DOT Name |
DOT ID |
UniProt ID |
Mode of Action |
REF |
Androgen receptor (AR)
|
OTUBKAZZ
|
ANDR_HUMAN
|
Decreases Response To Substance
|
[9] |
Very long chain fatty acid elongase 7 (ELOVL7)
|
OT89NYVC
|
ELOV7_HUMAN
|
Decreases Expression
|
[6] |
Bone morphogenetic protein receptor type-1B (BMPR1B)
|
OTGFN0OD
|
BMR1B_HUMAN
|
Decreases Expression
|
[6] |
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 (PLOD2)
|
OTKOZRZP
|
PLOD2_HUMAN
|
Decreases Expression
|
[6] |
RNA polymerase II elongation factor ELL2 (ELL2)
|
OTZJRTFM
|
ELL2_HUMAN
|
Decreases Expression
|
[6] |
Suppressor of cytokine signaling 2 (SOCS2)
|
OTBPNKJQ
|
SOCS2_HUMAN
|
Decreases Expression
|
[6] |
Transmembrane protease serine 2 (TMPRSS2)
|
OTN44YQ5
|
TMPS2_HUMAN
|
Decreases Expression
|
[6] |
ATP-binding cassette sub-family C member 4 (ABCC4)
|
OTO27PAL
|
MRP4_HUMAN
|
Decreases Expression
|
[6] |
Unconventional myosin-Ib (MYO1B)
|
OTGZUJ0I
|
MYO1B_HUMAN
|
Decreases Expression
|
[6] |
Kinesin heavy chain isoform 5C (KIF5C)
|
OT35570Y
|
KIF5C_HUMAN
|
Decreases Expression
|
[6] |
Transcription factor Maf (MAF)
|
OT1GR3IZ
|
MAF_HUMAN
|
Decreases Expression
|
[6] |
Solute carrier family 22 member 3 (SLC22A3)
|
OTQYGVXX
|
S22A3_HUMAN
|
Decreases Expression
|
[6] |
Insulin-like growth factor I (IGF1)
|
OTIIZR61
|
IGF1_HUMAN
|
Decreases Expression
|
[6] |
Tyrosine-protein kinase Lck (LCK)
|
OT883FG9
|
LCK_HUMAN
|
Decreases Expression
|
[6] |
Insulin-like growth factor 1 receptor (IGF1R)
|
OTXJIF13
|
IGF1R_HUMAN
|
Decreases Expression
|
[6] |
Microtubule-associated protein 2 (MAP2)
|
OT6UYT3X
|
MTAP2_HUMAN
|
Decreases Expression
|
[6] |
Plastin-2 (LCP1)
|
OTK61F2A
|
PLSL_HUMAN
|
Decreases Expression
|
[6] |
Kallikrein-2 (KLK2)
|
OT9RE37R
|
KLK2_HUMAN
|
Decreases Expression
|
[6] |
Zinc-alpha-2-glycoprotein (AZGP1)
|
OTPD9TDR
|
ZA2G_HUMAN
|
Decreases Expression
|
[6] |
Dipeptidyl peptidase 4 (DPP4)
|
OT16MVL9
|
DPP4_HUMAN
|
Decreases Expression
|
[6] |
Prostaglandin E2 receptor EP4 subtype (PTGER4)
|
OT2GBV06
|
PE2R4_HUMAN
|
Decreases Expression
|
[6] |
Phospholipase A2 group V (PLA2G5)
|
OTQRSKCZ
|
PA2G5_HUMAN
|
Decreases Expression
|
[6] |
Regulator of G-protein signaling 2 (RGS2)
|
OT0FSRW7
|
RGS2_HUMAN
|
Decreases Expression
|
[6] |
Retinaldehyde dehydrogenase 3 (ALDH1A3)
|
OT1C9NKQ
|
AL1A3_HUMAN
|
Decreases Expression
|
[6] |
Selenoprotein P (SELENOP)
|
OT02B8IR
|
SEPP1_HUMAN
|
Decreases Expression
|
[6] |
AF4/FMR2 family member 3 (AFF3)
|
OTR0705Z
|
AFF3_HUMAN
|
Decreases Expression
|
[6] |
Cysteine-rich secretory protein 3 (CRISP3)
|
OTBSWMPL
|
CRIS3_HUMAN
|
Decreases Expression
|
[6] |
Tumor protein D52 (TPD52)
|
OTPKSK43
|
TPD52_HUMAN
|
Decreases Expression
|
[6] |
Testican-1 (SPOCK1)
|
OTLTDGK7
|
TICN1_HUMAN
|
Decreases Expression
|
[6] |
Acyl-coenzyme A synthetase ACSM1, mitochondrial (ACSM1)
|
