337-47.
150 FDA Approved Drug Products from FDA Official Website. 2015. Application Number: (ANDA) 207931.
151 Resistance to mericitabine, a nucleoside analogue inhibitor of HCV RNA-dependent RNA polymerase. Antivir Ther. 2012;17(3):411-23.
152 Active Hepatitis C Leading to Refractory Thrombotic Thrombocytopenic Purpura - A Dubious Association and The Challenges Faced in Management.Cureus. 2019 Jul 16;11(7):e5147. doi: 10.7759/cureus.5147.
153 Dual function of the NK cell receptor 2B4 (CD244) in the regulation of HCV-specific CD8+ T cells.PLoS Pathog. 2011 May;7(5):e1002045. doi: 10.1371/journal.ppat.1002045. Epub 2011 May 19.
154 APOBEC3G is a restriction factor of EV71 and mediator of IMB-Z antiviral activity.Antiviral Res. 2019 May;165:23-33. doi: 10.1016/j.antiviral.2019.03.005. Epub 2019 Mar 9.
155 Amphipathic -helices in apolipoproteins are crucial to the formation of infectious hepatitis C virus particles.PLoS Pathog. 2014 Dec 11;10(12):e1004534. doi: 10.1371/journal.ppat.1004534. eCollection 2014 Dec.
156 Plasma apolipoprotein H limits HCV replication and associates with response to NS3 protease inhibitors-based therapy.Liver Int. 2015 Jul;35(7):1833-44. doi: 10.1111/liv.12759. Epub 2015 Jan 23.
157 A new 3p25 locus is associated with liver fibrosis progression in human immunodeficiency virus/hepatitis C virus-coinfected patients.Hepatology. 2016 Nov;64(5):1462-1472. doi: 10.1002/hep.28695. Epub 2016 Jul 29.
158 The association of CCL3 and CCL4 polymorphisms with HCV clearance in Chinese Han population.Gene. 2018 Jul 30;665:35-40. doi: 10.1016/j.gene.2018.04.079. Epub 2018 Apr 27.
159 Genetic variants in the CCR gene cluster and spontaneous viral elimination in hepatitis C-infected patients.Clin Exp Immunol. 2004 May;136(2):328-33. doi: 10.1111/j.1365-2249.2004.02444.x.
160 Elevated liver stiffness is linked to increased biomarkers of inflammation and immune activation in HIV/hepatitis C virus-coinfected patients.AIDS. 2018 Jun 1;32(9):1095-1105. doi: 10.1097/QAD.0000000000001787.
161 Processing of hepatitis C virus core protein is regulated by its C-terminal sequence.J Med Virol. 2003 Mar;69(3):357-66. doi: 10.1002/jmv.10297.
162 Hepatitis C virus infection mediates cholesteryl ester synthesis to facilitate infectious particle production.J Gen Virol. 2014 Sep;95(Pt 9):1900-1910. doi: 10.1099/vir.0.065300-0. Epub 2014 May 24.
163 Host cell kinases and the hepatitis C virus life cycle.Biochim Biophys Acta. 2015 Oct;1854(10 Pt B):1657-62. doi: 10.1016/j.bbapap.2015.04.011. Epub 2015 Apr 18.
164 Binding of Free and Immune Complex-Associated Hepatitis C Virus to Erythrocytes Is Mediated by the Complement System.Hepatology. 2018 Dec;68(6):2118-2129. doi: 10.1002/hep.30087. Epub 2018 Nov 1.
165 CYP1A2 is a predictor of HCC recurrence in HCV-related chronic liver disease: A retrospective multicentric validation study.Dig Liver Dis. 2017 Apr;49(4):434-439. doi: 10.1016/j.dld.2016.12.002. Epub 2016 Dec 16.
166 Activation of PERK-Nrf2 oncogenic signaling promotes Mdm2-mediated Rb degradation in persistently infected HCV culture.Sci Rep. 2017 Aug 23;7(1):9223. doi: 10.1038/s41598-017-10087-6.
167 Hepatitis C virus core protein targets 4E-BP1 expression and phosphorylation and potentiates Myc-induced liver carcinogenesis in transgenic mice.Oncotarget. 2017 Apr 20;8(34):56228-56242. doi: 10.18632/oncotarget.17280. eCollection 2017 Aug 22.
168 Serum IP-10 levels and increased DPPIV activity are linked to circulating CXCR3+ T cells in cholestatic HCV patients.PLoS One. 2018 Dec 3;13(12):e0208225. doi: 10.1371/journal.pone.0208225. eCollection 2018.
169 Permissivity of primary human hepatocytes and different hepatoma cell lines to cell culture adapted hepatitis C virus.PLoS One. 2013 Aug 5;8(8):e70809. doi: 10.1371/journal.pone.0070809. Print 2013.
170 Multiplex diagnosis of viral infectious diseases (AIDS, hepatitis C, and hepatitis A) based on point of care lateral flow assay using engineered proteinticles.Biosens Bioelectron. 2015 Jul 15;69:213-25. doi: 10.1016/j.bios.2015.02.033. Epub 2015 Feb 25.
171 Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection.Gut. 2010 Aug;59(8):1120-6. doi: 10.1136/gut.2009.202267. Epub 2010 Jun 29.
172 The potential role of interleukin-37 in infectious diseases.Int Rev Immunol. 2020;39(1):3-10. doi: 10.1080/08830185.2019.1677644. Epub 2019 Oct 21.
173 Up-regulation of circulating miRNA146a correlates with viral load via IRAK1 and TRAF6 in hepatitis C virus-infected patients.Virus Res. 2017 Jun 15;238:24-28. doi: 10.1016/j.virusres.2017.05.026. Epub 2017 Jun 3.
174 Association of human platelet antigens polymorphisms with susceptibility to hepatitis C virus infection in Chinese population.Int J Immunogenet. 2017 Dec;44(6):337-342. doi: 10.1111/iji.12341. Epub 2017 Sep 20.
175 Human intrahepatic CD69?CD8+ T cells have a tissue resident memory T cell phenotype with reduced cytolytic capacity.Sci Rep. 2017 Jul 21;7(1):6172. doi: 10.1038/s41598-017-06352-3.
176 NKG2A is a NK cell exhaustion checkpoint for HCV persistence.Nat Commun. 2019 Apr 3;10(1):1507. doi: 10.1038/s41467-019-09212-y.
177 Immunohistochemical and electron microscopic morphometric image analysis of hepatocellular carcinoma in association of HCV infection.Ultrastruct Pathol. 2018 Mar-Apr;42(2):97-107. doi: 10.1080/01913123.2017.1422065. Epub 2018 Feb 9.
178 High Serum Lipopolysaccharide-Binding Protein Level in Chronic Hepatitis C Viral Infection Is Reduced by Anti-Viral Treatments.PLoS One. 2017 Jan 20;12(1):e0170028. doi: 10.1371/journal.pone.0170028. eCollection 2017.
179 Transforming Growth Factor Acts as a Regulatory Molecule for Lipogenic Pathways among Hepatitis C Virus Genotype-Specific Infections.J Virol. 2019 Aug 28;93(18):e00811-19. doi: 10.1128/JVI.00811-19. Print 2019 Sep 15.
180 Lipoprotein lipase liberates free fatty acids to inhibit HCV infection and prevent hepatic lipid accumulation.Cell Microbiol. 2017 Apr;19(4). doi: 10.1111/cmi.12673. Epub 2016 Nov 25.
181 Circulating tumor and cancer stem cells in hepatitis C virus-associated liver disease.World J Gastroenterol. 2014 Dec 28;20(48):18240-8. doi: 10.3748/wjg.v20.i48.18240.
182 SKI-1/S1P inhibitor PF-429242 impairs the onset of HCV infection.Antiviral Res. 2015 Mar;115:94-104. doi: 10.1016/j.antiviral.2014.12.017. Epub 2015 Jan 5.
183 Minichromosome maintenance protein-2-positive portal tract lymphocytes distinguish acute cellular rejection from hepatitis C virus recurrence after liver transplantation.Liver Transpl. 2009 Mar;15(3):306-12. doi: 10.1002/lt.21680.
184 Binding of cellular nucleolin with the viral core RNA G-quadruplex structure suppresses HCV replication.Nucleic Acids Res. 2019 Jan 10;47(1):56-68. doi: 10.1093/nar/gky1177.
185 Hepatitis C virus core protein interacts with cellular metastasis suppressor Nm23-H1 and promotes cell migration and invasion.Arch Virol. 2019 May;164(5):1271-1285. doi: 10.1007/s00705-019-04151-x. Epub 2019 Mar 11.
186 Liver X receptor -mediated regulation of lipogenesis by core and NS5A proteins contributes to HCV-induced liver steatosis and HCV replication.Lab Invest. 2012 Aug;92(8):1191-202. doi: 10.1038/labinvest.2012.88. Epub 2012 May 28.
187 HA1077 displays synergistic activity with daclatasvir against hepatitis C virus and suppresses the emergence of NS5A resistance-associated substitutions in mice.Sci Rep. 2018 Aug 20;8(1):12469. doi: 10.1038/s41598-018-30460-3.
188 Protein phosphatase 2A promotes hepatocellular carcinogenesis in the diethylnitrosamine mouse model through inhibition of p53.Carcinogenesis. 2014 Jan;35(1):114-22. doi: 10.1093/carcin/bgt258. Epub 2013 Jul 29.
189 Genetic variants in antigen presentation-related genes influence susceptibility to hepatitis C virus and viral clearance: a case control study.BMC Infect Dis. 2014 Dec 21;14:716. doi: 10.1186/s12879-014-0716-8.
190 Impact of IFNL4 Genetic Variants on Sustained Virologic Response and Viremia in Hepatitis C Virus Genotype 3 Patients.J Interferon Cytokine Res. 2019 Oct;39(10):642-649. doi: 10.1089/jir.2019.0013. Epub 2019 Jul 1.
191 lncRNA HULC facilitates efficient loading of HCV-core protein onto lipid droplets and subsequent virus-particle release.Cell Microbiol. 2019 Oct;21(10):e13086. doi: 10.1111/cmi.13086. Epub 2019 Jul 22.
192 Genomic variants link to hepatitis C racial disparities.Oncotarget. 2017 Aug 1;8(35):59455-59475. doi: 10.18632/oncotarget.19755. eCollection 2017 Aug 29.
193 Interferon--induced CD100 on nave CD8(+) T cells enhances antiviral responses to hepatitis C infection through CD72 signal transduction.J Int Med Res. 2017 Feb;45(1):89-100. doi: 10.1177/0300060516676136. Epub 2017 Jan 12.
194 SERPINB3 expression on B-cell surface in autoimmune diseases and hepatitis C virus-related chronic liver infection.Exp Biol Med (Maywood). 2012 Jul;237(7):793-802. doi: 10.1258/ebm.2012.012024. Epub 2012 Jul 24.
195 Ferroportin-1 in the recurrence of hepatic iron overload after liver transplantation.Dig Liver Dis. 2009 Jul;41(7):e17-20. doi: 10.1016/j.dld.2008.01.020. Epub 2008 Mar 11.
196 TM6SF2 Promotes Lipidation and Secretion of Hepatitis C Virus in Infected Hepatocytes.Gastroenterology. 2018 Dec;155(6):1923-1935.e8. doi: 10.1053/j.gastro.2018.08.027. Epub 2018 Aug 23.
197 Hyperhomocysteinemia and the MTHFR C677T polymorphism promote steatosis and fibrosis in chronic hepatitis C patients.Hepatology. 2005 May;41(5):995-1003. doi: 10.1002/hep.20664.
198 The role of tacstd-2 level in hepatitis C patients (controlled clinical research).Libyan J Med. 2019 Dec;14(1):1622363. doi: 10.1080/19932820.2019.1622363.
199 HCV-specific CD4+ T cells of patients with acute and chronic HCV infection display high expression of TIGIT and other co-inhibitory molecules.Sci Rep. 2019 Jul 23;9(1):10624. doi: 10.1038/s41598-019-47024-8.
200 Peripheral blood and hepatic Toll-like receptor 7 expression and interferon lambda 1 levels in chronic hepatitis C: Relation to virus replication and liver injury.Microb Pathog. 2019 Jun;131:65-74. doi: 10.1016/j.micpath.2019.03.032. Epub 2019 Mar 26.
201 Role of interferon gamma and tumor necrosis factor-related apoptosis-inducing ligand receptor 1 single nucleotide polymorphism in natural clearance and treatment response of HCV infection.Viral Immunol. 2015 May;28(4):222-8. doi: 10.1089/vim.2014.0111. Epub 2015 Mar 23.
202 Association of BAFF -871C/T Promoter Polymorphism with Hepatitis C-Related Mixed Cryoglobulinemia in a Cohort of Egyptian Patients.Mol Diagn Ther. 2015 Apr;19(2):99-106. doi: 10.1007/s40291-015-0134-7.
203 Hepatitis C virus-induced natural killer cell proliferation involves monocyte-derived cells and the OX40/OX40L axis.J Hepatol. 2018 Mar;68(3):421-430. doi: 10.1016/j.jhep.2017.10.021. Epub 2017 Nov 1.
204 Thymic stromal lymphopoietin in hepatitis C virus-related cryoglobulinemic vasculitis: gene expression level and protein distribution.Arthritis Res Ther. 2015 Mar 15;17(1):62. doi: 10.1186/s13075-015-0581-x.
205 mTORC1 restricts hepatitis C virus RNA replication through ULK1-mediated suppression of miR-122 and facilitates post-replication events.J Gen Virol. 2020 Jan;101(1):86-95. doi: 10.1099/jgv.0.001356.
206 Effect of IL15 rs10833 and SCARB1 rs10846744 on virologic responses in chronic hepatitis C patients treated with pegylated interferon- and ribavirin.Gene. 2017 Sep 30;630:28-34. doi: 10.1016/j.gene.2017.08.005. Epub 2017 Aug 4.
207 Inflammatory and oncogenic roles of a tumor stem cell marker doublecortin-like kinase (DCLK1) in virus-induced chronic liver diseases.Oncotarget. 2015 Aug 21;6(24):20327-44. doi: 10.18632/oncotarget.3972.
208 Induction of Selenoprotein P mRNA during Hepatitis C Virus Infection Inhibits RIG-I-Mediated Antiviral Immunity.Cell Host Microbe. 2019 Apr 10;25(4):588-601.e7. doi: 10.1016/j.chom.2019.02.015.
209 Impact of T cell activation, HIV replication and hepatitis C virus infection on neutrophil CD64 expression.Cytometry B Clin Cytom. 2017 Nov;92(6):492-497. doi: 10.1002/cyto.b.21385. Epub 2016 Jul 4.
210 Circulating Resistin Is Associated with Plasma Glucagon-Like Peptide-1 in Cirrhotic Patients with Hepatitis C Virus Genotype-4 Infection.Endocr Res. 2020 Feb;45(1):17-23. doi: 10.1080/07435800.2019.1627551. Epub 2019 Jun 10.
211 Genetic prevention of hepatitis C virus-induced liver fibrosis by allele-specific downregulation of MERTK.Hepatol Res. 2017 Jul;47(8):826-830. doi: 10.1111/hepr.12810. Epub 2016 Sep 29.
212 The Clinical Features of Patients with Chronic Hepatitis C Virus Infections Are Associated with Killer Cell Immunoglobulin-Like Receptor Genes and Their Expression on the Surface of Natural Killer Cells.Front Immunol. 2018 Jan 5;8:1912. doi: 10.3389/fimmu.2017.01912. eCollection 2017.
213 Magnetic Resonance Elastography Shear Wave Velocity Correlates with Liver Fibrosis and Hepatic Venous Pressure Gradient in Adults with Advanced Liver Disease.Biomed Res Int. 2017;2017:2067479. doi: 10.1155/2017/2067479. Epub 2017 Apr 5.
214 GRIM-19 Restricts HCV Replication by Attenuating Intracellular Lipid Accumulation.Front Microbiol. 2017 Apr 11;8:576. doi: 10.3389/fmicb.2017.00576. eCollection 2017.
215 Correlation of CD81 and SCARB1 polymorphisms on virological responses in Iranian patients with chronic hepatitis C virus genotype 1.Infect Genet Evol. 2018 Aug;62:296-303. doi: 10.1016/j.meegid.2018.04.038. Epub 2018 Apr 30.
216 Stearoyl-CoA desaturase-1 is required for flavivirus RNA replication.Antiviral Res. 2019 May;165:42-46. doi: 10.1016/j.antiviral.2019.03.002. Epub 2019 Mar 7.
217 Infection of Hepatocytes With HCV Increases Cell Surface Levels of Heparan Sulfate Proteoglycans, Uptake of Cholesterol and Lipoprotein, and Virus Entry by Up-regulating SMAD6 and SMAD7.Gastroenterology. 2017 Jan;152(1):257-270.e7. doi: 10.1053/j.gastro.2016.09.033. Epub 2016 Sep 30.
218 Genetic polymorphisms of steroid hormone metabolizing enzymes and risk of liver cancer in hepatitis C-infected patients.J Hepatol. 2003 Oct;39(4):564-70. doi: 10.1016/s0168-8278(03)00355-6.
219 Association of IL-28B, TBX21 gene polymorphisms and predictors of virological response for chronic hepatitis C.Arch Virol. 2018 May;163(5):1253-1262. doi: 10.1007/s00705-018-3750-9. Epub 2018 Feb 5.
220 FUSE Binding Protein 1 Facilitates Persistent Hepatitis C Virus Replication in Hepatoma Cells by Regulating Tumor Suppressor p53.J Virol. 2015 Aug;89(15):7905-21. doi: 10.1128/JVI.00729-15. Epub 2015 May 20.
221 Interactions between the Hepatitis C Virus Nonstructural 2 Protein and Host Adaptor Proteins 1 and 4 Orchestrate Virus Release.mBio. 2018 Mar 13;9(2):e02233-17. doi: 10.1128/mBio.02233-17.
222 Protein Abundance of Hepatic Drug Transporters in Patients With Different Forms of Liver Damage.Clin Pharmacol Ther. 2020 May;107(5):1138-1148. doi: 10.1002/cpt.1717. Epub 2019 Dec 17.
223 LPAC syndrome associated with deletion of the full exon 4 in a ABCB4 genetic mutation in a patient with hepatitis C.Rev Esp Enferm Dig. 2014 Dec;106(8):544-7.
224 Atypical Chemokine Receptor 1 Polymorphism can not Affect Susceptibility to Hepatitis C Virus.Balkan Med J. 2017 Aug 4;34(4):308-312. doi: 10.4274/balkanmedj.2016.0766. Epub 2017 Apr 6.
225 Pre-vaccine plasma levels of soluble inflammatory indices negatively predict responses to HAV, HBV, and tetanus vaccines in HCV and HIV infection.Vaccine. 2018 Jan 25;36(4):453-460. doi: 10.1016/j.vaccine.2017.12.018. Epub 2017 Dec 16.
226 Activity of alcohol dehydrogenase isoenzymes and aldehyde dehydrogenase in sera of patients with hepatitis C.Arch Med Sci. 2018 Mar;14(2):281-287. doi: 10.5114/aoms.2016.60406. Epub 2016 Jun 7.
227 Adiponectin levels and insulin resistance among patients with chronic hepatitis C.Acta Trop. 2018 Feb;178:258-263. doi: 10.1016/j.actatropica.2017.12.004. Epub 2017 Dec 5.
228 TNFalpha-dependent hepatic steatosis and liver degeneration caused by mutation of zebrafish S-adenosylhomocysteine hydrolase.Development. 2009 Mar;136(5):865-75. doi: 10.1242/dev.027565.
229 Lifetime methamphetamine dependence is associated with cerebral microgliosis in HIV-1-infected adults.J Neurovirol. 2016 Oct;22(5):650-660. doi: 10.1007/s13365-016-0441-8. Epub 2016 Apr 20.
230 Hepatitis C virus core protein triggers abnormal porphyrin metabolism in human hepatocellular carcinoma cells.PLoS One. 2018 Jun 1;13(6):e0198345. doi: 10.1371/journal.pone.0198345. eCollection 2018.
231 Increased Circulating VAP-1 Levels Are Associated with Liver Fibrosis in Chronic Hepatitis C Infection.J Clin Med. 2019 Jan 17;8(1):103. doi: 10.3390/jcm8010103.
232 Increased hepatic expression of miRNA-122 in patients infected with HCV genotype 3.Med Microbiol Immunol. 2016 Apr;205(2):111-7. doi: 10.1007/s00430-015-0431-0. Epub 2015 Aug 14.
233 Hepatitis C virus replication and Golgi function in brefeldin a-resistant hepatoma-derived cells.PLoS One. 2013 Sep 18;8(9):e74491. doi: 10.1371/journal.pone.0074491. eCollection 2013.
234 Regulation of Apolipoprotein E Trafficking by Hepatitis C Virus-Induced Autophagy.J Virol. 2018 Jun 29;92(14):e00211-18. doi: 10.1128/JVI.00211-18. Print 2018 Jul 15.
