General Information of Drug (ID: DMI6HUW)

Drug Name
Terbinafine Drug Info
Synonyms
Bramazil; Lamasil; TerbiFoam; Terbina; Lamisil AT; Lamisil Tablet; Ternbinafine HCl; Lamasil (TN); Lamisil (TN); SF 86-327; Terbisil (TN); Zabel (TN); SF-86-327; Terbinafine (USAN/INN); Terbinafine [USAN:BAN:INN]; Lamisil, Terbinex, Corbinal, Zabel, Terbinafine; Terbinafine, SF-86-327, Lamisil, TBNF; (2E)-N,6,6-trimethyl-N-(1-naphthylmethyl)-2-hepten-4-yn-1-amine; (2E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine; (E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine; (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalene methanamine; (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamine; (E)-N-(6,6-dimethyl-2-heptenynyl)-N-methyl-1-naphthalenementhamin hydrochloride
Indication
Disease Entry ICD 11 Status REF
Fungal infection 1F29-1F2F Approved [1]
Tinea corporis 1F28.Y Approved [2]
Tinea cruris 1F28.3 Approved [2]
Tinea versicolor 1F2D.0 Approved [2]
Onychomycosis EE12.1 Phase 2 [3]
Tinea pedis 1F28.2 Investigative [2]
Therapeutic Class
Antifungal Agents
Cross-matching ID
PubChem CID
1549008
ChEBI ID
CHEBI:9448
CAS Number
CAS 91161-71-6
TTD Drug ID
DMI6HUW
INTEDE Drug ID
DR1557
ACDINA Drug ID
D00663

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Butenafine DMOJ4ZI Dermatologic infection 1F28 Approved [4]
Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [14]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [15]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [16]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [17]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [18]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [19]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [20]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [21]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [15]
Verapamil DMA7PEW Angina pectoris BA40 Approved [5]
Eplerenone DMF0NQR Heart failure BD10-BD13 Approved [53]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [54]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [55]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [56]
Proguanil DMBL79I Malaria 1F40-1F45 Approved [57]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [57]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [58]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [59]
Capsaicin DMGMF6V Back pain ME84.Z Approved [60]
Axitinib DMGVH6N Renal cell carcinoma 2C90 Approved [61]
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Drug(s) Metabolized By Cytochrome P450 1A2 (CYP1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [22]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [23]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [24]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [25]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [26]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [27]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [20]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [28]
Verapamil DMA7PEW Angina pectoris BA40 Approved [29]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [30]
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Drug(s) Metabolized By Cytochrome P450 2C8 (CYP2C8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [22]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [31]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [31]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [32]
Verapamil DMA7PEW Angina pectoris BA40 Approved [33]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [34]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [35]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [31]
Mycophenolate mofetil DMPQAGE Hepatosplenic T-cell lymphoma Approved [36]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [37]
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Drug(s) Metabolized By Cytochrome P450 2C9 (CYP2C9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Progesterone DMUY35B Amenorrhea GA20.0 Approved [38]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [39]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [40]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [32]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [41]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [32]
Verapamil DMA7PEW Angina pectoris BA40 Approved [42]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [43]
Estrone DM5T6US Acne vulgaris ED80 Approved [44]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [45]
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Drug(s) Metabolized By Mephenytoin 4-hydroxylase (CYP2C19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [46]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [38]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [47]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [48]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [32]
Verapamil DMA7PEW Angina pectoris BA40 Approved [49]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [50]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [45]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [51]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [37]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [5]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [52]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [5]
Diazepam DM08E9O Alcohol withdrawal Approved [5]
Dapsone DM4LT8A Acne vulgaris ED80 Approved [5]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [5]
Nateglinide DMLK2QH Diabetic complication 5A2Y Approved [5]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [5]
Ketobemidone DMM3L6Z Pain MG30-MG3Z Approved [5]
Irbesartan DMTP1DC Diabetic kidney disease GB61.Z Approved [5]
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Drug(s) Affected By Cytochrome P450 2D6 (CYP2D6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [62]
Paliperidone DM7NPJS Psychotic disorder 6A20-6A25 Approved [63]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [64]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [65]
Oxatomide DM1F42Z Hay fever CA08.00 Approved [66]
Cinacalcet DMCX0K3 Hyperparathyroidism 5A51 Approved [67]
Capsaicin DMGMF6V Back pain ME84.Z Approved [68]
Pentamidine DMHZJCG African trypanosomiasis 1F51 Approved [57]
Quinidine DMLPICK N. A. N. A. Approved [69]
Buprenorphine DMPRI8G Opioid dependence 6C43.2Z Approved [70]
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Drug(s) Affected By Tumor necrosis factor (TNF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [71]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [72]
Fructose DM43AN2 Vomiting MD90 Approved [73]
Ketoprofen DMRKXPT Bursitis Approved [73]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [74]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [75]
Baclofen DM0QV1J Multiple sclerosis 8A40 Approved [76]
Gefitinib DM15F0X Colon adenocarcinoma Approved [77]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [78]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [79]
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Drug(s) Affected By Cytochrome P450 1A1 (CYP1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [80]
Riluzole DMECBWN Amyotrophic lateral sclerosis 8B60.0 Approved [8]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [81]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [82]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [83]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [84]