OT1TS9M9
|
ACSM1_HUMAN
|
Decreases Expression
|
[6] |
Ras GTPase-activating-like protein IQGAP2 (IQGAP2)
|
OTX2UA7P
|
IQGA2_HUMAN
|
Decreases Expression
|
[6] |
Glycine N-methyltransferase (GNMT)
|
OT0O2OQO
|
GNMT_HUMAN
|
Decreases Expression
|
[6] |
Ketimine reductase mu-crystallin (CRYM)
|
OTRGSR6B
|
CRYM_HUMAN
|
Decreases Expression
|
[6] |
Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase (ADPRM)
|
OTXE3X5J
|
ADPRM_HUMAN
|
Decreases Expression
|
[6] |
Protein GREB1 (GREB1)
|
OTU6ZA26
|
GREB1_HUMAN
|
Decreases Expression
|
[6] |
EF-hand calcium-binding domain-containing protein 12 (EFCAB12)
|
OT1QZJEI
|
EFC12_HUMAN
|
Decreases Expression
|
[6] |
Rho-related GTP-binding protein RhoU (RHOU)
|
OTERIAD4
|
RHOU_HUMAN
|
Decreases Expression
|
[6] |
Transient receptor potential cation channel subfamily M member 8 (TRPM8)
|
OT7ACGYK
|
TRPM8_HUMAN
|
Decreases Expression
|
[6] |
Alpha-protein kinase 2 (ALPK2)
|
OTWZZDQ9
|
ALPK2_HUMAN
|
Decreases Expression
|
[6] |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial (AADAT)
|
OTO68C3Y
|
AADAT_HUMAN
|
Decreases Expression
|
[6] |
Chondroitin sulfate N-acetylgalactosaminyltransferase 1 (CSGALNACT1)
|
OTBML9D9
|
CGAT1_HUMAN
|
Decreases Expression
|
[6] |
Homeobox protein Nkx-3.1 (NKX3-1)
|
OT0DO6ZU
|
NKX31_HUMAN
|
Decreases Expression
|
[6] |
Specifically androgen-regulated gene protein (C1ORF116)
|
OTPYEXDM
|
SARG_HUMAN
|
Decreases Expression
|
[6] |
ER degradation-enhancing alpha-mannosidase-like protein 3 (EDEM3)
|
OT4GJX9R
|
EDEM3_HUMAN
|
Decreases Expression
|
[6] |
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (ST6GALNAC1)
|
OT3JQD99
|
SIA7A_HUMAN
|
Decreases Expression
|
[6] |
Teneurin-1 (TENM1)
|
OTSKSU4V
|
TEN1_HUMAN
|
Decreases Expression
|
[6] |
Transmembrane and coiled-coil domain protein 3 (TMCC3)
|
OTAIQ6V6
|
TMCC3_HUMAN
|
Decreases Expression
|
[6] |
E3 ubiquitin-protein ligase NEURL1B (NEURL1B)
|
OT3BZWO8
|
NEU1B_HUMAN
|
Affects Expression
|
[7] |
Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10)
|
OTOKUXUH
|
ADA10_HUMAN
|
Affects Expression
|
[7] |
Integrin beta-1-binding protein 1 (ITGB1BP1)
|
OTVQFNGS
|
ITBP1_HUMAN
|
Affects Expression
|
[7] |
Sushi domain-containing protein 5 (SUSD5)
|
OTIMJGDH
|
SUSD5_HUMAN
|
Affects Expression
|
[7] |
GDP-mannose 4,6 dehydratase (GMDS)
|
OTWV79YD
|
GMDS_HUMAN
|
Affects Expression
|
[7] |
Polycomb protein EED (EED)
|
OTJFHCDF
|
EED_HUMAN
|
Decreases Expression
|
[10] |
Myc proto-oncogene protein (MYC)
|
OTPV5LUK
|
MYC_HUMAN
|
Decreases Expression
|
[11] |
Amyloid-beta precursor protein (APP)
|
OTKFD7R4
|
A4_HUMAN
|
Affects Expression
|
[7] |
Prostate-specific antigen (KLK3)
|
OTFGSBFJ
|
KLK3_HUMAN
|
Decreases Expression
|
[11] |
Beta-microseminoprotein (MSMB)
|
OTYORAJC
|
MSMB_HUMAN
|
Decreases Expression
|
[12] |
Keratin, type I cytoskeletal 19 (KRT19)
