Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMN4H2O)

Drug Name
Zithromax Drug Info
Synonyms
azithromycin; Zithromax; 83905-01-5; Azithromycinum; Azithromycine; Sumamed; Zitromax; Zmax; Hemomycin; Azitrocin; Azasite; Azenil; Aritromicina; Zitrotek; Zithrax; Mixoterin; Setron; Aziwok; Zitrim; Aztrin; Zifin; Tobil; Zmas; Zeto; Azithromycinum [Latin]; Azithromycine [French]; Zithromax IV; AZITHROMYCIN DIHYDRATE; Misultina; Azitromax; Z-Pak; Tromix; Aritromicina [Spanish]; Azitromicina; CP-62993; UNII-J2KLZ20U1M; DRG-0104; CCRIS 1961; HSDB 7205; Azithromycin (anhydrous); C38H72N2O12; BRN 5387583; J2KLZ20U1M; Azythromycin; CHEBI:2955
Indication
Disease Entry ICD 11 Status REF
Syphilis infection 1A6Z Approved [1]
Cross-matching ID
PubChem CID
447043
ChEBI ID
CHEBI:2955
CAS Number
CAS 83905-01-5
TTD Drug ID
DMN4H2O
INTEDE Drug ID
DR0168
ACDINA Drug ID
D00056

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Bacterial 50S ribosomal RNA (Bact 50S rRNA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [8]
Telithromycin DMZ4P3A Bacterial infection 1A00-1C4Z Approved [9]
Clarithromycin DM4M1SG Acute maxillary sinusitis Approved [10]
Dirithromycin DM0D9YJ Bacterial infection 1A00-1C4Z Approved [11]
Clindamycin DM15HL8 Acne vulgaris ED80 Approved [10]
Troleandomycin DMUZNIG Bacterial infection 1A00-1C4Z Approved [12]
Retapamulin DM9JXB7 Impetigo 1B72 Approved [13]
Dalfopristin DM4LTKV Bacterial infection 1A00-1C4Z Approved [14]
Tedizolid DMG2SKR Skin infection 1F28-1G0Z Approved [15]
Gentamicine sulfate DMBT7MI Bacterial infection 1A00-1C4Z Approved [16]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [17]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [18]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [19]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [20]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [21]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [22]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [23]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [24]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [18]
Verapamil DMA7PEW Angina pectoris BA40 Approved [25]
Eplerenone DMF0NQR Heart failure BD10-BD13 Approved [26]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [27]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [28]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [29]
Proguanil DMBL79I Malaria 1F40-1F45 Approved [30]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [30]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [31]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [32]
Capsaicin DMGMF6V Back pain ME84.Z Approved [33]
Axitinib DMGVH6N Renal cell carcinoma 2C90 Approved [34]
⏷ Show the Full List of 20 Drug(s)
Drug(s) Affected By Protein c-Fos (FOS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [35]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [36]
Verapamil DMA7PEW Angina pectoris BA40 Approved [37]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [38]
Acebutolol DM0TI4U Hypertension BA00-BA04 Approved [37]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [39]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [40]
Methotrexate DM2TEOL Anterior urethra cancer Approved [41]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [42]
Quercetin DM3NC4M Obesity 5B81 Approved [43]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interstitial collagenase (MMP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [44]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [45]
Etretinate DM2CZFA Keratosis ED56 Approved [46]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [47]
Methotrexate DM2TEOL Anterior urethra cancer Approved [48]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [49]
Quercetin DM3NC4M Obesity 5B81 Approved [50]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [51]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [52]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [53]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Stromelysin-1 (MMP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [54]
Fluvastatin DM4MDJY Arteriosclerosis BD40 Approved [54]
Pravastatin DM6A0X7 Adult acute monocytic leukemia Approved [54]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [54]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [55]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [56]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [47]
Methotrexate DM2TEOL Anterior urethra cancer Approved [57]
Quercetin DM3NC4M Obesity 5B81 Approved [58]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [51]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Growth hormone secretagogue receptor type 1 (GHSR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
DTI-015 DMXZRW0 Brain cancer 2A00 Approved [59]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [60]
AHPN DM8G6O4 Discovery agent N.A. Investigative [61]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Bacterial 50S ribosomal RNA (Bact 50S rRNA) TTUWYEA NOUNIPROTAC Modulator [2]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) Main DME DE4LYSA CP3A4_HUMAN Substrate [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Cytochrome P450 3A4 (CYP3A4) OTQGYY83 CP3A4_HUMAN Gene/Protein Processing [4]
Growth hormone secretagogue receptor type 1 (GHSR) OT1Y8ARK GHSR_HUMAN Gene/Protein Processing [5]
Interstitial collagenase (MMP1) OTI4I2V1 MMP1_HUMAN Protein Interaction/Cellular Processes [6]
Protein c-Fos (FOS) OTJBUVWS FOS_HUMAN Gene/Protein Processing [7]
Stromelysin-1 (MMP3) OTGBI74Z MMP3_HUMAN Protein Interaction/Cellular Processes [6]

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