General Information of Drug (ID: DMS9503)

Drug Name
Benzylpenicillin Drug Info
Synonyms
penicillin g; Benzylpenicillinic acid; Free penicillin II; Pencillin G; 61-33-6; Benzylpenicillin G; Bencilpenicilina; Benzylpenicillinum; Benzyl penicillin; Free penicillin G; Dropcillin; Pharmacillin; Gelacillin; Liquacillin; Benzopenicillin; Cilopen; Pradupen; Benzylpenicilline; Specilline G; Cilloral; Cosmopen; Ursopen; Galofak; Free benzylpenicillin; Compocillin G; Phenylacetamidopenicillanic acid; 6-(2-Phenylacetamido)penicillanic acid; Pfizerpen; Benzyl-6-aminopenicillinic acid
Indication
Disease Entry ICD 11 Status REF
Actinomycosis Approved [1]
Acute otitis media AB00 Approved [2]
Anthrax 1B97 Approved [3]
Bacterial endocarditis Approved [4]
Botulism 1A11 Approved [5]
Cervicofacial actinomycosis Approved [6]
Congenital syphilis Approved [7]
Cutaneous anthrax Approved [8]
Erysipelas Approved [9]
Erysipelothrix rhusiopathiae infectious disease Approved [10]
Gastrointestinal anthrax Approved [11]
Gonococcal infection of joint Approved [12]
Inhalational anthrax Approved [3]
Late latent syphilis Approved [13]
Latent syphilis Approved [14]
Latent yaws Approved [15]
Listeria meningitis Approved [16]
Lung abscess Approved [17]
Meningococcal meningitis Approved [18]
Meningococcemia Approved [19]
Neonatal sepsis Approved [20]
Neurosyphilis Approved [21]
Pasteurella multocida infectious disease Approved [22]
Pasteurellosis Approved [23]
Pneumococcal meningitis Approved [16]
Psoriasis EA90 Approved [24]
Rat-bite fever Approved [25]
Respiratory tract infection CA45 Approved [26]
Staphylococcus aureus infection Approved [27]
Streptococcal pneumonia Approved [28]
Streptococcal toxic-shock syndrome Approved [29]
Streptococcus infection 1B53 Approved [30]
Syphilis Approved [31]
Tertiary lesion of yaws Approved [32]
Yaws Approved [33]
Bejel Investigative [34]
Latent early syphilis Investigative [35]
Secondary syphilis Investigative [36]
Tertiary syphilis Investigative [37]
Tetanus 1C13 Investigative [38]
Cross-matching ID
PubChem CID
5904
ChEBI ID
CHEBI:18208
CAS Number
CAS 61-33-6
TTD Drug ID
DMS9503
VARIDT Drug ID
DR00488
INTEDE Drug ID
DR2164

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Discontinued Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aztreonam DMDNJHG Bacterial infection 1A00-1C4Z Approved [59]
Cefmetazole DM42W1B Bacterial infection 1A00-1C4Z Approved [60]
Cefotiam DMF5HU6 Respiratory tract infection CA45 Approved [61]
Latamoxef DMANL0D Bacterial infection 1A00-1C4Z Approved [60]
Mezlocillin DMY5JEP Acute gonococcal cervicitis Approved [62]
Moxalactam Disodium DMYKUNR Bacterial infection 1A00-1C4Z Approved [63]
Cefmenoxime DMPLY7B Bacterial infection 1A00-1C4Z Approved [64]
LYS228 DM23Y6K Urinary tract infection GC08 Phase 2 [65]
Cephalosporin C DMYW3ZG Discovery agent N.A. Investigative [66]
PCNOTAXIME GROUP DMGS6YH Discovery agent N.A. Investigative [67]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [68]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [43]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [69]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [70]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [69]
Pravastatin DM6A0X7 Adult acute monocytic leukemia Approved [71]
Mycophenolate mofetil DMPQAGE Hepatosplenic T-cell lymphoma Approved [72]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [73]
Cerivastatin DMXCM7H Hyperlipidaemia 5C80 Approved [74]
PITAVASTATIN CALCIUM DM1UJO0 Dyslipidemia 5C80-5C81 Approved [71]
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Drug(s) Transported By Peptide transporter 1 (SLC15A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [75]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [76]
Ampicillin DMHWE7P Acute epiglottitis Approved [77]
Losartan DM72JXH Diabetic kidney disease GB61.Z Approved [78]
Enalapril DMNFUZR Congestive heart failure BD10 Approved [79]
Cefazolin DMPDYFR Bacteremia 1A73 Approved [80]
Ceftriaxone DMCEW64 Acute gonococcal cervicitis Approved [81]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [76]
Cefadroxil DMMC345 Bacterial infection 1A00-1C4Z Approved [78]
Irbesartan DMTP1DC Diabetic kidney disease GB61.Z Approved [78]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [82]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [83]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [84]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [85]
Pravastatin DM6A0X7 Adult acute monocytic leukemia Approved [45]
L-Tryptophan DMIBH7M Depression 6A70-6A7Z Approved [86]
Mercaptopurine DMTM2IK Acute lymphoblastic leukaemia 2A85 Approved [87]
PITAVASTATIN CALCIUM DM1UJO0 Dyslipidemia 5C80-5C81 Approved [88]
Rosuvastatin DMMIQ7G Arteriosclerosis BD40 Approved [89]
Cilostazol DMZMSCT Intermittent claudication BD40.00 Approved [90]
Valsartan DMREUQ6 Chronic heart failure BD1Z Approved [114]
Methotrexate DM2TEOL Anterior urethra cancer Approved [115]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [116]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [85]
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [117]
Cimetidine DMH61ZB Acid-reflux disorder DA22 Approved [117]
Cefdinir DMJ7A0H Bacterial infection 1A00-1C4Z Approved [118]
Cefaclor DMJXDGC Bacterial infection 1A00-1C4Z Approved [118]
Famotidine DMRL3AB Gastric ulcer DA60 Approved [119]
