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ClinicalTrials.gov (NCT01738555) A Safety and Efficacy Study of Amdoxovir in HIV-1 Treatment-experienced Subjects. U.S. National Institutes of Health.
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ClinicalTrials.gov (NCT04749368) Study to Investigate the Safety and Efficacy of BRII-835 and BRII-179 Combination Therapy Treating Chronic HBV Infection. U.S. National Institutes of Health.
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ClinicalTrials.gov (NCT01779505) A Phase 1a Trial Assessing the Safety, Tolerability, and Immunogenicity of GS-4774 (GI-13020) at Various Dose Levels and Regimens in Healthy Adults. U.S. National Institutes of Health.
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ClinicalTrials.gov (NCT03866187) A Study to Evaluate the Reactogenicity, Safety, Immunogenicity and Efficacy of GlaxoSmithKline (GSK) Biologicals' HBV (Hepatitis B Virus) Viral Vector Vaccines and Adjuvanted Proteins Vaccine (GSK3528869A) in Adult Patients With Chronic Hepatitis B Infection.. U.S. National Institutes of Health.
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ClinicalTrials.gov (NCT03463369) A First-In-Human Study to Evaluate Safety, Tolerability, Reactogenicity, and Immunogenicity of JNJ-64300535, a DNA Vaccine, Administered by Electroporation-Mediated Intramuscular Injection, in Participants With Chronic Hepatitis B Who Are on Stable Nucleos(t)Ide Therapy and Virologically Suppressed. U.S. National Institutes of Health.
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The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
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Diabetes Mellitus, Nonalcoholic Fatty Liver Disease, and Conjugated Linoleic Acid (Omega 6): What Is the Link?.J Diabetes Res. 2019 Apr 8;2019:5267025. doi: 10.1155/2019/5267025. eCollection 2019.
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Tumor Necrosis Factor Receptor-Associated Factor 6 Promotes Hepatocarcinogenesis by Interacting With Histone Deacetylase 3 to Enhance c-Myc Gene Expression and Protein Stability.Hepatology. 2020 Jan;71(1):148-163. doi: 10.1002/hep.30801. Epub 2019 Aug 7.
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Role of Functional IFNL4, IFNLR1, IFNA, IFNAR2 Polymorphisms in Hepatitis B virus-related liver disease in Han Chinese population.J Viral Hepat. 2018 Mar;25(3):306-313. doi: 10.1111/jvh.12817. Epub 2017 Nov 29.
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The potential role of interleukin-37 in infectious diseases.Int Rev Immunol. 2020;39(1):3-10. doi: 10.1080/08830185.2019.1677644. Epub 2019 Oct 21.
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Correlation of TLR1-10 expression in peripheral blood mononuclear cells with chronic hepatitis B and chronic hepatitis B-related liver failure.Hum Immunol. 2010 Oct;71(10):950-6. doi: 10.1016/j.humimm.2010.07.013. Epub 2010 Jul 24.
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Boosting of Hepatitis B Virus-Specific T Cell Responses After Pegylated-Interferon--2a Therapy for Hepatitis B e Antigen-Positive Pediatric Patients.J Interferon Cytokine Res. 2019 Dec;39(12):740-751. doi: 10.1089/jir.2019.0042. Epub 2019 Jul 18.
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IPS-1 polymorphisms in regulating interferon response in HBV infection.Biosci Trends. 2019 May 12;13(2):130-135. doi: 10.5582/bst.2018.01304. Epub 2019 Mar 29.
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Evaluation of IL10, IL19 and IL20 gene polymorphisms and chronic hepatitis B infection outcome.Int J Immunogenet. 2008 Jun;35(3):255-64. doi: 10.1111/j.1744-313X.2008.00770.x.
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Risk of HBV reactivation in patients with B-cell lymphomas receiving obinutuzumab or rituximab immunochemotherapy.Blood. 2019 Jan 10;133(2):137-146. doi: 10.1182/blood-2018-04-848044. Epub 2018 Oct 19.
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Independent and additive effects of PNPLA3 and TM6SF2 polymorphisms on the development of non-B, non-C hepatocellular carcinoma.J Gastroenterol. 2019 May;54(5):427-436. doi: 10.1007/s00535-018-01533-x. Epub 2018 Nov 30.
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Plasma B-cell activating factor levels and polymorphisms in hepatitis B-related hepatocellular carcinoma: Clinical correlation and prognosis.Asian Pac J Allergy Immunol. 2021 Jun;39(2):136-144. doi: 10.12932/AP-250718-0376.
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The viral oncoprotein HBx of Hepatitis B virus promotes the growth of hepatocellular carcinoma through cooperating with the cellular oncoprotein RMP.Int J Biol Sci. 2014 Nov 18;10(10):1181-92. doi: 10.7150/ijbs.10275. eCollection 2014.
