General Information of Disease (ID: DIS86UK6)

Disease Name Metastatic malignant neoplasm
Synonyms malignant metastatic neoplasm; metastatic neoplasm, malignant; metastatic malignant neoplasm; metastatic cancer
Disease Class 2D50-2E09: Metastatic malignant neoplasm
Definition
A malignant tumor that has spread from its original (primary) site of growth to another site close to or distant from the primary site.|Note that we currently treat secondary neoplasms as being neoplastic diseases that are derived from neoplasm; classes such as 'neoplasm', 'carcinoma' are implicitly primary. This may change in future.
Disease Hierarchy
DISIV4KF: Secondary malignant neoplasm
DISFAXQ5: Metastatic neoplasm
DIS86UK6: Metastatic malignant neoplasm
ICD Code
ICD-11
ICD-11: 2D50-2E09
Disease Identifiers
MONDO ID
MONDO_0024880
UMLS CUI
C2939419
MedGen ID
422475
SNOMED CT ID
128462008

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 1 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Irsogladine DM0TGTY Approved Small molecular drug [1]
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This Disease is Treated as An Indication in 5 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
BGB-324 DMDI43Y Phase 2 siRNA drug [2]
INCAGN01949 DMK7OHI Phase 2 Antibody [3]
H-103 DMRCHOU Phase 1 NA [4]
HER2-CAR T Cells DMZXDBN Phase 1 CAR T Cell Therapy [5]
ICasp9M28z T cell DMY6V5T Phase 1 CAR T Cell Therapy [6]
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This Disease is Treated as An Indication in 4 Investigative Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
DCC-2909 DMC38WO Investigative NA [7]
Integrin alpha 5/beta 1 DMF5IVB Investigative NA [7]
Recombinant uteroglobin DMTICZA Investigative NA [7]
ZP-103 DMTW3VE Investigative NA [7]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 595 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
ABCG1 TTMWDGU Limited Biomarker [8]
ADAM10 TTVXEGU Limited Altered Expression [9]
ADAMTS5 TTXSU2Y Limited Altered Expression [10]
ALPI TTHYMUV Limited Biomarker [11]
ASRGL1 TT4WT91 Limited Altered Expression [12]
AZGP1 TTUPYLV Limited Biomarker [13]
BRS3 TTKYEPM Limited Biomarker [14]
CAMKK2 TTV298Y Limited Biomarker [15]
CCNE1 TTCEJ4F Limited Biomarker [16]
CCR4 TT7HQD0 Limited Altered Expression [17]
CCR5 TTJIH8Q Limited Altered Expression [18]
CD6 TTMF6KC Limited Biomarker [19]
CD96 TT83C4X Limited Biomarker [20]
CDC20 TTBKFDV Limited Biomarker [21]
CDK19 TTNABU9 Limited Altered Expression [22]
CPE TTXPWO6 Limited Biomarker [23]
CRLF1 TT6YF5K Limited Biomarker [24]
CRY1 TT5MLZR Limited Altered Expression [25]
CRY2 TTAO58M Limited Altered Expression [25]
CTAG1A TTE5ITK Limited Biomarker [26]
CTCFL TTY0RZT Limited Biomarker [27]
CTSK TTDZN01 Limited Biomarker [28]
DEPDC1 TT8S9CM Limited Altered Expression [29]
DICER1 TTTEOPU Limited Altered Expression [30]
DKK2 TTST5KX Limited Biomarker [31]
EEF2K TT1QFLA Limited Biomarker [32]
F13A1 TTXI2RA Limited Altered Expression [33]
FES TTLBY21 Limited Altered Expression [34]
FGR TTPOGS1 Limited Biomarker [35]
FNDC1 TTQJCV8 Limited Altered Expression [36]
FYN TT2B9KF Limited Biomarker [37]
HAX1 TT21BYA Limited Altered Expression [38]
HNRNPA2B1 TT8UPW6 Limited Altered Expression [39]
HTATIP2 TTC6IX5 Limited Biomarker [40]
HTR1D TT6MSOK Limited Biomarker [41]
IAPP TTHN8EM Limited Biomarker [11]
IFNAR1 TTSYFMA Limited Altered Expression [42]
IL13RA2 TTMPZ7V Limited Altered Expression [43]
IL2RB TT9721Y Limited Biomarker [44]
IL7R TTAWI51 Limited Biomarker [45]
ITGAL TT48WR6 Limited Biomarker [46]
ITK TT3C80U Limited Biomarker [47]
LAG3 TTNVXAW Limited Biomarker [48]
LAMP1 TTC214J Limited Biomarker [49]
LAPTM4B TTEJQT0 Limited Altered Expression [50]
LGMN TTPTWV5 Limited Biomarker [51]
LIFR TTID542 Limited Altered Expression [52]
LIN28A TTO50LN Limited Altered Expression [53]
LPAR2 TTB7Y8I Limited Biomarker [14]
LTB4R2 TTVJX54 Limited Biomarker [54]
MAGEA2 TTOZT28 Limited Genetic Variation [55]
MALT1 TTCI81G Limited Biomarker [56]
MMP15 TTNSTO3 Limited Altered Expression [57]
NAAA TTMN4HY Limited Biomarker [58]
NCR1 TTQNRJM Limited Biomarker [59]
NUAK1 TT65FL0 Limited Biomarker [60]
PARP3 TTD8MEH Limited Biomarker [61]
PBRM1 TTH8ZRL Limited Genetic Variation [62]
PF4 TTSG7Q5 Limited Biomarker [63]
PFKFB3 TTTHMQJ Limited Biomarker [64]
PGD TTZ3IFB Limited Biomarker [65]
PI4KA TTCUS9F Limited Biomarker [66]
PLD2 TTRLMKF Limited Altered Expression [67]
PPP3CA TTA4LDE Limited Biomarker [68]
PRKAR2B TTW4Y2M Limited Altered Expression [69]
PRKDC TTK3PY9 Limited Biomarker [70]
PRMT1 TTVOJAI Limited Altered Expression [71]
PSIP1 TTH9LDP Limited Altered Expression [72]
PSMB8 TTEAD9J Limited Altered Expression [73]
RGS6 TTJ96M8 Limited Biomarker [74]
RIPK2 TTCQ2E5 Limited Biomarker [75]
ROR2 TTUDPCI Limited Altered Expression [76]
SLC12A5 TTH6UZY Limited Biomarker [77]
SLC22A1 TTM5Q4V Limited Altered Expression [78]
SLC38A3 TTMAVJQ Limited Altered Expression [79]
SRPK2 TTCZEJ9 Limited Altered Expression [80]
SSTR2 TTZ6T9E Limited Altered Expression [81]
STC2 TT4EFTR Limited Altered Expression [82]
SULF2 TTLQTHB Limited Biomarker [83]
SYK TT2HUPM Limited Biomarker [84]
TAAR1 TTIU98M Limited Altered Expression [85]
TDGF1 TTN7HMG Limited Altered Expression [86]
TIGIT TTWNL74 Limited Biomarker [87]
UGT1A1 TT34ZAF Limited Biomarker [88]
WNT7A TT8NARC Limited Altered Expression [89]
AGR2 TT9K86S Disputed Biomarker [90]
AXL TTZPY6J Disputed Biomarker [91]
BMP4 TTD3BSX Disputed Biomarker [92]
COL18A1 TT63DI9 Disputed Altered Expression [93]
CSF1 TT0IQER Disputed Biomarker [94]
CYP19A1 TTSZLWK Disputed Biomarker [95]
EIF5A2 TTH53G9 Disputed Biomarker [96]
EPHA2 TTRJB2G Disputed Biomarker [97]
FLT1 TT1VAUK Disputed Altered Expression [98]
FSHR TTZFDBT Disputed Altered Expression [99]
HSPA5 TTW26OG Disputed Biomarker [100]
PLG TTP86E2 Disputed Altered Expression [101]
PTK2B TTTEFBV Disputed Altered Expression [102]
RICTOR TT143WL Disputed Altered Expression [103]
SERPINF1 TTR59S1 Disputed Biomarker [104]
TIAM1 TTNU6I5 Disputed Biomarker [105]
TNFRSF25 TTDV6BQ Disputed Biomarker [106]
VDR TTK59TV Disputed Genetic Variation [107]
ACR TTAHE2N moderate Biomarker [108]
ACVR2A TTX2DRI moderate Altered Expression [109]
ADAM9 TTTYQNS moderate Biomarker [110]
AKR1C3 TT5ZWB6 moderate Altered Expression [111]
ANO1 TTOJI4S moderate Biomarker [112]
BGN TT0JPVF moderate Biomarker [113]
CCL21 TTLZK1U moderate Altered Expression [114]
CD163 TTTZ9DE moderate Biomarker [64]
CD19 TTW640A moderate Biomarker [26]
CD248 TTYJWT7 moderate Biomarker [115]
CD70 TTNCIE0 moderate Altered Expression [116]
CD74 TTCMYP9 moderate Genetic Variation [117]
CDK7 TTQYF7G moderate Biomarker [118]
CDK8 TTBJR4L moderate Biomarker [119]
CDKN2C TTBRUGA moderate Genetic Variation [120]
CHKA TT10AWB moderate Altered Expression [121]
CLCN3 TT8XNZ7 moderate Biomarker [122]
CLDN18 TT6PKBX moderate Altered Expression [123]
CNTN1 TTPR8FK moderate Biomarker [124]
COL1A2 TTUABC1 moderate Altered Expression [125]
CSPG4 TT7MYXI moderate Altered Expression [126]
CTSS TTUMQVO moderate Altered Expression [127]
CX3CL1 TT1OFBQ moderate Biomarker [128]
CXCR1 TTMWT8Z moderate Biomarker [129]
CYP24A1 TT82UI1 moderate Altered Expression [130]
E2F3 TTWIJYH moderate Biomarker [131]
EGFL7 TT7WD0H moderate Altered Expression [132]
EML4 TT92GY4 moderate Genetic Variation [133]
ENTPD1 TTYM8DJ moderate Biomarker [134]
EREG TTYSB89 moderate Altered Expression [135]
EYA2 TTUY9C6 moderate Biomarker [136]
F2RL2 TTVSEBF moderate Biomarker [137]
FOXQ1 TTEJZOL moderate Biomarker [138]
FST TTDNM9W moderate Biomarker [139]
FUT3 TTUPAD7 moderate Biomarker [140]
GDF2 TTAP4T1 moderate Altered Expression [141]
GHR TTHJWYD moderate Biomarker [142]
GJB1 TTSJIRP moderate Biomarker [143]
GLUL TTURQ2G moderate Biomarker [144]
GNAQ TTL1SRG moderate Altered Expression [145]
GPNMB TT7315J moderate Altered Expression [146]
GPR12 TT3IPW2 moderate Biomarker [147]
GZMB TTKEPHX moderate Altered Expression [148]
HDGF TTKGV26 moderate Altered Expression [149]
HSF1 TTN6STZ moderate Biomarker [150]
HSPA9 TTMTPG3 moderate Biomarker [151]
IL25 TTVMO5W moderate Biomarker [152]
IMP3 TTEJA2R moderate Altered Expression [153]
ITGA4 TTJMF9P moderate Altered Expression [154]
ITGAE TTH0Z37 moderate Altered Expression [155]
ITGB3 TTJA1ZO moderate Altered Expression [156]
KAT2B TTVK7SB moderate Biomarker [157]
KCNJ6 TTTIBVP moderate Genetic Variation [158]
KLK6 TTLPF4X moderate Altered Expression [159]
KMT5A TTGC95K moderate Biomarker [160]
LATS2 TTML7FG moderate Biomarker [161]
LGR5 TTTSGRH moderate Altered Expression [162]
LIMK1 TTWL9TY moderate Altered Expression [163]
LIPA TTS8T1M moderate Biomarker [164]
LPAR3 TTE2YJR moderate Biomarker [165]
LRP5 TT7VMG4 moderate Biomarker [166]
LY6K TT5GKHN moderate Altered Expression [167]
MAP3K7 TTJQT60 moderate Biomarker [168]
MAPK12 TTYT93M moderate Biomarker [169]
MBTPS1 TTNSM2I moderate Biomarker [170]
MELK TTBZOTY moderate Biomarker [171]
MMP10 TTXLEG7 moderate Biomarker [172]
MMP12 TTXZ0KQ moderate Altered Expression [95]
MSI1 TTSM4BA moderate Altered Expression [173]
MTAP TTDBX7N moderate Genetic Variation [174]
MYLK TT18ETS moderate Biomarker [175]
NEDD4 TT1QU6G moderate Biomarker [176]
NLRP1 TTQX29T moderate Altered Expression [177]
NOTCH3 TTVX7IA moderate Altered Expression [178]
NRP2 TTRXUVC moderate Genetic Variation [179]
NTSR1 TTTUMEP moderate Altered Expression [180]
ORAI1 TTE76YK moderate Altered Expression [181]
PARG TT39J16 moderate Biomarker [182]
PDE4D TTSKMI8 moderate Biomarker [183]
PDGFD TTSN0GA moderate Biomarker [184]
PDX1 TT8SGZK moderate Biomarker [185]
PINX1 TT4FJ3A moderate Biomarker [186]
PKN3 TTW3P4R moderate Altered Expression [187]
PLA2G7 TTDNFMT moderate Biomarker [188]
PPM1D TTENJAB moderate Altered Expression [189]
PPY TTIB95A moderate Biomarker [190]
PTPN14 TTNIR6C moderate Altered Expression [191]
RACK1 TTJ10AL moderate Biomarker [192]
RASA1 TTPNZ1F moderate Biomarker [193]
RHD TTLCKI8 moderate Biomarker [194]
ROBO1 TTND1YP moderate Biomarker [195]
ROCK1 TTZN7RP moderate Biomarker [196]
RPS6KA3 TTUM2ZR moderate Biomarker [197]
SEMA4D TT5UT28 moderate Biomarker [198]
SENP1 TTW9HY5 moderate Genetic Variation [199]
SHH TTIENCJ moderate Genetic Variation [200]
SIRT2 TTLKF5M moderate Biomarker [201]
SLC22A3 TTG2UMS moderate Biomarker [47]
SLC7A5 TTPH2JB moderate Altered Expression [202]
SLIT2 TTDWK85 moderate Altered Expression [195]
SMPD1 TTJTM88 moderate Biomarker [203]
SOX5 TTXHSZK moderate Biomarker [204]
TAGLN TTDRZ9H moderate Altered Expression [205]
TBX21 TTNF9PH moderate Biomarker [206]
TDO2 TTXNCBV moderate Biomarker [207]
TERF1 TT1Y6J2 moderate Altered Expression [208]
TERF2 TT5XSLT moderate Altered Expression [209]
TKTL1 TTNQ1J3 moderate Altered Expression [210]
TLR7 TTRJ1K4 moderate Biomarker [211]
TNFRSF10A TT5WLRX moderate Altered Expression [212]
TNFRSF12A TTKPS7V moderate Biomarker [213]
TRPC5 TT32NQ1 moderate Biomarker [214]
TSPAN7 TTMT6VE moderate Biomarker [215]
ACKR3 TTRQJTC Strong Biomarker [216]
ADAM8 TTQWYMD Strong Biomarker [217]
ADORA1 TTK25J1 Strong Altered Expression [218]
AFP TTCFEA1 Strong Altered Expression [219]
AIF1 TT12MEP Strong Biomarker [220]
ALCAM TT2AFT6 Strong Biomarker [221]
ALOX15 TTN9T81 Strong Altered Expression [222]
AMACR TTLN1AP Strong Altered Expression [223]
ANG TTURHFP Strong Biomarker [224]
ANGPT1 TTWNQ1T Strong Biomarker [225]
ANGPTL4 TTWALY5 Strong Biomarker [226]
ANXA2 TT4YANI Strong Altered Expression [227]
ARRB1 TTMVD4A Strong Biomarker [228]
ASPA TT6TLZP Strong Genetic Variation [229]
ATAD2 TT9A0HI Strong Biomarker [230]
ATAT1 TTWUHQ1 Strong Altered Expression [231]
AURKA TTPS3C0 Strong Biomarker [232]
B2M TTY7FKA Strong Biomarker [233]
BACH1 TT2ME4S Strong Altered Expression [234]
BAK1 TTFM7V0 Strong Genetic Variation [235]
BCAT1 TTES57P Strong Altered Expression [236]
BIRC7 TTHZ8TA Strong Biomarker [237]
BMP6 TT07RIB Strong Altered Expression [238]
BSG TT5UJWD Strong Posttranslational Modification [239]
BST2 TT90BJT Strong Altered Expression [240]
BTG1 TTL7N2W Strong Altered Expression [241]
BUB1 TT78309 Strong Altered Expression [242]
C5AR1 TTHXFA1 Strong Altered Expression [243]
CA12 TTSYM0R Strong Biomarker [244]
CALCR TTLWS2O Strong Biomarker [245]
CCL20 TT2XAZY Strong Altered Expression [246]
CCR1 TTC24WT Strong Altered Expression [247]
CCR6 TTFDB30 Strong Altered Expression [246]
CCR7 TT2GIDQ Strong Altered Expression [248]
CCR9 TTIPS8B Strong Altered Expression [249]
CD1A TTBGTFN Strong Biomarker [250]
CD200 TT0BE68 Strong Altered Expression [251]
CD22 TTM6QSK Strong Biomarker [252]
CD24 TTCTYNP Strong Altered Expression [253]
CD276 TT6CQUM Strong Biomarker [254]
CD300A TTI2YFK Strong Altered Expression [255]
CD58 TT5KSBY Strong Biomarker [256]
CD83 TTT9MRQ Strong Biomarker [257]
CD9 TTZEIBV Strong Altered Expression [258]
CDH2 TT1WS0T Strong Biomarker [259]
CDH6 TT9QHUK Strong Altered Expression [260]
CDKN1C TTBSUAR Strong Altered Expression [261]
CEACAM1 TTA9CK4 Strong Biomarker [262]
CEACAM6 TTIGH2W Strong Biomarker [263]
CEBPB TTUI35N Strong Altered Expression [264]
CMA1 TT8VUE0 Strong Altered Expression [265]
CTSC TT4H0V2 Strong Biomarker [266]
CXCR2 TT30C9G Strong Biomarker [267]
CXCR3 TT1UCIJ Strong Biomarker [268]
CXCR4 TTBID49 Strong Biomarker [269]
CXCR6 TT2BVUA Strong Biomarker [270]
CYP3A5 TTHS0OK Strong Biomarker [88]
DAG1 TT4X7PG Strong Biomarker [271]
DCN TTB3XAN Strong Biomarker [272]
DHCR24 TTTK0NH Strong Biomarker [273]
DHFR TTYZVDJ Strong Altered Expression [274]
DLK1 TTF4AVB Strong Biomarker [275]
DLL4 TTV23LH Strong Altered Expression [276]
DPYD TTZPS91 Strong Altered Expression [277]
EGF TTED8JB Strong Altered Expression [278]
EIF2AK3 TT79U1M Strong Biomarker [279]
EIF4E TTZGCP6 Strong Posttranslational Modification [280]
ENPP2 TTSCIM2 Strong Altered Expression [281]
EPHA3 TTHS2LR Strong Biomarker [282]
EPHA8 TTHZ2LW Strong Biomarker [283]
EPHB3 TT5LM7U Strong Altered Expression [284]
EPHB4 TTI4ZX2 Strong Altered Expression [285]
ESRRA TTPNQAC Strong Biomarker [286]
ETS1 TTTGPSD Strong Biomarker [10]
ETS2 TT9AH0M Strong Altered Expression [287]
F2R TTL935N Strong Biomarker [56]
F2RL3 TTD0652 Strong Biomarker [288]
F7 TTF0EGX Strong Biomarker [289]
FER TTRA9G0 Strong Altered Expression [290]
FFAR1 TTB8FUC Strong Altered Expression [291]
FGF4 TTCEKVZ Strong Biomarker [292]
FGFR4 TT1KX2S Strong Biomarker [283]
FKBP5 TT0J5KQ Strong Biomarker [293]
FOSL1 TTY8LZG Strong Biomarker [294]
FOXC1 TTNT3YA Strong Altered Expression [295]
FOXC2 TTLBAP1 Strong Biomarker [296]
FOXJ2 TTV1FDA Strong Altered Expression [297]
FPR2 TTOJ1NF Strong Biomarker [298]
FURIN TTH9WF6 Strong Altered Expression [299]
FUT4 TTNV1KZ Strong Altered Expression [300]
FZD7 TTUQMO5 Strong Biomarker [301]
GATA3 TT45KOB Strong Biomarker [302]
GCK TTDLNGZ Strong Biomarker [303]
GMNN TT390KA Strong Altered Expression [304]
GNA11 TTSRXJW Strong Genetic Variation [305]
GNRH1 TT0ID4A Strong Altered Expression [306]
GPER1 TTDSB34 Strong Altered Expression [307]
GPI TT19JIZ Strong Biomarker [308]
GPR119 TT7QNVC Strong Biomarker [309]
GPR18 TTSLJAR Strong Biomarker [309]
GPR183 TTME5YJ Strong Biomarker [309]
GPR34 TTVXSTQ Strong Biomarker [309]
GRHL2 TTUGH4C Strong Altered Expression [310]
GRM1 TTVBPDM Strong Biomarker [311]
GUCY2C TTLDPRG Strong Biomarker [312]
GUSB TTHS7CM Strong Biomarker [313]
HCAR2 TTWNV8U Strong Altered Expression [314]
HCN1 TTNB6UQ Strong Biomarker [88]
HCRTR1 TT60Q8D Strong Altered Expression [315]
HHAT TT1VNCG Strong Biomarker [316]
HLA-G TTLKFB3 Strong Biomarker [317]
HMGA1 TTBA219 Strong Biomarker [318]
HNF4A TT2F3CD Strong Biomarker [319]
HOXA5 TTXSVQP Strong Biomarker [320]
HOXB13 TTZ6I58 Strong Biomarker [321]
HPN TT25MVL Strong Biomarker [322]
HRC TTR4FKD Strong Biomarker [323]
HSP90AA1 TT78R5H Strong Biomarker [324]
HSPA8 TTMQL3K Strong Biomarker [325]
HTRA1 TT8POQR Strong Biomarker [326]
HTT TTIWZ0O Strong Genetic Variation [327]
ID1 TTBXVDE Strong Biomarker [328]
IGFBP2 TTU4QSN Strong Biomarker [329]
IGFBP5 TTDWEA8 Strong Altered Expression [330]
IL23A TTC1GLB Strong Biomarker [331]
IL24 TT1EPXZ Strong Altered Expression [332]
ILK TT7ALZG Strong Biomarker [333]
IMPDH2 TTTB4UP Strong Altered Expression [334]
ISG15 TTVOH3T Strong Biomarker [335]
ITGA2 TTSJ542 Strong Altered Expression [336]
ITGA5 TTHIZP9 Strong Altered Expression [337]
ITGA6 TT165T3 Strong Biomarker [338]
ITGAM TTB69FJ Strong Biomarker [339]
ITGAV TTT1R2L Strong Biomarker [340]
ITGB1 TTBVIQC Strong Altered Expression [341]
ITGB6 TTKQSXZ Strong Biomarker [342]
ITGB8 TTIF29E Strong Biomarker [343]
KDM3A TTKXS4A Strong Biomarker [344]
KDM5B TTCLI75 Strong Altered Expression [345]
KIF26B TTQWICZ Strong Altered Expression [346]
KISS1R TT3KBZY Strong Altered Expression [347]
KIT TTX41N9 Strong Altered Expression [348]
KLF4 TTTI53X Strong Altered Expression [349]
KLK2 TTJLNAW Strong Biomarker [350]
KLK4 TT4319X Strong Biomarker [351]
KLK5 TTULSEW Strong Altered Expression [352]
KLK7 TTE6GTB Strong Altered Expression [352]
KLRK1 TTLRN4A Strong Biomarker [353]
KRT6A TT2FX8W Strong Biomarker [354]
L1CAM TTC9D3K Strong Biomarker [355]
LGALS1 TTO3NYT Strong Biomarker [356]
LGR4 TTY6C71 Strong Altered Expression [357]
LOXL2 TTFSUHX Strong Biomarker [358]
LPAR1 TTQ6S1K Strong Biomarker [359]
MAGEA1 TT63M7Q Strong Biomarker [360]
MAGEA3 TTWSKHD Strong Biomarker [361]
MAGEA4 TT9EQUY Strong Biomarker [361]
MAP3K1 TTW8TJI Strong Biomarker [362]
MAP3K8 TTGECUM Strong Altered Expression [363]
MAP4K3 TTI0AHJ Strong Biomarker [303]
MAP4K4 TT6NI13 Strong Biomarker [364]
MCAM TTHRE05 Strong Altered Expression [365]
MDK TTV8UE7 Strong Biomarker [366]
MERTK TTO7LKR Strong Altered Expression [367]
MLANA TT362RB Strong Biomarker [368]
MLH1 TTISG27 Strong Biomarker [369]
MME TT5TKPM Strong Biomarker [370]
MMP1 TTMX39J Strong Altered Expression [371]
MMP14 TTJ4QE7 Strong Biomarker [372]
MMP16 TTNP4CU Strong Biomarker [373]
MMP8 TTGA1IV Strong Altered Expression [374]
MSLN TT4RXME Strong Biomarker [375]
MST1R TTBQ3OC Strong Biomarker [376]
MTDH TTH6SA5 Strong Altered Expression [377]
MUC16 TTC1PS3 Strong Altered Expression [378]
NCOA3 TT124R0 Strong Altered Expression [379]
NDUFA13 TTRU1NG Strong Biomarker [380]
NECTIN4 TTPO9EG Strong Altered Expression [381]
NEDD9 TT1UREA Strong Altered Expression [382]
NES TTHZ752 Strong Altered Expression [302]
NISCH TT789FN Strong Biomarker [383]
NOTCH4 TTXDIK2 Strong Altered Expression [276]
NPTX2 TTNJ5A6 Strong Altered Expression [384]
NR1I3 TTRANFM Strong Biomarker [385]
NR4A3 TTJQB49 Strong Biomarker [386]
NRP1 TTIPJCB Strong Altered Expression [387]
NT5E TTK0O6Y Strong Altered Expression [388]
OLFM4 TTK1CX7 Strong Altered Expression [389]
OSM TTIVXSE Strong Biomarker [390]
P2RX7 TT473XN Strong Biomarker [391]
P2RY10 TTMFOU6 Strong Biomarker [309]
PADI4 TTQHAXM Strong Altered Expression [392]
PAWR TT3I4WV Strong Biomarker [288]
PCSK1 TTED9LZ Strong Biomarker [354]
PCSK9 TTNIZ2B Strong Biomarker [393]
PDCD1LG2 TTW14O3 Strong Altered Expression [394]
PDGFRB TTI7421 Strong Altered Expression [395]
PIKFYVE TTA4M1N Strong Biomarker [396]
PIM3 TTCGOIN Strong Biomarker [397]
PIN1 TTJNTSI Strong Altered Expression [398]
PKN1 TTSL41O Strong Biomarker [399]
PLAUR TTNOSTX Strong Genetic Variation [400]
PLCG1 TT6T4JI Strong Biomarker [401]
PLEKHA5 TTCDZMO Strong Biomarker [402]
PLK1 TTH4IP0 Strong Biomarker [403]
PLOD1 TTEKJP3 Strong Altered Expression [404]
PPM1A TTLA7IX Strong Altered Expression [405]
PRAME TTPH7T0 Strong Biomarker [406]
PRSS8 TTT4N0Q Strong Biomarker [407]
PSCA TT9T4AV Strong Altered Expression [408]
PSMB10 TTPNACM Strong Biomarker [409]
PTGER3 TTPNGDE Strong Biomarker [410]
PTK2 TTON5IT Strong Biomarker [411]
PTK6 TT6TH8V Strong Altered Expression [412]
PTP4A1 TTA8GFO Strong Altered Expression [413]
PTP4A2 TT1MHKD Strong Altered Expression [414]
PTPRB TT64I9Q Strong Biomarker [415]
PYGM TTZHY6R Strong Genetic Variation [416]
RAD51 TTC0G1L Strong Altered Expression [417]
RALBP1 TTVSRUA Strong Altered Expression [418]
RECK TTRZBW7 Strong Posttranslational Modification [419]
RENBP TTZCG0Q Strong Biomarker [420]
RHO TTH0KSX Strong Biomarker [421]
RIPK1 TTVJHX8 Strong Altered Expression [418]
ROCK2 TTGWKQJ Strong Genetic Variation [422]
ROR1 TTDEJAU Strong Biomarker [423]
RORB TTGB2LZ Strong Altered Expression [424]
ROS1 TTSZ6Y3 Strong Biomarker [425]
RPE65 TTBOH16 Strong Biomarker [426]
RPS6KA1 TTIXKA4 Strong Biomarker [427]
RRM2 TT1S4LJ Strong Biomarker [428]
RSF1 TTMP86V Strong Altered Expression [429]
RUNX2 TTD6SZ8 Strong Biomarker [430]
RUNX3 TTKCVO7 Strong Biomarker [431]
S100B TTQ0V86 Strong Altered Expression [432]
SCGB2A2 TT1W3RE Strong Altered Expression [433]
SDHD TTVH9W8 Strong Genetic Variation [434]
SELPLG TTS5K8U Strong Altered Expression [435]
SETD2 TTPC3H4 Strong Genetic Variation [436]
SFTPD TTGLMU7 Strong Genetic Variation [437]
SGCB TTEDCQ0 Strong Biomarker [438]
SGCG TTSMT9W Strong Altered Expression [439]
SH3GL1 TTTYNAM Strong Biomarker [440]
SIK3 TTW6L4V Strong Altered Expression [441]
SKP2 TT5B2EO Strong Altered Expression [442]
SLC16A1 TTN1J82 Strong Altered Expression [265]
SLC16A3 TTG6VD5 Strong Altered Expression [265]
SLC19A1 TT09I7D Strong Altered Expression [274]
SLC1A5 TTF7WRM Strong Altered Expression [443]
SLC22A2 TT0XOJN Strong Biomarker [444]
SLC26A4 TT7X02I Strong Altered Expression [445]
SLC39A6 TTZN1CF Strong Altered Expression [446]
SLC6A12 TTQBMPI Strong Posttranslational Modification [447]
SLC9A1 TTGSEFH Strong Genetic Variation [448]
SLCO1B3 TTU86P0 Strong Genetic Variation [449]
SLCO2B1 TTDL3UZ Strong Genetic Variation [449]
SMYD3 TTKLJYX Strong Biomarker [450]
SNCG TT5TQNZ Strong Altered Expression [451]
SOST TTYRO4F Strong Biomarker [452]
SPDEF TT2ZUPY Strong Biomarker [453]
SRC TT6PKBN Strong Altered Expression [454]
SRD5A2 TTT02K8 Strong Genetic Variation [455]
SRGN TTCHB06 Strong Biomarker [456]
SSTR1 TTIND6G Strong Biomarker [457]
SSTR4 TTAE1BR Strong Biomarker [14]
SSTR5 TT2BC4G Strong Biomarker [457]
ST14 TTPRO7W Strong Biomarker [458]
STC1 TTDLUER Strong Biomarker [459]
STK33 TTP34DQ Strong Posttranslational Modification [460]
STMN1 TT7W5OT Strong Altered Expression [461]
STYK1 TTRMCYJ Strong Biomarker [462]
SYVN1 TT8XKYM Strong Genetic Variation [463]
TACSTD2 TTP2HE5 Strong Altered Expression [464]
TBL1XR1 TTYXT16 Strong Altered Expression [465]
TEK TT9VGXW Strong Biomarker [466]
TFPI TT068JH Strong Biomarker [467]
TGFBR1 TTP4520 Strong Biomarker [468]
TGM2 TT2F4OL Strong Biomarker [469]
TMEM97 TT9NXW4 Strong Altered Expression [470]
TMPRSS2 TT1GM2Z Strong Genetic Variation [471]
TNC TTUCPMY Strong Altered Expression [472]
TNFRSF11A TT3K9S2 Strong Altered Expression [473]
TNFRSF11B TT2CJ75 Strong Altered Expression [473]
TNFSF12 TTBTDM1 Strong Altered Expression [474]
TNFSF14 TTKVENM Strong Biomarker [475]
TNFSF4 TTBW580 Strong Biomarker [476]
TNNC1 TT8RDXP Strong Biomarker [477]
TOP2A TTCGY2K Strong Altered Expression [478]
TPO TT52XDZ Strong Altered Expression [479]
TPT1 TT3PTB6 Strong Biomarker [480]
TRIM27 TTTO3QN Strong Biomarker [298]
TRIM28 TTQ2BKV Strong Biomarker [481]
TRIM59 TT613U4 Strong Biomarker [482]
TRPM1 TTTDAI9 Strong Biomarker [424]
TRPM4 TTJ2HKA Strong Altered Expression [483]
TRPM7 TTFPVZO Strong Biomarker [484]
TRPV2 TTBECWA Strong Altered Expression [485]
TSG101 TTHU7JA Strong Biomarker [486]
TSHR TT6NYJA Strong Altered Expression [487]
TSPO TTPTXIN Strong Altered Expression [488]
TYMP TTO0IB8 Strong Genetic Variation [489]
TYMS TTP1UKZ Strong Altered Expression [490]
TYRO3 TTIEMFN Strong Altered Expression [491]
TYRP1 TTFRV98 Strong Genetic Variation [492]
ULK1 TT4D7MJ Strong Genetic Variation [493]
UTS2R TTW5UDX Strong Genetic Variation [494]
VEGFD TTOM5H4 Strong Biomarker [495]
VWF TT3SZBT Strong Biomarker [496]
WEE1 TTJFOAL Strong Genetic Variation [497]
ZNF217 TTY3BRA Strong Altered Expression [498]
ABCB1 TT3OT40 Definitive Biomarker [499]
ANPEP TTPHMWB Definitive Biomarker [500]
AR TTKPW01 Definitive Genetic Variation [501]
AREG TT76B3W Definitive Biomarker [502]
ATF4 TTQCKWT Definitive Biomarker [503]
BMPR2 TTGKF90 Definitive Altered Expression [504]
CA9 TT2LVK8 Definitive Altered Expression [505]
CALCA TTVSFJW Definitive Biomarker [506]
CALR TTUZ7OA Definitive Biomarker [245]
CCN1 TTPK79J Definitive Altered Expression [507]
CD36 TTPJMCU Definitive Biomarker [508]
CDH11 TTRGWZC Definitive Altered Expression [509]
CSNK2A2 TT7GR5W Definitive Biomarker [510]
CTLA4 TTI2S1D Definitive Biomarker [511]
CXCL1 TTLK1RW Definitive Biomarker [512]
CXCL11 TTWG0RE Definitive Biomarker [513]
CXCL12 TT4UGTF Definitive Altered Expression [514]
CXCL2 TTZF0K2 Definitive Altered Expression [515]
DDR2 TTU98HG Definitive Biomarker [516]
DKK1 TTE3RAC Definitive Altered Expression [517]
DPP4 TTDIGC1 Definitive Altered Expression [518]
EPHB2 TTKPV6O Definitive Biomarker [519]
EZH2 TT9MZCQ Definitive Biomarker [520]
F3 TT38MDJ Definitive Altered Expression [521]
FOXM1 TTD3KOX Definitive Altered Expression [522]
FOXO1 TTLRVIA Definitive Biomarker [523]
FSCN1 TTTRS9B Definitive Biomarker [524]
FZD10 TTP1S2F Definitive Biomarker [525]
GDF15 TT4MXVG Definitive Altered Expression [526]
HMGB1 TTWQYB7 Definitive Biomarker [495]
HPSE TTR7GJO Definitive Biomarker [527]
HSPB3 TTLH8WG Definitive Biomarker [528]
IL2 TTF89GD Definitive Biomarker [529]
IL7 TT8FRMO Definitive Biomarker [45]
IRF1 TT4TU3L Definitive Altered Expression [530]
KDR TTUTJGQ Definitive Posttranslational Modification [531]
KISS1 TTU2O6T Definitive Altered Expression [532]
LCN2 TTKTLAI Definitive Biomarker [512]
LDHA TTW76JE Definitive Biomarker [533]
LILRB1 TTC0QRJ Definitive Altered Expression [534]
LYVE1 TTG8DNU Definitive Biomarker [535]
MC1R TT0MV2T Definitive Altered Expression [536]
MIA TT5HNVS Definitive Biomarker [537]