Tetracycline DMZA017 Acne vulgaris ED80 Approved [120]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [91]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [69]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [92]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [93]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [69]
Pravastatin DM6A0X7 Adult acute monocytic leukemia Approved [94]
Mycophenolate mofetil DMPQAGE Hepatosplenic T-cell lymphoma Approved [72]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [74]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [95]
Cerivastatin DMXCM7H Hyperlipidaemia 5C80 Approved [74]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [41]
L-Glutamic Acid DM4PUDW Schizophrenia 6A20 Approved [96]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [97]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [70]
Pravastatin DM6A0X7 Adult acute monocytic leukemia Approved [98]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [99]
Cerivastatin DMXCM7H Hyperlipidaemia 5C80 Approved [100]
PITAVASTATIN CALCIUM DM1UJO0 Dyslipidemia 5C80-5C81 Approved [101]
Digoxin DMQCTIH Arrhythmia BC9Z Approved [102]
Rosuvastatin DMMIQ7G Arteriosclerosis BD40 Approved [103]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [104]
Alprostadil DMWH7NQ Aorta coarctation Approved [104]
Iloprost DMVPZBE Pulmonary arterial hypertension BB01.0 Approved [104]
Estrone sulfate DMVBIZL Atrophic vaginitis GA30.2 Approved [41]
PGF2alpha DM4XAU7 Solid tumour/cancer 2A00-2F9Z Clinical trial [104]
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [41]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [105]
Estrone sulfate DMVBIZL Atrophic vaginitis GA30.2 Approved [106]
Taurocholic Acid DM2LZ8F Type-2 diabetes 5A11 Phase 1/2 [107]
Drug(s) Metabolized By Beta-lactamase (blaB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [108]
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [109]
Ampicillin DMHWE7P Acute epiglottitis Approved [48]
Piperacillin DMTBKF3 Acute gonococcal cervicitis Approved [48]
Cefalotin DMVYSLE Bacteremia 1A73 Approved [48]
Cephaloridine DM4Y95F Gram-positive bacterial infection 1B74-1G40 Withdrawn from market [48]
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [109]
Cefazolin DMPDYFR Bacteremia 1A73 Approved [109]
Meropenem DM62UHC Bacterial infection 1A00-1C4Z Approved [109]
Cefalotin DMVYSLE Bacteremia 1A73 Approved [110]
Cephalosporin DM79XDW Bacterial infection 1A00-1C4Z Approved [51]
Carbapenem DMXZU73 N. A. N. A. Phase 4 [51]
Ampicillin DMHWE7P Acute epiglottitis Approved [111]
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [112]
Ticarcillin DM4ME02 Aspiration pneumonia Approved [112]
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [113]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [47]
Ampicillin DMHWE7P Acute epiglottitis Approved [47]
Cefadroxil DMMC345 Bacterial infection 1A00-1C4Z Approved [47]
Cephalexin DMD5JU8 Acute otitis media AB00 Approved [47]
Carbenicillin DMLEDNK Infection of the upper and lower urinary tract GC08 Approved [47]
Drug(s) Affected By Pirin (PIR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [121]
Quercetin DM3NC4M Obesity 5B81 Approved [122]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [123]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [124]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [125]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [126]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [127]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [127]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [128]
Sulfamethoxazole DMB08GE Acute otitis media AB00 Approved [57]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [129]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [130]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [131]
Testosterone enanthate DMB6871 N. A. N. A. Approved [132]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [133]
Ampicillin DMHWE7P Acute epiglottitis Approved [57]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [134]
Penicillin V DMKVOYF Acute otitis media AB00 Approved [57]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [135]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [136]
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Drug(s) Affected By Interleukin-1 beta (IL1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [137]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [138]
Gefitinib DM15F0X Colon adenocarcinoma Approved [139]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [140]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [141]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [140]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [142]
Selenium DM25CGV N. A. N. A. Approved [143]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [144]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [145]
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Drug(s) Affected By NAD(P)H dehydrogenase 1 (NQO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [127]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [146]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [147]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [141]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [148]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [149]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [150]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [151]
Quercetin DM3NC4M Obesity 5B81 Approved [152]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [153]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [154]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [155]