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Hepatitis B virus surface proteins accelerate cholestatic injury and tumor progression in Abcb4-knockout mice.Oncotarget. 2017 Feb 2;8(32):52560-52570. doi: 10.18632/oncotarget.15003. eCollection 2017 Aug 8.
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Brief Report: Relationship Between ABCC4 SNPs and Hepatitis B Virus Suppression During Tenofovir-Containing Antiretroviral Therapy in Patients With HIV/HBV Coinfection.J Acquir Immune Defic Syndr. 2019 Dec 1;82(4):421-425. doi: 10.1097/QAI.0000000000002136.
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Community Screening, Identification, and Referral to Primary Care, for Hepatitis C, B, and HIV Among Homeless Persons in Los Angeles.J Community Health. 2019 Dec;44(6):1044-1054. doi: 10.1007/s10900-019-00679-w.
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Relationship Between Vertebral Fractures, Bone Mineral Density, and Osteometabolic Profile in HIV and Hepatitis B and C-Infected Patients Treated With ART.Front Endocrinol (Lausanne). 2019 May 14;10:302. doi: 10.3389/fendo.2019.00302. eCollection 2019.
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TGF-1 down-regulation of NKG2D/DAP10 and 2B4/SAP expression on human NK cells contributes to HBV persistence.PLoS Pathog. 2012;8(3):e1002594. doi: 10.1371/journal.ppat.1002594. Epub 2012 Mar 15.
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Comparison of circulating, hepatocyte specific messenger RNA and microRNA as biomarkers for chronic hepatitis B and C.PLoS One. 2014 Mar 18;9(3):e92112. doi: 10.1371/journal.pone.0092112. eCollection 2014.
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Distribution and difference of APOBEC-induced mutations in the TpCpW context of HBV DNA between HCC and non-HCC.J Med Virol. 2020 Jan;92(1):53-61. doi: 10.1002/jmv.25572. Epub 2019 Aug 29.
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Hepatitis B virus X protein is capable of down-regulating protein level of host antiviral protein APOBEC3G.Sci Rep. 2017 Jan 18;7:40783. doi: 10.1038/srep40783.
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Serum apolipoprotein C3 levels are negatively associated with hepatitis B virus DNA in HBeAg-negative chronic hepatitis B patients.Lipids Health Dis. 2019 Jun 11;18(1):138. doi: 10.1186/s12944-019-1084-6.
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Maternal pre-pregnancy infection with hepatitis B virus and the risk of preterm birth: a population-based cohort study.Lancet Glob Health. 2017 Jun;5(6):e624-e632. doi: 10.1016/S2214-109X(17)30142-0.
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Elevation of highly up-regulated in liver cancer (HULC) by hepatitis B virus X protein promotes hepatoma cell proliferation via down-regulating p18.J Biol Chem. 2012 Jul 27;287(31):26302-11. doi: 10.1074/jbc.M112.342113. Epub 2012 Jun 8.
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Vaccination with a DNA vaccine encoding CD317-targeting HBs antigen elicits enhanced immunity in mice.Biochem Biophys Res Commun. 2018 Oct 12;504(4):865-870. doi: 10.1016/j.bbrc.2018.09.024. Epub 2018 Sep 13.
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BTLA/HVEM Signaling: Milestones in Research and Role in Chronic Hepatitis B Virus Infection.Front Immunol. 2019 Mar 29;10:617. doi: 10.3389/fimmu.2019.00617. eCollection 2019.
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Relationship between IFN-gamma gene polymorphism and susceptibility to intrauterine HBV infection.World J Gastroenterol. 2006 May 14;12(18):2928-31. doi: 10.3748/wjg.v12.i18.2928.
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Effects of vaccine-acquired polyclonal anti-HBs antibodies on the prevention of HBV infection of non-vaccine genotypes.J Gastroenterol. 2017 Sep;52(9):1051-1063. doi: 10.1007/s00535-017-1316-3. Epub 2017 Feb 14.
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CAPN2 acts as an indicator of hepatitis B virus to induce hepatic fibrosis.J Cell Biochem. 2020 Mar;121(3):2428-2436. doi: 10.1002/jcb.29465. Epub 2019 Nov 3.
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Genetic variants in cell death pathway genes and HBV-related hepatocellular carcinoma among a Chinese Han population.Apoptosis. 2017 Aug;22(8):1035-1047. doi: 10.1007/s10495-017-1385-z.
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Potential circulating biomarkers of circulating chemokines CCL5, MIP-1 and HA as for early detection of cirrhosis related to chronic HBV (hepatitis B virus) infection.BMC Infect Dis. 2019 Jun 14;19(1):523. doi: 10.1186/s12879-019-4130-0.
