General Information of Disease (ID: DISANYTW)

Disease Name Invasive breast carcinoma
Synonyms
BRCA; invasive mammary carcinoma; invasive breast carcinoma; infiltrating carcinoma of breast; infiltrating breast carcinoma; infiltrating carcinoma of the breast; invasive breast cancer; invasive carcinoma of breast; invasive carcinoma of the breast; infiltrating breast cancer
Definition
A carcinoma that infiltrates the breast parenchyma. The vast majority are adenocarcinomas arising from the terminal ductal lobular unit (TDLU). Often, the invasive adenocarcinoma co-exists with ductal or lobular carcinoma in situ. It is the most common carcinoma affecting women.
Disease Hierarchy
:
DIS2UE88: Breast carcinoma
DISANYTW: Invasive breast carcinoma
Disease Identifiers
MONDO ID
MONDO_0006256
UMLS CUI
C0853879
MedGen ID
163435
SNOMED CT ID
713609000

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 51 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
BCL6 TTC9YX5 Limited Altered Expression [1]
BRCA2 TTUARD6 Limited Genetic Variation [2]
CD1A TTBGTFN Limited Altered Expression [3]
CYP2D6 TTVG215 Limited Genetic Variation [4]
EPCAM TTZ8WH4 Limited Biomarker [5]
EPHB6 TTZEMUY Limited Altered Expression [6]
FDXR TT3W4IX Limited Altered Expression [7]
GGH TTZJRL0 Limited Biomarker [8]
IL13RA2 TTMPZ7V Limited Altered Expression [9]
PPM1D TTENJAB Limited Altered Expression [10]
PYGM TTZHY6R Limited Genetic Variation [11]
REL TT1ZCTH Limited Biomarker [12]
TMPRSS2 TT1GM2Z Limited Altered Expression [13]
CCNA2 TTAMQ62 Disputed Biomarker [14]
CDH5 TTXLCFO Disputed Posttranslational Modification [15]
FGFBP1 TTV1YFT Disputed Biomarker [16]
GNRH1 TT0ID4A Disputed Biomarker [17]
MAP3K11 TTETX6Q Disputed Biomarker [18]
PBRM1 TTH8ZRL Disputed Altered Expression [19]
PLD2 TTRLMKF Disputed Altered Expression [20]
CA9 TT2LVK8 moderate Altered Expression [21]
FKBP1A TTMW94E moderate Altered Expression [22]
FST TTDNM9W moderate Altered Expression [23]
KRT19 TT3JF9E moderate Altered Expression [24]
LNPEP TTY2KP7 moderate Biomarker [25]
MAGEA3 TTWSKHD moderate Biomarker [26]
MAP3K21 TTSW9YL moderate Altered Expression [27]
RXRG TTH029C moderate Biomarker [28]
SNCG TT5TQNZ moderate Altered Expression [29]
CCN1 TTPK79J Strong Biomarker [30]
CTSA TT5NILS Strong Altered Expression [31]
CYP19A1 TTSZLWK Strong Biomarker [32]
F2RL2 TTVSEBF Strong Biomarker [33]
FSHR TTZFDBT Strong Altered Expression [34]
GMNN TT390KA Strong Altered Expression [35]
IL13RA1 TTNEAMG Strong Altered Expression [36]
OLFM4 TTK1CX7 Strong Altered Expression [37]
PTPN14 TTNIR6C Strong Altered Expression [38]
RPS6KA5 TTYXEPL Strong Altered Expression [39]
SEPTIN6 TTAGE7U Strong Biomarker [40]
TOP2A TTCGY2K Strong Altered Expression [41]
TRIM27 TTTO3QN Strong Genetic Variation [42]
BST2 TT90BJT Definitive Altered Expression [43]
FANCF TTNZKFJ Definitive Posttranslational Modification [44]
FOXQ1 TTEJZOL Definitive Altered Expression [45]
KLK6 TTLPF4X Definitive Biomarker [46]
