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A phase I trial of intratumoral administration of recombinant oncolytic adenovirus overexpressing HSP70 in advanced solid tumor patients. Gene Ther. 2009 Mar;16(3):376-82.
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ClinicalTrials.gov (NCT03696030) HER2-CAR T Cells in Treating Participants With Brain or Leptomeningeal Metastases
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ClinicalTrials.gov (NCT02414269) Malignant Pleural Disease Treated With Autologous T Cells Genetically Engineered to Target the Cancer-Cell Surface Antigen Mesothelin
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The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
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Depletion of Lipid Efflux Pump ABCG1 Triggers the Intracellular Accumulation of Extracellular Vesicles and Reduces Aggregation and Tumorigenesis of Metastatic Cancer Cells.Front Oncol. 2018 Oct 10;8:376. doi: 10.3389/fonc.2018.00376. eCollection 2018.
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Adamalysines as Biomarkers and a Potential Target of Therapy in Colorectal Cancer Patients: Preliminary Results.Dis Markers. 2019 Sep 2;2019:5035234. doi: 10.1155/2019/5035234. eCollection 2019.
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ADAMTS5 acts as a tumor suppressor by inhibiting migration, invasion and angiogenesis in human gastric cancer.Gastric Cancer. 2019 Mar;22(2):287-301. doi: 10.1007/s10120-018-0866-2. Epub 2018 Aug 13.
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Immunostimulating and cancer-reductive experimental therapy with the oxazaphosphorine cytostatic SUM-IAP.Anticancer Drugs. 2018 Jun;29(5):411-415. doi: 10.1097/CAD.0000000000000608.
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Asparaginase-like protein 1 is an independent prognostic marker in primary endometrial cancer, and is frequently lost in metastatic lesions.Gynecol Oncol. 2018 Jan;148(1):197-203. doi: 10.1016/j.ygyno.2017.10.025. Epub 2017 Oct 31.
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An analysis of a multiple biomarker panel to better predict prostate cancer metastasis after radical prostatectomy.Int J Cancer. 2019 Mar 1;144(5):1151-1159. doi: 10.1002/ijc.31906. Epub 2018 Dec 4.
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Quantitative phosphoproteomic analysis reveals system-wide signaling pathways downstream of SDF-1/CXCR4 in breast cancer stem cells.Proc Natl Acad Sci U S A. 2014 May 27;111(21):E2182-90. doi: 10.1073/pnas.1404943111. Epub 2014 Apr 29.
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The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer.Mol Cell. 2018 Jan 4;69(1):87-99.e7. doi: 10.1016/j.molcel.2017.11.025. Epub 2017 Dec 14.
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CIC-DUX4 oncoprotein drives sarcoma metastasis and tumorigenesis via distinct regulatory programs.J Clin Invest. 2019 Jul 22;129(8):3401-3406. doi: 10.1172/JCI126366. eCollection 2019 Jul 22.
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CCR4 is a determinant of melanoma brain metastasis.Oncotarget. 2017 May 9;8(19):31079-31091. doi: 10.18632/oncotarget.16076.
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CCR5 status and metastatic progression in colorectal cancer.Oncoimmunology. 2019 Jul 13;8(9):e1626193. doi: 10.1080/2162402X.2019.1626193. eCollection 2019.
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Selective targeting of collagen IV in the cancer cell microenvironment reduces tumor burden.Oncotarget. 2018 Jan 19;9(13):11020-11045. doi: 10.18632/oncotarget.24280. eCollection 2018 Feb 16.
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DNAM-1 and the TIGIT/PVRIG/TACTILE Axis: Novel Immune Checkpoints for Natural Killer Cell-Based Cancer Immunotherapy.Cancers (Basel). 2019 Jun 23;11(6):877. doi: 10.3390/cancers11060877.
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CDC20 associated with cancer metastasis and novel mushroomderived CDC20 inhibitors with antimetastatic activity.Int J Oncol. 2019 Jun;54(6):2250-2256. doi: 10.3892/ijo.2019.4791. Epub 2019 Apr 18.
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Pan-Cancer Analysis of the Mediator Complex Transcriptome Identifies CDK19 and CDK8 as Therapeutic Targets in Advanced Prostate Cancer.Clin Cancer Res. 2017 Apr 1;23(7):1829-1840. doi: 10.1158/1078-0432.CCR-16-0094. Epub 2016 Sep 27.
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Carboxypeptidase E-N promotes migration, invasiveness, and epithelial-mesenchymal transition of human osteosarcoma cells via the Wnt--catenin pathway.Biochem Cell Biol. 2019 Aug;97(4):446-453. doi: 10.1139/bcb-2018-0236. Epub 2018 Dec 3.
