Details of the Drug Combination

General Information of Drug Combination (ID: DC09AZ0)

Drug Combination Name
Ethanol Framycetin
Indication
Disease Entry Status REF
Colorectal Neoplasms Phase 1 [1]
Component Drugs Ethanol   DMDRQZU Framycetin   DMF8DNE
Small molecular drug Small molecular drug
2D MOL 2D MOL
3D MOL 3D MOL

Molecular Interaction Atlas of This Drug Combination

Molecular Interaction Atlas (MIA)
Indication(s) of Ethanol
Disease Entry ICD 11 Status REF
Chronic pain MG30 Approved [2]
Cystic tumor of the pancreas N.A. Approved [3]
Cystitis GC00 Approved [2]
Ethanol Interacts with 1 DTT Molecule(s)
DTT Name DTT ID UniProt ID Mode of Action REF
GABA(A) receptor alpha-1 (GABRA1) TT1MPAY GBRA1_HUMAN Antagonist [17]
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Ethanol Interacts with 13 DME Molecule(s)
DME Name DME ID UniProt ID Mode of Action REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Metabolism [18]
Cytochrome P450 1A2 (CYP1A2) DEJGDUW CP1A2_HUMAN Metabolism [18]
UDP-glucuronosyltransferase 1A1 (UGT1A1) DEYGVN4 UD11_HUMAN Metabolism [19]
Cytochrome P450 2E1 (CYP2E1) DEVDYN7 CP2E1_HUMAN Metabolism [20]
Alcohol dehydrogenase class-V (ADH6) DE017IC ADH6_HUMAN Metabolism [21]
Aldo-keto reductase 1A1 (AKR1A1) DED2FW3 AK1A1_HUMAN Metabolism [21]
Alcohol dehydrogenase class-I alpha (ADH1A) DEE5M8O ADH1A_HUMAN Metabolism [22]
Alcohol dehydrogenase class-I beta (ADH1B) DEEN9RD ADH1B_HUMAN Metabolism [22]
Alcohol dehydrogenase class-I gamma (ADH1C) DEM1HNL ADH1G_HUMAN Metabolism [22]
Alcohol dehydrogenase class-II (ADH4) DEOCWU3 ADH4_HUMAN Metabolism [23]
Gastric alcohol dehydrogenase (ADH7) DEZMAHX ADH7_HUMAN Metabolism [21]
Alcohol dehydrogenase class-III (ADH5) DEIOH6A ADHX_HUMAN Metabolism [21]
Alcohol dehydrogenase (ADH) DEG8NJD A0A2I1XAT4_NEISI Metabolism [24]
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⏷ Show the Full List of 13 DME(s)
Ethanol Interacts with 406 DOT Molecule(s)
DOT Name DOT ID UniProt ID Mode of Action REF
All-trans-retinol dehydrogenase ADH1B (ADH1B) OTV3TB81 ADH1B_HUMAN Increases Expression [10]
Alcohol dehydrogenase 1C (ADH1C) OTO1DV7F ADH1G_HUMAN Increases Expression [25]
Mitogen-activated protein kinase 1 (MAPK1) OTH85PI5 MK01_HUMAN Decreases Phosphorylation [26]
Serotransferrin (TF) OT41PEMS TRFE_HUMAN Increases Expression [13]
Proenkephalin-A (PENK) OT8P3HMP PENK_HUMAN Decreases Expression [27]
Transforming growth factor beta-1 proprotein (TGFB1) OTV5XHVH TGFB1_HUMAN Increases Expression [28]
Protein-glutamine gamma-glutamyltransferase 2 (TGM2) OT6MFOWF TGM2_HUMAN Increases Expression [29]
Cytochrome b-245 heavy chain (CYBB) OTGSG868 CY24B_HUMAN Increases Expression [9]
Phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1) OTXEE550 APR_HUMAN Increases Expression [30]
Neurogenic locus notch homolog protein 3 (NOTCH3) OTMVVA7F NOTC3_HUMAN Increases Expression [30]
Aldehyde dehydrogenase, mitochondrial (ALDH2) OTKJ9I3N ALDH2_HUMAN Increases Expression [10]
Interleukin-8 (CXCL8) OTS7T5VH IL8_HUMAN Increases Secretion [25]
Protein shisa-3 homolog (SHISA3) OTE8TPCP SHSA3_HUMAN Increases Expression [11]
Cytosolic acyl coenzyme A thioester hydrolase (ACOT7) OT7C68YV BACH_HUMAN Decreases Expression [11]
Left-right determination factor 2 (LEFTY2) OT3RX4QF LFTY2_HUMAN Increases Expression [11]
TNF receptor-associated factor 5 (TRAF5) OTSBTLO0 TRAF5_HUMAN Increases Expression [11]
Class E basic helix-loop-helix protein 40 (BHLHE40) OTITX14U BHE40_HUMAN Increases Expression [11]
Copper chaperone for superoxide dismutase (CCS) OTXHT3QO CCS_HUMAN Increases Expression [11]
Centrin-3 (CETN3) OTG4PL7H CETN3_HUMAN Decreases Expression [11]
Histone H2B type 1-K (H2BC12) OTQ8V0KG H2B1K_HUMAN Decreases Expression [11]
Forkhead box protein H1 (FOXH1) OTEXJ9SL FOXH1_HUMAN Increases Expression [11]
Left-right determination factor 1 (LEFTY1) OT51HVC4 LFTY1_HUMAN Increases Expression [11]
Protein FAM13A (FAM13A) OTZ6GN0Q FA13A_HUMAN Increases Expression [11]
Lecithin retinol acyltransferase (LRAT) OTB7CJKY LRAT_HUMAN Increases Expression [11]
Heat shock 70 kDa protein 4L (HSPA4L) OT181WZB HS74L_HUMAN Increases Expression [11]
Thy-1 membrane glycoprotein (THY1) OTVONVTB THY1_HUMAN Decreases Expression [11]
Histone H2B type 1-J (H2BC11) OTGM083T H2B1J_HUMAN Decreases Expression [11]
Gamma-enolase (ENO2) OTRODL0T ENOG_HUMAN Decreases Expression [11]
Fructose-bisphosphate aldolase C (ALDOC) OTEC13I5 ALDOC_HUMAN Decreases Expression [11]
Thymosin beta-15A (TMSB15A) OTSBWCES TB15A_HUMAN Decreases Expression [11]
Cadherin-1 (CDH1) OTFJMXPM CADH1_HUMAN Decreases Expression [11]
Histone H1.2 (H1-2) OT0AVI4M H12_HUMAN Decreases Expression [11]
Heat shock 70 kDa protein 6 (HSPA6) OTH4S7WB HSP76_HUMAN Increases Expression [11]
Blood group Rh(CE) polypeptide (RHCE) OTS18IZ5 RHCE_HUMAN Decreases Expression [11]