MMP13 TTHY57M Definitive Altered Expression [538]
MMP7 TTMTWOS Definitive Altered Expression [539]
MTA1 TTO4HUS Definitive Biomarker [540]
MYCN TT9JBY5 Definitive Genetic Variation [541]
NGFR TTEDJN4 Definitive Altered Expression [542]
NPEPPS TT371QC Definitive Biomarker [543]
PEBP1 TT1BGU8 Definitive Biomarker [544]
PECAM1 TT4EZB2 Definitive Biomarker [545]
PGR TTUV8G9 Definitive Biomarker [546]
PIK3CB TT9H4P3 Definitive Biomarker [547]
POSTN TT8ALTZ Definitive Altered Expression [548]
PTGES TTYLQ8V Definitive Biomarker [549]
PTP4A3 TT7YM8D Definitive Biomarker [550]
S100A9 TT0TMQG Definitive Altered Expression [551]
SATB1 TTLFRIC Definitive Biomarker [552]
SELE TT1PL7M Definitive Biomarker [553]
SELP TTE5VG0 Definitive Altered Expression [203]
SF3B1 TTL2WUI Definitive Genetic Variation [554]
SLC5A5 TTW7HI9 Definitive Altered Expression [555]
SLC6A8 TTYUHB5 Definitive Biomarker [556]
TNFSF11 TT9E8HR Definitive Altered Expression [557]
TNK2 TTIET93 Definitive Biomarker [558]
TWIST1 TTX1MY7 Definitive Biomarker [559]
TYR TTULVH8 Definitive Biomarker [560]
USP5 TTGYTMA Definitive Genetic Variation [561]
ZEB2 TTT2WK4 Definitive Altered Expression [562]
------------------------------------------------------------------------------------
⏷ Show the Full List of 595 DTT(s)
This Disease Is Related to 9 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
SLC2A3 DT9SQ3L Limited Biomarker [563]
SLC39A14 DTZ6IJW Limited Altered Expression [564]
ATP7A DT0LT17 moderate Biomarker [565]
ABCB6 DTF9Y2V Strong Altered Expression [566]
SLC26A2 DTFSLX5 Strong Altered Expression [567]
SLC39A4 DTEZCUM Strong Biomarker [568]
SLC4A7 DT03V27 Strong Altered Expression [569]
SLC4A9 DTSQY0W Strong Biomarker [570]
SLC52A1 DT7NOKR Strong Altered Expression [571]
------------------------------------------------------------------------------------
⏷ Show the Full List of 9 DTP(s)
This Disease Is Related to 27 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
DHRS3 DEXPVUN Limited Altered Expression [572]
GLDC DEIN8FB Limited Biomarker [559]
HPRT1 DEVXTP5 Limited Altered Expression [573]
HSD3B1 DERDQWN Limited Genetic Variation [574]
LAP3 DENZF0O Limited Biomarker [575]
MT1A DE5ME8A Limited Biomarker [576]
UGDH DE48Q2Z Limited Biomarker [577]
UGT2B15 DENZ6B1 Limited Biomarker [578]
ACP3 DEDW5H6 moderate Biomarker [579]
CHST3 DEQIZP2 moderate Genetic Variation [580]
CYP27B1 DE3FYEM moderate Altered Expression [581]
WARS1 DEPVE0M moderate Altered Expression [582]
AKR1C1 DE7P2FB Strong Biomarker [583]
CMPK1 DEMPH4I Strong Biomarker [584]
DIO3 DET89OV Strong Biomarker [275]
HPGD DEHKSC6 Strong Biomarker [585]
HSD17B10 DEGSPC9 Strong Altered Expression [586]
NT5C DE4E31Z Strong Biomarker [587]
PLPP1 DE6WXTH Strong Altered Expression [588]
PTGDS DER3H9C Strong Altered Expression [445]
SI DE5EO4Y Strong Biomarker [589]
TPMT DEFQ8VO Strong Biomarker [590]
UGT1A7 DEZO4N3 Strong Genetic Variation [591]
UGT2B17 DEAZDL8 Strong Biomarker [592]
UPP2 DEBQ2WU Strong Altered Expression [593]
CYB5R3 DE4A3BL Definitive Altered Expression [594]
PSAT1 DEBS17P Definitive Biomarker [543]
------------------------------------------------------------------------------------
⏷ Show the Full List of 27 DME(s)
This Disease Is Related to 968 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
ACTR3 OT05LJSH Limited Biomarker [595]
AEBP1 OTBI1RZ6 Limited Altered Expression [596]
AGO1 OTD3R434 Limited Altered Expression [597]
AHNAK2 OTD2X4BX Limited Altered Expression [598]
ALDH6A1 OT8LCZCT Limited Biomarker [528]
ALPP OTZU4G9W Limited Biomarker [11]
AMFR OTQRX7LC Limited Biomarker [308]
ANXA3 OTDD8OI7 Limited Altered Expression [599]
APOBEC3A OTYO6F5P Limited Biomarker [595]
APOBEC3B OTHLNI51 Limited Altered Expression [600]
ARHGEF7 OT9BPJCL Limited Biomarker [601]
ARL2BP OT7REEDA Limited Altered Expression [602]
ARPC2 OTSOKOMY Limited Biomarker [603]
ASAP1 OT4DLRYY Limited Biomarker [193]
ATP2C2 OTGIHTYQ Limited Biomarker [604]
ATP6V0C OTKPL09B Limited Biomarker [605]
AXIN1 OTRGZGZ5 Limited Biomarker [41]
BAG1 OTRQNIA4 Limited Altered Expression [606]
BCORL1 OTPTFQN5 Limited Biomarker [607]
CACYBP OTJMZD2T Limited Biomarker [608]
CADM4 OT0TFMFE Limited Altered Expression [609]
CAP2 OTC1WFNO Limited Altered Expression [610]
CARMIL3 OT4ZN0K3 Limited Altered Expression [611]
CBX4 OT4XVRRF Limited Altered Expression [612]
CCN4 OT69BER9 Limited Biomarker [613]
CD226 OT4UG0KB Limited Biomarker [20]
CD99 OTPUZ5DE Limited Biomarker [614]
CETN1 OTGQ8JOZ Limited Altered Expression [615]
CHAC1 OTJGE772 Limited Altered Expression [616]
CHD1 OT9R9G0H Limited Altered Expression [617]
CLDN1 OT27KV99 Limited Biomarker [618]
CLDN2 OTRF3D6Y Limited Altered Expression [619]
CLDN5 OTUX60YO Limited Altered Expression [620]
CLDN7 OTNE0XHQ Limited Altered Expression [621]
CLEC4G OTUGTR0H Limited Biomarker [622]
CMTM8 OTG28GH2 Limited Altered Expression [623]
COPS3 OTZWPJ24 Limited Altered Expression [624]
CRABP2 OTY01V9G Limited Genetic Variation [625]
CSH1 OT33HTRR Limited Biomarker [626]
CSH2 OTW8JVAN Limited Biomarker [626]
CST1 OTE4I83Q Limited Altered Expression [627]
CST6 OTZVHJTF Limited Altered Expression [628]
CSTA OT1K68KE Limited Altered Expression [629]
CTAG1B OTIQGW6U Limited Biomarker [26]
CXCL14 OTM189TA Limited Altered Expression [630]
CYFIP1 OTOBEH24 Limited Altered Expression [631]
CYP4Z1 OTKRGJBG Limited Biomarker [632]
CYREN OT5ZL00R Limited Biomarker [633]
CYRIB OTLRN4L1 Limited Biomarker [634]
CYTL1 OTLYUPUY Limited Biomarker [635]
DACH1 OTMKNAGG Limited Altered Expression [636]
DCX OTISR7K3 Limited Biomarker [637]
DEF6 OTIRBYVK Limited Altered Expression [488]
DIAPH1 OTZBYPLH Limited Biomarker [638]
DUSP2 OTH54FMR Limited Altered Expression [639]
DVL1 OTD67RF1 Limited Altered Expression [640]
DVL3 OTPRROHJ Limited Altered Expression [640]
EIF6 OTEXMUED Limited Altered Expression [641]
EPS8 OTZ6ES6V Limited Altered Expression [642]
ERRFI1 OT7VZ2IZ Limited Altered Expression [643]
EYA1 OTHU807A Limited Biomarker [644]
FAM83A OTBI16V7 Limited Altered Expression [645]
FARP2 OTNRQIMK Limited Biomarker [646]
FASTK OTTHFZMP Limited Biomarker [647]
FAT4 OT7QONNV Limited Altered Expression [648]
FBLN1 OT5MHHOP Limited Biomarker [649]
FBXW5 OT5TQK3H Limited Altered Expression [650]
FDCSP OT8KGE9M Limited Altered Expression [651]
FGF13 OTHNNVSG Limited Biomarker [652]
FGF9 OT2SKDGM Limited Biomarker [653]
FLI1 OT0EV3LX Limited Biomarker [654]
FOXL2 OTFRQUYL Limited Biomarker [336]
FSTL1 OT6KEZUD Limited Biomarker [655]
FUT7 OTJF6BSN Limited Biomarker [656]
FUT8 OTJJCVG1 Limited Biomarker [657]
FZD6 OTBCPII8 Limited Altered Expression [658]
GASK1B OT2HPHEI Limited Biomarker [659]
GGPS1 OTVEHG28 Limited Altered Expression [660]
GLUD1 OTXKOCUH Limited Biomarker [15]
GNLY OTZJKA8C Limited Altered Expression [73]
GPAA1 OTWVRR35 Limited Altered Expression [661]
GPRC5A OTPOCWR7 Limited Altered Expression [662]
H2AZ1 OT3KJJNQ Limited Altered Expression [663]
H3-3B OT9XHQ3C Limited Genetic Variation [664]
HECTD1 OTJ95JJS Limited Altered Expression [665]
HHIP OT77RQYS Limited Biomarker [666]
HHLA2 OTYBTVQS Limited Altered Expression [667]
HIPK1 OTSEA8RS Limited Biomarker [668]
HIPK3 OT4WYQM2 Limited Altered Expression [669]
HLA-DOA OTZE5Q7R Limited Biomarker [670]
HNRNPM OTFU3OEZ Limited Biomarker [671]
HOXB8 OTKHOD17 Limited Biomarker [672]
ICAM3 OTTZ5A5D Limited Biomarker [46]
IL10RA OTOX3D1D Limited Altered Expression [673]
IL20RA OTSIVBVS Limited Altered Expression [332]
INSRR OT3F75WA Limited Genetic Variation [674]
IRF7 OTC1A2PQ Limited Altered Expression [675]
ISL1 OTVNVKAX Limited Biomarker [676]
JAG1 OT3LGT6K Limited Altered Expression [677]
KANK2 OT3SZIWM Limited Biomarker [608]
KDM4B OT5P1UPY Limited Altered Expression [678]
KIF18A OTSMBJ24 Limited Biomarker [679]
KLF10 OT4F4UGS Limited Biomarker [680]
KLF12 OTVH4KD4 Limited Altered Expression [681]
KLF8 OTUC5CDB Limited Altered Expression [682]
LAMA4 OTHI7TA0 Limited Altered Expression [683]
LDOC1 OTWZH4O9 Limited Biomarker [684]
LIN28B OTVWP0FN Limited Biomarker [685]
LOXL1 OTA0NEJU Limited Biomarker [686]
LOXL3 OTLLY1QI Limited Biomarker [686]
LPXN OTUNV3CK Limited Biomarker [106]
LRIG1 OTY5HZN5 Limited Biomarker [687]
LRRC8A OT23OE7H Limited Altered Expression [688]
MAGT1 OTQSAV5C Limited Biomarker [11]
MAP1LC3B OTUYHB84 Limited Biomarker [689]
MARCHF1 OTI2EYO6 Limited Genetic Variation [690]
MARCHF8 OTH7PNN2 Limited Biomarker [691]
MB OTYWYL2D Limited Biomarker [692]
MED1 OTOO24C4 Limited Altered Expression [693]
MFF OTEVIXOM Limited Altered Expression [694]
MFSD2A OTVG1VG0 Limited Altered Expression [695]
MGAT3 OTXI5X4T Limited Biomarker [696]
MLLT10 OTURMDV7 Limited Biomarker [697]
MLXIP OT30UNI7 Limited Biomarker [691]
MLXIPL OTR9MLLW Limited Biomarker [698]
MMRN1 OT7ZNYHT Limited Biomarker [699]
MOCOS OT0TL3Q5 Limited Biomarker [700]
MPEG1 OT7DAO0F Limited Biomarker [701]
MRI1 OTOP49DM Limited Biomarker [633]
MTA2 OTCCYIQJ Limited Altered Expression [702]
MTMR2 OTNCYGBP Limited Altered Expression [703]
MUC13 OTWKS9MF Limited Biomarker [704]
MYLIP OTL0PFGV Limited Biomarker [691]
MYOCD OTSJNHTH Limited Altered Expression [705]
MYOD1 OTV2S79X Limited Genetic Variation [706]
NANS OTMQ2FUH Limited Genetic Variation [707]
NCR3LG1 OT15YWU7 Limited Altered Expression [708]
NCS1 OT6JHAWM Limited Biomarker [709]
NFIB OTX94PD0 Limited Biomarker [710]
NMU OTW9X7BQ Limited Altered Expression [711]
NPNT OTFZAO1G Limited Biomarker [712]
NUPR1 OT4FU8C0 Limited Biomarker [713]
OCIAD2 OTSWB4SZ Limited Biomarker [714]
PBOV1 OT67PERT Limited Altered Expression [715]
PBXIP1 OTEAAUBY Limited Biomarker [716]
PIP OTH719AH Limited Biomarker [717]
PIWIL3 OTQ1B8R4 Limited Altered Expression [718]
PKD1 OT5ALRZ5 Limited Altered Expression [719]
PLOD3 OTT00T7Q Limited Biomarker [720]
PLXND1 OTNK9ALK Limited Altered Expression [721]
POU2F1 OTK7ELJ0 Limited Altered Expression [78]
PSMD14 OTJWHMZ5 Limited Biomarker [722]
PTCHD3 OTFQ1VGM Limited Biomarker [723]
PTOV1 OT94WT5X Limited Biomarker [724]
PTPRM OTCEL6PN Limited Altered Expression [725]
PUF60 OTG90DYF Limited Biomarker [646]
RAB27B OTPF9D0K Limited Biomarker [726]
RAP1GAP OTC31ONQ Limited Biomarker [727]
RASGRP3 OTEMEV3P Limited Altered Expression [728]
RBBP8 OTRHJ3GI Limited Biomarker [713]
RBM14 OTO9GMBD Limited Biomarker [608]
RHBDD1 OTL5J132 Limited Biomarker [729]
RHOC OTOLE1FT Limited Altered Expression [730]
RPL36A OT1LYV85 Limited Altered Expression [643]
RPLP1 OT7B0SIB Limited Biomarker [731]
SDF4 OTQ7WFYW Limited Altered Expression [615]
SEC23A OTBRNIJ3 Limited Biomarker [732]
SEMA3D OTD5TJV1 Limited Biomarker [733]
SEMA4A OT8901H3 Limited Biomarker [734]
SESN2 OT889IXY Limited Biomarker [735]
SHROOM2 OTZ2FJ7Q Limited Biomarker [736]
SIRT7 OT5M4OT4 Limited Altered Expression [737]
SMCP OTXKY794 Limited Biomarker [700]
SND1 OTT734JN Limited Altered Expression [738]
SNPH OTL6XBFA Limited Altered Expression [739]
SORBS1 OTWH8762 Limited Biomarker [740]
SOX17 OT9H4WWE Limited Biomarker [741]
SOX18 OTPUMHWA Limited Biomarker [742]
SPRTN OT01D5CE Limited Genetic Variation [743]
SRF OTW18FQN Limited Altered Expression [705]
SRI OT4R3EAC Limited Altered Expression [744]
STIP1 OT7TXLOX Limited Biomarker [745]
STK3 OTLNSCQD Limited Biomarker [746]
SYNM OTOI8TRJ Limited Biomarker [37]
TBX2 OTTOT7A9 Limited Altered Expression [628]
TCEA1 OTBFO594 Limited Biomarker [608]
TENM3 OTWY13GR Limited Biomarker [596]
TFIP11 OT7NVSWU Limited Biomarker [747]
TGIF1 OTN9VHAG Limited Biomarker [748]
TJP1 OTBDCUPK Limited Biomarker [51]
TMED9 OTYGAQS0 Limited Biomarker [319]
TMEM41A OTAAULKY Limited Biomarker [749]
TMSB10 OTLVZ13T Limited Altered Expression [750]
TNFAIP1 OT37EWR0 Limited Biomarker [751]
TNFSF9 OTV9L89D Limited Biomarker [752]
TOPORS OT1ERFFQ Limited Biomarker [753]
TRAF2 OT1MEZZN Limited Biomarker [754]
TRAPPC9 OTF0CVMC Limited Altered Expression [488]
TRIM31 OT7VW6RP Limited Biomarker [755]
TRIM44 OT0B1T2B Limited Altered Expression [756]
TRIM72 OTFAFXPC Limited Altered Expression [757]
TSACC OT3QW6PH Limited Biomarker [608]
TSPAN31 OT8WQ83R Limited Genetic Variation [707]
TTC4 OTAPMYXU Limited Genetic Variation [758]
ATXN7 OTL3YF1H Disputed Biomarker [759]
AZIN2 OT8OB7CG Disputed Biomarker [760]
C16orf82 OT77Z5Y5 Disputed Biomarker [761]
CABIN1 OT4G5CIK Disputed Biomarker [762]
CADM2 OT45PVKC Disputed Biomarker [763]
CASP8AP2 OTTWT68S Disputed Biomarker [764]
CD200R1 OT65Q9M6 Disputed Altered Expression [765]
CD2AP OTC76KQM Disputed Biomarker [766]
CDC45 OT6NNLOD Disputed Biomarker [767]
CDCA5 OTZLCQ5U Disputed Biomarker [767]
CLIP1 OTTGAEJE Disputed Altered Expression [768]
CMTM7 OTI7Q2JW Disputed Altered Expression [769]
COL15A1 OTTFKK18 Disputed Altered Expression [768]
COL5A1 OT24078H Disputed Altered Expression [770]
DPT OTINRFC7 Disputed Biomarker [106]
EFNA1 OTU2NUA2 Disputed Altered Expression [771]
ETV4 OT8C98UZ Disputed Altered Expression [16]
FBN2 OT3KYJQL Disputed Biomarker [772]
GADL1 OTJM4A0R Disputed Biomarker [760]
GAGE7 OTF8BTR9 Disputed Biomarker [773]
HM13 OTGEO1LP Disputed Altered Expression [774]
HUWE1 OTFH6BJS Disputed Biomarker [775]
IFI16 OT4SPU0U Disputed Altered Expression [776]
IMMP1L OTA6LOLR Disputed Altered Expression [774]
IQGAP2 OTX2UA7P Disputed Altered Expression [777]
MADD OTUFYVGG Disputed Biomarker [778]
MAGEH1 OTVE05K7 Disputed Altered Expression [768]
MAP2K4 OTZPZX11 Disputed Biomarker [779]
MEST OT8Q4U8Y Disputed Biomarker [780]
MUC4 OTLT11V1 Disputed Biomarker [781]
OPCML OT93PQ6Y Disputed Altered Expression [782]
OPN3 OTON6BFU Disputed Altered Expression [783]
PARP10 OTILI1DU Disputed Biomarker [784]
PDCD5 OT6T2DDL Disputed Biomarker [785]
POLE OTFM3MMU Disputed Biomarker [786]
PPP1CB OTYFTYFR Disputed Biomarker [775]
PRSS3 OTN3S5YB Disputed Altered Expression [787]
SAG OTDNS3ZQ Disputed Altered Expression [788]
SBSN OT89RKJH Disputed Altered Expression [789]
SMR3B OTL5HNM8 Disputed Altered Expression [414]
TFPI2 OTZCRWOR Disputed Altered Expression [790]
TRAM1 OT3I0H8E Disputed Biomarker [106]
AADAC OT8VACT2 moderate Altered Expression [177]
ADAM12 OTZKOTDB moderate Altered Expression [791]
ADGRG1 OTQBB8NT moderate Altered Expression [792]
AGFG1 OTI8ZKC4 moderate Biomarker [793]
ALX1 OTZVARA5 moderate Altered Expression [794]
ANXA4 OTUCRYXL moderate Altered Expression [795]
AQP5 OT77GBY8 moderate Altered Expression [796]
ASPM OTKXQMNA moderate Altered Expression [797]
ATF2 OTNIZPEA moderate Altered Expression [798]
ATG4A OTDHXAPG moderate Biomarker [799]
AXIN2 OTRMGQNU moderate Altered Expression [800]
BMS1 OTEGQ8ZO moderate Biomarker [801]
BNIP3 OT4SO7J4 moderate Altered Expression [155]
BUD23 OTJS7VU3 moderate Biomarker [802]
CALU OTSYQN71 moderate Biomarker [649]
CANX OTYP1F6J moderate Biomarker [197]
CAPN3 OTCHG3YK moderate Altered Expression [803]
CARD10 OT2RPM4I moderate Altered Expression [804]
CBFA2T3 OTOJ10S1 moderate Altered Expression [805]
CBX8 OT4U5V1T moderate Biomarker [806]
CCDC8 OTO295IH moderate Biomarker [197]
CCDC88A OT3SSYYC moderate Altered Expression [807]
CD81 OTQFXNAZ moderate Biomarker [808]
CDH9 OTV9N5XK moderate Biomarker [809]
CEMIP OTK80FYN moderate Biomarker [810]
CFL1 OTT6D5MH moderate Altered Expression [811]
CKLF OTHLPHA0 moderate Biomarker [812]
CMTM3 OTS75IGC moderate Biomarker [813]
COL11A1 OTB0DRMS moderate Biomarker [770]
CTBP1 OTVYH2DH moderate Biomarker [814]
CTHRC1 OTV88X2G moderate Biomarker [815]
CTNND1 OTUMPSHR moderate Altered Expression [816]
CUL4A OTTBV70J moderate Altered Expression [817]
CYC1 OT0962IM moderate Altered Expression [818]
CYLD OT37FKH0 moderate Genetic Variation [819]
DEGS1 OT4WXPKW moderate Biomarker [820]
DERL2 OTI3TUUZ moderate Biomarker [821]
DLC1 OTP8LMCR moderate Biomarker [822]
DLX2 OTKC2DQ0 moderate Genetic Variation [179]
DNM3 OTDMUGCR moderate Altered Expression [823]
DUSP4 OT6WAO12 moderate Altered Expression [824]
ECD OT3L3PCU moderate Biomarker [825]
ECM1 OT1K65VW moderate Biomarker [826]
ECRG4 OTHZYUXX moderate Biomarker [827]
ECT2 OTQDUCT6 moderate Altered Expression [828]
EMP1 OTSZHUHQ moderate Biomarker [829]
EMP2 OTPS2H0L moderate Altered Expression [830]
ENO2 OTRODL0T moderate Biomarker [831]
ESRP1 OTNCS4SL moderate Altered Expression [832]
ETV1 OT6PMJIK moderate Altered Expression [833]
FAM3C OTBR6U9G moderate Altered Expression [834]
FANCC OTTIDM3P moderate Genetic Variation [835]
FBP1 OTQBANEP moderate Altered Expression [836]
FBXO32 OTUE978R moderate Biomarker [837]
FBXO4 OT6VYX67 moderate Biomarker [838]
FBXW4 OTEGSZOX moderate Altered Expression [177]
FKBP14 OT55W5WC moderate Altered Expression [839]
FLNB OTPCOYL6 moderate Biomarker [840]
FOXF2 OTV20NGX moderate Altered Expression [841]
FOXK1 OTLZGS7J moderate Biomarker [842]
FOXO4 OT90X9LN moderate Biomarker [843]
FZD1 OTZATHVS moderate Biomarker [844]
FZD2 OT952ML1 moderate Biomarker [845]
FZD5 OTXFFY56 moderate Biomarker [844]
G3BP2 OTAWW3KI moderate Biomarker [846]
GALNT14 OT9BSDDQ moderate Biomarker [847]
GDF1 OTZ1VRBH moderate Biomarker [848]
GFPT1 OTQBDO45 moderate Biomarker [849]
GOLM1 OTOZSV6O moderate Biomarker [850]
GPC2 OT3WSQE1 moderate Biomarker [851]
GRB14 OTFET2YM moderate Altered Expression [852]
GSTM3 OTLA2WJT moderate Biomarker [853]
HOXA9 OTKNK5H0 moderate Biomarker [854]
ICMT OT8CNKBO moderate Biomarker [793]
IFIT3 OTPGHZB9 moderate Altered Expression [855]
IFITM3 OT2QP8D3 moderate Altered Expression [856]
IL17RB OT0KDNSF moderate Altered Expression [857]
IL1RAPL1 OTW3T4B2 moderate Biomarker [858]
ING1 OTEZBRKW moderate Genetic Variation [859]
ING4 OT0VVG4V moderate Biomarker [860]
INPP4B OTLROA7G moderate Altered Expression [861]
INSM1 OTG8RV8E moderate Biomarker [862]
IQGAP1 OTZRWTGA moderate Biomarker [303]
IRF2 OTAZRUW3 moderate Biomarker [863]
KAT2A OTN0W2SW moderate Genetic Variation [864]
KAT8 OT5LPQTR moderate Biomarker [865]
KLF17 OT5NWVP7 moderate Biomarker [866]
KLRD1 OTMYLOV4 moderate Altered Expression [867]
KRT14 OTUVZ1DW moderate Altered Expression [868]
KRT7 OTLT3JFN moderate Altered Expression [869]
LAD1 OT6YGTVX moderate Biomarker [870]
LATS1 OTOOCG4R moderate Posttranslational Modification [871]
LEF1 OTWS5I5H moderate Altered Expression [872]
LUM OTSRC874 moderate Altered Expression [643]
MAGEB6 OTOTV1FU moderate Genetic Variation [55]
MAGI1 OTMV4ASV moderate Biomarker [873]
MAPK6 OTDDNF3Q moderate Biomarker [169]
METTL14 OT6TPQMH moderate Biomarker [874]
MIEN1 OTCQ8DAD moderate Altered Expression [875]
MIIP OT79EXZ7 moderate Biomarker [876]
MMUT OTBBBV70 moderate Biomarker [877]
MOK OTQK7M9V moderate Biomarker [878]
MSC OTBRPZL5 moderate Biomarker [879]
MST1 OTOC4UNG moderate Altered Expression [746]
MVP OTJGHJRB moderate Altered Expression [880]
MYBBP1A OTIVEMIU moderate Biomarker [881]
MYOF OTRFC3IJ moderate Biomarker [882]
NAB2 OTG4BDF3 moderate Biomarker [883]
NCOR1 OT04XNOU moderate Biomarker [884]
NID2 OTHC33FF moderate Biomarker [885]
NOB1 OTW0YNSL moderate Biomarker [886]
NR2C2 OTDZWVOJ moderate Biomarker [168]
NXF1 OTEFHXG6 moderate Biomarker [840]
OCM OTQRML29 moderate Biomarker [887]
OTUB1 OT8WWM9O moderate Altered Expression [888]
PARD3 OTH5BPLO moderate Biomarker [137]
PDLIM5 OTLQVV22 moderate Biomarker [889]
PEAK1 OTVVM637 moderate Altered Expression [890]
PFN1 OTHTGA1H moderate Biomarker [891]
PIK3C2B OTY2PROB moderate Altered Expression [892]
PITPNA OTTWC00K moderate Biomarker [893]
PLAAT3 OTVXXJ5K moderate Biomarker [894]
PLAGL1 OTZAO900 moderate Altered Expression [895]
PLK3 OT19CT2Z moderate Altered Expression [896]
PLXNA1 OTN0BING moderate Altered Expression [897]
PMEPA1 OTY8Z9UF moderate Biomarker [898]
PNPLA2 OTR3ERMR moderate Biomarker [104]
PODXL OTPNQXF3 moderate Biomarker [899]
POLD1 OTWO4UCJ moderate Altered Expression [900]
POLH OTN07WXU moderate Altered Expression [901]
POLK OTKZ38JH moderate Altered Expression [901]
POU2F2 OTPV0J0C moderate Biomarker [902]
POU3F3 OT6BBXPD moderate Altered Expression [903]
PPP1R13L OTNCPLWE moderate Biomarker [848]
PPP2R1A OTYA3GB4 moderate Genetic Variation [904]
PPP4C OT4B0TNV moderate Biomarker [905]
PPRC1 OT6GB3WR moderate Biomarker [906]
PRDX1 OTZ3BEC4 moderate Altered Expression [907]
PRUNE1 OTQ3UHWQ moderate Biomarker [908]
PTPRF OTH5KF2D moderate Genetic Variation [909]
PXN OTVMMUOF moderate Posttranslational Modification [910]
RAB27A OT9SQRWY moderate Biomarker [726]
RAB37 OTRL8IUO moderate Biomarker [911]
RAB3D OTGKRR3C moderate Biomarker [912]
RANBP9 OTM8COM5 moderate Altered Expression [913]
RASSF6 OT25GVWY moderate Biomarker [914]
RBM5 OTCBWHHV moderate Biomarker [915]
RCC2 OTUJVTLS moderate Biomarker [916]
RMC1 OT7K8MTJ moderate Altered Expression [917]
RND3 OTXMXPIH moderate Altered Expression [918]
RNH1 OT6EC79B moderate Biomarker [848]
RPL10 OTBHOZGC moderate Altered Expression [897]
RPS15A OT0BUA12 moderate Altered Expression [919]
RSPO2 OT3HHXU0 moderate Altered Expression [920]
S100A10 OTI71243 moderate Altered Expression [155]
S100A13 OT582SUS moderate Altered Expression [921]
SALL4 OTC08PR5 moderate Altered Expression [922]
SDCBP OTS3NCC5 moderate Biomarker [923]
SDHC OTC8G2MX moderate Biomarker [924]
SEMA3F OTQFMS8S moderate Biomarker [925]
SEMA7A OT0ZJK64 moderate Genetic Variation [926]
SH3BGRL OTUOCTMT moderate Biomarker [927]
SHC3 OT305NPA moderate Biomarker [848]
SIRT4 OT5S0J23 moderate Altered Expression [928]
SIX1 OT70YYWM moderate Biomarker [636]
SMC1A OT9ZMRK9 moderate Altered Expression [929]
SMOC2 OTK1EQ49 moderate Biomarker [930]
SMS OT8JYKNH moderate Biomarker [931]
SOCS2 OTBPNKJQ moderate Biomarker [932]
SOHLH2 OTB9EM6C moderate Biomarker [933]
SPANXB1 OTLMGC9T moderate Biomarker [934]
SPRY2 OTH0CRCZ moderate Biomarker [935]
SRGAP2 OTUWFMCQ moderate Biomarker [936]
SS18L1 OT9ZEGV7 moderate Genetic Variation [937]
ST6GAL1 OT7US3NO moderate Biomarker [938]
STUB1 OTSUYI9A moderate Biomarker [939]
SUZ12 OT655XF8 moderate Altered Expression [940]
TBPL1 OT4I143E moderate Altered Expression [209]
TET1 OTZDHT1D moderate Posttranslational Modification [941]
TGFBI OTR443C5 moderate Biomarker [942]
THBS2 OTXET551 moderate Biomarker [943]
TLE5 OTEH0BFG moderate Altered Expression [944]
TMEM52B OTOC70IF moderate Altered Expression [945]
TNNT1 OT8PBOAR moderate Biomarker [761]
TOMM20 OT76TPR2 moderate Biomarker [946]
TOPBP1 OT6UPZPD moderate Genetic Variation [947]
TPD52 OTPKSK43 moderate Biomarker [948]
TPM1 OTD73X6R moderate Altered Expression [949]
TRIM16 OTLRXYOZ moderate Altered Expression [950]
TRIM25 OT35SG1R moderate Biomarker [951]
TRIM3 OT704FQ0 moderate Biomarker [952]
TRIM62 OT15YO6N moderate Biomarker [953]
TSPAN2 OTTDPQF1 moderate Biomarker [954]
TSPAN9 OT3DI3NH moderate Altered Expression [955]
A1CF OTJBKFA1 Strong Genetic Variation [229]
A2M OTFTX90K Strong Altered Expression [956]
ABHD14B OTFIYC6Y Strong Altered Expression [957]
ABI1 OT5H4M62 Strong Altered Expression [958]
ABI3 OTQTDSHP Strong Biomarker [959]
ACTG2 OTRDWUO0 Strong Biomarker [960]
ACTR1B OTGBCKLO Strong Biomarker [354]
ADAM23 OTVWT6JZ Strong Altered Expression [961]
ADAM28 OT3GBVHL Strong Altered Expression [9]
ADAMTS2 OTTK22NO Strong Biomarker [962]
ADCY10 OTYSTB0R Strong Altered Expression [314]
ADGRE2 OTUYJVYG Strong Genetic Variation [963]
ADGRE5 OTTSB84Q Strong Genetic Variation [963]
ADGRF3 OTR8JBEW Strong Altered Expression [218]
AGR3 OTONJPDP Strong Genetic Variation [964]
AHNAK OT6KH1WG Strong Biomarker [965]
AIMP1 OTTA5C3U Strong Altered Expression [966]
ALDH3A1 OTAYZZE6 Strong Altered Expression [88]
ALKBH1 OTADGU5D Strong Altered Expression [967]
AMBP OTLU8GU8 Strong Altered Expression [968]
AMOTL2 OTRCTKV9 Strong Altered Expression [293]
ANGPT4 OT881M3K Strong Biomarker [969]
ANGPTL1 OTXIN6V5 Strong Biomarker [969]
ANGPTL2 OTB6JG41 Strong Biomarker [970]
ANKHD1 OTVYQ7ZL Strong Biomarker [971]
ANKRD30A OTJXYAE5 Strong Biomarker [972]
AP5Z1 OTXIPLFH Strong Biomarker [973]
APLP1 OTD176ZS Strong Altered Expression [974]
APLP2 OTTFE53M Strong Biomarker [975]
ARF6 OTVV7KJO Strong Biomarker [976]
ARHGAP24 OTCQCEZS Strong Altered Expression [768]
ARHGEF4 OTR2VG0W Strong Biomarker [976]
ARID4B OTYLPILE Strong Biomarker [977]
ARL6IP5 OTYZ6BEQ Strong Biomarker [978]
ARNT OTMSIEZY Strong Biomarker [979]
ARR3 OTRZ00CH Strong Biomarker [385]
ARSF OTC0L12N Strong Altered Expression [980]
ARTN OTWIWGL6 Strong Biomarker [981]
ATN1 OTNZFLKY Strong Altered Expression [553]
ATRX OT77RSQW Strong Genetic Variation [436]
B4GALNT1 OTCY80HS Strong Altered Expression [982]
BAMBI OTCEJ8W5 Strong Altered Expression [983]
BANP OT1JMTBD Strong Biomarker [984]
BATF2 OT4XBZC9 Strong Altered Expression [985]
BCAR1 OTKT2C2N Strong Altered Expression [986]
BCL2L12 OTS6IFZY Strong Altered Expression [987]
BHLHE22 OTZUQY5L Strong Biomarker [988]
BLM OTEJOAJX Strong Biomarker [340]
BOK OTDQPDIX Strong Altered Expression [989]
BRMS1 OTV5A6LL Strong Altered Expression [990]
BRMS1L OTJIW47U Strong Biomarker [991]
BTF3 OT5ZZFJL Strong Biomarker [992]
BTG2 OTZF6K1H Strong Biomarker [354]
BTRC OT2EZDGR Strong Altered Expression [993]
BUB1B OT8KME51 Strong Biomarker [994]
BUD31 OTN3HZYF Strong Altered Expression [995]
CALB2 OTSNMCG9 Strong Biomarker [996]
CALD1 OTNJKJ6Q Strong Altered Expression [997]
CAMKMT OTLJBRUW Strong Altered Expression [998]
CBLL2 OTB4AD3V Strong Biomarker [308]
CBX1 OT2L4XZX Strong Biomarker [999]
CCL15 OTOGZ85M Strong Biomarker [1000]
CCL18 OT7JYSK9 Strong Altered Expression [1001]
CCL19 OTQ2UJMH Strong Posttranslational Modification [1002]
CCL28 OTY6XNQ7 Strong Altered Expression [309]
CCN3 OTOW5YL4 Strong Altered Expression [897]
CCN5 OTADU8JJ Strong Altered Expression [1003]
CCNY OTK1KG5W Strong Altered Expression [1004]
CD177 OTS79FNF Strong Biomarker [1005]
CD302 OTX580VU Strong Altered Expression [1006]
CD3D OTRBLP0R Strong Biomarker [1007]
CD63 OT2UGZA9 Strong Altered Expression [1008]
CD68 OTOYEY3J Strong Biomarker [1009]
