Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM8VUX3)

Drug Name
15-deoxy-Delta(12, 14)-prostaglandin J(2) Drug Info
Synonyms
15d-PGJ2; 15-Deoxy-PGJ2; 15-Deoxy-delta-12,14-prostaglandin J2; 15-deoxy-delta12,14-prostaglandin J2; delta12,14-PGJ 2; UNII-ALI977775J; 87893-55-8; CHEMBL482477; CHEBI:34159; (5Z,12E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid; ALI977775J; delta-12,14-15-Deoxy-PGJ2; 15-Deoxy-delta12,14-prostaglandin; 15-deoxy-Delta(12,14)-prostaglandin J2; Prostaglandin J2, 15-Deoxy-Delta12,14; 15-Deoxy-delta 12, 14-Prostaglandin J2
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
5311211
ChEBI ID
CHEBI:34159
CAS Number
CAS 87893-55-8
TTD Drug ID
DM8VUX3

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Peroxisome proliferator-activated receptor gamma (PPAR-gamma)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [2]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [10]
Lobeglitazone DMHY3IP Type-2 diabetes 5A11 Approved [11]
Rosiglitazone XR DMT45MU Type-2 diabetes 5A11 Approved [12]
Thiazolidinedione DMC1NBW Alzheimer disease 8A20 Approved [10]
Glitazone DMDN4A1 N. A. N. A. Phase 4 [13]
MURAGLITAZAR DMG3NFZ N. A. N. A. Phase 3 [14]
Rivoglitazone DMBY31K Ocular inflammation 9C61.24 Phase 3 [15]
Balaglitazone DMXBHR6 Type-1 diabetes 5A10 Phase 3 [16]
Ragaglitazar DMFSHEM Type-1 diabetes 5A10 Phase 3 [17]
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Drug(s) Affected By Prostaglandin G/H synthase 2 (PTGS2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Eicosapentaenoic acid/docosa-hexaenoic acid DMMUCG4 Hypertriglyceridemia 5C80.1 Approved [18]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [19]
Gamolenic acid DMQN30Z Allergy 4A80-4A85 Approved [20]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [21]
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [22]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [23]
Ibandronate DM0QZBN Hypercalcaemia 5B91.0 Approved [24]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [25]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [26]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [27]
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Drug(s) Affected By Retinoic acid receptor beta (RARB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [28]
Quercetin DM3NC4M Obesity 5B81 Approved [29]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [30]
Panobinostat DM58WKG Chronic graft versus host disease Approved [31]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [32]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [33]
Ethanol DMDRQZU Chronic pain MG30 Approved [34]
Folic Acid DMEMBJC Colorectal carcinoma Approved [35]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [36]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [28]
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Drug(s) Affected By Glial fibrillary acidic protein (GFAP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Penicillin V DMKVOYF Acute otitis media AB00 Approved [37]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [38]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [39]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [40]
Testosterone DM7HUNW Hot flushes GA30 Approved [41]
Haloperidol DM96SE0 Delirium Approved [42]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [33]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [43]
Ethanol DMDRQZU Chronic pain MG30 Approved [44]
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Drug(s) Affected By Retinoic acid receptor RXR-alpha (RXRA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Bexarotene DMOBIKY Cutaneous T-cell lymphoma 2B01 Approved [45]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [46]
Selenium DM25CGV N. A. N. A. Approved [47]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [48]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [49]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [50]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [51]
Acitretin DM8BKU9 Psoriasis vulgaris EA90 Approved [52]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [53]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [54]
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Drug(s) Affected By Choriogonadotropin subunit beta 3 (CGB3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [55]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [56]
Testosterone enanthate DMB6871 N. A. N. A. Approved [57]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [33]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [7]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [58]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [7]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [59]
Bezafibrate DMZDCS0 Hypercholesterolaemia 5C80.0 Approved [60]
Testosterone DM7HUNW Hot flushes GA30 Approved [61]
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Drug(s) Affected By Tumor necrosis factor receptor superfamily member 6 (FAS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [28]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [62]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [63]
Methotrexate DM2TEOL Anterior urethra cancer Approved [64]
Epinephrine DM3KJBC Acute asthma CA23 Approved [65]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [67]
Fructose DM43AN2 Vomiting MD90 Approved [68]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [28]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [69]
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Drug(s) Affected By Cytochrome P450 4A11 (CYP4A11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [70]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [71]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [71]
Methotrexate DM2TEOL Anterior urethra cancer Approved [72]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [48]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [73]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [73]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [71]
Etodolac DM6WJO9 Osteoarthritis FA00-FA05 Approved [71]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [71]
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Drug(s) Affected By Proline dehydrogenase 1, mitochondrial (PRODH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [74]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [75]
Panobinostat DM58WKG Chronic graft versus host disease Approved [31]
Testosterone DM7HUNW Hot flushes GA30 Approved [76]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [76]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [77]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [78]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [74]
Menthol DMG2KW7 Back pain ME84.Z Approved [79]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [80]
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Drug(s) Affected By Histone deacetylase 3 (HDAC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [81]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [82]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [33]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [43]