KLRC1 TTC4IMS Definitive Biomarker [47]
MAP2K5 TTV3O87 Definitive Altered Expression [48]
PLOD2 TT8MEUD Definitive Biomarker [49]
PRKCZ TTBSN0L Definitive Biomarker [50]
S1PR2 TTVSMOH Definitive Altered Expression [51]
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⏷ Show the Full List of 51 DTT(s)
This Disease Is Related to 2 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
ABCC11 DTWN7FC Disputed Genetic Variation [52]
ATP2B1 DTJWQ1L Strong Altered Expression [53]
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This Disease Is Related to 3 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
NDUFS3 DE741FI Limited Biomarker [54]
AKR1A1 DED2FW3 moderate Altered Expression [55]
HSD17B7 DEDMWFX Strong Genetic Variation [56]
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This Disease Is Related to 106 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
ANKRD30A OTJXYAE5 Limited Biomarker [57]
ARID3B OTUP9MS4 Limited Altered Expression [58]
BRCA1 OT5BN6VH Limited Genetic Variation [2]
BRMS1 OTV5A6LL Limited Altered Expression [59]
CBX2 OTOQ5WS4 Limited Biomarker [60]
CLDN3 OT71MN9S Limited Altered Expression [61]
FZD1 OTZATHVS Limited Altered Expression [62]
GREB1 OTU6ZA26 Limited Altered Expression [61]
HAS2 OTTD3PAL Limited Altered Expression [63]
HBP1 OTDPGGDV Limited Altered Expression [64]
HRG OTPLUFOG Limited Biomarker [65]
ILRUN OTE8FHQD Limited Biomarker [66]
INTS2 OT2N5TCK Limited Genetic Variation [11]
KANK1 OT2E7A6W Limited Altered Expression [67]
LDHB OT9B1CT3 Limited Altered Expression [61]
MYCBPAP OT3W21WR Limited Biomarker [68]
NCOR1 OT04XNOU Limited Altered Expression [69]
PLCB2 OTPAHDGO Limited Altered Expression [70]
RBM15B OTRJ9DT7 Limited Altered Expression [71]
SMR3B OTL5HNM8 Limited Altered Expression [72]
SNX27 OTVPS7S0 Limited Altered Expression [73]
ADGRE2 OTUYJVYG Disputed Biomarker [74]
BLID OT479VJV Disputed Genetic Variation [75]
CEMIP OTK80FYN Disputed Altered Expression [76]
CHST11 OTNJJ5Q1 Disputed Altered Expression [77]
FABP7 OTRE2H4G Disputed Altered Expression [78]
MB OTYWYL2D Disputed Altered Expression [79]
MTUS1 OTBPALMU Disputed Altered Expression [80]
NOP14 OTKPM0Z5 Disputed Altered Expression [81]
PTPN12 OT5WA666 Disputed Biomarker [82]
QSOX1 OT4ZPK4P Disputed Biomarker [83]
RBM3 OTAJ7R31 Disputed Biomarker [84]
SIM2 OT0QWHK4 Disputed Biomarker [85]
TOMM34 OTH6MITE Disputed Altered Expression [86]
ARF6 OTVV7KJO moderate Biomarker [68]
BAG1 OTRQNIA4 moderate Altered Expression [87]
CAP1 OTYM8A2N moderate Biomarker [25]
CST6 OTZVHJTF moderate Biomarker [88]
CTCF OT8ZB70U moderate Altered Expression [89]
DACH1 OTMKNAGG moderate Altered Expression [45]
HACD1 OTEC7EP7 moderate Biomarker [25]
MAP1LC3B OTUYHB84 moderate Biomarker [90]
MEST OT8Q4U8Y moderate Altered Expression [91]
NCSTN OT5QBTA4 moderate Biomarker [92]
PELP1 OTVXQNOT moderate Biomarker [93]
PI3 OT47MTC3 moderate Altered Expression [94]
PIP OTH719AH moderate Biomarker [95]
PXN OTVMMUOF moderate Posttranslational Modification [96]
