Details of Disease

General Information of Disease (ID: DISDW8R6)

Disease Name	Skin disease
Synonyms	dermatosis; genodermatosis; disease of zone of skin; disorder of zone of skin; skin diseases and manifestations; skin disorder; disorder of skin; disease or disorder of zone of skin; zone of skin disease or disorder; skin and subcutaneous tissue disease; zone of skin disease; cutaneous disorder
Disease Class	EA00-EM0Z: Skin disease
Definition	Any deviation from the normal structure or function of the skin or subcutaneous tissue that is manifested by a characteristic set of symptoms and signs.
Disease Hierarchy	DISTXWNT: Integumentary system disorder DISWD40R: Disease DISDW8R6: Skin disease
ICD Code	ICD-11 ICD-11: EA00-EM0Z ICD-10 ICD-10: L00-L99
Disease Identifiers	MONDO ID MONDO_0005093 MESH ID D012871 UMLS CUI C0037274 MedGen ID 20777 SNOMED CT ID 95320005

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 11 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Ammonium lactate	DMXMHBB	Approved	Small molecular drug	[1]
Betamethasone	DMAHJEF	Approved	Small molecular drug	[2]
Cortisone Acetate	DMG8K57	Approved	Small molecular drug	[3]
Dexamethasone	DMMWZET	Approved	Small molecular drug	[4]
Dexpanthenol	DMUTSRW	Approved	Small molecular drug	[5]
Halcinonide	DMGLAX1	Approved	Small molecular drug	[6]
Methylprednisolone	DM4BDON	Approved	Small molecular drug	[7]
Prednisolone	DMQ8FR2	Approved	Small molecular drug	[8]
Prednisone	DM2HG4X	Approved	Small molecular drug	[9]
Triamcinolone	DM98IXF	Approved	Small molecular drug	[10]
Urea	DMUK75B	Approved	Small molecular drug	[11]
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⏷ Show the Full List of 11 Drug(s)

This Disease is Treated as An Indication in 3 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
SD-101	DMAMTGI	Phase 3	Oligonucleotide	[12]
AR28	DMYMKAY	Phase 2	NA	[13]
BIZELESIN	DMX9ER7	Phase 1	Small molecular drug	[14]
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This Disease is Treated as An Indication in 4 Patented Agent(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
1-hydroxyl-3,5-bis(4-hydroxylstyryl)benzene derivative 1	DMK75BT	Patented	Small molecular drug	[15]
1-hydroxyl-3,5-bis(4-hydroxylstyryl)benzene derivative 2	DMIWQZ5	Patented	Small molecular drug	[15]
1-hydroxyl-3,5-bis(4-hydroxylstyryl)benzene derivative 3	DMNXAUZ	Patented	Small molecular drug	[15]
1-hydroxyl-3,5-bis(4-hydroxylstyryl)benzene derivative 4	DMV2W9Z	Patented	Small molecular drug	[15]
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This Disease is Treated as An Indication in 1 Investigative Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Sulforaphane	DMQY3L0	Investigative	NA	[16]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 101 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
ATP2A2	TTE6THL	Limited	Genetic Variation	[17]