Melatonin DMKWFBT Depression 6A70-6A7Z Approved [83]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [85]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [86]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [87]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [88]
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Drug(s) Affected By CASP8 and FADD-like apoptosis regulator (CFLAR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [28]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [89]
Methotrexate DM2TEOL Anterior urethra cancer Approved [90]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [91]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [92]
Quercetin DM3NC4M Obesity 5B81 Approved [93]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [94]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [95]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [96]
Ethacrynic acid DM60QMR Edema MG29 Approved [97]
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Drug(s) Affected By Toll-like receptor 2 (TLR2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [98]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [99]
Quercetin DM3NC4M Obesity 5B81 Approved [100]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [75]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [98]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [101]
Tibolone DM78XFG Anabolic metabolism 5C50-5C8Z Approved [102]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [77]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [99]
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Drug(s) Affected By Transforming growth factor beta-1 proprotein (TGFB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [104]
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [37]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [105]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [106]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [107]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [108]
Prednisone DM2HG4X Acute asthma CA23 Approved [109]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [110]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [111]
Methotrexate DM2TEOL Anterior urethra cancer Approved [72]
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Drug(s) Affected By Thyroglobulin (TG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [112]
Propylthiouracil DM6D7N8 Hyperthyroidism 5A02 Approved [113]
Nevirapine DM6HX9B Human immunodeficiency virus infection 1C62 Approved [114]
Testosterone DM7HUNW Hot flushes GA30 Approved [76]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [76]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [115]
Efavirenz DMC0GSJ Human immunodeficiency virus infection 1C62 Approved [114]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [33]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [116]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [59]
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Drug(s) Affected By Tumor necrosis factor (TNF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [117]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [118]
Fructose DM43AN2 Vomiting MD90 Approved [37]
Ketoprofen DMRKXPT Bursitis Approved [37]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [119]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [120]
Baclofen DM0QV1J Multiple sclerosis 8A40 Approved [121]
Gefitinib DM15F0X Colon adenocarcinoma Approved [122]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [123]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [124]
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Drug(s) Affected By Interferon gamma (IFNG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [125]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [126]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [127]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [128]
Methotrexate DM2TEOL Anterior urethra cancer Approved [72]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [129]
Quercetin DM3NC4M Obesity 5B81 Approved [130]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [131]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [132]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [133]
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Drug(s) Affected By Interleukin-1 beta (IL1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [134]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [135]
Gefitinib DM15F0X Colon adenocarcinoma Approved [136]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [26]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [137]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [26]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [138]
Selenium DM25CGV N. A. N. A. Approved [139]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [140]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [141]
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Drug(s) Affected By Fibronectin (FN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [142]
Methotrexate DM2TEOL Anterior urethra cancer Approved [72]
Quercetin DM3NC4M Obesity 5B81 Approved [29]
Aripiprazole DM3NUMH Bipolar I disorder Approved [143]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [8]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [144]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [145]
Ethacrynic acid DM60QMR Edema MG29 Approved [146]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [147]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [148]
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Drug(s) Affected By Interstitial collagenase (MMP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [149]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Etretinate DM2CZFA Keratosis ED56 Approved [151]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [152]
Methotrexate DM2TEOL Anterior urethra cancer Approved [153]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [154]
Quercetin DM3NC4M Obesity 5B81 Approved [155]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [156]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [157]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [158]
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Drug(s) Affected By Glucocorticoid receptor (NR3C1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [159]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [25]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [46]
Selenium DM25CGV N. A. N. A. Approved [160]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [161]
Methotrexate DM2TEOL Anterior urethra cancer Approved [72]
Quercetin DM3NC4M Obesity 5B81 Approved [162]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [163]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [95]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [164]
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Drug(s) Affected By Superoxide dismutase , mitochondrial (SOD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [165]
Selenium DM25CGV N. A. N. A. Approved [139]
Methotrexate DM2TEOL Anterior urethra cancer Approved [98]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [166]
Epinephrine DM3KJBC Acute asthma CA23 Approved [167]