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Balanced Steady-State Free Precession Sequence (CISS/FIESTA/3D Driven Equilibrium Radiofrequency Reset Pulse) Increases the Diagnostic Yield for Spinal Drop Metastases in Children with Brain Tumors.AJNR Am J Neuroradiol. 2018 Jul;39(7):1355-1361. doi: 10.3174/ajnr.A5645. Epub 2018 May 17.
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Sex-dependent correlation between survival and expression of genes related to the circadian oscillator in patients with colorectal cancer.Chronobiol Int. 2018 Sep;35(10):1423-1434. doi: 10.1080/07420528.2018.1488722. Epub 2018 Jun 28.
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Immune targets and neoantigens for cancer immunotherapy and precision medicine.Cell Res. 2017 Jan;27(1):11-37. doi: 10.1038/cr.2016.155. Epub 2016 Dec 27.
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Targeting CTCFL/BORIS for the immunotherapy of cancer. Cancer Immunol Immunother. 2018 Dec;67(12):1955-1965.
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Gut microbiota-stimulated cathepsin K secretion mediates TLR4-dependent M2 macrophage polarization and promotes tumor metastasis in colorectal cancer.Cell Death Differ. 2019 Nov;26(11):2447-2463. doi: 10.1038/s41418-019-0312-y. Epub 2019 Mar 8.
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Prognostic role of XTP1/DEPDC1B and SDP35/DEPDC1A in high grade soft-tissue sarcomas.Histol Histopathol. 2018 Jun;33(6):597-608. doi: 10.14670/HH-11-959. Epub 2018 Jan 3.
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MDA-7/IL-24 regulates the miRNA processing enzyme DICER through downregulation of MITF.Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5687-5692. doi: 10.1073/pnas.1819869116. Epub 2019 Mar 6.
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Tumor-secreted dickkopf2 accelerates aerobic glycolysis and promotes angiogenesis in colorectal cancer.Theranostics. 2019 Jan 30;9(4):1001-1014. doi: 10.7150/thno.30056. eCollection 2019.
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Eukaryotic elongation factor 2 kinase upregulates the expression of proteins implicated in cell migration and cancer cell metastasis.Int J Cancer. 2018 May 1;142(9):1865-1877. doi: 10.1002/ijc.31210. Epub 2017 Dec 27.
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Factor XIIIA-expressing inflammatory monocytes promote lung squamous cancer through fibrin cross-linking.Nat Commun. 2018 May 18;9(1):1988. doi: 10.1038/s41467-018-04355-w.
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Androgen and Estrogen Receptor Imaging in Metastatic Breast Cancer Patients as a Surrogate for Tissue Biopsies.J Nucl Med. 2017 Dec;58(12):1906-1912. doi: 10.2967/jnumed.117.193649. Epub 2017 Sep 14.
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Use of Porphysomes to detect primary tumour, lymph node metastases, intra-abdominal metastases and as a tool for image-guided lymphadenectomy: proof of concept in endometrial cancer.Theranostics. 2019 Apr 13;9(9):2727-2738. doi: 10.7150/thno.31225. eCollection 2019.
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Overexpression of FNDC1 in Gastric Cancer and its Prognostic Significance.J Cancer. 2018 Nov 13;9(24):4586-4595. doi: 10.7150/jca.27672. eCollection 2018.
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Insulinoma-associated protein 1 expression in primary and metastatic neuroendocrine neoplasms of the gastrointestinal and pancreaticobiliary tracts.Histopathology. 2019 Oct;75(4):568-577. doi: 10.1111/his.13899. Epub 2019 Jul 29.
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Cytoplasmic HAX1 Is an Independent Risk Factor for Breast Cancer Metastasis.J Oncol. 2019 Apr 10;2019:6375025. doi: 10.1155/2019/6375025. eCollection 2019.
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The homeostasis-maintaining metabolites from bacterial stress response to bacteriophage infection suppress tumor metastasis.Oncogene. 2018 Oct;37(43):5766-5779. doi: 10.1038/s41388-018-0376-z. Epub 2018 Jun 20.
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TGF-1 induces epigenetic silence of TIP30 to promote tumor metastasis in esophageal carcinoma.Oncotarget. 2015 Feb 10;6(4):2120-33. doi: 10.18632/oncotarget.2940.
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5-hydroxytryptamine receptor (5-HT1DR) promotes colorectal cancer metastasis by regulating Axin1/-catenin/MMP-7 signaling pathway.Oncotarget. 2015 Sep 22;6(28):25975-87. doi: 10.18632/oncotarget.4543.
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Antitumor Activity of BRAF Inhibitor and IFN Combination in BRAF-Mutant Melanoma.J Natl Cancer Inst. 2016 Feb 5;108(7):djv435. doi: 10.1093/jnci/djv435. Print 2016 Jul.