235 Safety and Efficacy of Ombitasvir/Paritaprevir/Ritonavir Plus Dasabuvir With or Without Ribavirin in HCV-Infected Patients Taking Concomitant Acid-Reducing Agents.Am J Gastroenterol. 2016 Jun;111(6):845-51. doi: 10.1038/ajg.2016.108. Epub 2016 Apr 5.
236 MicroRNA-let-7c suppresses hepatitis C virus replication by targeting Bach1 for induction of haem oxygenase-1 expression.J Viral Hepat. 2019 Jun;26(6):655-665. doi: 10.1111/jvh.13072. Epub 2019 Mar 13.
237 Circulating CXCR3(+) Tfh cells positively correlate with neutralizing antibody responses in HCV-infected patients.Sci Rep. 2019 Jul 12;9(1):10090. doi: 10.1038/s41598-019-46533-w.
238 Expression of Biliverdin Reductase A in peripheral blood leukocytes is associated with treatment response in HCV-infected patients.PLoS One. 2013;8(3):e57555. doi: 10.1371/journal.pone.0057555. Epub 2013 Mar 11.
239 Antiviral activity of bone morphogenetic proteins and activins.Nat Microbiol. 2019 Feb;4(2):339-351. doi: 10.1038/s41564-018-0301-9. Epub 2018 Dec 3.
240 Hepcidin/ferroportin expression levels involve efficacy of pegylated-interferon plus ribavirin in hepatitis C virus-infected liver.World J Gastroenterol. 2015 Mar 21;21(11):3291-9. doi: 10.3748/wjg.v21.i11.3291.
241 Bromodomain containing protein represses the Ras/Raf/MEK/ERK pathway to attenuate human hepatoma cell proliferation during HCV infection.Cancer Lett. 2016 Feb 1;371(1):107-16. doi: 10.1016/j.canlet.2015.11.027. Epub 2015 Nov 24.
242 CD8+ T cells of chronic HCV-infected patients express multiple negative immune checkpoints following stimulation with HCV peptides.Cell Immunol. 2017 Mar;313:1-9. doi: 10.1016/j.cellimm.2016.12.002. Epub 2016 Dec 16.
243 Impact of novel NS5A resistance-associated substitutions of hepatitis C virus detected in treatment-experienced patients.Sci Rep. 2019 Apr 5;9(1):5722. doi: 10.1038/s41598-019-42114-z.
244 The Hepatitis C Virus-induced NLRP3 Inflammasome Activates the Sterol Regulatory Element-binding Protein (SREBP) and Regulates Lipid Metabolism.J Biol Chem. 2016 Feb 12;291(7):3254-67. doi: 10.1074/jbc.M115.694059. Epub 2015 Dec 23.
245 HCV Induces Telomerase Reverse Transcriptase, Increases Its Catalytic Activity, and Promotes Caspase Degradation in Infected Human Hepatocytes.PLoS One. 2017 Jan 5;12(1):e0166853. doi: 10.1371/journal.pone.0166853. eCollection 2017.
246 Hepatitis C virus enters liver cells using the CD81 receptor complex proteins calpain-5 and CBLB.PLoS Pathog. 2018 Jul 19;14(7):e1007111. doi: 10.1371/journal.ppat.1007111. eCollection 2018 Jul.
247 Hepatitis C virus induces the expression of CCL17 and CCL22 chemokines that attract regulatory T cells to the site of infection.J Hepatol. 2011 Mar;54(3):422-31. doi: 10.1016/j.jhep.2010.07.014. Epub 2010 Sep 26.
248 Identification and functional analysis of a core gene module associated with hepatitis C virus-induced human hepatocellular carcinoma progression.Oncol Lett. 2018 May;15(5):6815-6824. doi: 10.3892/ol.2018.8221. Epub 2018 Mar 9.
249 Genetic variants in chemokine CC subfamily genes influence hepatitis C virus viral clearance.J Hum Genet. 2018 Jul;63(7):831-839. doi: 10.1038/s10038-018-0452-9. Epub 2018 Apr 27.
250 CCL20, a direct-acting pro-angiogenic chemokine induced by hepatitis C virus (HCV): Potential role in HCV-related liver cancer.Exp Cell Res. 2018 Nov 15;372(2):168-177. doi: 10.1016/j.yexcr.2018.09.023. Epub 2018 Oct 2.
251 Significance of Markers of Monocyte Activation (CD163 and sCD14) and Inflammation (IL-6) in Patients Admitted for Alcohol Use Disorder Treatment.Alcohol Clin Exp Res. 2020 Jan;44(1):152-158. doi: 10.1111/acer.14228. Epub 2019 Dec 3.
252 Enhanced RIG-I expression is mediated by interferon regulatory factor-2 in peripheral blood B cells from hepatitis C virus-infected patients.Biochem Biophys Res Commun. 2010 Jan 22;391(4):1623-8. doi: 10.1016/j.bbrc.2009.12.092. Epub 2009 Dec 23.
253 DC-SIGN Polymorphisms Associate with Risk of Hepatitis C Virus Infection Among Men who Have Sex with Men but not Among Injecting Drug Users.J Infect Dis. 2018 Jan 17;217(3):353-357. doi: 10.1093/infdis/jix587.
254 Programmed death-ligand 1 expression is an unfavorable prognostic factor of hepatocellular carcinoma after archiving sustained virologic response for hepatitis C virus infection.Oncol Lett. 2019 Aug;18(2):1458-1466. doi: 10.3892/ol.2019.10448. Epub 2019 Jun 7.
255 Identification of IL-10-secreting CD8(+)CD28(-)PD-1(+) regulatory T cells associated with chronic hepatitis C virus infection.Immunol Lett. 2018 Oct;202:16-22. doi: 10.1016/j.imlet.2018.07.008. Epub 2018 Jul 25.
256 Interaction of NK inhibitory receptor genes with HLA-C and MHC class II alleles in Hepatitis C virus infection outcome.Mol Immunol. 2008 May;45(9):2429-36. doi: 10.1016/j.molimm.2008.01.002. Epub 2008 Mar 4.
257 Hepatitis C Virus-Induced Myeloid-Derived Suppressor Cells Suppress NK Cell IFN- Production by Altering Cellular Metabolism via Arginase-1.J Immunol. 2016 Mar 1;196(5):2283-92. doi: 10.4049/jimmunol.1501881. Epub 2016 Jan 29.
258 Differential expression of candidate virus receptors in human T lymphocytes prone or resistant to infection with patient-derived hepatitis C virus.PLoS One. 2013 Apr 23;8(4):e62159. doi: 10.1371/journal.pone.0062159. Print 2013.
259 Hepatitis C virus infection upregulates CD55 expression on the hepatocyte surface and promotes association with virus particles.J Virol. 2013 Jul;87(14):7902-10. doi: 10.1128/JVI.00917-13. Epub 2013 May 8.
260 Distinct expression patterns in hepatitis B virus- and hepatitis C virus-infected hepatocellular carcinoma.World J Gastroenterol. 2008 Oct 21;14(39):6072-7. doi: 10.3748/wjg.14.6072.
261 Characterization of a Threonine-Rich Cluster in Hepatitis C Virus Nonstructural Protein 5A and Its Contribution to Hyperphosphorylation.J Virol. 2018 Nov 27;92(24):e00737-18. doi: 10.1128/JVI.00737-18. Print 2018 Dec 15.
262 Correction: Hepatitis C Virus Core Protein Down-Regulates p21Waf1/Cip1 and Inhibits Curcumin-Induced Apoptosis through MicroRNA-345 Targeting in Human Hepatoma Cells.PLoS One. 2017 Jul 7;12(7):e0181299. doi: 10.1371/journal.pone.0181299. eCollection 2017.
263 Physical and functional interaction between HCV core protein and the different p73 isoforms.Oncogene. 2003 May 1;22(17):2573-80. doi: 10.1038/sj.onc.1206333.
264 Direct, interferon-independent activation of the CXCL10 promoter by NF-B and interferon regulatory factor 3 during hepatitis C virus infection.J Virol. 2014 Feb;88(3):1582-90. doi: 10.1128/JVI.02007-13. Epub 2013 Nov 20.
265 Moving Towards Hepatitis C Microelimination Among People Living With Human Immunodeficiency Virus in Australia: The CEASE Study.Clin Infect Dis. 2020 Sep 12;71(6):1502-1510. doi: 10.1093/cid/ciz985.
266 Senescence mirrors the extent of liver fibrosis in chronic hepatitis C virus infection.Aliment Pharmacol Ther. 2018 Aug;48(3):270-280. doi: 10.1111/apt.14802. Epub 2018 Jun 4.
267 Claudin-targeted drug development using anti-claudin monoclonal antibodies to treat hepatitis and cancer.Ann N Y Acad Sci. 2017 Jun;1397(1):5-16. doi: 10.1111/nyas.13337. Epub 2017 Apr 17.
268 HCV glycoprotein E2 is a novel BDCA-2 ligand and acts as an inhibitor of IFN production by plasmacytoid dendritic cells.Blood. 2012 Nov 29;120(23):4544-51. doi: 10.1182/blood-2012-02-413286. Epub 2012 Oct 10.
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270 Carbamoyl phosphate synthetase 1 (CPS1) as a prognostic marker in chronic hepatitis C infection.APMIS. 2019 Feb;127(2):93-105. doi: 10.1111/apm.12917.
271 An intronic polymorphism in the corticotropin-releasing hormone receptor 2 gene increases susceptibility to HBV-related hepatocellular carcinoma in Chinese population.Hum Genet. 2010 Jan;127(1):75-81. doi: 10.1007/s00439-009-0750-6. Epub 2009 Oct 8.
272 Liraglutide Inhibits Hepatitis C Virus Replication Through an AMP Activated Protein Kinase Dependent Mechanism.Int J Mol Sci. 2019 Sep 14;20(18):4569. doi: 10.3390/ijms20184569.
273 Mutual antagonism between circadian protein period 2 and hepatitis C virus replication in hepatocytes.PLoS One. 2013 Apr 8;8(4):e60527. doi: 10.1371/journal.pone.0060527. Print 2013.
274 NFE2L2 is associated with NQO1 expression and low stage of hepatic fibrosis in patients with chronic hepatitis C.Adv Clin Exp Med. 2019 Sep;28(9):1237-1241. doi: 10.17219/acem/105852.
275 Identification of human kinases involved in hepatitis C virus replication by small interference RNA library screening.J Biol Chem. 2008 Jan 4;283(1):29-36. doi: 10.1074/jbc.M703988200. Epub 2007 Oct 19.
276 The alpha isoform of protein kinase CKI is responsible for hepatitis C virus NS5A hyperphosphorylation.J Virol. 2006 Nov;80(22):11305-12. doi: 10.1128/JVI.01465-06. Epub 2006 Aug 30.
277 Involvement of hepatitis C virus NS5A hyperphosphorylation mediated by casein kinase I- in infectious virus production.J Virol. 2014 Jul;88(13):7541-55. doi: 10.1128/JVI.03170-13. Epub 2014 Apr 23.
278 Hepatitis C virus-mediated inhibition of cathepsin S increases invariant-chain expression on hepatocyte surface.J Virol. 2012 Sep;86(18):9919-28. doi: 10.1128/JVI.00388-12. Epub 2012 Jul 3.
279 Single nucleotide polymorphisms of CXCL9-11 chemokines are associated with liver fibrosis in HIV/HCV-coinfected patients.J Acquir Immune Defic Syndr. 2015 Apr 1;68(4):386-95. doi: 10.1097/QAI.0000000000000491.
280 High MIG (CXCL9) plasma levels favours response to peginterferon and ribavirin in HCV-infected patients regardless of DPP4 activity.Liver Int. 2016 Mar;36(3):344-52. doi: 10.1111/liv.12932. Epub 2015 Sep 6.
281 Chemokine-Regulated Recruitment of Antigen-Specific T-Cell Subpopulations to the Liver in Acute and Chronic Hepatitis C Infection.J Infect Dis. 2019 Apr 16;219(9):1430-1438. doi: 10.1093/infdis/jiy679.
282 CYP24A1 genetic variants in the vitamin D metabolic pathway are involved in the outcomes of hepatitis C virus infection among high-risk Chinese population.Int J Infect Dis. 2019 Jul;84:80-88. doi: 10.1016/j.ijid.2019.04.032. Epub 2019 May 7.
283 Genetic polymorphisms of enzymes related to oral tegafur/uracil therapeutic efficacy in patients with hepatocellular carcinoma.Anticancer Drugs. 2013 Jul;24(6):617-22. doi: 10.1097/CAD.0b013e3283614fef.
284 Association of CYP2B6 Single-Nucleotide Polymorphisms Altering Efavirenz Metabolism With Hepatitis C Virus (HCV) Treatment Relapse Among Human Immunodeficiency Virus/HCV-Coinfected African Americans Receiving Ledipasvir/Sofosbuvir in the ION-4 Trial.Clin Infect Dis. 2018 Jun 1;66(12):1953-1956. doi: 10.1093/cid/cix1051.
285 Patterns of expression of cytochrome P450 genes in progression of hepatitis C virus-associated hepatocellular carcinoma.Int J Oncol. 2005 Sep;27(3):661-7.
286 Interferon-inducible cholesterol-25-hydroxylase restricts hepatitis C virus replication through blockage of membranous web formation.Hepatology. 2015 Sep;62(3):702-14. doi: 10.1002/hep.27913. Epub 2015 Jul 28.
287 Comparison of circulating, hepatocyte specific messenger RNA and microRNA as biomarkers for chronic hepatitis B and C.PLoS One. 2014 Mar 18;9(3):e92112. doi: 10.1371/journal.pone.0092112. eCollection 2014.
288 Ombitasvir/paritaprevir/ritonavir + dasabuvir +/- ribavirin in real world hepatitis C patients.World J Gastroenterol. 2019 May 14;25(18):2229-2239. doi: 10.3748/wjg.v25.i18.2229.
289 Minor contribution of CYP3A5 to the metabolism of hepatitis C protease inhibitor paritaprevir in vitro.Xenobiotica. 2019 Aug;49(8):935-944. doi: 10.1080/00498254.2018.1524947. Epub 2018 Nov 8.
290 Potential geographic "hotspots" for drug-injection related transmission of HIV and HCV and for initiation into injecting drug use in New York City, 2011-2015, with implications for the current opioid epidemic in the US.PLoS One. 2018 Mar 29;13(3):e0194799. doi: 10.1371/journal.pone.0194799. eCollection 2018.
291 Antiapoptotic regulation by hepatitis C virus core protein through up-regulation of inhibitor of caspase-activated DNase.Virology. 2003 Dec 5;317(1):24-35. doi: 10.1016/j.virol.2003.08.028.
292 Suppression of Hepatitis C Virus Genome Replication and Particle Production by a Novel Diacylglycerol Acyltransferases Inhibitor.Molecules. 2018 Aug 20;23(8):2083. doi: 10.3390/molecules23082083.
293 Hepatitis C virus infection alters lipid metabolism depending on IL28B polymorphism and viral genotype and modulates gene expression in vivo and in vitro.J Viral Hepat. 2014 Jan;21(1):19-24. doi: 10.1111/jvh.12209. Epub 2013 Nov 4.
294 Oxidative Stress and Immune Responses During Hepatitis C Virus Infection in Tupaia belangeri.Sci Rep. 2017 Aug 29;7(1):9848. doi: 10.1038/s41598-017-10329-7.
295 Hepatitis C epitopes from phage-displayed cDNA libraries and improved diagnosis with a chimeric antigen.J Med Virol. 2000 Feb;60(2):144-51.
296 Interaction of miR-125b-5p with Human antigen R mRNA: Mechanism of controlling HCV replication.Virus Res. 2018 Oct 15;258:1-8. doi: 10.1016/j.virusres.2018.09.006. Epub 2018 Sep 22.
297 Autotaxin-lysophosphatidic acid receptor signalling regulates hepatitis C virus replication.J Hepatol. 2017 May;66(5):919-929. doi: 10.1016/j.jhep.2017.01.009. Epub 2017 Jan 23.
298 The p7 viroporin of the hepatitis C virus contributes to liver inflammation by stimulating production of Interleukin-1.Biochim Biophys Acta Mol Basis Dis. 2017 Mar;1863(3):712-720. doi: 10.1016/j.bbadis.2016.12.006. Epub 2016 Dec 13.
299 ERAP1 allotypes shape the epitope repertoire of virus-specific CD8(+) T cell responses in acute hepatitis C virus infection.J Hepatol. 2019 Jun;70(6):1072-1081. doi: 10.1016/j.jhep.2019.01.034. Epub 2019 Feb 13.
300 Prevalence and predictors of occult hepatitis C virus infection among Egyptian patients who achieved sustained virologic response to sofosbuvir/daclatasvir therapy: a multi-center study.Infect Drug Resist. 2019 Jan 22;12:273-279. doi: 10.2147/IDR.S181638. eCollection 2019.
301 Contribution of Liver Fibrosis and Microbial Translocation to Immune Activation in Persons Infected With HIV and/or Hepatitis C Virus.J Infect Dis. 2018 Mar 28;217(8):1289-1297. doi: 10.1093/infdis/jix688.
302 Development of an in vitro model to study hepatitis C virus effects on hepatocellular lipotoxicity and lipid metabolism.Pathol Res Pract. 2018 Oct;214(10):1700-1706. doi: 10.1016/j.prp.2018.08.013. Epub 2018 Aug 19.
303 Genetic variants of the IgA Fc receptor (FcalphaR, CD89) promoter in chronic hepatitis C patients.Immunogenetics. 2006 Dec;58(12):937-46. doi: 10.1007/s00251-006-0159-5. Epub 2006 Oct 11.
304 Liver sinusoidal endothelial cells (LSECs) modifications in patients with chronic hepatitis C.Sci Rep. 2019 Jun 19;9(1):8760. doi: 10.1038/s41598-019-45114-1.
305 Hepatitis C virus-induced NK cell activation causes metzincin-mediated CD16 cleavage and impaired antibody-dependent cytotoxicity.J Hepatol. 2017 Jun;66(6):1130-1137. doi: 10.1016/j.jhep.2017.01.032. Epub 2017 Feb 10.
306 Increased cortical expression of FK506 binding protein-51 in HIV-associated neurocognitive disorders.J Neurovirol. 2012 Aug;18(4):313-22. doi: 10.1007/s13365-011-0076-8. Epub 2012 Jan 11.
307 Histological changes in patients who developed hepatocellular carcinoma after hepatitis C virus eradication by interferon-based therapy.Exp Ther Med. 2019 Nov;18(5):3991-4001. doi: 10.3892/etm.2019.8024. Epub 2019 Sep 18.
308 IL28B polymorphisms are associated with severity ofliver disease in human immunodeficiency virus (HIV) patients coinfected with hepatitis C virus.J Infect. 2013 Feb;66(2):170-8. doi: 10.1016/j.jinf.2012.10.025. Epub 2012 Oct 26.
309 Subproteomic study of hepatitis C virus replicon reveals Ras-GTPase-activating protein binding protein 1 as potential HCV RC component.Biochem Biophys Res Commun. 2006 Nov 10;350(1):174-8. doi: 10.1016/j.bbrc.2006.09.027. Epub 2006 Sep 18.
310 Downregulation of Gadd45beta expression by hepatitis C virus leads to defective cell cycle arrest.Cancer Res. 2010 Jun 15;70(12):4901-11. doi: 10.1158/0008-5472.CAN-09-4554. Epub 2010 Jun 8.
311 Expression of alternate reading frame protein (F1) of hepatitis C virus in Escherichia coli and detection of antibodies for F1 in Indian patients.Infect Genet Evol. 2008 May;8(3):374-7. doi: 10.1016/j.meegid.2007.12.008. Epub 2008 Jan 5.
312 Baseline risk factors determine lack of biochemical response after SVR in chronic hepatitis C patients treated with DAAs.Liver Int. 2020 Mar;40(3):539-548. doi: 10.1111/liv.14186. Epub 2019 Jul 25.
313 HCV-RNA and anti-HCV IgM in Egyptian subjects bearing IgG anti-HCV antibodies.Jpn J Infect Dis. 1999 Jun;52(3):113-6.
314 Hepatitis C virus interacts with human platelet glycoprotein VI.J Gen Virol. 2006 Aug;87(Pt 8):2243-2251. doi: 10.1099/vir.0.81826-0.
315 rs2267531, a promoter SNP within glypican-3 gene in the X chromosome, is associated with hepatocellular carcinoma in Egyptians.Sci Rep. 2019 May 3;9(1):6868. doi: 10.1038/s41598-019-43376-3.
316 Lnc-ITM2C-1 and GPR55 Are Proviral Host Factors for Hepatitis C Virus.Viruses. 2019 Jun 13;11(6):549. doi: 10.3390/v11060549.
317 Association of Catalase and Glutathione Peroxidase 1 Polymorphisms with Chronic Hepatitis C Outcome.Ann Hum Genet. 2016 May;80(3):145-53. doi: 10.1111/ahg.12152. Epub 2016 Mar 18.
318 Subversion of cell signaling pathways by hepatitis C virus nonstructural 5A protein via interaction with Grb2 and P85 phosphatidylinositol 3-kinase.J Virol. 2002 Sep;76(18):9207-17. doi: 10.1128/jvi.76.18.9207-9217.2002.