Insulin-like growth factor-binding protein 5 (IGFBP5) OTRE5V0C IBP5_HUMAN Increases Expression [11]
5-hydroxytryptamine receptor 1D (HTR1D) OTLS74AF 5HT1D_HUMAN Increases Expression [11]
Protein-lysine 6-oxidase (LOX) OT1C2HIU LYOX_HUMAN Increases Expression [11]
M-phase inducer phosphatase 1 (CDC25A) OTSLKKCO MPIP1_HUMAN Decreases Expression [11]
Replication factor C subunit 1 (RFC1) OT3L5PK3 RFC1_HUMAN Decreases Expression [11]
Amiloride-sensitive sodium channel subunit alpha (SCNN1A) OTE2KVZV SCNNA_HUMAN Increases Expression [11]
Steroidogenic acute regulatory protein, mitochondrial (STAR) OTFEZ5AI STAR_HUMAN Decreases Expression [11]
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 (GNG4) OTOXNDI9 GBG4_HUMAN Decreases Expression [11]
Homeobox protein goosecoid (GSC) OT4DH7PR GSC_HUMAN Increases Expression [11]
Small nuclear ribonucleoprotein G (SNRPG) OTWX4XK1 RUXG_HUMAN Decreases Expression [11]
Histone H2B type 1-C/E/F/G/I (H2BC10) OTLQH0D6 H2B1C_HUMAN Decreases Expression [11]
Disabled homolog 2 (DAB2) OTRMQTMZ DAB2_HUMAN Decreases Expression [11]
POU domain, class 5, transcription factor 1 (POU5F1) OTDHHN7O PO5F1_HUMAN Increases Expression [11]
Mothers against decapentaplegic homolog 4 (SMAD4) OTWQWCKG SMAD4_HUMAN Increases Expression [11]
Protein patched homolog 1 (PTCH1) OTMG07H5 PTC1_HUMAN Increases Expression [11]
Endogenous retrovirus group 3 member 1 Env polyprotein (ERV3-1) OT4CW64T ENR1_HUMAN Increases Expression [11]
Neuronatin (NNAT) OTNRLO7G NNAT_HUMAN Decreases Expression [11]
Cyclin-G2 (CCNG2) OTII38K2 CCNG2_HUMAN Increases Expression [11]
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) OTQYEXL2 F264_HUMAN Increases Expression [11]
Leucine-rich repeat flightless-interacting protein 1 (LRRFIP1) OTN7XAUD LRRF1_HUMAN Decreases Expression [11]
Leucine-rich repeat and calponin homology domain-containing protein 2 (LRCH2) OTUEUEHY LRCH2_HUMAN Decreases Expression [11]
Gliomedin (GLDN) OTA8TQU9 GLDN_HUMAN Increases Expression [11]
Basic immunoglobulin-like variable motif-containing protein (BIVM) OTQEJWSA BIVM_HUMAN Decreases Expression [11]
Dedicator of cytokinesis protein 3 (DOCK3) OTF3YS2W DOCK3_HUMAN Increases Expression [11]
Secreted frizzled-related protein 1 (SFRP1) OT0U9G41 SFRP1_HUMAN Increases Expression [11]
Kinetochore protein Spc24 (SPC24) OT1HVYV4 SPC24_HUMAN Decreases Expression [11]
Olfactory receptor 5P3 (OR5P3) OTIXMOUN OR5P3_HUMAN Increases Expression [11]
Arrestin domain-containing protein 3 (ARRDC3) OTAKW7R9 ARRD3_HUMAN Increases Expression [11]
Dynein axonemal heavy chain 11 (DNAH11) OT6IYFVV DYH11_HUMAN Increases Expression [11]
Cysteine and tyrosine-rich protein 1 (CYYR1) OTKNFPUY CYYR1_HUMAN Decreases Expression [11]
Histone H2A type 1-H (H2AC12) OTLXVB97 H2A1H_HUMAN Decreases Expression [11]
RNA-binding protein 14 (RBM14) OTO9GMBD RBM14_HUMAN Increases Expression [11]
Histone H2B type 1-M (H2BC14) OTSDZZZY H2B1M_HUMAN Decreases Expression [11]
Kelch-like protein 4 (KLHL4) OTEFI623 KLHL4_HUMAN Increases Expression [11]
Class E basic helix-loop-helix protein 41 (BHLHE41) OTY9GJ1Y BHE41_HUMAN Increases Expression [11]
Egl nine homolog 1 (EGLN1) OT5QODDK EGLN1_HUMAN Increases Expression [11]
Centromere protein H (CENPH) OTPOO9LK CENPH_HUMAN Decreases Expression [11]
Thiol S-methyltransferase TMT1A (TMT1A) OT4IAAZP TMT1A_HUMAN Decreases Expression [11]
Homeobox protein NANOG (NANOG) OTUEY1FM NANOG_HUMAN Increases Expression [11]
Pleckstrin homology domain-containing family A member 2 (PLEKHA2) OTY2AP6T PKHA2_HUMAN Increases Expression [11]
Protein BEX1 (BEX1) OTBQIF0H BEX1_HUMAN Decreases Expression [11]
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) OTR1XD9B GPAT1_HUMAN Decreases Expression [11]
Muscleblind-like protein 3 (MBNL3) OT2T2YOK MBNL3_HUMAN Increases Expression [11]
Cell growth-regulating nucleolar protein (LYAR) OTQNA67C LYAR_HUMAN Decreases Expression [11]
PTB domain-containing engulfment adapter protein 1 (GULP1) OT1WMVDH GULP1_HUMAN Decreases Expression [11]
Claudin-16 (CLDN16) OTTHAIKR CLD16_HUMAN Increases Expression [11]
Insulin-induced gene 2 protein (INSIG2) OTX4VY51 INSI2_HUMAN Increases Expression [11]
Protein patched homolog 2 (PTCH2) OTOQ0K9V PTC2_HUMAN Decreases Expression [11]
Transcription factor p65 (RELA) OTUJP9CN TF65_HUMAN Affects Localization [31]
Nuclear factor of activated T-cells, cytoplasmic 3 (NFATC3) OTYOORME NFAC3_HUMAN Increases Expression [31]
Mitogen-activated protein kinase 8 (MAPK8) OTEREYS5 MK08_HUMAN Increases Phosphorylation [32]
Mitogen-activated protein kinase 9 (MAPK9) OTCEVJ9E MK09_HUMAN Increases Phosphorylation [32]
Cytochrome P450 4F11 (CYP4F11) OTHZ2GG2 CP4FB_HUMAN Increases Expression [32]
Synaptophysin (SYP) OTFJKMO4 SYPH_HUMAN Decreases Expression [33]
Drebrin (DBN1) OTZVKG8A DREB_HUMAN Decreases Expression [33]
Ankyrin repeat domain-containing protein 33B (ANKRD33B) OTTO39IV AN33B_HUMAN Increases Expression [12]
