Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM6VM38)

Drug Name
Reserpine Drug Info
Synonyms
Abesta; Abicol; Adelfan; Adelphin; Alkarau; Alkaserp; Alserin; Apoplon; Apsical; Ascoserp; Ascoserpina; Austrapine; Banasil; Banisil; Benazyl; Bioserpine; Brinderdin; Briserine; Broserpine; Cardioserpin; Carditivo; Carpacil; Carrserp; Darebon; Deserpine; Dralserp; Eberpine; Eberspine; Ebserpine; Elfanex; Elserpine; Enipresser; Escaspere; Eserpine; Eskaserp; Eskaserpine; Gammaserpine; Gilucard; Helfoserpin; Hexaplin; Hiposerpil; Hiserpia; Hydropine; Hydroserp; Hypersil; Hypersine; Hypertensan; Idoserp; Idsoserp; Interpina; Kitine; Klimanosid; Lemiserp; Loweserp; Mallopress; Maviserpin; Mayserpine; Mephaserpin; Modenol; Naquival; Nembuserpin; Neoserfin; Neoserp; Neoslowten; Orthoserpina; Perskleran; Pressimedin; Purserpine; Quiescin; Raucap; Raudiford; Raudixin; Raudixoid; Raugal; Raulen; Rauloydin; Raumorine; Raunervil; Raunorine; Raunova; Raupasil; Raupoid; Raurine; Rausan; Rausedan; Rausedil; Rausedyl; Rauserpin; Rauserpine; Rauserpol; Rausingle; Rautrin; Rauvlid; Rauwasedin; Rauwilid; Rauwiloid; Rauwipur; Rauwita; Rauwoleaf; Rawilid; Recipin; Regroton; Resaltex; Resedrex; Resedril; Reserbal; Resercaps; Resercen; Reserfia; Reserjen; Reserlor; Reserp; Reserpal; Reserpamed; Reserpanca; Reserpene; Reserpex; Reserpidefe; Reserpil; Reserpin; Reserpina; Reserpinum; Reserpka; Reserpoid; Reserpur; Reserutin; Resiatric; Residin; Residine; Resine; Resocalm; Resperin; Resperine; Respital; Restran; Rezerpin; Riserpa; Rivased; Rivasin; Rolserp; Roxel; Roxinoid; Roxynoid; Ryser; Salupres; Sandril; Sandron; Sedaraupin; Sedaraupina; Sederaupin; Sedserp; Seominal; Serfin; Serfolia; Serolfia; Serpalan; Serpaloid; Serpaneurona; Serpanray; Serpasil; Serpasol; Serpate; Serpazil; Serpazol; Serpedin; Serpen; Serpena; Serpentil; Serpentin; Serpentina; Serpicon; Serpil; Serpiloid; Serpilum; Serpine; Serpipur; Serpivate; Serpivite; Serpogen; Serpoid; Serpone; Serpyrit; Sertabs; Sertens; Sertensin; Sertina; Supergan; Tefaserpina; Temposerpine; Tensanyl; Tenserpinie; Tensional; Tensionorme; Tepserpine; Terbolan; Transerpin; Triserpin; Tylandril; Unilord; Unipres; VIXO; Esc aspere; Hydromox R; Hypercal B; Loweser p; Neose rfin; Rau sedyl; Renese R; Rese rpamed; Se rpate; V Serp; VI XO; Diupres 250; Diupres 500; ENT 50146; H 520; Hydropres 25; Hydropres 50; Hydrosine 25; R 0875; Apoplon (TN); Diupres-250; Diupres-500; Diurese-R; Diutensen-R; HYDRO-RESERP; Hydrap-ES; Hydromox-R; Key-serpine; L-Carpserp; Neo-serp; Rau-Sed; Renese-R; Rese-lar; Reser-ar; SK-Reserpine; T-Serp; Usaf cb-27; V-Serp; Vio-Serpine; Cam-Ap-Es; L"-Carpserp; R-e-s; Ser-A-Gen; 3P Reserp
Indication
Disease Entry ICD 11 Status REF
Hypertension BA00-BA04 Approved [1]
Malignant essential hypertension BA00 Approved [2]
Psychotic disorder 6A20-6A25 Approved [2]
Therapeutic Class
Antihypertensive Agents
Cross-matching ID
PubChem CID
5770
ChEBI ID
CHEBI:28487
CAS Number
CAS 50-55-5
TTD Drug ID
DM6VM38
VARIDT Drug ID
DR00636
INTEDE Drug ID
DR2310
ACDINA Drug ID
D00588

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Synaptic vesicle amine transporter (SLC18A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Deutetrabenazine DMUPFLI Huntington disease 8A01.10 Approved [13]
Tetrabenazine DMYWQ0O Huntington disease 8A01.10 Approved [3]
Alseroxylon DMB47TQ Hypertension BA00-BA04 Approved [14]
Valbenazine Tosylate DMQSA2V Tardive dyskinesia 8A02.10 Approved [13]
Alkavervir DMB4HFI High blood pressure BA00 Approved [13]
Ingrezza DMVPLNC Tardive dyskinesia 8A02.10 Phase 4 [15]
NBI-98854 DMVO1C0 Movement disorder 8A07-8A0Z Phase 3 [16]
AV 133 DM0EQ9X Alzheimer disease 8A20 Phase 3 [17]
Lobeline DMT3KB4 Substance use disorder 6C4Z Phase 2 [18]
SOM3355 DMKCBSM Huntington disease 8A01.10 Phase 2 [19]
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Drug(s) Transported By P-glycoprotein 1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [20]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [21]
Methotrexate DM2TEOL Anterior urethra cancer Approved [4]
Folic Acid DMEMBJC Colorectal carcinoma Approved [22]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [4]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [4]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [23]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [4]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [24]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [25]
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Drug(s) Transported By Breast cancer resistance protein (ABCG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [26]
Methotrexate DM2TEOL Anterior urethra cancer Approved [27]
Folic Acid DMEMBJC Colorectal carcinoma Approved [28]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [29]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [30]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [31]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [32]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [31]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [33]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [34]
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Drug(s) Affected By ATP-dependent translocase ABCB1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [35]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [36]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [37]
Lamotrigine DM8SXYG Bipolar disorder 6A60 Approved [38]