Quercetin DM3NC4M Obesity 5B81 Approved [168]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [169]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [48]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [170]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [171]
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Drug(s) Affected By Heat shock protein beta-1 (HSPB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [172]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [173]
Selenium DM25CGV N. A. N. A. Approved [160]
Methotrexate DM2TEOL Anterior urethra cancer Approved [174]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [95]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [175]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [176]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [177]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [178]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [179]
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Drug(s) Affected By Intercellular adhesion molecule 1 (ICAM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [180]
Dicloxacillin DM8EU0Z Bacterial infection 1A00-1C4Z Approved [180]
Ergonovine DM0VEC1 Postpartum haemorrhage JA43 Approved [37]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [181]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [182]
Mizolastine DM1FDN8 Allergic rhinitis CA08.0 Approved [183]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [184]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [185]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [186]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [187]
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Drug(s) Affected By Transcription factor Sp1 (SP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fructose DM43AN2 Vomiting MD90 Approved [37]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [188]
Quercetin DM3NC4M Obesity 5B81 Approved [189]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [8]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [190]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [112]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [191]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [188]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [192]
Plicamycin DM7C8YV Hypercalcaemia 5B91.0 Approved [193]
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Drug(s) Affected By Monocyte differentiation antigen CD14 (CD14)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [194]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [48]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [163]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [195]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [196]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [197]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [198]
Testosterone DM7HUNW Hot flushes GA30 Approved [76]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [199]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [77]
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Drug(s) Affected By Heme oxygenase 1 (HMOX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [200]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [201]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [202]
Verapamil DMA7PEW Angina pectoris BA40 Approved [203]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [135]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [165]
Selenium DM25CGV N. A. N. A. Approved [204]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [187]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [205]
Methotrexate DM2TEOL Anterior urethra cancer Approved [153]
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Drug(s) Affected By Poly polymerase 1 (PARP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [206]
Gefitinib DM15F0X Colon adenocarcinoma Approved [207]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [208]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [63]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [209]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [210]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [209]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [211]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [212]
Methotrexate DM2TEOL Anterior urethra cancer Approved [213]
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Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [214]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [215]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [216]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [202]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [217]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [135]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [26]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [137]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [218]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [26]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcriptional activator Myb (MYB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [219]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [46]
Methotrexate DM2TEOL Anterior urethra cancer Approved [220]
Quercetin DM3NC4M Obesity 5B81 Approved [221]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [222]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [223]
Estrone DM5T6US Acne vulgaris ED80 Approved [219]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [224]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [225]
Testosterone DM7HUNW Hot flushes GA30 Approved [76]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Hepatocyte growth factor (HGF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [226]
Quercetin DM3NC4M Obesity 5B81 Approved [227]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [169]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [228]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [228]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [158]
Nevirapine DM6HX9B Human immunodeficiency virus infection 1C62 Approved [229]
Etodolac DM6WJO9 Osteoarthritis FA00-FA05 Approved [230]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [231]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [232]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G2/mitotic-specific cyclin-B1 (CCNB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [149]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [233]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [234]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [46]
Selenium DM25CGV N. A. N. A. Approved [235]
Etretinate DM2CZFA Keratosis ED56 Approved [236]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [210]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [237]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [238]
Methotrexate DM2TEOL Anterior urethra cancer Approved [239]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fatty acid-binding protein, adipocyte (FABP4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [169]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [240]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [241]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [164]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [169]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [77]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [33]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [242]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [243]