CDC42 OT5QBC5M Strong Biomarker [558]
CDCP1 OTD7RRWK Strong Biomarker [1010]
CDH17 OT9EV2XK Strong Biomarker [1011]
CDKN3 OTBE3H07 Strong Biomarker [1012]
CDSN OTQW4HV6 Strong Biomarker [1013]
CEBPD OTNBIPMY Strong Altered Expression [1014]
CETN2 OTJTTGS0 Strong Biomarker [1015]
CFAP20 OTIG8TR5 Strong Biomarker [1016]
CHAF1A OTXSSY4H Strong Altered Expression [1017]
CHD1L OT7CZK7C Strong Biomarker [1018]
CHD4 OTBDEHDP Strong Biomarker [1019]
CHD8 OTS7A6AF Strong Genetic Variation [436]
CHI3L1 OT2Z7VJH Strong Biomarker [1020]
CKAP4 OTDUC9ME Strong Biomarker [426]
CKS1B OTNUPLUJ Strong Biomarker [1021]
CKS2 OTPTMHIV Strong Altered Expression [1022]
CLCA2 OTF191LZ Strong Biomarker [411]
CLCN4 OT4A2UWF Strong Biomarker [1023]
CLDN3 OT71MN9S Strong Biomarker [1024]
CLEC1B OTO38TRG Strong Altered Expression [1025]
COMP OTS2FPMI Strong Biomarker [1026]
CORO1C OTXDF9T3 Strong Altered Expression [1027]
COTL1 OT6YCNLF Strong Biomarker [1028]
CPEB4 OTW1SCZW Strong Altered Expression [1029]
CREM OTJIJ5AL Strong Biomarker [1030]
CRIP1 OT0EICG3 Strong Altered Expression [1031]
CRISP3 OTBSWMPL Strong Altered Expression [1032]
CRKL OTOYSD1R Strong Biomarker [1033]
CTNNBIP1 OTX9SBJG Strong Genetic Variation [1034]
CTR9 OTP151PZ Strong Altered Expression [1017]
CTSO OTFL6VRO Strong Biomarker [962]
CTTN OTJRG4ES Strong Altered Expression [1035]
CXADR OT9ZP02A Strong Biomarker [385]
CXCL16 OTD49T9R Strong Biomarker [1036]
CXCL17 OTRCEVIZ Strong Altered Expression [1037]
CXCL5 OTZOUPCA Strong Biomarker [1038]
CXCL6 OTFTCQ4O Strong Biomarker [1039]
DAB2IP OTF456VC Strong Biomarker [1040]
DACT1 OT19Z704 Strong Posttranslational Modification [1041]
DAP OT5YLL7E Strong Genetic Variation [1042]
DAXX OTX6O7PL Strong Genetic Variation [436]
DCLRE1C OTW3KB1I Strong Biomarker [1043]
DCTN6 OTI8PIN9 Strong Biomarker [1044]
DCUN1D1 OT8UJLZU Strong Altered Expression [1045]
DDX3X OTDO4TRX Strong Biomarker [1046]
DDX53 OTHK3EGZ Strong Biomarker [1047]
DDX6 OTKWXVDY Strong Biomarker [1048]
DEPDC5 OTE70JLY Strong Genetic Variation [436]
DERL3 OTRZRT6Q Strong Genetic Variation [463]
DGCR2 OTEGL17Z Strong Altered Expression [1049]
DKK4 OTWCCVF6 Strong Altered Expression [1050]
DLD OT378CU9 Strong Biomarker [1051]
DLEC1 OTMKKBUW Strong Altered Expression [1052]
DLX6 OT0FIJHY Strong Altered Expression [1053]
DNAJA3 OT61924T Strong Biomarker [1054]
DNAJB4 OTUD01BK Strong Altered Expression [1055]
DNER OT2GH2E5 Strong Biomarker [1056]
DNLZ OT48CG1W Strong Biomarker [1057]
DPYSL3 OTINJV20 Strong Biomarker [1058]
DRAM2 OTBOCZH8 Strong Altered Expression [1059]
DRG1 OTIFYMI3 Strong Altered Expression [1060]
DSC2 OTODVH8K Strong Biomarker [1061]
DSP OTB2MOP8 Strong Altered Expression [1062]
DSPP OT1TYNDN Strong Biomarker [1063]
DYNLL1 OTR69LHT Strong Altered Expression [1052]
EFS OT06O7XL Strong Posttranslational Modification [1064]
EGR3 OTGPJIRA Strong Biomarker [1065]
EIF1AX OTWG2LAB Strong Biomarker [1066]
EIF3A OTFABY9G Strong Altered Expression [1067]
EIF3H OT61RBF5 Strong Altered Expression [1068]
EIF3I OTE07WND Strong Altered Expression [1069]
EIF4A2 OT08H03R Strong Biomarker [1070]
EIF4G1 OT2CF1E6 Strong Biomarker [1070]
ELP1 OTYEWBF7 Strong Altered Expression [1017]
EPB41L3 OTS6CHG2 Strong Biomarker [1071]
ERCC1 OTNPYQHI Strong Altered Expression [1072]
ERCC5 OTQAKFJM Strong Genetic Variation [1073]
ESAM OTF518AI Strong Biomarker [1074]
ESCO2 OTJEMAQU Strong Biomarker [1075]
ETV5 OTE2OBM4 Strong Biomarker [1076]
EWSR1 OT7SRHV3 Strong Biomarker [1077]
EXOC7 OT4YA137 Strong Biomarker [1078]
FABP7 OTRE2H4G Strong Altered Expression [1079]
FAIM2 OT6QINVO Strong Biomarker [1080]
FAM210B OT2QHEQ6 Strong Biomarker [1081]
FAT2 OTRGT3E8 Strong Genetic Variation [1082]
FBLIM1 OTFHXMON Strong Biomarker [1083]
FBLN5 OTLVNZ8U Strong Altered Expression [1084]
FGF17 OTAQSFZ2 Strong Altered Expression [1085]
FGF3 OT9PK2SI Strong Altered Expression [1086]
FHL2 OT0OAYWT Strong Altered Expression [682]
FMNL2 OT9OVWCV Strong Altered Expression [1087]
FNBP1L OTH1S2P2 Strong Biomarker [1088]
FNDC3B OTBILGDR Strong Altered Expression [1089]
FOXA1 OTEBY0TD Strong Altered Expression [302]
FOXA2 OTJOCVOY Strong Biomarker [1090]
FOXF1 OT2CJZ5K Strong Altered Expression [1091]
FOXG1 OTAW57J4 Strong Biomarker [1092]
FOXO3 OTHXQG4P Strong Biomarker [1093]
FSD1 OT8P6PT3 Strong Altered Expression [1094]
FSD1L OTBQ48RF Strong Altered Expression [1094]
FSIP1 OTYLL6GM Strong Biomarker [1095]
FUCA1 OTW71IK4 Strong Altered Expression [1096]
FZD8 OTZ9IRFL Strong Biomarker [1097]
GALNT5 OTCV61V1 Strong Biomarker [1098]
GEMIN2 OT4L6TLL Strong Biomarker [1099]
GNA12 OT3IRZH3 Strong Biomarker [1100]
GNB3 OTA6HYBA Strong Genetic Variation [1101]
GOLGA4 OTCMEHNJ Strong Biomarker [1039]
GOPC OTRBGH71 Strong Biomarker [1083]
GORASP1 OTQS91S7 Strong Biomarker [1102]
GPAT3 OTJUGPK0 Strong Biomarker [1103]
GPC6 OTNJBESF Strong Biomarker [1104]
GPR160 OTMXJT73 Strong Biomarker [309]
GPR42 OTEB0ROY Strong Biomarker [14]
GPR68 OT1NXSMN Strong Biomarker [1105]
GPX3 OT6PK94R Strong Altered Expression [155]
GRB7 OTF8Y9XY Strong Altered Expression [1106]
GRP OT8JDFNI Strong Biomarker [1107]
GTF2I OTUYL1TQ Strong Biomarker [1108]
GTF2IRD1 OTEG9KU1 Strong Biomarker [1108]
GTPBP4 OT6ZHAWC Strong Biomarker [1109]
HAS1 OTJIAG1W Strong Altered Expression [1110]
HAS2 OTTD3PAL Strong Altered Expression [1110]
HAS3 OTPM8IL8 Strong Altered Expression [1110]
HAVCR2 OTOL603T Strong Biomarker [670]
HERPUD1 OT9EROL6 Strong Altered Expression [1111]
HES6 OTWO5SCF Strong Altered Expression [1112]
HEYL OTN7BH79 Strong Altered Expression [1113]
HINT2 OTW9GS0U Strong Altered Expression [1114]
HIP1 OT7AKCFQ Strong Biomarker [1115]
HLA-DRB3 OT5PM9N7 Strong Genetic Variation [1116]
HLA-E OTX1CTFB Strong Biomarker [73]
HLTF OTRX2OSF Strong Altered Expression [1045]
HMMR OT4M0JTZ Strong Biomarker [1117]
HNRNPK OTNPRM8U Strong Biomarker [1118]
HOXB7 OTC7WYU8 Strong Biomarker [1098]
HOXD8 OTJ5H7AT Strong Altered Expression [1119]
HPSE2 OTGEPP8V Strong Biomarker [1120]
HSD17B6 OTSB55D2 Strong Altered Expression [586]
HSPB2 OTS01646 Strong Biomarker [528]
HTRA3 OTXJ0H4X Strong Biomarker [1121]
HUNK OTZR4GBH Strong Altered Expression [1122]
HYAL2 OTTVINXW Strong Altered Expression [1110]
HYAL3 OTG6VUSP Strong Altered Expression [1110]
IBSP OT29944Y Strong Biomarker [1123]
ID3 OTUULW5Z Strong Biomarker [328]
IFI27 OTI2XGIT Strong Biomarker [1044]
IGF2BP1 OT9G360P Strong Altered Expression [1124]
IGF2BP3 OTB97VIK Strong Biomarker [976]
IL2RG OTRZ3OMY Strong Biomarker [1125]
INA OT1D33T4 Strong Altered Expression [1126]
IQSEC1 OTK1PBFD Strong Biomarker [1127]
ITGA2B OT4Y17PY Strong Biomarker [1128]
ITGA3 OTBCH21D Strong Biomarker [1129]
ITGA7 OTTBTAYW Strong Biomarker [962]
ITGB4 OT28UK84 Strong Biomarker [1130]
ITIH5 OTP46PZM Strong Genetic Variation [1131]
JARID2 OT14UM8H Strong Altered Expression [1132]
JDP2 OTW35WKX Strong Biomarker [1133]
KAZN OTPM7BYM Strong Altered Expression [1134]
KDM2B OTDMCVW7 Strong Altered Expression [1135]
KDM4D OTN6KAE6 Strong Biomarker [1136]
KIF5B OTT34MT8 Strong Biomarker [1137]
KIFC1 OTNQDS00 Strong Altered Expression [1138]
KLF11 OTKVQDJD Strong Genetic Variation [1139]
KLF9 OTBFEJRQ Strong Altered Expression [1140]
KRIT1 OT58AP1I Strong Altered Expression [998]
KRT13 OTTYSKGX Strong Altered Expression [1141]
KRT18 OTVLQFIP Strong Biomarker [1142]
KRT8 OTTM4X11 Strong Biomarker [1143]
LACTB OTRWGNBF Strong Biomarker [1144]
LAMP3 OTN0XL3W Strong Biomarker [1145]
LAT OTZC1XZ1 Strong Altered Expression [1146]
LDHB OT9B1CT3 Strong Altered Expression [1147]
LGALS3BP OT9AGQKH Strong Biomarker [1148]
LGI1 OTPS77HO Strong Altered Expression [1149]
LIMA1 OTONPC9R Strong Biomarker [1150]
LMCD1 OT3AWE8O Strong Genetic Variation [1151]
LMO4 OT5NDCT9 Strong Altered Expression [1091]
LORICRIN OTFRPVEO Strong Biomarker [1152]
LOXL4 OT6XY2JL Strong Biomarker [1153]
LRPAP1 OT6DVD2Q Strong Biomarker [1154]
LSAMP OTYXVQX2 Strong Biomarker [1145]
LTO1 OTQ17ZDT Strong Biomarker [1155]
LYPD5 OTGP7UKA Strong Biomarker [540]
LZTFL1 OTIEIOEW Strong Altered Expression [1156]
MAGEC3 OT0KDWZN Strong Altered Expression [314]
MAGED2 OTMEWNSE Strong Biomarker [1157]
MAGED4B OTO37U7W Strong Biomarker [360]
MAL2 OTVPEI80 Strong Biomarker [1158]
MAP1B OTVXW089 Strong Biomarker [1159]
MARCKSL1 OT13J2FM Strong Biomarker [1160]
MBD2 OTUQPP0R Strong Altered Expression [1161]
MCAT OTH07FIW Strong Altered Expression [265]
MCRS1 OT8K2X8P Strong Altered Expression [1162]
MCTS1 OT7SAOJP Strong Altered Expression [265]
MDC1 OTEUQH4J Strong Biomarker [1163]
MED19 OTT9RT5N Strong Biomarker [1164]
MED23 OTKZQT0R Strong Altered Expression [1165]
METTL3 OTSXP1M3 Strong Biomarker [1166]
MGAT5 OTU4DD4G Strong Altered Expression [1167]
MGP OTZWU3FU Strong Biomarker [1168]
MIB1 OT5C404P Strong Biomarker [1169]
MIP OTEBLU3E Strong Altered Expression [1170]
MLLT11 OTG5RVHC Strong Biomarker [1171]
MMP28 OTHQZXM1 Strong Biomarker [1172]
MMRN2 OT4IRL0U Strong Altered Expression [1173]
MRPL40 OTB2QZDY Strong Altered Expression [1174]
MSH3 OTD3YPVL Strong Altered Expression [1175]
MT1E OTXJKU4Y Strong Posttranslational Modification [1176]
MT1H OT0MVBM6 Strong Altered Expression [1177]
MTMR3 OTBIT23O Strong Biomarker [396]
MTSS1 OT5DTDO2 Strong Altered Expression [1178]
MUC2 OT3X4QVX Strong Altered Expression [1179]
MUL1 OT2JC9YR Strong Biomarker [308]
MYBL2 OTZ3JX8Q Strong Altered Expression [1180]
MYCL OT1MFQ5U Strong Biomarker [1181]
MYH11 OTVNVWY3 Strong Genetic Variation [1134]
MYH9 OT94Z706 Strong Genetic Variation [1182]
MYO1C OT69L39Y Strong Altered Expression [1183]
MYO1E OTM9YSIZ Strong Altered Expression [1183]
MYOM2 OTD2UOXW Strong Genetic Variation [1184]
NANOG OTUEY1FM Strong Biomarker [1185]
NAP1L1 OTI7WBZV Strong Biomarker [1157]
ND6 OTG47B7B Strong Genetic Variation [1186]
NDRG1 OTVO66BO Strong Biomarker [1187]
NDRG2 OT5L6KD7 Strong Altered Expression [1188]
NECTIN1 OTTE5ZR6 Strong Biomarker [1189]
NEDD4L OT1B19RU Strong Altered Expression [1190]
NEU1 OTH9BY8Y Strong Biomarker [1191]
NEURL1 OT2C4P70 Strong Biomarker [1191]
NEUROG1 OTMJZP9G Strong Altered Expression [1192]
NFAT5 OTKIE59S Strong Altered Expression [615]
NFATC2 OTK5T6HZ Strong Altered Expression [1193]
NIBAN1 OTYOLI12 Strong Biomarker [963]
NKX2-1 OTCMEJTA Strong Genetic Variation [1194]
NKX2-2 OTDCOYNG Strong Biomarker [1195]
NLK OT2LETFS Strong Posttranslational Modification [1196]
NME2 OTCYGLHV Strong Biomarker [1197]
NNAT OTNRLO7G Strong Altered Expression [1198]
NOC2L OTNT7R33 Strong Biomarker [1199]
NONO OTN36Q6U Strong Altered Expression [1200]
NPC1 OTRIPICX Strong Biomarker [1201]
NSD2 OTQ6SW4R Strong Altered Expression [1202]
NTN4 OTDRRMP3 Strong Biomarker [1203]
NUBPL OTQMCSXT Strong Biomarker [1204]
OCLN OTSUTVWL Strong Altered Expression [1205]
OLIG2 OTMCN6D3 Strong Altered Expression [1206]
ONECUT1 OTK1QUQT Strong Altered Expression [1207]
OPN1MW OTPJ7LX4 Strong Genetic Variation [1208]
OPRPN OT6K1ZD6 Strong Altered Expression [413]
OR51E1 OTB7Q65H Strong Biomarker [1209]
ORM2 OTRJGZP8 Strong Biomarker [264]
OSBP OT7R0OQQ Strong Altered Expression [1210]
PADI2 OTT40K94 Strong Altered Expression [1211]
PAEP OTQA0NV4 Strong Biomarker [1212]
PAFAH1B1 OT9T2TCJ Strong Biomarker [1213]
PANX1 OTXPEDOK Strong Biomarker [1214]
PAX2 OTKP1N8F Strong Biomarker [1215]
PAX8 OTRPD9MI Strong Biomarker [1216]
PBX3 OT8WMVM4 Strong Altered Expression [1217]
PCBP1 OTHN0TD7 Strong Biomarker [1218]
PCGF2 OTIY1J5L Strong Altered Expression [1219]
PDLIM1 OT4EGCPG Strong Biomarker [1220]
PEA15 OTKCKTSX Strong Biomarker [1221]
PELP1 OTVXQNOT Strong Altered Expression [1222]
PERP OTP0YL53 Strong Biomarker [1223]
PFKFB4 OTQYEXL2 Strong Biomarker [1224]
PFN2 OT5SSSA7 Strong Altered Expression [1225]
PGK1 OT6V1ICH Strong Altered Expression [1226]
PHGR1 OTY3GTEP Strong Altered Expression [1227]
PHLDA1 OTFTWMIQ Strong Altered Expression [1228]
PIGR OT6GLSUL Strong Biomarker [1229]
PIK3R4 OTRL8QP8 Strong Altered Expression [1017]
PIWIL1 OT7CRGZ3 Strong Biomarker [1230]
PIWIL4 OTDA9MY0 Strong Biomarker [1230]
PLPP5 OTHT51D6 Strong Genetic Variation [1231]
PLRG1 OTIVZ5LL Strong Altered Expression [413]
PLXNB1 OTCA7JIT Strong Genetic Variation [1232]
POT1 OTNBXJCQ Strong Altered Expression [1233]
POU3F2 OT30NFOC Strong Biomarker [1234]
POU3F4 OTKF5AF7 Strong Genetic Variation [1235]
POU5F1 OTDHHN7O Strong Altered Expression [1236]
PPA1 OTHZK1QB Strong Altered Expression [1237]
PPP1R14C OTZ3F6D2 Strong Altered Expression [1238]
PPP1R1A OTGTAGCV Strong Biomarker [467]
PPP1R9B OTDCTHTT Strong Altered Expression [1239]
PPWD1 OTA7CG42 Strong Altered Expression [1006]
PRDM1 OTQLSVBS Strong Biomarker [1240]
PRDM2 OT8L7CGX Strong Biomarker [1241]
PRKAA2 OTU1KZPV Strong Biomarker [15]
PROK1 OT8S7RUG Strong Biomarker [399]
PROX1 OT68R6IO Strong Altered Expression [1242]
PRUNE2 OTGW2974 Strong Altered Expression [1243]
PSMA5 OT38E6Y1 Strong Biomarker [973]
PSMD4 OTH1VZTM Strong Altered Expression [980]
PSMD9 OT6Y5CC3 Strong Biomarker [1044]
PTPRT OTV5TXNN Strong Biomarker [1244]
PTRH2 OTBU39Q1 Strong Biomarker [1245]
PTTG1 OTIMYS4W Strong Altered Expression [1246]
PTX3 OTPXHRKU Strong Altered Expression [1247]
PVR OT3N91T7 Strong Altered Expression [1248]
RAB11FIP3 OTDFFCZA Strong Altered Expression [1249]
RAB11FIP4 OTIGHER7 Strong Altered Expression [1250]
RAB17 OT7NBUGQ Strong Biomarker [1251]
RAB23 OTBAKFBR Strong Altered Expression [1252]
RAB31 OTMLXQZ0 Strong Biomarker [1253]
RAB38 OTU0NZU0 Strong Biomarker [1254]
RAB3GAP2 OTQTE0GI Strong Altered Expression [1017]
RAB5A OTFR2KM4 Strong Altered Expression [1255]
RAB8A OTPB54Y3 Strong Biomarker [1256]
RABGEF1 OTWC3Z3R Strong Altered Expression [1255]
RAG2 OTG9UYTW Strong Biomarker [1125]
RANBP1 OTQE226K Strong Altered Expression [1257]
RASD1 OT2BAJHK Strong Genetic Variation [1258]
RASGRF1 OTNWJ7EN Strong Altered Expression [1255]
RASGRF2 OT67DAGF Strong Biomarker [1259]
RB1CC1 OTZK8PFX Strong Altered Expression [1260]
RBM47 OT6W67VM Strong Altered Expression [1261]
RCAN1 OT1MVXC7 Strong Biomarker [1262]
RCOR3 OT5LATME Strong Altered Expression [1263]
RETREG1 OTYOSLZX Strong Biomarker [1264]
RGS19 OTBIELDO Strong Biomarker [1265]
RGS22 OTCTFGW6 Strong Altered Expression [1266]
RGS5 OTUY0Q2I Strong Altered Expression [1267]
RHBDF1 OTCQ7UDS Strong Altered Expression [1268]
RNF111 OTO3QT6Q Strong Biomarker [1269]
ROPN1L OTRWZJ68 Strong Genetic Variation [229]
RTL1 OTOT33IM Strong Biomarker [368]
RUNX1T1 OT30DED5 Strong Altered Expression [1270]
S100A1 OT1F2G4J Strong Biomarker [1271]
S100A2 OTTGHJ1H Strong Posttranslational Modification [1272]
S100A7 OTJFVJRF Strong Biomarker [1273]
SATB2 OT2W80XC Strong Biomarker [1274]
SCAF11 OTX59D0X Strong Biomarker [1099]
SCARA5 OTOVA96E Strong Altered Expression [986]
SCGB2A1 OT9L87U9 Strong Biomarker [1275]
SCTR OTC80IMR Strong Biomarker [1276]
SDC3 OT1P0LJM Strong Biomarker [1244]
SEC14L2 OTJST64D Strong Biomarker [840]
SEMA3E OTD4S36H Strong Biomarker [721]
SENP2 OTPQJXIR Strong Biomarker [1277]
SEPTIN9 OT1VMRFQ Strong Biomarker [1278]
SERPINE2 OTYF5340 Strong Biomarker [92]
SFRP1 OT0U9G41 Strong Biomarker [1279]
SH3GL2 OTOE443G Strong Biomarker [1280]
SH3GLB2 OTF7BB9S Strong Altered Expression [1281]
SIM1 OTYKFPKZ Strong Genetic Variation [1139]
SIPA1 OTXY5RXC Strong Genetic Variation [1282]
SLC16A4 OT1YXBKC Strong Altered Expression [265]
SLC2A4RG OTW3LX8D Strong Altered Expression [1255]
SLC46A3 OTEMDLPS Strong Altered Expression [1283]
SLURP1 OT89YD2E Strong Biomarker [1284]
SMAD2 OTC6VB4K Strong Altered Expression [1202]
SMAGP OT57BZII Strong Altered Expression [1285]
SMARCE1 OTAX4ITH Strong Altered Expression [1286]
SMG1 OTTS3SXE Strong Altered Expression [281]
SNAI2 OT7Y8EJ2 Strong Altered Expression [1287]
SNED1 OTBQVXY5 Strong Altered Expression [1288]
SNTA1 OTUICTGZ Strong Biomarker [962]
SOX10 OTF25ULQ Strong Biomarker [1289]
SOX4 OTSS40SS Strong Altered Expression [1290]
SOX9 OTVDJFGN Strong Altered Expression [1236]
SP7 OT07ETZT Strong Biomarker [1291]
SPAM1 OTMPOB4E Strong Biomarker [1292]
SPARCL1 OT74DWMV Strong Biomarker [1293]
SPATA19 OT47CHQR Strong Altered Expression [1281]
SPG7 OT8OY9ST Strong Biomarker [385]
SPINK7 OTK3VOI3 Strong Altered Expression [1294]
SPON2 OTE7JLNM Strong Biomarker [1295]
SPRED2 OTUX685J Strong Biomarker [1166]
SPRR2A OT62ZU6B Strong Biomarker [1296]
SPSB3 OTHGEE2K Strong Altered Expression [1297]
SPZ1 OTQH8HJ5 Strong Biomarker [1298]
SRSF1 OTF61HOV Strong Altered Expression [980]
SRSF5 OTC5WP98 Strong Biomarker [1299]
SRSF6 OTGLOSYE Strong Altered Expression [1300]
SS18 OTDKHN1E Strong Genetic Variation [1301]
SSX1 OTZ7NRCY Strong Genetic Variation [1301]
SSX2 OT2Z6RLL Strong Biomarker [1302]
STAT5A OTBSJGN3 Strong Altered Expression [1303]
STAT5B OTZVPEBT Strong Altered Expression [1303]
STIM1 OT8CLQ1W Strong Biomarker [1304]
STK11 OT1YZSP3 Strong Altered Expression [1305]
STON2 OT01JHHE Strong Biomarker [1306]
SYNJ2BP OT2Q677P Strong Biomarker [1307]
SYP OTFJKMO4 Strong Biomarker [37]
SYT1 OTVTPOI6 Strong Biomarker [1102]
TAB3 OT1ECMDL Strong Altered Expression [1308]
TAPBP OTL81AVZ Strong Genetic Variation [1309]
TBC1D9 OTSSCTB5 Strong Genetic Variation [1310]
TBX1 OTQLBPRA Strong Biomarker [1311]
TCIM OTARUXQF Strong Altered Expression [1312]
TEX11 OTJDBGSS Strong Biomarker [1313]
TFF3 OTJJDRTU Strong Biomarker [1314]
THAP11 OTEMWLZ0 Strong Altered Expression [1315]
TICAM2 OTK7GIJ5 Strong Biomarker [1044]
TIMP1 OTOXC51H Strong Altered Expression [371]
TIMP3 OTDGQAD1 Strong Biomarker [1316]
TM4SF5 OTPAV531 Strong Biomarker [1317]
TM7SF2 OTILU5S7 Strong Altered Expression [1318]
TMED3 OTNOPHHC Strong Biomarker [1319]
TMED7 OTONO8E6 Strong Biomarker [1044]
TMEM106A OTHTBYDN Strong Posttranslational Modification [1320]
TMEM176A OTOZDWXX Strong Posttranslational Modification [1321]
TMEM8B OTJZWPS6 Strong Biomarker [1322]
TNFRSF10C OTVHOL9B Strong Altered Expression [1323]
TNFRSF6B OTKAN9G7 Strong Altered Expression [1324]
TOX3 OTC9NR4W Strong Biomarker [88]
TP53BP2 OTOWJ2Y4 Strong Altered Expression [1325]
TP53INP1 OT2363Z9 Strong Biomarker [1326]
TP73 OT0LUO47 Strong Altered Expression [768]
TPPP3 OTU8VUIG Strong Biomarker [1327]
TRAF4 OTJLRVMC Strong Altered Expression [1328]
TRAIP OTMPT9Y2 Strong Altered Expression [1045]
TRAP1 OTNG0L8J Strong Altered Expression [1329]
TRIB3 OTG5OS7X Strong Altered Expression [1330]
TRIM13 OTQIUACB Strong Biomarker [385]
TRIM2 OT0V1YVC Strong Biomarker [1331]
TRIM65 OTSQTK3A Strong Altered Expression [1332]
TRIT1 OTCU9FS5 Strong Altered Expression [1333]
TSPAN8 OT1F68WQ Strong Biomarker [1334]
TTF1 OT4K90WD Strong Biomarker [1335]
ACTB OT1MCP2F Definitive Biomarker [1336]
API5 OTYX9YCZ Definitive Biomarker [510]
ATG5 OT4T5SMS Definitive Altered Expression [1337]
ATL1 OTR2788Y Definitive Altered Expression [504]
BCL6B OT1T5KM6 Definitive Biomarker [1338]
BMPR1A OTQOA4ZH Definitive Biomarker [1339]
CDR2 OTD3ZJST Definitive Genetic Variation [1340]
CERS2 OTRAHYYP Definitive Biomarker [1341]
CMPK2 OTOG90R0 Definitive Altered Expression [1342]
DDX49 OT13VWB7 Definitive Biomarker [1343]
ELF3 OTUTLEQO Definitive Biomarker [1344]
EPB41L5 OTPPQPLU Definitive Biomarker [1345]
ERG OTOTX9VU Definitive Biomarker [617]
GNA13 OTVDL515 Definitive Altered Expression [1346]
HJURP OTWMV16B Definitive Biomarker [1347]
HSPA4 OT5HR0AR Definitive Biomarker [775]
KRT20 OT4RB40L Definitive Biomarker [1348]
MACC1 OTV3DLX0 Definitive Genetic Variation [1349]
MYO7A OTBZSPEL Definitive Biomarker [1350]
PDC OT1UUVYY Definitive Biomarker [1351]
PDPN OTBUV19I Definitive Altered Expression [1352]
PLAG1 OTT9AJQY Definitive Biomarker [543]
PLIN5 OTV8G50L Definitive Biomarker [1009]
POFUT1 OTOBJZIT Definitive Biomarker [1353]
PROS1 OTXQWNOI Definitive Biomarker [543]
PTHLH OTI1JF13 Definitive Biomarker [1354]
RAMP2 OTGQXLH5 Definitive Biomarker [1355]
RAMP3 OTX6XLLM Definitive Biomarker [1355]
RNF2 OTFPLOIN Definitive Biomarker [1356]
SNAI1 OTDPYAMC Definitive Biomarker [1357]
TIMM8A OTDX9687 Definitive Biomarker [1358]
------------------------------------------------------------------------------------
⏷ Show the Full List of 968 DOT(s)

References

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2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1835).
3 ClinicalTrials.gov (NCT02923349) A Phase 1/2, Open-Label, Dose-Escalation, Safety Study of INCAGN01949 in Subjects With Advanced or Metastatic Solid Tumors. U.S. National Institutes of Health.
4 A phase I trial of intratumoral administration of recombinant oncolytic adenovirus overexpressing HSP70 in advanced solid tumor patients. Gene Ther. 2009 Mar;16(3):376-82.
5 ClinicalTrials.gov (NCT03696030) HER2-CAR T Cells in Treating Participants With Brain or Leptomeningeal Metastases
6 ClinicalTrials.gov (NCT02414269) Malignant Pleural Disease Treated With Autologous T Cells Genetically Engineered to Target the Cancer-Cell Surface Antigen Mesothelin
7 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
8 Depletion of Lipid Efflux Pump ABCG1 Triggers the Intracellular Accumulation of Extracellular Vesicles and Reduces Aggregation and Tumorigenesis of Metastatic Cancer Cells.Front Oncol. 2018 Oct 10;8:376. doi: 10.3389/fonc.2018.00376. eCollection 2018.
9 Adamalysines as Biomarkers and a Potential Target of Therapy in Colorectal Cancer Patients: Preliminary Results.Dis Markers. 2019 Sep 2;2019:5035234. doi: 10.1155/2019/5035234. eCollection 2019.
10 ADAMTS5 acts as a tumor suppressor by inhibiting migration, invasion and angiogenesis in human gastric cancer.Gastric Cancer. 2019 Mar;22(2):287-301. doi: 10.1007/s10120-018-0866-2. Epub 2018 Aug 13.
11 Immunostimulating and cancer-reductive experimental therapy with the oxazaphosphorine cytostatic SUM-IAP.Anticancer Drugs. 2018 Jun;29(5):411-415. doi: 10.1097/CAD.0000000000000608.
12 Asparaginase-like protein 1 is an independent prognostic marker in primary endometrial cancer, and is frequently lost in metastatic lesions.Gynecol Oncol. 2018 Jan;148(1):197-203. doi: 10.1016/j.ygyno.2017.10.025. Epub 2017 Oct 31.
13 An analysis of a multiple biomarker panel to better predict prostate cancer metastasis after radical prostatectomy.Int J Cancer. 2019 Mar 1;144(5):1151-1159. doi: 10.1002/ijc.31906. Epub 2018 Dec 4.
14 Quantitative phosphoproteomic analysis reveals system-wide signaling pathways downstream of SDF-1/CXCR4 in breast cancer stem cells.Proc Natl Acad Sci U S A. 2014 May 27;111(21):E2182-90. doi: 10.1073/pnas.1404943111. Epub 2014 Apr 29.
15 The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer.Mol Cell. 2018 Jan 4;69(1):87-99.e7. doi: 10.1016/j.molcel.2017.11.025. Epub 2017 Dec 14.
16 CIC-DUX4 oncoprotein drives sarcoma metastasis and tumorigenesis via distinct regulatory programs.J Clin Invest. 2019 Jul 22;129(8):3401-3406. doi: 10.1172/JCI126366. eCollection 2019 Jul 22.
17 CCR4 is a determinant of melanoma brain metastasis.Oncotarget. 2017 May 9;8(19):31079-31091. doi: 10.18632/oncotarget.16076.
18 CCR5 status and metastatic progression in colorectal cancer.Oncoimmunology. 2019 Jul 13;8(9):e1626193. doi: 10.1080/2162402X.2019.1626193. eCollection 2019.
19 Selective targeting of collagen IV in the cancer cell microenvironment reduces tumor burden.Oncotarget. 2018 Jan 19;9(13):11020-11045. doi: 10.18632/oncotarget.24280. eCollection 2018 Feb 16.
20 DNAM-1 and the TIGIT/PVRIG/TACTILE Axis: Novel Immune Checkpoints for Natural Killer Cell-Based Cancer Immunotherapy.Cancers (Basel). 2019 Jun 23;11(6):877. doi: 10.3390/cancers11060877.
21 CDC20 associated with cancer metastasis and novel mushroomderived CDC20 inhibitors with antimetastatic activity.Int J Oncol. 2019 Jun;54(6):2250-2256. doi: 10.3892/ijo.2019.4791. Epub 2019 Apr 18.
22 Pan-Cancer Analysis of the Mediator Complex Transcriptome Identifies CDK19 and CDK8 as Therapeutic Targets in Advanced Prostate Cancer.Clin Cancer Res. 2017 Apr 1;23(7):1829-1840. doi: 10.1158/1078-0432.CCR-16-0094. Epub 2016 Sep 27.
23 Carboxypeptidase E-N promotes migration, invasiveness, and epithelial-mesenchymal transition of human osteosarcoma cells via the Wnt--catenin pathway.Biochem Cell Biol. 2019 Aug;97(4):446-453. doi: 10.1139/bcb-2018-0236. Epub 2018 Dec 3.
24 Balanced Steady-State Free Precession Sequence (CISS/FIESTA/3D Driven Equilibrium Radiofrequency Reset Pulse) Increases the Diagnostic Yield for Spinal Drop Metastases in Children with Brain Tumors.AJNR Am J Neuroradiol. 2018 Jul;39(7):1355-1361. doi: 10.3174/ajnr.A5645. Epub 2018 May 17.
25 Sex-dependent correlation between survival and expression of genes related to the circadian oscillator in patients with colorectal cancer.Chronobiol Int. 2018 Sep;35(10):1423-1434. doi: 10.1080/07420528.2018.1488722. Epub 2018 Jun 28.
26 Immune targets and neoantigens for cancer immunotherapy and precision medicine.Cell Res. 2017 Jan;27(1):11-37. doi: 10.1038/cr.2016.155. Epub 2016 Dec 27.
27 Targeting CTCFL/BORIS for the immunotherapy of cancer. Cancer Immunol Immunother. 2018 Dec;67(12):1955-1965.
28 Gut microbiota-stimulated cathepsin K secretion mediates TLR4-dependent M2 macrophage polarization and promotes tumor metastasis in colorectal cancer.Cell Death Differ. 2019 Nov;26(11):2447-2463. doi: 10.1038/s41418-019-0312-y. Epub 2019 Mar 8.
29 Prognostic role of XTP1/DEPDC1B and SDP35/DEPDC1A in high grade soft-tissue sarcomas.Histol Histopathol. 2018 Jun;33(6):597-608. doi: 10.14670/HH-11-959. Epub 2018 Jan 3.
30 MDA-7/IL-24 regulates the miRNA processing enzyme DICER through downregulation of MITF.Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5687-5692. doi: 10.1073/pnas.1819869116. Epub 2019 Mar 6.
31 Tumor-secreted dickkopf2 accelerates aerobic glycolysis and promotes angiogenesis in colorectal cancer.Theranostics. 2019 Jan 30;9(4):1001-1014. doi: 10.7150/thno.30056. eCollection 2019.
