General Information of Drug Inactive Ingredient (DIG) (ID: E00381)

DIG Name
D&C red no. 27
Synonyms
13473-26-2; D & C Red no. 27; Phloxine O; Acid Phloxine PB; Phloxine BBN Supra; Japan Red 218; Solvent Red 48; D&C Red No. 27; D&C red no.27; C.I. Solvent Red 48; C.I. 45410A; D and C Red No. 27; D&C Red 27; Red No. 218; Phloxine B (free base); UNII-2LRS185U6K; 2',4',5',7'-Tetrabromo-3,4,5,6-tetrachlorofluorescein; 2LRS185U6K; CI 45410:1; 2',4',5',7'-tetrabromo-4,5,6,7-tetrachlorofluorescein; DSSTox_CID_11089; DSSTox_RID_78862; DSSTox_GSID_31089; Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 2',4',5',7'-tetrabromo-4,5,6,7-tetrachloro-3',6'-dihydroxy-; 2,4,5,7-TETRABROMO-3,4,5,6-TETRACHLOROFLUORESCEIN; C,I, Solvent Red 48; 2',4',5',7'-tetrabromo-4,5,6,7-tetrachloro-3',6'-dihydroxy-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one; 2',4',5',7'-tetrabromo-4,5,6,7-tetrachloro-3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one; Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 2',4',5',7'-tetrabromo-4,5,6,7-tetrachloro-3',6'-dihydroxy-; CAS-13473-26-2; CCRIS 4905; EINECS 236-747-6; CI Solvent Red 48; D&C Red Dye 27; SCHEMBL111115; CHEMBL1580759; DTXSID2031089; CHEBI:156496; ZINC8830543; Tox21_202165; Tox21_303604; MFCD00067282; NCGC00091490-01; NCGC00091490-02; NCGC00091490-03; NCGC00257462-01; NCGC00259714-01; 2',4',5',7'-Tetrabromo-4,5,6,7-tetrachloro-3',6'-dihydroxyspiro(i- sobenzofuran-1(3H), 9'-(9H)xanthen)-3-one; 2',4',5',7'-Tetrabromo-4,5,6,7-tetrachloro-3',6'-dihydroxyspiro(isobenzofuran-1(3H),9'-(9H)xanthene)-3-one; 2',4',5',7'-tetrabromo-4,5,6,7-tetrachloro-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one; C.I. 45410:1; Q27254902; 2',4',5',7'-tetrabromo-3,4,5,6-tetrachlorofluorescein, AldrichCPR; 2',4',5',7'-tetrabromo-4,5,6,7-tetrachloro-3',6'-dihydroxy-3H-spiro[[2]benzofuran-1,9'-xanthen]-3-one; 2',4',5',7'-tetrabromo-4,5,6,7-tetrachloro-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one
DIG Function
Colorant
Formula
C20H4Br4Cl4O5
Canonical SMILES
C1=C2C(=C(C(=C1Br)O)Br)OC3=C(C(=C(C=C3C24C5=C(C(=C(C(=C5Cl)Cl)Cl)Cl)C(=O)O4)Br)O)Br
InChI
1S/C20H4Br4Cl4O5/c21-5-1-3-17(9(23)15(5)29)32-18-4(2-6(22)16(30)10(18)24)20(3)8-7(19(31)33-20)11(25)13(27)14(28)12(8)26/h1-2,29-30H
InChIKey
ZYIBVBKZZZDFOY-UHFFFAOYSA-N
Physicochemical Properties Molecular Weight 785.7 Topological Polar Surface Area 76
XlogP 8.7 Complexity 780
Heavy Atom Count 33 Rotatable Bond Count 0
Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 5