Capsaicin DMGMF6V Back pain ME84.Z Approved [244]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclic AMP-responsive element-binding protein 1 (CREB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aspirin DM672AH Acute coronary syndrome BA41 Approved [245]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [246]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [247]
Selenium DM25CGV N. A. N. A. Approved [160]
Methotrexate DM2TEOL Anterior urethra cancer Approved [248]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [8]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [249]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [249]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [250]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [251]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Platelet glycoprotein 4 (CD36)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [252]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [253]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [75]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [254]
Tolcapone DM8MNVO Parkinson disease 8A00.0 Approved [255]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [256]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [257]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [258]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [259]
Asasantin DMCZIHT Cerebrovascular ischaemia 8B1Z Approved [260]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP synthase-coupling factor 6, mitochondrial (ATP5PF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [160]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [3]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [261]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [257]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [33]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [43]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [262]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [263]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [264]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nuclear factor NF-kappa-B p105 subunit (NFKB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [200]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [265]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [194]
Gefitinib DM15F0X Colon adenocarcinoma Approved [266]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [226]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [267]
Methotrexate DM2TEOL Anterior urethra cancer Approved [268]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [269]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [270]
Quercetin DM3NC4M Obesity 5B81 Approved [93]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-A2 (CCNA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [271]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [233]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [272]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [62]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [273]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [274]
Methotrexate DM2TEOL Anterior urethra cancer Approved [239]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [275]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [276]
Quercetin DM3NC4M Obesity 5B81 Approved [162]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Thromboxane A2 receptor (TBXA2R)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aspirin DM672AH Acute coronary syndrome BA41 Approved [277]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [278]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [33]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [278]
Arsenic DMTL2Y1 N. A. N. A. Approved [279]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [86]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [179]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [280]
acetaldehyde DMJFKG4 Discovery agent N.A. Investigative [281]
Sulforaphane DMQY3L0 Skin disease EA00-EM0Z Investigative [282]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G1/S-specific cyclin-E1 (CCNE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [206]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [283]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [273]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [210]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [274]
Quercetin DM3NC4M Obesity 5B81 Approved [162]
Fluoxetine DM3PD2C Bipolar depression Approved [284]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [285]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [286]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [287]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase 2 (CDK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [149]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [233]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [283]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [288]
Selenium DM25CGV N. A. N. A. Approved [235]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [210]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [289]
Methotrexate DM2TEOL Anterior urethra cancer Approved [90]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [290]
Quercetin DM3NC4M Obesity 5B81 Approved [221]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By NF-kappa-B inhibitor alpha (NFKBIA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fructose DM43AN2 Vomiting MD90 Approved [37]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [291]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [134]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [135]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [165]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [292]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [293]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [294]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [295]
Quercetin DM3NC4M Obesity 5B81 Approved [162]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [296]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [297]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [246]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [120]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [298]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [299]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [300]
Gefitinib DM15F0X Colon adenocarcinoma Approved [301]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [302]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [303]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [304]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [297]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [305]