32 Eukaryotic elongation factor 2 kinase upregulates the expression of proteins implicated in cell migration and cancer cell metastasis.Int J Cancer. 2018 May 1;142(9):1865-1877. doi: 10.1002/ijc.31210. Epub 2017 Dec 27.
33 Factor XIIIA-expressing inflammatory monocytes promote lung squamous cancer through fibrin cross-linking.Nat Commun. 2018 May 18;9(1):1988. doi: 10.1038/s41467-018-04355-w.
34 Androgen and Estrogen Receptor Imaging in Metastatic Breast Cancer Patients as a Surrogate for Tissue Biopsies.J Nucl Med. 2017 Dec;58(12):1906-1912. doi: 10.2967/jnumed.117.193649. Epub 2017 Sep 14.
35 Use of Porphysomes to detect primary tumour, lymph node metastases, intra-abdominal metastases and as a tool for image-guided lymphadenectomy: proof of concept in endometrial cancer.Theranostics. 2019 Apr 13;9(9):2727-2738. doi: 10.7150/thno.31225. eCollection 2019.
36 Overexpression of FNDC1 in Gastric Cancer and its Prognostic Significance.J Cancer. 2018 Nov 13;9(24):4586-4595. doi: 10.7150/jca.27672. eCollection 2018.
37 Insulinoma-associated protein 1 expression in primary and metastatic neuroendocrine neoplasms of the gastrointestinal and pancreaticobiliary tracts.Histopathology. 2019 Oct;75(4):568-577. doi: 10.1111/his.13899. Epub 2019 Jul 29.
38 Cytoplasmic HAX1 Is an Independent Risk Factor for Breast Cancer Metastasis.J Oncol. 2019 Apr 10;2019:6375025. doi: 10.1155/2019/6375025. eCollection 2019.
39 The homeostasis-maintaining metabolites from bacterial stress response to bacteriophage infection suppress tumor metastasis.Oncogene. 2018 Oct;37(43):5766-5779. doi: 10.1038/s41388-018-0376-z. Epub 2018 Jun 20.
40 TGF-1 induces epigenetic silence of TIP30 to promote tumor metastasis in esophageal carcinoma.Oncotarget. 2015 Feb 10;6(4):2120-33. doi: 10.18632/oncotarget.2940.
41 5-hydroxytryptamine receptor (5-HT1DR) promotes colorectal cancer metastasis by regulating Axin1/-catenin/MMP-7 signaling pathway.Oncotarget. 2015 Sep 22;6(28):25975-87. doi: 10.18632/oncotarget.4543.
42 Antitumor Activity of BRAF Inhibitor and IFN Combination in BRAF-Mutant Melanoma.J Natl Cancer Inst. 2016 Feb 5;108(7):djv435. doi: 10.1093/jnci/djv435. Print 2016 Jul.
43 Tumor-recruited M2 macrophages promote gastric and breast cancer metastasis via M2 macrophage-secreted CHI3L1 protein.J Hematol Oncol. 2017 Feb 1;10(1):36. doi: 10.1186/s13045-017-0408-0.
44 Development of a novel class of interleukin-2 immunotherapies for metastatic cancer.Swiss Med Wkly. 2019 Jan 23;149:w14697. doi: 10.4414/smw.2019.14697. eCollection 2019 Jan 14.
45 Interleukin-7 Contributes to the Invasiveness of Prostate Cancer Cells by Promoting Epithelial-Mesenchymal Transition.Sci Rep. 2019 May 6;9(1):6917. doi: 10.1038/s41598-019-43294-4.
46 ICAM3 mediates tumor metastasis via a LFA-1-ICAM3-ERM dependent manner.Biochim Biophys Acta Mol Basis Dis. 2018 Aug;1864(8):2566-2578. doi: 10.1016/j.bbadis.2018.05.002. Epub 2018 May 3.
47 Collective cell migration and metastases induced by an epithelial-to-mesenchymal transition in Drosophila intestinal tumors.Nat Commun. 2019 May 24;10(1):2311. doi: 10.1038/s41467-019-10269-y.
48 Function and regulation of LAG3 on CD4(+)CD25(-) T cells in non-small cell lung cancer.Exp Cell Res. 2017 Nov 15;360(2):358-364. doi: 10.1016/j.yexcr.2017.09.026. Epub 2017 Sep 19.
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180 Neurotensin Receptor-1 Expression in Human Prostate Cancer: A Pilot Study on Primary Tumors and Lymph Node Metastases.Int J Mol Sci. 2019 Apr 7;20(7):1721. doi: 10.3390/ijms20071721.
181 Hypoxia-induced upregulation of Orai1 drives colon cancer invasiveness and angiogenesis.Eur J Pharmacol. 2018 Aug 5;832:1-10. doi: 10.1016/j.ejphar.2018.05.008. Epub 2018 May 9.
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189 Expression of Wip1 in kidney carcinoma and its correlation with tumor metastasis and clinical significance.Pathol Oncol Res. 2015 Jan;21(1):219-24. doi: 10.1007/s12253-014-9811-9. Epub 2014 Jun 28.
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198 Semaphorin 4D Promotes Skeletal Metastasis in Breast Cancer.PLoS One. 2016 Feb 24;11(2):e0150151. doi: 10.1371/journal.pone.0150151. eCollection 2016.
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208 Expression of Telomere Repeat Binding Factor 1 and TRF2 in Prostate Cancer and Correlation with Clinical Parameters.Biomed Res Int. 2017;2017:9764752. doi: 10.1155/2017/9764752. Epub 2017 Jul 20.
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397 Identification of differentially expressed genes in metastatic and non-metastatic nasopharyngeal carcinoma cells by suppression subtractive hybridization.Cell Oncol. 2005;27(4):215-23. doi: 10.1155/2005/108490.
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596 AEBP1 promotes epithelial-mesenchymal transition of gastric cancer cells by activating the NF-B pathway and predicts poor outcome of the patients.Sci Rep. 2018 Aug 10;8(1):11955. doi: 10.1038/s41598-018-29878-6.
597 Argonaute, Dicer, and Drosha are up-regulated along tumor progression in serous ovarian carcinoma.Hum Pathol. 2012 Nov;43(11):2062-9. doi: 10.1016/j.humpath.2012.02.016. Epub 2012 May 29.
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601 ARHGEF7 promotes metastasis of colorectal adenocarcinoma by regulating the motility of cancer cells.Int J Oncol. 2018 Nov;53(5):1980-1996. doi: 10.3892/ijo.2018.4535. Epub 2018 Aug 22.
602 Epstein-Barr virus-encoded microRNA BART1 induces tumour metastasis by regulating PTEN-dependent pathways in nasopharyngeal carcinoma.Nat Commun. 2015 Jul 2;6:7353. doi: 10.1038/ncomms8353.
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611 Capping Protein Regulator and Myosin 1 Linker 3 Is Required for Tumor Metastasis.Mol Cancer Res. 2020 Feb;18(2):240-252. doi: 10.1158/1541-7786.MCR-19-0722. Epub 2019 Nov 6.
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613 WNT1-inducible signaling pathway protein 1 (WISP1/CCN4) stimulates melanoma invasion and metastasis by promoting the epithelial-mesenchymal transition.J Biol Chem. 2019 Apr 5;294(14):5261-5280. doi: 10.1074/jbc.RA118.006122. Epub 2019 Feb 5.
614 p53 and -Catenin Expression Predict Poorer Prognosis in Patients With Anaplastic Large-Cell Lymphoma.Clin Lymphoma Myeloma Leuk. 2019 Jul;19(7):e385-e392. doi: 10.1016/j.clml.2019.03.030. Epub 2019 Apr 5.
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616 Higher expression of cation transport regulator-like protein 1 (CHAC1) predicts of poor outcomes in uveal melanoma (UM) patients.Int Ophthalmol. 2019 Dec;39(12):2825-2832. doi: 10.1007/s10792-019-01129-1. Epub 2019 Jun 3.
617 Prostatic adenocarcinoma CNS parenchymal and dural metastases: alterations in ERG, CHD1 and MAP3K7 expression.J Neurooncol. 2019 Apr;142(2):319-325. doi: 10.1007/s11060-019-03099-x. Epub 2019 Jan 17.
618 Lentiviral Vector Mediated Claudin1 Silencing Inhibits Epithelial to Mesenchymal Transition in Breast Cancer Cells.Viruses. 2015 Jun 10;7(6):2965-79. doi: 10.3390/v7062755.
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620 Effect of bevacizumab on the tight junction proteins of vascular endothelial cells.Am J Transl Res. 2019 Sep 15;11(9):5546-5559. eCollection 2019.
621 The impact of CLAUDIN-1 on follicular thyroid carcinoma aggressiveness.Endocr Relat Cancer. 2015 Oct;22(5):819-30. doi: 10.1530/ERC-14-0502. Epub 2015 Jul 28.
622 C-type lectins facilitate tumor metastasis.Oncol Lett. 2017 Jan;13(1):13-21. doi: 10.3892/ol.2016.5431. Epub 2016 Nov 24.
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624 Novel oncogene COPS3 interacts with Beclin1 and Raf-1 to regulate metastasis of osteosarcoma through autophagy.J Exp Clin Cancer Res. 2018 Jul 3;37(1):135. doi: 10.1186/s13046-018-0791-6.
625 CRABP-II enhances pancreatic cancer cell migration and invasion by stabilizing interleukin 8 expression.Oncotarget. 2016 Dec 26;8(32):52432-52444. doi: 10.18632/oncotarget.14194. eCollection 2017 Aug 8.
626 Breast carcinoma in pregnancy with spheroid-like placental metastases-a case report.APMIS. 2018 May;126(5):448-452. doi: 10.1111/apm.12827. Epub 2018 Apr 17.
627 Cystatin SN inhibits auranofin-induced cell death by autophagic induction and ROS regulation via glutathione reductase activity in colorectal cancer.Cell Death Dis. 2017 Mar 16;8(3):e2682. doi: 10.1038/cddis.2017.100.
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629 Primary tumour expression of the cysteine cathepsin inhibitor Stefin A inhibits distant metastasis in breast cancer.J Pathol. 2008 Feb;214(3):337-46. doi: 10.1002/path.2265.
630 CXCL14, CXCR7 expression and CXCR4 splice variant ratio associate with survival and metastases in Ewing sarcoma patients.Eur J Cancer. 2015 Nov;51(17):2624-33. doi: 10.1016/j.ejca.2015.08.020. Epub 2015 Sep 28.
631 Low expression of Cyfip1 may be a potential biomarker in nasopharyngeal carcinoma.Neoplasma. 2018;65(2):292-295. doi: 10.4149/neo_2018_170318N194.
632 Efficient substrate screening and inhibitor testing of human CYP4Z1 using permeabilized recombinant fission yeast.Biochem Pharmacol. 2017 Dec 15;146:174-187. doi: 10.1016/j.bcp.2017.09.011. Epub 2017 Sep 23.
633 Changes in Brain Metastasis During Radiosurgical Planning.Int J Radiat Oncol Biol Phys. 2018 Nov 15;102(4):727-733. doi: 10.1016/j.ijrobp.2018.06.021. Epub 2018 Jun 25.
634 FAM49B, a novel regulator of mitochondrial function and integrity that suppresses tumor metastasis.Oncogene. 2018 Feb 8;37(6):697-709. doi: 10.1038/onc.2017.358. Epub 2017 Oct 23.
635 CYTL1 inhibits tumor metastasis with decreasing STAT3 phosphorylation.Oncoimmunology. 2019 Feb 18;8(5):e1577126. doi: 10.1080/2162402X.2019.1577126. eCollection 2019.
636 Dachshund 1 is Differentially Expressed Between Male and Female Breast Cancer: A Matched Case-Control Study of Clinical Characteristics and Prognosis.Clin Breast Cancer. 2018 Oct;18(5):e875-e882. doi: 10.1016/j.clbc.2018.01.011. Epub 2018 Feb 2.
637 Progenitors from the central nervous system drive neurogenesis in cancer.Nature. 2019 May;569(7758):672-678. doi: 10.1038/s41586-019-1219-y. Epub 2019 May 15.
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641 Eukaryotic Translation Initiation Factor 3a (eIF3a) Promotes Cell Proliferation and Motility in Pancreatic Cancer.J Korean Med Sci. 2016 Oct;31(10):1586-94. doi: 10.3346/jkms.2016.31.10.1586.
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643 Mitogen Inducible Gene-6 Is a Prognostic Marker for Patients with Colorectal Liver Metastases.Transl Oncol. 2019 Mar;12(3):550-560. doi: 10.1016/j.tranon.2018.12.007. Epub 2019 Jan 9.
644 EYA1 promotes cell migration and tumor metastasis in hepatocellular carcinoma.Am J Transl Res. 2019 Apr 15;11(4):2328-2338. eCollection 2019.
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646 Disturbed alternative splicing of FIR (PUF60) directed cyclin E overexpression in esophageal cancers.Oncotarget. 2018 May 1;9(33):22929-22944. doi: 10.18632/oncotarget.25149. eCollection 2018 May 1.
647 Comparison of Claudin 18.2 expression in primary tumors and lymph node metastases in Japanese patients with gastric adenocarcinoma.Jpn J Clin Oncol. 2019 Sep 1;49(9):870-876. doi: 10.1093/jjco/hyz068.
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655 Follistatin-like 1 in development and human diseases.Cell Mol Life Sci. 2018 Jul;75(13):2339-2354. doi: 10.1007/s00018-018-2805-0. Epub 2018 Mar 29.
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658 Uterine leiomyosarcoma and endometrial stromal sarcoma have unique miRNA signatures.Gynecol Oncol. 2016 Mar;140(3):512-7. doi: 10.1016/j.ygyno.2016.01.001. Epub 2016 Jan 6.
659 FAM198B Is Associated with Prolonged Survival and Inhibits Metastasis in Lung Adenocarcinoma via Blockage of ERK-Mediated MMP-1 Expression.Clin Cancer Res. 2018 Feb 15;24(4):916-926. doi: 10.1158/1078-0432.CCR-17-1347. Epub 2017 Dec 7.
660 Overexpression of geranylgeranyl diphosphate synthase contributes to tumour metastasis and correlates with poor prognosis of lung adenocarcinoma.J Cell Mol Med. 2018 Apr;22(4):2177-2189. doi: 10.1111/jcmm.13493. Epub 2018 Jan 29.
661 GPAA1 promotes gastric cancer progression via upregulation of GPI-anchored protein and enhancement of ERBB signalling pathway.J Exp Clin Cancer Res. 2019 May 22;38(1):214. doi: 10.1186/s13046-019-1218-8.
662 GPRC5A is a potential oncogene in pancreatic ductal adenocarcinoma cells that is upregulated by gemcitabine with help from HuR.Cell Death Dis. 2016 Jul 14;7(7):e2294. doi: 10.1038/cddis.2016.169.
663 H2A.Z regulates tumorigenesis, metastasis and sensitivity to cisplatin in intrahepatic cholangiocarcinoma.Int J Oncol. 2018 Apr;52(4):1235-1245. doi: 10.3892/ijo.2018.4292. Epub 2018 Feb 28.
664 Extraneural Metastases From a High-Grade Glioma (HGG) With an H3F3A G34R Mutation.Front Oncol. 2019 May 8;9:373. doi: 10.3389/fonc.2019.00373. eCollection 2019.
665 The E3Ubiquitin Ligase HectD1 Suppresses EMT and Metastasis by Targeting the+TIP ACF7 for Degradation.Cell Rep. 2018 Jan 23;22(4):1016-1030. doi: 10.1016/j.celrep.2017.12.096. Epub 2018 Jan 28.
666 Hedgehog Interacting Protein 1 is a Prognostic Marker and Suppresses Cell Metastasis in Gastric Cancer.J Cancer. 2018 Nov 24;9(24):4642-4649. doi: 10.7150/jca.27686. eCollection 2018.
667 Immune Checkpoint Human Endogenous Retrovirus-H Long Terminal Repeat-Associating Protein 2 is Upregulated and Independently Predicts Unfavorable Prognosis in Bladder Urothelial Carcinoma.Nephron. 2019;141(4):256-264. doi: 10.1159/000495887. Epub 2019 Jan 2.
668 miR-200c/141 Regulates Breast Cancer Stem Cell Heterogeneity via Targeting HIPK1/-Catenin Axis.Theranostics. 2018 Nov 10;8(21):5801-5813. doi: 10.7150/thno.29380. eCollection 2018.
669 The expression level and prognostic value of HIPK3 among non-small-cell lung cancer patients in China.Onco Targets Ther. 2018 Oct 25;11:7459-7469. doi: 10.2147/OTT.S166878. eCollection 2018.
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672 HOXB8 promotes tumor metastasis and the epithelial-mesenchymal transition via ZEB2 targets in gastric cancer.J Cancer Res Clin Oncol. 2017 Mar;143(3):385-397. doi: 10.1007/s00432-016-2283-4. Epub 2016 Oct 19.
673 Association Between Interleukin-10 Receptors and the CD45-Immunophenotype of Central Nervous System Tumors: A Preliminary Study.Anticancer Res. 2017 Oct;37(10):5777-5783. doi: 10.21873/anticanres.12019.
674 Screening for Prostate Cancer Starting at Age 50-54 Years. A Population-based Cohort Study.Eur Urol. 2017 Jan;71(1):46-52. doi: 10.1016/j.eururo.2016.03.026. Epub 2016 Apr 13.
675 IRF7 regulates the development of granulocytic myeloid-derived suppressor cells through S100A9 transrepression in cancer.Oncogene. 2017 May 25;36(21):2969-2980. doi: 10.1038/onc.2016.448. Epub 2017 Jan 16.
676 Screening pathogenic genes in oral squamous cell carcinoma based on the mRNA expression microarray data.Int J Mol Med. 2018 Jun;41(6):3597-3603. doi: 10.3892/ijmm.2018.3514. Epub 2018 Feb 27.
677 Knockdown of L1CAM significantly reduces metastasis in a xenograft model of human melanoma: L1CAM is a potential target for anti-melanoma therapy.PLoS One. 2018 Feb 12;13(2):e0192525. doi: 10.1371/journal.pone.0192525. eCollection 2018.
678 KDM4B promotes gastric cancer metastasis by regulating miR-125b-mediated activation of Wnt signaling.J Cell Biochem. 2019 May;120(5):7897-7906. doi: 10.1002/jcb.28065. Epub 2018 Nov 28.
679 Kinesin Family Member 18A (KIF18A) Contributes to the Proliferation, Migration, and Invasion of Lung Adenocarcinoma Cells In Vitro and In Vivo.Dis Markers. 2019 Oct 22;2019:6383685. doi: 10.1155/2019/6383685. eCollection 2019.
680 KLF10 loss in the pancreas provokes activation of SDF-1 and induces distant metastases of pancreatic ductal adenocarcinoma in the Kras(G12D) p53(flox/flox) model.Oncogene. 2017 Sep 28;36(39):5532-5543. doi: 10.1038/onc.2017.155. Epub 2017 Jun 5.
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682 Krppel-like factor 8 induces epithelial-to-mesenchymal transition and promotes invasion of pancreatic cancer cells through transcriptional activation of four and a half LIM-only protein 2.Oncol Lett. 2017 Oct;14(4):4883-4889. doi: 10.3892/ol.2017.6734. Epub 2017 Aug 9.
683 MicroRNA-200b is downregulated and suppresses metastasis by targeting LAMA4 in renal cell carcinoma.EBioMedicine. 2019 Jun;44:439-451. doi: 10.1016/j.ebiom.2019.05.041. Epub 2019 May 23.
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686 ATP7A delivers copper to the lysyl oxidase family of enzymes and promotes tumorigenesis and metastasis.Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):6836-6841. doi: 10.1073/pnas.1817473116. Epub 2019 Mar 19.
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689 Analysis of HSP27 and the Autophagy Marker LC3B(+) Puncta Following Preoperative Chemotherapy Identifies High-Risk Osteosarcoma Patients.Mol Cancer Ther. 2018 Jun;17(6):1315-1323. doi: 10.1158/1535-7163.MCT-17-0901. Epub 2018 Mar 28.
690 Responses to Topical Diphenylcyclopropenone as an Adjunct Treatment for In-Transit Melanoma: A Tertiary Referral Center Experience.Dermatol Surg. 2018 Dec;44(12):1501-1508. doi: 10.1097/DSS.0000000000001603.
691 Combined Effect of Metastasis-Related MicroRNA, miR-34 and miR-124 Family, Methylation on Prognosis of Non-Small-Cell Lung Cancer.Clin Lung Cancer. 2017 Jan;18(1):e13-e20. doi: 10.1016/j.cllc.2016.06.005. Epub 2016 Jun 23.
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693 Mediator Complex Subunit MED1 Protein Expression Is Decreased during Bladder Cancer Progression.Front Med (Lausanne). 2017 Mar 17;4:30. doi: 10.3389/fmed.2017.00030. eCollection 2017.
694 Mitochondrial fission factor is a novel Myc-dependent regulator of mitochondrial permeability in cancer.EBioMedicine. 2019 Oct;48:353-363. doi: 10.1016/j.ebiom.2019.09.017. Epub 2019 Sep 18.
695 Metastatic Brain Tumors Disrupt the Blood-Brain Barrier and Alter Lipid Metabolism by Inhibiting Expression of the Endothelial Cell Fatty Acid Transporter Mfsd2a.Sci Rep. 2018 May 29;8(1):8267. doi: 10.1038/s41598-018-26636-6.
696 Reduced N-acetylglucosaminyltransferase III expression via Smad3 and Erk signaling in TGF-1-induced HCC EMT model.Discov Med. 2017 Jan;23(124):7-17.
697 MLLT10 promotes tumor migration, invasion, and metastasis in human colorectal cancer.Scand J Gastroenterol. 2018 Aug;53(8):964-971. doi: 10.1080/00365521.2018.1481521. Epub 2018 Aug 13.
698 Role of carbohydrate response element-binding protein (ChREBP) in generating an aerobic metabolic phenotype and in breast cancer progression.Br J Cancer. 2014 Feb 4;110(3):715-23. doi: 10.1038/bjc.2013.765. Epub 2013 Dec 24.
699 Identification of key candidate genes involved in melanoma metastasis.Mol Med Rep. 2019 Aug;20(2):903-914. doi: 10.3892/mmr.2019.10314. Epub 2019 May 30.
700 Novel Triazole-Piperazine Hybrid Molecules Induce Apoptosis via Activation of the Mitochondrial Pathway and Exhibit Antitumor Efficacy in Osteosarcoma Xenograft Nude Mice Model.ACS Chem Biol. 2017 Mar 17;12(3):753-768. doi: 10.1021/acschembio.6b01007. Epub 2017 Jan 26.
701 Reduced-Intensity Delayed Intensification in Standard-Risk Pediatric Acute Lymphoblastic Leukemia Defined by Undetectable Minimal Residual Disease: Results of an International Randomized Trial (AIEOP-BFM ALL 2000).J Clin Oncol. 2018 Jan 20;36(3):244-253. doi: 10.1200/JCO.2017.74.4946. Epub 2017 Nov 17.
702 Reciprocal loop of hypoxia-inducible factor-1 (HIF-1) and metastasis-associated protein 2 (MTA2) contributes to the progression of pancreatic carcinoma by suppressing E-cadherin transcription.J Pathol. 2018 Jul;245(3):349-360. doi: 10.1002/path.5089. Epub 2018 Jun 1.
703 MTMR2 promotes invasion and metastasis of gastric cancer via inactivating IFN/STAT1 signaling.J Exp Clin Cancer Res. 2019 May 21;38(1):206. doi: 10.1186/s13046-019-1186-z.
704 MUC13 promotes intrahepatic cholangiocarcinoma progression viaEGFR/PI3K/AKT pathways.J Hepatol. 2020 Apr;72(4):761-773. doi: 10.1016/j.jhep.2019.11.021. Epub 2019 Dec 16.
705 Tumor Progression Is Mediated by Thymosin-4 through a TGF/MRTF Signaling Axis.Mol Cancer Res. 2018 May;16(5):880-893. doi: 10.1158/1541-7786.MCR-17-0715. Epub 2018 Jan 12.
706 The expanding morphological and genetic spectrum of MYOD1-mutant spindle cell/sclerosing rhabdomyosarcomas: a clinicopathological and molecular comparison of mutated and non-mutated cases.Histopathology. 2019 May;74(6):933-943. doi: 10.1111/his.13819. Epub 2019 Apr 4.
707 Racial/ethnic disparities in de novo metastases sites and survival outcomes for patients with primary breast, colorectal, and prostate cancer.Cancer Med. 2018 Apr;7(4):1183-1193. doi: 10.1002/cam4.1322. Epub 2018 Feb 26.
708 B7-H6 expression in human hepatocellular carcinoma and its clinical significance [corrected].Cancer Cell Int. 2018 Sep 4;18:126. doi: 10.1186/s12935-018-0627-7. eCollection 2018.
709 Neuronal calcium sensor 1 (NCS1) promotes motility and metastatic spread of breast cancer cells in vitro and in vivo.FASEB J. 2019 Apr;33(4):4802-4813. doi: 10.1096/fj.201802004R. Epub 2018 Dec 28.
710 Intertumoral Heterogeneity in SCLC Is Influenced by the Cell Type of Origin.Cancer Discov. 2018 Oct;8(10):1316-1331. doi: 10.1158/2159-8290.CD-17-0987. Epub 2018 Sep 18.
711 The YAP1-NMU Axis Is Associated with Pancreatic Cancer Progression and Poor Outcome: Identification of a Novel Diagnostic Biomarker and Therapeutic Target.Cancers (Basel). 2019 Sep 30;11(10):1477. doi: 10.3390/cancers11101477.
712 NPNT promotes early-stage bone metastases in breast cancer by regulation of the osteogenic niche.J Bone Oncol. 2018 Sep 27;13:91-96. doi: 10.1016/j.jbo.2018.09.006. eCollection 2018 Nov.
713 The transcript expression and protein distribution pattern in human colorectal carcinoma reveal a pivotal role of COM-1/p8 as a tumour suppressor.Cancer Genomics Proteomics. 2010 Mar-Apr;7(2):75-80.
714 A double helical motif in OCIAD2 is essential for its localization, interactions and STAT3 activation.Sci Rep. 2018 May 9;8(1):7362. doi: 10.1038/s41598-018-25667-3.
715 Association between the overexpression of PBOV1 and the prognosis of patients with hepatocellular carcinoma.Oncol Lett. 2018 Sep;16(3):3401-3407. doi: 10.3892/ol.2018.9013. Epub 2018 Jun 25.
716 Hematopoietic PBX-interacting protein is a substrate and an inhibitor of the APC/C-Cdc20 complex and regulates mitosis by stabilizing cyclin B1.J Biol Chem. 2019 Jun 28;294(26):10236-10252. doi: 10.1074/jbc.RA118.006733. Epub 2019 May 17.
717 The role of histopathologic testing on apocrine carcinoma of the breast.Curr Probl Cancer. 2020 Apr;44(2):100501. doi: 10.1016/j.currproblcancer.2019.100501. Epub 2019 Sep 7.
718 Expression of PIWIL3 in primary and metastatic melanoma.J Cancer Res Clin Oncol. 2017 Mar;143(3):433-437. doi: 10.1007/s00432-016-2305-2. Epub 2016 Nov 17.
719 Analysis of oncogenic activities of protein kinase D1 in head and neck squamous cell carcinoma.BMC Cancer. 2018 Nov 12;18(1):1107. doi: 10.1186/s12885-018-4965-6.
720 PLOD3 promotes lung metastasis via regulation of STAT3.Cell Death Dis. 2018 Nov 15;9(12):1138. doi: 10.1038/s41419-018-1186-5.
721 Divergent roles of Plexin D1 in cancer.Biochim Biophys Acta Rev Cancer. 2019 Aug;1872(1):103-110. doi: 10.1016/j.bbcan.2019.05.004. Epub 2019 May 30.
722 POH1 contributes to hyperactivation of TGF- signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF- receptors and caveolin-1.EBioMedicine. 2019 Mar;41:320-332. doi: 10.1016/j.ebiom.2019.01.058. Epub 2019 Feb 7.
723 Outcomes of surgery for gastric cancer with distant metastases: a retrospective study from the SEER database.Oncotarget. 2017 Jan 17;8(3):4342-4351. doi: 10.18632/oncotarget.14027.
724 Prostate Tumor Overexpressed-1 (PTOV1) promotes docetaxel-resistance and survival of castration resistant prostate cancer cells.Oncotarget. 2017 Jul 22;8(35):59165-59180. doi: 10.18632/oncotarget.19467. eCollection 2017 Aug 29.
725 PTPRM, a candidate tumor suppressor gene in small intestinal neuroendocrine tumors.Endocr Connect. 2019 Aug 1;8(8):1126-1135. doi: 10.1530/EC-19-0279.
726 RAB27A, RAB27B and VPS36 are downregulated in advanced prostate cancer and show functional relevance in prostate cancer cells.Int J Oncol. 2017 Mar;50(3):920-932. doi: 10.3892/ijo.2017.3872. Epub 2017 Feb 10.
727 Low expression of Rap1GAP is associated with epithelial-mesenchymal transition (EMT) and poor prognosis in gastric cancer.Oncotarget. 2017 Jan 31;8(5):8057-8068. doi: 10.18632/oncotarget.14074.
728 A somatic mutation of RasGRP3 decreases Na(+)/I(-) symporter expression in metastases of radioactive iodine-refractory thyroid cancer by stimulating the Akt signaling pathway.Am J Cancer Res. 2018 Sep 1;8(9):1847-1855. eCollection 2018.
729 RHBDD1 promotes colorectal cancer metastasis through the Wnt signaling pathway and its downstream target ZEB1.J Exp Clin Cancer Res. 2018 Feb 9;37(1):22. doi: 10.1186/s13046-018-0687-5.
730 Synergistic inhibition of aggressive breast cancer cell migration and invasion by cytoplasmic delivery of anti-RhoC silencing RNA and presentation of EPPT1 peptide on "smart" particles.J Control Release. 2018 Nov 10;289:79-93. doi: 10.1016/j.jconrel.2018.07.042. Epub 2018 Aug 24.
731 RPLP1 promotes tumor metastasis and is associated with a poor prognosis in triple-negative breast cancer patients.Cancer Cell Int. 2018 Oct 25;18:170. doi: 10.1186/s12935-018-0658-0. eCollection 2018.
732 Sec23a mediates miR-200c augmented oligometastatic to polymetastatic progression.EBioMedicine. 2018 Nov;37:47-55. doi: 10.1016/j.ebiom.2018.10.002. Epub 2018 Oct 6.
733 Axon Guidance Molecules Promote Perineural Invasion and Metastasis of Orthotopic Pancreatic Tumors in Mice.Gastroenterology. 2019 Sep;157(3):838-850.e6. doi: 10.1053/j.gastro.2019.05.065. Epub 2019 Jun 1.
734 Neuroimmune Semaphorin 4A in Cancer Angiogenesis and Inflammation: A Promoter or a Suppressor?.Int J Mol Sci. 2018 Dec 30;20(1):124. doi: 10.3390/ijms20010124.
735 Advances in nanomedicine for cancer starvation therapy.Theranostics. 2019 Oct 17;9(26):8026-8047. doi: 10.7150/thno.38261. eCollection 2019.
736 SHROOM2 inhibits tumor metastasis through RhoA-ROCK pathway-dependent and -independent mechanisms in nasopharyngeal carcinoma.Cell Death Dis. 2019 Jan 25;10(2):58. doi: 10.1038/s41419-019-1325-7.
737 Development and validation of SIRT3-related nomogram predictive of overall survival in patients with serous ovarian cancer.J Ovarian Res. 2019 May 21;12(1):47. doi: 10.1186/s13048-019-0524-2.
738 SND1 acts as a novel gene transcription activator recognizing the conserved Motif domains of Smad promoters, inducing TGF1 response and breast cancer metastasis.Oncogene. 2017 Jul 6;36(27):3903-3914. doi: 10.1038/onc.2017.30. Epub 2017 Mar 6.
739 Syntaphilin Is a Novel Biphasic Biomarker of Aggressive Prostate Cancer and a Metastasis Predictor.Am J Pathol. 2019 Jun;189(6):1180-1189. doi: 10.1016/j.ajpath.2019.02.009. Epub 2019 May 9.
740 SORBS1 suppresses tumor metastasis and improves the sensitivity of cancer to chemotherapy drug.Oncotarget. 2017 Feb 7;8(6):9108-9122. doi: 10.18632/oncotarget.12851.
741 SOX17 Inhibits Tumor Metastasis Via Wnt Signaling In Endometrial Cancer.Onco Targets Ther. 2019 Oct 7;12:8275-8286. doi: 10.2147/OTT.S220536. eCollection 2019.
742 R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syndrome and hemangioma.Elife. 2019 Jul 30;8:e43026. doi: 10.7554/eLife.43026.
743 Effect of apalutamide on health-related quality of life in patients with non-metastatic castration-resistant prostate cancer: an analysis of the SPARTAN randomised, placebo-controlled, phase 3 trial.Lancet Oncol. 2018 Oct;19(10):1404-1416. doi: 10.1016/S1470-2045(18)30456-X. Epub 2018 Sep 10.
744 Pan-cancer Convergence to a Small-Cell Neuroendocrine Phenotype that Shares Susceptibilities with Hematological Malignancies.Cancer Cell. 2019 Jul 8;36(1):17-34.e7. doi: 10.1016/j.ccell.2019.06.005.
745 Stress-inducible Protein-1 promotes metastasis of gastric cancer via Wnt/-catenin signaling pathway.J Exp Clin Cancer Res. 2018 Jan 15;37(1):6. doi: 10.1186/s13046-018-0676-8.
746 Hippo kinases regulate cell junctions to inhibit tumor metastasis in response to oxidative stress.Redox Biol. 2019 Sep;26:101233. doi: 10.1016/j.redox.2019.101233. Epub 2019 Jun 4.
747 Neurotensin/IL-8 pathway orchestrates local inflammatory response and tumor invasion by inducing M2 polarization of Tumor-Associated macrophages and epithelial-mesenchymal transition of hepatocellular carcinoma cells.Oncoimmunology. 2018 Mar 13;7(7):e1440166. doi: 10.1080/2162402X.2018.1440166. eCollection 2018.
748 Loss of the transcriptional repressor TGIF1 results in enhanced Kras-driven development of pancreatic cancer.Mol Cancer. 2019 May 20;18(1):96. doi: 10.1186/s12943-019-1023-1.
749 Expression of transmembrane protein 41A is associated with metastasis via the modulation of Ecadherin in radically resected gastric cancer.Mol Med Rep. 2018 Sep;18(3):2963-2972. doi: 10.3892/mmr.2018.9241. Epub 2018 Jul 3.
750 Thymosin beta 10 is a key regulator of tumorigenesis and metastasis and a novel serum marker in breast cancer.Breast Cancer Res. 2017 Feb 8;19(1):15. doi: 10.1186/s13058-016-0785-2.
751 Knockdown of TNFAIP1 inhibits growth and induces apoptosis in osteosarcoma cells through inhibition of the nuclear factor-B pathway.Oncol Rep. 2014 Sep;32(3):1149-55. doi: 10.3892/or.2014.3291. Epub 2014 Jun 25.
752 Expression of Tumor-mediated CD137 ligand in human colon cancer indicates dual signaling effects.Oncoimmunology. 2019 Sep 6;8(12):e1651622. doi: 10.1080/2162402X.2019.1651622. eCollection 2019.
753 Expression of LUN gene that encodes a novel RING finger protein is correlated with development and progression of non-small cell lung cancer.Lung Cancer. 2004 Oct;46(1):21-8. doi: 10.1016/j.lungcan.2004.03.009.
754 High expression of tumor necrosis factor receptor-associated factor 2 promotes tumor metastasis and is associated with unfavorable prognosis in gastric cancer.J Gastroenterol Hepatol. 2018 Feb;33(2):431-442. doi: 10.1111/jgh.13818.
755 Tripartite motif 31 promotes resistance to anoikis of hepatocarcinoma cells through regulation of p53-AMPK axis.Exp Cell Res. 2018 Jul 1;368(1):59-66. doi: 10.1016/j.yexcr.2018.04.013. Epub 2018 Apr 14.
756 TRIM44 activates the AKT/mTOR signal pathway to induce melanoma progression by stabilizing TLR4.J Exp Clin Cancer Res. 2019 Mar 28;38(1):137. doi: 10.1186/s13046-019-1138-7.
757 Serum Levels of TRIM72 Are Lower among Patients with Colon Cancer: Identification of a Potential Diagnostic Marker.Tohoku J Exp Med. 2018 May;245(1):61-68. doi: 10.1620/tjem.245.61.