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Tumor-recruited M2 macrophages promote gastric and breast cancer metastasis via M2 macrophage-secreted CHI3L1 protein.J Hematol Oncol. 2017 Feb 1;10(1):36. doi: 10.1186/s13045-017-0408-0.
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Development of a novel class of interleukin-2 immunotherapies for metastatic cancer.Swiss Med Wkly. 2019 Jan 23;149:w14697. doi: 10.4414/smw.2019.14697. eCollection 2019 Jan 14.
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Interleukin-7 Contributes to the Invasiveness of Prostate Cancer Cells by Promoting Epithelial-Mesenchymal Transition.Sci Rep. 2019 May 6;9(1):6917. doi: 10.1038/s41598-019-43294-4.
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ICAM3 mediates tumor metastasis via a LFA-1-ICAM3-ERM dependent manner.Biochim Biophys Acta Mol Basis Dis. 2018 Aug;1864(8):2566-2578. doi: 10.1016/j.bbadis.2018.05.002. Epub 2018 May 3.
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Collective cell migration and metastases induced by an epithelial-to-mesenchymal transition in Drosophila intestinal tumors.Nat Commun. 2019 May 24;10(1):2311. doi: 10.1038/s41467-019-10269-y.
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Function and regulation of LAG3 on CD4(+)CD25(-) T cells in non-small cell lung cancer.Exp Cell Res. 2017 Nov 15;360(2):358-364. doi: 10.1016/j.yexcr.2017.09.026. Epub 2017 Sep 19.
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LAMP1 Overexpression Predicts for Poor Prognosis in Diffuse Large B-cell Lymphoma.Clin Lymphoma Myeloma Leuk. 2018 Nov;18(11):749-754. doi: 10.1016/j.clml.2018.07.288. Epub 2018 Aug 3.
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LAPTM4B Predicts Axillary Lymph Node Metastasis in Breast Cancer and Promotes Breast Cancer Cell Aggressiveness in Vitro.Cell Physiol Biochem. 2017;41(3):1072-1082. doi: 10.1159/000464115. Epub 2017 Feb 27.
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Asparaginyl endopeptidase induces endothelial permeability and tumor metastasis via downregulating zonula occludens protein ZO-1.Biochim Biophys Acta Mol Basis Dis. 2019 Sep 1;1865(9):2267-2275. doi: 10.1016/j.bbadis.2019.05.003. Epub 2019 May 13.
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Leukemia Inhibitory Factor Receptor Suppresses the Metastasis of Clear Cell Renal Cell Carcinoma Through Negative Regulation of the Yes-Associated Protein.DNA Cell Biol. 2018 Aug;37(8):659-669. doi: 10.1089/dna.2017.4102. Epub 2018 Jun 14.
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The stability and oncogenic function of LIN28A are regulated by USP28.Biochim Biophys Acta Mol Basis Dis. 2019 Mar 1;1865(3):599-610. doi: 10.1016/j.bbadis.2018.12.006. Epub 2018 Dec 10.
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Diesel exhaust particle promotes tumor lung metastasis via the induction of BLT1-mediated neutrophilic lung inflammation.Cytokine. 2018 Nov;111:530-540. doi: 10.1016/j.cyto.2018.05.024. Epub 2018 Jun 5.
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Pattern of node metastases in patients treated with radical cystectomy and extended or superextended pelvic lymph node dissection due to bladder cancer.Urol Oncol. 2018 Jun;36(6):307.e9-307.e14. doi: 10.1016/j.urolonc.2018.03.002. Epub 2018 Mar 27.
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MALT1 is a critical mediator of PAR1-driven NF-B activation and metastasis in multiple tumor types.Oncogene. 2019 Dec;38(49):7384-7398. doi: 10.1038/s41388-019-0958-4. Epub 2019 Aug 16.
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Multiple steps of HLA-G in ovarian carcinoma metastasis: alter NK cytotoxicity and induce matrix metalloproteinase-15 (MMP-15) expression.Hum Immunol. 2013 Apr;74(4):439-46. doi: 10.1016/j.humimm.2012.11.021. Epub 2012 Dec 8.
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Enhanced Melanoma-Targeted Therapy by "Fru-Blocked" Phenyboronic Acid-Modified Multiphase Antimetastatic Micellar Nanoparticles.Adv Sci (Weinh). 2018 Jul 13;5(11):1800229. doi: 10.1002/advs.201800229. eCollection 2018 Nov.
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NKp46 Receptor-Mediated Interferon- Production by Natural Killer Cells Increases Fibronectin 1 to Alter Tumor Architecture and Control Metastasis.Immunity. 2018 Jan 16;48(1):107-119.e4. doi: 10.1016/j.immuni.2017.12.007. Epub 2018 Jan 9.