Ethacrynic acid DM60QMR Edema MG29 Approved [85]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [86]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [87]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [88]
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Drug(s) Affected By Interleukin-4 (IL4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [89]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [90]
Tolnaftate DM28MU7 Dermatophytosis 1F28.2 Approved [12]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [91]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [92]
Prednisone DM2HG4X Acute asthma CA23 Approved [93]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [94]
Methotrexate DM2TEOL Anterior urethra cancer Approved [95]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [96]
Cladribine DM3JDRP Hairy cell leukaemia 2A82.2 Approved [97]
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Drug(s) Affected By Interleukin-5 (IL5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [98]
Tolnaftate DM28MU7 Dermatophytosis 1F28.2 Approved [12]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [91]
Prednisone DM2HG4X Acute asthma CA23 Approved [99]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [100]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [101]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [102]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [104]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [105]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [106]
Quercetin DM3NC4M Obesity 5B81 Approved [107]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [108]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [109]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [110]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [111]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [112]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [113]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [114]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [115]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [116]
Selenium DM25CGV N. A. N. A. Approved [117]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [118]
Quercetin DM3NC4M Obesity 5B81 Approved [119]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [120]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [121]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [122]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [123]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [124]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [125]
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Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [126]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [127]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [128]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [129]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [130]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [131]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [132]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [133]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [134]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [132]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [135]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [136]
Gefitinib DM15F0X Colon adenocarcinoma Approved [77]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [79]
Selenium DM25CGV N. A. N. A. Approved [117]
Pentosan Polysulfate DM2HRKE Interstitial cystitis GC00.3 Approved [137]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [138]
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [140]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [141]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [142]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [143]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [144]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [75]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [145]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [146]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [147]
Gefitinib DM15F0X Colon adenocarcinoma Approved [148]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [149]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [151]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [143]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [152]
Paclitaxel DMLB81S Breast carcinoma Approved [153]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [154]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [142]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [73]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [155]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [75]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [145]
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Drug(s) Affected By Paxillin (PXN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [95]
Quercetin DM3NC4M Obesity 5B81 Approved [156]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [157]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [158]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [159]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [112]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [160]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [115]
Cholecalciferol DMGU74E Adult acute monocytic leukemia Approved [161]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [162]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [163]
Methotrexate DM2TEOL Anterior urethra cancer Approved [164]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [106]
Quercetin DM3NC4M Obesity 5B81 Approved [165]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [166]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [166]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [167]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [168]
Pamidronate DMB4AVP Bone Paget disease Approved [169]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [170]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [171]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [166]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [166]
Panobinostat DM58WKG Chronic graft versus host disease Approved [172]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [110]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [173]
Leflunomide DMR8ONJ Arthritis FA20 Approved [174]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [168]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [175]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [113]
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Drug(s) Affected By Focal adhesion kinase 1 (PTK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [146]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [176]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [177]
Quercetin DM3NC4M Obesity 5B81 Approved [165]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [178]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [179]
Testosterone DM7HUNW Hot flushes GA30 Approved [180]
Halothane DM80OZ5 Anaesthesia 9A78.6 Approved [181]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [182]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [183]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Metoclopramide DMFA5MY Nausea MD90 Approved [184]
Quinidine DMLPICK N. A. N. A. Approved [185]
Verapamil DMA7PEW Angina pectoris BA40 Approved [186]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [187]