Full List of Drug(s) Co-administrated with This DIG

42 Approved Drug(s) Co-administrated with This DIG
Drug Name Drug ID Indication Formulation Name Formulation ID
Acetaminophen DMUIE76 Allergic rhinitis [CA08.0] Acetaminophen 160 mg tablet F00101
Amitriptyline DMK7F9S Depression [6A70-6A7Z] Amitriptyline 10 mg tablet F01011
Aspirin DM672AH Acute coronary syndrome [BA41] Aspirin 81 mg tablet F01684
Benzocaine DMI18HW Anaesthesia [9A78.6] Benzocaine 6 mg tablet F02345
Bupropion DM5PCS7 Depression [6A70-6A7Z] Bupropion 150 mg tablet F02888
Caffeine DMKBJWP Allergic rhinitis [CA08.0] Caffeine 200 mg tablet F03113
Chloroquine DMSI5CB Malaria [1F40-1F45] Chloroquine 500 mg tablet F04006
Demeclocycline DMZEPFJ Acne vulgaris [ED80] Demeclocycline 150 mg tablet F05314
Desipramine DMT2FDC Attention deficit hyperactivity disorder [6A05.Z] Desipramine 75 mg tablet F05381
Dextroamphetamine DMMIHVP Attention deficit hyperactivity disorder [6A05.Z] Dextroamphetamine 20 mg tablet F05616
Diclofenac DMPIHLS Chronic renal failure [GB61.Z] Diclofenac 100 mg tablet F05712
Diphenhydramine DMKQTBA Hyperemesis gravidarum [] Diphenhydramine 25 mg tablet F06383
Enalapril DMNFUZR Congestive heart failure [BD10] Enalapril 2.5 mg tablet F07241
Esomeprazole DM7BN0X Cystic fibrosis [CA25] Esomeprazole 20 mg tablet F07518
Estradiol DMUNTE3 Acne vulgaris [ED80] Estradiol 1 mg tablet F07549
Fluphenazine DMIT8LX Psychotic disorder [6A20-6A25] Fluphenazine 5 mg tablet F08559
Galantamine DMEO794 Alzheimer disease [8A20] Galantamine 8 mg tablet F09049
Glibenclamide DM8JXPZ Diabetic complication [5A2Y] Glyburide 2.5 mg tablet F09302
Glimepiride DM5FSJA Diabetic complication [5A2Y] Glimepiride 4 mg tablet F09184
Haloperidol DM96SE0 Delirium [] Haloperidol 2 mg tablet F09542
Ibuprofen DM8VCBE Dysmenorrhea [GA34.3] Ibuprofen 100 mg tablet F10072
Isocarboxazid DMAF1NB Depression [6A70-6A7Z] Isocarboxazid 10 mg tablet F10747
Isosorbide Mononitrate DMYLMU0 Angina pectoris [BA40] Isosorbide mononitrate 30 mg tablet F10832
Isotretinoin DM4QTBN Acne vulgaris [ED80] Isotretinoin 20 mg capsule F10867
Letrozole DMH07Y3 Estrogen-receptor positive breast cancer [] Letrozole 2.5 mg tablet F11383
Levetiracetam DMTGDN8 Epilepsy [8A60-8A68] Levetiracetam 250 mg tablet F11469
Loratadine DMF3AN7 Allergy [4A80-4A85] Loratadine 5 mg tablet F12531
Meperidine DMX4GND Pain [MG30-MG3Z] Meperidine 150 mg tablet F13015
Metoprolol DMOJ0V6 Acute coronary syndrome [BA41] Metoprolol 50 mg tablet F13909
Minocycline DMVN5OH Acne vulgaris [ED80] Minocycline 105 mg tablet F14110
Morphine DMRMS0L Advanced cancer [2A00-2F9Z] Morphine 30 mg tablet F14620
Nebivolol DM7F1PA Hypertension [BA00-BA04] Nebivolol 10 mg tablet F15126
Nifedipine DMSVOZT Angina pectoris [BA40] Nifedipine 90 mg tablet F15353
Oxycodone DMXLKHV Osteoarthritis [FA00-FA05] Oxycodone 10 mg tablet F16238
Oxymorphone DM65AGJ Pain [MG30-MG3Z] Oxymorphone 5 mg tablet F16436
Phenylephrine DMZHUO5 Allergic rhinitis [CA08.0] Phenylephrine 10 mg tablet F17201
Pramipexole DMNMW9R Parkinson disease [8A00.0] Pramipexole 1.5 mg tablet F17592
Promethazine DM6I5GR Hyperemesis gravidarum [] Promethazine 50 mg tablet F18023
Pseudoephedrine DMIVJ0D Allergic rhinitis [CA08.0] Pseudoephedrine 30 mg tablet F18244
Ropinirole DMA6S1D Parkinson disease [8A00.0] Ropinirole 0.25 mg tablet F19413
Sumatriptan DMVYXR8 Cluster headache [8A81.0] Sumatriptan 100 mg tablet F20531
Valproate DMCFE9I Epilepsy [8A60-8A68] Valproic acid 250 mg tablet F21932
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⏷ Show the Full List of 42 Approved Drug(s)
1 Investigative Drug(s) Co-administrated with This DIG
Drug Name Drug ID Indication Formulation Name Formulation ID
Oxybutynine DMJPBAX Obsolete neurogenic bladder [] Oxybutynin 5 mg tablet F16194
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