Paclitaxel DMLB81S Breast carcinoma Approved [306]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [307]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [296]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [37]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [134]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [120]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [298]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G1/S-specific cyclin-D2 (CCND2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [308]
Selenium DM25CGV N. A. N. A. Approved [235]
Methotrexate DM2TEOL Anterior urethra cancer Approved [153]
Quercetin DM3NC4M Obesity 5B81 Approved [221]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [222]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [309]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [310]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [311]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [312]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [313]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G1/S-specific cyclin-D3 (CCND3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [149]
Gefitinib DM15F0X Colon adenocarcinoma Approved [314]
Quercetin DM3NC4M Obesity 5B81 Approved [221]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [315]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [9]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [309]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [316]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [317]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [265]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [177]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Peroxisome proliferator-activated receptor gamma (PPARG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [21]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [318]
Quercetin DM3NC4M Obesity 5B81 Approved [319]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [240]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [95]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [320]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [321]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [67]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [322]
Stavudine DM6DEK9 Human immunodeficiency virus infection 1C62 Approved [323]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [310]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [324]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [234]
Gefitinib DM15F0X Colon adenocarcinoma Approved [325]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [326]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [62]
Etretinate DM2CZFA Keratosis ED56 Approved [236]
Prednisone DM2HG4X Acute asthma CA23 Approved [327]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [210]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [328]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Leptin (LEP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [329]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [124]
Ramipril DM2R68E Acute heart failure BD10-BD13 Approved [330]
Quercetin DM3NC4M Obesity 5B81 Approved [331]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [332]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [329]
Stavudine DM6DEK9 Human immunodeficiency virus infection 1C62 Approved [329]
Nevirapine DM6HX9B Human immunodeficiency virus infection 1C62 Approved [229]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [56]
Amlodipine DMBDAZV Angina pectoris BA40 Approved [333]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [334]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [335]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [336]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [337]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [338]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [339]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [340]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [341]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [342]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [291]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase inhibitor 1B (CDKN1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [343]
Gefitinib DM15F0X Colon adenocarcinoma Approved [314]
Prednisone DM2HG4X Acute asthma CA23 Approved [327]
Methotrexate DM2TEOL Anterior urethra cancer Approved [344]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [345]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [346]
Quercetin DM3NC4M Obesity 5B81 Approved [347]
Fluoxetine DM3PD2C Bipolar depression Approved [284]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [348]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [349]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glutamate--cysteine ligase catalytic subunit (GCLC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [350]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [165]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [351]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [352]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [353]
Quercetin DM3NC4M Obesity 5B81 Approved [354]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [163]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [75]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [355]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [356]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Heat shock factor protein 1 (HSF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [357]
SPI-1005 DM6XFHS Reperfusion injury ND56.Z Approved [358]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [358]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [359]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [360]
Ceftazidime DM41GRA Bacteremia 1A73 Approved [358]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [75]
Chlorpheniramine DM5URA2 Allergic rhinitis CA08.0 Approved [358]
Ethacrynic acid DM60QMR Edema MG29 Approved [358]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [358]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Peroxisome proliferator-activated receptor delta (PPARD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [350]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [361]
Methotrexate DM2TEOL Anterior urethra cancer Approved [72]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [112]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [362]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [363]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [364]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [365]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [77]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [259]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor p65 (RELA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [134]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [366]
Selenium DM25CGV N. A. N. A. Approved [160]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [367]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [270]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [295]