Elongin BC and Polycomb repressive complex 2-associated protein (EPOP) OTOYAP3V EPOP_HUMAN Increases Expression [12]
Huntingtin-interacting protein 1 (HIP1) OT7AKCFQ HIP1_HUMAN Increases Expression [12]
Homeobox protein Meis2 (MEIS2) OTG4ADLM MEIS2_HUMAN Decreases Expression [12]
Calmegin (CLGN) OTEWVFQV CLGN_HUMAN Increases Expression [12]
Prolyl 4-hydroxylase subunit alpha-2 (P4HA2) OTP45YKX P4HA2_HUMAN Increases Expression [12]
Calpain-5 (CAPN5) OTQ8QM7K CAN5_HUMAN Increases Expression [12]
Uncharacterized protein KIAA0513 (KIAA0513) OT7AVTFB K0513_HUMAN Increases Expression [12]
Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP) OTRNDZXB HNRPQ_HUMAN Decreases Expression [12]
Syndecan-3 (SDC3) OT1P0LJM SDC3_HUMAN Increases Expression [12]
Low-density lipoprotein receptor-related protein 4 (LRP4) OTO4M459 LRP4_HUMAN Increases Expression [12]
Filamin-B (FLNB) OTPCOYL6 FLNB_HUMAN Increases Expression [12]
Src kinase-associated phosphoprotein 2 (SKAP2) OTSF44KP SKAP2_HUMAN Decreases Expression [12]
Microtubule cross-linking factor 2 (MTCL2) OTYL5HK1 MTCL2_HUMAN Increases Expression [12]
Ras-related protein Rab-3D (RAB3D) OTGKRR3C RAB3D_HUMAN Increases Expression [12]
Phosphoglycerate kinase 1 (PGK1) OT6V1ICH PGK1_HUMAN Decreases Expression [12]
Plasma serine protease inhibitor (SERPINA5) OTTZXPGD IPSP_HUMAN Increases Expression [12]
Transcription factor AP-2-alpha (TFAP2A) OTMYT3NK AP2A_HUMAN Increases Expression [12]
Histone H1.0 (H1-0) OTRLJK4Z H10_HUMAN Decreases Expression [12]
Tumor necrosis factor receptor superfamily member 16 (NGFR) OTPKSM49 TNR16_HUMAN Increases Expression [12]
Apelin receptor early endogenous ligand (APELA) OTYY0P69 ELA_HUMAN Decreases Expression [12]
Protein Cripto (CRIPTO) OT46DZXJ TDGF1_HUMAN Decreases Expression [12]
Tyrosine-protein phosphatase non-receptor type 3 (PTPN3) OTSLZBVY PTN3_HUMAN Increases Expression [12]
Large ribosomal subunit protein uL13 (RPL13A) OTME3VXN RL13A_HUMAN Decreases Expression [12]
OX-2 membrane glycoprotein (CD200) OTQEQSRT OX2G_HUMAN Decreases Expression [12]
Tumor necrosis factor ligand superfamily member 9 (TNFSF9) OTV9L89D TNFL9_HUMAN Decreases Expression [12]
Chromobox protein homolog 5 (CBX5) OT8VYY84 CBX5_HUMAN Decreases Expression [12]
Transcriptional regulator ATRX (ATRX) OT77RSQW ATRX_HUMAN Decreases Expression [12]
Nuclear autoantigenic sperm protein (NASP) OTNE4THC NASP_HUMAN Decreases Expression [12]
Emerin (EMD) OTR8ZANE EMD_HUMAN Increases Expression [12]
Serpin B9 (SERPINB9) OTJ811IF SPB9_HUMAN Decreases Expression [12]
Annexin A11 (ANXA11) OT8SRY1C ANX11_HUMAN Increases Expression [12]
Heterogeneous nuclear ribonucleoprotein A3 (HNRNPA3) OT4O4NFS ROA3_HUMAN Decreases Expression [12]
Mitogen-activated protein kinase 10 (MAPK10) OTC46VX1 MK10_HUMAN Decreases Expression [12]
Activated RNA polymerase II transcriptional coactivator p15 (SUB1) OTK71JYU TCP4_HUMAN Decreases Expression [12]
CD81 antigen (CD81) OTQFXNAZ CD81_HUMAN Increases Expression [12]
Triosephosphate isomerase (TPI1) OT14KP4B TPIS_HUMAN Decreases Expression [12]
Myelin proteolipid protein (PLP1) OT8CM9CX MYPR_HUMAN Increases Expression [12]
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PPP1CB) OTYFTYFR PP1B_HUMAN Decreases Expression [12]
Rho-related GTP-binding protein RhoB (RHOB) OTHQFQF7 RHOB_HUMAN Decreases Expression [12]
Histone H4 (H4C1) OTB71W46 H4_HUMAN Decreases Expression [12]
Histone H3.1 (H3C1) OTGBGOZW H31_HUMAN Decreases Expression [12]
RNA-binding protein 3 (RBM3) OTAJ7R31 RBM3_HUMAN Decreases Expression [12]
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) OTLQN1E2 HNRPU_HUMAN Decreases Expression [12]
Peptidyl-prolyl cis-trans isomerase FKBP4 (FKBP4) OTPV1D60 FKBP4_HUMAN Increases Expression [12]
Activin receptor type-1 (ACVR1) OT4JATFE ACVR1_HUMAN Increases Expression [12]
Protocadherin-1 (PCDH1) OT7KDEL3 PCDH1_HUMAN Increases Expression [12]
Lysyl oxidase homolog 1 (LOXL1) OTA0NEJU LOXL1_HUMAN Increases Expression [12]
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3) OT4SO7J4 BNIP3_HUMAN Decreases Expression [12]
Serine/arginine-rich splicing factor 6 (SRSF6) OTGLOSYE SRSF6_HUMAN Decreases Expression [12]
Transcription initiation factor TFIID subunit 7 (TAF7) OT43QHS3 TAF7_HUMAN Decreases Expression [12]
Dixin (DIXDC1) OT87DXEG DIXC1_HUMAN Increases Expression [12]
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) OT25JBA3 F263_HUMAN Decreases Expression [12]
Protogenin (PRTG) OTDE8D9Z PRTG_HUMAN Decreases Expression [12]
N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (GNPTAB) OT2Z03OB GNPTA_HUMAN Increases Expression [12]
La-related protein 7 (LARP7) OTLLOZTL LARP7_HUMAN Decreases Expression [12]
Solute carrier family 35 member F1 (SLC35F1) OTRXHR2P S35F1_HUMAN Increases Expression [12]