319 Interleukin 27 polymorphisms in HCV RNA positive patients: is there an impact on response to interferon therapy?.BMC Infect Dis. 2014;14 Suppl 5(Suppl 5):S5. doi: 10.1186/1471-2334-14-S5-S5. Epub 2014 Sep 5.
320 A genetic screen identifies interferon- effector genes required to suppress hepatitis C virus replication.Gastroenterology. 2013 Jun;144(7):1438-49, 1449.e1-9. doi: 10.1053/j.gastro.2013.02.026. Epub 2013 Feb 24.
321 Expression of genes involved in lipogenesis is not increased in patients with HCV genotype 3 in human liver.J Viral Hepat. 2011 Jan;18(1):53-60. doi: 10.1111/j.1365-2893.2010.01283.x.
322 Hepatitis C Virus Infection: HostVirus Interaction and Mechanisms of Viral Persistence.Cells. 2019 Apr 25;8(4):376. doi: 10.3390/cells8040376.
323 Structural isomers of cinnamic hydroxamic acids block HCV replication via different mechanisms.Eur J Med Chem. 2019 Dec 1;183:111723. doi: 10.1016/j.ejmech.2019.111723. Epub 2019 Sep 20.
324 Differential association of STAT3 and HK-II expression in hepatitis B virus- and hepatitis C virus-related hepatocellular carcinoma.J Med Virol. 2016 Sep;88(9):1552-9. doi: 10.1002/jmv.24498. Epub 2016 Mar 8.
325 Contradictory intrahepatic immune responses activated in high-load hepatitis C virus livers compared with low-load livers.Arch Virol. 2018 Apr;163(4):855-865. doi: 10.1007/s00705-017-3675-8. Epub 2017 Dec 16.
326 HLA-G and anti-HCV in patients on the waiting list for kidney transplantation.Adv Med Sci. 2018 Sep;63(2):317-322. doi: 10.1016/j.advms.2018.04.004. Epub 2018 Jul 13.
327 Elevated hepatic lipid and interferon stimulated gene expression in HCV GT3 patients relative to non-alcoholic steatohepatitis.Hepatol Int. 2016 Nov;10(6):937-946. doi: 10.1007/s12072-016-9733-6. Epub 2016 May 18.
328 Hepatitis C Virus NS5A Protein Promotes the Lysosomal Degradation of Hepatocyte Nuclear Factor 1 via Chaperone-Mediated Autophagy.J Virol. 2018 Jun 13;92(13):e00639-18. doi: 10.1128/JVI.00639-18. Print 2018 Jul 1.
329 Hepatic Stress Response in HCV Infection Promotes STAT3-Mediated Inhibition of HNF4A-miR-122 Feedback Loop in Liver Fibrosis and Cancer Progression.Cancers (Basel). 2019 Sep 20;11(10):1407. doi: 10.3390/cancers11101407.
330 A 17-Beta-Hydroxysteroid Dehydrogenase 13 Variant Protects From Hepatocellular Carcinoma Development in Alcoholic Liver Disease.Hepatology. 2019 Jul;70(1):231-240. doi: 10.1002/hep.30623. Epub 2019 Apr 25.
331 Heat shock proteins HSPB8 and DNAJC5B have HCV antiviral activity.PLoS One. 2017 Nov 28;12(11):e0188467. doi: 10.1371/journal.pone.0188467. eCollection 2017.
332 Identification of Piperazinylbenzenesulfonamides as New Inhibitors of Claudin-1 Trafficking and Hepatitis C Virus Entry.J Virol. 2018 Apr 27;92(10):e01982-17. doi: 10.1128/JVI.01982-17. Print 2018 May 15.
333 Infection with GB virus C, hepatitis C and B viruses in 1,044 cases autopsied at the Medical Examiner's Office in Tokyo.J Med Virol. 1998 Jun;55(2):123-8.
334 Identification of ID2 associated with invasion of hepatitis C virus-related hepatocellular carcinoma by gene expression profile.Int J Oncol. 2006 Dec;29(6):1445-51.
335 Antiviral and Immunoregulatory Effects of Indoleamine-2,3-Dioxygenase in Hepatitis C Virus Infection.J Innate Immun. 2015;7(5):530-44. doi: 10.1159/000375161. Epub 2015 Mar 19.
336 Hepatitis-C-virus-induced microRNAs dampen interferon-mediated antiviral signaling.Nat Med. 2016 Dec;22(12):1475-1481. doi: 10.1038/nm.4211. Epub 2016 Nov 14.
337 TNF- Induced by Hepatitis C Virus via TLR7 and TLR8 in Hepatocytes Supports Interferon Signaling via an Autocrine Mechanism.PLoS Pathog. 2015 May 29;11(5):e1004937. doi: 10.1371/journal.ppat.1004937. eCollection 2015 May.
338 Evaluation of the relationship between IL28B, IL10RB and IL28RA single-nucleotide polymorphisms and susceptibility to hepatitis C virus in Chinese Han population.Infect Genet Evol. 2014 Jan;21:8-14. doi: 10.1016/j.meegid.2013.10.009. Epub 2013 Oct 19.
339 IL12 Gene Polymorphism in Association with Hepatocellular Carcinoma in HCV-infected Egyptian Patients.Immunol Invest. 2017 Feb;46(2):123-133. doi: 10.1080/08820139.2016.1229789. Epub 2016 Nov 7.
340 IL-15 and IFN- signal through the ERK pathway to inhibit HCV replication, independent of type I IFN signaling.Cytokine. 2019 Dec;124:154439. doi: 10.1016/j.cyto.2018.06.006. Epub 2018 Jun 19.
341 Dysregulation of interferon regulatory factors impairs the expression of immunostimulatory molecules in hepatitis C virus genotype 1-infected hepatocytes.Gut. 2014 Apr;63(4):665-73. doi: 10.1136/gutjnl-2012-304377. Epub 2013 Jun 20.
342 Impact of IL-27p28 (rs153109) and TNF- (rs1800629) Genetic Polymorphisms on the Progression of HCV Infection in Egyptian Patients.Immunol Invest. 2019 Apr;48(3):255-267. doi: 10.1080/08820139.2018.1510958. Epub 2018 Sep 11.
343 Single nucleotide polymorphisms and haplotypes in the IL10 region associated with HCV clearance.Genes Immun. 2005 Jun;6(4):347-57. doi: 10.1038/sj.gene.6364188.
344 Analysis of interleukin (IL)-1beta IL-1 receptor antagonist, soluble IL-1 receptor type II and IL-1 accessory protein in HCV-associated lymphoproliferative disorders.Oncol Rep. 2006 May;15(5):1305-8.
345 Monocytes inhibit hepatitis C virus-induced TRAIL expression on CD56(bright) NK cells.J Hepatol. 2017 Dec;67(6):1148-1156. doi: 10.1016/j.jhep.2017.07.028. Epub 2017 Aug 11.
346 Association of IL-1, IL-1RN, and ESR1 genes polymorphism with risk of infection and response to sofosbuvir plus daclatasvir combination therapy in hepatitis C virus genotype-4 patients.IUBMB Life. 2018 Nov;70(11):1156-1163. doi: 10.1002/iub.1929. Epub 2018 Sep 25.
347 The association between interleukin-21 (rs2055979G/T) gene polymorphism and the risk of hepatocellular carcinoma and metastasis in patients with hepatitis C virus.J Cell Biochem. 2019 Oct;120(10):18524-18532. doi: 10.1002/jcb.29174. Epub 2019 Jun 25.
348 Interleukin-7 Regulates T Follicular Helper Cell Function in Patients with Chronic Hepatitis C.Viral Immunol. 2018 Jul/Aug;31(6):417-425. doi: 10.1089/vim.2018.0010. Epub 2018 Apr 19.
349 Involvement of the Interleukin-23/Interleukin-17 Axis in Chronic Hepatitis C Virus Infection and Its Treatment Responses.Int J Mol Sci. 2016 Jul 15;17(7):1070. doi: 10.3390/ijms17071070.
350 Interleukin-7 augments CD8(+) T cells function and promotes viral clearance in chronic hepatitis C virus infection.Cytokine. 2018 Feb;102:26-33. doi: 10.1016/j.cyto.2017.12.014. Epub 2017 Dec 21.
351 Autoantibodies against "rods and rings"-related IMPDH2 in hepatitis C genotype 1 and DAA therapy in a "real life" cohort.Med Microbiol Immunol. 2017 Oct;206(5):379-382. doi: 10.1007/s00430-017-0516-z. Epub 2017 Aug 16.
352 TRIM27 Promotes Hepatitis C Virus Replication by Suppressing Type I Interferon Response.Inflammation. 2019 Aug;42(4):1317-1325. doi: 10.1007/s10753-019-00992-5.
353 CD2-Associated Protein Contributes to Hepatitis C, Virus Propagation and Steatosis by Disrupting Insulin Signaling.Hepatology. 2018 Nov;68(5):1710-1725. doi: 10.1002/hep.30073.
354 The hepatitis C envelope 2 protein inhibits LFA-1-transduced protein kinase C signaling for T-lymphocyte migration.Gastroenterology. 2006 Feb;130(2):482-92. doi: 10.1053/j.gastro.2005.10.047.
355 NS5A Promotes Constitutive Degradation of IP3R3 to Counteract Apoptosis Induced by Hepatitis C Virus.Cell Rep. 2018 Oct 23;25(4):833-840.e3. doi: 10.1016/j.celrep.2018.09.088.
356 Interferon alpha antagonizes STAT3 and SOCS3 signaling triggered by hepatitis C virus.Cytokine. 2016 Apr;80:48-55. doi: 10.1016/j.cyto.2015.08.264. Epub 2016 Mar 3.
357 Inhibition of miR-148a-3p resists hepatocellular carcinoma progress of hepatitis C virus infection through suppressing c-Jun and MAPK pathway.J Cell Mol Med. 2019 Feb;23(2):1415-1426. doi: 10.1111/jcmm.14045. Epub 2018 Dec 18.
358 Hepatitis C virus core or NS3/4A protein expression preconditions hepatocytes against oxidative stress and endoplasmic reticulum stress.Redox Rep. 2019 Dec;24(1):17-26. doi: 10.1080/13510002.2019.1596431.
359 Stable Frequencies of HLA-C(*)03:04/Peptide-Binding KIR2DL2/3(+) Natural Killer Cells Following Vaccination.Front Immunol. 2018 Oct 17;9:2361. doi: 10.3389/fimmu.2018.02361. eCollection 2018.
360 Human liver-derived CXCR6(+) NK cells are predominantly educated through NKG2A and show reduced cytokine production.J Leukoc Biol. 2019 Jun;105(6):1331-1340. doi: 10.1002/JLB.1MA1118-428R. Epub 2019 Feb 19.
361 KLRG1 impairs CD4+ T cell responses via p16ink4a and p27kip1 pathways: role in hepatitis B vaccine failure in individuals with hepatitis C virus infection.J Immunol. 2014 Jan 15;192(2):649-57. doi: 10.4049/jimmunol.1302069. Epub 2013 Dec 13.
362 HBsAg stimulates NKG2D receptor expression on natural killer cells and inhibits hepatitis C virus replication.Hepatobiliary Pancreat Dis Int. 2018 Jun;17(3):233-240. doi: 10.1016/j.hbpd.2018.03.010. Epub 2018 Mar 26.
363 Elevated LAG-3 on CD4(+) T cells negatively correlates with neutralizing antibody response during HCV infection.Immunol Lett. 2019 Aug;212:46-52. doi: 10.1016/j.imlet.2019.06.003. Epub 2019 Jun 16.
364 Inhibitory molecules that regulate expansion and restoration of HCV-specific CD4+ T cells in patients with chronic infection.Gastroenterology. 2011 Oct;141(4):1422-31, 1431.e1-6. doi: 10.1053/j.gastro.2011.07.004. Epub 2011 Jul 18.
365 Modulation of Hepatitis C Virus-Specific CD8 Effector T-Cell Function with Antiviral Effect in Infectious Hepatitis C Virus Coculture Model.J Virol. 2017 Apr 28;91(10):e02129-16. doi: 10.1128/JVI.02129-16. Print 2017 May 15.
366 Impaired allostimulatory capacity of peripheral blood dendritic cells recovered from hepatitis C virus-infected individuals.J Immunol. 1999 May 1;162(9):5584-91.
367 Expression signature of lysosomal-associated transmembrane protein 4B in hepatitis C virus-induced hepatocellular carcinoma.Int J Biol Markers. 2018 Aug;33(3):283-292. doi: 10.1177/1724600818773631. Epub 2018 Jun 8.
368 LARP1 binding to hepatitis C virus particles is correlated with intracellular retention of viral infectivity.Virus Res. 2019 Oct 2;271:197679. doi: 10.1016/j.virusres.2019.197679. Epub 2019 Aug 6.
369 Direct binding of hepatitis C virus core to gC1qR on CD4+ and CD8+ T cells leads to impaired activation of Lck and Akt.J Virol. 2004 Jun;78(12):6409-19. doi: 10.1128/JVI.78.12.6409-6419.2004.
370 A Relative Deficiency of Lysosomal Acid Lypase Activity Characterizes Non-Alcoholic Fatty Liver Disease.Int J Mol Sci. 2017 May 25;18(6):1134. doi: 10.3390/ijms18061134.
371 Abnormal deposition of collagen around hepatocytes in Wilson's disease is associated with hepatocyte specific expression of lysyl oxidase and lysyl oxidase like protein-2. J Hepatol. 2005 Sep;43(3):499-507. doi: 10.1016/j.jhep.2005.02.052.
372 The intracellular inhibition of HCV replication represents a novel mechanism of action by the innate immune Lactoferrin protein.Antiviral Res. 2014 Nov;111:13-22. doi: 10.1016/j.antiviral.2014.08.012. Epub 2014 Sep 1.
373 Priming with two DNA vaccines expressing hepatitis C virus NS3 protein targeting dendritic cells elicits superior heterologous protective potential in mice.Arch Virol. 2015 Oct;160(10):2517-24. doi: 10.1007/s00705-015-2535-7. Epub 2015 Jul 28.
374 The expression of the hepatocyte SLAMF3 (CD229) receptor enhances the hepatitis C virus infection.PLoS One. 2014 Jun 13;9(6):e99601. doi: 10.1371/journal.pone.0099601. eCollection 2014.
375 MAGE-3 and MAGE-4 genes as possible markers for early detection of metastases in hepatitis C virus Egyptian patients complicated by hepatocellular carcinoma.Med Oncol. 2012 Jun;29(2):994-9. doi: 10.1007/s12032-011-9917-9. Epub 2011 Mar 31.
376 Hepatitis C virus NS5A inhibits mixed lineage kinase 3 to block apoptosis.J Biol Chem. 2013 Aug 23;288(34):24753-63. doi: 10.1074/jbc.M113.491985. Epub 2013 Jul 15.
377 Pretreatment serum macrophage inflammatory protein (MIP)-1 levels predict sustained virological responses to re-treatment in patients with chronic hepatitis C virus infection.Int J Infect Dis. 2015 Apr;33:15-21. doi: 10.1016/j.ijid.2014.08.021. Epub 2014 Oct 24.
378 A polymorphism in MAPKAPK3 affects response to interferon therapy for chronic hepatitis C.Gastroenterology. 2009 May;136(5):1796-805.e6. doi: 10.1053/j.gastro.2009.01.061. Epub 2009 Jan 31.
379 The kinase inhibitor SFV785 dislocates dengue virus envelope protein from the replication complex and blocks virus assembly.PLoS One. 2011;6(8):e23246. doi: 10.1371/journal.pone.0023246. Epub 2011 Aug 17.
380 Expression of immunoreactive forms of the hepatitis C NS5A protein in E. coli and their use for diagnostic assays.Arch Virol. 2002 Sep;147(9):1733-45. doi: 10.1007/s00705-002-0836-0.
381 Association of hepatitis C virus infection and malnutrition-inflammation complex syndrome in maintenance hemodialysis patients.Nephrol Dial Transplant. 2012 Mar;27(3):1176-83. doi: 10.1093/ndt/gfr458. Epub 2011 Sep 5.
382 Development of a Method That Delivers Drugs to Enveloped Viruses.Biol Pharm Bull. 2019;42(6):977-981. doi: 10.1248/bpb.b18-01000.
383 Association between hepatic steatosis and MTP gene -493G/T polymorphism in the patients with HCV genotype 1 infection.Infect Genet Evol. 2019 Jun;70:101-106. doi: 10.1016/j.meegid.2019.02.019. Epub 2019 Feb 18.
384 Platelet count increases after viral elimination in chronic HCV, independent of the presence or absence of cirrhosis.Liver Int. 2019 Nov;39(11):2061-2065. doi: 10.1111/liv.14203. Epub 2019 Aug 21.
385 CD56-negative NK cells with impaired effector function expand in CMV and EBV co-infected healthy donors with age.Aging (Albany NY). 2019 Jan 27;11(2):724-740. doi: 10.18632/aging.101774.
386 Functional Behavior of NKp46-Positive Intrahepatic Natural Killer Cells Against Hepatitis C Virus Reinfection After Liver Transplantation.Transplantation. 2016 Feb;100(2):355-64. doi: 10.1097/TP.0000000000001031.
387 Functional and topological properties in hepatocellular carcinoma transcriptome.PLoS One. 2012;7(4):e35510. doi: 10.1371/journal.pone.0035510. Epub 2012 Apr 23.
388 NLRX1 Mediates MAVS Degradation To Attenuate the Hepatitis C Virus-Induced Innate Immune Response through PCBP2.J Virol. 2017 Nov 14;91(23):e01264-17. doi: 10.1128/JVI.01264-17. Print 2017 Dec 1.
389 Notch4 and mhc class II polymorphisms are associated with hcv-related benign and malignant lymphoproliferative diseases.Oncotarget. 2017 May 6;8(42):71528-71535. doi: 10.18632/oncotarget.17655. eCollection 2017 Sep 22.
390 A natural small molecule inhibitor corilagin blocks HCV replication and modulates oxidative stress to reduce liver damage.Antiviral Res. 2018 Feb;150:47-59. doi: 10.1016/j.antiviral.2017.12.004. Epub 2017 Dec 7.
391 Genetic variations of the NPC1L1 gene associated with hepatitis C virus (HCV) infection and biochemical characteristics of HCV patients in China.Int J Infect Dis. 2016 Dec;53:6-11. doi: 10.1016/j.ijid.2016.10.007. Epub 2016 Oct 18.
392 The metabolic regulator small heterodimer partner contributes to the glucose and lipid homeostasis abnormalities induced by hepatitis C virus infection.Metabolism. 2019 Nov;100:153954. doi: 10.1016/j.metabol.2019.153954. Epub 2019 Aug 8.
393 Genome-Wide Association Study Identifies Risk Variants for Lichen Planus in Patients With Hepatitis C Virus Infection.Clin Gastroenterol Hepatol. 2017 Jun;15(6):937-944.e5. doi: 10.1016/j.cgh.2016.12.029. Epub 2017 Jan 5.
394 Molecular diagnosis of occult hepatitis C virus infection in Iranian injection drug users.Arch Virol. 2019 Feb;164(2):349-357. doi: 10.1007/s00705-018-4066-5. Epub 2018 Nov 2.
395 The AMPK-related kinase SNARK regulates hepatitis C virus replication and pathogenesis through enhancement of TGF- signaling.J Hepatol. 2013 Nov;59(5):942-8. doi: 10.1016/j.jhep.2013.06.025. Epub 2013 Jul 2.
396 micro-Opioid receptor activation prevents acute hepatic inflammation and cell death.Gut. 2007 Jul;56(7):974-81. doi: 10.1136/gut.2006.105122. Epub 2007 Feb 13.
397 Identification of ionotrophic purinergic receptors in Huh-7 cells and their response towards structural proteins of HCV genotype 3a.Virol J. 2011 Sep 8;8:431. doi: 10.1186/1743-422X-8-431.
398 The PD-1/PD-L1 Axis and Virus Infections: A Delicate Balance.Front Cell Infect Microbiol. 2019 Jun 13;9:207. doi: 10.3389/fcimb.2019.00207. eCollection 2019.
399 The SR-BI partner PDZK1 facilitates hepatitis C virus entry.PLoS Pathog. 2010 Oct 7;6(10):e1001130. doi: 10.1371/journal.ppat.1001130.
400 CXC chemokine ligand 4 (Cxcl4) is a platelet-derived mediator of experimental liver fibrosis.Hepatology. 2010 Apr;51(4):1345-53. doi: 10.1002/hep.23435.
401 Hepatitis C Virus Subverts Human Choline Kinase- To Bridge Phosphatidylinositol-4-Kinase III (PI4KIII) and NS5A and Upregulates PI4KIII Activation, Thereby Promoting the Translocation of the Ternary Complex to the Endoplasmic Reticulum for Viral Replication.J Virol. 2017 Jul 27;91(16):e00355-17. doi: 10.1128/JVI.00355-17. Print 2017 Aug 15.
