Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMM1LG2)

Drug Name
Dihydroxyacetone Drug Info
Synonyms
1,3-dihydroxyacetone; Dihydroxyacetone; 96-26-4; 1,3-Dihydroxypropan-2-one; Chromelin; 1,3-Dihydroxy-2-propanone; glycerone; Triulose; Viticolor; Soleal; Oxatone; Dihyxal; Oxantin; Otan; 2-Propanone, 1,3-dihydroxy-; 1,3-Dihydroxypropanone; 1,3-Dihydroxydimethyl ketone; NSC-24343; Ketochromin; Bis(hydroxymethyl) ketone; UNII-O10DDW6JOO; dihydroxy-acetone; 2-Propanone, 1,3-dihydroxy; BRN 1740268; CCRIS 4899; AI3-24477; Dihydroxyacetone [USP]; EINECS 202-494-5; O10DDW6JOO; 1,2-Dihydroxy-2-propanone; CHEBI:16016; RXKJFZQQPQGTFL-UHFFFAOYSA-N
Indication
Disease Entry ICD 11 Status REF
Sunburn EJ40 Approved [1]
Cross-matching ID
PubChem CID
670
ChEBI ID
CHEMBL16016
CAS Number
CAS 96-26-4
TTD Drug ID
DMM1LG2
INTEDE Drug ID
DR2086

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DME
DOT
Drug Status:
Investigative Drug(s)
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Metabolized By Triokinase/FMN cyclase (TKFC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
D-glyceraldehyde DMAYPLE N. A. N. A. Investigative [2]
Drug(s) Affected By C-C motif chemokine 21 (CCL21)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [5]
Methotrexate DM2TEOL Anterior urethra cancer Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [7]
Arsenic DMTL2Y1 N. A. N. A. Approved [8]
Capecitabine DMTS85L Adenocarcinoma 2D40 Approved [9]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [10]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [11]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [12]
USNIC ACID DMGOURX Discovery agent N.A. Investigative [13]
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Drug(s) Affected By Serine/threonine-protein kinase Chk2 (CHEK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [14]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [15]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [16]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [17]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [18]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [19]
Testosterone DM7HUNW Hot flushes GA30 Approved [20]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [20]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [7]
Capsaicin DMGMF6V Back pain ME84.Z Approved [21]
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Drug(s) Affected By Alpha-crystallin B chain (CRYAB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [22]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [23]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [24]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [25]
Testosterone DM7HUNW Hot flushes GA30 Approved [20]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [20]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [26]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [27]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [28]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [29]
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Drug(s) Affected By Heat shock protein beta-1 (HSPB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [30]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [22]
Selenium DM25CGV N. A. N. A. Approved [31]
Methotrexate DM2TEOL Anterior urethra cancer Approved [32]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [33]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [34]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [35]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [36]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [38]
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Drug(s) Affected By Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [39]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [40]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [41]
Quercetin DM3NC4M Obesity 5B81 Approved [42]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [43]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [44]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [45]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [46]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [47]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [48]
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Drug(s) Affected By Stromelysin-2 (MMP10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [49]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [50]
Methotrexate DM2TEOL Anterior urethra cancer Approved [51]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [52]
Quercetin DM3NC4M Obesity 5B81 Approved [42]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [51]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [53]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [36]
Haloperidol DM96SE0 Delirium Approved [54]
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Drug(s) Affected By Poly polymerase 1 (PARP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [50]
Gefitinib DM15F0X Colon adenocarcinoma Approved [55]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [56]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [57]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [58]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [59]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [58]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [60]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [61]
Methotrexate DM2TEOL Anterior urethra cancer Approved [62]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By C-C motif chemokine 3 (CCL3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [63]
Methotrexate DM2TEOL Anterior urethra cancer Approved [6]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [23]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [44]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [64]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [65]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [66]
Betamethasone DMAHJEF Acute adrenal insufficiency Approved [67]
Emetine DMCT2YF Hepatitis virus infection 1E50-1E51 Approved [67]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [63]
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Drug(s) Affected By 60 kDa heat shock protein, mitochondrial (HSPD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [40]
Etretinate DM2CZFA Keratosis ED56 Approved [68]
Methotrexate DM2TEOL Anterior urethra cancer Approved [69]
Quercetin DM3NC4M Obesity 5B81 Approved [70]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [23]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [71]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [47]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [72]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [34]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [73]
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Drug(s) Affected By C-C motif chemokine 4 (CCL4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [23]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [44]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [74]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [66]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [75]
Betamethasone DMAHJEF Acute adrenal insufficiency Approved [67]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [26]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [7]