Cepharanthine DM9Y5JB N. A. N. A. Approved [39]
Itraconazole DMCR1MV Aspergillosis 1F20 Approved [40]
Clozapine DMFC71L Schizophrenia 6A20 Approved [41]
Midostaurin DMI6E0R Acute myeloid leukaemia 2A60 Approved [42]
Trifluoperazine DMKBYWI Anxiety Approved [43]
Olanzapine DMPFN6Y Bipolar depression Approved [41]
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Drug(s) Affected By Pro-neuropeptide Y (NPY)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Mifepristone DMGZQEF Cushing disease 5A70 Approved [6]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [44]
Panobinostat DM58WKG Chronic graft versus host disease Approved [45]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [46]
Guanethidine DM9NSWT Moderate and severe hypertension BA00.Z Approved [47]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [48]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [49]
Orlistat DMRJSP8 Obesity 5B81 Approved [50]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [51]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [45]
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Drug(s) Affected By Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [52]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [53]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [54]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [55]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [56]
Chloroquine DMSI5CB Malaria 1F40-1F45 Approved [57]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [58]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [59]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [60]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [61]
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Drug(s) Affected By Adenylate cyclase type 1 (ADCY1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [62]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [44]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [63]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [48]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [63]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [63]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [64]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [58]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [65]
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Drug(s) Affected By Cytochrome P450 3A5 (CYP3A5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Eplerenone DMF0NQR Heart failure BD10-BD13 Approved [66]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [67]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [68]
Ritonavir DMU764S Human immunodeficiency virus infection 1C62 Approved [68]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [69]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [70]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [71]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [53]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [54]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [72]
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Drug(s) Affected By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Eplerenone DMF0NQR Heart failure BD10-BD13 Approved [66]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [67]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [73]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [74]
Proguanil DMBL79I Malaria 1F40-1F45 Approved [75]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [75]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [76]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [68]
Capsaicin DMGMF6V Back pain ME84.Z Approved [77]
Axitinib DMGVH6N Renal cell carcinoma 2C90 Approved [78]
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Drug(s) Affected By Bile salt export pump (ABCB11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [10]
Ezetimibe DM7A8TW Atherosclerosis BD40 Approved [79]
Glipizide DMZA5PQ Diabetic complication 5A2Y Approved [79]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [80]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [10]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [79]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [81]
Gefitinib DM15F0X Colon adenocarcinoma Approved [10]
Drospirenone DM1A9W3 Acne vulgaris ED80 Approved [82]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [10]
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Drug(s) Affected By Aldo-keto reductase family 1 member B10 (AKR1B10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [83]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [84]
Quercetin DM3NC4M Obesity 5B81 Approved [52]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [85]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [86]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [87]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [88]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [90]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [54]
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Drug(s) Affected By Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 (GCNT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [91]
Quercetin DM3NC4M Obesity 5B81 Approved [52]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [92]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [93]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [63]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [94]