758 TTC4, a novel candidate tumor suppressor gene at 1p31 is often mutated in malignant melanoma of the skin.Oncogene. 2000 Nov 23;19(50):5817-20. doi: 10.1038/sj.onc.1203961.
759 Prospective Immunophenotyping of CD8(+) T Cells and Associated Clinical Outcomes of Patients With Oligometastatic Prostate Cancer Treated With Metastasis-Directed SBRT.Int J Radiat Oncol Biol Phys. 2019 Jan 1;103(1):229-240. doi: 10.1016/j.ijrobp.2018.09.001. Epub 2018 Sep 8.
760 Considering tumour volume for motion corrected DWI of colorectal liver metastases increases sensitivity of ADC to detect treatment-induced changes.Sci Rep. 2019 Mar 7;9(1):3828. doi: 10.1038/s41598-019-40565-y.
761 Factors Predicting Response, Perioperative Outcomes, and Survival Following Total Neoadjuvant Therapy for Borderline/Locally Advanced Pancreatic Cancer.Ann Surg. 2021 Feb 1;273(2):341-349. doi: 10.1097/SLA.0000000000003284.
762 Arsenic Trioxide Inhibits the Metastasis of Small Cell Lung Cancer by Blocking Calcineurin-Nuclear Factor of Activated T Cells (NFAT) Signaling.Med Sci Monit. 2019 Mar 26;25:2228-2237. doi: 10.12659/MSM.913091.
763 CADM2, as a new target of miR-10b, promotes tumor metastasis through FAK/AKT pathway in hepatocellular carcinoma.J Exp Clin Cancer Res. 2018 Mar 5;37(1):46. doi: 10.1186/s13046-018-0699-1.
764 Evaluation of Gadopiclenol and P846, 2 High-Relaxivity Macrocyclic Magnetic Resonance Contrast Agents Without Protein Binding, in a Rodent Model of Hepatic Metastases: Potential Solutions for Improved Enhancement at Ultrahigh Field Strength.Invest Radiol. 2019 Sep;54(9):549-558. doi: 10.1097/RLI.0000000000000572.
765 Interaction of CD200 Overexpression on Tumor Cells with CD200R1 Overexpression on Stromal Cells: An Escape from the Host Immune Response in Rectal Cancer Patients.J Oncol. 2019 Jan 21;2019:5689464. doi: 10.1155/2019/5689464. eCollection 2019.
766 A Clinically Applicable Gene-Expression Classifier Reveals Intrinsic and Extrinsic Contributions to Consensus Molecular Subtypes in Primary and Metastatic Colon Cancer.Clin Cancer Res. 2019 Jul 15;25(14):4431-4442. doi: 10.1158/1078-0432.CCR-18-3032. Epub 2019 Apr 19.
767 Pathway crosstalk analysis in prostate cancer based on protein-protein network data.Neoplasma. 2017;64(1):22-31. doi: 10.4149/neo_2017_103.
768 Restin suppressed epithelial-mesenchymal transition and tumor metastasis in breast cancer cells through upregulating mir-200a/b expression via association with p73.Mol Cancer. 2015 May 14;14:102. doi: 10.1186/s12943-015-0370-9.
769 Overexpression of CMTM7 inhibits cell growth and migration in liver cancer.Kaohsiung J Med Sci. 2019 Jun;35(6):332-340. doi: 10.1002/kjm2.12058. Epub 2019 Mar 23.
770 Cancer-associated stroma significantly contributes to the mesenchymal subtype signature of serous ovarian cancer.Gynecol Oncol. 2019 Feb;152(2):368-374. doi: 10.1016/j.ygyno.2018.11.014. Epub 2018 Nov 15.
771 Long Noncoding RNA GMAN, Up-regulated in Gastric Cancer Tissues, Is Associated With Metastasis in Patients and Promotes Translation of Ephrin A1 by Competitively Binding GMAN-AS.Gastroenterology. 2019 Feb;156(3):676-691.e11. doi: 10.1053/j.gastro.2018.10.054. Epub 2018 Nov 13.
772 Up-regulated LINC00261 predicts a poor prognosis and promotes a metastasis by EMT process in cholangiocarcinoma.Pathol Res Pract. 2020 Jan;216(1):152733. doi: 10.1016/j.prp.2019.152733. Epub 2019 Nov 11.
773 GAGE7B promotes tumor metastasis and growth via activating the p38/pMAPKAPK2/pHSP27 pathway in gastric cancer.J Exp Clin Cancer Res. 2019 Mar 11;38(1):124. doi: 10.1186/s13046-019-1125-z.
774 IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties.Nucleic Acids Res. 2019 May 7;47(8):4334-4348. doi: 10.1093/nar/gkz136.
775 Gene expression profile analysis of ENO1 knockdown in gastric cancer cell line MGC-803.Oncol Lett. 2019 Apr;17(4):3881-3889. doi: 10.3892/ol.2019.10053. Epub 2019 Feb 19.
776 PYHIN genes as potential biomarkers for prognosis of human papillomavirus-positive or -negative head and neck squamous cell carcinomas.Mol Biol Rep. 2019 Jun;46(3):3333-3347. doi: 10.1007/s11033-019-04795-7. Epub 2019 Apr 12.
777 Downregulation of IQGAP2 Correlates with Prostate Cancer Recurrence and Metastasis.Transl Oncol. 2019 Feb;12(2):236-244. doi: 10.1016/j.tranon.2018.10.009. Epub 2018 Nov 11.
778 Loss of MADD expression inhibits cellular growth and metastasis in anaplastic thyroid cancer.Cell Death Dis. 2019 Feb 13;10(2):145. doi: 10.1038/s41419-019-1351-5.
779 Time-dependent transcriptional profiling links gene expression to mitogen-activated protein kinase kinase 4 (MKK4)-mediated suppression of omental metastatic colonization.Clin Exp Metastasis. 2012 Jun;29(5):397-408. doi: 10.1007/s10585-011-9448-y. Epub 2012 Feb 21.
780 MEST induces Twist-1-mediated EMT through STAT3 activation in breast cancers.Cell Death Differ. 2019 Dec;26(12):2594-2606. doi: 10.1038/s41418-019-0322-9. Epub 2019 Mar 22.
781 Specific-detection of clinical samples, systematic functional investigations, and transcriptome analysis reveals that splice variant MUC4/Y contributes to the malignant progression of pancreatic cancer by triggering malignancy-related positive feedback loops signaling.J Transl Med. 2014 Nov 4;12:309. doi: 10.1186/s12967-014-0309-8.
782 Expression of cellular adhesion molecule 'OPCML' is down-regulated in gliomas and other brain tumours.Neuropathol Appl Neurobiol. 2007 Feb;33(1):77-85. doi: 10.1111/j.1365-2990.2006.00786.x.
783 Expression of OPN3 in lung adenocarcinoma promotes epithelial-mesenchymal transition and tumor metastasis.Thorac Cancer. 2020 Feb;11(2):286-294. doi: 10.1111/1759-7714.13254. Epub 2019 Dec 5.
784 PARP10 suppresses tumor metastasis through regulation of Aurora A activity.Oncogene. 2018 May;37(22):2921-2935. doi: 10.1038/s41388-018-0168-5. Epub 2018 Mar 8.
785 PDCD5 inhibits osteosarcoma cell metastasis via targeting TGF-1/Smad signaling pathway and is associated with good prognosis.Am J Transl Res. 2019 Feb 15;11(2):1116-1128. eCollection 2019.
786 High frequency of POLE mutations in synchronous endometrial and ovarian carcinoma.Hum Pathol. 2019 Mar;85:92-100. doi: 10.1016/j.humpath.2018.11.001. Epub 2018 Nov 15.
787 High-level expression of PRSS3 correlates with metastasis and poor prognosis in patients with gastric cancer.J Surg Oncol. 2019 Jun;119(8):1108-1121. doi: 10.1002/jso.25448. Epub 2019 Mar 25.
788 Autoantibody against arrestin-1 as a potential biomarker of renal cell carcinoma.Biochimie. 2019 Feb;157:26-37. doi: 10.1016/j.biochi.2018.10.019. Epub 2018 Oct 30.
789 Interferon-regulated suprabasin is essential for stress-induced stem-like cell conversion and therapy resistance of human malignancies.Mol Oncol. 2019 Jul;13(7):1467-1489. doi: 10.1002/1878-0261.12480. Epub 2019 Jun 10.
790 Promoter hypermethylation and silencing of tissue factor pathway inhibitor-2 in oral squamous cell carcinoma.J Transl Med. 2014 Sep 2;12:237. doi: 10.1186/s12967-014-0237-7.
791 Long noncoding RNA CAR10 promotes lung adenocarcinoma metastasis via miR-203/30/SNAI axis.Oncogene. 2019 Apr;38(16):3061-3076. doi: 10.1038/s41388-018-0645-x. Epub 2019 Jan 7.
792 The Adhesion G-Protein-Coupled Receptor, GPR56/ADGRG1, Inhibits Cell-Extracellular Matrix Signaling to Prevent Metastatic Melanoma Growth.Front Oncol. 2018 Feb 1;8:8. doi: 10.3389/fonc.2018.00008. eCollection 2018.
793 Isoprenylcysteine carboxylmethyltransferase function is essential for RAB4A-mediated integrin 3 recycling, cell migration and cancer metastasis.Oncogene. 2017 Oct 12;36(41):5757-5767. doi: 10.1038/onc.2017.183. Epub 2017 Jun 12.
794 Depletion of ALX1 causes inhibition of migration and induction of apoptosis in human osteosarcoma.Tumour Biol. 2015 Aug;36(8):5965-70. doi: 10.1007/s13277-015-3271-z. Epub 2015 Mar 4.
795 Overexpression of annexin A4 indicates poor prognosis and promotes tumor metastasis of hepatocellular carcinoma.Tumour Biol. 2016 Jul;37(7):9343-55. doi: 10.1007/s13277-016-4823-6. Epub 2016 Jan 16.
796 AQP5 promotes hepatocellular carcinoma metastasis via NF-B-regulated epithelial-mesenchymal transition.Biochem Biophys Res Commun. 2017 Aug 19;490(2):343-348. doi: 10.1016/j.bbrc.2017.06.046. Epub 2017 Jun 12.
797 High expression of ASPM correlates with tumor progression and predicts poor outcome in patients with prostate cancer.Int Urol Nephrol. 2017 May;49(5):817-823. doi: 10.1007/s11255-017-1545-7. Epub 2017 Feb 17.
798 A Novel Pak1/ATF2/miR-132 Signaling Axis Is Involved in the Hematogenous Metastasis of Gastric Cancer Cells.Mol Ther Nucleic Acids. 2017 Sep 15;8:370-382. doi: 10.1016/j.omtn.2017.07.005. Epub 2017 Jul 8.
799 ATG4A promotes tumor metastasis by inducing the epithelial-mesenchymal transition and stem-like properties in gastric cells.Oncotarget. 2016 Jun 28;7(26):39279-39292. doi: 10.18632/oncotarget.9827.
800 Activation of the basal cell carcinoma pathway in a patient with CNS HGNET-BCOR diagnosis: consequences for personalized targeted therapy.Oncotarget. 2016 Dec 13;7(50):83378-83391. doi: 10.18632/oncotarget.13092.
801 Primary pulmonary adenoid cystic carcinoma: clinicopathological analyses of 12 cases.Int J Clin Exp Pathol. 2015 Jun 1;8(6):7619-26. eCollection 2015.
802 WBSCR22 confers oxaliplatin resistance in human colorectal cancer.Sci Rep. 2017 Nov 13;7(1):15443. doi: 10.1038/s41598-017-15749-z.
803 Calpain-3 impairs cell proliferation and stimulates oxidative stress-mediated cell death in melanoma cells.PLoS One. 2015 Feb 6;10(2):e0117258. doi: 10.1371/journal.pone.0117258. eCollection 2015.
804 The CBM Complex Underwrites NF-B Activation to Promote HER2-Associated Tumor Malignancy.Mol Cancer Res. 2016 Jan;14(1):93-102. doi: 10.1158/1541-7786.MCR-15-0229-T. Epub 2015 Sep 21.
805 miR-27a and miR-27a* contribute to metastatic properties of osteosarcoma cells.Oncotarget. 2015 Mar 10;6(7):4920-35. doi: 10.18632/oncotarget.3025.
806 CBX8 Suppresses Tumor Metastasis via Repressing Snail in Esophageal Squamous Cell Carcinoma.Theranostics. 2017 Aug 15;7(14):3478-3488. doi: 10.7150/thno.20717. eCollection 2017.
807 STAT3 protein up-regulates G-interacting vesicle-associated protein (GIV)/Girdin expression, and GIV enhances STAT3 activation in a positive feedback loop during wound healing and tumor invasion/metastasis.J Biol Chem. 2012 Dec 7;287(50):41667-83. doi: 10.1074/jbc.M112.390781. Epub 2012 Oct 12.
808 CD81 Promotes a Migratory Phenotype in Neuronal-Like Cells.Microsc Microanal. 2019 Feb;25(1):229-235. doi: 10.1017/S1431927618015532. Epub 2019 Feb 4.
809 A signal-based method for finding driver modules of breast cancer metastasis to the lung.Sci Rep. 2017 Aug 30;7(1):10023. doi: 10.1038/s41598-017-09951-2.
810 KIAA1199 promotes metastasis of colorectal cancer cells via microtubule destabilization regulated by a PP2A/stathmin pathway.Oncogene. 2019 Feb;38(7):935-949. doi: 10.1038/s41388-018-0493-8. Epub 2018 Sep 10.
811 Phosphorylation of cofilin-1 by ERK confers HDAC inhibitor resistance in hepatocellular carcinoma cells via decreased ROS-mediated mitochondria injury.Oncogene. 2017 Apr 6;36(14):1978-1990. doi: 10.1038/onc.2016.357. Epub 2016 Oct 17.
812 Chemokine and Chemokine Receptor Profiles in Metastatic Salivary Adenoid Cystic Carcinoma.Anticancer Res. 2016 Aug;36(8):4013-8.
813 Knockdown of CMTM3 promotes metastasis of gastric cancer via the STAT3/Twist1/EMT signaling pathway.Oncotarget. 2016 May 17;7(20):29507-19. doi: 10.18632/oncotarget.8789.
814 miR-644a Inhibits Cellular Proliferation and Invasion via Suppression of CtBP1 in Gastric Cancer Cells.Oncol Res. 2018 Jan 19;26(1):1-8. doi: 10.3727/096504016X14772410356982. Epub 2017 Nov 29.
815 CTHRC1 promotes M2-like macrophage recruitment and myometrial invasion in endometrial carcinoma by integrin-Akt signaling pathway.Clin Exp Metastasis. 2019 Aug;36(4):351-363. doi: 10.1007/s10585-019-09971-4. Epub 2019 May 22.
816 P120 Catenin Isoforms Differentially Associate with Breast Cancer Invasion and Metastasis.Cancers (Basel). 2019 Sep 29;11(10):1459. doi: 10.3390/cancers11101459.
817 Knockdown of CUL4A inhibits invasion and induces apoptosis in osteosarcoma cells.Int J Immunopathol Pharmacol. 2015 Jun;28(2):263-9. doi: 10.1177/0394632015586656. Epub 2015 Jun 8.
818 CYC1 Predicts Poor Prognosis in Patients with Breast Cancer.Dis Markers. 2016;2016:3528064. doi: 10.1155/2016/3528064. Epub 2016 Apr 28.
819 Targeted genomic sequencing of follicular dendritic cell sarcoma reveals recurrent alterations in NF-B regulatory genes.Mod Pathol. 2016 Jan;29(1):67-74. doi: 10.1038/modpathol.2015.130. Epub 2015 Nov 13.
820 Cell cycle-coupled expansion of AR activity promotes cancer progression.Oncogene. 2017 Mar 23;36(12):1655-1668. doi: 10.1038/onc.2016.334. Epub 2016 Sep 26.
821 Exosomes in Nasopharyngeal Carcinoma.J Cancer. 2018 Feb 11;9(5):767-777. doi: 10.7150/jca.22505. eCollection 2018.
822 DLC-1 tumor suppressor regulates CD105 expression on human non-small cell lung carcinoma cells through inhibiting TGF-1 signaling.Exp Cell Res. 2020 Jan 15;386(2):111732. doi: 10.1016/j.yexcr.2019.111732. Epub 2019 Nov 23.
823 DNM3 Attenuates Hepatocellular Carcinoma Growth by Activating P53.Med Sci Monit. 2016 Jan 19;22:197-205. doi: 10.12659/msm.896545.
824 MiR-122-5p inhibits cell migration and invasion in gastric cancer by down-regulating DUSP4.Cancer Biol Ther. 2018 May 4;19(5):427-435. doi: 10.1080/15384047.2018.1423925. Epub 2018 Mar 6.
825 A prospective study to assess the clinical utility of serum HER2 extracellular domain in breast cancer with HER2 overexpression.Breast Cancer Res Treat. 2016 Nov;160(2):249-259. doi: 10.1007/s10549-016-4000-z. Epub 2016 Oct 5.
826 Extracellular matrix protein 1 promotes cell metastasis and glucose metabolism by inducing integrin 4/FAK/SOX2/HIF-1 signaling pathway in gastric cancer.Oncogene. 2018 Feb 8;37(6):744-755. doi: 10.1038/onc.2017.363. Epub 2017 Oct 23.
827 Counter regulation of ECRG4 gene expression by hypermethylation-dependent inhibition and the Sp1 transcription factor-dependent stimulation of the c2orf40 promoter.Gene. 2017 Dec 15;636:103-111. doi: 10.1016/j.gene.2017.08.041. Epub 2017 Sep 1.
828 Role of Epithelial Cell Transforming Sequence 2 (ECT2) in Predicting Prognosis of Osteosarcoma.Med Sci Monit. 2017 Aug 10;23:3861-3868. doi: 10.12659/msm.905951.
829 Epithelial membrane protein 1 promotes tumor metastasis by enhancing cell migration via copine-III and Rac1.Oncogene. 2018 Oct;37(40):5416-5434. doi: 10.1038/s41388-018-0286-0. Epub 2018 Jun 4.
830 EMP2 is a novel therapeutic target for endometrial cancer stem cells.Oncogene. 2017 Oct 19;36(42):5793-5807. doi: 10.1038/onc.2017.142. Epub 2017 Jun 12.
831 The important role of circulating CYFRA21-1 in metastasis diagnosis and prognostic value compared with carcinoembryonic antigen and neuron-specific enolase in lung cancer patients.BMC Cancer. 2017 Feb 2;17(1):96. doi: 10.1186/s12885-017-3070-6.
832 Epithelial Splicing Regulatory Protein 1 Inhibits the Invasion and Metastasis of Lung Adenocarcinoma.Am J Pathol. 2018 Aug;188(8):1882-1894. doi: 10.1016/j.ajpath.2018.04.012. Epub 2018 May 24.
833 miR-17-5p suppresses cell proliferation and invasion by targeting ETV1 in triple-negative breast cancer.BMC Cancer. 2017 Nov 10;17(1):745. doi: 10.1186/s12885-017-3674-x.
834 Interleukin-like EMT inducer regulates partial phenotype switching in MITF-low melanoma cell lines.PLoS One. 2017 May 17;12(5):e0177830. doi: 10.1371/journal.pone.0177830. eCollection 2017.
835 Genetic polymorphisms and response to 5-fluorouracil, doxorubicin and cyclophosphamide chemotherapy in breast cancer patients.Oncotarget. 2016 Oct 11;7(41):66790-66808. doi: 10.18632/oncotarget.11053.
836 Downregulation of FBP1 Promotes Tumor Metastasis and Indicates Poor Prognosis in Gastric Cancer via Regulating Epithelial-Mesenchymal Transition.PLoS One. 2016 Dec 15;11(12):e0167857. doi: 10.1371/journal.pone.0167857. eCollection 2016.
837 FBXO32 promotes microenvironment underlying epithelial-mesenchymal transition via CtBP1 during tumour metastasis and brain development.Nat Commun. 2017 Nov 15;8(1):1523. doi: 10.1038/s41467-017-01366-x.
838 Regulation of FBXO4-mediated ICAM-1 protein stability in metastatic breast cancer.Oncotarget. 2017 Sep 15;8(47):83100-83113. doi: 10.18632/oncotarget.20912. eCollection 2017 Oct 10.
839 FKBP14 overexpression contributes to osteosarcoma carcinogenesis and indicates poor survival outcome.Oncotarget. 2016 Jun 28;7(26):39872-39884. doi: 10.18632/oncotarget.9524.
840 Limbs and trunk soft tissue sarcoma systematic local and remote monitoring by MRI and thoraco-abdomino-pelvic scanner: Asingle-centre retrospective study.Eur J Surg Oncol. 2019 Jul;45(7):1274-1280. doi: 10.1016/j.ejso.2019.02.002. Epub 2019 Feb 5.
841 MiR-200c inhibits metastasis of breast tumor via the downregulation of Foxf2.Genet Mol Res. 2017 Aug 17;16(3). doi: 10.4238/gmr16038971.
842 Oncogene FOXK1 enhances invasion of colorectal carcinoma by inducing epithelial-mesenchymal transition.Oncotarget. 2016 Aug 9;7(32):51150-51162. doi: 10.18632/oncotarget.9457.
843 Novel role of forkhead box O 4 transcription factor in cancer: Bringing out the good or the bad.Semin Cancer Biol. 2018 Jun;50:1-12. doi: 10.1016/j.semcancer.2018.04.007. Epub 2018 Apr 30.
844 Promotion of epithelial-mesenchymal transition by Frizzled2 is involved in the metastasis of endometrial cancer.Oncol Rep. 2016 Aug;36(2):803-10. doi: 10.3892/or.2016.4885. Epub 2016 Jun 17.
845 FZD2 regulates cell proliferation and invasion in tongue squamous cell carcinoma.Int J Biol Sci. 2019 Aug 24;15(11):2330-2339. doi: 10.7150/ijbs.33881. eCollection 2019.
846 Matrix stiffness drives epithelial-mesenchymal transition and tumour metastasis through a TWIST1-G3BP2 mechanotransduction pathway.Nat Cell Biol. 2015 May;17(5):678-88. doi: 10.1038/ncb3157. Epub 2015 Apr 20.
847 GALNT14 promotes lung-specific breast cancer metastasis by modulating self-renewal and interaction with the lung microenvironment.Nat Commun. 2016 Dec 16;7:13796. doi: 10.1038/ncomms13796.
848 LONG-TERM OUTCOMES AND PROGNOSTIC FACTORS IN PATIENTS WITH DIFFERENTIATED THYROID CARCINOMA AND BONE METASTASES.Endocr Pract. 2019 May;25(5):427-437. doi: 10.4158/EP-2018-0465. Epub 2019 Jan 18.
849 Loss of GFAT1 promotes epithelial-to-mesenchymal transition and predicts unfavorable prognosis in gastric cancer.Oncotarget. 2016 Jun 21;7(25):38427-39. doi: 10.18632/oncotarget.9538.
850 Identification of GOLM1 as a positively regulator of tumor metastasis by regulating MMP13 in gastric carcinoma.Cancer Biomark. 2019;26(4):421-430. doi: 10.3233/CBM-190301.
851 Therapeutically targeting glypican-2 via single-domain antibody-based chimeric antigen receptors and immunotoxins in neuroblastoma.Proc Natl Acad Sci U S A. 2017 Aug 8;114(32):E6623-E6631. doi: 10.1073/pnas.1706055114. Epub 2017 Jul 24.
852 The insulin resistance Grb14 adaptor protein promotes thyroid cancer ret signaling and progression.Oncogene. 2012 Sep 6;31(36):4012-21. doi: 10.1038/onc.2011.569. Epub 2011 Dec 12.
853 Identification of reciprocal microRNA-mRNA pairs associated with metastatic potential disparities in human prostate cancer cells and signaling pathway analysis.J Cell Biochem. 2019 Oct;120(10):17779-17790. doi: 10.1002/jcb.29045. Epub 2019 May 24.
854 miR-133b suppresses metastasis by targeting HOXA9 in human colorectal cancer.Oncotarget. 2017 Jul 12;8(38):63935-63948. doi: 10.18632/oncotarget.19212. eCollection 2017 Sep 8.
855 Overexpression of IFN-induced protein with tetratricopeptide repeats 3 (IFIT3) in pancreatic cancer: cellular "pseudoinflammation" contributing to an aggressive phenotype.Oncotarget. 2015 Feb 20;6(5):3306-18. doi: 10.18632/oncotarget.2494.
856 IFITM3 promotes hepatocellular carcinoma invasion and metastasis by regulating MMP9 through p38/MAPK signaling.FEBS Open Bio. 2018 Jun 28;8(8):1299-1311. doi: 10.1002/2211-5463.12479. eCollection 2018 Aug.
857 TGF-1 secreted by Tregs in lymph nodes promotes breast cancer malignancy via up-regulation of IL-17RB.EMBO Mol Med. 2017 Dec;9(12):1660-1680. doi: 10.15252/emmm.201606914.
858 Is miR-34a a Well-equipped Swordsman to Conquer Temple of Molecular Oncology?.Chem Biol Drug Des. 2016 Mar;87(3):321-34. doi: 10.1111/cbdd.12634. Epub 2016 Jan 13.
859 MicroRNA let-7b suppresses human gastric cancer malignancy by targeting ING1.Cancer Gene Ther. 2015 Apr;22(3):122-9. doi: 10.1038/cgt.2014.75. Epub 2015 Jan 23.
860 The expression of inhibitor of growth 4 is reduced in cervical cancer tissues.Eur Rev Med Pharmacol Sci. 2016 Jul;20(15):3178-85.
861 INPP4B inhibits cell proliferation, invasion and chemoresistance in human hepatocellular carcinoma.Onco Targets Ther. 2019 May 7;12:3491-3507. doi: 10.2147/OTT.S196832. eCollection 2019.
862 Insulinoma-associated protein 1 (INSM1) is a sensitive and highly specific marker of neuroendocrine differentiation in primary lung neoplasms: an immunohistochemical study of 345 cases, including 292 whole-tissue sections.Mod Pathol. 2019 Jan;32(1):100-109. doi: 10.1038/s41379-018-0122-7. Epub 2018 Aug 28.
863 Colorectal cancer exosomes induce lymphatic network remodeling in lymph nodes.Int J Cancer. 2019 Sep 15;145(6):1648-1659. doi: 10.1002/ijc.32196. Epub 2019 Feb 20.
864 Whole-exome sequencing reveals critical genes underlying metastasis in oesophageal squamous cell carcinoma.J Pathol. 2017 Aug;242(4):500-510. doi: 10.1002/path.4925. Epub 2017 Jul 12.
865 MOF Acetylates the Histone Demethylase LSD1 to Suppress Epithelial-to-Mesenchymal Transition.Cell Rep. 2016 Jun 21;15(12):2665-78. doi: 10.1016/j.celrep.2016.05.050. Epub 2016 Jun 9.
866 Novel FUS-KLF17 and EWSR1-KLF17 fusions in myoepithelial tumors.Genes Chromosomes Cancer. 2015 May;54(5):267-75. doi: 10.1002/gcc.22240. Epub 2015 Feb 23.
867 Interleukin-12 from CD103(+) Batf3-Dependent Dendritic Cells Required for NK-Cell Suppression of Metastasis.Cancer Immunol Res. 2017 Dec;5(12):1098-1108. doi: 10.1158/2326-6066.CIR-17-0341. Epub 2017 Oct 25.
868 Polyclonal breast cancer metastases arise from collective dissemination of keratin 14-expressing tumor cell clusters.Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):E854-63. doi: 10.1073/pnas.1508541113. Epub 2016 Feb 1.
869 Differential gene expression identifies KRT7 and MUC1 as potential metastasis-specific targets in sarcoma.Cancer Manag Res. 2019 Sep 9;11:8209-8218. doi: 10.2147/CMAR.S218676. eCollection 2019.
870 Basement membrane protein ladinin-1 and the MIF-CD44-1 integrin signaling axis are implicated in laryngeal cancer metastasis.Biochim Biophys Acta. 2016 Oct;1862(10):1938-54. doi: 10.1016/j.bbadis.2016.07.014. Epub 2016 Jul 25.
871 Overexpression of the YAP1 oncogene in clear cell renal cell carcinoma is associated with poor outcome.Oncol Rep. 2017 Jul;38(1):427-439. doi: 10.3892/or.2017.5642. Epub 2017 May 15.
872 microRNA-219-5p inhibits epithelial-mesenchymal transition and metastasis of colorectal cancer by targeting lymphoid enhancer-binding factor 1.Cancer Sci. 2017 Oct;108(10):1985-1995. doi: 10.1111/cas.13338. Epub 2017 Aug 29.
873 Clinicopathological characteristics and molecular abnormalities of primary grade 2 neuroendocrine tumors of the cervix.Diagn Pathol. 2019 Jun 22;14(1):64. doi: 10.1186/s13000-019-0837-x.
874 METTL14 suppresses the metastatic potential of hepatocellular carcinoma by modulating N(6) -methyladenosine-dependent primary MicroRNA processing.Hepatology. 2017 Feb;65(2):529-543. doi: 10.1002/hep.28885. Epub 2016 Dec 24.
875 MIEN1, a novel interactor of Annexin A2, promotes tumor cell migration by enhancing AnxA2 cell surface expression.Mol Cancer. 2015 Aug 15;14:156. doi: 10.1186/s12943-015-0428-8.
876 PKC phosphorylates MIIP and promotes colorectal cancer metastasis through inhibition of RelA deacetylation.Nat Commun. 2017 Oct 16;8(1):939. doi: 10.1038/s41467-017-01024-2.
877 Expression of minichromosome maintenance genes in renal cell carcinoma.Cancer Manag Res. 2017 Nov 15;9:637-647. doi: 10.2147/CMAR.S146528. eCollection 2017.
878 Silencing of advanced glycosylation and glycosylation and product-specific receptor (RAGE) inhibits the metastasis and growth of non-small cell lung cancer.Am J Transl Res. 2017 Jun 15;9(6):2760-2774. eCollection 2017.
879 Notch1-WISP-1 axis determines the regulatory role of mesenchymal stem cell-derived stromal fibroblasts in melanoma metastasis.Oncotarget. 2016 Nov 29;7(48):79262-79273. doi: 10.18632/oncotarget.13021.
880 Adipocytes promote breast cancer resistance to chemotherapy, a process amplified by obesity: role of the major vault protein(MVP).Breast Cancer Res. 2019 Jan 17;21(1):7. doi: 10.1186/s13058-018-1088-6.
881 Brachmann-Cornelia de Lange syndrome with a papilloma of the choroid plexus: analyses of molecular genetic characteristics of the patient and the tumor. A single-case study.Childs Nerv Syst. 2015 Jan;31(1):141-6. doi: 10.1007/s00381-014-2504-6. Epub 2014 Jul 27.
882 Myoferlin regulates cellular lipid metabolism and promotes metastases in triple-negative breast cancer.Oncogene. 2017 Apr;36(15):2116-2130. doi: 10.1038/onc.2016.369. Epub 2016 Oct 24.
883 NAB2-STAT6 fusion gene analysis in two cases of meningeal solitary fibrous tumor/hemangiopericytoma with late distant metastases.Brain Tumor Pathol. 2015 Oct;32(4):268-74. doi: 10.1007/s10014-015-0220-x. Epub 2015 Apr 18.
884 Nuclear Receptor Corepressor 1 Expression and Output Declines with Prostate Cancer Progression.Clin Cancer Res. 2016 Aug 1;22(15):3937-49. doi: 10.1158/1078-0432.CCR-15-1983. Epub 2016 Mar 11.
885 Metastasis-suppressing NID2, an epigenetically-silenced gene, in the pathogenesis of nasopharyngeal carcinoma and esophageal squamous cell carcinoma.Oncotarget. 2016 Nov 29;7(48):78859-78871. doi: 10.18632/oncotarget.12889.
886 MicroRNA-326 functions as a tumor suppressor in colorectal cancer by targeting the nin one binding protein.Oncol Rep. 2015 May;33(5):2309-18. doi: 10.3892/or.2015.3840. Epub 2015 Mar 6.
887 Nodal occult metastases in intermediate- and high-risk prostate cancer patients detected using serial section, immunohistochemistry, and real-time reverse transcriptase polymerase chain reaction: prospective evaluation with matched-pair analysis.Clin Genitourin Cancer. 2015 Apr;13(2):e55-64. doi: 10.1016/j.clgc.2014.08.004. Epub 2014 Aug 9.
888 Upregulation of the Non-Coding RNA OTUB1-isoform 2 Contributes to Gastric Cancer Cell Proliferation and Invasion and Predicts Poor Gastric Cancer Prognosis.Int J Biol Sci. 2016 Mar 3;12(5):545-57. doi: 10.7150/ijbs.13540. eCollection 2016.
889 An update on the LIM and SH3 domain protein 1 (LASP1): a versatile structural, signaling, and biomarker protein.Oncotarget. 2015 Jan 1;6(1):26-42. doi: 10.18632/oncotarget.3083.
890 Overexpression of PEAK1 contributes to epithelial-mesenchymal transition and tumor metastasis in lung cancer through modulating ERK1/2 and JAK2 signaling.Cell Death Dis. 2018 Jul 23;9(8):802. doi: 10.1038/s41419-018-0817-1.
891 Alterative Expression and Localization of Profilin 1/VASPpS157 and Cofilin 1/VASPpS239 Regulates Metastatic Growth and Is Modified by DHA Supplementation.Mol Cancer Ther. 2016 Sep;15(9):2220-31. doi: 10.1158/1535-7163.MCT-16-0092. Epub 2016 Aug 5.
892 Class II phosphoinositide 3-kinase C2 regulates a novel signaling pathway involved in breast cancer progression.Oncotarget. 2016 Apr 5;7(14):18325-45. doi: 10.18632/oncotarget.7761.
893 Phosphatidylinositol transfer protein- in platelets is inconsequential for thrombosis yet is utilized for tumor metastasis.Nat Commun. 2017 Oct 31;8(1):1216. doi: 10.1038/s41467-017-01181-4.
894 PLA2G16 Expression in Human Osteosarcoma Is Associated with Pulmonary Metastasis and Poor Prognosis.PLoS One. 2015 May 18;10(5):e0127236. doi: 10.1371/journal.pone.0127236. eCollection 2015.
895 PLAGL1 (ZAC1/LOT1) Expression in Clear Cell Renal Cell Carcinoma: Correlations with Disease Progression and Unfavorable Prognosis.Anticancer Res. 2016 Feb;36(2):617-24.
896 Polo-like kinase 3 and phosphoT273 caspase-8 are associated with improved local tumor control and survival in patients with anal carcinoma treated with concomitant chemoradiotherapy.Oncotarget. 2016 Aug 16;7(33):53339-53349. doi: 10.18632/oncotarget.10801.
897 Reduced NOV expression correlates with disease progression in colorectal cancer and is associated with survival, invasion and chemoresistance of cancer cells.Oncotarget. 2017 Apr 18;8(16):26231-26244. doi: 10.18632/oncotarget.15439.
898 miR?9a?p targets PMEPA1 and induces prostate cancer cell proliferation, migration and invasion.Mol Med Rep. 2016 May;13(5):4030-8. doi: 10.3892/mmr.2016.5033. Epub 2016 Mar 21.
899 Podocalyxin enhances breast tumor growth and metastasis and is a target for monoclonal antibody therapy.Breast Cancer Res. 2015 Mar 27;17(1):46. doi: 10.1186/s13058-015-0562-7.
900 CDC2/CDK1 expression in esophageal adenocarcinoma and precursor lesions serves as a diagnostic and cancer progression marker and potential novel drug target.Am J Surg Pathol. 2005 Mar;29(3):390-9. doi: 10.1097/00000478-200503000-00014.
901 The role of double-strand break repair, translesion synthesis, and interstrand crosslinks in colorectal cancer progression-clinicopathological data and survival.J Surg Oncol. 2020 Apr;121(5):906-916. doi: 10.1002/jso.25737. Epub 2019 Oct 25.
902 POU2F2-oriented network promotes human gastric cancer metastasis.Gut. 2016 Sep;65(9):1427-38. doi: 10.1136/gutjnl-2014-308932. Epub 2015 May 27.
903 LncRNA POU3F3 promotes cancer cell migration and invasion in nasopharyngeal carcinoma by up-regulating TGF-1.Biosci Rep. 2019 Jan 25;39(1):BSR20181632. doi: 10.1042/BSR20181632. Print 2019 Jan 31.
904 Colorectal Cancer Genetic Heterogeneity Delineated by Multi-Region Sequencing.PLoS One. 2016 Mar 29;11(3):e0152673. doi: 10.1371/journal.pone.0152673. eCollection 2016.