Emetine DMCT2YF Hepatitis virus infection 1E50-1E51 Approved [67]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [76]
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Drug(s) Affected By Histone H2AX (H2AX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [77]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [78]
Selenium DM25CGV N. A. N. A. Approved [31]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [79]
Etretinate DM2CZFA Keratosis ED56 Approved [80]
Methotrexate DM2TEOL Anterior urethra cancer Approved [81]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [82]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [83]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [84]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
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Drug(s) Affected By Heat shock 70 kDa protein 6 (HSPA6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [86]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [39]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [87]
Quercetin DM3NC4M Obesity 5B81 Approved [88]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [89]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [44]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [91]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [92]
Leflunomide DMR8ONJ Arthritis FA20 Approved [93]
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Drug(s) Affected By Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [94]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [95]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [96]
Methotrexate DM2TEOL Anterior urethra cancer Approved [69]
Quercetin DM3NC4M Obesity 5B81 Approved [97]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [98]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [34]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [99]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [19]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [100]
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Drug(s) Affected By General transcription and DNA repair factor IIH helicase subunit XPB (ERCC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [101]
Menthol DMG2KW7 Back pain ME84.Z Approved [102]
Arsenic DMTL2Y1 N. A. N. A. Approved [103]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [104]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [11]
Bortezomib DMNO38U Leukemia Approved [105]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [106]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [106]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [31]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [107]
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Drug(s) Affected By Nuclear factor NF-kappa-B p105 subunit (NFKB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [108]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [109]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [39]
Gefitinib DM15F0X Colon adenocarcinoma Approved [110]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [111]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [112]
Methotrexate DM2TEOL Anterior urethra cancer Approved [113]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [114]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [115]
Quercetin DM3NC4M Obesity 5B81 Approved [97]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-C (CCNC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [116]
Testosterone DM7HUNW Hot flushes GA30 Approved [117]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [118]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [7]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [119]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [120]
Arsenic DMTL2Y1 N. A. N. A. Approved [121]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [122]
Inecalcitol oral DMU5SZP Acute myeloid leukaemia 2A60 Phase 2 [123]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [124]
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Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [125]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [126]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [127]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [128]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [129]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [130]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [131]
Gefitinib DM15F0X Colon adenocarcinoma Approved [132]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [133]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [134]
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Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [135]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [126]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [136]
Paclitaxel DMLB81S Breast carcinoma Approved [137]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [138]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [125]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [94]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [139]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [128]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [129]
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Drug(s) Affected By DNA damage-inducible transcript 3 protein (DDIT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [86]
Triacetin DM0AEPG Onychomycosis EE12.1 Approved [140]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [39]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [141]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [142]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [87]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [143]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [144]
Methotrexate DM2TEOL Anterior urethra cancer Approved [145]
Quercetin DM3NC4M Obesity 5B81 Approved [42]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [146]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [147]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [148]
Gefitinib DM15F0X Colon adenocarcinoma Approved [149]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [150]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [87]
Etretinate DM2CZFA Keratosis ED56 Approved [151]
Prednisone DM2HG4X Acute asthma CA23 Approved [152]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [59]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [153]
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Drug(s) Affected By Collagenase 3 (MMP13)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [154]
Clindamycin DM15HL8 Acne vulgaris ED80 Approved [155]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [154]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [52]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [156]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [157]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [158]
Doxycycline DM7ICNU Acne vulgaris ED80 Approved [155]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [159]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [160]
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Drug(s) Affected By Tumor necrosis factor ligand superfamily member 6 (FASLG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [161]