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Calcium signalling links MYC to NUAK1.Oncogene. 2018 Feb 22;37(8):982-992. doi: 10.1038/onc.2017.394. Epub 2017 Nov 6.
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PARP3 inhibitors ME0328 and olaparib potentiate vinorelbine sensitization in breast cancer cell lines.Breast Cancer Res Treat. 2018 Nov;172(1):23-32. doi: 10.1007/s10549-018-4888-6. Epub 2018 Jul 23.
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Targeted genomic landscape of metastases compared to primary tumours in clear cell metastatic renal cell carcinoma.Br J Cancer. 2018 May;118(9):1238-1242. doi: 10.1038/s41416-018-0064-3. Epub 2018 Apr 20.
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Platelet factor 4 is produced by subsets of myeloid cells in premetastatic lung and inhibits tumor metastasis.Oncotarget. 2017 Apr 25;8(17):27725-27739. doi: 10.18632/oncotarget.9486.
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Role of PFKFB3 and CD163 in Oral Squamous Cell Carcinoma Angiogenesis.Curr Med Sci. 2019 Jun;39(3):410-414. doi: 10.1007/s11596-019-2051-1. Epub 2019 Jun 17.
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Pentose conversions support the tumorigenesis of pancreatic cancer distant metastases.Oncogene. 2018 Sep;37(38):5248-5256. doi: 10.1038/s41388-018-0346-5. Epub 2018 May 30.
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A novel cross-talk between CXCR4 and PI4KIII in prostate cancer cells.Oncogene. 2019 Jan;38(3):332-344. doi: 10.1038/s41388-018-0448-0. Epub 2018 Aug 15.
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Phospholipase D messenger RNA expression and clinical role in high-grade serous carcinoma.Hum Pathol. 2017 Apr;62:115-121. doi: 10.1016/j.humpath.2016.12.023. Epub 2017 Jan 11.
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Genomic alterations accompanying tumour evolution in colorectal cancer: tracking the differences between primary tumours and synchronous liver metastases by whole-exome sequencing.BMC Cancer. 2018 Jul 20;18(1):752. doi: 10.1186/s12885-018-4639-4.
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PRKAR2B promotes prostate cancer metastasis by activating Wnt/-catenin and inducing epithelial-mesenchymal transition.J Cell Biochem. 2018 Sep;119(9):7319-7327. doi: 10.1002/jcb.27030. Epub 2018 May 15.
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DNA-PKcs-Mediated Transcriptional Regulation Drives Prostate Cancer Progression and Metastasis.Cancer Cell. 2015 Jul 13;28(1):97-113. doi: 10.1016/j.ccell.2015.06.004.
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PRMT1 Promoted HCC Growth and Metastasis In Vitro and In Vivo via Activating the STAT3 Signalling Pathway.Cell Physiol Biochem. 2018;47(4):1643-1654. doi: 10.1159/000490983. Epub 2018 Jun 23.
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PSIP1/p75 promotes tumorigenicity in breast cancer cells by promoting the transcription of cell cycle genes.Carcinogenesis. 2017 Oct 1;38(10):966-975. doi: 10.1093/carcin/bgx062.
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Immunological differences between primary and metastatic breast cancer.Ann Oncol. 2018 Nov 1;29(11):2232-2239. doi: 10.1093/annonc/mdy399.
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Connexin26 expression is associated with aggressive phenotype in human papillary and follicular thyroid cancers.Cancer Lett. 2008 Apr 18;262(2):248-56. doi: 10.1016/j.canlet.2007.12.008. Epub 2008 Jan 10.
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RIPK2: New Elements in Modulating Inflammatory Breast Cancer Pathogenesis.Cancers (Basel). 2018 Jun 5;10(6):184. doi: 10.3390/cancers10060184.
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ROR2 is a novel prognostic biomarker and a potential therapeutic target in leiomyosarcoma and gastrointestinal stromal tumour.J Pathol. 2012 Jun;227(2):223-33. doi: 10.1002/path.3986. Epub 2012 Feb 17.
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Solute carrier family 12 member 5 promotes tumor invasion/metastasis of bladder urothelial carcinoma by enhancing NF-B/MMP-7 signaling pathway.Cell Death Dis. 2017 Mar 23;8(3):e2691. doi: 10.1038/cddis.2017.118.
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Significance of OCT1 Expression in Acute Myeloid Leukemia.Pathol Oncol Res. 2017 Jul;23(3):665-671. doi: 10.1007/s12253-016-0161-7. Epub 2016 Dec 26.
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Amino acid transporter SLC38A3 promotes metastasis of non-small cell lung cancer cells by activating PDK1.Cancer Lett. 2017 May 1;393:8-15. doi: 10.1016/j.canlet.2017.01.036. Epub 2017 Feb 13.