CCL20	TT2XAZY	Limited	Biomarker	[18]
CD44	TTWFBT7	Limited	Biomarker	[19]
EPHA4	TTG84D3	Limited	Altered Expression	[20]
F2RL1	TTQR74A	Limited	Biomarker	[21]
GJB6	TTAU8SJ	Limited	Genetic Variation	[22]
GZMB	TTKEPHX	Limited	Altered Expression	[23]
IL20	TTNZMY2	Limited	Biomarker	[24]
NLRP1	TTQX29T	Limited	Genetic Variation	[25]
PDE4A	TTZ97H5	Limited	Altered Expression	[26]
RHBDF2	TTH1ZOP	Limited	Biomarker	[16]
SCD	TT6RIOV	Limited	Biomarker	[27]
TGM1	TT7A949	Limited	Genetic Variation	[28]
TRPV3	TT946IA	Limited	Biomarker	[29]
GJB3	TTVRQ8L	Disputed	Genetic Variation	[30]
MTHFR	TTQWOU1	Disputed	Biomarker	[31]
TNF	TTF8CQI	Disputed	Biomarker	[32]
BACH1	TT2ME4S	moderate	Biomarker	[33]
CAMP	TTULOB6	moderate	Altered Expression	[34]
IFNA2	TTSIUJ9	moderate	Biomarker	[35]
IL19	TT87RWS	moderate	Biomarker	[24]
KLK5	TTULSEW	moderate	Altered Expression	[34]
LAMC2	TTNS7H3	moderate	Genetic Variation	[36]
ACKR1	TTKY2NS	Strong	Biomarker	[37]
ALOX12	TT12ABZ	Strong	Biomarker	[38]
ALOX12B	TTQ4QQH	Strong	Biomarker	[39]
AQP3	TTLDNMQ	Strong	Biomarker	[40]
AREG	TT76B3W	Strong	Biomarker	[41]
BLVRA	TTJBPN3	Strong	Biomarker	[42]
CCL17	TTMPHAE	Strong	Biomarker	[43]
CCL22	TTBTWI1	Strong	Biomarker	[44]
CD1A	TTBGTFN	Strong	Biomarker	[45]
CD83	TTT9MRQ	Strong	Biomarker	[19]
COL7A1	TTBCOKN	Strong	Genetic Variation	[46]
CXCL2	TTZF0K2	Strong	Biomarker	[19]
DCPS	TTLSW9V	Strong	Genetic Variation	[47]
DPP9	TTNDUL7	Strong	Biomarker	[48]
DSG3	TTEO4P8	Strong	Biomarker	[49]
EIF2AK1	TTRUJBV	Strong	Altered Expression	[50]
ENPP2	TTSCIM2	Strong	Biomarker	[51]
EPHA5	TTV9KOD	Strong	Genetic Variation	[52]
FCAR	TTGUJAO	Strong	Biomarker	[53]
FGFR2	TTGJVQM	Strong	Biomarker	[38]
FKBP1A	TTMW94E	Strong	Biomarker	[54]
GADD45B	TTMDW9L	Strong	Biomarker	[19]
GBA	TT1B5PU	Strong	Altered Expression	[55]
GJB4	TTBRDFI	Strong	Genetic Variation	[56]
GSTO1	TTWO3SH	Strong	Biomarker	[57]
HRH4	TTXJ178	Strong	Biomarker	[58]
ID2	TTW8A5N	Strong	Biomarker	[19]
IL13	TT0GVCH	Strong	Biomarker	[59]
IL13RA1	TTNEAMG	Strong	Biomarker	[60]
IL17A	TTG0MT6	Strong	Biomarker	[61]
IL1R1	TTWOTEA	Strong	Biomarker	[38]
IL1RN	TT6GSR3	Strong	Biomarker	[19]
IL22	TTLDX4N	Strong	Biomarker	[62]
IL31	TT1RJXK	Strong	Biomarker	[63]
IL33	TT5MD4P	Strong	Biomarker	[64]
IL7	TT8FRMO	Strong	Biomarker	[65]
ITGA1	TTPERWV	Strong	Altered Expression	[66]
ITGB2	TTIJWR7	Strong	Biomarker	[67]
ITK	TT3C80U	Strong	Biomarker	[68]
KCNJ2	TTH7UO3	Strong	Biomarker	[19]
KLK14	TTDA81R	Strong	Altered Expression	[69]
KLK6	TTLPF4X	Strong	Biomarker	[70]
KLK7	TTE6GTB	Strong	Altered Expression	[69]
KLKB1	TTN0PCX	Strong	Genetic Variation	[71]
KRT17	TTKV0EC	Strong	Biomarker	[72]
KRT6A	TT2FX8W	Strong	Genetic Variation	[73]
LAIR1	TTSI7A8	Strong	Altered Expression	[74]
LAMB3	TT2WOUQ	Strong	Genetic Variation	[75]
LIMK1	TTWL9TY	Strong	Altered Expression	[76]
LYZ	TTAOZBW	Strong	Biomarker	[77]
MC1R	TT0MV2T	Strong	Genetic Variation	[78]
MMP21	TTYRF5E	Strong	Biomarker	[79]
