Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMAC698)

Drug Name
CORILAGIN Drug Info
Synonyms
Corilagin; 23094-69-1; CHEMBL449392; CHEBI:3884; TUSDEZXZIZRFGC-XIGLUPEJSA-N; Corillagin; Corilagin,(S); AC1Q6PBU; AC1L2K3M; (1s,19r,21s,22r,23r)-6,7,8,11,12,13,22,23-octahydroxy-3,16-dioxo-2,17,20-trioxatetracyclo[17.3.1.04,9.010,15]tricosa-4,6,8,10,12,14-hexaen-21-yl 3,4,5-trihydroxybenzoate; SCHEMBL329080; Corilagin, analytical standard; CTK4F0871; MolPort-020-005-758; b-D-Glucopyranose, cyclic3,6-[(1R)-4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate]1-(3,4,5-trihydroxybenzoate); ZINC4098612; BDBM50242279
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
73568
ChEBI ID
CHEBI:3884
CAS Number
CAS 2088321-44-0
TTD Drug ID
DMAC698

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Human immunodeficiency virus Reverse transcriptase (HIV RT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [4]
Nevirapine DM6HX9B Human immunodeficiency virus infection 1C62 Approved [5]
Zalcitabine DMH7MUV Human immunodeficiency virus infection 1C62 Approved [6]
Tenofovir DM1IS6U Chronic hepatitis B virus infection Approved [4]
Lamivudine DMI347A Chronic HBV infection 1E51.0Z Approved [7]
Abacavir DMMN36E Human immunodeficiency virus infection 1C62 Approved [8]
Delavirdine DM3NF5G Human immunodeficiency virus infection 1C62 Approved [7]
Efavirenz DMC0GSJ Human immunodeficiency virus infection 1C62 Approved [7]
Rilpivirine DMJ0QOW Human immunodeficiency virus infection 1C62 Approved [9]
Etravirine DMGV8QU Human immunodeficiency virus-1 infection 1C62 Approved [10]
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Drug(s) Targeting Squalene monooxygenase (SQLE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Naftifine DMHVBG1 Dermatomycosis EA60 Approved [11]
Tolnaftate DM28MU7 Dermatophytosis 1F28.2 Approved [12]
Epigallocatechin gallate DMCGWBJ Hepatic fibrosis DB93.0 Phase 3 [1]
FR-194738 DMNACIV Hypercholesterolaemia 5C80.0 Terminated [13]
SDZ-87-469 DMBY6CQ Coronary artery disease BA80 Terminated [12]
NB-598 DMJVTQN N. A. N. A. Terminated [14]
ELLAGIC ACID DMX8BS5 Discovery agent N.A. Investigative [1]
1,2,3,4,6-penta-O-galloyl-beta-D-glucose DMTK650 Discovery agent N.A. Investigative [1]
Pedunculagin DMKLRCX Discovery agent N.A. Investigative [1]
ETHYLGALLATE DMJ6PB8 Discovery agent N.A. Investigative [1]
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Drug(s) Affected By Tumor necrosis factor (TNF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [15]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [16]
Fructose DM43AN2 Vomiting MD90 Approved [17]
Ketoprofen DMRKXPT Bursitis Approved [17]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [18]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [19]
Baclofen DM0QV1J Multiple sclerosis 8A40 Approved [20]
Gefitinib DM15F0X Colon adenocarcinoma Approved [21]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [22]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [23]
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Drug(s) Affected By Interleukin-6 (IL6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [24]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [25]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [26]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [27]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [28]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [29]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [23]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [30]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [31]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
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Drug(s) Affected By Nuclear factor NF-kappa-B p105 subunit (NFKB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [32]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [33]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [34]
Gefitinib DM15F0X Colon adenocarcinoma Approved [35]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [36]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [37]
Methotrexate DM2TEOL Anterior urethra cancer Approved [38]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [39]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [40]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
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Drug(s) Affected By RAC-alpha serine/threonine-protein kinase (AKT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Capivasertib DM9SKW8 Breast cancer 2C60-2C65 Approved [42]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [43]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [44]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [45]
Gefitinib DM15F0X Colon adenocarcinoma Approved [46]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [47]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [48]
Selenium DM25CGV N. A. N. A. Approved [49]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [50]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [51]
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Drug(s) Affected By Nitric oxide synthase, inducible (NOS2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [52]
Indomethacin DMSC4A7 Bursitis Approved [38]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [53]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [54]
Methotrexate DM2TEOL Anterior urethra cancer Approved [55]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [56]
Quercetin DM3NC4M Obesity 5B81 Approved [57]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [58]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [59]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [60]
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Drug(s) Affected By Prostaglandin G/H synthase 2 (PTGS2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Eicosapentaenoic acid/docosa-hexaenoic acid DMMUCG4 Hypertriglyceridemia 5C80.1 Approved [61]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [62]
Gamolenic acid DMQN30Z Allergy 4A80-4A85 Approved [63]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [64]
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [65]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [66]
Ibandronate DM0QZBN Hypercalcaemia 5B91.0 Approved [67]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [68]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [69]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [70]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Human immunodeficiency virus Reverse transcriptase (HIV RT) TT84ETX POL_HV1B1 Inhibitor [2]
Squalene monooxygenase (SQLE) TTE14XG ERG1_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Interleukin-6 (IL6) OTUOSCCU IL6_HUMAN Gene/Protein Processing [3]
Nitric oxide synthase, inducible (NOS2) OTKKIOJ1 NOS2_HUMAN Gene/Protein Processing [3]
Nuclear factor NF-kappa-B p105 subunit (NFKB1) OTNRRD8I NFKB1_HUMAN Gene/Protein Processing [3]
Prostaglandin G/H synthase 2 (PTGS2) OT75U9M4 PGH2_HUMAN Gene/Protein Processing [3]
RAC-alpha serine/threonine-protein kinase (AKT1) OT8H2YY7 AKT1_HUMAN Gene/Protein Processing [3]
Tumor necrosis factor (TNF) OT4IE164 TNFA_HUMAN Gene/Protein Processing [3]

References

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