402 Activity-Based Phosphatidylinositol Kinase Probes Detect Changes to Protein-Protein Interactions During Hepatitis C Virus Replication.ACS Infect Dis. 2018 May 11;4(5):752-757. doi: 10.1021/acsinfecdis.8b00047. Epub 2018 Mar 14.
403 Up-regulation of proproliferative genes and the ligand/receptor pair placental growth factor and vascular endothelial growth factor receptor 1 in hepatitis C cirrhosis.Liver Int. 2007 Sep;27(7):960-8. doi: 10.1111/j.1478-3231.2007.01542.x.
404 The lipid droplet-associated protein perilipin 3 facilitates hepatitis C virus-driven hepatic steatosis.J Lipid Res. 2017 Feb;58(2):420-432. doi: 10.1194/jlr.M073734. Epub 2016 Dec 10.
405 The ribonuclease L-dependent antiviral roles of human 2',5'-oligoadenylate synthetase family members against hepatitis C virus.FEBS Lett. 2013 Jan 16;587(2):156-64. doi: 10.1016/j.febslet.2012.11.010. Epub 2012 Nov 26.
406 Hepatitis C virus core protein modulates several signaling pathways involved in hepatocellular carcinoma.World J Gastroenterol. 2019 Jan 7;25(1):42-58. doi: 10.3748/wjg.v25.i1.42.
407 Human MxB Inhibits the Replication of Hepatitis C Virus.J Virol. 2018 Dec 10;93(1):e01285-18. doi: 10.1128/JVI.01285-18. Print 2019 Jan 1.
408 Cyclophilin B facilitates the replication of Orf virus.Virol J. 2017 Jun 15;14(1):114. doi: 10.1186/s12985-017-0781-x.
409 Hepatitis C virus NS3 protein enhances hepatocellular carcinoma cell invasion by promoting PPM1A ubiquitination and degradation.J Exp Clin Cancer Res. 2017 Mar 10;36(1):42. doi: 10.1186/s13046-017-0510-8.
410 Emerging viral STIs among HIV-positive men who have sex with men: the era of hepatitis C virus and human papillomavirus.Sex Transm Infect. 2017 Aug;93(5):368-373. doi: 10.1136/sextrans-2016-052677. Epub 2016 Oct 27.
411 Arterial thrombosis in the context of HCV-associated vascular disease can be prevented by protein C.Cell Mol Immunol. 2017 Dec;14(12):986-996. doi: 10.1038/cmi.2016.10. Epub 2016 Apr 18.
412 Mannan binding lectin-associated serine protease 1 is induced by hepatitis C virus infection and activates human hepatic stellate cells.Clin Exp Immunol. 2013 Nov;174(2):265-73. doi: 10.1111/cei.12174.
413 MEAN inhibits hepatitis C virus replication by interfering with a polypyrimidine tract-binding protein.J Cell Mol Med. 2016 Jul;20(7):1255-65. doi: 10.1111/jcmm.12798. Epub 2016 Mar 1.
414 Suppression of dual specificity phosphatase I expression inhibits hepatitis C virus replication.PLoS One. 2015 Mar 23;10(3):e0119172. doi: 10.1371/journal.pone.0119172. eCollection 2015.
415 Interferon alpha treatment stimulates interferon gamma expression in type I NKT cells and enhances their antiviral effect against hepatitis C virus.PLoS One. 2017 Mar 2;12(3):e0172412. doi: 10.1371/journal.pone.0172412. eCollection 2017.
416 Hepatitis C virus promotes virion secretion through cleavage of the Rab7 adaptor protein RILP.Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):12484-12489. doi: 10.1073/pnas.1607277113. Epub 2016 Oct 17.
417 RACK1 mediates rewiring of intracellular networks induced by hepatitis C virus infection.PLoS Pathog. 2019 Sep 16;15(9):e1008021. doi: 10.1371/journal.ppat.1008021. eCollection 2019 Sep.
418 RECK Gene Promoter rs10814325 Polymorphism in Egyptian Patients with Hepatocellular Carcinoma on Top of Chronic Hepatitis C Viral Infection.Asian Pac J Cancer Prev. 2016;17(5):2383-8.
419 Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection.Gastroenterology. 2012 Nov;143(5):1244-1252.e12. doi: 10.1053/j.gastro.2012.07.097. Epub 2012 Jul 27.
420 Polymorphisms in the Th17 cell-related RORC gene are associated with spontaneous clearance of HCV in Chinese women.BMC Infect Dis. 2018 Jun 4;18(1):254. doi: 10.1186/s12879-018-3153-2.
421 Condomless sex in HIV-diagnosed men who have sex with men in the UK: prevalence, correlates, and implications for HIV transmission.Sex Transm Infect. 2017 Dec;93(8):590-598. doi: 10.1136/sextrans-2016-053029. Epub 2017 Jul 5.
422 Ribonucleotide reductase M2 promotes RNA replication of hepatitis C virus by protecting NS5B protein from hPLIC1-dependent proteasomal degradation.J Biol Chem. 2019 Apr 12;294(15):5759-5773. doi: 10.1074/jbc.RA118.004397. Epub 2019 Feb 12.
423 Hepatitis C virus Core overcomes all-trans retinoic acid-induced apoptosis in human hepatoma cells by inhibiting p14 expression via DNA methylation.Oncotarget. 2017 Aug 18;8(49):85584-85598. doi: 10.18632/oncotarget.20337. eCollection 2017 Oct 17.
424 Syndecan-1 in Liver Diseases.Pathol Oncol Res. 2020 Apr;26(2):813-819. doi: 10.1007/s12253-019-00617-0. Epub 2019 Mar 2.
425 Attachment and Postattachment Receptors Important for Hepatitis C Virus Infection and Cell-to-Cell Transmission.J Virol. 2017 Jun 9;91(13):e00280-17. doi: 10.1128/JVI.00280-17. Print 2017 Jul 1.
426 Set7 facilitates hepatitis C virus replication via enzymatic activity-dependent attenuation of the IFN-related pathway.J Immunol. 2015 Mar 15;194(6):2757-68. doi: 10.4049/jimmunol.1400583. Epub 2015 Feb 13.
427 Sigma-1 receptor regulates early steps of viral RNA replication at the onset of hepatitis C virus infection.J Virol. 2013 Jun;87(11):6377-90. doi: 10.1128/JVI.03557-12. Epub 2013 Mar 27.
428 A Novel Tricyclic Polyketide, Vanitaracin A, Specifically Inhibits the Entry of Hepatitis B and D Viruses by Targeting Sodium Taurocholate Cotransporting Polypeptide.J Virol. 2015 Dec;89(23):11945-53. doi: 10.1128/JVI.01855-15. Epub 2015 Sep 16.
429 Immunoreactive core peptides of hepatitis C virus produced in Escherichia coli and in vitro DNA amplification-restricted transcription-translation system.J Virol Methods. 1996 May;59(1-2):91-8. doi: 10.1016/0166-0934(96)02025-3.
430 Hepatitis B virus reactivation during direct-acting antiviral therapy for hepatitis C: a systematic review and meta-analysis.Lancet Gastroenterol Hepatol. 2018 Mar;3(3):172-180. doi: 10.1016/S2468-1253(18)30002-5. Epub 2018 Jan 19.
431 Management of HCV-related decompensated cirrhosis with direct-acting antiviral agents: who should be treated?.Hepatol Int. 2019 Mar;13(2):165-172. doi: 10.1007/s12072-019-09933-8. Epub 2019 Feb 13.
432 Role of ITPA and SLC28A2 genes in the prediction of anaemia associated with protease inhibitor plus ribavirin and peginterferon in hepatitis C treatment. J Clin Virol. 2015 Jul;68:56-60.
433 SLC29A1 polymorphism and prediction of anaemia severity in patients with chronic hepatitis C receiving triple therapy with telaprevir.J Antimicrob Chemother. 2015 Apr;70(4):1155-60. doi: 10.1093/jac/dku519. Epub 2015 Jan 11.
434 SLC30A8 rs13266634 polymorphism is related to a favorable cardiometabolic lipid profile in HIV/hepatitis C virus-coinfected patients.AIDS. 2014 Jun 1;28(9):1325-32. doi: 10.1097/QAD.0000000000000215.
435 Hepatitis C Virus Modulates Solute carrier family 3 member 2 for Viral Propagation.Sci Rep. 2018 Oct 19;8(1):15486. doi: 10.1038/s41598-018-33861-6.
436 Monoclonal antibody 2-152a suppresses hepatitis C virus infection through betaine/GABA transporter-1.J Infect Dis. 2011 Oct 15;204(8):1172-80. doi: 10.1093/infdis/jir501.
437 Elucidating the Plasma and Liver Pharmacokinetics of Simeprevir in Special Populations Using Physiologically Based Pharmacokinetic Modelling.Clin Pharmacokinet. 2017 Jul;56(7):781-792. doi: 10.1007/s40262-016-0476-2.
438 Hepatitis C Virus Core Protein Modulates Endoglin (CD105) Signaling Pathway for Liver Pathogenesis.J Virol. 2017 Oct 13;91(21):e01235-17. doi: 10.1128/JVI.01235-17. Print 2017 Nov 1.
439 The potential regulatory role of miR16 to the interplay between interferon and transforming growth factor beta pathways through IRF3 and SMAD7 in hepatitis C virus infected patients.J Cell Biochem. 2019 Aug;120(8):12694-12701. doi: 10.1002/jcb.28537. Epub 2019 Mar 12.
440 Interaction of the hepatitis B virus X protein with the lysine methyltransferase SET and MYND domain-containing 3 induces activator protein 1 activation.Microbiol Immunol. 2016 Jan;60(1):17-25. doi: 10.1111/1348-0421.12345.
441 Phosphorylated tyrosine 93 of hepatitis C virus nonstructural protein 5A is essential for interaction with host c-Src and efficient viral replication.J Biol Chem. 2019 May 3;294(18):7388-7402. doi: 10.1074/jbc.RA119.007656. Epub 2019 Mar 12.
442 Etifoxine, a TSPO Ligand, Worsens Hepatitis C-Related Insulin Resistance but Relieves Lipid Accumulation.Biomed Res Int. 2019 Mar 11;2019:3102414. doi: 10.1155/2019/3102414. eCollection 2019.
443 HCV and flaviviruses hijack cellular mechanisms for nuclear STAT2 degradation: Up-regulation of PDLIM2 suppresses the innate immune response.PLoS Pathog. 2019 Aug 2;15(8):e1007949. doi: 10.1371/journal.ppat.1007949. eCollection 2019 Aug.
444 Upregulation of major histocompatibility complex class I on liver cells by hepatitis C virus core protein via p53 and TAP1 impairs natural killer cell cytotoxicity.J Virol. 2003 Aug;77(15):8299-309. doi: 10.1128/jvi.77.15.8299-8309.2003.
445 Increased genomic instability following treatment with direct acting anti-hepatitis C virus drugs.EBioMedicine. 2018 Sep;35:106-113. doi: 10.1016/j.ebiom.2018.08.007. Epub 2018 Aug 20.
446 Inhibition of TRF2 accelerates telomere attrition and DNA damage in nave CD4 T cells during HCV infection.Cell Death Dis. 2018 Sep 5;9(9):900. doi: 10.1038/s41419-018-0897-y.
447 Negative Correlation Between Hepatitis C Virus (HCV) and Let-7 MicroRNA Family in Transplanted Livers: The Role of rs868 Single-Nucleotide Polymorphism.Ann Transplant. 2017 Oct 24;22:638-645. doi: 10.12659/aot.905540.
448 Beyond immune thrombocytopenia: the evolving role of thrombopoietin receptor agonists.Ann Hematol. 2017 Sep;96(9):1421-1434. doi: 10.1007/s00277-017-2953-6. Epub 2017 Mar 8.
449 Correction: Hepatitis C virus NS4B induces the degradation of TRIF to inhibit TLR3-mediated interferon signaling pathway.PLoS Pathog. 2018 Nov 16;14(11):e1007455. doi: 10.1371/journal.ppat.1007455. eCollection 2018 Nov.
450 Clinical Significance of Polymorphisms in Immune Response Genes in Hepatitis C-Related Hepatocellular Carcinoma.Front Microbiol. 2019 Mar 15;10:475. doi: 10.3389/fmicb.2019.00475. eCollection 2019.
451 TLR3 and TLR4 SNP variants in the liver disease resulting from hepatitis B virus and hepatitis C virus infection.Br J Biomed Sci. 2019 Jan;76(1):35-41. doi: 10.1080/09674845.2018.1547179. Epub 2018 Dec 3.
452 Toll-like receptors 1 and 6 are involved in TLR2-mediated macrophage activation by hepatitis C virus core and NS3 proteins.J Leukoc Biol. 2007 Sep;82(3):479-87. doi: 10.1189/jlb.0207128. Epub 2007 Jun 26.
453 Genetic variations in toll-like receptors 7 and 8 modulate natural hepatitis C outcomes and liver disease progression.Liver Int. 2018 Mar;38(3):432-442. doi: 10.1111/liv.13533. Epub 2017 Aug 24.
454 TLR9 signalling in HCV-associated atypical memory B cells triggers Th1 and rheumatoid factor autoantibody responses.J Hepatol. 2019 Nov;71(5):908-919. doi: 10.1016/j.jhep.2019.06.029. Epub 2019 Jul 4.
455 PNPLA3 and TM6SF2 variants as risk factors of hepatocellular carcinoma across various etiologies and severity of underlying liver diseases.Int J Cancer. 2019 Feb 1;144(3):533-544. doi: 10.1002/ijc.31910. Epub 2018 Nov 9.
456 Evaluation of alternative serum biomarkers to monitor the progression of chronic HBV and HCV infection.Infect Genet Evol. 2018 Mar;58:17-22. doi: 10.1016/j.meegid.2017.12.002. Epub 2017 Dec 6.
457 Hepatitis C Virus Exploits Death Receptor 6-mediated Signaling Pathway to Facilitate Viral Propagation.Sci Rep. 2017 Jul 25;7(1):6445. doi: 10.1038/s41598-017-06740-9.
458 Haplotype HLA-B8-DR3 confers susceptibility to hepatitis C virus-related mixed cryoglobulinemia.Blood. 1998 Mar 15;91(6):2062-6.
459 A single nucleotide polymorphism in activated Cdc42 associated tyrosine kinase 1 influences the interferon therapy in hepatitis C patients.J Hepatol. 2011 Apr;54(4):629-39. doi: 10.1016/j.jhep.2010.07.021. Epub 2010 Nov 18.
460 Online symptom checker diagnostic and triage accuracy for HIV and hepatitis C.Epidemiol Infect. 2019 Jan;147:e104. doi: 10.1017/S0950268819000268.
461 GP73 represses host innate immune response to promote virus replication by facilitating MAVS and TRAF6 degradation.PLoS Pathog. 2017 Apr 10;13(4):e1006321. doi: 10.1371/journal.ppat.1006321. eCollection 2017 Apr.
462 HIV and HCV augments inflammatory responses through increased TREM-1 expression and signaling in Kupffer and Myeloid cells.PLoS Pathog. 2019 Jul 1;15(7):e1007883. doi: 10.1371/journal.ppat.1007883. eCollection 2019 Jul.
463 Clemizole hydrochloride blocks cardiac potassium currents stably expressed in HEK 293 cells.Br J Pharmacol. 2017 Feb;174(3):254-266. doi: 10.1111/bph.13679. Epub 2017 Jan 12.
464 Activation of hepatic stellate cells by the ubiquitin C-terminal hydrolase 1 protein secreted from hepatitis C virus-infected hepatocytes.Sci Rep. 2017 Jun 30;7(1):4448. doi: 10.1038/s41598-017-04259-7.
465 E6AP goes viral: the role of E6AP in viral- and non-viral-related cancers.Carcinogenesis. 2019 Jul 6;40(6):707-714. doi: 10.1093/carcin/bgz072.
466 Marijuana Use Is Not Associated With Progression to Advanced Liver Fibrosis in HIV/Hepatitis C Virus-coinfected Women.Clin Infect Dis. 2016 Aug 15;63(4):512-8. doi: 10.1093/cid/ciw350. Epub 2016 May 25.
467 Hepatitis C Virus NS3 Protein Plays a Dual Role in WRN-Mediated Repair of Nonhomologous End Joining.J Virol. 2019 Oct 29;93(22):e01273-19. doi: 10.1128/JVI.01273-19. Print 2019 Nov 15.
468 Analysis of Lamin B1, Vimentin and Anti-Ku86 as Prospective Biomarkers of Hepatocellular Carcinoma in Patients with Hepatitis C Virus Infection.Cell Physiol Biochem. 2019;52(3):595-605. doi: 10.33594/000000042.
469 Barriers to Hepatitis C Screening in a Minority Population: A Comparison of Hepatitis C and Human Immunodeficiency Virus Screening Rates at a Community STD Clinic in Miami, Florida.J Community Health. 2017 Oct;42(5):921-925. doi: 10.1007/s10900-017-0335-6.
470 Relationship of genetic polymorphisms in CTLA-4 and IL-18 with viral hepatitis: evidence from a meta-analysis.Epidemiol Infect. 2019 Dec 5;147:e313. doi: 10.1017/S0950268819001997.
471 The machinery for endocytosis of epidermal growth factor receptor coordinates the transport of incoming hepatitis B virus to the endosomal network.J Biol Chem. 2020 Jan 17;295(3):800-807. doi: 10.1074/jbc.AC119.010366. Epub 2019 Dec 12.
472 High MELD score does not adversely affect outcome of living donor liver transplantation: Experience in 1000 recipients.Clin Transplant. 2017 Aug;31(8). doi: 10.1111/ctr.13006.
473 Efficacy and Pharmacokinetics of Glecaprevir and Pibrentasvir With Concurrent Use of Acid-Reducing Agents in Patients With Chronic HCV Infection.Clin Gastroenterol Hepatol. 2019 Feb;17(3):527-535.e6. doi: 10.1016/j.cgh.2018.07.003. Epub 2018 Sep 10.
474 Increased Risk of Death in First Year After Liver Transplantation Among Patients With Nonalcoholic Steatohepatitis vs Liver Disease of Other Etiologies.Clin Gastroenterol Hepatol. 2019 Dec;17(13):2759-2768.e5. doi: 10.1016/j.cgh.2019.04.033. Epub 2019 Apr 17.
475 Association of genetic variants in estrogen receptor with HCV infection susceptibility and viral clearance in a high-risk Chinese population.Eur J Clin Microbiol Infect Dis. 2014 Jun;33(6):999-1010. doi: 10.1007/s10096-013-2038-y. Epub 2014 Jan 7.
476 Single and combined IL28B, ITPA and SLC28A3 host genetic markers modulating response to anti-hepatitis C therapy.Pharmacogenomics. 2011 Dec;12(12):1729-40. doi: 10.2217/pgs.11.99.
477 Role of nucleoside transporters SLC28A2/3 and SLC29A1/2 genetics in ribavirin therapy: protection against anemia in patients with chronic hepatitis C.Pharmacogenet Genomics. 2011 May;21(5):289-96. doi: 10.1097/FPC.0b013e32834412e7.
478 UGT1A1*28 relationship with abnormal total bilirubin levels in chronic hepatitis C patients: Outcomes from a case-control study.Medicine (Baltimore). 2017 Mar;96(11):e6306. doi: 10.1097/MD.0000000000006306.
479 Different Hepatitis C Virus Infection Statuses Show a Significant Risk of Developing Type 2 Diabetes Mellitus: A Network Meta-Analysis.Dig Dis Sci. 2020 Jul;65(7):1940-1950. doi: 10.1007/s10620-019-05918-7. Epub 2019 Nov 23.
480 The haplotype block, NFKBIL1-ATP6V1G2-BAT1-MICB-MICA, within the class III-class I boundary region of the human major histocompatibility complex may control susceptibility to hepatitis C virus-associated dilated cardiomyopathy.Tissue Antigens. 2005 Sep;66(3):200-8. doi: 10.1111/j.1399-0039.2005.00457.x.
481 Degradation of AIMP1/p43 induced by hepatitis C virus E2 leads to upregulation of TGF- signaling and increase in surface expression of gp96.PLoS One. 2014 May 9;9(5):e96302. doi: 10.1371/journal.pone.0096302. eCollection 2014.
482 Impact of aldo-keto reductase family 1 member B10 on the risk of hepatitis C virus-related hepatocellular carcinoma.J Gastroenterol Hepatol. 2016 Jul;31(7):1315-22. doi: 10.1111/jgh.13295.
483 Vitamin D-related gene polymorphism predict treatment response to pegylated interferon-based therapy in Thai chronic hepatitis C patients.BMC Gastroenterol. 2017 Apr 17;17(1):54. doi: 10.1186/s12876-017-0613-x.
484 Caught before Released: Structural Mapping of the Reaction Trajectory for the Sofosbuvir Activating Enzyme, Human Histidine Triad Nucleotide Binding Protein 1 (hHint1).Biochemistry. 2017 Jul 18;56(28):3559-3570. doi: 10.1021/acs.biochem.7b00148. Epub 2017 Jul 10.