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Enhanced expression of SRPK2 contributes to aggressive progression and metastasis in prostate cancer.Biomed Pharmacother. 2018 Jun;102:531-538. doi: 10.1016/j.biopha.2018.03.079. Epub 2018 Mar 26.
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Prospects of Targeting the Gastrin Releasing Peptide Receptor and Somatostatin Receptor 2 for Nuclear Imaging and Therapy in Metastatic Breast Cancer.PLoS One. 2017 Jan 20;12(1):e0170536. doi: 10.1371/journal.pone.0170536. eCollection 2017.
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Clinical significance of high expression of stanniocalcin-2 in hepatocellular carcinoma.Biosci Rep. 2019 Apr 26;39(4):BSR20182057. doi: 10.1042/BSR20182057. Print 2019 Apr 30.
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Transcriptional Induction of Periostin by a Sulfatase 2-TGF1-SMAD Signaling Axis Mediates Tumor Angiogenesis in Hepatocellular Carcinoma.Cancer Res. 2017 Feb 1;77(3):632-645. doi: 10.1158/0008-5472.CAN-15-2556. Epub 2016 Nov 21.
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SYK allelic loss and the role of Syk-regulated genes in breast cancer survival.PLoS One. 2014 Feb 11;9(2):e87610. doi: 10.1371/journal.pone.0087610. eCollection 2014.
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Increased trace amine-associated receptor 1 (TAAR1) expression is associated with a positive survival rate in patients with breast cancer.J Cancer Res Clin Oncol. 2017 Sep;143(9):1637-1647. doi: 10.1007/s00432-017-2420-8. Epub 2017 Apr 13.
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CRIPTO and its signaling partner GRP78 drive the metastatic phenotype in human osteotropic prostate cancer.Oncogene. 2017 Aug 17;36(33):4739-4749. doi: 10.1038/onc.2017.87. Epub 2017 Apr 10.
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Expression of immune checkpoint receptors Indoleamine 2,3-dioxygenase and T cell Ig and ITIM domain in metastatic versus nonmetastatic choroidal melanoma.Cancer Med. 2019 Jun;8(6):2784-2792. doi: 10.1002/cam4.2167. Epub 2019 Apr 16.
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Polymorphisms of ESR1, UGT1A1, HCN1, MAP3K1 and CYP2B6 are associated with the prognosis of hormone receptor-positive early breast cancer.Oncotarget. 2017 Mar 28;8(13):20925-20938. doi: 10.18632/oncotarget.14995.
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High expression of WNT7A predicts poor prognosis and promote tumor metastasis in pancreatic ductal adenocarcinoma.Sci Rep. 2018 Oct 25;8(1):15792. doi: 10.1038/s41598-018-34094-3.
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Prostate cancer cell phenotypes based on AGR2 and CD10 expression.Mod Pathol. 2013 Jun;26(6):849-59. doi: 10.1038/modpathol.2012.238. Epub 2013 Jan 25.
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A novel human anti-AXL monoclonal antibody attenuates tumour cell migration.Scand J Immunol. 2019 Aug;90(2):e12777. doi: 10.1111/sji.12777. Epub 2019 Jun 7.
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SERPINE2 promotes esophageal squamous cell carcinoma metastasis by activating BMP4.Cancer Lett. 2020 Jan 28;469:390-398. doi: 10.1016/j.canlet.2019.11.011. Epub 2019 Nov 12.
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Effect of recombinant human endostatin on the expression of c-Myc and bFGF in mouse gastric cancer cells.Genet Mol Res. 2015 May 18;14(2):5258-65. doi: 10.4238/2015.May.18.17.
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FLT1 signaling in metastasis-associated macrophages activates an inflammatory signature that promotes breast cancer metastasis.J Exp Med. 2015 Aug 24;212(9):1433-48. doi: 10.1084/jem.20141555. Epub 2015 Aug 10.
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Aromatase-induced endogenous estrogen promotes tumour metastasis through estrogen receptor-/matrix metalloproteinase 12 axis activation in castration-resistant prostate cancer.Cancer Lett. 2019 Dec 28;467:72-84. doi: 10.1016/j.canlet.2019.09.001. Epub 2019 Sep 6.
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Eukaryotic translation initiation factor 5A2 regulates the migration and invasion of hepatocellular carcinoma cells via pathways involving reactive oxygen species.Oncotarget. 2016 Apr 26;7(17):24348-60. doi: 10.18632/oncotarget.8324.
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Reduction of Circulating Cancer Cells and Metastases in Breast-Cancer Models by a Potent EphA2-Agonistic Peptide-Drug Conjugate.J Med Chem. 2018 Mar 8;61(5):2052-2061. doi: 10.1021/acs.jmedchem.7b01837. Epub 2018 Feb 27.