Leflunomide DMR8ONJ Arthritis FA20 Approved [95]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [53]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [54]
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Drug(s) Affected By Sequestosome-1 (SQSTM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [96]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [97]
Gefitinib DM15F0X Colon adenocarcinoma Approved [98]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [99]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [100]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [101]
Methotrexate DM2TEOL Anterior urethra cancer Approved [102]
Quercetin DM3NC4M Obesity 5B81 Approved [52]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [103]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [104]
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Drug(s) Affected By Baculoviral IAP repeat-containing protein 5 (BIRC5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [105]
Gefitinib DM15F0X Colon adenocarcinoma Approved [106]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [107]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [108]
Etretinate DM2CZFA Keratosis ED56 Approved [109]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [101]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [110]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [111]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [113]
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Drug(s) Affected By Myc proto-oncogene protein (MYC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [114]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [115]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [116]
Gefitinib DM15F0X Colon adenocarcinoma Approved [117]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [118]
Selenium DM25CGV N. A. N. A. Approved [119]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [120]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [121]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [122]
Methotrexate DM2TEOL Anterior urethra cancer Approved [123]
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Drug(s) Affected By Trefoil factor 1 (TFF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [124]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [91]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [125]
Quercetin DM3NC4M Obesity 5B81 Approved [126]
Estrone DM5T6US Acne vulgaris ED80 Approved [127]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [128]
Testosterone DM7HUNW Hot flushes GA30 Approved [129]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [130]
Exemestane DM9HPW3 Hormonally-responsive breast cancer 2C60-2C65 Approved [131]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [52]
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Drug(s) Affected By Potassium voltage-gated channel subfamily A member 3 (KCNA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [132]
Fluoxetine DM3PD2C Bipolar depression Approved [133]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [54]
Econazole DMFSWGH Cutaneous candidiasis 1F23.14 Approved [132]
Nifedipine DMSVOZT Angina pectoris BA40 Approved [133]
Arsenic DMTL2Y1 N. A. N. A. Approved [134]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [135]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [136]
Sulforaphane DMQY3L0 Skin disease EA00-EM0Z Investigative [137]
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Drug(s) Affected By Interleukin-10 (IL10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [138]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [139]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [140]
Methotrexate DM2TEOL Anterior urethra cancer Approved [141]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [142]
Quercetin DM3NC4M Obesity 5B81 Approved [143]
Bisoprolol DM3UZ95 Hypertension BA00-BA04 Approved [144]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [145]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [146]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [87]
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Drug(s) Affected By G1/S-specific cyclin-D1 (CCND1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [147]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [148]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [149]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [150]
Gefitinib DM15F0X Colon adenocarcinoma Approved [151]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [152]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [153]
Selenium DM25CGV N. A. N. A. Approved [154]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [120]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [155]
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Drug(s) Affected By Potassium voltage-gated channel subfamily H member 2 (KCNH2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Metoclopramide DMFA5MY Nausea MD90 Approved [156]
Quinidine DMLPICK N. A. N. A. Approved [157]
Verapamil DMA7PEW Angina pectoris BA40 Approved [158]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [159]
Clarithromycin DM4M1SG Acute maxillary sinusitis Approved [159]
Disopyramide DM5SYZP Long QT syndrome BC65.0 Approved [160]
Propranolol DM79NTF Angina pectoris BA40 Approved [161]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [162]