485 Association Between Combined Presence of Hepatitis C Virus and Polymorphisms in Different Genes With Toxicities of Methotrexate and 6-Mercaptopurine in Children With Acute Lymphoblastic Leukemia.Pediatr Blood Cancer. 2016 Sep;63(9):1539-45. doi: 10.1002/pbc.26045. Epub 2016 May 10.
486 UDP-glucuronosyltransferase 1A7 polymorphisms are associated with liver cirrhosis.Biochem Biophys Res Commun. 2008 Feb 15;366(3):643-8. doi: 10.1016/j.bbrc.2007.11.125. Epub 2007 Dec 3.
487 Application of a Waveguide-Mode Sensor to Blood Testing for Hepatitis B Virus, Hepatitis C Virus, Human Immunodeficiency Virus and Treponema pallidum Infection.Sensors (Basel). 2019 Apr 11;19(7):1729. doi: 10.3390/s19071729.
488 Endogenous levels of mRNA for IFNs and IFN-related genes in hepatic biopsies of chronic HCV-infected and non-alcoholic steatohepatitis patients.J Med Virol. 2003 Aug;70(4):581-7. doi: 10.1002/jmv.10433.
489 Impact of CYP2R1, CYP27A1 and CYP27B1 genetic polymorphisms controlling vitamin D metabolism on susceptibility to hepatitis C virus infection in a high-risk Chinese population.Arch Virol. 2019 Dec;164(12):2909-2918. doi: 10.1007/s00705-019-04378-8. Epub 2019 Sep 13.
490 Determinants of the variability of aflatoxin-albumin adduct levels in Ghanaians.J Toxicol Environ Health A. 2007 Jan;70(1):58-66. doi: 10.1080/15287390600748880.
491 Early viral and peripheral blood mononuclear cell responses to pegylated interferon and ribavirin treatment: the first 24h.Eur J Gastroenterol Hepatol. 2010 Oct;22(10):1211-20. doi: 10.1097/MEG.0b013e32833caf7b.
492 Interleukin-28B polymorphisms are associated with hepatitis C virus clearance and viral load in a HIV-1-infected cohort.J Viral Hepat. 2011 Apr;18(4):e66-74. doi: 10.1111/j.1365-2893.2010.01392.x. Epub 2010 Nov 12.
493 Hepatitis C virus alters metabolism of biogenic polyamines by affecting expression of key enzymes of their metabolism.Biochem Biophys Res Commun. 2017 Feb 5;483(2):904-909. doi: 10.1016/j.bbrc.2017.01.032. Epub 2017 Jan 9.
494 Expression analysis of THOP1 in background liver, a prognostic predictive factor in hepatocellular carcinoma, extracted by multiarray analysis.Ann Surg Oncol. 2014 Jun;21 Suppl 3:S443-50. doi: 10.1245/s10434-014-3581-1. Epub 2014 Mar 7.
495 Dendritic cell function during chronic hepatitis C virus and human immunodeficiency virus type 1 infection.Clin Vaccine Immunol. 2007 Sep;14(9):1127-37. doi: 10.1128/CVI.00141-07. Epub 2007 Jul 18.
496 AGA Clinical Practice Update on Interaction Between Oral Direct-Acting Antivirals for Chronic Hepatitis C Infection and Hepatocellular Carcinoma: Expert Review.Gastroenterology. 2019 Jun;156(8):2149-2157. doi: 10.1053/j.gastro.2019.02.046. Epub 2019 Mar 13.
497 Investigation of the role of GBF1 in the replication of positive-sense single-stranded RNA viruses.J Gen Virol. 2018 Aug;99(8):1086-1096. doi: 10.1099/jgv.0.001099. Epub 2018 Jun 20.
498 Hepatitis C virus NS5A protein interacts with beta-catenin and stimulates its transcriptional activity in a phosphoinositide-3 kinase-dependent fashion.J Gen Virol. 2010 Feb;91(Pt 2):373-81. doi: 10.1099/vir.0.015305-0. Epub 2009 Oct 21.
499 Long noncoding RNA #32 contributes to antiviral responses by controlling interferon-stimulated gene expression.Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):10388-93. doi: 10.1073/pnas.1525022113. Epub 2016 Aug 31.
500 LC3B is not recruited along with the autophagy elongation complex (ATG5-12/16L1) at HCV replication site and is dispensable for viral replication.PLoS One. 2018 Oct 4;13(10):e0205189. doi: 10.1371/journal.pone.0205189. eCollection 2018.
501 Augmentation of hepatitis C virus-specific immunity and sustained virologic response.J Viral Hepat. 2017 Sep;24(9):742-749. doi: 10.1111/jvh.12702. Epub 2017 May 4.
502 Comparison of conventional PCR with real-time PCR and branched DNA-based assays for hepatitis C virus RNA quantification and clinical significance for genotypes 1 to 5.J Clin Microbiol. 2006 Mar;44(3):729-37. doi: 10.1128/JCM.44.3.729-737.2006.
503 Semiquantitative analysis of intrahepatic CC-chemokine mRNas in chronic hepatitis C.Mediators Inflamm. 2004 Dec;13(5-6):357-9. doi: 10.1080/09629350400003159.
504 Can tobacco use promote HCV-induced miR-122 hijacking and hepatocarcinogenesis?.Med Hypotheses. 2013 Feb;80(2):131-3. doi: 10.1016/j.mehy.2012.11.009. Epub 2012 Dec 5.
505 KAI1, a prostate metastasis suppressor: prediction of solvated structure and interactions with binding partners; integrins, cadherins, and cell-surface receptor proteins.Mol Carcinog. 2001 Nov;32(3):139-53. doi: 10.1002/mc.1073.
506 Cyclic adenosine monophosphate response element-binding protein transcriptionally regulates CHCHD2 associated with the molecular pathogenesis of hepatocellular carcinoma.Mol Med Rep. 2015 Jun;11(6):4053-62. doi: 10.3892/mmr.2015.3256. Epub 2015 Jan 26.
507 The hepatitis C virus (HCV) protein, p7, suppresses inflammatory responses to tumor necrosis factor (TNF)- via signal transducer and activator of transcription (STAT)3 and extracellular signal-regulated kinase (ERK)-mediated induction of suppressor of cytokine signaling (SOCS)3.FASEB J. 2019 Aug;33(8):8732-8744. doi: 10.1096/fj.201800629RR. Epub 2019 Jun 4.
508 Low oxygen tension enhances hepatitis C virus replication.J Virol. 2013 Mar;87(5):2935-48. doi: 10.1128/JVI.02534-12. Epub 2012 Dec 26.
509 Towards a better resolution of hepatitis C virus variants: CLIP sequencing of an HCV core fragment and automated assignment of genotypes and subtypes.J Virol Methods. 2008 Mar;148(1-2):25-33. doi: 10.1016/j.jviromet.2007.10.012. Epub 2007 Nov 28.
510 The liver-enriched transcription factor CREB-H is a growth suppressor protein underexpressed in hepatocellular carcinoma.Nucleic Acids Res. 2005 Mar 30;33(6):1859-73. doi: 10.1093/nar/gki332. Print 2005.
511 Model-based cost-effectiveness estimates of testing strategies for diagnosing hepatitis C virus infection in people who use injecting drugs in Senegal.Int J Drug Policy. 2020 Jan;75:102613. doi: 10.1016/j.drugpo.2019.102613. Epub 2019 Nov 28.
512 Multiple viral/self immunological cross-reactivity in liver kidney microsomal antibody positive hepatitis C virus infected patients is associated with the possession of HLA B51.Int J Immunopathol Pharmacol. 2004 Jan-Apr;17(1):83-92. doi: 10.1177/039463200401700112.
513 DCAF1 is involved in HCV replication through regulation of miR-122.Arch Virol. 2018 Apr;163(4):977-985. doi: 10.1007/s00705-017-3691-8. Epub 2018 Jan 11.
514 Serodiagnosis of hepatitis C virus (HCV) infection with an HCV core protein molecularly expressed by a recombinant baculovirus.Proc Natl Acad Sci U S A. 1991 Jun 1;88(11):4641-5. doi: 10.1073/pnas.88.11.4641.
515 Cellular DEAD-box RNA helicase DDX6 modulates interaction of miR-122 with the 5' untranslated region of hepatitis C virus RNA.Virology. 2017 Jul;507:231-241. doi: 10.1016/j.virol.2017.04.014. Epub 2017 Apr 26.
516 Laboratory of genetics and physiology 2 (LGP2) plays an essential role in hepatitis C virus infection-induced interferon responses.Hepatology. 2017 May;65(5):1478-1491. doi: 10.1002/hep.29050. Epub 2017 Mar 30.
517 Identification of Potential Gene Network Associated with HCV-Related Hepatocellular Carcinoma Using Microarray Analysis.Pathol Oncol Res. 2018 Jul;24(3):507-514. doi: 10.1007/s12253-017-0273-8. Epub 2017 Jul 1.
518 The Initiation Factors eIF2, eIF2A, eIF2D, eIF4A, and eIF4G Are Not Involved in Translation Driven by Hepatitis C Virus IRES in Human Cells.Front Microbiol. 2018 Feb 13;9:207. doi: 10.3389/fmicb.2018.00207. eCollection 2018.
519 Four translation initiation pathways employed by the leaderless mRNA in eukaryotes.Sci Rep. 2016 Nov 28;6:37905. doi: 10.1038/srep37905.
520 Glecaprevir/Pibrentasvir: First Global Approval.Drugs. 2017 Oct;77(16):1797-1804. doi: 10.1007/s40265-017-0817-y.
521 Age-specific prevalence, transmission and phylogeny of TT virus in the Czech Republic.BMC Infect Dis. 2004 Dec 3;4(1):56. doi: 10.1186/1471-2334-4-56.
522 Single nucleotide polymorphisms of toll-like receptor 7 in hepatitis C virus infection patients from a high-risk chinese population.Inflammation. 2015 Feb;38(1):142-51. doi: 10.1007/s10753-014-0016-x.
523 A single nucleotide polymorphism of the low molecular mass polypeptide 7 gene influences the interferon response in patients with chronic hepatitis C.J Viral Hepat. 2002 Sep;9(5):377-84. doi: 10.1046/j.1365-2893.2002.00365.x.
524 Forkhead box transcription factor regulation and lipid accumulation by hepatitis C virus.J Virol. 2014 Apr;88(8):4195-203. doi: 10.1128/JVI.03327-13. Epub 2014 Jan 29.
525 Vitamin D binding protein polymorphisms influence susceptibility to hepatitis C virus infection in a high-risk Chinese population.Gene. 2018 Dec 30;679:405-411. doi: 10.1016/j.gene.2018.09.021. Epub 2018 Sep 12.
526 Multi-Ancestry Genome-Wide Association Study of Spontaneous Clearance of Hepatitis C Virus.Gastroenterology. 2019 Apr;156(5):1496-1507.e7. doi: 10.1053/j.gastro.2018.12.014. Epub 2018 Dec 26.
527 Retinoid derivative Tp80 exhibits anti-hepatitis C virus activity through restoration of GI-GPx expression.J Med Virol. 2017 Jul;89(7):1224-1234. doi: 10.1002/jmv.24739. Epub 2017 Mar 28.
528 Zika Virus Persistently Infects and Is Basolaterally Released from Primary Human Brain Microvascular Endothelial Cells.mBio. 2017 Jul 11;8(4):e00952-17. doi: 10.1128/mBio.00952-17.
529 NS3 from Hepatitis C Virus Strain JFH-1 Is an Unusually Robust Helicase That Is Primed To Bind and Unwind Viral RNA.J Virol. 2017 Dec 14;92(1):e01253-17. doi: 10.1128/JVI.01253-17. Print 2018 Jan 1.
530 Relationship of serum haemojuvelin and hepcidin levels with iron level and erythropoietin requirement in prevalent hepatitis C virus positive haemodialysis patients.Nephrology (Carlton). 2018 Apr;23(4):323-330. doi: 10.1111/nep.13010.
531 Association of polymorphisms in HLA antigen presentation-related genes with the outcomes of HCV infection.PLoS One. 2015 Apr 13;10(4):e0123513. doi: 10.1371/journal.pone.0123513. eCollection 2015.
532 Hepatitis C virus core impacts expression of miR122 and miR204 involved in carcinogenic progression via regulation of TGFBRAP1 and HOTTIP expression.Onco Targets Ther. 2018 Mar 2;11:1173-1182. doi: 10.2147/OTT.S149254. eCollection 2018.
533 Effect of retreatment with interferon alone or interferon plus ribavirin on hepatitis C virus quasispecies diversification in nonresponder patients with chronic hepatitis C.J Virol. 1999 Sep;73(9):7241-7. doi: 10.1128/JVI.73.9.7241-7247.1999.
534 hnRNP L and NF90 interact with hepatitis C virus 5'-terminal untranslated RNA and promote efficient replication.J Virol. 2014 Jul;88(13):7199-209. doi: 10.1128/JVI.00225-14. Epub 2014 Apr 9.
535 Evaluation of hepatitis C virus as a risk factor for HIV-associated neuroretinal disorder.Clin Infect Dis. 2013 Dec;57(11):1618-25. doi: 10.1093/cid/cit550. Epub 2013 Sep 30.
536 NF90-NF45 is a selective RNA chaperone that rearranges viral and cellular riboswitches: biochemical analysis of a virus host factor activity.Nucleic Acids Res. 2017 Dec 1;45(21):12441-12454. doi: 10.1093/nar/gkx931.
537 Modulation of HCV replication and translation by ErbB3 binding protein1 isoforms.Virology. 2017 Jan;500:35-49. doi: 10.1016/j.virol.2016.10.006. Epub 2016 Oct 19.
538 Hepatitis C virus core protein potentiates proangiogenic activity of hepatocellular carcinoma cells.Oncotarget. 2017 Sep 30;8(49):86681-86692. doi: 10.18632/oncotarget.21407. eCollection 2017 Oct 17.
539 Predicting sustained viral response to hepatitis C using a rapid and simple IL28B rs8099917 genotyping assay.Antiviral Res. 2012 Apr;94(1):54-6. doi: 10.1016/j.antiviral.2012.02.007. Epub 2012 Feb 22.
540 Enhanced hepatocarcinogenesis in mouse models and human hepatocellular carcinoma by coordinate KLF6 depletion and increased messenger RNA splicing.Hepatology. 2012 Oct;56(4):1361-70. doi: 10.1002/hep.25810. Epub 2012 Aug 27.
541 Association Between Impaired V7.2+CD161++CD8+ (MAIT) and V7.2+CD161-CD8+ T-Cell Populations and Gut Dysbiosis in Chronically HIV- and/or HCV-Infected Patients.Front Microbiol. 2019 Aug 28;10:1972. doi: 10.3389/fmicb.2019.01972. eCollection 2019.
542 Portal, but not lobular, macrophages express matrix metalloproteinase-9: association with the ductular reaction and fibrosis in chronic hepatitis C.Liver Int. 2013 Apr;33(4):569-79. doi: 10.1111/liv.12050. Epub 2012 Dec 13.
543 Hepatic compartmentalization of exhausted and regulatory cells in HIV/HCV-coinfected patients.J Viral Hepat. 2015 Mar;22(3):281-8. doi: 10.1111/jvh.12291. Epub 2014 Sep 1.
544 Insufficiency of DNA repair enzyme ATM promotes naive CD4 T-cell loss in chronic hepatitis C virus infection.Cell Discov. 2018 Apr 10;4:16. doi: 10.1038/s41421-018-0015-4. eCollection 2018.
545 Estimated impact of hepatitis C-positive lung donor utilization on US donor lung supply.Am J Transplant. 2020 Jan;20(1):289-297. doi: 10.1111/ajt.15558. Epub 2019 Sep 5.
546 S-adenosyl-L-methionine modifies antioxidant-enzymes, glutathione-biosynthesis and methionine adenosyltransferases-1/2 in hepatitis C virus-expressing cells.World J Gastroenterol. 2016 Apr 14;22(14):3746-57. doi: 10.3748/wjg.v22.i14.3746.
547 Molecular dynamics and docking reveal the potency of novel GTP derivatives against RNA dependent RNA polymerase of genotype 4a HCV.Life Sci. 2019 Dec 1;238:116958. doi: 10.1016/j.lfs.2019.116958. Epub 2019 Oct 16.
548 Influence of IL28B and MxA gene polymorphisms on HCV clearance in Han Chinese population.Epidemiol Infect. 2018 Feb;146(3):379-385. doi: 10.1017/S0950268817002928. Epub 2017 Dec 22.
549 TLR4 Signaling via NANOG Cooperates With STAT3 to Activate Twist1 and Promote Formation of Tumor-Initiating Stem-Like Cells in Livers of Mice.Gastroenterology. 2016 Mar;150(3):707-19. doi: 10.1053/j.gastro.2015.11.002. Epub 2015 Nov 12.
550 NKp30 isoforms in patients with chronic hepatitis C virus infection.Immunology. 2015 Oct;146(2):234-42. doi: 10.1111/imm.12495. Epub 2015 Jul 8.
551 Polymorphisms of base-excision repair genes and the hepatocarcinogenesis.Gene. 2018 Oct 30;675:62-68. doi: 10.1016/j.gene.2018.06.056. Epub 2018 Jun 20.
552 Hepatitis C test uptake among historic blood transfusion recipients following media coverage of the Penrose Inquiry and an awareness-raising campaign.J Viral Hepat. 2019 Jan;26(1):93-100. doi: 10.1111/jvh.13016. Epub 2018 Nov 14.
553 Hepatitis C Virus Replication Depends on Endosomal Cholesterol Homeostasis.J Virol. 2017 Dec 14;92(1):e01196-17. doi: 10.1128/JVI.01196-17. Print 2018 Jan 1.
554 Efficacy and safety of sofosbuvir-based antiviral therapy to treat hepatitis C virus infection after kidney transplantation.Clin Kidney J. 2018 Jun;11(3):429-433. doi: 10.1093/ckj/sfx112. Epub 2017 Oct 30.
555 Isolation of specific and high-affinity RNA aptamers against NS3 helicase domain of hepatitis C virus.RNA. 2004 Aug;10(8):1277-90. doi: 10.1261/rna.7100904. Epub 2004 Jul 9.
556 2',5'-Oligoadenylate synthetase-like gene highly induced by hepatitis C virus infection in human liver is inhibitory to viral replication in vitro.Biochem Biophys Res Commun. 2010 Feb 12;392(3):397-402. doi: 10.1016/j.bbrc.2010.01.034. Epub 2010 Jan 13.
557 Trends in utilization of deceased donor kidneys based on hepatitis C virus status and impact of public health service labeling on discard.Transpl Infect Dis. 2020 Feb;22(1):e13204. doi: 10.1111/tid.13204. Epub 2019 Nov 26.
558 Clinical detection of Hepatitis C viral infection by yeast-secreted HCV-core:Gold-binding-peptide.Biosens Bioelectron. 2018 Nov 15;119:230-236. doi: 10.1016/j.bios.2018.07.026. Epub 2018 Aug 22.
559 Novel human SR-BI antibodies prevent infection and dissemination of HCV in vitro and in humanized mice.J Hepatol. 2012 Jul;57(1):17-23. doi: 10.1016/j.jhep.2012.02.018. Epub 2012 Mar 10.
560 Autophagy protects cells from HCV-induced defects in lipid metabolism.Gastroenterology. 2012 Mar;142(3):644-653.e3. doi: 10.1053/j.gastro.2011.11.033. Epub 2011 Dec 7.
561 Selective inhibitor of Wnt/-catenin/CBP signaling ameliorates hepatitis C virus-induced liver fibrosis in mouse model.Sci Rep. 2017 Mar 23;7(1):325. doi: 10.1038/s41598-017-00282-w.
562 High risk injecting behaviour among people who inject pharmaceutical opioids in Australia.Int J Drug Policy. 2017 Apr;42:1-6. doi: 10.1016/j.drugpo.2016.12.004. Epub 2017 Jan 16.
563 Design, synthesis, and structure-activity relationships of novel imidazo[4,5-c]pyridine derivatives as potent non-nucleoside inhibitors of hepatitis C virus NS5B.Bioorg Med Chem. 2018 May 15;26(9):2621-2631. doi: 10.1016/j.bmc.2018.04.029. Epub 2018 Apr 16.
564 Progress in the elimination of hepatitis C virus infection: A population-based cohort study in Spain.PLoS One. 2018 Dec 4;13(12):e0208554. doi: 10.1371/journal.pone.0208554. eCollection 2018.
565 Testosterone in Men With Chronic Hepatitis C Infection and After Hepatitis C Viral Clearance.Clin Infect Dis. 2019 Aug 1;69(4):571-576. doi: 10.1093/cid/ciy965.
566 Genetic variants of STAT-4 affect the development of graft fibrosis after liver transplantation for HCV-induced liver disease.Transplantation. 2013 Jan 15;95(1):203-8. doi: 10.1097/TP.0b013e318277e2f6.
567 SUMO1 depletion prevents lipid droplet accumulation and HCV replication.Arch Virol. 2016 Jan;161(1):141-8. doi: 10.1007/s00705-015-2628-3. Epub 2015 Oct 8.
568 Differential expression of intestinal trefoil factor in biliary epithelial cells of primary biliary cirrhosis.Hepatology. 2002 Nov;36(5):1227-35. doi: 10.1053/jhep.2002.36157.