Gefitinib DM15F0X Colon adenocarcinoma Approved [162]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [163]
Epinephrine DM3KJBC Acute asthma CA23 Approved [164]
Quercetin DM3NC4M Obesity 5B81 Approved [165]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [23]
Fructose DM43AN2 Vomiting MD90 Approved [166]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [167]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [168]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [169]
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Drug(s) Affected By Tumor necrosis factor ligand superfamily member 10 (TNFSF10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [141]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [170]
Selenium DM25CGV N. A. N. A. Approved [31]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [171]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [172]
Methotrexate DM2TEOL Anterior urethra cancer Approved [173]
Quercetin DM3NC4M Obesity 5B81 Approved [42]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [23]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [174]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [175]
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Drug(s) Affected By Heat shock-related 70 kDa protein 2 (HSPA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [50]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [176]
Quercetin DM3NC4M Obesity 5B81 Approved [88]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [89]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [44]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [177]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [178]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [179]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [49]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [180]
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Drug(s) Affected By 10 kDa heat shock protein, mitochondrial (HSPE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [176]
Quercetin DM3NC4M Obesity 5B81 Approved [181]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [71]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [92]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [71]
Leflunomide DMR8ONJ Arthritis FA20 Approved [93]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [182]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [28]
Ethanol DMDRQZU Chronic pain MG30 Approved [183]
Folic Acid DMEMBJC Colorectal carcinoma Approved [184]
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Drug(s) Affected By Mucin-5AC (MUC5AC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [170]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [185]
Selenium DM25CGV N. A. N. A. Approved [186]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [170]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [187]
Capsaicin DMGMF6V Back pain ME84.Z Approved [188]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [170]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [170]
Bleomycin DMNER5S Cervical cancer 2C77.0 Approved [189]
Arsenic DMTL2Y1 N. A. N. A. Approved [190]
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Drug(s) Affected By Transcription factor E2F1 (E2F1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [191]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [50]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [192]
Gefitinib DM15F0X Colon adenocarcinoma Approved [193]
Selenium DM25CGV N. A. N. A. Approved [31]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [153]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [194]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [52]
Quercetin DM3NC4M Obesity 5B81 Approved [42]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [89]
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Drug(s) Affected By Flavin-containing monooxygenase 1 (FMO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [111]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [23]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [44]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [195]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [26]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [7]
Atazanavir DMSYRBX Human immunodeficiency virus infection 1C62 Approved [195]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [196]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [197]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [198]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine-protein kinase ATM (ATM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [199]
Paromomycin DM1AGXN Amoebiasis 1A36 Approved [200]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [201]
Etretinate DM2CZFA Keratosis ED56 Approved [151]
Quercetin DM3NC4M Obesity 5B81 Approved [202]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Remdesivir DMBFZ6L Coronavirus Disease 2019 (COVID-19) 1D6Y Approved [203]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [34]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [204]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [205]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DnaJ homolog subfamily B member 4 (DNAJB4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [86]
Selenium DM25CGV N. A. N. A. Approved [31]
Quercetin DM3NC4M Obesity 5B81 Approved [42]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [23]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [206]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [34]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [207]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [208]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [209]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [86]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Triokinase/FMN cyclase (TKFC) Main DME DEX9ZJQ TKFC_HUMAN Substrate [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
10 kDa heat shock protein, mitochondrial (HSPE1) OT7JSZLB CH10_HUMAN Gene/Protein Processing [3]
60 kDa heat shock protein, mitochondrial (HSPD1) OTTO1Y11 CH60_HUMAN Gene/Protein Processing [3]
Alpha-crystallin B chain (CRYAB) OTY4JGYU CRYAB_HUMAN Gene/Protein Processing [3]
C-C motif chemokine 21 (CCL21) OT7DOXEM CCL21_HUMAN Gene/Protein Processing [3]
C-C motif chemokine 3 (CCL3) OTW2H3ND CCL3_HUMAN Gene/Protein Processing [3]
C-C motif chemokine 4 (CCL4) OT6B8P25 CCL4_HUMAN Gene/Protein Processing [3]
Collagenase 3 (MMP13) OTY8BZIE MMP13_HUMAN Protein Interaction/Cellular Processes [4]
Cyclin-C (CCNC) OTMVK4K4 CCNC_HUMAN Gene/Protein Processing [3]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Gene/Protein Processing [3]
DNA damage-inducible transcript 3 protein (DDIT3) OTI8YKKE DDIT3_HUMAN Gene/Protein Processing [3]

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120 Apoptosis induced by piroxicam plus cisplatin combined treatment is triggered by p21 in mesothelioma. PLoS One. 2011;6(8):e23569.
121 Arsenic-induced cell proliferation is associated with enhanced ROS generation, Erk signaling and CyclinA expression. Toxicol Lett. 2010 Oct 5;198(2):263-71. doi: 10.1016/j.toxlet.2010.07.006. Epub 2010 Jul 21.
122 Cellular response to 5-fluorouracil (5-FU) in 5-FU-resistant colon cancer cell lines during treatment and recovery. Mol Cancer. 2006 May 18;5:20. doi: 10.1186/1476-4598-5-20.
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