Dofetilide DMPN1TW Sinus rhythm disorder BC9Y Approved [163]
Flecainide DMSQDLE Tachyarrhythmias BC71 Approved [159]
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Drug(s) Affected By E3 ubiquitin-protein ligase SIAH1 (SIAH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [83]
Selenium DM25CGV N. A. N. A. Approved [154]
Quercetin DM3NC4M Obesity 5B81 Approved [164]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [88]
Leflunomide DMR8ONJ Arthritis FA20 Approved [95]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [53]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [48]
Menthol DMG2KW7 Back pain ME84.Z Approved [165]
Hexachlorophene DMLKSE0 Bacterial infection 1A00-1C4Z Approved [166]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [167]
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Drug(s) Affected By Chromaffin granule amine transporter (SLC18A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [169]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [170]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [136]
SEROTONIN DMOFCRY Discovery agent N.A. Investigative [171]
Drug(s) Affected By Secretogranin-1 (CHGB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [118]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [48]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [58]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [172]
Urethane DM7NSI0 N. A. N. A. Phase 4 [173]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [174]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [136]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [175]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [176]
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Drug(s) Affected By N-alpha-acetyltransferase 20 (NAA20)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [177]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [178]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [55]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [179]
Arsenic DMTL2Y1 N. A. N. A. Approved [134]
Dapsone DM4LT8A Acne vulgaris ED80 Approved [6]
Procainamide DMNMXR8 Ventricular arrhythmias BC71 Approved [6]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [180]
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Drug(s) Affected By Synaptic vesicular amine transporter (SLC18A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Norepinephrine DMOUC09 Alopecia ED70 Approved [181]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [181]
Methamphetamine DMPM4SK Anxiety Approved [182]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [183]
Haloperidol DM96SE0 Delirium Approved [183]
Leflunomide DMR8ONJ Arthritis FA20 Approved [95]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [54]
Dextroamphetamine DMMIHVP Attention deficit hyperactivity disorder 6A05.Z Approved [183]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [184]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [185]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Peptidyl-glycine alpha-amidating monooxygenase (PAM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [154]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [48]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [179]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [186]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [91]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [187]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [61]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [172]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Carboxypeptidase E (CPE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [188]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [189]
Panobinostat DM58WKG Chronic graft versus host disease Approved [45]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [190]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [177]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [48]
Ethanol DMDRQZU Chronic pain MG30 Approved [191]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [179]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [167]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [186]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Synaptic vesicle amine transporter (SLC18A2) TTNZRI3 VMAT2_HUMAN Blocker [3]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Breast cancer resistance protein (ABCG2) DTI7UX6 ABCG2_HUMAN Substrate [4]
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [5]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Adenylate cyclase type 1 (ADCY1) OTSLLFZO ADCY1_HUMAN Drug Response [6]
Aldo-keto reductase family 1 member B10 (AKR1B10) OTOA4HTH AK1BA_HUMAN Gene/Protein Processing [7]
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Gene/Protein Processing [8]
Baculoviral IAP repeat-containing protein 5 (BIRC5) OTILXZYL BIRC5_HUMAN Protein Interaction/Cellular Processes [9]
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 (GCNT3) OTQ9ALTR GCNT3_HUMAN Gene/Protein Processing [7]
Bile salt export pump (ABCB11) OTRU7THO ABCBB_HUMAN Gene/Protein Processing [10]
Carboxypeptidase E (CPE) OTXNTV79 CBPE_HUMAN Drug Response [6]
Chromaffin granule amine transporter (SLC18A1) OT01OALS VMAT1_HUMAN Drug Response [6]
Cytochrome P450 3A4 (CYP3A4) OTQGYY83 CP3A4_HUMAN Gene/Protein Processing [11]
Cytochrome P450 3A5 (CYP3A5) OTSXFBXB CP3A5_HUMAN Gene/Protein Processing [12]

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