Quercetin DM3NC4M Obesity 5B81 Approved [162]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [368]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [55]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [369]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone acetyltransferase p300 (EP300)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [370]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [371]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [317]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [177]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [372]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [43]
Menthol DMG2KW7 Back pain ME84.Z Approved [79]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [373]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [374]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Baculoviral IAP repeat-containing protein 3 (BIRC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paclitaxel DMLB81S Breast carcinoma Approved [375]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [291]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [376]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [63]
Methotrexate DM2TEOL Anterior urethra cancer Approved [153]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [48]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [112]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [69]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [377]
Trovafloxacin DM6AN32 Acute gonococcal cervicitis Approved [378]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Baculoviral IAP repeat-containing protein 2 (BIRC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paclitaxel DMLB81S Breast carcinoma Approved [375]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [291]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [92]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [379]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [380]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [381]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [382]
Trovafloxacin DM6AN32 Acute gonococcal cervicitis Approved [378]
Etodolac DM6WJO9 Osteoarthritis FA00-FA05 Approved [383]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [384]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone deacetylase 1 (HDAC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [226]
Methotrexate DM2TEOL Anterior urethra cancer Approved [220]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [379]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [385]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [386]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [77]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [259]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [43]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [387]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [388]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Hypoxia-inducible factor 1-alpha (HIF1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [389]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [390]
Prednisone DM2HG4X Acute asthma CA23 Approved [391]
Triamterene DM2HU9I Congestive heart failure BD10 Approved [391]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [392]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [393]
Epinephrine DM3KJBC Acute asthma CA23 Approved [394]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Fluoxetine DM3PD2C Bipolar depression Approved [395]
Romiplostim DM3U7SZ Thrombocytopenia 3B64 Approved [396]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Proprotein convertase subtilisin/kexin type 9 (PCSK9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [162]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [74]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [397]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [77]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [313]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [398]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [399]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [400]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [401]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone deacetylase 2 (HDAC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [402]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [75]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [355]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [403]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [386]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [404]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [43]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [80]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [405]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [46]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP-binding cassette sub-family C member 3 (ABCC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paclitaxel DMLB81S Breast carcinoma Approved [406]
Methotrexate DM2TEOL Anterior urethra cancer Approved [407]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [408]
Calcipotriol DM03CP7 Psoriasis EA90 Approved [409]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [350]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [272]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [46]
Prednisone DM2HG4X Acute asthma CA23 Approved [410]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [353]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [294]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Multidrug resistance-associated protein 1 (ABCC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [411]
Folic Acid DMEMBJC Colorectal carcinoma Approved [412]
Methotrexate DM2TEOL Anterior urethra cancer Approved [413]
Quercetin DM3NC4M Obesity 5B81 Approved [414]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [415]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [416]
Epirubicin DMPDW6T Solid tumour/cancer 2A00-2F9Z Approved [417]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [418]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [419]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [419]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Peroxisome proliferator-activated receptor gamma (PPAR-gamma) TTZMAO3 PPARG_HUMAN Agonist [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
ATP synthase-coupling factor 6, mitochondrial (ATP5PF) OTDAE8FP ATP5J_HUMAN Gene/Protein Processing [3]
ATP-binding cassette sub-family C member 3 (ABCC3) OTC3IJV4 MRP3_HUMAN Regulation of Drug Effects [4]
Baculoviral IAP repeat-containing protein 2 (BIRC2) OTFXFREP BIRC2_HUMAN Gene/Protein Processing [5]
Baculoviral IAP repeat-containing protein 3 (BIRC3) OT3E95KB BIRC3_HUMAN Gene/Protein Processing [5]
CASP8 and FADD-like apoptosis regulator (CFLAR) OTX14BAS CFLAR_HUMAN Gene/Protein Processing [5]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [6]
Choriogonadotropin subunit beta 3 (CGB3) OTVM2SU3 CGB3_HUMAN Gene/Protein Processing [7]
Cyclic AMP-responsive element-binding protein 1 (CREB1) OT1MDLA1 CREB1_HUMAN Post-Translational Modifications [8]
Cyclin-A2 (CCNA2) OTPHHYZJ CCNA2_HUMAN Gene/Protein Processing [9]
Cyclin-dependent kinase 2 (CDK2) OTB5DYYZ CDK2_HUMAN Gene/Protein Processing [9]

References

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