General Information of Drug (ID: DMBHO9Y)

Drug Name
Adinazolam Drug Info
Synonyms
Adinazolamum; Deracyn; Adinazolam [USAN]; U 41123; Adinazolamum [INN-Latin]; Deracyn (TN); U 41,123;U-41123; Adinazolam (USAN/INN); Adinazolam [USAN:BAN:INN]; 1-(8-chloro-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-1-yl)-N,N-dimethylmethanamine; 8-Chloro-1-((dimethylamino)methyl)-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine; 8-chloro-1-[(dimethylamino)methyl]-6-phenyl-4h-s-triazolo[4,3-a][1,4]benzodiazepine
Indication
Disease Entry ICD 11 Status REF
Anxiety disorder 6B00-6B0Z Approved [1]
Therapeutic Class
Antidepressants
Cross-matching ID
PubChem CID
37632
ChEBI ID
CHEBI:251412
CAS Number
CAS 37115-32-5
TTD Drug ID
DMBHO9Y
INTEDE Drug ID
DR0048

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DME
DOT
Drug Status:
Approved Drug(s)
Drug(s) Targeting Translocator protein (TSPO)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Diazepam DM08E9O Alcohol withdrawal Approved [4]
Flunitrazepam DMGR5Z3 Insomnia 7A00-7A0Z Approved [5]
Oxazepam DMXNZM4 Alcohol withdrawal delirium Approved [6]
Midazolam DMXOELT Agitation 6A70.3 Approved [7]
Temazepam DM02A65 Insomnia 7A00-7A0Z Approved [7]
Flumazenil DMPCG2L Benzodiazepine overdose PC91 Approved [8]
Alprazolam DMC7XDN Anxiety Approved [5]
Clotiazepam DM59AZT Anxiety disorder 6B00-6B0Z Approved [9]
Quazepam DMY4D87 Insomnia 7A00-7A0Z Approved [7]
Eszopiclone DM8RZ9H Insomnia 7A00-7A0Z Approved [10]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [11]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [12]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [13]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [14]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [15]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [16]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [17]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [18]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [12]
Verapamil DMA7PEW Angina pectoris BA40 Approved [19]
Eplerenone DMF0NQR Heart failure BD10-BD13 Approved [30]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [31]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [32]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [33]
Proguanil DMBL79I Malaria 1F40-1F45 Approved [34]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [34]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [35]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [36]
Capsaicin DMGMF6V Back pain ME84.Z Approved [37]
Axitinib DMGVH6N Renal cell carcinoma 2C90 Approved [38]
⏷ Show the Full List of 20 Drug(s)
Drug(s) Metabolized By Mephenytoin 4-hydroxylase (CYP2C19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [20]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [21]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [22]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [23]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [24]
Verapamil DMA7PEW Angina pectoris BA40 Approved [25]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [26]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [27]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [28]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [29]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome P450 2C19 (CYP2C19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [31]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [39]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [33]
Chloramphenicol DMFXEWT Bacterial infection 1A00-1C4Z Approved [40]
Capsaicin DMGMF6V Back pain ME84.Z Approved [41]
Pentamidine DMHZJCG African trypanosomiasis 1F51 Approved [34]
Stiripentol DMMSDOY Dravet syndrome 8A61.11 Approved [42]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [34]
Desipramine DMT2FDC Attention deficit hyperactivity disorder 6A05.Z Approved [39]
Amitriptyline DMK7F9S Depression 6A70-6A7Z Approved [43]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Translocator protein (TSPO) TTPTXIN TSPO_HUMAN Agonist [2]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Substrate [3]
Mephenytoin 4-hydroxylase (CYP2C19) DEGTFWK CP2CJ_HUMAN Substrate [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Cytochrome P450 2C19 (CYP2C19) OTFMJYYE CP2CJ_HUMAN Biotransformations [3]
Cytochrome P450 3A4 (CYP3A4) OTQGYY83 CP3A4_HUMAN Biotransformations [3]

References

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