SERPINB6 OT7G55IK moderate Biomarker [25]
SH3BP4 OTVIRKW7 moderate Altered Expression [97]
SORBS1 OTWH8762 moderate Biomarker [25]
AFAP1L2 OTJBI0VN Strong Biomarker [98]
ARHGAP18 OTYMJP6H Strong Biomarker [99]
ARHGEF11 OTDOMEH6 Strong Altered Expression [100]
ATP2B2 OT1NPZ9T Strong Altered Expression [53]
ATP2B4 OTMWFDAC Strong Altered Expression [53]
CCL1 OT23NON8 Strong Altered Expression [101]
CHI3L2 OT26R3HQ Strong Altered Expression [102]
CSTA OT1K68KE Strong Biomarker [103]
DGCR8 OT62LXE4 Strong Altered Expression [104]
DLGAP5 OTWCN39U Strong Biomarker [105]
ELP3 OTT5UKSZ Strong Biomarker [106]
GNL3 OTILGYO4 Strong Altered Expression [107]
GPAA1 OTWVRR35 Strong Altered Expression [108]
ITFG1 OTX0PCR3 Strong Biomarker [109]
NUSAP1 OT85HIJ5 Strong Biomarker [105]
PARD3 OTH5BPLO Strong Biomarker [33]
PRPF38B OTQLH551 Strong Altered Expression [110]
RAPH1 OTMQXW7S Strong Altered Expression [111]
RNF126 OTTECSYY Strong Biomarker [112]
RUVBL1 OTWV19L7 Strong Biomarker [109]
SEPTIN2 OT3G33TM Strong Biomarker [40]
SEPTIN7 OTJI08YX Strong Biomarker [40]
SMARCAD1 OT90AZTX Strong Biomarker [113]
SPAM1 OTMPOB4E Strong Altered Expression [114]
TBX3 OTM64N7K Strong Biomarker [115]
THBS2 OTXET551 Strong Biomarker [116]
THRSP OTKYE01L Strong Altered Expression [117]
TRIM62 OT15YO6N Strong Genetic Variation [118]
ARFGEF1 OTPAU0L4 Definitive Biomarker [119]
BCS1L OT5PY5CY Definitive Biomarker [120]
BHLHE22 OTZUQY5L Definitive Altered Expression [121]
CERS6 OTOP4GV1 Definitive Biomarker [51]
CNTN3 OTC1274J Definitive Biomarker [119]
ECT2 OTQDUCT6 Definitive Biomarker [122]
EPS8 OTZ6ES6V Definitive Altered Expression [123]
FERMT2 OTZNPWWX Definitive Biomarker [124]
FEV OTYEC4IR Definitive Biomarker [125]
G0S2 OT8FL49L Definitive Biomarker [126]
GRB7 OTF8Y9XY Definitive Altered Expression [127]
HERC3 OTWMKYD9 Definitive Altered Expression [128]
KRT14 OTUVZ1DW Definitive Biomarker [129]
MAP2K4 OTZPZX11 Definitive Genetic Variation [130]
MARCHF3 OT89V4N5 Definitive Biomarker [131]
NRF1 OTOXWNV8 Definitive Biomarker [132]
PALB2 OT6DNDBG Definitive Genetic Variation [133]
PRIMPOL OTVK6K9J Definitive Altered Expression [134]
PRKD3 OT987HJI Definitive Biomarker [135]
PUM1 OTTMWP8L Definitive Biomarker [136]
RAP1GAP OTC31ONQ Definitive Altered Expression [137]
S100A7 OTJFVJRF Definitive Altered Expression [138]
SETD1A OTVVWRIC Definitive Altered Expression [139]
SIPA1 OTXY5RXC Definitive Biomarker [140]
SLN OTERIU75 Definitive Biomarker [141]
TM4SF1 OTY0ECQN Definitive Altered Expression [142]
TRIM29 OT2DNESG Definitive Biomarker [143]
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⏷ Show the Full List of 106 DOT(s)

References

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2 Risk of ipsilateral breast tumor recurrence in primary invasive breast cancer following breast-conserving surgery with BRCA1 and BRCA2 mutation in China.Breast Cancer Res Treat. 2019 Jun;175(3):749-754. doi: 10.1007/s10549-019-05199-8. Epub 2019 Mar 20.