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Expression profiles of VEGF-A, VEGF-D and VEGFR1 are higher in distant metastases than in matched primary high grade epithelial ovarian cancer.BMC Cancer. 2019 Jun 14;19(1):584. doi: 10.1186/s12885-019-5757-3.
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Extragonadal FSHR Expression and Function-Is It Real?.Front Endocrinol (Lausanne). 2019 Feb 4;10:32. doi: 10.3389/fendo.2019.00032. eCollection 2019.
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Betulinic Acid Suppresses Breast Cancer Metastasis by Targeting GRP78-Mediated Glycolysis and ER Stress Apoptotic Pathway.Oxid Med Cell Longev. 2019 Aug 19;2019:8781690. doi: 10.1155/2019/8781690. eCollection 2019.
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Flavokawain B inhibits growth of human squamous carcinoma cells: Involvement of apoptosis and cell cycle dysregulation in vitro and in vivo.J Nutr Biochem. 2012 Apr;23(4):368-78. doi: 10.1016/j.jnutbio.2011.01.002. Epub 2011 May 2.
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p-AKT overexpression in primary renal cell carcinomas and their metastases.Clin Exp Metastasis. 2010 Dec;27(8):611-7. doi: 10.1007/s10585-010-9351-y. Epub 2010 Sep 16.
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Inhibition of mTORC2/RICTOR Impairs Melanoma Hepatic Metastasis.Neoplasia. 2018 Dec;20(12):1198-1208. doi: 10.1016/j.neo.2018.10.001. Epub 2018 Nov 4.
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Pigment epithelium-derived factor promotes tumor metastasis through an interaction with laminin receptor in hepatocellular carcinomas.Cell Death Dis. 2017 Aug 3;8(8):e2969. doi: 10.1038/cddis.2017.359.
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Expression of T-lymphoma invasion and metastasis factor on the occurrence of oral squamous cell carcinoma.J Biol Regul Homeost Agents. 2017 Apr-Jun;31(2):289-295.
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Leupaxin acts as a mediator in prostate carcinoma progression through deregulation of p120catenin expression.Oncogene. 2009 Nov 12;28(45):3971-82. doi: 10.1038/onc.2009.254. Epub 2009 Aug 24.
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Vitamin D-VDR Signaling Inhibits Wnt/-Catenin-Mediated Melanoma Progression and Promotes Antitumor Immunity.Cancer Res. 2019 Dec 1;79(23):5986-5998. doi: 10.1158/0008-5472.CAN-18-3927. Epub 2019 Nov 5.
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ACR Appropriateness Criteria() Suspected LiverMetastases.J Am Coll Radiol. 2017 May;14(5S):S314-S325. doi: 10.1016/j.jacr.2017.01.037.
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Does the expression of the ACVR2A gene affect the development of colorectal cancer?.Genet Mol Biol. 2019 Jan-Mar;42(1):32-39. doi: 10.1590/1678-4685-GMB-2017-0332. Epub 2019 Mar 11.
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Loss of tumor suppressor miR-126 contributes to the development of hepatitis B virus-related hepatocellular carcinoma metastasis through the upregulation of ADAM9.Tumour Biol. 2017 Jun;39(6):1010428317709128. doi: 10.1177/1010428317709128.
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Testosterone accumulation in prostate cancer cells is enhanced by facilitated diffusion.Prostate. 2019 Sep;79(13):1530-1542. doi: 10.1002/pros.23874. Epub 2019 Aug 2.
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Transcriptional activation of ANO1 promotes gastric cancer progression.Biochem Biophys Res Commun. 2019 Apr 23;512(1):131-136. doi: 10.1016/j.bbrc.2019.03.001. Epub 2019 Mar 12.
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Identification of core genes and outcome in gastric cancer using bioinformatics analysis.Oncotarget. 2017 Aug 9;8(41):70271-70280. doi: 10.18632/oncotarget.20082. eCollection 2017 Sep 19.
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Expression of CCL21 in Ewing sarcoma shows an inverse correlation with metastases and is a candidate target for immunotherapy.Cancer Immunol Immunother. 2016 Aug;65(8):995-1002. doi: 10.1007/s00262-016-1862-1. Epub 2016 Jul 1.
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Targeting endosialin/CD248 through antibody-mediated internalization results in impaired pericyte maturation and dysfunctional tumor microvasculature.Oncotarget. 2015 Sep 22;6(28):25429-40. doi: 10.18632/oncotarget.4559.
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pVHL/HIF-regulated CD70 expression is associated with infiltration of CD27+ lymphocytes and increased serum levels of soluble CD27 in clear cell renal cell carcinoma.Clin Cancer Res. 2015 Feb 15;21(4):889-98. doi: 10.1158/1078-0432.CCR-14-1425.