EEIG family member 2 (EEIG2) OTN8R8DQ EEIG2_HUMAN Increases Expression [12]
Early estrogen-induced gene 1 protein (EEIG1) OT2BMEAE EEIG1_HUMAN Increases Expression [12]
Protein lin-9 homolog (LIN9) OTLHW00C LIN9_HUMAN Decreases Expression [12]
Complexin-2 (CPLX2) OTU5QWFH CPLX2_HUMAN Decreases Expression [12]
Oligodendrocyte transcription factor 3 (OLIG3) OTU8XLAF OLIG3_HUMAN Decreases Expression [12]
Monocarboxylate transporter 9 (SLC16A9) OTVCLKQQ MOT9_HUMAN Increases Expression [12]
L-xylulose reductase (DCXR) OTYVXRXB DCXR_HUMAN Increases Expression [12]
Choline transporter-like protein 2 (SLC44A2) OT11T33C CTL2_HUMAN Increases Expression [12]
E3 ubiquitin-protein ligase TRIM22 (TRIM22) OTJBLG5R TRI22_HUMAN Increases Expression [12]
Xaa-Arg dipeptidase (PM20D2) OTD2Y7LU P20D2_HUMAN Increases Expression [12]
Large neutral amino acids transporter small subunit 4 (SLC43A2) OTMSOSOX LAT4_HUMAN Increases Expression [12]
Refilin-B (RFLNB) OTI7ZM75 RFLB_HUMAN Increases Expression [12]
Myc target protein 1 (MYCT1) OTZ8A9L3 MYCT1_HUMAN Decreases Expression [12]
Insulin-like growth factor-binding protein-like 1 (IGFBPL1) OTY4HVN8 IBPL1_HUMAN Increases Expression [12]
TBC1 domain family member 5 (TBC1D5) OTNHLLAX TBCD5_HUMAN Increases Expression [12]
Neogenin (NEO1) OTGJ1997 NEO1_HUMAN Increases Expression [12]
Exostosin-like 1 (EXTL1) OTMSNY9N EXTL1_HUMAN Increases Expression [12]
Arylsulfatase G (ARSG) OTT7TDW7 ARSG_HUMAN Increases Expression [12]
Protein LRATD2 (LRATD2) OTEZBUUL LRAT2_HUMAN Increases Expression [12]
Transmembrane protein 237 (TMEM237) OTQEVL7L TM237_HUMAN Decreases Expression [12]
La-related protein 6 (LARP6) OTUQ9QS9 LARP6_HUMAN Increases Expression [12]
Acidic leucine-rich nuclear phosphoprotein 32 family member E (ANP32E) OTTWELUQ AN32E_HUMAN Decreases Expression [12]
TNF receptor-associated factor 4 (TRAF4) OTJLRVMC TRAF4_HUMAN Increases Expression [12]
RanBP-type and C3HC4-type zinc finger-containing protein 1 (RBCK1) OTOOXC7B HOIL1_HUMAN Increases Expression [12]
Transmembrane gamma-carboxyglutamic acid protein 4 (PRRG4) OT2SZQI7 TMG4_HUMAN Increases Expression [12]
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 (NMNAT2) OT5JLP2H NMNA2_HUMAN Increases Expression [12]
Protein Niban 1 (NIBAN1) OTYOLI12 NIBA1_HUMAN Increases Expression [12]
Thiamine transporter 2 (SLC19A3) OTOWP1CT S19A3_HUMAN Decreases Expression [12]
Homeobox protein Hox-D1 (HOXD1) OTN4V9ZF HXD1_HUMAN Decreases Expression [12]
Protein mono-ADP-ribosyltransferase PARP12 (PARP12) OTCQTYIO PAR12_HUMAN Increases Expression [12]
Probable E3 ubiquitin-protein ligase IRF2BPL (IRF2BPL) OTV8MNT1 I2BPL_HUMAN Increases Expression [12]
Nucleoporin-62 C-terminal-like protein (NUP62CL) OTEN1HET N62CL_HUMAN Increases Expression [12]
Ras association domain-containing protein 4 (RASSF4) OT7YLOFH RASF4_HUMAN Increases Expression [12]
Olfactomedin-like protein 3 (OLFML3) OTDN45FN OLFL3_HUMAN Decreases Expression [12]
Anoctamin-10 (ANO10) OTG3BNOU ANO10_HUMAN Increases Expression [12]
Dapper homolog 1 (DACT1) OT19Z704 DACT1_HUMAN Decreases Expression [12]
Bcl-2-associated transcription factor 1 (BCLAF1) OT7T8H6A BCLF1_HUMAN Decreases Expression [12]
Transcription factor CP2-like protein 1 (TFCP2L1) OT7QIJ0X TF2L1_HUMAN Increases Expression [12]
Peroxisomal sarcosine oxidase (PIPOX) OTWTCOTN SOX_HUMAN Decreases Expression [12]
Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2L) OT3HG324 ASH2L_HUMAN Increases Expression [12]
Large neutral amino acids transporter small subunit 2 (SLC7A8) OT8XXVO8 LAT2_HUMAN Increases Expression [12]
Bromodomain adjacent to zinc finger domain protein 2B (BAZ2B) OTB98CEY BAZ2B_HUMAN Decreases Expression [12]
Inhibitor of growth protein 4 (ING4) OT0VVG4V ING4_HUMAN Decreases Expression [12]
LIM and calponin homology domains-containing protein 1 (LIMCH1) OTYPC4XA LIMC1_HUMAN Decreases Expression [12]
Lysosome-associated membrane glycoprotein 3 (LAMP3) OTN0XL3W LAMP3_HUMAN Increases Expression [12]
Carbohydrate sulfotransferase 2 (CHST2) OTV11IZF CHST2_HUMAN Increases Expression [12]
Steroidogenic factor 1 (NR5A1) OTOULYR4 STF1_HUMAN Decreases Expression [34]
CCN family member 1 (CCN1) OTKJBEMD CCN1_HUMAN Decreases Expression [13]
Astrotactin-1 (ASTN1) OT23FQIB ASTN1_HUMAN Increases Expression [13]
Beta-1,4-glucuronyltransferase 1 (B4GAT1) OT5NH9TD B4GA1_HUMAN Increases Expression [13]
Growth arrest and DNA damage-inducible protein GADD45 gamma (GADD45G) OT8V1J4M GA45G_HUMAN Decreases Expression [13]
GTP-binding protein Di-Ras3 (DIRAS3) OT3XHLQA DIRA3_HUMAN Increases Expression [13]
Vitamin D-binding protein (GC) OTWS63BY VTDB_HUMAN Decreases Expression [13]
Coagulation factor XIII B chain (F13B) OTIZXROK F13B_HUMAN Decreases Expression [13]
Large ribosomal subunit protein P2 (RPLP2) OT2YBK3W RLA2_HUMAN Increases Expression [13]
Mast/stem cell growth factor receptor Kit (KIT) OTHUY3VZ KIT_HUMAN Increases Expression [13]