Dextropropoxyphene DM23HCX Pain MG30-MG3Z Approved [156]
Selenium DM25CGV N. A. N. A. Approved [157]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [158]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [129]
Tacrine DM51FY6 Alzheimer disease 8A20 Approved [159]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [160]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [161]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [162]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [147]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [163]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [164]
Quercetin DM3NC4M Obesity 5B81 Approved [165]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [129]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [124]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [166]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [167]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [130]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [56]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dantrolene DM1D8XY Hyperthermia MG26 Approved [168]
Quercetin DM3NC4M Obesity 5B81 Approved [169]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [123]
Panobinostat DM58WKG Chronic graft versus host disease Approved [170]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [171]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [172]
Testosterone DM7HUNW Hot flushes GA30 Approved [173]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [174]
Folic Acid DMEMBJC Colorectal carcinoma Approved [175]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [176]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Alpha-fetoprotein (AFP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [167]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [177]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [179]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [167]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [180]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [181]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [128]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [182]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [183]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [184]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [185]
Etretinate DM2CZFA Keratosis ED56 Approved [186]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [187]
Methotrexate DM2TEOL Anterior urethra cancer Approved [188]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [189]
Quercetin DM3NC4M Obesity 5B81 Approved [190]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [191]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [192]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [125]
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Drug(s) Affected By Decorin (DCN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [193]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [194]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [195]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [179]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [196]
Testosterone DM7HUNW Hot flushes GA30 Approved [197]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [131]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [198]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [199]
Folic Acid DMEMBJC Colorectal carcinoma Approved [200]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Annexin A8 (ANXA8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [129]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [126]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [199]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [201]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [202]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [203]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [204]
Paclitaxel DMLB81S Breast carcinoma Approved [205]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [206]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [207]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [208]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [209]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [195]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [179]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [210]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [124]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [211]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [212]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [199]
Ethanol DMDRQZU Chronic pain MG30 Approved [213]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [122]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [153]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [179]
Panobinostat DM58WKG Chronic graft versus host disease Approved [170]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [153]
Testosterone enanthate DMB6871 N. A. N. A. Approved [132]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [214]