569 The tight junction-associated protein occludin is required for a postbinding step in hepatitis C virus entry and infection.J Virol. 2009 Aug;83(16):8012-20. doi: 10.1128/JVI.00038-09. Epub 2009 Jun 10.
570 miR-215 Enhances HCV Replication by Targeting TRIM22 and Inactivating NF-B Signaling.Yonsei Med J. 2018 Jun;59(4):511-518. doi: 10.3349/ymj.2018.59.4.511.
571 Impact of All-Oral Direct-Acting Antivirals on Clinical and Economic Outcomes in Patients With Chronic Hepatitis C in the United States.Hepatology. 2019 Mar;69(3):1032-1045. doi: 10.1002/hep.30303. Epub 2019 Feb 10.
572 HCV adaptation to HIV coinfection.Infect Genet Evol. 2018 Nov;65:216-225. doi: 10.1016/j.meegid.2018.07.039. Epub 2018 Jul 31.
573 Nardilysin promotes hepatocellular carcinoma through activation of signal transducer and activator of transcription 3.Cancer Sci. 2017 May;108(5):910-917. doi: 10.1111/cas.13204. Epub 2017 Apr 24.
574 High prevalence of HFE gene mutations in patients with porphyria cutanea tarda in the Czech Republic.Br J Dermatol. 2008 Sep;159(3):585-90. doi: 10.1111/j.1365-2133.2008.08693.x. Epub 2008 Jun 28.
575 Distinct Roles for Intracellular and Extracellular Lipids in Hepatitis C Virus Infection.PLoS One. 2016 Jun 9;11(6):e0156996. doi: 10.1371/journal.pone.0156996. eCollection 2016.
576 Multicenter evaluation of the performance characteristics of the bayer VERSANT HCV RNA 3.0 assay (bDNA).J Clin Microbiol. 2004 Feb;42(2):563-9. doi: 10.1128/JCM.42.2.563-569.2004.
577 Long chain acyl-CoA synthetase 3-mediated phosphatidylcholine synthesis is required for assembly of very low density lipoproteins in human hepatoma Huh7 cells.J Biol Chem. 2008 Jan 11;283(2):849-54. doi: 10.1074/jbc.M706160200. Epub 2007 Nov 14.
578 Assessment of the Prevalence of Non-Organ-Specific Autoantibodies in Egyptian Patients with HCV.Immunol Invest. 2020 Aug;49(6):676-686. doi: 10.1080/08820139.2019.1699108. Epub 2019 Dec 10.
579 Hepatitis C virus infection in mouse hepatoma cells co-expressing human CD81 and Sip-L.Biochem Biophys Res Commun. 2008 Jul 18;372(1):157-61. doi: 10.1016/j.bbrc.2008.05.018. Epub 2008 May 12.
580 Occult hepatitis C virus infection in patients in whom the etiology of persistently abnormal results of liver-function tests is unknown.J Infect Dis. 2004 Jan 1;189(1):7-14. doi: 10.1086/380202. Epub 2003 Dec 31.
581 Relevance of Rab Proteins for the Life Cycle of Hepatitis C Virus.Front Cell Dev Biol. 2018 Dec 4;6:166. doi: 10.3389/fcell.2018.00166. eCollection 2018.
582 Identification of hepatitis C virus genotypes among hospitalized patients in British Columbia, Canada.J Infect Dis. 1995 Apr;171(4):1034-8. doi: 10.1093/infdis/171.4.1034.
583 MicroRNA-122 dependent binding of Ago2 protein to hepatitis C virus RNA is associated with enhanced RNA stability and translation stimulation.PLoS One. 2013;8(2):e56272. doi: 10.1371/journal.pone.0056272. Epub 2013 Feb 6.
584 miR-122 and Ago interactions with the HCV genome alter the structure of the viral 5' terminus.Nucleic Acids Res. 2019 Jun 4;47(10):5307-5324. doi: 10.1093/nar/gkz194.
585 Advanced Hepatitis C Virus Replication PDE Models within a Realistic Intracellular Geometric Environment.Int J Environ Res Public Health. 2019 Feb 12;16(3):513. doi: 10.3390/ijerph16030513.
586 Single- and multiple-ascending-dose studies of the NS3 protease inhibitor asunaprevir in subjects with or without chronic hepatitis C.Antimicrob Agents Chemother. 2012 Apr;56(4):1838-44. doi: 10.1128/AAC.05854-11. Epub 2012 Jan 30.
587 AP1S3 is required for hepatitis C virus infection by stabilizing E2 protein.Antiviral Res. 2016 Jul;131:26-34. doi: 10.1016/j.antiviral.2016.04.006. Epub 2016 Apr 11.
588 The AP2M1 gene expression is a promising biomarker for predicting survival of patients with hepatocellular carcinoma.J Cell Biochem. 2019 Mar;120(3):4140-4146. doi: 10.1002/jcb.27699. Epub 2018 Sep 27.
589 Modular cell-based platform for high throughput identification of compounds that inhibit a viral interferon antagonist of choice.Antiviral Res. 2018 Feb;150:79-92. doi: 10.1016/j.antiviral.2017.10.012. Epub 2017 Oct 14.
590 Characterization of apolipoprotein C1 in hepatitis C virus infection and morphogenesis.Virology. 2018 Nov;524:1-9. doi: 10.1016/j.virol.2018.08.004. Epub 2018 Aug 18.
591 Expression of apolipoprotein C-IV is regulated by Ku antigen/peroxisome proliferator-activated receptor gamma complex and correlates with liver steatosis.J Hepatol. 2008 Nov;49(5):787-98. doi: 10.1016/j.jhep.2008.06.029. Epub 2008 Sep 7.
592 Antiviral activity of boceprevir monotherapy in treatment-naive subjects with chronic hepatitis C genotype 2/3.J Hepatol. 2013 Jul;59(1):31-7. doi: 10.1016/j.jhep.2013.02.018. Epub 2013 Feb 27.
593 TIM-1 Promotes Hepatitis C Virus Cell Attachment and Infection.J Virol. 2017 Jan 3;91(2):e01583-16. doi: 10.1128/JVI.01583-16. Print 2017 Jan 15.
594 Identification of TAF1, SAT1, and ARHGEF9 as DNA methylation biomarkers for hepatocellular carcinoma.J Cell Physiol. 2020 Jan;235(1):611-618. doi: 10.1002/jcp.28999. Epub 2019 Jul 8.
595 Recurrent inactivating mutations of ARID2 in non-small cell lung carcinoma.Int J Cancer. 2013 May 1;132(9):2217-21. doi: 10.1002/ijc.27900. Epub 2012 Nov 20.
596 Genetic Markers of the Host in Persons Living with HTLV-1, HIV and HCV Infections.Viruses. 2016 Feb 3;8(2):38. doi: 10.3390/v8020038.
597 Induction of selective autophagy in cells replicating hepatitis C virus genome.J Gen Virol. 2018 Dec;99(12):1643-1657. doi: 10.1099/jgv.0.001161. Epub 2018 Oct 12.
598 Immunization against hepatitis C virus with a fusion protein containing the extra domain A from fibronectin and the hepatitis C virus NS3 protein.J Hepatol. 2009 Sep;51(3):520-7. doi: 10.1016/j.jhep.2009.06.005. Epub 2009 Jun 23.
599 A polymorphism that delays fibrosis in hepatitis C promotes alternative splicing of AZIN1, reducing fibrogenesis.Hepatology. 2011 Dec;54(6):2198-207. doi: 10.1002/hep.24608.
600 A polymorphism linked to RRAS, SCAF1, IRF3 and BCL2L12 genes is associated with cirrhosis in hepatitis C virus carriers.Liver Int. 2014 Apr;34(4):558-66. doi: 10.1111/liv.12330. Epub 2013 Oct 16.
601 Synthetic Antibody Binding to a Preorganized RNA Domain of Hepatitis C Virus Internal Ribosome Entry Site Inhibits Translation.ACS Chem Biol. 2020 Jan 17;15(1):205-216. doi: 10.1021/acschembio.9b00785. Epub 2019 Dec 10.
602 Influence of sustained viral response on the regression of fibrosis and portal hypertension in cirrhotic HCV patients treated with antiviral triple therapy.Rev Esp Enferm Dig. 2017 Jan;109(1):17-25. doi: 10.17235/reed.2016.4235/2016.
603 High prevalence of a variety of autoantibodies in a population of hepatitis C virus-infected individuals.APMIS. 2018 Jun;126(6):515-522. doi: 10.1111/apm.12850.
604 Fine-mapping butyrophilin family genes revealed several polymorphisms influencing viral genotype selection in hepatitis C infection.Genes Immun. 2015 Jul-Aug;16(5):297-300. doi: 10.1038/gene.2015.14. Epub 2015 Apr 30.
605 Inflammasome Genes' Polymorphisms in Egyptian Chronic Hepatitis C Patients: Influence on Vulnerability to Infection and Response to Treatment.Mediators Inflamm. 2019 Jan 9;2019:3273645. doi: 10.1155/2019/3273645. eCollection 2019.
606 Increases in endothelial caveolin-1 and cavins correlate with cirrhosis progression.Micron. 2015 Sep;76:52-61. doi: 10.1016/j.micron.2015.03.009. Epub 2015 Mar 31.
607 Lower copy numbers of the chemokine CCL3L1 gene in patients with chronic hepatitis C.J Hepatol. 2010 Feb;52(2):153-9. doi: 10.1016/j.jhep.2009.11.001. Epub 2009 Nov 27.
608 Myeloid dendritic cells of patients with chronic HCV infection induce proliferation of regulatory T lymphocytes.Gastroenterology. 2008 Dec;135(6):2119-27. doi: 10.1053/j.gastro.2008.07.082. Epub 2008 Aug 7.
609 Hepatic CD1d expression in hepatitis C virus infection and recognition by resident proinflammatory CD1d-reactive T cells.J Immunol. 2004 Aug 1;173(3):2159-66. doi: 10.4049/jimmunol.173.3.2159.
610 DNAM-1 Activating Receptor and Its Ligands: How Do Viruses Affect the NK Cell-Mediated Immune Surveillance during the Various Phases of Infection?.Int J Mol Sci. 2019 Jul 30;20(15):3715. doi: 10.3390/ijms20153715.
611 Discovery of cellular proteins required for the early steps of HCV infection using integrative genomics.PLoS One. 2013 Apr 12;8(4):e60333. doi: 10.1371/journal.pone.0060333. Print 2013.
612 CS-SELEX generates high-affinity ssDNA aptamers as molecular probes for hepatitis C virus envelope glycoprotein E2.PLoS One. 2009 Dec 3;4(12):e8142. doi: 10.1371/journal.pone.0008142.
613 The identification of three sizes of core proteins during the establishment of persistent hepatitis C virus infection in vitro.Virol Sin. 2013 Jun;28(3):129-35. doi: 10.1007/s12250-013-3296-7. Epub 2013 Mar 25.
614 Hepatitis C Virus core+1/ARF Protein Modulates the Cyclin D1/pRb Pathway and Promotes Carcinogenesis.J Virol. 2018 Apr 13;92(9):e02036-17. doi: 10.1128/JVI.02036-17. Print 2018 May 1.
615 Neutralizing antibodies in patients with chronic hepatitis C, genotype 1, against a panel of genotype 1 culture viruses: lack of correlation to treatment outcome.PLoS One. 2013 May 7;8(5):e62674. doi: 10.1371/journal.pone.0062674. Print 2013.
616 YKL-40-gene polymorphism affects acute cellular rejection and fibrosis progression after transplantation for hepatitis C virus-induced liver disease.J Gastroenterol Hepatol. 2013 Jan;28(1):153-60. doi: 10.1111/j.1440-1746.2012.07270.x.
617 Hepatitis C virus NS5B protein delays s phase progression in human hepatocyte-derived cells by relocalizing cyclin-dependent kinase 2-interacting protein (CINP).J Biol Chem. 2011 Jul 29;286(30):26603-15. doi: 10.1074/jbc.M111.225672. Epub 2011 May 31.
618 Altered m(6)A Modification of Specific Cellular Transcripts Affects Flaviviridae Infection.Mol Cell. 2020 Feb 6;77(3):542-555.e8. doi: 10.1016/j.molcel.2019.11.007. Epub 2019 Dec 3.
619 RNA triphosphatase DUSP11 enables exonuclease XRN-mediated restriction of hepatitis C virus.Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8197-8202. doi: 10.1073/pnas.1802326115. Epub 2018 Jul 23.
620 In vivo combination of human anti-envelope glycoprotein E2 and -Claudin-1 monoclonal antibodies for prevention of hepatitis C virus infection.Antiviral Res. 2019 Feb;162:136-141. doi: 10.1016/j.antiviral.2018.12.018. Epub 2018 Dec 30.
621 CLEC4M-positive and CD81-negative Huh7 cells are not susceptible to JFH-1 HCVcc infection but mediate transinfection.Arch Virol. 2014 Nov;159(11):2949-55. doi: 10.1007/s00705-014-2150-z. Epub 2014 Jun 26.
622 Screening HCV genotype-specific epitope peptides based on conserved sequence analysis and B cell epitope prediction in HCV E2 region.Immunol Res. 2018 Feb;66(1):67-73. doi: 10.1007/s12026-017-8962-7.
623 Metabolic alterations and hepatitis C: From bench to bedside.World J Gastroenterol. 2016 Jan 28;22(4):1461-76. doi: 10.3748/wjg.v22.i4.1461.
624 Eukaryotic translation initiation factor 4AII contributes to microRNA-122 regulation of hepatitis C virus replication.Nucleic Acids Res. 2018 Jul 6;46(12):6330-6343. doi: 10.1093/nar/gky262.
625 Selective transmission of hepatitis C virus genotypes and quasispecies in humans and experimentally infected chimpanzees.J Gen Virol. 2006 Jan;87(Pt 1):83-91. doi: 10.1099/vir.0.81268-0.
626 Proteasome activator and antigen-processing aminopeptidases are regulated by virus-induced type I interferon in the hepatitis C virus-infected liver.J Interferon Cytokine Res. 2007 Dec;27(12):985-90. doi: 10.1089/jir.2007.0039.
627 Regulation of Hepatitis C Virus Infection by Cellular Retinoic Acid Binding Proteins through the Modulation of Lipid Droplet Abundance.J Virol. 2019 Apr 3;93(8):e02302-18. doi: 10.1128/JVI.02302-18. Print 2019 Apr 15.
628 Critical role of CREBH-mediated induction of transforming growth factor 2 by hepatitis C virus infection in fibrogenic responses in hepatic stellate cells.Hepatology. 2017 Nov;66(5):1430-1443. doi: 10.1002/hep.29319. Epub 2017 Sep 29.
629 Cysteine-rich secretory protein 3 inhibits hepatitis C virus at the initial phase of infection.Biochem Biophys Res Commun. 2014 Jul 25;450(2):1076-82. doi: 10.1016/j.bbrc.2014.06.106. Epub 2014 Jun 27.
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631 Standardized hepatitis C virus RNA panels for nucleic acid testing assays.J Clin Virol. 2001 Jan;20(1-2):35-40. doi: 10.1016/s1386-6532(00)00153-0.
632 Association of a variant in the regulatory region of NADPH oxidase 4 gene and metabolic syndrome in patients with chronic hepatitis C.Eur J Med Res. 2015 Mar 28;20(1):45. doi: 10.1186/s40001-015-0136-2.
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634 A screen for novel hepatitis C virus RdRp inhibitor identifies a broad-spectrum antiviral compound.Sci Rep. 2017 Jul 19;7(1):5816. doi: 10.1038/s41598-017-04449-3.
635 Hepatitis C virus infection in Irish drug users and prisoners - a scoping review.BMC Infect Dis. 2019 Aug 8;19(1):702. doi: 10.1186/s12879-019-4218-6.
636 Induction of cell-mediated immune responses in mice by DNA vaccines that express hepatitis C virus NS3 mutants lacking serine protease and NTPase/RNA helicase activities.PLoS One. 2014 Jun 5;9(6):e98877. doi: 10.1371/journal.pone.0098877. eCollection 2014.
637 RNA helicase DDX3 maintains lipid homeostasis through upregulation of the microsomal triglyceride transfer protein by interacting with HNF4 and SHP.Sci Rep. 2017 Jan 27;7:41452. doi: 10.1038/srep41452.
638 Endoscopic Therapy is Effective for Recurrent Anastomotic Biliary Strictures after Orthotopic Liver Transplantation.Ann Hepatol. 2017 November-December,;16(6):924-931. doi: 10.5604/01.3001.0010.5284.
639 Correlation between the DEPDC5 rs1012068 polymorphism and the risk of HBV-related hepatocellular carcinoma.Clin Res Hepatol Gastroenterol. 2019 Aug;43(4):446-450. doi: 10.1016/j.clinre.2018.12.005. Epub 2019 Jan 23.
640 Rates and impact of hepatitis on human immunodeficiency virus infection in a large African cohort.World J Gastroenterol. 2013 Mar 14;19(10):1602-10. doi: 10.3748/wjg.v19.i10.1602.
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642 Dysregulation of the cohesin subunit RAD21 by Hepatitis C virus mediates host-virus interactions.Nucleic Acids Res. 2019 Mar 18;47(5):2455-2471. doi: 10.1093/nar/gkz052.
643 Role of the endoplasmic reticulum-associated degradation (ERAD) pathway in degradation of hepatitis C virus envelope proteins and production of virus particles.J Biol Chem. 2011 Oct 28;286(43):37264-73. doi: 10.1074/jbc.M111.259085. Epub 2011 Aug 30.
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648 Overlapping but distinct specificities of anti-liver-kidney microsome antibodies in autoimmune hepatitis type II and hepatitis C revealed by recombinant native CYP2D6 and novel peptide epitopes.Clin Exp Immunol. 1999 Nov;118(2):290-7. doi: 10.1046/j.1365-2249.1999.01027.x.
649 Hepatitis C virus NS3 protein interacts with ELKS-{delta} and ELKS-{alpha}, members of a novel protein family involved in intracellular transport and secretory pathways.J Gen Virol. 2005 Aug;86(Pt 8):2197-2208. doi: 10.1099/vir.0.80862-0.
650 The Host Factor Erlin-1 is Required for Efficient Hepatitis C Virus Infection.Cells. 2019 Dec 2;8(12):1555. doi: 10.3390/cells8121555.
651 Syntenin regulates hepatitis C virus sensitivity to neutralizing antibody by promoting E2 secretion through exosomes.J Hepatol. 2019 Jul;71(1):52-61. doi: 10.1016/j.jhep.2019.03.006. Epub 2019 Mar 15.
652 HIV infection and hepatitis C virus genotype 1a are associated with phylogenetic clustering among people with recently acquired hepatitis C virus infection.Infect Genet Evol. 2016 Jan;37:252-8. doi: 10.1016/j.meegid.2015.11.028. Epub 2015 Nov 26.
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655 Elevated serum activity of MBL and ficolin-2 as biomarkers for progression to hepatocellular carcinoma in chronic HCV infection.Virology. 2019 Apr;530:99-106. doi: 10.1016/j.virol.2019.02.002. Epub 2019 Feb 12.
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657 Prevalence of hepatitis C virus infection in patients with COPD.Epidemiol Infect. 2010 Feb;138(2):167-73. doi: 10.1017/S0950268809990276. Epub 2009 Jun 29.
658 A single-amino-acid mutation in hepatitis C virus NS5A disrupts physical and functional interaction with the transcription factor HNF-1.J Gen Virol. 2015 Aug;96(8):2200-2205. doi: 10.1099/vir.0.000179. Epub 2015 May 8.
659 HCBP6 Is Involved in the Development of Hepatic Steatosis Induced by High-Fat Diet and CCL4 in Rats.Ann Hepatol. 2018 May-June;17(3):511-518. doi: 10.5604/01.3001.0011.7396. Epub 2018 Apr 9.
660 HIV and HCV Co-Culture Promotes Profibrogenic Gene Expression through an Epimorphin-Mediated ERK Signaling Pathway in Hepatic Stellate Cells.PLoS One. 2016 Jun 30;11(6):e0158386. doi: 10.1371/journal.pone.0158386. eCollection 2016.
661 Hepatitis C Virus-Induced FUT8 Causes 5-FU Drug Resistance in Human Hepatoma Huh7.5.1 Cells.Viruses. 2019 Apr 24;11(4):378. doi: 10.3390/v11040378.
662 Downregulation of autophagy-related gene ATG5 and GABARAP expression by IFN-1 contributes to its anti-HCV activity in human hepatoma cells.Antiviral Res. 2017 Apr;140:83-94. doi: 10.1016/j.antiviral.2017.01.016. Epub 2017 Jan 26.
663 Predictive potential of IL-18 -607 and osteopontin -442 polymorphism in interferon-based therapy of HCV infection in the Pakistani population.Viral Immunol. 2014 Oct;27(8):404-11. doi: 10.1089/vim.2014.0044. Epub 2014 Sep 8.