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MYL2) OT78PC0C MLRV_HUMAN Decreases Expression [13]
Natriuretic peptides B (NPPB) OTSN2IPY ANFB_HUMAN Decreases Expression [13]
Endothelin receptor type B (EDNRB) OTLLZV3P EDNRB_HUMAN Increases Expression [13]
CCN family member 2 (CCN2) OTC39NSU CCN2_HUMAN Decreases Expression [13]
Radiation-inducible immediate-early gene IEX-1 (IER3) OTZJI5FZ IEX1_HUMAN Decreases Expression [13]
Sodium/myo-inositol cotransporter (SLC5A3) OT6FY2KA SC5A3_HUMAN Increases Expression [13]
10 kDa heat shock protein, mitochondrial (HSPE1) OT7JSZLB CH10_HUMAN Increases Expression [13]
Collagen alpha-1(XIV) chain (COL14A1) OTLNJ13O COEA1_HUMAN Increases Expression [13]
Ankyrin repeat domain-containing protein 1 (ANKRD1) OTHJ7JV9 ANKR1_HUMAN Decreases Expression [13]
FRAS1-related extracellular matrix protein 2 (FREM2) OTEK6BZR FREM2_HUMAN Increases Expression [13]
OTU domain-containing protein 1 (OTUD1) OTE6O5XB OTUD1_HUMAN Decreases Expression [13]
Leiomodin-2 (LMOD2) OTFXHQFL LMOD2_HUMAN Decreases Expression [13]
Transmembrane protein 71 (TMEM71) OTA7W26O TMM71_HUMAN Decreases Expression [13]
Synaptotagmin-10 (SYT10) OTVV19BW SYT10_HUMAN Increases Expression [13]
Fc receptor-like A (FCRLA) OT6MK4M1 FCRLA_HUMAN Decreases Expression [13]
Monocarboxylate transporter 14 (SLC16A14) OTUGDEUV MOT14_HUMAN Increases Expression [13]
Retrotransposon-derived protein PEG10 (PEG10) OTWD2278 PEG10_HUMAN Increases Expression [13]
Dynein axonemal assembly factor 3 (DNAAF3) OT3OHO0O DAAF3_HUMAN Decreases Expression [13]
Arrestin domain-containing protein 4 (ARRDC4) OTINJ0FX ARRD4_HUMAN Increases Expression [13]
EMI domain-containing protein 1 (EMID1) OTJ27FQ1 EMID1_HUMAN Increases Expression [13]
BTB/POZ domain-containing protein KCTD12 (KCTD12) OTPYKT4Z KCD12_HUMAN Increases Expression [13]
Chemokine-like protein TAFA-4 (TAFA4) OT0RHMNG TAFA4_HUMAN Increases Expression [13]
Hemicentin-1 (HMCN1) OTLZAS0P HMCN1_HUMAN Increases Expression [13]
SPARC-related modular calcium-binding protein 1 (SMOC1) OTJG2JQY SMOC1_HUMAN Increases Expression [13]
Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A) OT5V52LN TNR12_HUMAN Decreases Expression [13]
Inward rectifier potassium channel 16 (KCNJ16) OT174UPV KCJ16_HUMAN Decreases Expression [13]
Kv channel-interacting protein 2 (KCNIP2) OTY4BLOJ KCIP2_HUMAN Increases Expression [13]
Ras-like protein family member 12 (RASL12) OTNAK9X4 RASLC_HUMAN Increases Expression [13]
Potassium voltage-gated channel subfamily G member 1 (KCNG1) OTZ9ZRG8 KCNG1_HUMAN Increases Expression [13]
Probable small intestine urate exporter (SLC17A4) OTFOOYB9 S17A4_HUMAN Decreases Expression [13]
Myosin-4 (MYH4) OT4657W4 MYH4_HUMAN Decreases Expression [13]
Scinderin (SCIN) OT6U09OL SCIN_HUMAN Increases Expression [13]
Dynamin-1-like protein (DNM1L) OTXK1Q1G DNM1L_HUMAN Increases Expression [35]
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 (PLOD2) OTKOZRZP PLOD2_HUMAN Increases Expression [36]
Myc box-dependent-interacting protein 1 (BIN1) OTK8O0X8 BIN1_HUMAN Increases Expression [15]
Stearoyl-CoA desaturase (SCD) OTB1073G SCD_HUMAN Increases Expression [37]
Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) OTA1CPBV TR10B_HUMAN Increases Expression [38]
Histone-lysine N-methyltransferase SETD1A (SETD1A) OTVVWRIC SET1A_HUMAN Decreases Expression [38]
Phospholipid scramblase 1 (PLSCR1) OTGY9B5T PLS1_HUMAN Affects Expression [14]
Matrilin-3 (MATN3) OTH9H74J MATN3_HUMAN Decreases Expression [15]
ATP-binding cassette sub-family C member 3 (ABCC3) OTC3IJV4 MRP3_HUMAN Increases Expression [39]
Histone-lysine N-methyltransferase SUV39H1 (SUV39H1) OTDTF5BU SUV91_HUMAN Increases Expression [38]
Forkhead box protein O3 (FOXO3) OTHXQG4P FOXO3_HUMAN Increases Phosphorylation [40]
5-hydroxymethyl-dUMP N-hydrolase (DNPH1) OTEZVTI1 DNPH1_HUMAN Decreases Expression [41]
E3 ubiquitin-protein ligase parkin (PRKN) OTJBN41W PRKN_HUMAN Decreases Expression [42]
Dynamin-like 120 kDa protein, mitochondrial (OPA1) OTJGNWPW OPA1_HUMAN Decreases Expression [35]
Liprin-alpha-4 (PPFIA4) OTWXG0DO LIPA4_HUMAN Decreases Expression [15]
Serine/threonine-protein kinase/endoribonuclease IRE1 (ERN1) OTY9R6FZ ERN1_HUMAN Increases Expression [43]
Nuclear receptor subfamily 1 group I member 2 (NR1I2) OTC5U0N5 NR1I2_HUMAN Increases Expression [39]
Cell cycle checkpoint protein RAD17 (RAD17) OT1I93DT RAD17_HUMAN Decreases Expression [15]
Solute carrier organic anion transporter family member 2B1 (SLCO2B1) OTERJ4VQ SO2B1_HUMAN Increases Expression [39]
Aflatoxin B1 aldehyde reductase member 3 (AKR7A3) OTW3GO4Y ARK73_HUMAN Decreases Expression [15]
6-phosphogluconolactonase (PGLS) OTO6C0IQ 6PGL_HUMAN Increases Expression [15]
Bile salt export pump (ABCB11) OTRU7THO ABCBB_HUMAN Decreases Expression [38]