Clarithromycin DM4M1SG Acute maxillary sinusitis Approved [187]
Disopyramide DM5SYZP Long QT syndrome BC65.0 Approved [188]
Propranolol DM79NTF Angina pectoris BA40 Approved [189]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [190]
Dofetilide DMPN1TW Sinus rhythm disorder BC9Y Approved [191]
Flecainide DMSQDLE Tachyarrhythmias BC71 Approved [187]
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Drug(s) Affected By Cytochrome P450 1B1 (CYP1B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [8]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [192]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [193]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [194]
Estrone DM5T6US Acne vulgaris ED80 Approved [195]
Melatonin DMKWFBT Depression 6A70-6A7Z Approved [196]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [197]
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [198]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [199]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [129]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [200]
Verapamil DMA7PEW Angina pectoris BA40 Approved [201]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [202]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [133]
Selenium DM25CGV N. A. N. A. Approved [203]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [204]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [205]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [206]
Quercetin DM3NC4M Obesity 5B81 Approved [107]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [207]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [208]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [209]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [159]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [210]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [211]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [212]
Indomethacin DMSC4A7 Bursitis Approved [213]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [214]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [215]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [216]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [217]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [218]
Allopurinol DMLPAOB Gout FA25 Approved [219]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [220]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [221]
Ticlopidine DMO946V Acute coronary syndrome BA41 Approved [222]
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [221]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [208]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [223]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [223]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [224]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [224]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [183]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [225]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [193]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [227]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [193]
DNCB DMDTVYC Immune System disease 4A01-4B41 Phase 2 [228]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [229]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Candida Squalene epoxidase (Candi ERG1) TTM9XSU ERG1_CANAL Modulator [4]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Substrate [5]
Cytochrome P450 2C9 (CYP2C9) DE5IED8 CP2C9_HUMAN Substrate [5]
Mephenytoin 4-hydroxylase (CYP2C19) DEGTFWK CP2CJ_HUMAN Substrate [6]
Cytochrome P450 1A2 (CYP1A2) DEJGDUW CP1A2_HUMAN Substrate [6]
Cytochrome P450 2C8 (CYP2C8) DES5XRU CP2C8_HUMAN Substrate [5]
Prostaglandin G/H synthase 1 (COX-1) DE073H6 PGH1_HUMAN Substrate [5]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
72 kDa type IV collagenase (MMP2) OT5NIWA2 MMP2_HUMAN Gene/Protein Processing [7]
Cytochrome P450 1A1 (CYP1A1) OTE4EFH8 CP1A1_HUMAN Gene/Protein Processing [8]
Cytochrome P450 1B1 (CYP1B1) OTYXFLSD CP1B1_HUMAN Gene/Protein Processing [8]
Cytochrome P450 2D6 (CYP2D6) OTZJC802 CP2D6_HUMAN Gene/Protein Processing [9]
Cytochrome P450 3A4 (CYP3A4) OTQGYY83 CP3A4_HUMAN Gene/Protein Processing [10]
Focal adhesion kinase 1 (PTK2) OT3Q1JDY FAK1_HUMAN Post-Translational Modifications [7]
HLA class I histocompatibility antigen, A alpha chain (HLA-A) OTAH14LU HLAA_HUMAN Drug Response [11]
Interleukin-4 (IL4) OTOXBWAU IL4_HUMAN Gene/Protein Processing [12]
Interleukin-5 (IL5) OTAFPSCO IL5_HUMAN Gene/Protein Processing [12]
Interleukin-8 (CXCL8) OTS7T5VH IL8_HUMAN Gene/Protein Processing [13]

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122 Temporal changes in gene expression in the skin of patients treated with isotretinoin provide insight into its mechanism of action. Dermatoendocrinol. 2009 May;1(3):177-87.
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126 Monomeric and oligomeric flavanols maintain the endogenous glucocorticoid response in human macrophages in pro-oxidant conditions in vitro. Chem Biol Interact. 2018 Aug 1;291:237-244.
127 Nicotine up-regulates IL-8 expression in human gingival epithelial cells following stimulation with IL-1 or P. gingivalis lipopolysaccharide via nicotinic acetylcholine receptor signalling. Arch Oral Biol. 2012 May;57(5):483-90. doi: 10.1016/j.archoralbio.2011.10.007. Epub 2011 Nov 25.
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129 Calcium pantothenate modulates gene expression in proliferating human dermal fibroblasts. Exp Dermatol. 2009 Nov;18(11):969-78. doi: 10.1111/j.1600-0625.2009.00884.x. Epub 2009 Apr 8.
130 Nitrogen mustard prevents transport of Fra-1 into the nucleus to promote c-Fos- and FosB-dependent IL-8 induction in injured mouse epidermis. Toxicol Lett. 2020 Feb 1;319:256-263. doi: 10.1016/j.toxlet.2019.10.006. Epub 2019 Oct 19.
131 ERE-independent ERalpha target genes differentially expressed in human breast tumors. Mol Cell Endocrinol. 2005 Dec 21;245(1-2):53-9. doi: 10.1016/j.mce.2005.10.003. Epub 2005 Nov 17.
132 An in vitro coculture system of human peripheral blood mononuclear cells with hepatocellular carcinoma-derived cells for predicting drug-induced liver injury. Arch Toxicol. 2021 Jan;95(1):149-168. doi: 10.1007/s00204-020-02882-4. Epub 2020 Aug 20.
133 Gypenosides protect retinal pigment epithelium cells from oxidative stress. Food Chem Toxicol. 2018 Feb;112:76-85.
134 Nitric oxide synthase inhibitors attenuate ozone-induced airway inflammation in guinea pigs. Possible role of interleukin-8. Am J Respir Crit Care Med. 2000 Jan;161(1):249-56. doi: 10.1164/ajrccm.161.1.9804096.
135 Cannabidiol Effectively Promoted Cell Death in Bladder Cancer and the Improved Intravesical Adhesion Drugs Delivery Strategy Could Be Better Used for Treatment. Pharmaceutics. 2021 Sep 7;13(9):1415. doi: 10.3390/pharmaceutics13091415.
136 Arsenite and cadmium promote the development of mammary tumors. Carcinogenesis. 2020 Jul 14;41(7):1005-1014. doi: 10.1093/carcin/bgz176.
137 Pentosan polysulfate decreases proliferation and extracellular matrix deposition by vascular smooth muscle cells isolated from failed hemodialysis access grafts. Clin Nephrol. 2000 Aug;54(2):121-7.
138 Investigation of molecular mechanisms underlying the antiproliferative effects of colchicine against PC3 prostate cancer cells. Toxicol In Vitro. 2021 Jun;73:105138. doi: 10.1016/j.tiv.2021.105138. Epub 2021 Mar 6.
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