|
OTDGDQ75
|
K1C19_HUMAN
|
Affects Expression
|
[7] |
Annexin A4 (ANXA4)
|
OTUCRYXL
|
ANXA4_HUMAN
|
Affects Expression
|
[7] |
Poly polymerase 1 (PARP1)
|
OT310QSG
|
PARP1_HUMAN
|
Decreases Cleavage
|
[11] |
G2/mitotic-specific cyclin-B1 (CCNB1)
|
OT19S7E5
|
CCNB1_HUMAN
|
Decreases Expression
|
[10] |
Membrane cofactor protein (CD46)
|
OTQ8NWJD
|
MCP_HUMAN
|
Increases Expression
|
[13] |
Aspartate aminotransferase, cytoplasmic (GOT1)
|
OTZLM5UB
|
AATC_HUMAN
|
Affects Expression
|
[7] |
Midkine (MDK)
|
OTF24HKC
|
MK_HUMAN
|
Affects Expression
|
[7] |
Hepatocyte nuclear factor 1-beta (HNF1B)
|
OTSYIC3T
|
HNF1B_HUMAN
|
Affects Expression
|
[7] |
Small ribosomal subunit protein eS19 (RPS19)
|
OTBKGP48
|
RS19_HUMAN
|
Affects Expression
|
[7] |
Caspase-3 (CASP3)
|
OTIJRBE7
|
CASP3_HUMAN
|
Decreases Expression
|
[10] |
Cyclin-dependent kinase inhibitor 1B (CDKN1B)
|
OTNY5LLZ
|
CDN1B_HUMAN
|
Affects Expression
|
[7] |
Neurogenic locus notch homolog protein 1 (NOTCH1)
|
OTI1WADQ
|
NOTC1_HUMAN
|
Affects Expression
|
[7] |
Transcription factor SOX-9 (SOX9)
|
OTVDJFGN
|
SOX9_HUMAN
|
Affects Expression
|
[7] |
CCAAT/enhancer-binding protein alpha (CEBPA)
|
OTOM9OE4
|
CEBPA_HUMAN
|
Affects Expression
|
[7] |
Presenilin-1 (PSEN1)
|
OTKL39RT
|
PSN1_HUMAN
|
Affects Expression
|
[7] |
Presenilin-2 (PSEN2)
|
OTOW778B
|
PSN2_HUMAN
|
Affects Expression
|
[7] |
Hepatocyte nuclear factor 3-alpha (FOXA1)
|
OTEBY0TD
|
FOXA1_HUMAN
|
Affects Expression
|
[7] |
Ubiquitin-ribosomal protein eS31 fusion protein (RPS27A)
|
OTIIGGZ2
|
RS27A_HUMAN
|
Affects Expression
|
[7] |
Protein jagged-1 (JAG1)
|
OT3LGT6K
|
JAG1_HUMAN
|
Affects Expression
|
[7] |
Disintegrin and metalloproteinase domain-containing protein 17 (ADAM17)
|
OTTM6KRB
|
ADA17_HUMAN
|
Affects Expression
|
[7] |
Neurogenic locus notch homolog protein 2 (NOTCH2)
|
OTQ3Y9PA
|
NOTC2_HUMAN
|
Affects Expression
|
[7] |
Recombining binding protein suppressor of hairless (RBPJ)
|
OTD7CUG0
|
SUH_HUMAN
|
Affects Expression
|
[7] |
Histone acetyltransferase p300 (EP300)
|
OTL8QJDX
|
EP300_HUMAN
|
Affects Expression
|
[7] |
Peptidyl-prolyl cis-trans isomerase FKBP5 (FKBP5)
|
OT404F9K
|
FKBP5_HUMAN
|
Decreases Expression
|
[11] |
SNW domain-containing protein 1 (SNW1)
|
OTKWG3PS
|
SNW1_HUMAN
|
Affects Expression
|
[7] |
Transcription factor HES-1 (HES1)
|
OT8P19W2
|
HES1_HUMAN
|
Affects Expression
|
[7] |
Caspase-8 (CASP8)
|
OTA8TVI8
|
CASP8_HUMAN
|
Decreases Expression
|
[10] |
Polycomb protein SUZ12 (SUZ12)
|
OT655XF8
|
SUZ12_HUMAN
|
Decreases Expression
|
[10] |
Histone-lysine N-methyltransferase EZH2 (EZH2)
|
OTIEHTKW
|
EZH2_HUMAN
|
Decreases Expression
|
[10] |
Probable E3 ubiquitin-protein ligase DTX2 (DTX2)
|
OT7QLDU4
|
DTX2_HUMAN
|
Affects Expression
|
[7] |
E3 ubiquitin-protein ligase MIB1 (MIB1)
|
OT5C404P
|
MIB1_HUMAN
|
Affects Expression
