Details of the Drug Combination

General Information of Drug Combination (ID: DC82QEH)

• Drug Combination Name: Diethylstilbestrol + Panobinostat
• Indication: Diffuse intrinsic pontine glioma; Status: Investigative [1]
• Component Drugs:
  Diethylstilbestrol (DMN3UXQ): Small molecular drug
  Panobinostat (DM58WKG): Small molecular drug
• High-throughput Screening Result:
  Testing Cell Line: DIPG25
  Zero Interaction Potency (ZIP) Score: 6.523
  Bliss Independence Score: 6.156
  Loewe Additivity Score: 3.555
  LHighest Single Agent (HSA) Score: 3.147

Molecular Interaction Atlas of This Drug Combination

Indication(s) of Diethylstilbestrol

Disease Entry	ICD 11	Status	REF
Gonorrheal vaginitis	GA02	Approved	[2]

Diethylstilbestrol Interacts with 1 DTT Molecule(s)

DTT Name	DTT ID	UniProt ID	Mode of Action	REF
Estrogen receptor (ESR)	TTZAYWL	ESR1_HUMAN	Agonist	[14]

Diethylstilbestrol Interacts with 1 DTP Molecule(s)

DTP Name	DTP ID	UniProt ID	Mode of Action	REF
P-glycoprotein 1 (ABCB1)	DTUGYRD	MDR1_HUMAN	Substrate	[15]

Diethylstilbestrol Interacts with 2 DME Molecule(s)

DME Name	DME ID	UniProt ID	Mode of Action	REF
Cytochrome P450 3A4 (CYP3A4)	DE4LYSA	CP3A4_HUMAN	Metabolism	[16]
Cytochrome P450 2C8 (CYP2C8)	DES5XRU	CP2C8_HUMAN	Metabolism	[17]

Diethylstilbestrol Interacts with 614 DOT Molecule(s)