3 In breast carcinoma tissue, immature dendritic cells reside within the tumor, whereas mature dendritic cells are located in peritumoral areas.J Exp Med. 1999 Nov 15;190(10):1417-26. doi: 10.1084/jem.190.10.1417.
4 Comprehensive CYP2D6 genotype and adherence affect outcome in breast cancer patients treated with tamoxifen monotherapy.Breast Cancer Res Treat. 2011 Jan;125(1):279-87. doi: 10.1007/s10549-010-1139-x. Epub 2010 Sep 1.
5 Phenotype-dependent effects of EpCAM expression on growth and invasion of human breast cancer cell lines.BMC Cancer. 2012 Oct 30;12:501. doi: 10.1186/1471-2407-12-501.
6 Tyrosine kinase-deficient EphB6 receptor-dependent alterations in proteomic profiles of invasive breast carcinoma cells as determined by difference gel electrophoresis.Cancer Genomics Proteomics. 2010 Sep-Oct;7(5):253-60.
7 Proteomic phenotyping: metastatic and invasive breast cancer.Cancer Lett. 2004 Jul 16;210(2):245-53. doi: 10.1016/j.canlet.2004.01.019.
8 High levels of -glutamyl hydrolase (GGH) are associated with poor prognosis and unfavorable clinical outcomes in invasive breast cancer.BMC Cancer. 2013 Feb 1;13:47. doi: 10.1186/1471-2407-13-47.
9 Interleukin-13 receptor alpha 2 expression in tumor cells is associated with reduced disease-free survival in patients with luminal subtype invasive breast cancer.Tumour Biol. 2018 Jun;40(6):1010428318783657. doi: 10.1177/1010428318783657.
10 Clinical Significance of the Wild Type p53-Induced Phosphatase 1 Expression in Invasive Breast Cancer.Clin Breast Cancer. 2018 Aug;18(4):e643-e650. doi: 10.1016/j.clbc.2017.11.008. Epub 2017 Nov 21.
11 Identical allelic loss on chromosome 11q13 in microdissected in situ and invasive human breast cancer.Cancer Res. 1995 Feb 1;55(3):467-71.
12 PKCtheta promotes c-Rel-driven mammary tumorigenesis in mice and humans by repressing estrogen receptor alpha synthesis.J Clin Invest. 2007 Dec;117(12):4009-21. doi: 10.1172/JCI32424.
13 ERG induces a mesenchymal-like state associated with chemoresistance in leukemia cells.Oncotarget. 2014 Jan 30;5(2):351-62. doi: 10.18632/oncotarget.1449.
14 Prediction of recurrence risk in early breast cancer using human epidermal growth factor 2 and cyclin A2.Chin Med J (Engl). 2010 Feb 20;123(4):431-7.
15 Integrin 21 mediates tyrosine phosphorylation of vascular endothelial cadherin induced by invasive breast cancer cells.J Biol Chem. 2012 Sep 21;287(39):32981-92. doi: 10.1074/jbc.M112.395905. Epub 2012 Jul 25.
16 KLF5 promotes breast cell survival partially through fibroblast growth factor-binding protein 1-pERK-mediated dual specificity MKP-1 protein phosphorylation and stabilization.J Biol Chem. 2009 Jun 19;284(25):16791-16798. doi: 10.1074/jbc.M808919200. Epub 2009 May 1.