664 Functional and Physical Interaction between the Arf Activator GBF1 and Hepatitis C Virus NS3 Protein.J Virol. 2019 Mar 5;93(6):e01459-18. doi: 10.1128/JVI.01459-18. Print 2019 Mar 15.
665 Myxovirus resistance protein A inhibits hepatitis C virus replication through JAK-STAT pathway activation.Arch Virol. 2018 Jun;163(6):1429-1438. doi: 10.1007/s00705-018-3748-3. Epub 2018 Feb 7.
666 Nrf2 activates augmenter of liver regeneration (ALR) via antioxidant response element and links oxidative stress to liver regeneration.Mol Med. 2013 Aug 28;19(1):237-44. doi: 10.2119/molmed.2013.00027.
667 Large-scale search of single nucleotide polymorphisms for hepatocellular carcinoma susceptibility genes in patients with hepatitis C.Hepatology. 2005 Oct;42(4):846-53. doi: 10.1002/hep.20860.
668 Mevalonate pathway modulation is associated with hepatitis C virus RNA presence in peripheral blood mononuclear cells.Virus Res. 2009 Oct;145(1):141-4. doi: 10.1016/j.virusres.2009.06.001. Epub 2009 Jun 18.
669 Up-regulation of glycolipid transfer protein by bicyclol causes spontaneous restriction of hepatitis C virus replication.Acta Pharm Sin B. 2019 Jul;9(4):769-781. doi: 10.1016/j.apsb.2019.01.013. Epub 2019 Jan 29.
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671 Exploring the Diagnostic Potential of Serum Golgi Protein 73 for Hepatic Necroinflammation and Fibrosis in Chronic HCV Infection with Different Stages of Liver Injuries.Dis Markers. 2019 Sep 17;2019:3862024. doi: 10.1155/2019/3862024. eCollection 2019.
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673 A method for detecting hepatitis C envelope specific memory B cells from multiple genotypes using cocktail E2 tetramers.J Immunol Methods. 2019 Sep;472:65-74. doi: 10.1016/j.jim.2019.06.016. Epub 2019 Jun 19.
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676 The Marburg I variant (G534E) of the factor VII-activating protease determines liver fibrosis in hepatitis C infection by reduced proteolysis of platelet-derived growth factor BB.Hepatology. 2009 Mar;49(3):775-80. doi: 10.1002/hep.22707.
677 Utility of a one-step screening and diagnosis strategy for viremic HCV infection among people who inject drugs in Catalonia.Int J Drug Policy. 2019 Dec;74:236-245. doi: 10.1016/j.drugpo.2019.10.012. Epub 2019 Nov 6.
678 Expression of programmed cell death protein 1 and T-cell immunoglobulin- and mucin-domain-containing molecule-3 on peripheral blood CD4+CD8+ double positive T cells in patients with chronic hepatitis C virus infection and in subjects who spontaneously cleared the virus.J Viral Hepat. 2019 Aug;26(8):942-950. doi: 10.1111/jvh.13108. Epub 2019 Apr 29.
679 Gene expression patterns in livers of Hispanic patients infected with hepatitis C virus.Autoimmunity. 2011 Nov;44(7):532-42. doi: 10.3109/08916934.2011.592881. Epub 2011 Aug 24.
680 Polymorphisms in MICA, but not in DEPDC5, HCP5 or PNPLA3, are associated with chronic hepatitis C-related hepatocellular carcinoma.Sci Rep. 2017 Sep 19;7(1):11912. doi: 10.1038/s41598-017-10363-5.
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683 Genetic variants in human leukocyte antigen-DP influence both hepatitis C virus persistence and hepatitis C virus F protein generation in the Chinese Han population.Int J Mol Sci. 2014 Jun 3;15(6):9826-43. doi: 10.3390/ijms15069826.
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686 Relation of HLA class I and II supertypes with spontaneous clearance of hepatitis C virus.Genes Immun. 2013 Jul-Aug;14(5):330-5. doi: 10.1038/gene.2013.25. Epub 2013 May 2.
687 TRAIL receptor I (DR4) polymorphisms C626G and A683C are associated with an increased risk for hepatocellular carcinoma (HCC) in HCV-infected patients.BMC Cancer. 2012 Mar 8;12:85. doi: 10.1186/1471-2407-12-85.
688 Human Leukocyte Antigen (HLA) and Immune Regulation: How Do Classical and Non-Classical HLA Alleles Modulate Immune Response to Human Immunodeficiency Virus and Hepatitis C Virus Infections?.Front Immunol. 2017 Jul 18;8:832. doi: 10.3389/fimmu.2017.00832. eCollection 2017.
689 Interactions Between KIR3DS1 and HLA-F Activate Natural Killer Cells to Control HCV Replication in Cell Culture.Gastroenterology. 2018 Nov;155(5):1366-1371.e3. doi: 10.1053/j.gastro.2018.07.019. Epub 2018 Jul 19.
690 The potential of signal peptide peptidase as a therapeutic target for hepatitis C.Expert Opin Ther Targets. 2017 Sep;21(9):827-836. doi: 10.1080/14728222.2017.1369959. Epub 2017 Aug 22.
691 RNA-binding protein hnRNP D modulates internal ribosome entry site-dependent translation of hepatitis C virus RNA.J Virol. 2008 Dec;82(24):12082-93. doi: 10.1128/JVI.01405-08. Epub 2008 Oct 8.
692 A human proteome microarray identifies that the heterogeneous nuclear ribonucleoprotein K (hnRNP K) recognizes the 5' terminal sequence of the hepatitis C virus RNA.Mol Cell Proteomics. 2014 Jan;13(1):84-92. doi: 10.1074/mcp.M113.031682. Epub 2013 Oct 10.
693 Diagnosis and monitoring of HCV infection using the cobas() HCV test for use on the cobas() 6800/8800 systems.J Clin Virol. 2018 May;102:63-69. doi: 10.1016/j.jcv.2018.02.017. Epub 2018 Feb 24.
694 The allele 4 of neck region liver-lymph node-specific ICAM-3-grabbing integrin variant is associated with spontaneous clearance of hepatitis C virus and decrease of viral loads.Clin Microbiol Infect. 2014 May;20(5):O325-32. doi: 10.1111/1469-0691.12403. Epub 2013 Nov 6.
695 T lymphocytes from chronic HCV-infected patients are primed for activation-induced apoptosis and express unique pro-apoptotic gene signature.PLoS One. 2013 Oct 10;8(10):e77008. doi: 10.1371/journal.pone.0077008. eCollection 2013.
696 Hepatitis C virus drives increased type I interferon-associated impairments associated with fibrosis severity in antiretroviral treatment-treated HIV-1-hepatitis C virus-coinfected individuals.AIDS. 2017 Jun 1;31(9):1223-1234. doi: 10.1097/QAD.0000000000001455.
697 A Long Noncoding RNA Regulates Hepatitis C Virus Infection Through Interferon Alpha-Inducible Protein 6.Hepatology. 2019 Mar;69(3):1004-1019. doi: 10.1002/hep.30266. Epub 2019 Feb 13.
698 Hepatic IFN-Induced Protein with Tetratricopeptide Repeats Regulation of HCV Infection.J Interferon Cytokine Res. 2019 Mar;39(3):133-146. doi: 10.1089/jir.2018.0103.
699 Hepatitis C virus infection modulates expression of interferon stimulatory gene IFITM1 by upregulating miR-130A.J Virol. 2012 Sep;86(18):10221-5. doi: 10.1128/JVI.00882-12. Epub 2012 Jul 11.
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711 History of Marijuana Use Does Not Affect Outcomes on the Liver Transplant Waitlist.Transplantation. 2018 May;102(5):794-802. doi: 10.1097/TP.0000000000002045.
712 A frequent hypofunctional IRAK2 variant is associated with reduced spontaneous hepatitis C virus clearance.Hepatology. 2015 Nov;62(5):1375-87. doi: 10.1002/hep.28105. Epub 2015 Sep 28.
713 Depletion of MicroRNA-373 Represses the Replication of Hepatitis C Virus via Activation of Type 1 Interferon Response by Targeting IRF5.Yonsei Med J. 2018 Dec;59(10):1181-1189. doi: 10.3349/ymj.2018.59.10.1181.
714 Removal of the C6 Vaccinia Virus Interferon- Inhibitor in the Hepatitis C Vaccine Candidate MVA-HCV Elicited in Mice High Immunogenicity in Spite of Reduced Host Gene Expression.Viruses. 2018 Aug 8;10(8):414. doi: 10.3390/v10080414.
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723 Decreased interferon- production by NK cells from KIR haplotype B carriers in hepatitis C virus infection.Liver Int. 2019 Jul;39(7):1237-1245. doi: 10.1111/liv.14172. Epub 2019 Jun 26.
724 Decreased expression of an ATP-binding cassette transporter, MRP2, in human livers with hepatitis C virus infection.J Hepatol. 2001 Dec;35(6):765-73. doi: 10.1016/s0168-8278(01)00216-1.
725 Aberrant DNA methylation profile and frequent methylation of KLK10 and OXGR1 genes in hepatocellular carcinoma.Genes Chromosomes Cancer. 2009 Dec;48(12):1057-68. doi: 10.1002/gcc.20708.
726 Functional characterization of nuclear localization and export signals in hepatitis C virus proteins and their role in the membranous web.PLoS One. 2014 Dec 8;9(12):e114629. doi: 10.1371/journal.pone.0114629. eCollection 2014.
727 Activation-induced cytidine deaminase is dispensable for virus-mediated liver and skin tumor development in mouse models.Int Immunol. 2014 Jul;26(7):397-406. doi: 10.1093/intimm/dxu040. Epub 2014 Feb 25.
728 Serum cytokeratin-18 and its relation to liver fibrosis and steatosis diagnosed by FibroScan and controlled attenuation parameter in nonalcoholic fatty liver disease and hepatitis C virus patients.Eur J Gastroenterol Hepatol. 2019 May;31(5):633-641. doi: 10.1097/MEG.0000000000001385.
729 Genetic markers of lipid metabolism genes associated with low susceptibility to HCV infection.Sci Rep. 2019 Jun 21;9(1):9054. doi: 10.1038/s41598-019-45389-4.
730 Diagnostic Accuracy of Acoustic Radiation Force Impulse (ARFI) and Wisteria floribunda Agglutinin-Positive Mac-2-Binding Protein (WFA?M2BP) in Patients with Chronic Liver Disease.Med Sci Monit. 2019 Sep 24;25:7169-7174. doi: 10.12659/MSM.916533.
731 Hepatitis C virus nonstructural region 5A protein is a potent transcriptional activator.J Virol. 1997 Nov;71(11):8856-9. doi: 10.1128/JVI.71.11.8856-8859.1997.
732 CD14(+) monocyte-derived galectin-9 induces natural killer cell cytotoxicity in chronic hepatitis C.Hepatology. 2017 Jan;65(1):18-31. doi: 10.1002/hep.28847. Epub 2016 Nov 5.
733 Screening of hepatitis C virus genotypes in urticaria patients in Saudi Arabia.Genet Test Mol Biomarkers. 2012 Aug;16(8):964-7. doi: 10.1089/gtmb.2012.0014. Epub 2012 Jul 12.
734 Impact of soluble CD26 on treatment outcome and hepatitis C virus-specific T cells in chronic hepatitis C virus genotype 1 infection.PLoS One. 2013;8(2):e56991. doi: 10.1371/journal.pone.0056991. Epub 2013 Feb 20.
735 Lysophosphatidylcholine acyltransferase 1 is downregulated by hepatitis C virus: impact on production of lipo-viro-particles.Gut. 2017 Dec;66(12):2160-2169. doi: 10.1136/gutjnl-2016-311508. Epub 2016 Aug 31.
736 Genetic variations in humans associated with differences in the course of hepatitis C.Biochem Biophys Res Commun. 2004 Apr 30;317(2):335-41. doi: 10.1016/j.bbrc.2004.03.056.
737 Lumican, an extracellular matrix proteoglycan, is a novel requisite for hepatic fibrosis.Lab Invest. 2012 Dec;92(12):1712-25. doi: 10.1038/labinvest.2012.121. Epub 2012 Sep 24.
738 Induction of incomplete autophagic response by hepatitis C virus via the unfolded protein response.Hepatology. 2008 Oct;48(4):1054-61. doi: 10.1002/hep.22464.
739 Alcohol-induced autophagy via upregulation of PIASy promotes HCV replication in human hepatoma cells.Cell Death Dis. 2018 Sep 5;9(9):898. doi: 10.1038/s41419-018-0845-x.
740 Treatment of acute hepatitis C genotypes 1 and 4 with 8 weeks of grazoprevir plus elbasvir (DAHHS2): an open-label, multicentre, single-arm, phase 3b trial.Lancet Gastroenterol Hepatol. 2019 Apr;4(4):269-277. doi: 10.1016/S2468-1253(18)30414-X. Epub 2019 Jan 17.
741 Evaluation of Three Rapid Screening Tests for Detection of Hepatitis C Antibodies on Mass Scale.Crit Rev Eukaryot Gene Expr. 2019;29(1):25-28. doi: 10.1615/CritRevEukaryotGeneExpr.2018025062.
742 Identification of special key genes for alcohol-related hepatocellular carcinoma through bioinformatic analysis.PeerJ. 2019 Feb 6;7:e6375. doi: 10.7717/peerj.6375. eCollection 2019.
743 Dynamic Interaction of Stress Granules, DDX3X, and IKK- Mediates Multiple Functions in Hepatitis C Virus Infection.J Virol. 2015 May;89(10):5462-77. doi: 10.1128/JVI.03197-14. Epub 2015 Mar 4.
744 Oxidative Stress Attenuates Lipid Synthesis and Increases Mitochondrial Fatty Acid Oxidation in Hepatoma Cells Infected with Hepatitis C Virus.J Biol Chem. 2016 Jan 22;291(4):1974-1990. doi: 10.1074/jbc.M115.674861. Epub 2015 Dec 1.
745 Relationship between the rs2596542 polymorphism in the MICA gene promoter and HBV/HCV infection-induced hepatocellular carcinoma: a meta-analysis.BMC Med Genet. 2019 Aug 16;20(1):142. doi: 10.1186/s12881-019-0871-2.
746 Clinicopathological features of hepatitis C virus disease after living donor liver transplantation: relationship with in situ hybridisation data.Pathology. 2011 Feb;43(2):156-60. doi: 10.1097/PAT.0b013e32834317ed.
747 The structural HCV genes delivered by MPG cell penetrating peptide are directed to enhance immune responses in mice model.Drug Deliv. 2016 Oct;23(8):2852-2859. doi: 10.3109/10717544.2015.1108375. Epub 2015 Nov 11.
748 Sequence analysis of the immunoglobulin antigen receptor of hepatitis C virus-associated non-Hodgkin lymphomas suggests that the malignant cells are derived from the rheumatoid factor-producing cells that occur mainly in type II cryoglobulinemia.Blood. 2000 Nov 15;96(10):3578-84.
749 Aberrant promoter methylation profiles of tumor suppressor genes in hepatocellular carcinoma.Am J Pathol. 2003 Sep;163(3):1101-7. doi: 10.1016/S0002-9440(10)63469-4.
750 Expression Levels of the Uridine-Cytidine Kinase Like-1 Protein As a Novel Prognostic Factor for Hepatitis C Virus-Associated Hepatocellular Carcinomas.Acta Naturae. 2017 Jul-Sep;9(3):108-114.
751 Role of phosphatidylinositol 4-phosphate (PI4P) and its binding protein GOLPH3 in hepatitis C virus secretion.J Biol Chem. 2012 Aug 10;287(33):27637-47. doi: 10.1074/jbc.M112.346569. Epub 2012 Jun 28.
752 Hepatitis C Virus NS5A Targets Nucleosome Assembly Protein NAP1L1 To Control the Innate Cellular Response.J Virol. 2017 Aug 24;91(18):e00880-17. doi: 10.1128/JVI.00880-17. Print 2017 Sep 15.
753 Etiological role of hepatitis E virus in sporadic fulminant hepatitis.J Med Virol. 1994 Feb;42(2):133-7. doi: 10.1002/jmv.1890420207.
754 The interferon-inducible isoform of NCOA7 inhibits endosome-mediated viral entry.Nat Microbiol. 2018 Dec;3(12):1369-1376. doi: 10.1038/s41564-018-0273-9. Epub 2018 Nov 26.
755 Hepatitis C virus induces oxidative stress, DNA damage and modulates the DNA repair enzyme NEIL1.J Gastroenterol Hepatol. 2010 Mar;25(3):627-34. doi: 10.1111/j.1440-1746.2009.06128.x. Epub 2010 Jan 14.
756 Overexpression of the RD RNA binding protein in hepatitis C virus-related hepatocellular carcinoma.Oncol Rep. 2012 Aug;28(2):728-34. doi: 10.3892/or.2012.1821. Epub 2012 May 18.
757 Neuralized E3 Ubiquitin Protein Ligase 3 Is an Inducible Antiviral Effector That Inhibits Hepatitis C Virus Assembly by Targeting Viral E1 Glycoprotein.J Virol. 2018 Oct 12;92(21):e01123-18. doi: 10.1128/JVI.01123-18. Print 2018 Nov 1.
758 Hepatitis C virus core protein suppresses NF-kappaB activation and cyclooxygenase-2 expression by direct interaction with IkappaB kinase beta.J Virol. 2005 Jun;79(12):7648-57. doi: 10.1128/JVI.79.12.7648-7657.2005.
759 Genetic variation in toll-like receptors and retinoic acid-inducible gene I and outcome of hepatitis C virus infection: a candidate gene association study.J Viral Hepat. 2014 Aug;21(8):578-84. doi: 10.1111/jvh.12188. Epub 2013 Nov 13.
760 Identification of groups with poor cost-effectiveness of peginterferon plus ribavirin for nave hepatitis C patients with a real-world cohort and database.Medicine (Baltimore). 2017 Jun;96(22):e6984. doi: 10.1097/MD.0000000000006984.
761 AP-2-associated protein kinase 1 and cyclin G-associated kinase regulate hepatitis C virus entry and are potential drug targets.J Virol. 2015 Apr;89(8):4387-404. doi: 10.1128/JVI.02705-14. Epub 2015 Feb 4.
762 A comprehensive genome-wide profiling comparison between HBV and HCV infected hepatocellular carcinoma.BMC Med Genomics. 2019 Oct 28;12(1):147. doi: 10.1186/s12920-019-0580-x.
763 Functional microRNA screen uncovers O-linked N-acetylglucosamine transferase as a host factor modulating hepatitis C virus morphogenesis and infectivity.Gut. 2020 Feb;69(2):380-392. doi: 10.1136/gutjnl-2018-317423. Epub 2019 May 10.
764 Increasing Trends in Transplantation of HCV-Positive Livers Into Uninfected Recipients.Clin Gastroenterol Hepatol. 2019 Jul;17(8):1634-1636. doi: 10.1016/j.cgh.2018.09.036. Epub 2018 Sep 27.
765 Association between Cys282Tyr missense mutation and haptoglobin phenotype polymorphism in patients with chronic hepatitis C.Eur J Gastroenterol Hepatol. 2001 Sep;13(9):1077-81. doi: 10.1097/00042737-200109000-00014.
766 Inhibition of HCV replication by oxysterol-binding protein-related protein 4 (ORP4) through interaction with HCV NS5B and alteration of lipid droplet formation.PLoS One. 2013 Sep 17;8(9):e75648. doi: 10.1371/journal.pone.0075648. eCollection 2013.
767 PACSIN2 Interacts with Nonstructural Protein 5A and Regulates Hepatitis C Virus Assembly.J Virol. 2020 Feb 14;94(5):e01531-19. doi: 10.1128/JVI.01531-19. Print 2020 Feb 14.
768 Hepatitis C virus core protein induces hepatic metabolism disorders through down-regulation of the SIRT1-AMPK signaling pathway.Int J Infect Dis. 2013 Jul;17(7):e539-45. doi: 10.1016/j.ijid.2013.01.027. Epub 2013 Mar 16.
769 NS5ATP9, a gene up-regulated by HCV NS5A protein.Cancer Lett. 2008 Feb 8;259(2):192-7. doi: 10.1016/j.canlet.2007.10.029.
770 Induction of Huh? cell apoptosis by HCV core proteins via CK1p53Bid signaling pathway.Mol Med Rep. 2018 Jun;17(6):7559-7566. doi: 10.3892/mmr.2018.8844. Epub 2018 Apr 5.
771 Anti-HCV immunoblot indeterminate results in blood donors: non-specific reactivity or past exposure to HCV?.Vox Sang. 2017 Aug;112(6):542-548. doi: 10.1111/vox.12547.
772 The impact of using hepatitis c virus nucleic acid test-positive donor hearts on heart transplant waitlist time and transplant rate.J Heart Lung Transplant. 2019 Nov;38(11):1178-1188. doi: 10.1016/j.healun.2019.08.010. Epub 2019 Aug 14.
773 Genome-wide transcriptome analysis identifies novel gene signatures implicated in human chronic liver disease.Am J Physiol Gastrointest Liver Physiol. 2013 Sep 1;305(5):G364-74. doi: 10.1152/ajpgi.00077.2013. Epub 2013 Jun 27.