DOT Name	DOT ID	UniProt ID	Mode of Action	REF
Cytochrome P450 3A4 (CYP3A4)	OTQGYY83	CP3A4_HUMAN	Increases Expression	[18]
ATP-dependent translocase ABCB1 (ABCB1)	OTEJROBO	MDR1_HUMAN	Decreases Expression	[19]
Alpha-1-antichymotrypsin (SERPINA3)	OT9BP2S0	AACT_HUMAN	Increases Expression	[20]
Trefoil factor 1 (TFF1)	OTCYQH4F	TFF1_HUMAN	Increases Expression	[20]
Transforming growth factor beta-3 proprotein (TGFB3)	OT2LOUQ1	TGFB3_HUMAN	Increases Expression	[20]
Amine oxidase A (MAOA)	OT8NIWMQ	AOFA_HUMAN	Increases Expression	[20]
Glutathione S-transferase Mu 3 (GSTM3)	OTLA2WJT	GSTM3_HUMAN	Increases Expression	[21]
Cbp/p300-interacting transactivator 2 (CITED2)	OT812TV7	CITE2_HUMAN	Increases Expression	[21]
Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) (SLC6A14)	OTN51IPT	S6A14_HUMAN	Increases Expression	[21]
Cholesterol side-chain cleavage enzyme, mitochondrial (CYP11A1)	OT2NV3AN	CP11A_HUMAN	Decreases Expression	[22]
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 (HSD3B1)	OTNAZVKB	3BHS1_HUMAN	Decreases Expression	[22]
17-beta-hydroxysteroid dehydrogenase type 1 (HSD17B1)	OT6EBDHM	DHB1_HUMAN	Decreases Expression	[22]
Homeobox protein DLX-4 (DLX4)	OTLWVCN4	DLX4_HUMAN	Decreases Expression	[22]
5-hydroxymethyl-dUMP N-hydrolase (DNPH1)	OTEZVTI1	DNPH1_HUMAN	Increases Expression	[6]
Programmed cell death protein 6 (PDCD6)	OT2YA5M8	PDCD6_HUMAN	Increases Expression	[6]
Myc proto-oncogene protein (MYC)	OTPV5LUK	MYC_HUMAN	Increases Expression	[6]
Apolipoprotein E (APOE)	OTFOWL2H	APOE_HUMAN	Increases Expression	[6]
Calpain small subunit 1 (CAPNS1)	OT95EBBD	CPNS1_HUMAN	Increases Expression	[6]
Prothymosin alpha (PTMA)	OT2W4T1M	PTMA_HUMAN	Increases Expression	[6]
Tyrosine-protein kinase Lyn (LYN)	OTP686K2	LYN_HUMAN	Increases Expression	[6]
Tyrosine-protein kinase Fgr (FGR)	OTCUYU9F	FGR_HUMAN	Increases Expression	[6]
DNA polymerase alpha catalytic subunit (POLA1)	OT1WXFVY	DPOLA_HUMAN	Increases Expression	[6]
Clusterin (CLU)	OTQGG0JM	CLUS_HUMAN	Increases Expression	[6]
Ski oncogene (SKI)	OT4KJ8F6	SKI_HUMAN	Increases Expression	[6]
Glucosidase 2 subunit beta (PRKCSH)	OTJCQYUU	GLU2B_HUMAN	Increases Expression	[6]
Fos-related antigen 1 (FOSL1)	OT9YTYMB	FOSL1_HUMAN	Increases Expression	[6]
Nucleoside diphosphate kinase A (NME1)	OT0NELQ1	NDKA_HUMAN	Increases Expression	[6]
Insulin-like growth factor-binding protein 2 (IGFBP2)	OTG1P60E	IBP2_HUMAN	Increases Expression	[6]
Nucleoside diphosphate kinase B (NME2)	OTCYGLHV	NDKB_HUMAN	Increases Expression	[6]
Stromelysin-3 (MMP11)	OTRTXDBM	MMP11_HUMAN	Increases Expression	[6]
Integrin beta-7 (ITGB7)	OT33UUKU	ITB7_HUMAN	Increases Expression	[6]
Adenosine receptor A1 (ADORA1)	OTI7X39E	AA1R_HUMAN	Increases Expression	[6]
Cyclin-dependent kinases regulatory subunit 2 (CKS2)	OTPTMHIV	CKS2_HUMAN	Increases Expression	[6]
Replication protein A 14 kDa subunit (RPA3)	OT8JAQGL	RFA3_HUMAN	Increases Expression	[6]
DNA damage-inducible transcript 3 protein (DDIT3)	OTI8YKKE	DDIT3_HUMAN	Increases Expression	[6]
Small ribosomal subunit protein eS19 (RPS19)	OTBKGP48	RS19_HUMAN	Increases Expression	[6]
DNA mismatch repair protein Mlh1 (MLH1)	OTG5XDD8	MLH1_HUMAN	Increases Expression	[6]
Replication factor C subunit 5 (RFC5)	OTAD79RT	RFC5_HUMAN	Increases Expression	[6]
Signal transducer and activator of transcription 1-alpha/beta (STAT1)	OTLMBUZ6	STAT1_HUMAN	Increases Expression	[6]
Netrin receptor DCC (DCC)	OT2C1SHW	DCC_HUMAN	Increases Expression	[6]
Rap1 GTPase-activating protein 1 (RAP1GAP)	OTC31ONQ	RPGP1_HUMAN	Increases Expression	[6]
Fms-related tyrosine kinase 3 ligand (FLT3LG)	OTU0YGC4	FLT3L_HUMAN	Increases Expression	[6]
Adenosine 5'-monophosphoramidase HINT1 (HINT1)	OTQIR8LF	HINT1_HUMAN	Increases Expression	[6]
Cyclin-dependent kinase inhibitor 1C (CDKN1C)	OTASTJ3Q	CDN1C_HUMAN	Increases Expression	[6]
Protein Tob1 (TOB1)	OTNW949D	TOB1_HUMAN	Increases Expression	[6]
Tyrosine-protein kinase JAK3 (JAK3)	OTQ8QW2L	JAK3_HUMAN	Increases Expression	[6]
Cyclin-dependent kinases regulatory subunit 1 (CKS1B)	OTNUPLUJ	CKS1_HUMAN	Increases Expression	[6]
Small ribosomal subunit protein eS1 (RPS3A)	OTUEP7CL	RS3A_HUMAN	Increases Expression	[6]
Cyclin-dependent kinase 5 (CDK5)	OT1YAK9F	CDK5_HUMAN	Increases Expression	[6]