Folic Acid DMEMBJC Colorectal carcinoma Approved [215]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [216]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [217]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [218]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [219]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [220]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [221]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [222]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [138]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [140]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [141]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [223]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [140]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [224]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [209]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [225]
Methotrexate DM2TEOL Anterior urethra cancer Approved [226]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [227]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [228]
Quercetin DM3NC4M Obesity 5B81 Approved [122]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [229]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [129]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [166]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [230]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [231]
Kanamycin DM2DMPO Bacteremia 1A73 Approved [232]
Methotrexate DM2TEOL Anterior urethra cancer Approved [233]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [234]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [129]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [232]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [125]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [232]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [131]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-18 (IL18)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [137]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [235]
Methotrexate DM2TEOL Anterior urethra cancer Approved [233]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [236]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [237]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [238]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [239]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [240]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [241]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [240]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [242]
Quercetin DM3NC4M Obesity 5B81 Approved [243]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [244]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [245]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [179]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [246]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [247]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [248]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [249]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [250]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Bacterial Penicillin binding protein 1 (Bact pbp) TTTKCMH PBPA_ECOLI; PBPB_ECOLI; PBPC_ECOLI Binder [39]
Bacterial Penicillin binding protein 3 (Bact mrcA) TT85JMW FTSI_ECOLI Binder [40]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Organic anion transporting polypeptide 3A1 (SLCO3A1) DTVNRXW SO3A1_HUMAN Substrate [41]
Organic anion transporting polypeptide 4A1 (SLCO4A1) DT8H2IC SO4A1_HUMAN Substrate [41]
Peptide transporter 1 (SLC15A1) DT9G7XN S15A1_HUMAN Substrate [42]
Organic anion transporting polypeptide 2B1 (SLCO2B1) DTPFTEQ SO2B1_HUMAN Substrate [41]
Organic anion transporting polypeptide 1B1 (SLCO1B1) DT3D8F0 SO1B1_HUMAN Substrate [43]
Organic anion transporting polypeptide 1B3 (SLCO1B3) DT9C1TS SO1B3_HUMAN Substrate [44]
Organic anion transporter 3 (SLC22A8) DTVP67E S22A8_HUMAN Substrate [45]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Beta-lactamase (blaB) DEV0KWQ Q8KT52_9BACT Substrate [46]
N-acylhomoserine lactone acylase (lacA) DEIU0XN A0A0A1VBK6_9BURK Substrate [47]
Beta-lactamase (blaB) DET9I1W BLAC_BACUN Substrate [48]
Beta-lactamase (blaB) DENJ2SQ BLAB_BACFG Substrate [46]
Beta-lactamase (blaB) DE37FJH C6JIU1_FUSVA Substrate [46]
Beta-lactamase (blaB) DEAILCM A0A246EJV2_9BACT Substrate [49]
Beta-lactamase (blaB) DERPJ4F A0A2S8IKB0_BURCE Substrate [50]
Beta-lactamase (blaB) DESIWFO Q8GQK7_9FLAO Substrate [51]
Beta-lactamase (blaB) DEQX0DG Q8RIK5_FUSNN Substrate [52]
Beta-lactamase (blaB) DEBAZ7H F9DGI4_9BACT Substrate [49]
Beta-lactamase (blaB) DEA5OYT A0A4U8WDG3_9FLAO Substrate [53]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Alpha-fetoprotein (AFP) OT9GG3ZI FETA_HUMAN Gene/Protein Processing [54]
Annexin A8 (ANXA8) OTLSSQCY ANXA8_HUMAN Gene/Protein Processing [54]
ATP-binding cassette sub-family C member 4 (ABCC4) OTO27PAL MRP4_HUMAN Regulation of Drug Effects [55]
Cyclic AMP-dependent transcription factor ATF-3 (ATF3) OTC1UOHP ATF3_HUMAN Gene/Protein Processing [56]
Decorin (DCN) OTWLJL7K PGS2_HUMAN Gene/Protein Processing [54]
Glutamate--cysteine ligase regulatory subunit (GCLM) OT6CP234 GSH0_HUMAN Gene/Protein Processing [57]
Insulin-like growth factor II (IGF2) OTJ4O6MW IGF2_HUMAN Gene/Protein Processing [54]
Insulin-like growth factor-binding protein 5 (IGFBP5) OTRE5V0C IBP5_HUMAN Gene/Protein Processing [54]
Interleukin-1 beta (IL1B) OT0DWXXB IL1B_HUMAN Gene/Protein Processing [57]
Interleukin-18 (IL18) OTBB2A8O IL18_HUMAN Gene/Protein Processing [58]

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146 Functional cardiotoxicity assessment of cosmetic compounds using human-induced pluripotent stem cell-derived cardiomyocytes. Arch Toxicol. 2018 Jan;92(1):371-381.
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