MVK	TT5DFHW	Strong	Genetic Variation	[80]
NEDD4	TT1QU6G	Strong	Biomarker	[81]
NR4A2	TT9HKN3	Strong	Biomarker	[19]
OGG1	TTRU01G	Strong	Biomarker	[82]
ORAI1	TTE76YK	Strong	Biomarker	[83]
OSMR	TTAH0KM	Strong	Biomarker	[60]
PDE4B	TTVIAT9	Strong	Biomarker	[19]
PFKFB3	TTTHMQJ	Strong	Biomarker	[19]
POSTN	TT8ALTZ	Strong	Biomarker	[84]
PRSS8	TTT4N0Q	Strong	Biomarker	[85]
RIPK4	TTB4S01	Strong	Biomarker	[86]
RORA	TT1TYN7	Strong	Biomarker	[87]
SELPLG	TTS5K8U	Strong	Biomarker	[88]
SLC27A4	TT20AYF	Strong	Genetic Variation	[89]
TNFRSF14	TTWGTC1	Strong	Biomarker	[37]
TNFRSF17	TTZ3P4W	Strong	Biomarker	[90]
TNIK	TTPB1W3	Strong	Biomarker	[19]
TRB	TT84HCW	Strong	Biomarker	[91]
TRBC1	TT1DHW2	Strong	Biomarker	[91]
TRPV6	TTBK14N	Strong	Biomarker	[92]
TSHR	TT6NYJA	Strong	Biomarker	[93]
TSLP	TTHMW3T	Strong	Altered Expression	[94]
TXK	TT8M1DP	Strong	Biomarker	[68]
TYR	TTULVH8	Strong	Biomarker	[95]
USP13	TTVJIO2	Strong	Biomarker	[19]
CBL	TT7QT13	Definitive	Altered Expression	[96]
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⏷ Show the Full List of 101 DTT(s)

This Disease Is Related to 2 DTP Molecule(s)

Gene Name	DTP ID	Evidence Level	Mode of Inheritance	REF
ABCA12	DT7LDG0	Limited	Genetic Variation	[97]
SLC29A3	DTZAWTH	Limited	Genetic Variation	[98]
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This Disease Is Related to 11 DME Molecule(s)

Gene Name	DME ID	Evidence Level	Mode of Inheritance	REF
NAT10	DEZV4AP	Limited	Biomarker	[99]
TGM5	DEW8QEH	Disputed	Biomarker	[100]
CYP2S1	DE6NMGO	moderate	Altered Expression	[101]
CYB5A	DE9A2LB	Strong	Biomarker	[102]
GSTM1	DEYZEJA	Strong	Biomarker	[103]
MINPP1	DE5Q1SP	Strong	Biomarker	[19]
MSMO1	DE5FUD0	Strong	Genetic Variation	[104]
PGM1	DEA3VM1	Strong	Genetic Variation	[105]
SULT2A1	DE0P6LK	Strong	Biomarker	[106]
TGM3	DEOEB3Q	Strong	Biomarker	[107]
TPMT	DEFQ8VO	Strong	Biomarker	[108]
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⏷ Show the Full List of 11 DME(s)

This Disease Is Related to 151 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
AAGAB	OTRGGM2Z	Limited	Genetic Variation	[109]
ADAR	OTQNOHR8	Limited	Genetic Variation	[110]
ATP2C1	OTQN51T3	Limited	Genetic Variation	[111]
CCRL2	OT5PX0RX	Limited	Biomarker	[19]
CRABP2	OTY01V9G	Limited	Altered Expression	[112]
DSP	OTB2MOP8	Limited	Genetic Variation	[113]
IL17B	OTS86H50	Limited	Biomarker	[24]
KRT1	OTIOJWA4	Limited	Genetic Variation	[114]
KRT14	OTUVZ1DW	Limited	Genetic Variation	[115]
PLEC	OTU4XDEG	Limited	Genetic Variation	[116]
RBP2	OTR8QG5V	Limited	Altered Expression	[112]
SDC4	OTKUVUGZ	Limited	Altered Expression	[117]
CDSN	OTQW4HV6	Disputed	Genetic Variation	[118]
KL	OTD4VWU6	Disputed	Biomarker	[119]
SHOC2	OTUNQ2CT	Disputed	Biomarker	[120]
NUDT15	OTX8SZOT	moderate	Genetic Variation	[121]
AIM2	OT86QUI8	Strong	Biomarker	[122]
AKAP9	OT7Z2YRP	Strong	Biomarker	[19]
AP1S3	OTPCMV24	Strong	Genetic Variation	[123]