Ubiquitin-like modifier-activating enzyme ATG7 (ATG7) OTVT4YA1 ATG7_HUMAN Increases Expression [44]
Phospholipid-transporting ATPase ABCA1 (ABCA1) OT94G6BQ ABCA1_HUMAN Decreases Expression [45]
Claudin-14 (CLDN14) OTS7GKOI CLD14_HUMAN Increases Expression [46]
Pro-opiomelanocortin (POMC) OTV41F7T COLI_HUMAN Decreases Expression [27]
Proenkephalin-B (PDYN) OTEJ6430 PDYN_HUMAN Decreases Expression [27]
C-reactive protein (CRP) OT0RFT8F CRP_HUMAN Increases Expression [47]
Ferritin light chain (FTL) OTYQA8A6 FRIL_HUMAN Increases Expression [48]
Ferritin heavy chain (FTH1) OT6IFS0O FRIH_HUMAN Decreases Expression [42]
Thymidine kinase, cytosolic (TK1) OTY5JFM1 KITH_HUMAN Decreases Activity [49]
Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1) OTM0GDTP IF2A_HUMAN Increases Expression [43]
Keratin, type I cytoskeletal 18 (KRT18) OTVLQFIP K1C18_HUMAN Increases Expression [15]
Collagen alpha-2(V) chain (COL5A2) OT5VOSQE CO5A2_HUMAN Increases Expression [46]
Tyrosine-protein kinase Fyn (FYN) OTLSLVZS FYN_HUMAN Increases Phosphorylation [50]
ATP synthase subunit beta, mitochondrial (ATP5F1B) OTLFZUQK ATPB_HUMAN Increases Expression [15]
Alpha-enolase (ENO1) OTB1KWJS ENOA_HUMAN Decreases Expression [15]
Calpain-1 catalytic subunit (CAPN1) OTK6OQZR CAN1_HUMAN Increases Expression [51]
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Increases Expression [52]
Interleukin-3 (IL3) OT0CQ35N IL3_HUMAN Increases Expression [53]
SPARC (SPARC) OTPN90H0 SPRC_HUMAN Increases Expression [48]
Poly polymerase 1 (PARP1) OT310QSG PARP1_HUMAN Increases Cleavage [54]
Chorionic somatomammotropin hormone 1 (CSH1) OT33HTRR CSH1_HUMAN Decreases Expression [15]
Heat shock cognate 71 kDa protein (HSPA8) OTJI2RCI HSP7C_HUMAN Increases Expression [55]
Acetylcholine receptor subunit beta (CHRNB1) OTTJXD24 ACHB_HUMAN Decreases Expression [15]
C-C motif chemokine 2 (CCL2) OTAD2HEL CCL2_HUMAN Increases Expression [56]
C-C motif chemokine 5 (CCL5) OTSCA5CK CCL5_HUMAN Increases Secretion [57]
Glial fibrillary acidic protein (GFAP) OTQ01ZAS GFAP_HUMAN Increases Expression [15]
POU domain, class 2, transcription factor 1 (POU2F1) OTK7ELJ0 PO2F1_HUMAN Decreases Expression [41]
Ezrin (EZR) OTHBPF1Z EZRI_HUMAN Increases Expression [58]
Histone H2AX (H2AX) OT18UX57 H2AX_HUMAN Increases Expression [59]
Cyclic AMP-dependent transcription factor ATF-4 (ATF4) OTRFV19J ATF4_HUMAN Increases Expression [43]
Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A) OT2D9DOV TNR1A_HUMAN Increases Expression [53]
Spermidine synthase (SRM) OT4N5MDP SPEE_HUMAN Decreases Expression [15]
Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) OTDS2EAR TNR1B_HUMAN Increases Expression [53]
Alpha-(1,3)-fucosyltransferase 4 (FUT4) OTIBXRTL FUT4_HUMAN Increases Expression [60]
Sterol carrier protein 2 (SCP2) OTPAFCPQ SCP2_HUMAN Decreases Expression [15]
Galanin peptides (GAL) OTB3VPTO GALA_HUMAN Increases Expression [59]
Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) OTBZKX4P ROA2_HUMAN Increases Expression [15]
Protein S100-A4 (S100A4) OTLRGFSQ S10A4_HUMAN Increases Expression [48]
Beta-crystallin B3 (CRYBB3) OTTGTQIQ CRBB3_HUMAN Decreases Expression [41]
Mitogen-activated protein kinase 3 (MAPK3) OTCYKGKO MK03_HUMAN Decreases Expression [41]
Endoplasmic reticulum resident protein 29 (ERP29) OTNKANMH ERP29_HUMAN Increases Expression [15]
Peroxiredoxin-6 (PRDX6) OTS8KC8A PRDX6_HUMAN Decreases Expression [15]
G1/S-specific cyclin-D2 (CCND2) OTDULQF9 CCND2_HUMAN Decreases Expression [61]
M-phase inducer phosphatase 2 (CDC25B) OT12MSRY MPIP2_HUMAN Increases Expression [15]
Cadherin-5 (CDH5) OTVX0E1Q CADH5_HUMAN Increases Uptake [62]
DNA damage-inducible transcript 3 protein (DDIT3) OTI8YKKE DDIT3_HUMAN Increases Expression [43]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Increases Expression [59]
Kappa-type opioid receptor (OPRK1) OTXCZF4L OPRK_HUMAN Decreases Expression [27]
Reduced folate transporter (SLC19A1) OTWB0BTO S19A1_HUMAN Decreases Expression [63]
Cyclin-dependent kinase inhibitor 2A (CDKN2A) OTN0ZWAE CDN2A_HUMAN Increases Expression [59]
F-actin-capping protein subunit beta (CAPZB) OTF1A4N0 CAPZB_HUMAN Increases Expression [15]
Amphiphysin (AMPH) OTWPGWZX AMPH_HUMAN Decreases Expression [15]
CCAAT/enhancer-binding protein alpha (CEBPA) OTOM9OE4 CEBPA_HUMAN Increases Expression [64]
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) OTI862QH CPT1A_HUMAN Decreases Expression [65]
Eotaxin (CCL11) OT3BIFPK CCL11_HUMAN Decreases Expression [53]
Mismatch repair endonuclease PMS2 (PMS2) OTNLWTMI PMS2_HUMAN Decreases Expression [41]
GTP-binding protein RAD (RRAD) OTW2O4GD RAD_HUMAN Decreases Expression [41]
Sodium/calcium exchanger 3 (SLC8A3) OTIVTE0G NAC3_HUMAN Increases Expression [51]
Sestrin-2 (SESN2) OT889IXY SESN2_HUMAN Decreases Expression [66]
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) OTNPRM8U HNRPK_HUMAN Increases Expression [15]