|
[7] |
NF-kappa-B-activating protein (NKAP)
|
OT7K7I8Q
|
NKAP_HUMAN
|
Affects Expression
|
[7] |
Probable E3 ubiquitin-protein ligase DTX3 (DTX3)
|
OTSUUV9N
|
DTX3_HUMAN
|
Affects Expression
|
[7] |
Polypeptide N-acetylgalactosaminyltransferase 11 (GALNT11)
|
OTANT9E6
|
GLT11_HUMAN
|
Affects Expression
|
[7] |
Gamma-secretase subunit APH-1B (APH1B)
|
OTQHPTGC
|
APH1B_HUMAN
|
Affects Expression
|
[7] |
Nicastrin (NCSTN)
|
OT5QBTA4
|
NICA_HUMAN
|
Affects Expression
|
[7] |
Mastermind-like protein 1 (MAML1)
|
OTQA4DDN
|
MAML1_HUMAN
|
Affects Expression
|
[7] |
CREB-binding protein (CREBBP)
|
OTPA4QGM
|
CBP_HUMAN
|
Affects Expression
|
[7] |
Histone acetyltransferase KAT2B (KAT2B)
|
OTWQITWK
|
KAT2B_HUMAN
|
Affects Expression
|
[7] |
E3 ubiquitin-protein ligase MIB2 (MIB2)
|
OTJCC3HS
|
MIB2_HUMAN
|
Affects Expression
|
[7] |
Gamma-secretase subunit APH-1A (APH1A)
|
OT97F1TU
|
APH1A_HUMAN
|
Affects Expression
|
[7] |
p53 apoptosis effector related to PMP-22 (PERP)
|
OTP0YL53
|
PERP_HUMAN
|
Affects Expression
|
[7] |
E3 ubiquitin-protein ligase Itchy homolog (ITCH)
|
OTUOMKF5
|
ITCH_HUMAN
|
Affects Expression
|
[7] |
Mastermind-like protein 3 (MAML3)
|
OTZFV53Z
|
MAML3_HUMAN
|
Affects Expression
|
[7] |
Intraflagellar transport protein 74 homolog (IFT74)
|
OTZBFEDD
|
IFT74_HUMAN
|
Affects Expression
|
[7] |
RNA-binding protein 15 (RBM15)
|
OT8ZPGWF
|
RBM15_HUMAN
|
Affects Expression
|
[7] |
Msx2-interacting protein (SPEN)
|
OT37A2MD
|
MINT_HUMAN
|
Affects Expression
|
[7] |
Sphingosine 1-phosphate receptor 3 (S1PR3)
|
OTXBIYO8
|
S1PR3_HUMAN
|
Affects Expression
|
[7] |
GDP-fucose protein O-fucosyltransferase 1 (POFUT1)
|
OTOBJZIT
|
OFUT1_HUMAN
|
Affects Expression
|
[7] |
Notchless protein homolog 1 (NLE1)
|
OT1BV82K
|
NLE1_HUMAN
|
Affects Expression
|
[7] |
Gamma-secretase subunit PEN-2 (PSENEN)
|
OTJ7M7G9
|
PEN2_HUMAN
|
Affects Expression
|
[7] |
Protein sel-1 homolog 1 (SEL1L)
|
OTC0FB7T
|
SE1L1_HUMAN
|
Affects Expression
|
[7] |
Intraflagellar transport protein 172 homolog (IFT172)
|
OT12DW08
|
IF172_HUMAN
|
Affects Expression
|
[7] |
Neurogenic locus notch homolog protein 3 (NOTCH3)
|
OTMVVA7F
|
NOTC3_HUMAN
|
Affects Expression
|
[7] |
Protein jagged-2 (JAG2)
|
OTH7KRRF
|
JAG2_HUMAN
|
Affects Expression
|
[7] |
E3 ubiquitin-protein ligase DTX4 (DTX4)
|
OTGX30AO
|
DTX4_HUMAN
|
Affects Expression
|
[7] |
Epsin-1 (EPN1)
|
OT4Q1NIV
|
EPN1_HUMAN
|
Affects Expression
|
[7] |
Signal transducer and activator of transcription 3 (STAT3)
|
OTAAGKYZ
|
STAT3_HUMAN
|
Decreases Response To Substance
|
[14] |
Ephrin type-B receptor 4 (EPHB4)
|
OTKLPVXJ
|
EPHB4_HUMAN
|
Affects Response To Substance
|
[11] |
Interleukin-6 (IL6)
|
OTUOSCCU
|
IL6_HUMAN
|
Decreases Response To Substance
|
[14] |
------------------------------------------------------------------------------------ |
|
|
|
|