17 Genetic polymorphisms of the GNRH1 and GNRHR genes and risk of breast cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3).BMC Cancer. 2009 Jul 29;9:257. doi: 10.1186/1471-2407-9-257.
18 MLK3 is critical for breast cancer cell migration and promotes a malignant phenotype in mammary epithelial cells.Oncogene. 2010 Aug 5;29(31):4399-411. doi: 10.1038/onc.2010.198. Epub 2010 May 31.
19 Identifying the molecular signature of the interstitial deletion 7q subgroup of uterine leiomyomata using a paired analysis.Genes Chromosomes Cancer. 2009 Oct;48(10):865-85. doi: 10.1002/gcc.20692.
20 Phospholipase D (PLD) drives cell invasion, tumor growth and metastasis in a human breast cancer xenograph model.Oncogene. 2013 Dec 5;32(49):5551-62. doi: 10.1038/onc.2013.207. Epub 2013 Jun 10.
21 HIF-1 overexpression in ductal carcinoma in situ of the breast in BRCA1 and BRCA2 mutation carriers.PLoS One. 2013;8(2):e56055. doi: 10.1371/journal.pone.0056055. Epub 2013 Feb 8.
22 FKBP12 is a predictive biomarker for efficacy of anthracycline-based chemotherapy in breast cancer.Cancer Chemother Pharmacol. 2019 Oct;84(4):861-872. doi: 10.1007/s00280-019-03923-1. Epub 2019 Aug 19.
23 Follistatin Expression in Human Invasive Breast Tumors: Pathologic and Clinical Associations.Appl Immunohistochem Mol Morphol. 2018 Feb;26(2):108-112. doi: 10.1097/PAI.0000000000000385.
24 Total tumor load assessed by one-step nucleic acid amplification assay as an intraoperative predictor for non-sentinel lymph node metastasis in breast cancer.Breast. 2017 Apr;32:33-36. doi: 10.1016/j.breast.2016.12.011. Epub 2016 Dec 25.
25 Assessment of dual-probe Her-2 fluorescent in situ hybridization in breast cancer by the 2013 ASCO/CAP guidelines produces more equivocal results than that by the 2007 ASCO/CAP guidelines.Breast Cancer Res Treat. 2016 Aug;159(1):31-9. doi: 10.1007/s10549-016-3917-6. Epub 2016 Jul 25.
26 Does Tumor Size Predict Response to Neoadjuvant Chemotherapy in the Modern Era of Biologically Driven Treatment? A Nationwide Study of US Breast Cancer Patients.Clin Breast Cancer. 2019 Dec;19(6):e741-e747. doi: 10.1016/j.clbc.2019.05.014. Epub 2019 Jun 6.
27 Upregulation of MLK4 promotes migratory and invasive potential of breast cancer cells.Oncogene. 2019 Apr;38(15):2860-2875. doi: 10.1038/s41388-018-0618-0. Epub 2018 Dec 14.
28 Retinoid X receptor gamma (RXRG) is an independent prognostic biomarker in ER-positive invasive breast cancer.Br J Cancer. 2019 Oct;121(9):776-785. doi: 10.1038/s41416-019-0589-0. Epub 2019 Sep 27.
29 Identification, localization and characterization of the human gamma-synuclein gene.Hum Genet. 1998 Jul;103(1):106-12. doi: 10.1007/s004390050792.
30 Inhibition of CYR61-S100A4 Axis Limits Breast Cancer Invasion.Front Oncol. 2019 Oct 23;9:1074. doi: 10.3389/fonc.2019.01074. eCollection 2019.
31 The prognostic significance of lysosomal protective protein (cathepsin A) in breast ductal carcinoma insitu.Histopathology. 2019 Jun;74(7):1025-1035. doi: 10.1111/his.13835. Epub 2019 Apr 14.
32 Verifiable fully outsourced attribute-based signcryption system for IoT eHealth big data in cloud computing.Math Biosci Eng. 2019 Apr 22;16(5):3561-3594. doi: 10.3934/mbe.2019178.