Histone-lysine N-methyltransferase 2A (KMT2A) OT9GLJI6 KMT2A_HUMAN Decreases Expression [38]
Peroxiredoxin-1 (PRDX1) OTZ3BEC4 PRDX1_HUMAN Increases Expression [15]
Complement component 1 Q subcomponent-binding protein, mitochondrial (C1QBP) OTPYQX3K C1QBP_HUMAN Decreases Expression [15]
Tight junction protein ZO-1 (TJP1) OTBDCUPK ZO1_HUMAN Decreases Expression [67]
DNA polymerase epsilon catalytic subunit A (POLE) OTFM3MMU DPOE1_HUMAN Decreases Expression [15]
AP-1 complex subunit beta-1 (AP1B1) OTY0K84R AP1B1_HUMAN Increases Expression [15]
Acetyl-CoA carboxylase 1 (ACACA) OT5CQPZY ACACA_HUMAN Decreases Phosphorylation [68]
Stromal interaction molecule 1 (STIM1) OT8CLQ1W STIM1_HUMAN Increases Expression [69]
Pro-interleukin-16 (IL16) OTZ2MO6B IL16_HUMAN Decreases Expression [53]
Protein scribble homolog (SCRIB) OTW4N3FV SCRIB_HUMAN Decreases Expression [15]
Protein-tyrosine kinase 2-beta (PTK2B) OTGAS0I8 FAK2_HUMAN Increases Phosphorylation [50]
Caprin-1 (CAPRIN1) OTEJAMS3 CAPR1_HUMAN Increases Expression [14]
Phosphatidate phosphatase LPIN1 (LPIN1) OTQ75KF2 LPIN1_HUMAN Increases Expression [64]
Glycine N-methyltransferase (GNMT) OT0O2OQO GNMT_HUMAN Increases Expression [46]
Nuclear factor of activated T-cells, cytoplasmic 4 (NFATC4) OTTDCUAO NFAC4_HUMAN Increases Expression [59]
Retinoblastoma-binding protein 5 (RBBP5) OT12W2MK RBBP5_HUMAN Increases Expression [38]
Calponin-3 (CNN3) OTJTAXAP CNN3_HUMAN Decreases Expression [15]
Myosin light chain kinase, smooth muscle (MYLK) OT78QB4A MYLK_HUMAN Increases Expression [67]
Frataxin, mitochondrial (FXN) OTE9U09A FRDA_HUMAN Affects Expression [70]
Occludin (OCLN) OTSUTVWL OCLN_HUMAN Decreases Expression [67]
Centrosomal protein of 55 kDa (CEP55) OTGSG2PA CEP55_HUMAN Decreases Expression [15]
F-box/WD repeat-containing protein 9 (FBXW9) OTM2MFOF FBXW9_HUMAN Decreases Expression [15]
Dual specificity phosphatase 29 (DUSP29) OTJOJZHG DUS29_HUMAN Increases Expression [15]
Coiled-coil domain-containing protein 70 (CCDC70) OTQMZUYJ CCD70_HUMAN Decreases Expression [15]
Inactive caspase-12 (CASP12) OTY2W6FG CASPC_HUMAN Increases Activity [43]
Hsp90 co-chaperone Cdc37-like 1 (CDC37L1) OTGKTFAC CD37L_HUMAN Decreases Expression [48]
Autophagy-related protein 9A (ATG9A) OTAZWZH7 ATG9A_HUMAN Decreases Expression [15]
Mitofusin-1 (MFN1) OTCBXQZF MFN1_HUMAN Decreases Expression [35]
Stromal membrane-associated protein 1 (SMAP1) OTQN3BVL SMAP1_HUMAN Increases Expression [15]
Inactive histone-lysine N-methyltransferase 2E (KMT2E) OTYOLNOG KMT2E_HUMAN Decreases Expression [38]
Mixed lineage kinase domain-like protein (MLKL) OTDSLC81 MLKL_HUMAN Increases Phosphorylation [71]
Histone-lysine N-methyltransferase 2C (KMT2C) OTC59BCO KMT2C_HUMAN Decreases Expression [38]
Coiled-coil alpha-helical rod protein 1 (CCHCR1) OT22C116 CCHCR_HUMAN Decreases Expression [15]
Transcription factor IIIB 90 kDa subunit (BRF1) OTQC6DMG TF3B_HUMAN Increases Expression [72]
Calcium release-activated calcium channel protein 1 (ORAI1) OT2VE9UU CRCM1_HUMAN Increases Expression [69]
Kremen protein 1 (KREMEN1) OTGJFSAC KREM1_HUMAN Decreases Expression [15]
Nectin-4 (NECTIN4) OTJSFW1L NECT4_HUMAN Decreases Expression [46]
NACHT, LRR and PYD domains-containing protein 3 (NLRP3) OTZM6MHU NLRP3_HUMAN Increases Expression [71]
Bile acid receptor (NR1H4) OTWZLPTB NR1H4_HUMAN Decreases Expression [65]
Histone-lysine N-methyltransferase SETDB2 (SETDB2) OTBVVP9Q SETB2_HUMAN Decreases Expression [38]
Prefoldin subunit 5 (PFDN5) OTTKPTUP PFD5_HUMAN Decreases Expression [41]
tRNA-specific adenosine deaminase 1 (ADAT1) OTCDIRF4 ADAT1_HUMAN Decreases Expression [48]
Serine/threonine-protein kinase PINK1, mitochondrial (PINK1) OT50NR57 PINK1_HUMAN Decreases Expression [42]
Fanconi anemia group D2 protein (FANCD2) OTVEB5LF FACD2_HUMAN Increases Expression [73]
Microtubule-associated proteins 1A/1B light chain 3B (MAP1LC3B) OTUYHB84 MLP3B_HUMAN Increases Expression [44]
Autophagy protein 5 (ATG5) OT4T5SMS ATG5_HUMAN Decreases Expression [74]
Leucine-rich melanocyte differentiation-associated protein (LRMDA) OTIPNKTU LRMDA_HUMAN Increases Expression [46]
Histone-lysine N-methyltransferase SUV39H2 (SUV39H2) OTU0F4LL SUV92_HUMAN Decreases Expression [38]
Prokineticin-2 (PROK2) OT70IFEZ PROK2_HUMAN Increases Expression [14]
Glyoxalase domain-containing protein 4 (GLOD4) OTBJKFXA GLOD4_HUMAN Decreases Expression [15]
N-lysine methyltransferase KMT5A (KMT5A) OTW2A5YY KMT5A_HUMAN Decreases Expression [38]
StAR-related lipid transfer protein 7, mitochondrial (STARD7) OTDUZ296 STAR7_HUMAN Decreases Expression [15]
Histone-lysine N-methyltransferase ASH1L (ASH1L) OTUT5NLJ ASH1L_HUMAN Decreases Expression [38]
N-lysine methyltransferase SMYD2 (SMYD2) OTN8035R SMYD2_HUMAN Decreases Expression [38]
Phospholipid scramblase 3 (PLSCR3) OTJ6K2XJ PLS3_HUMAN Increases Expression [15]