905 Can PPH3 be helpful to assess the discordant grade in primary and metastatic enteropancreatic neuroendocrine tumors?.Endocrine. 2016 Aug;53(2):395-401. doi: 10.1007/s12020-016-0944-3. Epub 2016 Apr 5.
906 Overexpression of long noncoding RNA, NEAT1 promotes cell proliferation, invasion and migration in endometrial endometrioid adenocarcinoma.Biomed Pharmacother. 2016 Dec;84:244-251. doi: 10.1016/j.biopha.2016.09.008. Epub 2016 Sep 21.
907 Peroxiredoxin-1 promotes cell proliferation and metastasis through enhancing Akt/mTOR in human osteosarcoma cells.Oncotarget. 2017 Dec 23;9(9):8290-8302. doi: 10.18632/oncotarget.23662. eCollection 2018 Feb 2.
908 Integrative analysis of h-prune as a potential therapeutic target for hepatocellular carcinoma.EBioMedicine. 2019 Mar;41:310-319. doi: 10.1016/j.ebiom.2019.01.001. Epub 2019 Jan 18.
909 Assessment of long-term risks of secondary cancer in paediatric patients with brain tumours after boron neutron capture therapy.J Radiol Prot. 2019 Sep;39(3):838-853. doi: 10.1088/1361-6498/ab29a3. Epub 2019 Jun 13.
910 Potential Implication of Paxillin in Cancer Establishment Within the Bone Environment.Anticancer Res. 2017 Aug;37(8):4255-4268. doi: 10.21873/anticanres.11818.
911 VAMP8, a vesicle-SNARE required for RAB37-mediated exocytosis, possesses a tumor metastasis suppressor function.Cancer Lett. 2018 Nov 28;437:79-88. doi: 10.1016/j.canlet.2018.08.023. Epub 2018 Aug 27.
912 High expression of small GTPase Rab3D promotes cancer progression and metastasis.Oncotarget. 2015 May 10;6(13):11125-38. doi: 10.18632/oncotarget.3575.
913 Reduced RanBPM Expression Is Associated with Distant Metastasis in Gastric Cancer and Chemoresistance.Anticancer Res. 2016 Mar;36(3):1295-303.
914 MiR-496 promotes migration and epithelial-mesenchymal transition by targeting RASSF6 in colorectal cancer.J Cell Physiol. 2020 Feb;235(2):1469-1479. doi: 10.1002/jcp.29066. Epub 2019 Jul 4.
915 Regulating RNA Binding Motif 5 Gene Expression- A Novel Therapeutic Target for Lung Cancer.J Environ Pathol Toxicol Oncol. 2017;36(2):99-105. doi: 10.1615/JEnvironPatholToxicolOncol.2017019366.
916 RCC2 promotes proliferation and radio-resistance in glioblastoma via activating transcription of DNMT1.Biochem Biophys Res Commun. 2019 Aug 27;516(3):999-1006. doi: 10.1016/j.bbrc.2019.06.097. Epub 2019 Jul 2.
917 Elevated circulating macrophage inhibitory cytokine 1 is a biological marker for the diagnosis and prognosis of osteosarcoma.Exp Ther Med. 2018 Dec;16(6):4803-4809. doi: 10.3892/etm.2018.6786. Epub 2018 Sep 21.
918 Pathophysiological Functions of Rnd3/RhoE.Compr Physiol. 2015 Dec 15;6(1):169-86. doi: 10.1002/cphy.c150018.
919 Ribosomal protein S15A promotes malignant transformation and predicts poor outcome in colorectal cancer through misregulation of p53 signaling pathway.Int J Oncol. 2016 Apr;48(4):1628-38. doi: 10.3892/ijo.2016.3366. Epub 2016 Feb 1.
920 RSPO2 suppresses colorectal cancer metastasis by counteracting the Wnt5a/Fzd7-driven noncanonical Wnt pathway.Cancer Lett. 2017 Aug 28;402:153-165. doi: 10.1016/j.canlet.2017.05.024. Epub 2017 Jun 6.
921 Proteomics analysis of melanoma metastases: association between S100A13 expression and chemotherapy resistance.Br J Cancer. 2014 May 13;110(10):2489-95. doi: 10.1038/bjc.2014.169. Epub 2014 Apr 10.
922 SALL4 as an Epithelial-Mesenchymal Transition and Drug Resistance Inducer through the Regulation of c-Myc in Endometrial Cancer.PLoS One. 2015 Sep 25;10(9):e0138515. doi: 10.1371/journal.pone.0138515. eCollection 2015.
923 MiRNA-139-3p inhibits the proliferation, invasion, and migration of human glioma cells by targeting MDA-9/syntenin.Biochem Biophys Res Commun. 2019 Jan 1;508(1):295-301. doi: 10.1016/j.bbrc.2018.11.144. Epub 2018 Nov 27.
924 Molecular Subtypes of KIT/PDGFRA Wild-Type Gastrointestinal Stromal Tumors: A Report From the National Institutes of Health Gastrointestinal Stromal Tumor Clinic.JAMA Oncol. 2016 Jul 1;2(7):922-8. doi: 10.1001/jamaoncol.2016.0256.
925 The axon guidance molecule semaphorin 3F is a negative regulator of tumor progression and proliferation in ileal neuroendocrine tumors.Oncotarget. 2015 Nov 3;6(34):36731-45. doi: 10.18632/oncotarget.5481.
926 Semaphorin 7a exerts pleiotropic effects to promote breast tumor progression.Oncogene. 2016 Sep 29;35(39):5170-8. doi: 10.1038/onc.2016.49. Epub 2016 Apr 11.
927 Dual-faced SH3BGRL: oncogenic in mice, tumor suppressive in humans.Oncogene. 2016 Jun 23;35(25):3303-13. doi: 10.1038/onc.2015.391. Epub 2015 Oct 12.
928 Tumour-suppressive function of SIRT4 in human colorectal cancer.Br J Cancer. 2015 Jul 28;113(3):492-9. doi: 10.1038/bjc.2015.226. Epub 2015 Jun 18.
929 SMC1A promotes growth and migration of prostate cancer in vitro and in vivo.Int J Oncol. 2016 Nov;49(5):1963-1972. doi: 10.3892/ijo.2016.3697. Epub 2016 Sep 19.
930 Overexpression of SMOC2 Attenuates the Tumorigenicity of Hepatocellular Carcinoma Cells and Is Associated With a Positive Postoperative Prognosis in Human Hepatocellular Carcinoma.J Cancer. 2017 Oct 17;8(18):3812-3827. doi: 10.7150/jca.20775. eCollection 2017.
931 Treatment of a glioblastoma multiforme dural metastasis with stereotactic radiosurgery: A case report and select review of the literature.J Clin Neurosci. 2018 Feb;48:118-121. doi: 10.1016/j.jocn.2017.11.003. Epub 2017 Nov 26.
932 The suppressor of cytokine signaling 2 (SOCS2) inhibits tumor metastasis in hepatocellular carcinoma.Tumour Biol. 2016 Oct;37(10):13521-13531. doi: 10.1007/s13277-016-5215-7. Epub 2016 Jul 28.
933 Sohlh2 inhibits human ovarian cancer cell invasion and metastasis by transcriptional inactivation of MMP9.Mol Carcinog. 2016 Jul;55(7):1127-37. doi: 10.1002/mc.22355. Epub 2015 Jul 8.
934 Cancer Testis Antigen Promotes Triple Negative Breast Cancer Metastasis and is Traceable in the Circulating Extracellular Vesicles.Sci Rep. 2019 Aug 12;9(1):11632. doi: 10.1038/s41598-019-48064-w.
935 Downregulation of Sprouty homolog2 by microRNA-21 inhibits proliferation, metastasis and invasion, however promotes the apoptosis of multiple myeloma cells.Mol Med Rep. 2015 Aug;12(2):1810-6. doi: 10.3892/mmr.2015.3567. Epub 2015 Mar 30.
936 Slit-Robo GTPase-Activating Protein 2 as a metastasis suppressor in osteosarcoma.Sci Rep. 2016 Dec 14;6:39059. doi: 10.1038/srep39059.
937 Which patients with ES-SCLC are most likely to benefit from more aggressive radiotherapy: A secondary analysis of the Phase III CREST trial.Lung Cancer. 2017 Jun;108:150-153. doi: 10.1016/j.lungcan.2017.03.007. Epub 2017 Mar 21.
938 Knockdown of ST6Gal-I increases cisplatin sensitivity in cervical cancer cells.BMC Cancer. 2016 Dec 16;16(1):949. doi: 10.1186/s12885-016-2981-y.
939 GSK3 controls epithelial-mesenchymal transition and tumor metastasis by CHIP-mediated degradation of Slug.Oncogene. 2017 Oct 19;36(42):5916. doi: 10.1038/onc.2017.302. Epub 2017 Sep 4.
940 Pulmonary Metastases Exhibit Epigenetic Clonality: Implications for Precision Cancer Therapy.Ann Thorac Surg. 2015 Nov;100(5):1839-48; discussion 1848. doi: 10.1016/j.athoracsur.2015.05.089. Epub 2015 Aug 20.
941 Hypermethylation of TET1 promoter is a new diagnosic marker for breast cancer metastasis.Asian Pac J Cancer Prev. 2015;16(3):1197-200. doi: 10.7314/apjcp.2015.16.3.1197.
942 Transforming growth factor beta-induced (TGFBI) is an anti-adhesive protein regulating the invasive growth of melanoma cells.Am J Pathol. 2012 Apr;180(4):1663-74. doi: 10.1016/j.ajpath.2011.12.035. Epub 2012 Feb 9.
943 Thrombospondin 2 promotes tumor metastasis by inducing matrix metalloproteinase-13 production in lung cancer cells.Biochem Pharmacol. 2018 Sep;155:537-546. doi: 10.1016/j.bcp.2018.07.024. Epub 2018 Jul 20.
944 Expression of metastasis suppressor gene AES driven by a Yin Yang (YY) element in a CpG island promoter and transcription factor YY2.Cancer Sci. 2016 Nov;107(11):1622-1631. doi: 10.1111/cas.13063.
945 Down-regulation of C12orf59 is associated with a poor prognosis and VHL mutations in renal cell carcinoma.Oncotarget. 2016 Feb 9;7(6):6824-34. doi: 10.18632/oncotarget.6829.
946 Tumor Metabolism in the Microenvironment of Nodal Metastasis in Oral Squamous Cell Carcinoma.Otolaryngol Head Neck Surg. 2017 Nov;157(5):798-807. doi: 10.1177/0194599817709224. Epub 2017 Jun 13.
947 The c.*229C?T gene polymorphism in 3'UTR region of the topoisomerase II binding protein 1 gene and LOH in BRCA1/2 regions and their effect on the risk and progression of human laryngeal carcinoma.Tumour Biol. 2016 Apr;37(4):4541-57. doi: 10.1007/s13277-015-4276-3. Epub 2015 Oct 27.
948 Tumor protein D52 (isoform 3) contributes to prostate cancer cell growth via targeting nuclear factor-B transactivation in LNCaP cells.Tumour Biol. 2017 May;39(5):1010428317698382. doi: 10.1177/1010428317698382.
949 Tropomyosin-1 Functions as a Tumor Suppressor with Respect to Cell Proliferation, Angiogenesis and Metastasis in Renal Cell Carcinoma.J Cancer. 2019 May 21;10(10):2220-2228. doi: 10.7150/jca.28261. eCollection 2019.
950 Tripartite motif 16 inhibits epithelial-mesenchymal transition and metastasis by down-regulating sonic hedgehog pathway in non-small cell lung cancer cells.Biochem Biophys Res Commun. 2015 May 15;460(4):1021-8. doi: 10.1016/j.bbrc.2015.03.144. Epub 2015 Apr 2.
951 All Paths Lead to TRIM25.Trends Cancer. 2017 Oct;3(10):673-675. doi: 10.1016/j.trecan.2017.08.005.
952 Tripartite motif-containing 3 (TRIM3) inhibits tumor growth and metastasis of liver cancer.Chin J Cancer. 2017 Sep 26;36(1):77. doi: 10.1186/s40880-017-0240-5.
953 Tripartite motif containing 62 is a novel prognostic marker and suppresses tumor metastasis via c-Jun/Slug signaling-mediated epithelial-mesenchymal transition in cervical cancer.J Exp Clin Cancer Res. 2016 Oct 28;35(1):170. doi: 10.1186/s13046-016-0445-5.
954 Tspan2: a tetraspanin protein involved in oligodendrogenesis and cancer metastasis.Biochem Soc Trans. 2017 Apr 15;45(2):465-475. doi: 10.1042/BST20160022.
955 Tspan9 inhibits the proliferation, migration and invasion of human gastric cancer SGC7901 cells via the ERK1/2 pathway.Oncol Rep. 2016 Jul;36(1):448-54. doi: 10.3892/or.2016.4805. Epub 2016 May 13.
956 In situ hybridization studies of alpha 2-macroglobulin receptor and receptor-associated protein in human prostate carcinoma.Prostate. 1996 May;28(5):311-7. doi: 10.1002/(SICI)1097-0045(199605)28:5<311::AID-PROS7>3.0.CO;2-E.
957 Localization of sporadic neuroendocrine tumors by gene expression analysis of their metastases.Clin Exp Metastasis. 2011 Oct;28(7):637-47. doi: 10.1007/s10585-011-9397-5. Epub 2011 Jun 17.
958 Expression of Abelson interactor 1 (Abi1) correlates with inflammation, KRAS mutation and adenomatous change during colonic carcinogenesis.PLoS One. 2012;7(7):e40671. doi: 10.1371/journal.pone.0040671. Epub 2012 Jul 10.
959 Forced expression of NESH suppresses motility and metastatic dissemination of malignant cells.Cancer Res. 2002 Apr 15;62(8):2215-9.
960 Identification of ACTG2 functions as a promoter gene in hepatocellular carcinoma cells migration and tumor metastasis.Biochem Biophys Res Commun. 2017 Sep 16;491(2):537-544. doi: 10.1016/j.bbrc.2017.04.007. Epub 2017 Apr 4.
961 ADAM23 methylation and expression analysis in brain tumors.Neurosci Lett. 2005 Jun 3;380(3):260-4. doi: 10.1016/j.neulet.2005.01.050. Epub 2005 Feb 8.
962 Potential markers of tongue tumor progression selected by cDNA microarray.Int J Immunopathol Pharmacol. 2005 Jul-Sep;18(3):513-24. doi: 10.1177/039463200501800311.
963 The epigenetic factor BORIS (CTCFL) controls the androgen receptor regulatory network in ovarian cancer.Oncogenesis. 2019 Aug 12;8(8):41. doi: 10.1038/s41389-019-0150-2.
964 Anterior gradient 2 and 3--two prototype androgen-responsive genes transcriptionally upregulated by androgens and by oestrogens in prostate cancer cells.FEBS J. 2013 Mar;280(5):1249-66. doi: 10.1111/febs.12118. Epub 2013 Feb 13.
965 Doxorubicin resistance in breast cancer: A novel role for the human protein AHNAK.Biochem Pharmacol. 2018 Feb;148:174-183. doi: 10.1016/j.bcp.2018.01.012. Epub 2018 Jan 5.
966 Kisspeptin effect on endothelial monocyte activating polypeptide II (EMAP-II)-associated lymphocyte cell death and metastases in colorectal cancer patients.Mol Med. 2014 Mar 18;20(1):80-92. doi: 10.2119/molmed.2013.00151.
967 Blood type B antigen modulates cell migration through regulating cdc42 expression and activity in HaCaT cells.J Cell Physiol. 2013 Nov;228(11):2243-51. doi: 10.1002/jcp.24393.
968 Suppression of urokinase expression and tumor metastasis by bikunin overexpression [mini-review].Hum Cell. 2001 Sep;14(3):233-6.
969 Angiopoietin-3 inhibits pulmonary metastasis by inhibiting tumor angiogenesis.Cancer Res. 2004 Sep 1;64(17):6119-26. doi: 10.1158/0008-5472.CAN-04-1054.
970 Serum Angiopoietin-like Protein 2 Improves Preoperative Detection of Lymph Node Metastasis in Colorectal Cancer.Anticancer Res. 2015 May;35(5):2849-56.
971 ANKHD1 is required for SMYD3 to promote tumor metastasis in hepatocellular carcinoma.J Exp Clin Cancer Res. 2019 Jan 15;38(1):18. doi: 10.1186/s13046-018-1011-0.
972 Preferential expression of NY-BR-1 and GATA-3 in male breast cancer.J Cancer Res Clin Oncol. 2018 Feb;144(2):199-204. doi: 10.1007/s00432-017-2542-z. Epub 2017 Nov 7.
973 Single-chain antigen recognition receptors that costimulate potent rejection of established experimental tumors.Blood. 2002 Nov 1;100(9):3155-63. doi: 10.1182/blood-2002-04-1041.
974 Amyloid precursor-like protein 1 is differentially upregulated in neuroendocrine tumours of the gastrointestinal tract.Endocr Relat Cancer. 2008 Jun;15(2):569-81. doi: 10.1677/ERC-07-0145. Epub 2008 Apr 22.
975 Amyloid precursor-like protein 2 (APLP2) affects the actin cytoskeleton and increases pancreatic cancer growth and metastasis.Oncotarget. 2015 Feb 10;6(4):2064-75. doi: 10.18632/oncotarget.2990.
976 IGF2BP3-mediated translation in cell protrusions promotes cell invasiveness and metastasis of pancreatic cancer.Oncotarget. 2014 Aug 30;5(16):6832-45. doi: 10.18632/oncotarget.2257.
977 ARID4B is a good biomarker to predict tumour behaviour and decide WHO grades in gliomas and meningiomas.J Clin Pathol. 2017 Feb;70(2):162-167. doi: 10.1136/jclinpath-2016-203804. Epub 2016 Jul 22.
978 JWA suppresses tumor angiogenesis via Sp1-activated matrix metalloproteinase-2 and its prognostic significance in human gastric cancer.Carcinogenesis. 2014 Feb;35(2):442-51. doi: 10.1093/carcin/bgt311. Epub 2013 Sep 26.
979 Down-regulation of ARNT promotes cancer metastasis by activating the fibronectin/integrin 1/FAK axis.Oncotarget. 2015 May 10;6(13):11530-46. doi: 10.18632/oncotarget.3448.
980 Cell motility is controlled by SF2/ASF through alternative splicing of the Ron protooncogene.Mol Cell. 2005 Dec 22;20(6):881-90. doi: 10.1016/j.molcel.2005.10.026.
981 miR-223 regulates migration and invasion by targeting Artemin in human esophageal carcinoma.J Biomed Sci. 2011 Mar 31;18(1):24. doi: 10.1186/1423-0127-18-24.
982 Overexpression of beta 1,4N-acetylgalactosaminyl- transferase mRNA as a molecular marker for various types of cancers.Oncology. 2002;62(2):149-56. doi: 10.1159/000048261.
983 A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential.Gastroenterology. 2009 Jul;137(1):165-75. doi: 10.1053/j.gastro.2009.03.041. Epub 2009 Mar 26.
984 p53 target gene SMAR1 is dysregulated in breast cancer: its role in cancer cell migration and invasion.PLoS One. 2007 Aug 1;2(7):e660. doi: 10.1371/journal.pone.0000660.
985 Decreased SARI expression predicts poor prognosis of Chinese patients with non-small cell lung cancer.Int J Clin Exp Pathol. 2013 Sep 15;6(10):2056-63. eCollection 2013.
986 Genetic and epigenetic silencing of SCARA5 may contribute to human hepatocellular carcinoma by activating FAK signaling.J Clin Invest. 2010 Jan;120(1):223-41. doi: 10.1172/JCI38012. Epub 2009 Dec 14.
987 BCL2L12 is a novel biomarker for the prediction of short-term relapse in nasopharyngeal carcinoma.Mol Med. 2011 Mar-Apr;17(3-4):163-71. doi: 10.2119/molmed.2010.00056. Epub 2010 Dec 8.
988 A Rationally Optimized Nanoparticle System for the Delivery of RNA Interference Therapeutics into Pancreatic Tumors in Vivo.Biomacromolecules. 2016 Jul 11;17(7):2337-51. doi: 10.1021/acs.biomac.6b00185. Epub 2016 Jun 28.
989 BOK displays cell death-independent tumor suppressor activity in non-small-cell lung carcinoma.Int J Cancer. 2017 Nov 15;141(10):2050-2061. doi: 10.1002/ijc.30906. Epub 2017 Aug 7.
990 Significance of BRCA1 expression in breast and ovarian cancer patients with brain metastasis - A multicentre study.Adv Med Sci. 2019 Sep;64(2):235-240. doi: 10.1016/j.advms.2018.12.007. Epub 2019 Feb 26.
991 BRMS1L suppresses ovarian cancer metastasis via inhibition of the -catenin-wnt pathway.Exp Cell Res. 2018 Oct 1;371(1):214-221. doi: 10.1016/j.yexcr.2018.08.013. Epub 2018 Aug 15.
992 Clinicopathological significance of BTF3 expression in colorectal cancer.Tumour Biol. 2013 Aug;34(4):2141-6. doi: 10.1007/s13277-013-0745-8. Epub 2013 Mar 27.
993 Associations among beta-TrCP, an E3 ubiquitin ligase receptor, beta-catenin, and NF-kappaB in colorectal cancer.J Natl Cancer Inst. 2004 Aug 4;96(15):1161-70. doi: 10.1093/jnci/djh219.
994 Genetic and epigenetic inactivation of mitotic checkpoint genes hBUB1 and hBUBR1 and their relationship to survival.Cancer Res. 2002 Jan 1;62(1):13-7.
995 Nm23-H1 suppresses metastasis by inhibiting expression of the lysophosphatidic acid receptor EDG2.Cancer Res. 2007 Dec 15;67(24):11751-9. doi: 10.1158/0008-5472.CAN-07-3175.
996 Identification of calretinin and the alternatively spliced form calretinin-22k in primary pleural mesotheliomas and in their metastases.Anticancer Res. 2004 Nov-Dec;24(6):4003-9.
997 Overexpression of caldesmon is associated with lymph node metastasis and poorer prognosis in patients with oral cavity squamous cell carcinoma.Cancer. 2013 Nov 15;119(22):4003-11. doi: 10.1002/cncr.28300. Epub 2013 Aug 20.
998 L-CAM expression in lymph node and liver metastases of colorectal carcinomas.J Pathol. 1994 Feb;172(2):177-81. doi: 10.1002/path.1711720204.
999 HP1 suppresses metastasis of human cancer cells by decreasing the expression and activation of MMP2.Int J Oncol. 2014 Dec;45(6):2541-8. doi: 10.3892/ijo.2014.2646. Epub 2014 Sep 9.
1000 Loss of SMAD4 Promotes Lung Metastasis of Colorectal Cancer by Accumulation of CCR1+ Tumor-Associated Neutrophils through CCL15-CCR1 Axis.Clin Cancer Res. 2017 Feb 1;23(3):833-844. doi: 10.1158/1078-0432.CCR-16-0520. Epub 2016 Aug 4.
1001 Positive expression of chemokine (C-C Motif) ligand 18 and prognosis in cancer: A meta-analysis.J BUON. 2018 Jul-Aug;23(4):1185-1194.
1002 CCR7 mediates human breast cancer cell invasion, migration by inducing epithelial-mesenchymal transition and suppressing apoptosis through AKT pathway.Cancer Med. 2017 May;6(5):1062-1071. doi: 10.1002/cam4.1039. Epub 2017 Apr 4.
1003 Differential expression and prognostic implications of the CCN family members WISP-1, WISP-2, and WISP-3 in human breast cancer.Ann Surg Oncol. 2007 Jun;14(6):1909-18. doi: 10.1245/s10434-007-9376-x. Epub 2007 Apr 4.
1004 Establishing a detection method for CCNY: a potentially significant clinical investigative marker in NSCLC patients.Onco Targets Ther. 2019 Jan 29;12:921-932. doi: 10.2147/OTT.S180507. eCollection 2019.
1005 Tumour-infiltrating neutrophils counteract anti-VEGF therapy in metastatic colorectal cancer.Br J Cancer. 2019 Jan;120(1):69-78. doi: 10.1038/s41416-018-0198-3. Epub 2018 Oct 31.
1006 The search for the primary tumor in metastasized gastroenteropancreatic neuroendocrine neoplasm.Clin Exp Metastasis. 2014 Oct;31(7):817-27. doi: 10.1007/s10585-014-9672-3. Epub 2014 Aug 7.
1007 The pattern of cytokine gene expression in freshly excised human metastatic melanoma suggests a state of reversible anergy of tumor-infiltrating lymphocytes.Int J Cancer. 1994 May 15;57(4):612-9. doi: 10.1002/ijc.2910570428.
1008 CD82, and CD63 in thyroid cancer.Int J Mol Med. 2004 Oct;14(4):517-27.
1009 Redox state of adipose tissue for patients with gastric cancer and its connection with the body mass index and distance from the tumor.Obes Res Clin Pract. 2020 Jan-Feb;14(1):34-38. doi: 10.1016/j.orcp.2019.10.003. Epub 2019 Nov 9.
1010 Homophilic complex formation of CDCP1 via the extracellular CUB2 domain facilitates SFK activation and promotes cancer cell migration.Oncol Rep. 2019 Oct;42(4):1507-1516. doi: 10.3892/or.2019.7271. Epub 2019 Aug 8.
1011 Knockdown of liver-intestine cadherin decreases BGC823 cell invasiveness and metastasis in vivo.World J Gastroenterol. 2012 Jun 28;18(24):3129-37. doi: 10.3748/wjg.v18.i24.3129.
1012 Promoter-associated endogenous and exogenous small RNAs suppress human bladder cancer cell metastasis by activating p21 (CIP1/WAF1) expression.Tumour Biol. 2016 May;37(5):6589-98. doi: 10.1007/s13277-015-4571-z. Epub 2015 Dec 7.
1013 ADAM12 transmembrane and secreted isoforms promote breast tumor growth: a distinct role for ADAM12-S protein in tumor metastasis.J Biol Chem. 2011 Jun 10;286(23):20758-68. doi: 10.1074/jbc.M110.216036. Epub 2011 Apr 14.
1014 C/EBP links IL-6 and HIF-1 signaling to promote breast cancer stem cell-associated phenotypes.Oncogene. 2019 May;38(20):3765-3780. doi: 10.1038/s41388-018-0516-5. Epub 2018 Sep 27.
1015 Alteration in gene expression profile and biological behavior in human lung cancer cell line NL9980 by nm23-H1 gene silencing.Biochem Biophys Res Commun. 2008 Jul 4;371(3):425-30. doi: 10.1016/j.bbrc.2008.04.083. Epub 2008 Apr 25.
1016 Analysis of tumor progression by transcriptional profiling of mouse MK16 cell lines transformed with human papillomavirus type 16 E6 and E7 oncogenes and activated H-ras.Oncol Rep. 2005 Dec;14(6):1665-74.
1017 p150 overexpression in gastric carcinoma: the association with p53, apoptosis and cell proliferation.Int J Cancer. 2004 Nov 10;112(3):393-8. doi: 10.1002/ijc.20443.
1018 Overexpression of CHD1L is positively associated with metastasis of lung adenocarcinoma and predicts patients poor survival.Oncotarget. 2015 Oct 13;6(31):31181-90. doi: 10.18632/oncotarget.5070.
1019 CHD4 Has Oncogenic Functions in Initiating and Maintaining Epigenetic Suppression of Multiple Tumor Suppressor Genes.Cancer Cell. 2017 May 8;31(5):653-668.e7. doi: 10.1016/j.ccell.2017.04.005.
1020 Suppression of metastasis through inhibition of chitinase 3-like 1 expression by miR-125a-3p-mediated up-regulation of USF1.Theranostics. 2018 Aug 7;8(16):4409-4428. doi: 10.7150/thno.26467. eCollection 2018.
1021 CDC28 protein kinase regulatory subunit 1B (CKS1B) expression and genetic status analysis in oral squamous cell carcinoma.Histol Histopathol. 2011 Jan;26(1):71-7. doi: 10.14670/HH-26.71.
1022 Cyclin-Dependent Kinase Regulatory Subunit 2 Indicated Poor Prognosis and Facilitated Aggressive Phenotype of Hepatocellular Carcinoma.Dis Markers. 2019 Oct 22;2019:8964015. doi: 10.1155/2019/8964015. eCollection 2019.
1023 Gene trapping identifies chloride channel 4 as a novel inducer of colon cancer cell migration, invasion and metastases.Br J Cancer. 2010 Feb 16;102(4):774-82. doi: 10.1038/sj.bjc.6605536. Epub 2010 Jan 19.
1024 Distinct presence of the tight junction protein claudin-3 in olfactory bulb and fila olfactoria of the mouse.Histol Histopathol. 2017 Aug;32(8):835-849. doi: 10.14670/HH-11-854. Epub 2016 Dec 12.
1025 Functional characterization of recombinant snake venom rhodocytin: rhodocytin mutant blocks CLEC-2/podoplanin-dependent platelet aggregation and lung metastasis.J Thromb Haemost. 2018 May;16(5):960-972. doi: 10.1111/jth.13987. Epub 2018 Mar 30.
1026 Increasing Incidence of Colon Cancer in the Young: Assessing the Tumor Biology.J Am Coll Surg. 2019 Jul;229(1):79-90. doi: 10.1016/j.jamcollsurg.2019.03.022. Epub 2019 Apr 14.
1027 Coronin 3 promotes gastric cancer metastasis via the up-regulation of MMP-9 and cathepsin K.Mol Cancer. 2012 Sep 14;11:67. doi: 10.1186/1476-4598-11-67.
1028 Differential expression of PAI-RBP1, C1orf142, and COTL1 in non-small cell lung cancer cell lines with different tumor metastatic potential.J Investig Med. 2012 Apr;60(4):689-94. doi: 10.2310/JIM.0b013e31824963b6.
1029 CPEB4 promotes cell migration and invasion via upregulating Vimentin expression in breast cancer.Biochem Biophys Res Commun. 2017 Jul 22;489(2):135-141. doi: 10.1016/j.bbrc.2017.05.112. Epub 2017 May 20.
1030 Low expression of cyclic AMP response element modulator-1 can increase the migration and invasion of esophageal squamous cell carcinoma.Tumour Biol. 2013 Dec;34(6):3649-57. doi: 10.1007/s13277-013-0946-1. Epub 2013 Aug 9.
1031 The impact of cysteine-rich intestinal protein 1 (CRIP1) in human breast cancer.Mol Cancer. 2013 Apr 9;12:28. doi: 10.1186/1476-4598-12-28.
1032 Effect of androgen deprivation therapy on the expression of prostate cancer biomarkers MSMB and MSMB-binding protein CRISP3.Prostate Cancer Prostatic Dis. 2010 Dec;13(4):369-75. doi: 10.1038/pcan.2010.25. Epub 2010 Aug 3.
1033 miR-429 suppresses tumor migration and invasion by targeting CRKL in hepatocellular carcinoma via inhibiting Raf/MEK/ERK pathway and epithelial-mesenchymal transition.Sci Rep. 2018 Feb 5;8(1):2375. doi: 10.1038/s41598-018-20258-8.
1034 Molecular genetic analysis of malignant melanomas for aberrations of the WNT signaling pathway genes CTNNB1, APC, ICAT and BTRC.Int J Cancer. 2002 Aug 10;100(5):549-56. doi: 10.1002/ijc.10512.
1035 Overexpression and Tyr421-phosphorylation of cortactin is induced by three-dimensional spheroid culturing and contributes to migration and invasion of pancreatic ductal adenocarcinoma (PDAC) cells.Cancer Cell Int. 2019 Mar 29;19:77. doi: 10.1186/s12935-019-0798-x. eCollection 2019.
1036 CXCR6 upregulation contributes to a proinflammatory tumor microenvironment that drives metastasis and poor patient outcomes in hepatocellular carcinoma.Cancer Res. 2012 Jul 15;72(14):3546-56. doi: 10.1158/0008-5472.CAN-11-4032. Epub 2012 Jun 18.
1037 CXCL17 expression by tumor cells recruits CD11b+Gr1 high F4/80- cells and promotes tumor progression.PLoS One. 2012;7(8):e44080. doi: 10.1371/journal.pone.0044080. Epub 2012 Aug 29.
1038 Apoptosis-induced CXCL5 accelerates inflammation and growth of prostate tumor metastases in bone.J Clin Invest. 2018 Jan 2;128(1):248-266. doi: 10.1172/JCI92466. Epub 2017 Nov 27.
1039 Isotypic neutralizing antibodies against mouse GCP-2/CXCL6 inhibit melanoma growth and metastasis.Cancer Lett. 2011 Mar 1;302(1):54-62. doi: 10.1016/j.canlet.2010.12.013. Epub 2011 Jan 13.
1040 Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis.Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2485-90. doi: 10.1073/pnas.0908133107. Epub 2010 Jan 13.
1041 Dapper homolog 1 is a novel tumor suppressor in gastric cancer through inhibiting the nuclear factor-B signaling pathway.Mol Med. 2012 Dec 20;18(1):1402-11. doi: 10.2119/molmed.2012.00243.
1042 DAP1 high expression increases risk of lymph node metastases in squamous cell carcinoma of the oral cavity.Genet Mol Res. 2015 Sep 8;14(3):10515-23. doi: 10.4238/2015.September.8.13.
1043 Mesenchymal stem cells as a vehicle for targeted delivery of CRAds to lung metastases of breast carcinoma.Breast Cancer Res Treat. 2007 Oct;105(2):157-67. doi: 10.1007/s10549-006-9449-8. Epub 2007 Jan 13.
1044 Cytoplasmic p27 promotes epithelial-mesenchymal transition and tumor metastasis via STAT3-mediated Twist1 upregulation.Oncogene. 2015 Oct;34(43):5447-59. doi: 10.1038/onc.2014.473. Epub 2015 Feb 16.
1045 DCUN1D1 facilitates tumor metastasis by activating FAK signaling and up-regulates PD-L1 in non-small-cell lung cancer.Exp Cell Res. 2019 Jan 15;374(2):304-314. doi: 10.1016/j.yexcr.2018.12.001. Epub 2018 Dec 4.
1046 The prognostic effect of DDX3 upregulation in distant breast cancer metastases.Clin Exp Metastasis. 2017 Jan;34(1):85-92. doi: 10.1007/s10585-016-9832-8. Epub 2016 Dec 20.
1047 Deleterious synergistic effects of distress and surgery on cancer metastasis: Abolishment through an integrated perioperative immune-stimulating stress-inflammatory-reducing intervention.Brain Behav Immun. 2019 Aug;80:170-178. doi: 10.1016/j.bbi.2019.03.005. Epub 2019 Mar 6.
1048 The genomic relationship between primary breast carcinomas and their nodal metastases.Cancer Invest. 2011 May;29(4):300-7. doi: 10.3109/07357907.2011.568564.
1049 Cell adhesion molecules in metastatic neuroblastoma models.Clin Exp Metastasis. 2014 Apr;31(4):483-96. doi: 10.1007/s10585-014-9643-8. Epub 2014 Feb 19.
1050 Comprehensive models of human primary and metastatic colorectal tumors in immunodeficient and immunocompetent mice by chemokine targeting.Nat Biotechnol. 2015 Jun;33(6):656-60. doi: 10.1038/nbt.3239. Epub 2015 May 25.
1051 Genetic determinants of methotrexate responsiveness and resistance in colon cancer cells.Oncogene. 2005 Oct 13;24(45):6842-7. doi: 10.1038/sj.onc.1208834.
1052 DLC-1 expression levels in breast cancer assessed by qRT- PCR are negatively associated with malignancy.Asian Pac J Cancer Prev. 2012;13(4):1231-3. doi: 10.7314/apjcp.2012.13.4.1231.
1053 Mutually exclusive expression of DLX2 and DLX5/6 is associated with the metastatic potential of the human breast cancer cell line MDA-MB-231.BMC Cancer. 2010 Nov 25;10:649. doi: 10.1186/1471-2407-10-649.
1054 Tid1 negatively regulates the migratory potential of cancer cells by inhibiting the production of interleukin-8.Cancer Res. 2005 Oct 1;65(19):8784-91. doi: 10.1158/0008-5472.CAN-04-4422.
1055 Hepatitis B virus protein up-regulated HLJ1 expression via the transcription factor YY1 in human hepatocarcinoma cells.Virus Res. 2011 Apr;157(1):76-81. doi: 10.1016/j.virusres.2011.02.009. Epub 2011 Feb 21.