APBA2	OTXD8ID1	Strong	Biomarker	[124]
APOBEC3C	OTPL0AI1	Strong	Biomarker	[125]
ATP2A1	OT959A3A	Strong	Genetic Variation	[126]
ATXN7	OTL3YF1H	Strong	Biomarker	[19]
CALML5	OTOFJLFA	Strong	Biomarker	[107]
CAMK4	OT47RDGV	Strong	Biomarker	[127]
CARD14	OTADQHOV	Strong	Genetic Variation	[128]
CARD18	OTBMLB80	Strong	Altered Expression	[129]
CARD9	OTJ81AWD	Strong	Biomarker	[130]
CCL18	OT7JYSK9	Strong	Altered Expression	[131]
CCL28	OTY6XNQ7	Strong	Biomarker	[132]
CCL4	OT6B8P25	Strong	Biomarker	[19]
CCNH	OTKDU3SR	Strong	Genetic Variation	[109]
CCR10	OT7ZWSSD	Strong	Biomarker	[133]
CD1D	OT3ROU4J	Strong	Biomarker	[134]
CETN1	OTGQ8JOZ	Strong	Biomarker	[135]
CIAPIN1	OTWS90F9	Strong	Biomarker	[136]
CLDN3	OT71MN9S	Strong	Biomarker	[137]
COL17A1	OTID5AH2	Strong	Biomarker	[138]
CST6	OTZVHJTF	Strong	Biomarker	[139]
CXCL3	OTSL94KH	Strong	Biomarker	[19]
DCD	OTV5PBGJ	Strong	Biomarker	[140]
DMKN	OTRIGZMK	Strong	Altered Expression	[141]
DOCK8	OTNQLL21	Strong	Biomarker	[142]
DSC2	OTODVH8K	Strong	Biomarker	[143]
DSC3	OTYG47F8	Strong	Biomarker	[143]
DSG1	OT11HC3A	Strong	Biomarker	[144]
DST	OTHZBM4X	Strong	Biomarker	[145]
ECM1	OT1K65VW	Strong	Biomarker	[146]
EIF2B5	OTV3R4RB	Strong	Biomarker	[147]
ELN	OTFSO7PG	Strong	Biomarker	[148]
EMCN	OTS03CZC	Strong	Altered Expression	[149]
ERCC2	OT1C8HQ4	Strong	Biomarker	[150]
ERCC3	OTVAW3P1	Strong	Altered Expression	[151]
EXOSC10	OTH8Z0AL	Strong	Biomarker	[152]
FCGR2C	OTNLMNYB	Strong	Genetic Variation	[153]
FERMT1	OT626PBA	Strong	Genetic Variation	[154]
FLG	OTE9QDV6	Strong	Altered Expression	[155]
GADD45G	OT8V1J4M	Strong	Genetic Variation	[156]
GALNTL5	OT93QQKE	Strong	Biomarker	[124]
GOLGA4	OTCMEHNJ	Strong	Biomarker	[19]
GTF2H2	OTK72L9I	Strong	Altered Expression	[151]
GTF2H3	OT87W5QJ	Strong	Genetic Variation	[109]
GTF2H4	OTPD1DIU	Strong	Altered Expression	[151]
GTF2H5	OTRL219S	Strong	Altered Expression	[151]
HOPX	OTBSR6C9	Strong	Altered Expression	[157]
HOXB4	OTH1HRW5	Strong	Altered Expression	[158]
ID4	OTPMJ39I	Strong	Biomarker	[159]
IER3	OTZJI5FZ	Strong	Biomarker	[19]
IGFL1	OT0QQU8C	Strong	Biomarker	[160]
IGFLR1	OTPUCWQR	Strong	Biomarker	[160]
IL22RA2	OTGOFDCY	Strong	Altered Expression	[161]
IL26	OT2WYCW4	Strong	Biomarker	[162]
IL36RN	OT5CO95A	Strong	Genetic Variation	[163]
INPP5A	OT9CMGMS	Strong	Biomarker	[164]
IRF2	OTAZRUW3	Strong	Biomarker	[165]
ITGA3	OTBCH21D	Strong	Genetic Variation	[166]
ITIH5	OTP46PZM	Strong	Altered Expression	[167]
IVL	OT4VPNGY	Strong	Biomarker	[168]
KDSR	OTCIES3H	Strong	Genetic Variation	[169]
KRT10	OTSVRD3Q	Strong	Genetic Variation	[170]
KRT16	OTGA0EQN	Strong	Altered Expression	[171]
KRT5	OTVGI9HT	Strong	Genetic Variation	[172]
KRT76	OT2V7AP3	Strong	Biomarker	[173]
KRT9	OTA10UCH	Strong	Altered Expression	[174]
LAD1	OT6YGTVX	Strong	Biomarker	[138]
LAIR2	OTKCADXC	Strong	Altered Expression	[74]
LAMA3	OTFME7HT	Strong	Genetic Variation	[175]
LEMD3	OTILAM4I	Strong	Genetic Variation	[176]
