Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMYNMDP)

Drug Name
Tocainide Drug Info
Synonyms
Taquidil; Tocainida; Tocainidum; Tonocard; Astra W 36095; Tocainida [INN-Spanish]; Tocainidum [INN-Latin]; W-36095; Tocainide (USAN/INN); Tocainide [USAN:BAN:INN]; Alanyl-2,6-xylidide; N-(2,6-dimethylphenyl)alaninamide; (-)-2-Amino-N-(2,6-dimethylphenyl)propanamide; 2-AMINO-N-(2,6-DIMETHYLPHENYL)PROPANAMIDE; 2-Amino-2',6'-propionoxylidide; 2-Amino-N-(2,6-dimethylphenyl)propionamid
Indication
Disease Entry ICD 11 Status REF
Ventricular arrhythmias BC71 Approved [1]
Therapeutic Class
Antiarrhythmic Agents
Cross-matching ID
PubChem CID
38945
ChEBI ID
CHEBI:9611
CAS Number
CAS 41708-72-9
TTD Drug ID
DMYNMDP
INTEDE Drug ID
DR1607

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DME
DOT
Drug Status:
Approved Drug(s)
Discontinued Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting E3 ubiquitin-protein ligase COP1 (RFWD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [2]
Procainamide DMNMXR8 Ventricular arrhythmias BC71 Approved [2]
Propafenone DMPIBJK Tachyarrhythmias BC71 Approved [2]
Flecainide DMSQDLE Tachyarrhythmias BC71 Approved [2]
Barucainide DMTMS3L Heart arrhythmia BC65 Terminated [5]
Drug(s) Metabolized By Cytochrome P450 1A2 (CYP1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [6]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [7]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [8]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [9]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [10]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [11]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [12]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [13]
Verapamil DMA7PEW Angina pectoris BA40 Approved [14]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [15]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Potassium voltage-gated channel subfamily KQT member 1 (KCNQ1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Propranolol DM79NTF Angina pectoris BA40 Approved [16]
Atenolol DMNKG1Z Angina pectoris BA40 Approved [16]
Quinidine DMLPICK N. A. N. A. Approved [4]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [17]
Bupivacaine DM4PRFC Anaesthesia 9A78.6 Approved [18]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [19]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [20]
Mepivacaine DMH2NMY Analgesia MB40.8 Approved [18]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [21]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [21]
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Drug(s) Affected By Sodium channel protein type 5 subunit alpha (SCN5A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Disopyramide DM5SYZP Long QT syndrome BC65.0 Approved [4]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [22]
Flecainide DMSQDLE Tachyarrhythmias BC71 Approved [23]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [24]
Meloxicam DM2AR7L Arthritis FA20 Approved [25]
Quercetin DM3NC4M Obesity 5B81 Approved [26]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [27]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [28]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Retigabine DMGNYIH Behcet disease 4A62 Approved [30]
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Drug(s) Affected By Cytochrome P450 2D6 (CYP2D6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [31]
Paliperidone DM7NPJS Psychotic disorder 6A20-6A25 Approved [32]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [33]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [34]
Oxatomide DM1F42Z Hay fever CA08.00 Approved [35]
Cinacalcet DMCX0K3 Hyperparathyroidism 5A51 Approved [36]
Capsaicin DMGMF6V Back pain ME84.Z Approved [37]
Pentamidine DMHZJCG African trypanosomiasis 1F51 Approved [38]
Quinidine DMLPICK N. A. N. A. Approved [39]
Buprenorphine DMPRI8G Opioid dependence 6C43.2Z Approved [40]
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Drug(s) Affected By Potassium voltage-gated channel subfamily E member 1 (KCNE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [41]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [42]
Pentobarbital DMFNH7L Brain ischaemia 8B1Z Approved [43]
Verapamil DMA7PEW Angina pectoris BA40 Approved [4]
Propranolol DM79NTF Angina pectoris BA40 Approved [4]
Diltiazem DMAI7ZV Angina pectoris BA40 Approved [4]
Sotalol DML60TN Sinus rhythm disorder BC9Y Approved [4]
Quinidine DMLPICK N. A. N. A. Approved [4]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [4]
Atenolol DMNKG1Z Angina pectoris BA40 Approved [4]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Potassium voltage-gated channel subfamily H member 2 (KCNH2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Metoclopramide DMFA5MY Nausea MD90 Approved [44]
Quinidine DMLPICK N. A. N. A. Approved [45]
Verapamil DMA7PEW Angina pectoris BA40 Approved [46]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [47]
Clarithromycin DM4M1SG Acute maxillary sinusitis Approved [47]
Disopyramide DM5SYZP Long QT syndrome BC65.0 Approved [48]
Propranolol DM79NTF Angina pectoris BA40 Approved [49]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [50]
Dofetilide DMPN1TW Sinus rhythm disorder BC9Y Approved [51]
Flecainide DMSQDLE Tachyarrhythmias BC71 Approved [47]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
E3 ubiquitin-protein ligase COP1 (RFWD2) TT05DLS COP1_HUMAN Modulator [2]
Voltage-gated sodium channel (Nav) TTIG65Q NOUNIPROTAC Modulator [2]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 1A2 (CYP1A2) Main DME DEJGDUW CP1A2_HUMAN Substrate [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Cytochrome P450 2D6 (CYP2D6) OTZJC802 CP2D6_HUMAN Drug Response [4]
Potassium voltage-gated channel subfamily E member 1 (KCNE1) OTZNQUW9 KCNE1_HUMAN Drug Response [4]
Potassium voltage-gated channel subfamily H member 2 (KCNH2) OTZX881H KCNH2_HUMAN Drug Response [4]
Potassium voltage-gated channel subfamily KQT member 1 (KCNQ1) OT8SPJNX KCNQ1_HUMAN Drug Response [4]
Sodium channel protein type 5 subunit alpha (SCN5A) OTGYZWR6 SCN5A_HUMAN Drug Response [4]

References

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