1056 BET protein bromodomain inhibitor-based combinations are highly active against post-myeloproliferative neoplasm secondary AML cells.Leukemia. 2017 Mar;31(3):678-687. doi: 10.1038/leu.2016.260. Epub 2016 Sep 28.
1057 Withaferin A inhibits matrix metalloproteinase-9 activity by suppressing the Akt signaling pathway.Oncol Rep. 2013 Aug;30(2):933-8. doi: 10.3892/or.2013.2487. Epub 2013 May 23.
1058 Suppression of Prostate Cancer Metastasis by DPYSL3-Targeted saRNA.Adv Exp Med Biol. 2017;983:207-216. doi: 10.1007/978-981-10-4310-9_15.
1059 DRAM2 acts as an oncogene in non-small cell lung cancer and suppresses the expression of p53.J Exp Clin Cancer Res. 2019 Feb 12;38(1):72. doi: 10.1186/s13046-019-1068-4.
1060 The tumor metastasis suppressor gene Drg-1 down-regulates the expression of activating transcription factor 3 in prostate cancer.Cancer Res. 2006 Dec 15;66(24):11983-90. doi: 10.1158/0008-5472.CAN-06-0943.
1061 Desmocollin? affects the adhesive strength and cytoskeletal arrangement in esophageal squamous cell carcinoma cells.Mol Med Rep. 2014 Nov;10(5):2358-64. doi: 10.3892/mmr.2014.2485. Epub 2014 Aug 12.
1062 Altered desmoplakin expression at transcriptional and protein levels provides prognostic information in human oropharyngeal cancer.Hum Pathol. 2009 Sep;40(9):1320-9. doi: 10.1016/j.humpath.2009.02.002. Epub 2009 Apr 22.
1063 Association of dipeptidyl peptidase 4 inhibitors with risk of metastases in patients with type 2 diabetes and breast, prostate or digestive system cancer.J Diabetes Complications. 2017 Apr;31(4):687-692. doi: 10.1016/j.jdiacomp.2017.01.012. Epub 2017 Jan 26.
1064 EFS shows biallelic methylation in uveal melanoma with poor prognosis as well as tissue-specific methylation.BMC Cancer. 2011 Aug 26;11:380. doi: 10.1186/1471-2407-11-380.
1065 Prognostic significance of miR-34a in Ewing sarcoma is associated with cyclin D1 and ki-67 expression.Ann Oncol. 2014 Oct;25(10):2080-2086. doi: 10.1093/annonc/mdu249. Epub 2014 Jul 10.
1066 Genetic Profiling of Primary Orbital Melanoma: An Analysis of 6 Cases with Clinicopathologic Correlation.Ophthalmology. 2019 Jul;126(7):1045-1052. doi: 10.1016/j.ophtha.2018.12.047. Epub 2018 Dec 31.
1067 Expression of the p185 encoded by HER2 oncogene in normal and transformed human tissues.Int J Cancer. 1990 Mar 15;45(3):457-61. doi: 10.1002/ijc.2910450314.
1068 Amplification of EIF3S3 gene is associated with advanced stage in prostate cancer.Am J Pathol. 2001 Dec;159(6):2089-94. doi: 10.1016/S0002-9440(10)63060-X.
1069 Cancer Targeted Gene Therapy for Inhibition of Melanoma Lung Metastasis with eIF3i shRNA Loaded Liposomes.Mol Pharm. 2020 Jan 6;17(1):229-238. doi: 10.1021/acs.molpharmaceut.9b00943. Epub 2019 Dec 10.
1070 eIF4F is a nexus of resistance to anti-BRAF and anti-MEK cancer therapies.Nature. 2014 Sep 4;513(7516):105-9. doi: 10.1038/nature13572. Epub 2014 Jul 27.
1071 DAL-1 attenuates epithelial-to mesenchymal transition in lung cancer.J Exp Clin Cancer Res. 2015 Jan 22;34(1):3. doi: 10.1186/s13046-014-0117-2.
1072 Circulating tumor cell-related transcripts in blood as prognostic biomarkers of early recurrence after liver resection for colorectal metastases.Int J Biol Markers. 2019 Sep;34(3):269-275. doi: 10.1177/1724600819849438. Epub 2019 Jun 18.
1073 Loss of heterozygosity and lack of mutations of the XPG/ERCC5 DNA repair gene at 13q33 in prostate cancer.Prostate. 1999 Nov 1;41(3):190-5. doi: 10.1002/(sici)1097-0045(19991101)41:3<190::aid-pros6>3.0.co;2-2.
1074 Role of endothelial cell-selective adhesion molecule in hematogeneous metastasis.Microvasc Res. 2010 Jul;80(1):133-41. doi: 10.1016/j.mvr.2010.02.006. Epub 2010 Feb 11.
1075 ESCO2 inhibits tumor metastasis via transcriptionally repressing MMP2 in colorectal cancer.Cancer Manag Res. 2018 Nov 22;10:6157-6166. doi: 10.2147/CMAR.S181265. eCollection 2018.
1076 siRNAs target sites selection of ezrin and the influence of RNA interference on ezrin expression and biological characters of osteosarcoma cells.Mol Cell Biochem. 2012 May;364(1-2):363-71. doi: 10.1007/s11010-012-1238-6.
1077 Primary cutaneous and subcutaneous Ewing sarcoma.Pediatr Blood Cancer. 2015 Sep;62(9):1555-61. doi: 10.1002/pbc.25535. Epub 2015 Apr 20.
1078 Exo70 isoform switching upon epithelial-mesenchymal transition mediates cancer cell invasion.Dev Cell. 2013 Dec 9;27(5):560-73. doi: 10.1016/j.devcel.2013.10.020.
1079 The fatty acid binding protein 7 (FABP7) is involved in proliferation and invasion of melanoma cells.BMC Cancer. 2008 Sep 30;8:276. doi: 10.1186/1471-2407-8-276.
1080 LFG-500 inhibits the invasion of cancer cells via down-regulation of PI3K/AKT/NF-B signaling pathway.PLoS One. 2014 Mar 11;9(3):e91332. doi: 10.1371/journal.pone.0091332. eCollection 2014.
1081 Loss of the novel mitochondrial protein FAM210B promotes metastasis via PDK4-dependent metabolic reprogramming.Cell Death Dis. 2017 Jun 8;8(6):e2870. doi: 10.1038/cddis.2017.273.
1082 Patterns of somatic alterations between matched primary and metastatic colorectal tumors characterized by whole-genome sequencing.Genomics. 2014 Oct;104(4):234-41. doi: 10.1016/j.ygeno.2014.07.012. Epub 2014 Jul 25.
1083 Human breast-cancer metastasis formation in a nude-mouse model: studies of hyaluronidase, hyaluronan and hyaluronan-binding sites in metastatic cells.Int J Cancer. 1999 Jul 2;82(1):77-83. doi: 10.1002/(sici)1097-0215(19990702)82:1<77::aid-ijc14>3.0.co;2-q.
1084 Oncogenic fibulin-5 promotes nasopharyngeal carcinoma cell metastasis through the FLJ10540/AKT pathway and correlates with poor prognosis.PLoS One. 2013 Dec 27;8(12):e84218. doi: 10.1371/journal.pone.0084218. eCollection 2013.
1085 Fibroblast growth factor 17 is over-expressed in human prostate cancer.J Pathol. 2004 Dec;204(5):578-86. doi: 10.1002/path.1668.
1086 Up-regulation of fibroblast growth factor 3 is associated with tumor metastasis and recurrence in human hepatocellular carcinoma.Cancer Lett. 2007 Jul 8;252(1):36-42. doi: 10.1016/j.canlet.2006.12.003. Epub 2007 Jan 9.
1087 Overexpression of FMNL2 is closely related to metastasis of colorectal cancer.Int J Colorectal Dis. 2008 Nov;23(11):1041-7. doi: 10.1007/s00384-008-0520-2. Epub 2008 Jul 30.
1088 Toca-1 is suppressed by p53 to limit breast cancer cell invasion and tumor metastasis.Breast Cancer Res. 2014 Dec 30;16(6):3413. doi: 10.1186/s13058-014-0503-x.
1089 Up-regulated microRNA-143 transcribed by nuclear factor kappa B enhances hepatocarcinoma metastasis by repressing fibronectin expression.Hepatology. 2009 Aug;50(2):490-9. doi: 10.1002/hep.23008.
1090 FOXA2 functions as a suppressor of tumor metastasis by inhibition of epithelial-to-mesenchymal transition in human lung cancers.Cell Res. 2011 Feb;21(2):316-26. doi: 10.1038/cr.2010.126. Epub 2010 Sep 7.
1091 Differential expression of invasion promoting genes in childhood rhabdomyosarcoma.Int J Oncol. 2011 Apr;38(4):993-1000. doi: 10.3892/ijo.2011.921. Epub 2011 Jan 24.
1092 Forkhead box (FOX) G1 promotes hepatocellular carcinoma epithelial-Mesenchymal transition by activating Wnt signal through forming T-cell factor-4/Beta-catenin/FOXG1 complex.J Exp Clin Cancer Res. 2019 Nov 27;38(1):475. doi: 10.1186/s13046-019-1433-3.
1093 Knockdown of FOXO3a induces epithelial-mesenchymal transition and promotes metastasis of pancreatic ductal adenocarcinoma by activation of the -catenin/TCF4 pathway through SPRY2.J Exp Clin Cancer Res. 2019 Jan 28;38(1):38. doi: 10.1186/s13046-019-1046-x.
1094 ADAM9 enhances CDCP1 by inhibiting miR-1 through EGFR signaling activation in lung cancer metastasis.Oncotarget. 2017 Jul 18;8(29):47365-47378. doi: 10.18632/oncotarget.17648.
1095 Over-expression of FSIP1 promotes breast cancer progression and confers resistance to docetaxel via MRP1 stabilization.Cell Death Dis. 2019 Feb 27;10(3):204. doi: 10.1038/s41419-018-1248-8.
1096 Reduced expression of -L-Fucosidase-1 (FUCA-1) predicts recurrence and shorter cancer specific survival in luminal B LN+ breast cancer patients.Oncotarget. 2018 Feb 7;9(20):15228-15238. doi: 10.18632/oncotarget.24445. eCollection 2018 Mar 16.
1097 MicroRNA-375 suppresses human colorectal cancer metastasis by targeting Frizzled 8.Oncotarget. 2016 Jun 28;7(26):40644-40656. doi: 10.18632/oncotarget.9811.
1098 miR-196b-5p Regulates Colorectal Cancer Cell Migration and Metastases through Interaction with HOXB7 and GALNT5.Clin Cancer Res. 2017 Sep 1;23(17):5255-5266. doi: 10.1158/1078-0432.CCR-17-0023. Epub 2017 May 22.
1099 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1.Nat Cell Biol. 2008 May;10(5):593-601. doi: 10.1038/ncb1722. Epub 2008 Mar 30.
1100 Heterotrimeric G-protein alpha-12 (G12) subunit promotes oral cancer metastasis.Oncotarget. 2014 Oct 30;5(20):9626-40. doi: 10.18632/oncotarget.2437.
1101 A polymorphism in the G protein beta3-subunit gene is associated with bone metastasis risk in breast cancer patients.Breast Cancer Res Treat. 2008 Oct;111(3):449-52. doi: 10.1007/s10549-007-9808-0. Epub 2007 Nov 4.
1102 Cleaved caspase-3 and nuclear factor-kappaB p65 are prognostic factors in metastatic serous ovarian carcinoma.Hum Pathol. 2009 Jun;40(6):795-806. doi: 10.1016/j.humpath.2008.10.019. Epub 2009 Jan 20.
1103 Metastasis-associated gene, mag-1 improves tumour microenvironmental adaptation and potentiates tumour metastasis.J Cell Mol Med. 2012 Dec;16(12):3037-51. doi: 10.1111/j.1582-4934.2012.01633.x.
1104 Glypican 6 is a putative biomarker for metastatic progression of cutaneous melanoma.PLoS One. 2019 Jun 14;14(6):e0218067. doi: 10.1371/journal.pone.0218067. eCollection 2019.
1105 Ovarian cancer G protein-coupled receptor 1, a new metastasis suppressor gene in prostate cancer.J Natl Cancer Inst. 2007 Sep 5;99(17):1313-27. doi: 10.1093/jnci/djm107. Epub 2007 Aug 28.
1106 A novel variant of human Grb7 is associated with invasive esophageal carcinoma.J Clin Invest. 1998 Aug 15;102(4):821-7. doi: 10.1172/JCI2921.
1107 Aberrant activation of androgen receptor in a new neuropeptide-autocrine model of androgen-insensitive prostate cancer.Cancer Res. 2009 Jan 1;69(1):151-60. doi: 10.1158/0008-5472.CAN-08-0442.
1108 Technetium-99m-pertechnetate whole-body SPET/CT scan in thyroidectomized differentiated thyroid cancer patients is a useful imaging modality in detecting remnant thyroid tissue, nodal and distant metastases before (131)I therapy. A study of 416 patients.Hell J Nucl Med. 2018 May-Aug;21(2):121-124.
1109 Up-regulation of GTPBP4 in colorectal carcinoma is responsible for tumor metastasis.Biochem Biophys Res Commun. 2016 Nov 4;480(1):48-54. doi: 10.1016/j.bbrc.2016.10.010. Epub 2016 Oct 5.
1110 Hyaluronan synthase and hyaluronidase expression in serous ovarian carcinoma is related to anatomic site and chemotherapy exposure.Int J Mol Sci. 2012 Oct 10;13(10):12925-38. doi: 10.3390/ijms131012925.
1111 Evolution of the androgen receptor pathway during progression of prostate cancer.Cancer Res. 2006 May 15;66(10):5012-20. doi: 10.1158/0008-5472.CAN-05-3082.
1112 Detection of differentially expressed HES-6 gene in metastatic colon carcinoma by combination of suppression subtractive hybridization and cDNA library array.Cancer Lett. 2003 Aug 20;198(2):229-39. doi: 10.1016/s0304-3835(03)00313-6.
1113 The notch target gene HEYL modulates metastasis forming capacity of colorectal cancer patient-derived spheroid cells in vivo.BMC Cancer. 2019 Dec 3;19(1):1181. doi: 10.1186/s12885-019-6396-4.
1114 WITHDRAWN: Upregulation of HINT2 Inhibits Non-Small Cell Lung Cancer Cell Invasion Via COX-2/PGE?Mediated Activation of -catenin Signaling.Oncol Res. 2017 Aug 11. doi: 10.3727/096504017X15021536183508. Online ahead of print.
1115 Huntingtin-Interacting Protein-1 Is an Early-Stage Prognostic Biomarker of Lung Adenocarcinoma and Suppresses Metastasis via Akt-mediated Epithelial-Mesenchymal Transition.Am J Respir Crit Care Med. 2016 Apr 15;193(8):869-80. doi: 10.1164/rccm.201412-2226OC.
1116 T-cell Responses to TP53 "Hotspot" Mutations and Unique Neoantigens Expressed by Human Ovarian Cancers.Clin Cancer Res. 2018 Nov 15;24(22):5562-5573. doi: 10.1158/1078-0432.CCR-18-0573. Epub 2018 May 31.
1117 Extracellular Matrix Receptor Expression in Subtypes of Lung Adenocarcinoma Potentiates Outgrowth of Micrometastases.Cancer Res. 2017 Apr 15;77(8):1905-1917. doi: 10.1158/0008-5472.CAN-16-1978. Epub 2017 Feb 14.
1118 Heterogeneous nuclear ribonucleoprotein K (hnRNP-K) promotes tumor metastasis by induction of genes involved in extracellular matrix, cell movement, and angiogenesis.J Biol Chem. 2013 May 24;288(21):15046-56. doi: 10.1074/jbc.M113.466136. Epub 2013 Apr 5.
1119 Potential role of the HOXD8 transcription factor in cisplatin resistance and tumour metastasis in advanced epithelial ovarian cancer.Sci Rep. 2018 Sep 7;8(1):13483. doi: 10.1038/s41598-018-31030-3.
1120 Heparanase 2 interacts with heparan sulfate with high affinity and inhibits heparanase activity.J Biol Chem. 2010 Sep 3;285(36):28010-9. doi: 10.1074/jbc.M110.116384. Epub 2010 Jun 24.
1121 Antagonism between HTRA3 and TGF1 Contributes to Metastasis in Non-Small Cell Lung Cancer.Cancer Res. 2019 Jun 1;79(11):2853-2864. doi: 10.1158/0008-5472.CAN-18-2507. Epub 2019 Apr 2.
1122 HUNK suppresses metastasis of basal type breast cancers by disrupting the interaction between PP2A and cofilin-1.Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2622-7. doi: 10.1073/pnas.0914492107. Epub 2010 Jan 22.
1123 Sustained delivery and efficacy of polymeric nanoparticles containing osteopontin and bone sialoprotein antisenses in rats with breast cancer bone metastasis.Int J Cancer. 2010 Apr 1;126(7):1749-60. doi: 10.1002/ijc.24890.
1124 VICKZ1 enhances tumor progression and metastasis in lung adenocarcinomas in mice.Oncogene. 2019 May;38(21):4169-4181. doi: 10.1038/s41388-019-0715-8. Epub 2019 Jan 30.
1125 High metastatic efficiency of human sarcoma cells in Rag2/gammac double knockout mice provides a powerful test system for antimetastatic targeted therapy.Eur J Cancer. 2010 Feb;46(3):659-68. doi: 10.1016/j.ejca.2009.11.018. Epub 2009 Dec 22.
1126 -Internexin: a novel biomarker for pancreatic neuroendocrine tumor aggressiveness.J Clin Endocrinol Metab. 2014 May;99(5):E786-95. doi: 10.1210/jc.2013-2874. Epub 2014 Jan 31.
1127 Engagement of overexpressed Her2 with GEP100 induces autonomous invasive activities and provides a biomarker for metastases of lung adenocarcinoma.PLoS One. 2011;6(9):e25301. doi: 10.1371/journal.pone.0025301. Epub 2011 Sep 22.
1128 Engagement of IIb3 (GPIIb/IIIa) with 3 integrin mediates interaction of melanoma cells with platelets: a connection to hematogenous metastasis.J Biol Chem. 2012 Jan 13;287(3):2168-78. doi: 10.1074/jbc.M111.269811. Epub 2011 Nov 18.
1129 Altered integrin expression patterns shown by microarray in human cutaneous melanoma.Melanoma Res. 2017 Jun;27(3):180-188. doi: 10.1097/CMR.0000000000000322.
1130 Integrin 4-Targeted Cancer Immunotherapies Inhibit Tumor Growth and Decrease Metastasis.Cancer Res. 2020 Feb 15;80(4):771-783. doi: 10.1158/0008-5472.CAN-19-1145. Epub 2019 Dec 16.
1131 ITIH5 induces a shift in TGF- superfamily signaling involving Endoglin and reduces risk for breast cancer metastasis and tumor death.Mol Carcinog. 2018 Feb;57(2):167-181. doi: 10.1002/mc.22742. Epub 2017 Oct 30.
1132 JARID2 is a direct target of the PAX3-FOXO1 fusion protein and inhibits myogenic differentiation of rhabdomyosarcoma cells.Oncogene. 2014 Feb 27;33(9):1148-57. doi: 10.1038/onc.2013.46. Epub 2013 Feb 25.
1133 Downregulation of AP-1 repressor JDP2 is associated with tumor metastasis and poor prognosis in patients with pancreatic carcinoma.Int J Biol Markers. 2010 Jul-Sep;25(3):136-40. doi: 10.1177/172460081002500303.
1134 Genetic background of different cancer cell lines influences the gene set involved in chromosome 8 mediated breast tumor suppression.Genes Chromosomes Cancer. 2006 Jun;45(6):612-27. doi: 10.1002/gcc.20325.
1135 KDM2B promotes pancreatic cancer via Polycomb-dependent and -independent transcriptional programs.J Clin Invest. 2013 Feb;123(2):727-39. doi: 10.1172/JCI64535. Epub 2013 Jan 16.
1136 Histone Demethylase JMJD2D Interacts With -Catenin to Induce Transcription and Activate Colorectal Cancer Cell Proliferation and Tumor Growth in Mice.Gastroenterology. 2019 Mar;156(4):1112-1126. doi: 10.1053/j.gastro.2018.11.036. Epub 2018 Nov 23.
1137 Ganciclovir prodrug therapy is effective in a murine xenotransplant model of human lung cancer.Ann Thorac Surg. 2002 Mar;73(3):905-10. doi: 10.1016/s0003-4975(01)03413-0.
1138 KIFCI, a novel putative prognostic biomarker for ovarian adenocarcinomas: delineating protein interaction networks and signaling circuitries.J Ovarian Res. 2014 May 12;7:53. doi: 10.1186/1757-2215-7-53. eCollection 2014.
1139 Genome-wide methylation screen in low-grade breast cancer identifies novel epigenetically altered genes as potential biomarkers for tumor diagnosis.FASEB J. 2012 Dec;26(12):4937-50. doi: 10.1096/fj.12-209502. Epub 2012 Aug 28.
1140 KLF9-dependent ROS regulate melanoma progression in stage-specific manner.Oncogene. 2019 May;38(19):3585-3597. doi: 10.1038/s41388-019-0689-6. Epub 2019 Jan 21.
1141 Keratin 13 expression reprograms bone and brain metastases of human prostate cancer cells.Oncotarget. 2016 Dec 20;7(51):84645-84657. doi: 10.18632/oncotarget.13175.
1142 Micrometastases in sentinel nodes of gastric cancer.Br J Cancer. 2003 Aug 18;89(4):676-80. doi: 10.1038/sj.bjc.6601183.
1143 YdjC chitooligosaccharide deacetylase homolog induces keratin reorganization in lung cancer cells: involvement of interaction between YDJC and CDC16.Oncotarget. 2018 May 1;9(33):22915-22928. doi: 10.18632/oncotarget.25145. eCollection 2018 May 1.
1144 Upregulation of miR-374a promotes tumor metastasis and progression by downregulating LACTB and predicts unfavorable prognosis in breast cancer.Cancer Med. 2018 Jul;7(7):3351-3362. doi: 10.1002/cam4.1576. Epub 2018 May 23.
1145 Rapid detection of metastasis of gastric cancer using reverse transcription loop-mediated isothermal amplification.Int J Cancer. 2007 Mar 1;120(5):1063-9. doi: 10.1002/ijc.22397.
1146 (18)F-Branched-Chain Amino Acids: Structure-Activity Relationships and PET Imaging Potential.J Nucl Med. 2019 Jul;60(7):1003-1009. doi: 10.2967/jnumed.118.220483. Epub 2019 Jan 25.
1147 Lactate dehydrogenase-B is silenced by promoter hypermethylation in human prostate cancer.Oncogene. 2006 May 11;25(20):2953-60. doi: 10.1038/sj.onc.1209262.
1148 Galectin-3 Binding Protein Secreted by Breast Cancer Cells Inhibits Monocyte-Derived Fibrocyte Differentiation.J Immunol. 2015 Aug 15;195(4):1858-67. doi: 10.4049/jimmunol.1500365. Epub 2015 Jul 1.
1149 Downregulation of LGI1 promotes tumor metastasis in esophageal squamous cell carcinoma.Carcinogenesis. 2014 May;35(5):1154-61. doi: 10.1093/carcin/bgu040. Epub 2014 Feb 7.
1150 Epidermal growth factor promotes protein degradation of epithelial protein lost in neoplasm (EPLIN), a putative metastasis suppressor, during epithelial-mesenchymal transition.J Biol Chem. 2013 Jan 18;288(3):1469-79. doi: 10.1074/jbc.M112.438341. Epub 2012 Nov 27.
1151 Somatic LMCD1 mutations promoted cell migration and tumor metastasis in hepatocellular carcinoma.Oncogene. 2012 May 24;31(21):2640-52. doi: 10.1038/onc.2011.440. Epub 2011 Sep 26.
1152 A critical role for I kappaB kinase alpha in the development of human and mouse squamous cell carcinomas.Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17202-7. doi: 10.1073/pnas.0604481103. Epub 2006 Nov 1.
1153 Exosome-mediated secretion of LOXL4 promotes hepatocellular carcinoma cell invasion and metastasis.Mol Cancer. 2019 Jan 31;18(1):18. doi: 10.1186/s12943-019-0948-8.
1154 Validation of RNA arbitrarily primed PCR probes hybridized to glass cDNA microarrays: application to the analysis of limited samples.Clin Chem. 2005 Jan;51(1):93-101. doi: 10.1373/clinchem.2004.036236.
1155 ORAOV1 is a probable target within the 11q13.3 amplicon in lymph node metastases from gastric adenocarcinoma.Int J Mol Med. 2012 Jan;29(1):81-7. doi: 10.3892/ijmm.2011.811. Epub 2011 Oct 11.
1156 Tumor-suppressive functions of leucine zipper transcription factor-like 1.Cancer Res. 2010 Apr 1;70(7):2942-50. doi: 10.1158/0008-5472.CAN-09-3826. Epub 2010 Mar 16.
1157 Predicting neuroendocrine tumor (carcinoid) neoplasia using gene expression profiling and supervised machine learning.Cancer. 2009 Apr 15;115(8):1638-50. doi: 10.1002/cncr.24180.
1158 MAL2 expression predicts distant metastasis and short survival in pancreatic cancer.Surgery. 2013 Sep;154(3):573-82. doi: 10.1016/j.surg.2013.03.010. Epub 2013 Jul 19.
1159 Differentiation of classic medulloblastoma into metastatic large cell medulloblastoma with focal rhabdoid differentiation in the absence of posterior fossa recurrence.Acta Neuropathol. 2005 May;109(5):543-51. doi: 10.1007/s00401-005-0986-8. Epub 2005 Mar 10.
1160 The prognostic value of MARCKS-like 1 in lymph node-negative breast cancer.Breast Cancer Res Treat. 2012 Sep;135(2):381-90. doi: 10.1007/s10549-012-2155-9. Epub 2012 Jul 8.
1161 Methyl-CpG Binding Domain Protein 2 Inhibits the Malignant Characteristic of Lung Adenocarcinoma through the Epigenetic Modulation of 10 to 11 Translocation 1 and miR-200s.Am J Pathol. 2019 May;189(5):1065-1076. doi: 10.1016/j.ajpath.2019.01.010. Epub 2019 Feb 5.
1162 MCRS1 overexpression, which is specifically inhibited by miR-129*, promotes the epithelial-mesenchymal transition and metastasis in non-small cell lung cancer.Mol Cancer. 2014 Nov 6;13:245. doi: 10.1186/1476-4598-13-245.
1163 MDC1 promotes ovarian cancer metastasis by inducing epithelial-mesenchymal transition.Tumour Biol. 2015 Jun;36(6):4261-9. doi: 10.1007/s13277-015-3063-5. Epub 2015 Jan 16.
1164 Mediator of RNA polymerase II transcription subunit 19 promotes osteosarcoma growth and metastasis and associates with prognosis.Eur J Cancer. 2014 Apr;50(6):1125-36. doi: 10.1016/j.ejca.2014.01.030. Epub 2014 Feb 21.
1165 Transcriptional regulation of KiSS-1 gene expression in metastatic melanoma by specificity protein-1 and its coactivator DRIP-130.Oncogene. 2007 Mar 15;26(12):1739-47. doi: 10.1038/sj.onc.1209963. Epub 2006 Sep 11.
1166 Upregulated METTL3 promotes metastasis of colorectal Cancer via miR-1246/SPRED2/MAPK signaling pathway.J Exp Clin Cancer Res. 2019 Sep 6;38(1):393. doi: 10.1186/s13046-019-1408-4.
1167 Modulation of CD147-induced matrix metalloproteinase activity: role of CD147 N-glycosylation.Biochem J. 2013 Jan 15;449(2):437-48. doi: 10.1042/BJ20120343.
1168 Overexpression of matrix Gla protein mRNA in malignant human breast cells: isolation by differential cDNA hybridization.Oncogene. 1990 Sep;5(9):1391-5.
1169 Expression of vascular endothelial growth factor and proliferation marker MIB1 are influenced by neoadjuvant chemotherapy in locally advanced breast cancer.Appl Immunohistochem Mol Morphol. 2005 Jun;13(2):147-56. doi: 10.1097/01.pai.0000137364.36091.b0.
1170 Macrophage inflammatory protein-3alpha is a novel serum marker for nasopharyngeal carcinoma detection and prediction of treatment outcomes.Clin Cancer Res. 2008 Nov 1;14(21):6979-87. doi: 10.1158/1078-0432.CCR-08-0090.
1171 AF1q Expression Associates with CD44 and STAT3 and Impairs Overall Survival in Adenoid Cystic Carcinoma of the Head and Neck.Pathol Oncol Res. 2020 Apr;26(2):1287-1292. doi: 10.1007/s12253-019-00696-z. Epub 2019 Jul 4.
1172 MMP28 (epilysin) as a novel promoter of invasion and metastasis in gastric cancer.BMC Cancer. 2011 May 26;11:200. doi: 10.1186/1471-2407-11-200.
1173 Expression of stromal cell markers in distinct compartments of human skin cancers.J Cutan Pathol. 2006 Feb;33(2):145-55. doi: 10.1111/j.0303-6987.2006.00446.x.
1174 Identification of URIM, a novel gene up-regulated in metastasis.Anticancer Res. 1999 Jan-Feb;19(1A):525-30.
1175 Loss of MSH3 protein expression is frequent in MLH1-deficient colorectal cancer and is associated with disease progression.Cancer Res. 2004 Feb 1;64(3):864-70. doi: 10.1158/0008-5472.can-03-2807.
1176 Metallothionein 1E is methylated in malignant melanoma and increases sensitivity to cisplatin-induced apoptosis.Melanoma Res. 2010 Oct;20(5):392-400.
1177 Metallothionein 1 h tumour suppressor activity in prostate cancer is mediated by euchromatin methyltransferase 1.J Pathol. 2013 Jun;230(2):184-93. doi: 10.1002/path.4169.
1178 Downregulation of metastasis suppressor 1(MTSS1) is associated with nodal metastasis and poor outcome in Chinese patients with gastric cancer.BMC Cancer. 2010 Aug 15;10:428. doi: 10.1186/1471-2407-10-428.
1179 Prognostic relevance of occult metastases detected by cytokeratin 20 and mucin 2 mRNA levels in sentinel lymph nodes from colon cancer patients.Ann Surg Oncol. 2012 Nov;19(12):3719-26. doi: 10.1245/s10434-012-2454-8. Epub 2012 Jul 3.
1180 B-myb is a gene implicated in cell cycle and proliferation of breast cancer.Int J Clin Exp Pathol. 2014 Aug 15;7(9):5819-27. eCollection 2014.
1181 Gene amplification and gene dosage in cell lines derived from squamous cell carcinoma of the head and neck.Genes Chromosomes Cancer. 1991 Nov;3(6):443-54. doi: 10.1002/gcc.2870030606.
1182 MicroRNA let-7f inhibits tumor invasion and metastasis by targeting MYH9 in human gastric cancer.PLoS One. 2011 Apr 18;6(4):e18409. doi: 10.1371/journal.pone.0018409.
1183 Selective expression of myosin IC Isoform A in mouse and human cell lines and mouse prostate cancer tissues.PLoS One. 2014 Sep 26;9(9):e108609. doi: 10.1371/journal.pone.0108609. eCollection 2014.
1184 Systemic therapy of experimental breast cancer metastases by mutant vesicular stomatitis virus in immune-competent mice.Cancer Gene Ther. 2005 Apr;12(4):350-8. doi: 10.1038/sj.cgt.7700794.
1185 NANOG modulates stemness in human colorectal cancer.Oncogene. 2013 Sep 12;32(37):4397-405. doi: 10.1038/onc.2012.461. Epub 2012 Oct 22.
1186 Regulation of metastasis; mitochondrial DNA mutations have appeared on stage.J Bioenerg Biomembr. 2012 Dec;44(6):639-44. doi: 10.1007/s10863-012-9468-6.
1187 N-myc downstream-regulated gene 1 inhibits the proliferation of colorectal cancer through emulative antagonizing NEDD4-mediated ubiquitylation of p21.J Exp Clin Cancer Res. 2019 Dec 12;38(1):490. doi: 10.1186/s13046-019-1476-5.
1188 Low expression of N-myc downstream-regulated gene 2 (NDRG2) correlates with poor prognosis in hepatoblastoma.Hepatol Int. 2016 Mar;10(2):370-6. doi: 10.1007/s12072-015-9686-1. Epub 2015 Dec 8.
1189 Eutopic endometrium and peritoneal, ovarian and colorectal endometriotic tissues express a different profile of nectin-1, -3, -4 and nectin-like molecule 2.Hum Reprod. 2012 Nov;27(11):3179-86. doi: 10.1093/humrep/des304. Epub 2012 Aug 27.
1190 Decreased expression of NEDD4L contributes to NSCLC progression and metastasis.Biochem Biophys Res Commun. 2019 May 28;513(2):398-404. doi: 10.1016/j.bbrc.2019.04.001. Epub 2019 Apr 6.
1191 Characterization of paired tumor and non-tumor cell lines established from patients with breast cancer.Int J Cancer. 1998 Dec 9;78(6):766-74. doi: 10.1002/(sici)1097-0215(19981209)78:6<766::aid-ijc15>3.0.co;2-l.
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1193 NFAT3 transcription factor inhibits breast cancer cell motility by targeting the Lipocalin 2 gene.Oncogene. 2010 Apr 15;29(15):2292-301. doi: 10.1038/onc.2009.499. Epub 2010 Jan 25.
1194 Exploring the spatiotemporal genetic heterogeneity in metastatic lung adenocarcinoma using a nuclei flow-sorting approach.J Pathol. 2019 Feb;247(2):199-213. doi: 10.1002/path.5183. Epub 2018 Dec 28.
1195 Novel markers of subclinical disease for Ewing family tumors from gene expression profiling.Clin Cancer Res. 2007 Dec 1;13(23):6978-83. doi: 10.1158/1078-0432.CCR-07-1417.
1196 Targeted design and identification of AC1NOD4Q to block activity of HOTAIR by abrogating the scaffold interaction with EZH2.Clin Epigenetics. 2019 Feb 14;11(1):29. doi: 10.1186/s13148-019-0624-2.
1197 Combination of laser microdissection, 2D-DIGE and MALDI-TOF MS to identify protein biomarkers to predict colorectal cancer spread.Clin Proteomics. 2019 Jan 22;16:3. doi: 10.1186/s12014-019-9223-7. eCollection 2019.
1198 Suppression of miRNA-708 by polycomb group promotes metastases by calcium-induced cell migration.Cancer Cell. 2013 Jan 14;23(1):63-76. doi: 10.1016/j.ccr.2012.11.019.
1199 Highly bright and stable NIR-BRET with blue-shifted coelenterazine derivatives for deep-tissue imaging of molecular events in vivo.Theranostics. 2019 Apr 13;9(9):2646-2661. doi: 10.7150/thno.32219. eCollection 2019.
1200 Loss of expression of a 55 kDa nuclear protein (nmt55) in estrogen receptor-negative human breast cancer.Diagn Mol Pathol. 1997 Aug;6(4):209-21. doi: 10.1097/00019606-199708000-00005.
1201 Differential baseline and response profile to IFN-gamma gene transduction of IL-6/IL-6 receptor-alpha secretion discriminate primary tumors versus bone marrow metastases of nasopharyngeal carcinomas in culture.BMC Cancer. 2009 Jun 5;9:169. doi: 10.1186/1471-2407-9-169.
1202 NSD2 inhibition suppresses metastasis in cervical cancer by promoting TGF-/TGF-RI/SMADs signaling.Biochem Biophys Res Commun. 2019 Nov 12;519(3):489-496. doi: 10.1016/j.bbrc.2019.08.020. Epub 2019 Sep 14.
1203 NTN4 is associated with breast cancer metastasis via regulation of EMT-related biomarkers.Oncol Rep. 2017 Jan;37(1):449-457. doi: 10.3892/or.2016.5239. Epub 2016 Nov 9.
1204 NUBPL, a novel metastasis-related gene, promotes colorectal carcinoma cell motility by inducing epithelial-mesenchymal transition.Cancer Sci. 2017 Jun;108(6):1169-1176. doi: 10.1111/cas.13243. Epub 2017 Jun 14.
1205 Different expression of occludin and ZO-1 in primary and metastatic liver tumors.Pathol Oncol Res. 2008 Sep;14(3):299-306. doi: 10.1007/s12253-008-9031-2. Epub 2008 Apr 2.
1206 OLIG2 as a specific marker of oligodendroglial tumour cells.Lancet. 2001 Jul 28;358(9278):298-300. doi: 10.1016/S0140-6736(01)05499-X.
1207 HNF6 promotes tumor growth in colorectal cancer and enhances liver metastasis in mouse model.J Cell Physiol. 2019 Apr;234(4):3675-3684. doi: 10.1002/jcp.27140. Epub 2018 Sep 7.