774 Protein Inhibitor of Activated STAT2 Restricts HCV Replication by Modulating Viral Proteins Degradation.Viruses. 2017 Sep 30;9(10):285. doi: 10.3390/v9100285.
775 Deficient Stat3 DNA-binding is associated with high Pias3 expression and a positive anti-apoptotic balance in human end-stage alcoholic and hepatitis C cirrhosis.J Hepatol. 2005 Oct;43(4):687-95. doi: 10.1016/j.jhep.2005.03.024.
776 A class II phosphoinositide 3-kinase plays an indispensable role in hepatitis C virus replication.Biochem Biophys Res Commun. 2013 Oct 11;440(1):150-6. doi: 10.1016/j.bbrc.2013.09.048. Epub 2013 Sep 18.
777 Early events in the generation of autophagosomes are required for the formation of membrane structures involved in hepatitis C virus genome replication.J Gen Virol. 2016 Mar;97(3):680-693. doi: 10.1099/jgv.0.000387. Epub 2016 Jan 4.
778 Hepatitis C virus induces the mitochondrial translocation of Parkin and subsequent mitophagy.PLoS Pathog. 2013 Mar;9(3):e1003285. doi: 10.1371/journal.ppat.1003285. Epub 2013 Mar 28.
779 Nir2 Is an Effector of VAPs Necessary for Efficient Hepatitis C Virus Replication and Phosphatidylinositol 4-Phosphate Enrichment at the Viral Replication Organelle.J Virol. 2019 Oct 29;93(22):e00742-19. doi: 10.1128/JVI.00742-19. Print 2019 Nov 15.
780 Modulation of interferon expression by hepatitis C virus NS5A protein and human homeodomain protein PTX1.Virology. 2003 Feb 1;306(1):51-9. doi: 10.1016/s0042-6822(02)00029-6.
781 Phosphatidylserine-Specific Phospholipase A1 is the Critical Bridge for Hepatitis C Virus Assembly.Virol Sin. 2019 Oct;34(5):521-537. doi: 10.1007/s12250-019-00123-2. Epub 2019 Jun 3.
782 Perilipin-2 is critical for efficient lipoprotein and hepatitis C virus particle production.J Cell Sci. 2019 Jan 9;132(1):jcs217042. doi: 10.1242/jcs.217042.
783 miR-148a and miR-30a limit HCV-dependent suppression of the lipid droplet protein, ADRP, in HCV infected cell models.J Med Virol. 2017 Apr;89(4):653-659. doi: 10.1002/jmv.24677. Epub 2016 Sep 20.
784 Perilipin 5 alleviates HCV NS5A-induced lipotoxic injuries in liver.Lipids Health Dis. 2019 Apr 6;18(1):87. doi: 10.1186/s12944-019-1022-7.
785 Interferon--Enhanced CD100/Plexin-B1/B2 Interactions Promote Natural Killer Cell Functions in Patients with Chronic Hepatitis C Virus Infection.Front Immunol. 2017 Nov 3;8:1435. doi: 10.3389/fimmu.2017.01435. eCollection 2017.
786 Off-Target Effects of Drugs that Disrupt Human Mitochondrial DNA Maintenance.Front Mol Biosci. 2017 Nov 22;4:74. doi: 10.3389/fmolb.2017.00074. eCollection 2017.
787 Development of novel triplex single-step real-time PCR assay for detection of Hepatitis Virus B and C simultaneously.Virology. 2016 May;492:101-7. doi: 10.1016/j.virol.2016.01.029. Epub 2016 Feb 22.
788 Decreased tacrolimus plasma concentrations during HCV therapy: a drug-drug interaction or is there an alternative explanation?.Int J Antimicrob Agents. 2017 Mar;49(3):379-382. doi: 10.1016/j.ijantimicag.2016.12.004. Epub 2017 Feb 6.
789 Cyclophilin B is a functional regulator of hepatitis C virus RNA polymerase.Mol Cell. 2005 Jul 1;19(1):111-22. doi: 10.1016/j.molcel.2005.05.014.
790 No evidence of the unfolded protein response in patients with chronic hepatitis C virus infection.J Gastroenterol Hepatol. 2011 Feb;26(2):319-27. doi: 10.1111/j.1440-1746.2010.06368.x.
791 Hepatitis C virus core protein modulates pRb2/p130 expression in human hepatocellular carcinoma cell lines through promoter methylation.J Exp Clin Cancer Res. 2015 Nov 14;34:140. doi: 10.1186/s13046-015-0255-1.
792 Repressing PU.1 by miR-29a?in NK cells of HCV patients, diminishes its cytolytic effect on HCV infected cell models.Hum Immunol. 2015 Sep;76(9):687-94. doi: 10.1016/j.humimm.2015.09.021. Epub 2015 Sep 30.
793 Peripheral B cells may serve as a reservoir for persistent hepatitis C virus infection.J Innate Immun. 2010;2(6):607-17. doi: 10.1159/000317690. Epub 2010 Aug 17.
794 A rare and severe cutaneous adverse effect of telaprevir: drug rash with eosinophilia and systemic symptoms.G Ital Dermatol Venereol. 2019 Aug;154(4):488-491. doi: 10.23736/S0392-0488.17.05151-3.
795 N-terminal HCV core protein fragment decreases 20S proteasome activity in the presence of PA28.Biochem Biophys Res Commun. 2019 Feb 5;509(2):590-595. doi: 10.1016/j.bbrc.2018.12.167. Epub 2018 Dec 31.
796 Focal adhesion kinase (FAK) mediates the induction of pro-oncogenic and fibrogenic phenotypes in hepatitis C virus (HCV)-infected cells.PLoS One. 2012;7(8):e44147. doi: 10.1371/journal.pone.0044147. Epub 2012 Aug 28.
797 Quinolinate Phosphoribosyltransferase is an Antiviral Host Factor Against Hepatitis C Virus Infection.Sci Rep. 2017 Jul 19;7(1):5876. doi: 10.1038/s41598-017-06254-4.
798 Rab18 binds to hepatitis C virus NS5A and promotes interaction between sites of viral replication and lipid droplets.PLoS Pathog. 2013;9(8):e1003513. doi: 10.1371/journal.ppat.1003513. Epub 2013 Aug 1.
799 Role for TBC1D20 and Rab1 in hepatitis C virus replication via interaction with lipid droplet-bound nonstructural protein 5A.J Virol. 2012 Jun;86(12):6491-502. doi: 10.1128/JVI.00496-12. Epub 2012 Apr 4.
800 Differential Regulation of Lipoprotein and Hepatitis C Virus Secretion by Rab1b.Cell Rep. 2017 Oct 10;21(2):431-441. doi: 10.1016/j.celrep.2017.09.053.
801 Roles for endocytic trafficking and phosphatidylinositol 4-kinase III alpha in hepatitis C virus replication.Proc Natl Acad Sci U S A. 2009 May 5;106(18):7577-82. doi: 10.1073/pnas.0902693106. Epub 2009 Apr 17.
802 Hepatitis C Virus-Induced Rab32 Aggregation and Its Implications for Virion Assembly.J Virol. 2017 Jan 18;91(3):e01662-16. doi: 10.1128/JVI.01662-16. Print 2017 Feb 1.
803 Hepatitis C virus Core protein overcomes all-trans retinoic acid-induced cell growth arrest by inhibiting retinoic acid receptor-2 expression via DNA methylation.Cancer Lett. 2013 Jul 28;335(2):372-9. doi: 10.1016/j.canlet.2013.02.057. Epub 2013 Mar 6.
804 Rab5 Enhances Classical Swine Fever Virus Proliferation and Interacts with Viral NS4B Protein to Facilitate Formation of NS4B Related Complex.Front Microbiol. 2017 Aug 8;8:1468. doi: 10.3389/fmicb.2017.01468. eCollection 2017.
805 Nonstructural Protein 5A Impairs DNA Damage Repair: Implications for Hepatitis C Virus-Mediated Hepatocarcinogenesis.J Virol. 2018 May 14;92(11):e00178-18. doi: 10.1128/JVI.00178-18. Print 2018 Jun 1.
806 Discovery and Validation of a Biomarker Model (PRESERVE) Predictive of Renal Outcomes After Liver Transplantation.Hepatology. 2020 May;71(5):1775-1786. doi: 10.1002/hep.30939. Epub 2020 Jan 28.
807 Human Endogenous Retrovirus-K HML-2 integration within RASGRF2 is associated with intravenous drug abuse and modulates transcription in a cell-line model.Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10434-10439. doi: 10.1073/pnas.1811940115. Epub 2018 Sep 24.
808 RNA binding protein 24 regulates the translation and replication of hepatitis C virus.Protein Cell. 2018 Nov;9(11):930-944. doi: 10.1007/s13238-018-0507-x. Epub 2018 Jan 30.
809 Hepatitis C virus core protein fused to hepatitis B virus core antigen for serological diagnosis of both hepatitis C and hepatitis B infections by ELISA.J Med Virol. 1999 Feb;57(2):104-10.
810 Novel differential gene expression in human cirrhosis detected by suppression subtractive hybridization.Hepatology. 2003 Sep;38(3):577-88. doi: 10.1053/jhep.2003.50376.
811 Impaired interferon signaling in chronic hepatitis C patients with advanced fibrosis via the transforming growth factor beta signaling pathway.Hepatology. 2014 Nov;60(5):1519-30. doi: 10.1002/hep.27277. Epub 2014 Oct 2.
812 Direct detection of circulating hepatitis C virus RNA using probes from the 5' untranslated region.J Clin Invest. 1992 Jun;89(6):2040-5. doi: 10.1172/JCI115815.
813 TRC8-dependent degradation of hepatitis C virus immature core protein regulates viral propagation and pathogenesis.Nat Commun. 2016 May 4;7:11379. doi: 10.1038/ncomms11379.
814 A randomized, double-blind, placebo-controlled assessment of BMS-936558, a fully human monoclonal antibody to programmed death-1 (PD-1), in patients with chronic hepatitis C virus infection.PLoS One. 2013 May 22;8(5):e63818. doi: 10.1371/journal.pone.0063818. Print 2013.
815 In vitro selection of the 3'-untranslated regions of the human liver mRNA that bind to the HCV nonstructural protein 5B.Virology. 2014 Feb;450-451:13-23. doi: 10.1016/j.virol.2013.11.036. Epub 2013 Dec 18.
816 Attenuation of 40S ribosomal subunit abundance differentially affects host and HCV translation and suppresses HCV replication.PLoS Pathog. 2012 Jun;8(6):e1002766. doi: 10.1371/journal.ppat.1002766. Epub 2012 Jun 28.
817 A naturally occurring antiviral ribonucleotide encoded by the human genome.Nature. 2018 Jun;558(7711):610-614. doi: 10.1038/s41586-018-0238-4. Epub 2018 Jun 20.
818 Long-term effects of the new direct antiviral agents (DAAs) therapy for HCV-related mixed cryoglobulinaemia without renal involvement: a multicentre open-label study.Clin Exp Rheumatol. 2018 Mar-Apr;36 Suppl 111(2):107-114. Epub 2018 Feb 13.
819 Understanding the biological context of NS5A-host interactions in HCV infection: a network-based approach.J Proteome Res. 2013 Jun 7;12(6):2537-51. doi: 10.1021/pr3011217. Epub 2013 May 17.
820 Up-regulation of Hedgehog pathway is associated with cellular permissiveness for hepatitis C virus replication.Hepatology. 2011 Nov;54(5):1580-90. doi: 10.1002/hep.24576.
821 Treatment of hepatitis C virus core-positive hepatocytes with the transfer of recombinant caspase-3 using the 2',5'-oligoadenylate synthetase gene promoter.Acta Biochim Biophys Sin (Shanghai). 2009 Jul;41(7):554-60. doi: 10.1093/abbs/gmp044.
822 SEC14L2, a lipid-binding protein, regulates HCV replication in culture with inter- and intra-genotype variations.J Hepatol. 2019 Apr;70(4):603-614. doi: 10.1016/j.jhep.2018.11.012. Epub 2018 Nov 23.
823 Sec24C-Dependent Transport of Claudin-1 Regulates Hepatitis C Virus Entry.J Virol. 2017 Aug 24;91(18):e00629-17. doi: 10.1128/JVI.00629-17. Print 2017 Sep 15.
824 microRNAs: Key players in virus-associated hepatocellular carcinoma.J Cell Physiol. 2019 Aug;234(8):12188-12225. doi: 10.1002/jcp.27956. Epub 2018 Dec 7.
825 Squamous cell carcinoma antigen-1 (SERPINB3) polymorphism in chronic liver disease.Dig Liver Dis. 2009 Mar;41(3):212-6. doi: 10.1016/j.dld.2008.06.001. Epub 2008 Jul 25.
826 Promoter hypermethylation of Wnt pathway inhibitors in hepatitis C virus - induced multistep hepatocarcinogenesis.Virol J. 2014 Jun 20;11:117. doi: 10.1186/1743-422X-11-117.
827 Structure-function analysis of the equine hepacivirus 5' untranslated region highlights the conservation of translational mechanisms across the hepaciviruses.J Gen Virol. 2019 Nov;100(11):1501-1514. doi: 10.1099/jgv.0.001316.
828 Hepatitis C virus core protein represses p21WAF1/Cip1/Sid1 promoter activity.Gene. 1998 Feb 27;208(2):331-6. doi: 10.1016/s0378-1119(98)00030-4.
829 Altered Peripheral Blood Monocyte Phenotype and Function in Chronic Liver Disease: Implications for Hepatic Recruitment and Systemic Inflammation.PLoS One. 2016 Jun 16;11(6):e0157771. doi: 10.1371/journal.pone.0157771. eCollection 2016.
830 Detection of the hepatitis C virus antigen in kidney tissue from infected patients with various glomerulonephritis.Nephrol Dial Transplant. 2009 Sep;24(9):2745-51. doi: 10.1093/ndt/gfp167. Epub 2009 Apr 17.
831 Real-world effectiveness and safety of sofosbuvir/velpatasvir and ledipasvir/sofosbuvir hepatitis C treatment in a single centre in Germany.PLoS One. 2019 Apr 4;14(4):e0214795. doi: 10.1371/journal.pone.0214795. eCollection 2019.
832 Ledipasvir/sofosbuvir with or without ribavirin for the treatment of chronic hepatitis C genotype 1: A pairwise meta-analysis.J Gastroenterol Hepatol. 2017 Apr;32(4):749-755. doi: 10.1111/jgh.13620.
833 Invivo treatment of HCV core-positive HepG2 cells with the transfer of recombinant caspase-3 using a 2'-5' OAS promoter.Mol Med Rep. 2012 Mar;5(3):631-6. doi: 10.3892/mmr.2011.703. Epub 2011 Dec 9.
834 Pivotal role for the ESCRT-II complex subunit EAP30/SNF8 in IRF3-dependent innate antiviral defense.PLoS Pathog. 2017 Oct 30;13(10):e1006713. doi: 10.1371/journal.ppat.1006713. eCollection 2017 Oct.
835 Hepatitis C virus nonstructural protein NS3 binds to Sm-D1, a small nuclear ribonucleoprotein associated with autoimmune disease.Microbiol Immunol. 2003;47(8):601-11. doi: 10.1111/j.1348-0421.2003.tb03423.x.
836 Hepatitis C virus recombinants are rare even among intravenous drug users.J Med Virol. 2010 Feb;82(2):232-8. doi: 10.1002/jmv.21631.
837 Aberrant methylation of promoter region of SPINT2/HAI-2 gene: an epigenetic mechanism in hepatitis C virus-induced hepatocarcinogenesis.Genet Test Mol Biomarkers. 2015 Jul;19(7):399-404. doi: 10.1089/gtmb.2015.0025. Epub 2015 Jun 1.
838 Hepatitis GBV-C sequences in patients infected with HCV contaminated anti-D immunoglobulin and among i.v. drug users in Germany.J Hepatol. 1996 Sep;25(3):385-9. doi: 10.1016/s0168-8278(96)80126-7.
839 SPSB2 inhibits hepatitis C virus replication by targeting NS5A for ubiquitination and degradation.PLoS One. 2019 Jul 25;14(7):e0219989. doi: 10.1371/journal.pone.0219989. eCollection 2019.
840 Anti-SSB/La antibody is negatively associated with HLA-DR2 in chronic hepatitis C infection.Clin Rheumatol. 2008 Mar;27(3):365-8. doi: 10.1007/s10067-007-0783-y. Epub 2007 Nov 9.
841 Hepatitis C virus core protein reduces CD8(+) T-cell proliferation, perforin production and degranulation but increases STAT5 activation.Immunology. 2018 May;154(1):156-165. doi: 10.1111/imm.12882. Epub 2018 Jan 25.
842 Staufen1 promotes HCV replication by inhibiting protein kinase R and transporting viral RNA to the site of translation and replication in the cells.Nucleic Acids Res. 2016 Jun 20;44(11):5271-87. doi: 10.1093/nar/gkw312. Epub 2016 Apr 22.
843 Hepatitis C virus NS4B blocks the interaction of STING and TBK1 to evade host innate immunity.J Hepatol. 2013 Jul;59(1):52-8. doi: 10.1016/j.jhep.2013.03.019. Epub 2013 Mar 28.
844 Identification of syntaxin 4 as an essential factor for the hepatitis C virus life cycle.Eur J Cell Biol. 2017 Sep;96(6):542-552. doi: 10.1016/j.ejcb.2017.06.002. Epub 2017 Jun 10.
845 HCV-induced autophagosomes are generated via homotypic fusion of phagophores that mediate HCV RNA replication.PLoS Pathog. 2017 Sep 19;13(9):e1006609. doi: 10.1371/journal.ppat.1006609. eCollection 2017 Sep.
846 Surfeit 4 Contributes to the Replication of Hepatitis C Virus Using Double-Membrane Vesicles.J Virol. 2020 Jan 6;94(2):e00858-19. doi: 10.1128/JVI.00858-19. Print 2020 Jan 6.
847 Histone-modifying genes as biomarkers in hepatocellular carcinoma.Int J Clin Exp Pathol. 2014 Apr 15;7(5):2496-507. eCollection 2014.
848 Evaluation of Safety and Effectiveness of Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Switch Followed by Ledipasvir/Sofosbuvir HCV Therapy in HIV-HCV Coinfection.Open Forum Infect Dis. 2019 Jul 1;6(7):ofz318. doi: 10.1093/ofid/ofz318.
849 Reducing Agent-Assisted Excessive Galvanic Replacement Mediated Seed-Mediated Synthesis of Porous Gold Nanoplates and Highly Efficient Gene-Thermo Cancer Therapy.ACS Appl Mater Interfaces. 2017 Oct 11;9(40):35268-35278. doi: 10.1021/acsami.7b13028. Epub 2017 Oct 2.
850 HCV NS5A interacts with p53 and inhibits p53-mediated apoptosis.Oncogene. 2002 Jul 18;21(31):4801-11. doi: 10.1038/sj.onc.1205589.
851 Expression of thioredoxin and thioredoxin-binding protein-2 in the liver of patients with chronic hepatitis C as a predictor of response to interferon therapy.Int J Mol Med. 2006 Jun;17(6):989-95.
852 The MMP1 (-16071G/2G) single nucleotide polymorphism associates with the HAART-related lipodystrophic syndrome.AIDS. 2010 Oct 23;24(16):2499-506. doi: 10.1097/QAD.0b013e32833e922c.
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856 Pleiotropy and allelic heterogeneity in the TOMM40-APOE genomic region related to clinical and metabolic features of hepatitis C infection.Hum Genet. 2012 Dec;131(12):1911-20. doi: 10.1007/s00439-012-1220-0. Epub 2012 Aug 17.
857 TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection.Nature. 2019 Jul;571(7764):265-269. doi: 10.1038/s41586-019-1326-9. Epub 2019 Jun 17.
858 Telaprevir activity in treatment-naive patients infected hepatitis C virus genotype 4: a randomized trial.J Infect Dis. 2013 Sep;208(6):1000-7. doi: 10.1093/infdis/jit274. Epub 2013 Jun 24.
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862 TRIM14 inhibits hepatitis C virus infection by SPRY domain-dependent targeted degradation of the viral NS5A protein.Sci Rep. 2016 Aug 31;6:32336. doi: 10.1038/srep32336.
863 TRIM56 is an essential component of the TLR3 antiviral signaling pathway.J Biol Chem. 2012 Oct 19;287(43):36404-13. doi: 10.1074/jbc.M112.397075. Epub 2012 Sep 4.
864 Potent viral suppression and improvements in alpha-fetoprotein and measures of fibrosis in Japanese patients receiving a daclatasvir/asunaprevir/beclabuvir fixed-dose combination for the treatment of HCV genotype-1 infection.J Gastroenterol. 2018 Sep;53(9):1089-1097. doi: 10.1007/s00535-018-1445-3. Epub 2018 Mar 2.
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866 A common polymorphism in the NCAN gene is associated with hepatocellular carcinoma in alcoholic liver disease.J Hepatol. 2014 Nov;61(5):1073-9. doi: 10.1016/j.jhep.2014.06.006. Epub 2014 Jun 16.
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