33 Loss of the Par3 polarity protein promotes breast tumorigenesis and metastasis.Cancer Cell. 2012 Nov 13;22(5):601-14. doi: 10.1016/j.ccr.2012.10.003.
34 Endothelial follicle-stimulating hormone receptor expression in invasive breast cancer and vascular remodeling at tumor periphery.J Exp Clin Cancer Res. 2015 Feb 5;34(1):12. doi: 10.1186/s13046-015-0128-7.
35 Geminin predicts adverse clinical outcome in breast cancer by reflecting cell-cycle progression.J Pathol. 2004 Oct;204(2):121-30. doi: 10.1002/path.1625.
36 Elevated Interleukin-13 Receptor Alpha 1 Expression in Tumor Cells Is Associated with Poor Prognosis in Patients with Invasive Breast Cancer.Ann Surg Oncol. 2017 Nov;24(12):3780-3787. doi: 10.1245/s10434-017-5907-2. Epub 2017 Jun 20.
37 OLFM4 Expression in Ductal Carcinoma In Situ and in Invasive Breast Cancer Cohorts by a SWATH-Based Proteomic Approach.Proteomics. 2019 Nov;19(21-22):e1800446. doi: 10.1002/pmic.201800446. Epub 2019 Aug 8.
38 The tyrosine phosphatase PTPN14 (Pez) inhibits metastasis by altering protein trafficking.Sci Signal. 2015 Feb 17;8(364):ra18. doi: 10.1126/scisignal.2005547.
39 High nuclear MSK1 is associated with longer survival in breast cancer patients.J Cancer Res Clin Oncol. 2018 Mar;144(3):509-517. doi: 10.1007/s00432-018-2579-7. Epub 2018 Jan 11.
40 The requirement of SEPT2 and SEPT7 for migration and invasion in human breast cancer via MEK/ERK activation.Oncotarget. 2016 Sep 20;7(38):61587-61600. doi: 10.18632/oncotarget.11402.
41 Clinical significance of topoisomerase 2A expression and gene change in operable invasive breast cancer.Tumour Biol. 2015 Sep;36(9):6833-8. doi: 10.1007/s13277-015-3390-6. Epub 2015 Apr 7.
42 RET finger protein expression in invasive breast carcinoma: relationship between RFP and ErbB2 expression.Pathol Res Pract. 2009;205(6):403-8. doi: 10.1016/j.prp.2008.12.014. Epub 2009 Feb 20.
43 BST-2 promotes survival in circulation and pulmonary metastatic seeding of breast cancer cells.Sci Rep. 2018 Dec 4;8(1):17608. doi: 10.1038/s41598-018-35710-y.
44 Low incidence of methylation of the promoter region of the FANCF gene in Japanese primary breast cancer.Breast Cancer. 2011 Apr;18(2):120-3. doi: 10.1007/s12282-009-0175-z. Epub 2009 Oct 8.
45 Forkhead Box Q1 Is a Novel Target of Breast Cancer Stem Cell Inhibition by Diallyl Trisulfide.J Biol Chem. 2016 Jun 24;291(26):13495-508. doi: 10.1074/jbc.M116.715219. Epub 2016 Apr 29.
46 An integrated cell line-based discovery strategy identified follistatin and kallikrein 6 as serum biomarker candidates of breast carcinoma.J Proteomics. 2016 Jun 16;142:114-21. doi: 10.1016/j.jprot.2016.04.050. Epub 2016 May 7.
47 CD16(+)NKG2A(high) Natural Killer Cells Infiltrate Breast Cancer-Draining Lymph Nodes.Cancer Immunol Res. 2019 Feb;7(2):208-218. doi: 10.1158/2326-6066.CIR-18-0085. Epub 2018 Dec 4.