LORICRIN	OTFRPVEO	Strong	Genetic Variation	[177]
LRRC59	OT6BQJ5E	Strong	Genetic Variation	[109]
MCM5	OTAHLB62	Strong	Altered Expression	[178]
MMP26	OT9O89KU	Strong	Biomarker	[79]
MORC3	OT81NKVT	Strong	Biomarker	[179]
N4BP2L2	OTV2F04G	Strong	Biomarker	[19]
NAT9	OT4ZKCRS	Strong	Genetic Variation	[172]
NCSTN	OT5QBTA4	Strong	Genetic Variation	[180]
NDUFB8	OTW4A4Q0	Strong	Biomarker	[19]
NME2	OTCYGLHV	Strong	Altered Expression	[181]
NTM	OTHF0UQU	Strong	Biomarker	[182]
OR5J2	OTS5WAIJ	Strong	Biomarker	[124]
PARP14	OTFXJAKK	Strong	Biomarker	[183]
PDZK1IP1	OTWA6M5K	Strong	Altered Expression	[184]
PELI1	OTMLBCLC	Strong	Biomarker	[19]
PHB2	OTCAX3AW	Strong	Genetic Variation	[185]
PI3	OT47MTC3	Strong	Biomarker	[186]
PIAS1	OTZVAHZI	Strong	Biomarker	[19]
PLAAT4	OTI66SAJ	Strong	Altered Expression	[187]
PLCD1	OT6WFVXZ	Strong	Biomarker	[188]
POF1B	OTFWNK8G	Strong	Biomarker	[189]
POFUT1	OTOBJZIT	Strong	Genetic Variation	[190]
POMP	OTMPM1P5	Strong	Genetic Variation	[191]
PPP1R13L	OTNCPLWE	Strong	Genetic Variation	[192]
PTPRA	OTZA82J1	Strong	Biomarker	[193]
PTX3	OTPXHRKU	Strong	Biomarker	[19]
RFX3	OTE0EI8Z	Strong	Biomarker	[19]
RGS1	OTGXJYMG	Strong	Biomarker	[19]
RNASE7	OTIXO0Z4	Strong	Biomarker	[194]
RTRAF	OTJ6NVMW	Strong	Biomarker	[147]
RUFY3	OTMA4YA4	Strong	Biomarker	[19]
S100A14	OTVFJJ91	Strong	Altered Expression	[135]
S100A7	OTJFVJRF	Strong	Altered Expression	[195]
S100A7A	OTNM8DCP	Strong	Altered Expression	[135]
SAGE1	OT4H6FFA	Strong	Altered Expression	[196]
SDF4	OTQ7WFYW	Strong	Biomarker	[135]
SFPQ	OTLCIAPJ	Strong	Biomarker	[19]
SGCZ	OTVGTEOD	Strong	Biomarker	[124]
SIGLEC14	OT2JGGXD	Strong	Genetic Variation	[197]
SKIL	OTNBXH32	Strong	Biomarker	[19]
SMG1	OTTS3SXE	Strong	Biomarker	[51]
SMR3A	OT6NAJJI	Strong	Biomarker	[125]
SOX18	OTPUMHWA	Strong	Biomarker	[19]
SPINK5	OT61IIAO	Strong	Genetic Variation	[198]
SPINK7	OTK3VOI3	Strong	Biomarker	[199]
SPRR1B	OTXNW3P6	Strong	Altered Expression	[200]
SPRR3	OTN9QJKG	Strong	Altered Expression	[200]
SRP68	OTZ7HIID	Strong	Biomarker	[19]
SSBP1	OTH2PZWH	Strong	Biomarker	[19]
TAF1D	OTOXUDV1	Strong	Biomarker	[19]
TCHH	OT4J7EFT	Strong	Biomarker	[201]
TENM1	OTSKSU4V	Strong	Biomarker	[202]
TMX1	OTX4FHYQ	Strong	Biomarker	[203]
TNFAIP6	OT1SLUZH	Strong	Biomarker	[19]
TNFSF8	OTDYGDJ3	Strong	Biomarker	[204]
TNIP1	OTRAOTEW	Strong	Biomarker	[205]
TOX	OTE8BL5Z	Strong	Altered Expression	[206]
TRA2A	OT5NHOO3	Strong	Biomarker	[19]
TRAPPC10	OTF6EAQX	Strong	Biomarker	[19]
TRIM21	OTA4UJCF	Strong	Altered Expression	[207]
CCL27	OTUZYC61	Definitive	Biomarker	[208]
CXCL17	OTRCEVIZ	Definitive	Biomarker	[209]
HLA-C	OTV38BUJ	Definitive	Genetic Variation	[210]
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⏷ Show the Full List of 151 DOT(s)

References

1	Ammonium lactate FDA Label
2	Betamethasone FDA Label
3	Cortisone acetate FDA Label
4	Dexamethasone FDA Label
5	Riboflavin FDA Label