Interleukin-1 receptor-associated kinase 4 (IRAK4) OT9JTJWC IRAK4_HUMAN Increases Expression [75]
Eukaryotic translation initiation factor 2-alpha kinase 3 (EIF2AK3) OT0DZGY4 E2AK3_HUMAN Increases Expression [43]
DNA (DNMT3B) OTZ0JCNP DNM3B_HUMAN Affects Expression [38]
Tripartite motif-containing protein 10 (TRIM10) OTEO4UCZ TRI10_HUMAN Increases Expression [15]
Apoptosis-associated speck-like protein containing a CARD (PYCARD) OT67RON3 ASC_HUMAN Increases Expression [76]
Histone-lysine N-methyltransferase 2B (KMT2B) OTMMAZQX KMT2B_HUMAN Decreases Expression [38]
Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2) OTW8V2V1 ABCG2_HUMAN Increases Expression [39]
Dystrobrevin alpha (DTNA) OTVBIRH2 DTNA_HUMAN Increases Expression [15]
Receptor-interacting serine/threonine-protein kinase 3 (RIPK3) OTL1D484 RIPK3_HUMAN Increases Expression [77]
DNA (DNMT3A) OTEJP0GH DNM3A_HUMAN Affects Expression [38]
Regenerating islet-derived protein 3-alpha (REG3A) OT0BVQRB REG3A_HUMAN Increases ADR [78]
Mu-type opioid receptor (OPRM1) OT16AAT8 OPRM_HUMAN Increases Response To Substance [79]
2'-5'-oligoadenylate synthase 3 (OAS3) OT6E5FYS OAS3_HUMAN Affects Response To Substance [64]
Mitochondrial 2-oxoglutarate/malate carrier protein (SLC25A11) OT7EVFBK M2OM_HUMAN Increases ADR [78]
Neuronal cell adhesion molecule (NRCAM) OT80HHQ2 NRCAM_HUMAN Increases Response To Substance [80]
GABA receptor subunit B1 (GABAB1) OT8KS945 M9TEZ7_TETCI Increases ADR [78]
Serine protease 1 (PRSS1) OTA425AX TRY1_HUMAN Increases ADR [81]
D(2) dopamine receptor (DRD2) OTBLXKEG DRD2_HUMAN Increases ADR [78]
Eukaryotic translation initiation factor 4E (EIF4E) OTDAWNLA IF4E_HUMAN Increases ADR [78]
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (PIK3C2A) OTFBU4GD P3C2A_HUMAN Increases ADR [78]
Small ribosomal subunit protein eS6z (RPS6A) OTIG8G1R RS61_ARATH Increases ADR [78]
Ankyrin-3 (ANK3) OTJ3IRBP ANK3_HUMAN Affects Response To Substance [82]
MORC family CW-type zinc finger protein 4 (MORC4) OTJBEHNE MORC4_HUMAN Increases ADR [81]
Protein c-Fos (FOS) OTJBUVWS FOS_HUMAN Increases ADR [78]
Coiled-coil domain-containing protein 63 (CCDC63) OTKDRXAE CCD63_HUMAN Affects Response To Substance [64]
Low-density lipoprotein receptor-related protein 6 (LRP6) OTM7PSUR LRP6_HUMAN Decreases Response To Substance [83]
3',5'-cyclic-AMP phosphodiesterase 4B (PDE4B) OTOA8WU2 PDE4B_HUMAN Affects Response To Substance [84]
Cyclin-dependent kinase 20 (CDK20) OTOLNN68 CDK20_HUMAN Affects Response To Substance [84]
Sex hormone-binding globulin (SHBG) OTPWU5IW SHBG_HUMAN Increases ADR [78]
Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH1R) OTQF5ZAK PTH1R_HUMAN Increases ADR [78]
Opioid growth factor receptor (OGFR) OTROS6RJ OGFR_HUMAN Increases ADR [78]
Period circadian protein homolog 2 (PER2) OTU2B1DJ PER2_HUMAN Affects Response To Substance [85]
T-box transcription factor TBX19 (TBX19) OTXEMR2U TBX19_HUMAN Affects Response To Substance [84]
Protein DEK (DEK) OTYCJ5H6 DEK_HUMAN Increases Secretion [86]
Catenin beta-1 (CTNNB1) OTZ932A3 CTNB1_HUMAN Affects Response To Substance [87]
------------------------------------------------------------------------------------
⏷ Show the Full List of 406 DOT(s)
Indication(s) of Framycetin
Disease Entry ICD 11 Status REF
Acute liver failure DB91 Approved [4]
Alcoholic cirrhosis of liver DB94 Approved [4]
Bacterial infection 1A00-1C4Z Approved [5]
Blepharoconjunctivitis N.A. Approved [6]
Corneal abrasion NA06.4 Approved [6]
Hepatic coma N.A. Approved [6]
Hepatic encephalopathy DB99.5 Approved [6]
Keratitis N.A. Approved [7]
Urinary tract infection GC08 Approved [8]
Uveitis 9A96.Z Investigative [6]
Framycetin Interacts with 2 DTT Molecule(s)
DTT Name DTT ID UniProt ID Mode of Action REF
Bacterial 16S ribosomal RNA (Bact 16S rRNA) TT38DW5 NOUNIPROTAC Binder [88]
Staphylococcus 30S ribosomal subunit (Stap-coc pbp2) TTQ8KVI F4NA87_STAAU Binder [89]
------------------------------------------------------------------------------------
Framycetin Interacts with 2 DME Molecule(s)
DME Name DME ID UniProt ID Mode of Action REF
Aminoglycoside O-phosphotransferase (aphA6) DEWPAJD KKA6_ACIBA Metabolism [90]
Aminoglycoside N-acetyltransferase (aacC2) DEJADS9 AAC6_ACIBA Metabolism [90]
------------------------------------------------------------------------------------
Framycetin Interacts with 2 DOT Molecule(s)
DOT Name DOT ID UniProt ID Mode of Action REF
N-alpha-acetyltransferase 15, NatA auxiliary subunit (NAA15) OT53SIZG NAA15_HUMAN Increases ADR [78]
Glial fibrillary acidic protein (GFAP) OTQ01ZAS GFAP_HUMAN Increases ADR [78]
------------------------------------------------------------------------------------

References

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3 Ethanol FDA Label
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