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Gene signature based on degradome-related genes can predict distal metastasis in cervical cancer patients.Tumour Biol. 2017 Jun;39(6):1010428317711895. doi: 10.1177/1010428317711895.
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Interaction with CCNH/CDK7 facilitates CtBP2 promoting esophageal squamous cell carcinoma (ESCC) metastasis via upregulating epithelial-mesenchymal transition (EMT) progression.Tumour Biol. 2015 Sep;36(9):6701-14. doi: 10.1007/s13277-015-3354-x. Epub 2015 Mar 29.
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CDK8 Selectively Promotes the Growth of Colon Cancer Metastases in the Liver by Regulating Gene Expression of TIMP3 and Matrix Metalloproteinases.Cancer Res. 2018 Dec 1;78(23):6594-6606. doi: 10.1158/0008-5472.CAN-18-1583. Epub 2018 Sep 5.
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The association of the angiopoietin/Tie-2 system with the development of metastasis and leukocyte migration in neuroendocrine tumors.Endocr Relat Cancer. 2010 Oct 5;17(4):897-908. doi: 10.1677/ERC-10-0020. Print 2010 Dec.
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TMED3 promotes cell proliferation and motility in breast cancer and is negatively modulated by miR-188-3p.Cancer Cell Int. 2019 Mar 29;19:75. doi: 10.1186/s12935-019-0791-4. eCollection 2019.
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Transmembrane protein 106A is silenced by promoter region hypermethylation and suppresses gastric cancer growth by inducing apoptosis.J Cell Mol Med. 2014 Aug;18(8):1655-66. doi: 10.1111/jcmm.12352. Epub 2014 Jun 28.
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Methylation of TMEM176A is an independent prognostic marker and is involved in human colorectal cancer development.Epigenetics. 2017 Jul 3;12(7):575-583. doi: 10.1080/15592294.2017.1341027. Epub 2017 Jul 5.
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Expression of decoy receptor 3 in liver tissue microarrays.Natl Med J India. 2008 Nov-Dec;21(6):275-8.
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ASPP2 suppresses squamous cell carcinoma via RelA/p65-mediated repression of p63.Proc Natl Acad Sci U S A. 2013 Oct 29;110(44):17969-74. doi: 10.1073/pnas.1309362110. Epub 2013 Oct 14.
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StarD13 3'-untranslated region functions as a ceRNA for TP53INP1 in prohibiting migration and invasion of breast cancer cells by regulating miR-125b activity.Eur J Cell Biol. 2018 Jan;97(1):23-31. doi: 10.1016/j.ejcb.2017.11.002. Epub 2017 Nov 11.
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TPPP3 Promotes Cell Proliferation, Invasion and Tumor Metastasis via STAT3/ Twist1 Pathway in Non-Small-Cell Lung Carcinoma.Cell Physiol Biochem. 2018;50(5):2004-2016. doi: 10.1159/000494892. Epub 2018 Nov 7.
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TRAP1 downregulation in human ovarian cancer enhances invasion and epithelial-mesenchymal transition.Cell Death Dis. 2016 Dec 15;7(12):e2522. doi: 10.1038/cddis.2016.400.
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Knockdown of TRB3 induces apoptosis in human lung adenocarcinoma cells through regulation of Notch 1 expression.Mol Med Rep. 2013 Jul;8(1):47-52. doi: 10.3892/mmr.2013.1453. Epub 2013 Apr 30.
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TRIM2 is a novel promoter of human colorectal cancer.Scand J Gastroenterol. 2019 Feb;54(2):210-218. doi: 10.1080/00365521.2019.1575463. Epub 2019 Mar 27.
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TRIM65 triggers -catenin signaling via ubiquitylation of Axin1 to promote hepatocellular carcinoma.J Cell Sci. 2017 Sep 15;130(18):3108-3115. doi: 10.1242/jcs.206623. Epub 2017 Jul 28.
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NF-kappa B genes have a major role in inflammatory breast cancer.BMC Cancer. 2008 Feb 4;8:41. doi: 10.1186/1471-2407-8-41.
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Tspan8 is expressed in breast cancer and regulates E-cadherin/catenin signalling and metastasis accompanied by increased circulating extracellular vesicles.J Pathol. 2019 Aug;248(4):421-437. doi: 10.1002/path.5281. Epub 2019 Jun 18.
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Occludin is a direct target of thyroid transcription factor-1 (TTF-1/NKX2-1).J Biol Chem. 2012 Aug 17;287(34):28790-801. doi: 10.1074/jbc.M112.367987. Epub 2012 Jul 2.