1208 Inhibition of hepatocarcinoma and tumor metastasis to liver by gene therapy with recombinant CBD-HepII polypeptide of fibronectin.Int J Cancer. 2007 Jul 1;121(1):184-92. doi: 10.1002/ijc.22644.
1209 Olfactory receptor 51E1 protein as a potential novel tissue biomarker for small intestine neuroendocrine carcinomas.Eur J Endocrinol. 2013 Jan 17;168(2):253-61. doi: 10.1530/EJE-12-0814. Print 2013 Feb.
1210 Expression of oxysterol binding protein isoforms in opisthorchiasis-associated cholangiocarcinoma: a potential molecular marker for tumor metastasis.Parasitol Int. 2012 Mar;61(1):136-9. doi: 10.1016/j.parint.2011.07.003. Epub 2011 Jul 8.
1211 Investigating the expression, effect and tumorigenic pathway of PADI2 in tumors.Onco Targets Ther. 2017 Mar 8;10:1475-1485. doi: 10.2147/OTT.S92389. eCollection 2017.
1212 Complexation of Chol-DsiRNA in place of Chol-siRNA greatly increases the duration of mRNA suppression by polyplexes of PLL(30)-PEG(5K) in primary murine syngeneic breast tumors after i.v. administration.Int J Pharm. 2018 May 30;543(1-2):130-138. doi: 10.1016/j.ijpharm.2018.03.045. Epub 2018 Mar 27.
1213 Overexpression of PAFAH1B1 is associated with tumor metastasis and poor survival in non-small cell lung cancer.Lung Cancer. 2012 Sep;77(3):585-92. doi: 10.1016/j.lungcan.2012.05.105. Epub 2012 Jun 29.
1214 Loss of pannexin 1 attenuates melanoma progression by reversion to a melanocytic phenotype.J Biol Chem. 2012 Aug 17;287(34):29184-93. doi: 10.1074/jbc.M112.377176. Epub 2012 Jun 29.
1215 Upregulation of PAX2 promotes the metastasis of esophageal cancer through interleukin-5.Cell Physiol Biochem. 2015;35(2):740-54. doi: 10.1159/000369734. Epub 2015 Jan 30.
1216 Unexpected PAX8 Immunoreactivity in Metastatic High-grade Breast Cancer.Appl Immunohistochem Mol Morphol. 2019 Oct;27(9):637-643. doi: 10.1097/PAI.0000000000000707.
1217 MicroRNA-33a-3p suppresses cell migration and invasion by directly targeting PBX3 in human hepatocellular carcinoma.Oncotarget. 2016 Jul 5;7(27):42461-42473. doi: 10.18632/oncotarget.9886.
1218 3'-UTR-mediated post-transcriptional regulation of cancer metastasis: beginning at the end.RNA Biol. 2011 Jul-Aug;8(4):595-9. doi: 10.4161/rna.8.4.16018. Epub 2011 Jul 1.
1219 Analysis of Mel-18 expression in prostate cancer tissues and correlation with clinicopathologic features.Urol Oncol. 2011 May-Jun;29(3):244-51. doi: 10.1016/j.urolonc.2009.02.004. Epub 2009 Apr 22.
1220 PDLIM1 Inhibits Tumor Metastasis Through Activating Hippo Signaling in Hepatocellular Carcinoma.Hepatology. 2020 May;71(5):1643-1659. doi: 10.1002/hep.30930. Epub 2020 Jan 21.
1221 PEA15 promotes liver metastasis of colorectal cancer by upregulating the ERK/MAPK signaling pathway.Oncol Rep. 2019 Jan;41(1):43-56. doi: 10.3892/or.2018.6825. Epub 2018 Oct 25.
1222 Significance of PELP1/HDAC2/miR-200 regulatory network in EMT and metastasis of breast cancer.Oncogene. 2014 Jul 10;33(28):3707-16. doi: 10.1038/onc.2013.332. Epub 2013 Aug 26.
1223 Loss of heterozygosity of gene THW is frequently found in melanoma metastases.Anticancer Res. 2001 Mar-Apr;21(2A):1071-80.
1224 PFKFB4 Promotes Breast Cancer Metastasis via Induction of Hyaluronan Production in a p38-Dependent Manner.Cell Physiol Biochem. 2018;50(6):2108-2123. doi: 10.1159/000495055. Epub 2018 Nov 9.
1225 Loss of profilin2 contributes to enhanced epithelial-mesenchymal transition and metastasis of colorectal cancer.Int J Oncol. 2018 Sep;53(3):1118-1128. doi: 10.3892/ijo.2018.4475. Epub 2018 Jul 9.
1226 PGK1 is a Potential Survival Biomarker and Invasion Promoter by Regulating the HIF-1-Mediated Epithelial-Mesenchymal Transition Process in Breast Cancer.Cell Physiol Biochem. 2018;51(5):2434-2444. doi: 10.1159/000495900. Epub 2018 Dec 11.
1227 The Prognostic Relevance of Sentinel Lymph Node Metastases Assessed by PHGR1 mRNA Quantification in Stage I to III Colon Cancer.Transl Oncol. 2018 Apr;11(2):436-443. doi: 10.1016/j.tranon.2018.01.015. Epub 2018 Feb 21.
1228 PHLDA1 expression marks the putative epithelial stem cells and contributes to intestinal tumorigenesis.Cancer Res. 2011 May 15;71(10):3709-19. doi: 10.1158/0008-5472.CAN-10-2342. Epub 2011 May 10.
1229 The role of polymeric immunoglobulin receptor in inflammation-induced tumor metastasis of human hepatocellular carcinoma.J Natl Cancer Inst. 2011 Nov 16;103(22):1696-712. doi: 10.1093/jnci/djr360. Epub 2011 Oct 24.
1230 Overexpression of PIWI proteins in human stage III epithelial ovarian cancer with lymph node metastasis.Cancer Biomark. 2013;13(5):315-21. doi: 10.3233/CBM-130360.
1231 Genomic aberrations in the HTPAP promoter affect tumor metastasis and clinical prognosis of hepatocellular carcinoma.PLoS One. 2014 Mar 6;9(3):e90528. doi: 10.1371/journal.pone.0090528. eCollection 2014.
1232 ErbB-2 signals through Plexin-B1 to promote breast cancer metastasis.J Clin Invest. 2012 Apr;122(4):1296-305. doi: 10.1172/JCI60568. Epub 2012 Mar 1.
1233 Expression of telomere binding proteins in gastric cancer and correlation with clinicopathological parameters.Asia Pac J Clin Oncol. 2011 Dec;7(4):339-45. doi: 10.1111/j.1743-7563.2011.01437.x.
1234 Visualization of the metastatic process by green fluorescent protein expression.Anticancer Res. 1997 Jul-Aug;17(4A):2377-84.
1235 Expression of a restrictive receptor for interleukin 13 is associated with glial transformation.J Neurooncol. 2000 Jun;48(2):103-11. doi: 10.1023/a:1006446426611.
1236 SOX2 and SOX9 are markers of clinically aggressive disease in metastatic high-grade serous carcinoma.Gynecol Oncol. 2019 Jun;153(3):651-660. doi: 10.1016/j.ygyno.2019.03.099. Epub 2019 Mar 21.
1237 Pyrophosphatase 1 expression is associated with future recurrence and overall survival in Chinese patients with intrahepatic cholangiocarcinoma.Oncol Lett. 2018 May;15(5):8095-8101. doi: 10.3892/ol.2018.8278. Epub 2018 Mar 15.
1238 Expression of the protein phosphatase 1 inhibitor KEPI is downregulated in breast cancer cell lines and tissues and involved in the regulation of the tumor suppressor EGR1 via the MEK-ERK pathway.Biol Chem. 2007 May;388(5):489-95. doi: 10.1515/BC.2007.062.
1239 Low spinophilin expression enhances aggressive biological behavior of breast cancer.Oncotarget. 2015 May 10;6(13):11191-202. doi: 10.18632/oncotarget.3586.
1240 Genetic associations in classical hodgkin lymphoma: a systematic review and insights into susceptibility mechanisms.Cancer Epidemiol Biomarkers Prev. 2014 Dec;23(12):2737-47. doi: 10.1158/1055-9965.EPI-14-0683. Epub 2014 Sep 9.
1241 Anticancer activity of the PR domain of tumor suppressor RIZ1.Int J Med Sci. 2011 Feb 21;8(2):161-7. doi: 10.7150/ijms.8.161.
1242 PROX1 promotes metabolic adaptation and fuels outgrowth of Wnt(high) metastatic colon cancer cells.Cell Rep. 2014 Sep 25;8(6):1957-1973. doi: 10.1016/j.celrep.2014.08.041. Epub 2014 Sep 18.
1243 New genomic structure for prostate cancer specific gene PCA3 within BMCC1: implications for prostate cancer detection and progression.PLoS One. 2009;4(3):e4995. doi: 10.1371/journal.pone.0004995. Epub 2009 Mar 25.
1244 Loss of receptor protein tyrosine phosphatase / (RPTP/) promotes prostate cancer metastasis.J Biol Chem. 2012 Nov 23;287(48):40339-49. doi: 10.1074/jbc.M112.405852. Epub 2012 Oct 11.
1245 Bit1 in anoikis resistance and tumor metastasis.Cancer Lett. 2013 Jun 10;333(2):147-51. doi: 10.1016/j.canlet.2013.01.043. Epub 2013 Jan 31.
1246 Pituitary tumor-transforming gene 1 is expressed in primary ductal breast carcinoma, lymph node infiltration, and distant metastases.Dis Markers. 2013;35(4):267-72. doi: 10.1155/2013/912304.
1247 Pentraxin 3 overexpression accelerated tumor metastasis and indicated poor prognosis in hepatocellular carcinoma via driving epithelial-mesenchymal transition.J Cancer. 2018 Jun 23;9(15):2650-2658. doi: 10.7150/jca.25188. eCollection 2018.
1248 The bispecific anti-CD3anti-CD155 antibody mediates T cell immunotherapy for human prostate cancer.Invest New Drugs. 2019 Oct;37(5):810-817. doi: 10.1007/s10637-018-0683-9. Epub 2018 Oct 29.
1249 Presence of a new conserved domain in CART1, a novel member of the tumor necrosis factor receptor-associated protein family, which is expressed in breast carcinoma.J Biol Chem. 1995 Oct 27;270(43):25715-21. doi: 10.1074/jbc.270.43.25715.
1250 Hypoxia-induced Rab11-family interacting protein4expression promotes migration and invasion of colon cancer and correlates with poor prognosis.Mol Med Rep. 2018 Mar;17(3):3797-3806. doi: 10.3892/mmr.2017.8283. Epub 2017 Dec 15.
1251 Rab17 inhibits the tumourigenic properties of hepatocellular carcinomas via the Erk pathway.Tumour Biol. 2015 Aug;36(8):5815-24. doi: 10.1007/s13277-015-3251-3. Epub 2015 Feb 24.
1252 Inactivation of Rab23 inhibits the invasion and motility of pancreatic duct adenocarcinoma.Genet Mol Res. 2015 Mar 30;14(1):2707-15. doi: 10.4238/2015.March.30.31.
1253 Rab31 promoted hepatocellular carcinoma (HCC) progression via inhibition of cell apoptosis induced by PI3K/AKT/Bcl-2/BAX pathway.Tumour Biol. 2015 Nov;36(11):8661-70. doi: 10.1007/s13277-015-3626-5. Epub 2015 Jun 6.
1254 RAB38 is a potential prognostic factor for tumor recurrence in non-small cell lung cancer.Oncol Lett. 2019 Sep;18(3):2598-2604. doi: 10.3892/ol.2019.10547. Epub 2019 Jun 28.
1255 RABEX-5 plays an oncogenic role in breast cancer by activating MMP-9 pathway.J Exp Clin Cancer Res. 2013 Aug 13;32(1):52. doi: 10.1186/1756-9966-32-52.
1256 Differential modulation by tumor necrosis factor and immune interferon of HLA class-II antigens expressed by melanoma cells.Int J Cancer. 1989 Sep 15;44(3):554-9. doi: 10.1002/ijc.2910440330.
1257 Inhibition of CRM1-mediated nucleocytoplasmic transport: triggering human melanoma cell apoptosis by perturbing multiple cellular pathways.J Invest Dermatol. 2012 Dec;132(12):2780-90. doi: 10.1038/jid.2012.233. Epub 2012 Jul 26.
1258 Interaction of the Ras-related protein associated with diabetes rad and the putative tumor metastasis suppressor NM23 provides a novel mechanism of GTPase regulation.Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14911-8. doi: 10.1073/pnas.96.26.14911.
1259 RasGRF2 promotes migration and invasion of colorectal cancer cells by modulating expression of MMP9 through Src/Akt/NF-B pathway.Cancer Biol Ther. 2019;20(4):435-443. doi: 10.1080/15384047.2018.1529117. Epub 2018 Oct 25.
1260 Expression of LC3B and FIP200/Atg17 in brain metastases of breast cancer.J Neurooncol. 2018 Nov;140(2):237-248. doi: 10.1007/s11060-018-2959-5. Epub 2018 Aug 9.
1261 Pan-cancer EMT-signature identifies RBM47 down-regulation during colorectal cancer progression.Sci Rep. 2017 Jul 5;7(1):4687. doi: 10.1038/s41598-017-04234-2.
1262 RCAN1-4 is a thyroid cancer growth and metastasis suppressor.JCI Insight. 2017 Mar 9;2(5):e90651. doi: 10.1172/jci.insight.90651.
1263 Integrated mRNA and lncRNA expression profiling for exploring metastatic biomarkers of human intrahepatic cholangiocarcinoma.Am J Cancer Res. 2017 Mar 1;7(3):688-699. eCollection 2017.
1264 FAM134B induces tumorigenesis and epithelial-to-mesenchymal transition via Akt signaling in hepatocellular carcinoma.Mol Oncol. 2019 Apr;13(4):792-810. doi: 10.1002/1878-0261.12429. Epub 2019 Jan 24.
1265 Regulator of G protein signaling 19 suppresses Ras-induced neoplastic transformation and tumorigenesis.Cancer Lett. 2013 Oct 1;339(1):33-41. doi: 10.1016/j.canlet.2013.07.025. Epub 2013 Jul 30.
1266 RGS22, a novel cancer/testis antigen, inhibits epithelial cell invasion and metastasis.Clin Exp Metastasis. 2011 Aug;28(6):541-9. doi: 10.1007/s10585-011-9390-z. Epub 2011 May 1.
1267 Over-expression of regulator of G protein signaling 5 promotes tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma cells.J Surg Oncol. 2013 Sep;108(3):192-6. doi: 10.1002/jso.23367. Epub 2013 Jul 19.
1268 Reduced expression of epidermal growth factor receptor related protein in gastric cancer.Gut. 2005 Feb;54(2):201-6. doi: 10.1136/gut.2003.027078.
1269 Arkadia regulates tumor metastasis by modulation of the TGF- pathway.Cancer Res. 2013 Mar 15;73(6):1800-10. doi: 10.1158/0008-5472.CAN-12-1916. Epub 2013 Mar 6.
1270 RUNX1T1: a novel predictor of liver metastasis in primary pancreatic endocrine neoplasms.Pancreas. 2011 May;40(4):627-33. doi: 10.1097/MPA.0b013e3182152bda.
1271 S100A4 promotes invasion and angiogenesis in breast cancer MDA-MB-231 cells by upregulating matrix metalloproteinase-13.Acta Biochim Pol. 2012;59(4):593-8. Epub 2012 Nov 16.
1272 Promoter hyper-methylation of calcium binding proteins S100A6 and S100A2 in human prostate cancer.Prostate. 2005 Dec 1;65(4):322-30. doi: 10.1002/pros.20302.
1273 S100A7 Regulates Ovarian Cancer Cell Metastasis and Chemoresistance Through MAPK Signaling and Is Targeted by miR-330-5p.DNA Cell Biol. 2018 May;37(5):491-500. doi: 10.1089/dna.2017.3953. Epub 2018 Feb 27.
1274 A combination of the immunohistochemical markers CK7 and SATB2 is highly sensitive and specific for distinguishing primary ovarian mucinous tumors from colorectal and appendiceal metastases.Mod Pathol. 2019 Dec;32(12):1834-1846. doi: 10.1038/s41379-019-0302-0. Epub 2019 Jun 25.
1275 RT-PCR for mammaglobin genes, MGB1 and MGB2, identifies breast cancer micrometastases in sentinel lymph nodes.Am J Clin Pathol. 2004 May;121(5):637-43. doi: 10.1309/MMAC-TXT5-5L8Q-TKC1.
1276 Gene expression accurately distinguishes liver metastases of small bowel and pancreas neuroendocrine tumors.Clin Exp Metastasis. 2014 Dec;31(8):935-44. doi: 10.1007/s10585-014-9681-2. Epub 2014 Sep 21.
1277 SENP2 suppresses epithelial-mesenchymal transition of bladder cancer cells through deSUMOylation of TGF-RI.Mol Carcinog. 2017 Oct;56(10):2332-2341. doi: 10.1002/mc.22687. Epub 2017 Jun 30.
1278 SEPT9_i1 regulates human breast cancer cell motility through cytoskeletal and RhoA/FAK signaling pathway regulation.Cell Death Dis. 2019 Sep 26;10(10):720. doi: 10.1038/s41419-019-1947-9.
1279 sFRP1 inhibits epithelial-mesenchymal transition in A549 human lung adenocarcinoma cell line.Cancer Biother Radiopharm. 2013 Sep;28(7):565-71. doi: 10.1089/cbr.2012.1453. Epub 2013 Jun 26.
1280 Mitochondrial Reprogramming Regulates Breast Cancer Progression.Clin Cancer Res. 2016 Jul 1;22(13):3348-60. doi: 10.1158/1078-0432.CCR-15-2456. Epub 2016 Feb 17.
1281 SPAS-1 (stimulator of prostatic adenocarcinoma-specific T cells)/SH3GLB2: A prostate tumor antigen identified by CTLA-4 blockade.Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3509-14. doi: 10.1073/pnas.0712269105. Epub 2008 Feb 26.
1282 Polymorphisms in MMP9 and SIPA1 are associated with increased risk of nodal metastases in early-stage cervical cancer.Gynecol Oncol. 2010 Mar;116(3):539-43. doi: 10.1016/j.ygyno.2009.09.037. Epub 2009 Nov 10.
1283 Increased expression of SLC46A3 to oppose the progression of hepatocellular carcinoma and its effect on sorafenib therapy.Biomed Pharmacother. 2019 Jun;114:108864. doi: 10.1016/j.biopha.2019.108864. Epub 2019 Apr 10.
1284 Distinguishing synchronous from metachronous manifestation of distant metastases: a prognostic feature in differentiated thyroid carcinoma.Eur J Nucl Med Mol Imaging. 2017 Feb;44(2):190-195. doi: 10.1007/s00259-016-3485-3. Epub 2016 Aug 16.
1285 SMAGP, a new small trans-membrane glycoprotein altered in cancer.Oncogene. 2004 Apr 22;23(19):3395-403. doi: 10.1038/sj.onc.1207469.
1286 Aberrant BAF57 signaling facilitates prometastatic phenotypes.Clin Cancer Res. 2013 May 15;19(10):2657-67. doi: 10.1158/1078-0432.CCR-12-3049. Epub 2013 Mar 14.
1287 G9a and histone deacetylases are crucial for Snail2-mediated E-cadherin repression and metastasis in hepatocellular carcinoma.Cancer Sci. 2019 Nov;110(11):3442-3452. doi: 10.1111/cas.14173. Epub 2019 Sep 19.
1288 Loss of sst2 somatostatin receptor gene expression in human pancreatic and colorectal cancer.Cancer Res. 1996 Apr 15;56(8):1823-7.
1289 A combination of GATA3 and SOX10 is useful for the diagnosis of metastatic triple-negative breast cancer.Hum Pathol. 2019 Mar;85:221-227. doi: 10.1016/j.humpath.2018.11.005. Epub 2018 Nov 20.
1290 LncSOX4 serves an oncogenic role in the tumorigenesis of epithelial ovarian cancer by promoting cell proliferation and inhibiting apoptosis.Mol Med Rep. 2018 Jun;17(6):8282-8288. doi: 10.3892/mmr.2018.8892. Epub 2018 Apr 18.
1291 The metastatic behavior of osteosarcoma by gene expression and cytogenetic analyses.Hum Pathol. 2013 Oct;44(10):2188-98. doi: 10.1016/j.humpath.2013.04.013. Epub 2013 Jul 8.
1292 Expression of PH-20 in normal and neoplastic breast tissue.J Surg Res. 2002 Apr;103(2):203-7. doi: 10.1006/jsre.2002.6351.
1293 SPARCL1 suppresses metastasis in prostate cancer.Mol Oncol. 2013 Dec;7(6):1019-30. doi: 10.1016/j.molonc.2013.07.008. Epub 2013 Jul 20.
1294 ECRG2 inhibits cancer cell migration, invasion and metastasis through the down-regulation of uPA/plasmin activity.Carcinogenesis. 2007 Nov;28(11):2274-81. doi: 10.1093/carcin/bgm140. Epub 2007 Jun 29.
1295 Spondin 2 promotes the proliferation, migration and invasion of gastric cancer cells.J Cell Mol Med. 2020 Jan;24(1):98-113. doi: 10.1111/jcmm.14618. Epub 2019 Nov 5.
1296 Small proline rich protein 2a in benign and malignant liver disease.Hepatology. 2014 Mar;59(3):1130-43. doi: 10.1002/hep.26889. Epub 2014 Jan 27.
1297 SPSB3 targets SNAIL for degradation in GSK-3 phosphorylation-dependent manner and regulates metastasis.Oncogene. 2018 Feb 8;37(6):768-776. doi: 10.1038/onc.2017.370. Epub 2017 Oct 23.
1298 SPZ1 is critical for chemoresistance and aggressiveness in drug-resistant breast cancer cells.Biochem Pharmacol. 2018 Oct;156:43-51. doi: 10.1016/j.bcp.2018.07.046. Epub 2018 Aug 1.
1299 SRSF5: a novel marker for small-cell lung cancer and pleural metastatic cancer.Lung Cancer. 2016 Sep;99:57-65. doi: 10.1016/j.lungcan.2016.05.018. Epub 2016 May 26.
1300 Splicing factor SRSF6 promotes hyperplasia of sensitized skin.Nat Struct Mol Biol. 2014 Feb;21(2):189-97. doi: 10.1038/nsmb.2756. Epub 2014 Jan 19.
1301 Clinical impact of molecular and cytogenetic findings in synovial sarcoma.Genes Chromosomes Cancer. 2001 Aug;31(4):362-72. doi: 10.1002/gcc.1155.
1302 Cancer/testis antigen expression in human mesenchymal stem cells: down-regulation of SSX impairs cell migration and matrix metalloproteinase 2 expression.Cancer Res. 2005 Mar 15;65(6):2207-15. doi: 10.1158/0008-5472.CAN-04-1882.
1303 STAT5 expression correlates with recurrence and survival in melanoma patients treated with interferon-.Melanoma Res. 2018 Jun;28(3):204-210. doi: 10.1097/CMR.0000000000000435.
1304 STIM1 silencing inhibits the migration and invasion of A549 cells.Mol Med Rep. 2017 Sep;16(3):3283-3289. doi: 10.3892/mmr.2017.7010. Epub 2017 Jul 15.
1305 Association between LKB1 expression and prognosis of patients with solid tumours: an updated systematic review and meta-analysis.BMJ Open. 2019 Aug 5;9(8):e027185. doi: 10.1136/bmjopen-2018-027185.
1306 miR-199b-5p-Stonin 2 axis regulates metastases and epithelial-to-mesenchymal transition of papillary thyroid carcinoma.IUBMB Life. 2019 Jan;71(1):28-40. doi: 10.1002/iub.1889. Epub 2018 Oct 16.
1307 SYNJ2BP promotes the degradation of PTEN through the lysosome-pathway and enhances breast tumor metastasis via PI3K/AKT/SNAI1 signaling.Oncotarget. 2017 Sep 19;8(52):89692-89706. doi: 10.18632/oncotarget.21058. eCollection 2017 Oct 27.
1308 TAB3 upregulates Survivin expression to promote colorectal cancer invasion and metastasis by binding to the TAK1-TRAF6 complex.Oncotarget. 2017 Nov 18;8(63):106565-106576. doi: 10.18632/oncotarget.22497. eCollection 2017 Dec 5.
1309 MHC class I antigen processing pathway defects, ras mutations and disease stage in colorectal carcinoma.Int J Cancer. 2004 Mar 20;109(2):265-73. doi: 10.1002/ijc.11681.
1310 Microbiomic subprofiles and MDR1 promoter methylation in head and neck squamous cell carcinoma.Hum Mol Genet. 2012 Apr 1;21(7):1557-65. doi: 10.1093/hmg/ddr593. Epub 2011 Dec 15.
1311 Prognostic significance of expression of epithelial-mesenchymal transition driver brachyury in breast cancer and its association with subtype and characteristics.Oncol Lett. 2018 Jan;15(1):1037-1045. doi: 10.3892/ol.2017.7402. Epub 2017 Nov 14.
1312 C8orf4 is a transforming growth factor B induced transcript downregulated in metastatic colon cancer.Int J Cancer. 2004 Aug 10;111(1):72-5. doi: 10.1002/ijc.20235.
1313 Down-regulation of ZIP4 by RNA interference inhibits pancreatic cancer growth and increases the survival of nude mice with pancreatic cancer xenografts.Clin Cancer Res. 2009 Oct 1;15(19):5993-6001. doi: 10.1158/1078-0432.CCR-09-0557. Epub 2009 Sep 15.
1314 Aberrant expression of trefoil factor 3 is associated with colorectal carcinoma metastasis.J Cancer Res Ther. 2013 Jul-Sep;9(3):376-80. doi: 10.4103/0973-1482.119308.
1315 A transcriptional regulatory role of the THAP11-HCF-1 complex in colon cancer cell function.Mol Cell Biol. 2012 May;32(9):1654-70. doi: 10.1128/MCB.06033-11. Epub 2012 Feb 27.
1316 Loss of TIMP3 by promoter methylation of Sp1 binding site promotes oral cancer metastasis.Cell Death Dis. 2019 Oct 17;10(11):793. doi: 10.1038/s41419-019-2016-0.
1317 Tetraspan TM4SF5-dependent direct activation of FAK and metastatic potential of hepatocarcinoma cells.J Cell Sci. 2012 Dec 15;125(Pt 24):5960-73. doi: 10.1242/jcs.100586. Epub 2012 Oct 17.
1318 The association of the angiopoietin/Tie-2 system with the development of metastasis and leukocyte migration in neuroendocrine tumors.Endocr Relat Cancer. 2010 Oct 5;17(4):897-908. doi: 10.1677/ERC-10-0020. Print 2010 Dec.
1319 TMED3 promotes cell proliferation and motility in breast cancer and is negatively modulated by miR-188-3p.Cancer Cell Int. 2019 Mar 29;19:75. doi: 10.1186/s12935-019-0791-4. eCollection 2019.
1320 Transmembrane protein 106A is silenced by promoter region hypermethylation and suppresses gastric cancer growth by inducing apoptosis.J Cell Mol Med. 2014 Aug;18(8):1655-66. doi: 10.1111/jcmm.12352. Epub 2014 Jun 28.
1321 Methylation of TMEM176A is an independent prognostic marker and is involved in human colorectal cancer development.Epigenetics. 2017 Jul 3;12(7):575-583. doi: 10.1080/15592294.2017.1341027. Epub 2017 Jul 5.
1322 Expression and purification of a rapidly degraded protein, TMEM8B-a, in mammalian cell line.Protein Expr Purif. 2018 Nov;151:38-45. doi: 10.1016/j.pep.2018.06.002. Epub 2018 Jun 8.
1323 Metastatic susceptibility locus, an 8p hot-spot for tumour progression disrupted in colorectal liver metastases: 13 candidate genes examined at the DNA, mRNA and protein level.BMC Cancer. 2008 Jul 1;8:187. doi: 10.1186/1471-2407-8-187.
1324 Expression of decoy receptor 3 in liver tissue microarrays.Natl Med J India. 2008 Nov-Dec;21(6):275-8.
1325 ASPP2 suppresses squamous cell carcinoma via RelA/p65-mediated repression of p63.Proc Natl Acad Sci U S A. 2013 Oct 29;110(44):17969-74. doi: 10.1073/pnas.1309362110. Epub 2013 Oct 14.
1326 StarD13 3'-untranslated region functions as a ceRNA for TP53INP1 in prohibiting migration and invasion of breast cancer cells by regulating miR-125b activity.Eur J Cell Biol. 2018 Jan;97(1):23-31. doi: 10.1016/j.ejcb.2017.11.002. Epub 2017 Nov 11.
1327 TPPP3 Promotes Cell Proliferation, Invasion and Tumor Metastasis via STAT3/ Twist1 Pathway in Non-Small-Cell Lung Carcinoma.Cell Physiol Biochem. 2018;50(5):2004-2016. doi: 10.1159/000494892. Epub 2018 Nov 7.
1328 TRAF4 overexpression is a common characteristic of human carcinomas.Oncogene. 2007 Jan 4;26(1):142-7. doi: 10.1038/sj.onc.1209762. Epub 2006 Jun 26.
1329 TRAP1 downregulation in human ovarian cancer enhances invasion and epithelial-mesenchymal transition.Cell Death Dis. 2016 Dec 15;7(12):e2522. doi: 10.1038/cddis.2016.400.
1330 Knockdown of TRB3 induces apoptosis in human lung adenocarcinoma cells through regulation of Notch 1 expression.Mol Med Rep. 2013 Jul;8(1):47-52. doi: 10.3892/mmr.2013.1453. Epub 2013 Apr 30.
1331 TRIM2 is a novel promoter of human colorectal cancer.Scand J Gastroenterol. 2019 Feb;54(2):210-218. doi: 10.1080/00365521.2019.1575463. Epub 2019 Mar 27.
1332 TRIM65 triggers -catenin signaling via ubiquitylation of Axin1 to promote hepatocellular carcinoma.J Cell Sci. 2017 Sep 15;130(18):3108-3115. doi: 10.1242/jcs.206623. Epub 2017 Jul 28.
1333 NF-kappa B genes have a major role in inflammatory breast cancer.BMC Cancer. 2008 Feb 4;8:41. doi: 10.1186/1471-2407-8-41.
1334 Tspan8 is expressed in breast cancer and regulates E-cadherin/catenin signalling and metastasis accompanied by increased circulating extracellular vesicles.J Pathol. 2019 Aug;248(4):421-437. doi: 10.1002/path.5281. Epub 2019 Jun 18.
1335 Occludin is a direct target of thyroid transcription factor-1 (TTF-1/NKX2-1).J Biol Chem. 2012 Aug 17;287(34):28790-801. doi: 10.1074/jbc.M112.367987. Epub 2012 Jul 2.
1336 Changes in Vasodilator-Stimulated Phosphoprotein Phosphorylation, Profilin-1, and Cofilin-1 in Accreta and Protection by DHA.Reprod Sci. 2019 Jun;26(6):757-765. doi: 10.1177/1933719118792095. Epub 2018 Aug 9.
1337 Levels of the Autophagy-Related 5 Protein Affect Progression and Metastasis of Pancreatic Tumors in Mice.Gastroenterology. 2019 Jan;156(1):203-217.e20. doi: 10.1053/j.gastro.2018.09.053. Epub 2018 Oct 6.
1338 BCL6B expression in hepatocellular carcinoma and its efficacy in the inhibition of liver damage and fibrogenesis.Oncotarget. 2015 Aug 21;6(24):20252-65. doi: 10.18632/oncotarget.3857.
1339 Knockdown of Bone Morphogenetic Proteins Type 1a Receptor (BMPR1a) in Breast Cancer Cells Protects Bone from Breast Cancer-Induced Osteolysis by Suppressing RANKL Expression.Cell Physiol Biochem. 2018;45(5):1759-1771. doi: 10.1159/000487784. Epub 2018 Feb 23.
1340 Single-nucleotide polymorphism-mass array reveals commonly deleted regions at 3p22 and 3p14.2 associate with poor clinical outcome in esophageal squamous cell carcinoma.Int J Cancer. 2008 Aug 15;123(4):826-30. doi: 10.1002/ijc.23577.
1341 Clinical and pathological significance of Homo sapiens ceramide synthase 2 (CerS-2) in diverse human cancers.Biosci Rep. 2019 May 7;39(5):BSR20181743. doi: 10.1042/BSR20181743. Print 2019 May 31.
1342 Nucleoside Diphosphate Kinase Escalates A-to-C Mutations in MutT-Deficient Strains of Escherichia coli.J Bacteriol. 2019 Dec 6;202(1):e00567-19. doi: 10.1128/JB.00567-19. Print 2019 Dec 6.
1343 DDX49 is a novel biomarker and therapeutic target for lung cancer metastases.J Cell Mol Med. 2020 Jan;24(1):1141-1145. doi: 10.1111/jcmm.14734. Epub 2019 Nov 20.
1344 Significance of ELF3 mRNA expression for detection of lymph node metastases of colorectal cancer.Anticancer Res. 2012 Sep;32(9):3753-8.
1345 EPB41L5 is Associated With the Metastatic Potential of Low-grade Pancreatic Neuroendocrine Tumors.Cancer Genomics Proteomics. 2019 Sep-Oct;16(5):309-318. doi: 10.21873/cgp.20136.
1346 GNA13 expression promotes drug resistance and tumor-initiating phenotypes in squamous cell cancers.Oncogene. 2018 Mar;37(10):1340-1353. doi: 10.1038/s41388-017-0038-6. Epub 2017 Dec 19.
1347 HJURP Promotes Epithelial-to-Mesenchymal Transition via Upregulating SPHK1 in Hepatocellular Carcinoma.Int J Biol Sci. 2019 May 7;15(6):1139-1147. doi: 10.7150/ijbs.30904. eCollection 2019.
1348 Intrabiliary metastases in colorectal cancer: a systematic review.J Hepatobiliary Pancreat Sci. 2019 Jul;26(7):270-280. doi: 10.1002/jhbp.635. Epub 2019 Jun 10.
1349 Clinical significance and prognostic relevance of KRAS, BRAF, PI3K and TP53 genetic mutation analysis for resectable and unresectable colorectal liver metastases: A systematic review of the current evidence.Surg Oncol. 2018 Jun;27(2):280-288. doi: 10.1016/j.suronc.2018.05.012. Epub 2018 May 8.
1350 Unconventional myosin VIIA promotes melanoma progression.J Cell Sci. 2018 Feb 22;131(4):jcs209924. doi: 10.1242/jcs.209924.
1351 Hypoxia and loss of PHD2 inactivate stromal fibroblasts to decrease tumour stiffness and metastasis.EMBO Rep. 2015 Oct;16(10):1394-408. doi: 10.15252/embr.201540107. Epub 2015 Aug 31.
1352 Blocking podoplanin suppresses growth and pulmonary metastasis of human malignant melanoma.BMC Cancer. 2019 Jun 17;19(1):599. doi: 10.1186/s12885-019-5808-9.
1353 Caveolin-1 promotes invasion and metastasis by upregulating Pofut1 expression in mouse hepatocellular carcinoma.Cell Death Dis. 2019 Jun 17;10(7):477. doi: 10.1038/s41419-019-1703-1.
1354 Twist on a classic: vitamin D and hypercalcaemia of malignancy.BMJ Case Rep. 2017 Nov 23;2017:bcr2017220819. doi: 10.1136/bcr-2017-220819.
1355 Deficiency of the adrenomedullin-RAMP3 system suppresses metastasis through the modification of cancer-associated fibroblasts.Oncogene. 2020 Feb;39(9):1914-1930. doi: 10.1038/s41388-019-1112-z. Epub 2019 Nov 21.
1356 Enhanced intratumoral expression of RNF2 is a favorable prognostic factor for patients with cutaneous melanoma?.Oncotarget. 2018 Apr 3;9(25):17656-17663. doi: 10.18632/oncotarget.24825. eCollection 2018 Apr 3.
1357 Novel role of Snail 1 in promoting tumor neoangiogenesis.Biosci Rep. 2019 May 10;39(5):BSR20182161. doi: 10.1042/BSR20182161. Print 2019 May 31.
1358 BAG3-mediated miRNA let-7g and let-7i inhibit proliferation and enhance apoptosis of human esophageal carcinoma cells by targeting the drug transporter ABCC10.Cancer Lett. 2016 Feb 1;371(1):125-33. doi: 10.1016/j.canlet.2015.11.031. Epub 2015 Dec 3.