48 Upregulation of MEK5 by Stat3 promotes breast cancer cell invasion and metastasis.Oncol Rep. 2017 Jan;37(1):83-90. doi: 10.3892/or.2016.5256. Epub 2016 Nov 18.
49 Tumor-secreted PAI-1 promotes breast cancer metastasis via the induction of adipocyte-derived collagen remodeling.Cell Commun Signal. 2019 Jun 6;17(1):58. doi: 10.1186/s12964-019-0373-z.
50 PKC Promotes Breast Cancer Invasion by Regulating Expression of E-cadherin and Zonula Occludens-1 (ZO-1) via NFB-p65.Sci Rep. 2015 Jul 28;5:12520. doi: 10.1038/srep12520.
51 C16ceramide and sphingosine1phosphate/S1PR2 have opposite effects on cell growth through mTOR signaling pathway regulation.Oncol Rep. 2018 Nov;40(5):2977-2987. doi: 10.3892/or.2018.6689. Epub 2018 Sep 7.
52 Association between breast cancer risk and the wild-type allele of human ABC transporter ABCC11.Anticancer Res. 2010 Dec;30(12):5189-94.
53 Expression of calcium pumps is differentially regulated by histone deacetylase inhibitors and estrogen receptor alpha in breast cancer cells.BMC Cancer. 2018 Oct 23;18(1):1029. doi: 10.1186/s12885-018-4945-x.
54 Biomarker signatures of mitochondrial NDUFS3 in invasive breast carcinoma.Biochem Biophys Res Commun. 2011 Sep 9;412(4):590-5. doi: 10.1016/j.bbrc.2011.08.003. Epub 2011 Aug 16.
55 Class I alcohol dehydrogenase is highly expressed in normal human mammary epithelium but not in invasive breast cancer: implications for breast carcinogenesis.Cancer Res. 2003 Jun 15;63(12):3092-100.
56 High expression of steroid sulfatase mRNA predicts poor prognosis in patients with estrogen receptor-positive breast cancer.Clin Cancer Res. 2003 Jun;9(6):2288-93.
57 Preferential nuclear and cytoplasmic NY-BR-1 protein expression in primary breast cancer and lymph node metastases.Clin Cancer Res. 2006 May 1;12(9):2745-51. doi: 10.1158/1078-0432.CCR-05-2192.
58 ARID3B expression in primary breast cancers and breast cancer-derived cell lines.Cell Oncol (Dordr). 2014 Aug;37(4):289-96. doi: 10.1007/s13402-014-0185-5. Epub 2014 Aug 14.
59 Reduced expression of the breast cancer metastasis suppressor 1 mRNA is correlated with poor progress in breast cancer.Clin Cancer Res. 2006 Nov 1;12(21):6410-4. doi: 10.1158/1078-0432.CCR-06-1347.
60 A novel approach to modelling transcriptional heterogeneity identifies the oncogene candidate CBX2 in invasive breast carcinoma.Br J Cancer. 2019 Apr;120(7):746-753. doi: 10.1038/s41416-019-0387-8. Epub 2019 Mar 1.
61 Gene expression signatures and biomarkers of noninvasive and invasive breast cancer cells: comprehensive profiles by representational difference analysis, microarrays and proteomics.Oncogene. 2006 Apr 13;25(16):2328-38. doi: 10.1038/sj.onc.1209265.
62 Expression of Wnt genes and frizzled 1 and 2 receptors in normal breast epithelium and infiltrating breast carcinoma.Int J Oncol. 2004 Nov;25(5):1337-42.
63 Antisense-mediated suppression of hyaluronan synthase 2 inhibits the tumorigenesis and progression of breast cancer.Cancer Res. 2005 Jul 15;65(14):6139-50. doi: 10.1158/0008-5472.CAN-04-1622.
64 Alterations of the HBP1 transcriptional repressor are associated with invasive breast cancer.Cancer Res. 2007 Jul 1;67(13):6136-45. doi: 10.1158/0008-5472.CAN-07-0567.