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Cyclin A2/E1 activation defines a hepatocellular carcinoma subclass with a rearrangement signature of replication stress.Nat Commun. 2018 Dec 7;9(1):5235. doi: 10.1038/s41467-018-07552-9.
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Ccne1 Overexpression Causes Chromosome Instability in Liver Cells and Liver Tumor Development in Mice.Gastroenterology. 2019 Jul;157(1):210-226.e12. doi: 10.1053/j.gastro.2019.03.016. Epub 2019 Mar 13.
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CD24 polymorphisms affect risk and progression of chronic hepatitis B virus infection.Hepatology. 2009 Sep;50(3):735-42. doi: 10.1002/hep.23047.
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Influence of Treg cells and HBV genotype on sustained response and drug resistance in the treatment with nucleoside drugs.Braz J Med Biol Res. 2017 Mar 2;50(3):e5796. doi: 10.1590/1414-431X20165796.
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Investigation on correlation between expression of CD58 molecule and severity of hepatitis B.World J Gastroenterol. 2006 Jul 14;12(26):4237-40. doi: 10.3748/wjg.v12.i26.4237.
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Hepatitis B virus core protein interacts with CD59 to promote complement-mediated liver inflammation during chronic hepatitis B virus infection.FEBS Lett. 2013 Oct 11;587(20):3314-20. doi: 10.1016/j.febslet.2013.08.044. Epub 2013 Sep 10.
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Asymmetric Modification of Hepatitis B Virus (HBV) Genomes by an Endogenous Cytidine Deaminase inside HBV Cores Informs a Model of Reverse Transcription.J Virol. 2018 Apr 27;92(10):e02190-17. doi: 10.1128/JVI.02190-17. Print 2018 May 15.
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Polypeptides coded for by the region pre-S and gene S of hepatitis B virus DNA with the receptor for polymerized human serum albumin: expression on hepatitis B particles produced in the HBeAg or anti-HBe phase of hepatitis B virus infection.J Immunol. 1986 May 1;136(9):3467-72.
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Increased expression of stathmin and elongation factor 1 in precancerous nodules with telomere dysfunction in hepatitis B viral cirrhotic patients.J Transl Med. 2014 May 31;12:154. doi: 10.1186/1479-5876-12-154.
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Promoter hypermethylation of p14 (ARF) , RB, and INK4 gene family in hepatocellular carcinoma with hepatitis B virus infection.Tumour Biol. 2014 Mar;35(3):2795-802. doi: 10.1007/s13277-013-1372-0. Epub 2013 Nov 20.
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Interleukin-34 mediated by hepatitis B virus X protein via CCAAT/enhancer-binding protein contributes to the proliferation and migration of hepatoma cells.Cell Prolif. 2019 Nov;52(6):e12703. doi: 10.1111/cpr.12703. Epub 2019 Oct 16.
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The metabolic responses to hepatitis B virus infection shed new light on pathogenesis and targets for treatment.Sci Rep. 2015 Feb 12;5:8421. doi: 10.1038/srep08421.
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Hepatitis B virus X protein induces IKK nuclear translocation via Akt-dependent phosphorylation to promote the motility of hepatocarcinoma cells.J Cell Physiol. 2012 Apr;227(4):1446-54. doi: 10.1002/jcp.22860.
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Predictive value of plasmacytoid dendritic cells and Toll-like receptor-9 regarding the treatment efficacy of interferon- in HBeAg-positive chronic hepatitis B patients.Exp Ther Med. 2019 Dec;18(6):4541-4546. doi: 10.3892/etm.2019.8161. Epub 2019 Nov 1.
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Zinc-dependent interaction between JAB1 and pre-S2 mutant large surface antigen of hepatitis B virus and its implications for viral hepatocarcinogenesis.J Virol. 2013 Dec;87(23):12675-84. doi: 10.1128/JVI.01497-13. Epub 2013 Sep 18.
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Hepatitis B Virus Blocks the CRE/CREB Complex and Prevents TLR9 Transcription and Function in Human B Cells.J Immunol. 2018 Oct 15;201(8):2331-2344. doi: 10.4049/jimmunol.1701726. Epub 2018 Sep 5.
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CXCL13-mediated recruitment of intrahepatic CXCR5(+)CD8(+) T cells favors viral control in chronic HBV infection.J Hepatol. 2020 Mar;72(3):420-430. doi: 10.1016/j.jhep.2019.09.031. Epub 2019 Oct 11.
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Nuclear-resident RIG-I senses viral replication inducing antiviral immunity.Nat Commun. 2018 Aug 10;9(1):3199. doi: 10.1038/s41467-018-05745-w.
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