6	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
7	Methylprednisolone FDA Label
8	Prednisolone FDA Label
9	Prednisone FDA Label
10	Triamcinolone FDA Label
11	Urea FDA Label
12	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
13	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
14	ClinicalTrials.gov (NCT00003021) Bizelesin in Treating Patients With Advanced Cancer. U.S. National Institutes of Health.
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16	p63 is a key regulator of iRHOM2 signalling in the keratinocyte stress response.Nat Commun. 2018 Mar 9;9(1):1021.
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18	Dendritic cell subsets and immunological milieu in inflammatory human papilloma virus-related skin lesions.J Dermatol Sci. 2011 Sep;63(3):173-83. doi: 10.1016/j.jdermsci.2011.05.006. Epub 2011 Jun 6.
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21	Update on protease-activated receptor 2 in cutaneous barrier, differentiation, tumorigenesis and pigmentation, and its role in related dermatologic diseases.Exp Dermatol. 2019 Aug;28(8):877-885. doi: 10.1111/exd.13936. Epub 2019 May 15.
22	Mutations in Cx30 that are linked to skin disease and non-syndromic hearing loss exhibit several distinct cellular pathologies.J Cell Sci. 2014 Apr 15;127(Pt 8):1751-64. doi: 10.1242/jcs.138230. Epub 2014 Feb 12.
23	Granzyme B in skin inflammation and disease.Matrix Biol. 2019 Jan;75-76:126-140. doi: 10.1016/j.matbio.2017.12.005. Epub 2017 Dec 14.
24	Signaling via the IL-20 receptor inhibits cutaneous production of IL-1 and IL-17A to promote infection with methicillin-resistant Staphylococcus aureus.Nat Immunol. 2013 Aug;14(8):804-11. doi: 10.1038/ni.2637. Epub 2013 Jun 23.
25	Photoaging and skin cancer: Is the inflammasome the missing link?.Mech Ageing Dev. 2018 Jun;172:131-137. doi: 10.1016/j.mad.2018.03.003. Epub 2018 Mar 12.
26	Oleic acid as the active agent and lipid matrix in cilomilast-loaded nanocarriers to assist PDE4 inhibition of activated neutrophils for mitigating psoriasis-like lesions.Acta Biomater. 2019 May;90:350-361. doi: 10.1016/j.actbio.2019.04.002. Epub 2019 Apr 3.
27	Development of a liver-targeted stearoyl-CoA desaturase (SCD) inhibitor (MK-8245) to establish a therapeutic window for the treatment of diabetes and dyslipidemia. J Med Chem. 2011 Jul 28;54(14):5082-96.
28	A three-dimensional model of the human transglutaminase 1: insights into the understanding of lamellar ichthyosis. J Mol Model. 2007 Jan;13(1):233-46.
29	Pharmacological Inhibition of the Temperature-Sensitive and Ca(2+)-Permeable Transient Receptor Potential Vanilloid TRPV3 Channel by Natural Forsythoside B Attenuates Pruritus and Cytotoxicity of Keratinocytes.J Pharmacol Exp Ther. 2019 Jan;368(1):21-31. doi: 10.1124/jpet.118.254045. Epub 2018 Oct 30.
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