65 Co-expression of ErbB-family members in human breast cancer: Her-2/neu is the preferred dimerization candidate in nodal-positive tumors.Breast Cancer Res Treat. 2003 Aug;80(3):353-61. doi: 10.1023/A:1024929522376.
66 A novel biomarker C6orf106 promotes the malignant progression of breast cancer.Tumour Biol. 2015 Sep;36(10):7881-9. doi: 10.1007/s13277-015-3500-5. Epub 2015 May 8.
67 Prognostic significance of KN motif and ankyrin repeat domains 1 (KANK1) in invasive breast cancer.Breast Cancer Res Treat. 2020 Jan;179(2):349-357. doi: 10.1007/s10549-019-05466-8. Epub 2019 Nov 2.
68 Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis.Proc Natl Acad Sci U S A. 2006 May 2;103(18):7036-41. doi: 10.1073/pnas.0509166103. Epub 2006 Apr 24.
69 NCOR1 mRNA is an independent prognostic factor for breast cancer.Cancer Lett. 2006 Jun 8;237(1):123-9. doi: 10.1016/j.canlet.2005.05.046. Epub 2005 Jul 12.
70 Ectopic expression of PLC-2 in non-invasive breast tumor cells plays a protective role against malignant progression and is correlated with the deregulation of miR-146a.Mol Carcinog. 2019 May;58(5):708-721. doi: 10.1002/mc.22964. Epub 2019 Jan 16.
71 BAP1 expression is prognostic in breast and uveal melanoma but not colon cancer and is highly positively correlated with RBM15B and USP19.PLoS One. 2019 Feb 4;14(2):e0211507. doi: 10.1371/journal.pone.0211507. eCollection 2019.
72 Expression and prognostic impact of the protein tyrosine phosphatases PRL-1, PRL-2, and PRL-3 in breast cancer.Br J Cancer. 2006 Aug 7;95(3):347-54. doi: 10.1038/sj.bjc.6603261. Epub 2006 Jul 11.
73 SNX27-retromer assembly recycles MT1-MMP to invadopodia and promotes breast cancer metastasis.J Cell Biol. 2020 Jan 6;219(1):e201812098. doi: 10.1083/jcb.201812098.
74 Leukocyte adhesion-GPCR EMR2 is aberrantly expressed in human breast carcinomas and is associated with patient survival.Oncol Rep. 2011 Mar;25(3):619-27. doi: 10.3892/or.2010.1117. Epub 2010 Dec 21.
75 Frequent loss of the BLID gene in early-onset breast cancer.Cytogenet Genome Res. 2011;135(1):19-24. doi: 10.1159/000330265. Epub 2011 Aug 12.
76 Unraveling the role of KIAA1199, a novel endoplasmic reticulum protein, in cancer cell migration.J Natl Cancer Inst. 2013 Sep 18;105(18):1402-16. doi: 10.1093/jnci/djt224. Epub 2013 Aug 29.
77 Chondroitin sulfates play a major role in breast cancer metastasis: a role for CSPG4 and CHST11 gene expression in forming surface P-selectin ligands in aggressive breast cancer cells.Breast Cancer Res. 2011 Jun 9;13(3):R58. doi: 10.1186/bcr2895.
78 The proteins FABP7 and OATP2 are associated with the basal phenotype and patient outcome in human breast cancer.Breast Cancer Res Treat. 2010 May;121(1):41-51. doi: 10.1007/s10549-009-0450-x. Epub 2009 Jul 10.
79 Endogenous myoglobin in human breast cancer is a hallmark of luminal cancer phenotype.Br J Cancer. 2010 Jun 8;102(12):1736-45. doi: 10.1038/sj.bjc.6605702.
80 8p22 MTUS1 gene product ATIP3 is a novel anti-mitotic protein underexpressed in invasive breast carcinoma of poor prognosis.PLoS One. 2009 Oct 1;4(10):e7239. doi: 10.1371/journal.pone.0007239.
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