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Knockdown of Bone Morphogenetic Proteins Type 1a Receptor (BMPR1a) in Breast Cancer Cells Protects Bone from Breast Cancer-Induced Osteolysis by Suppressing RANKL Expression.Cell Physiol Biochem. 2018;45(5):1759-1771. doi: 10.1159/000487784. Epub 2018 Feb 23.
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Single-nucleotide polymorphism-mass array reveals commonly deleted regions at 3p22 and 3p14.2 associate with poor clinical outcome in esophageal squamous cell carcinoma.Int J Cancer. 2008 Aug 15;123(4):826-30. doi: 10.1002/ijc.23577.
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Clinical and pathological significance of Homo sapiens ceramide synthase 2 (CerS-2) in diverse human cancers.Biosci Rep. 2019 May 7;39(5):BSR20181743. doi: 10.1042/BSR20181743. Print 2019 May 31.
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Nucleoside Diphosphate Kinase Escalates A-to-C Mutations in MutT-Deficient Strains of Escherichia coli.J Bacteriol. 2019 Dec 6;202(1):e00567-19. doi: 10.1128/JB.00567-19. Print 2019 Dec 6.
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DDX49 is a novel biomarker and therapeutic target for lung cancer metastases.J Cell Mol Med. 2020 Jan;24(1):1141-1145. doi: 10.1111/jcmm.14734. Epub 2019 Nov 20.
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Significance of ELF3 mRNA expression for detection of lymph node metastases of colorectal cancer.Anticancer Res. 2012 Sep;32(9):3753-8.
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EPB41L5 is Associated With the Metastatic Potential of Low-grade Pancreatic Neuroendocrine Tumors.Cancer Genomics Proteomics. 2019 Sep-Oct;16(5):309-318. doi: 10.21873/cgp.20136.
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GNA13 expression promotes drug resistance and tumor-initiating phenotypes in squamous cell cancers.Oncogene. 2018 Mar;37(10):1340-1353. doi: 10.1038/s41388-017-0038-6. Epub 2017 Dec 19.
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HJURP Promotes Epithelial-to-Mesenchymal Transition via Upregulating SPHK1 in Hepatocellular Carcinoma.Int J Biol Sci. 2019 May 7;15(6):1139-1147. doi: 10.7150/ijbs.30904. eCollection 2019.
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Clinical significance and prognostic relevance of KRAS, BRAF, PI3K and TP53 genetic mutation analysis for resectable and unresectable colorectal liver metastases: A systematic review of the current evidence.Surg Oncol. 2018 Jun;27(2):280-288. doi: 10.1016/j.suronc.2018.05.012. Epub 2018 May 8.
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Unconventional myosin VIIA promotes melanoma progression.J Cell Sci. 2018 Feb 22;131(4):jcs209924. doi: 10.1242/jcs.209924.
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Hypoxia and loss of PHD2 inactivate stromal fibroblasts to decrease tumour stiffness and metastasis.EMBO Rep. 2015 Oct;16(10):1394-408. doi: 10.15252/embr.201540107. Epub 2015 Aug 31.
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Blocking podoplanin suppresses growth and pulmonary metastasis of human malignant melanoma.BMC Cancer. 2019 Jun 17;19(1):599. doi: 10.1186/s12885-019-5808-9.
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Caveolin-1 promotes invasion and metastasis by upregulating Pofut1 expression in mouse hepatocellular carcinoma.Cell Death Dis. 2019 Jun 17;10(7):477. doi: 10.1038/s41419-019-1703-1.
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Twist on a classic: vitamin D and hypercalcaemia of malignancy.BMJ Case Rep. 2017 Nov 23;2017:bcr2017220819. doi: 10.1136/bcr-2017-220819.
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Deficiency of the adrenomedullin-RAMP3 system suppresses metastasis through the modification of cancer-associated fibroblasts.Oncogene. 2020 Feb;39(9):1914-1930. doi: 10.1038/s41388-019-1112-z. Epub 2019 Nov 21.
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Enhanced intratumoral expression of RNF2 is a favorable prognostic factor for patients with cutaneous melanoma?.Oncotarget. 2018 Apr 3;9(25):17656-17663. doi: 10.18632/oncotarget.24825. eCollection 2018 Apr 3.
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Novel role of Snail 1 in promoting tumor neoangiogenesis.Biosci Rep. 2019 May 10;39(5):BSR20182161. doi: 10.1042/BSR20182161. Print 2019 May 31.
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BAG3-mediated miRNA let-7g and let-7i inhibit proliferation and enhance apoptosis of human esophageal carcinoma cells by targeting the drug transporter ABCC10.Cancer Lett. 2016 Feb 1;371(1):125-33. doi: 10.1016/j.canlet.2015.11.031. Epub 2015 Dec 3.
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