Dual specificity mitogen-activated protein kinase kinase 1 (MAP2K1)	OT4Y9NQI	MP2K1_HUMAN	Increases Expression	[6]
Activated CDC42 kinase 1 (TNK2)	OTRGG0T8	ACK1_HUMAN	Increases Expression	[6]
Epithelial discoidin domain-containing receptor 1 (DDR1)	OTYW1SH8	DDR1_HUMAN	Increases Expression	[6]
Adenylate cyclase type 1 (ADCY1)	OTSLLFZO	ADCY1_HUMAN	Increases Expression	[6]
Cell division cycle protein 20 homolog (CDC20)	OTCOEZRV	CDC20_HUMAN	Increases Expression	[6]
TNF receptor-associated factor 3 (TRAF3)	OT5TQBGV	TRAF3_HUMAN	Increases Expression	[6]
Frizzled-2 (FZD2)	OT952ML1	FZD2_HUMAN	Increases Expression	[6]
Cyclin-dependent kinase 10 (CDK10)	OTKP7TTR	CDK10_HUMAN	Increases Expression	[6]
Sulfotransferase 1E1 (SULT1E1)	OTGPJ517	ST1E1_HUMAN	Decreases Activity	[23]
Aromatase (CYP19A1)	OTZ6XF74	CP19A_HUMAN	Decreases Activity	[24]
Espin (ESPN)	OT7Z6LX2	ESPN_HUMAN	Increases Expression	[7]
Atypical chemokine receptor 2 (ACKR2)	OTWYY14H	ACKR2_HUMAN	Decreases Expression	[7]
Calpain-9 (CAPN9)	OTE4IU5U	CAN9_HUMAN	Increases Expression	[7]
ATP-binding cassette sub-family C member 3 (ABCC3)	OTC3IJV4	MRP3_HUMAN	Decreases Expression	[7]
E3 ubiquitin-protein ligase SIAH2 (SIAH2)	OTKED2XN	SIAH2_HUMAN	Increases Expression	[7]
Proline dehydrogenase 1, mitochondrial (PRODH)	OT7SQ1C7	PROD_HUMAN	Decreases Expression	[7]
Band 4.1-like protein 2 (EPB41L2)	OT6UABPM	E41L2_HUMAN	Increases Expression	[7]
Galanin receptor type 2 (GALR2)	OTNJBJC1	GALR2_HUMAN	Decreases Expression	[7]
Regulator of G-protein signaling 10 (RGS10)	OTQ8N1QH	RGS10_HUMAN	Increases Expression	[7]
Protein CBFA2T3 (CBFA2T3)	OTOJ10S1	MTG16_HUMAN	Increases Expression	[7]
Cartilage intermediate layer protein 1 (CILP)	OTKEY2NJ	CILP1_HUMAN	Increases Expression	[7]
Short-chain dehydrogenase/reductase 3 (DHRS3)	OTSK1DTP	DHRS3_HUMAN	Increases Expression	[7]
RasGAP-activating-like protein 1 (RASAL1)	OTAHUNN7	RASL1_HUMAN	Decreases Expression	[7]
EGF-containing fibulin-like extracellular matrix protein 2 (EFEMP2)	OT0I2B4J	FBLN4_HUMAN	Decreases Expression	[7]
Actin-associated protein FAM107A (FAM107A)	OTBG61YZ	F107A_HUMAN	Decreases Expression	[7]
Carbonic anhydrase 2 (CA2)	OTJRMUAG	CAH2_HUMAN	Increases Expression	[7]
Protransforming growth factor alpha (TGFA)	OTPD1LL9	TGFA_HUMAN	Increases Expression	[7]
Cytochrome P450 1A1 (CYP1A1)	OTE4EFH8	CP1A1_HUMAN	Decreases Expression	[7]
Thrombospondin-1 (THBS1)	OT0ECWK3	TSP1_HUMAN	Increases Expression	[7]
Beta-microseminoprotein (MSMB)	OTYORAJC	MSMB_HUMAN	Increases Expression	[7]
Amino acid transporter heavy chain SLC3A2 (SLC3A2)	OTBR33M9	4F2_HUMAN	Increases Expression	[7]
Hepatocyte growth factor receptor (MET)	OT7K55MU	MET_HUMAN	Increases Expression	[7]
Retinol-binding protein 1 (RBP1)	OTRP1MFC	RET1_HUMAN	Decreases Expression	[7]
Alkaline phosphatase, germ cell type (ALPG)	OTCIM29R	PPBN_HUMAN	Increases Expression	[7]
Serine/threonine-protein kinase pim-1 (PIM1)	OTWEKXTU	PIM1_HUMAN	Increases Expression	[7]
Aminopeptidase N (ANPEP)	OTP3WYFD	AMPN_HUMAN	Increases Expression	[7]
Folate receptor alpha (FOLR1)	OT0QZ0H6	FOLR1_HUMAN	Decreases Expression	[7]
CCAAT/enhancer-binding protein beta (CEBPB)	OTM9MQIA	CEBPB_HUMAN	Increases Expression	[7]
Diamine acetyltransferase 1 (SAT1)	OT52AU22	SAT1_HUMAN	Decreases Expression	[7]
Interleukin-4 receptor subunit alpha (IL4R)	OTTXOTCW	IL4RA_HUMAN	Increases Expression	[7]
Sodium- and chloride-dependent taurine transporter (SLC6A6)	OT67U7G3	SC6A6_HUMAN	Increases Expression	[7]
G protein-activated inward rectifier potassium channel 4 (KCNJ5)	OTA2MBIE	KCNJ5_HUMAN	Increases Expression	[7]
Nuclear receptor-interacting protein 1 (NRIP1)	OTIZOJQV	NRIP1_HUMAN	Increases Expression	[7]
ADP-ribosylation factor-like protein 4D (ARL4D)	OTG5I3KU	ARL4D_HUMAN	Increases Expression	[7]
CCAAT/enhancer-binding protein delta (CEBPD)	OTNBIPMY	CEBPD_HUMAN	Increases Expression	[7]
Homeobox protein MOX-1 (MEOX1)	OTJEMT2D	MEOX1_HUMAN	Decreases Expression	[7]
AF4/FMR2 family member 3 (AFF3)	OTR0705Z	AFF3_HUMAN	Increases Expression	[7]
Reelin (RELN)	OTLKMW1O	RELN_HUMAN	Increases Expression	[7]
ETS-related transcription factor Elf-3 (ELF3)	OTUTLEQO	ELF3_HUMAN	Increases Expression	[7]
Large neutral amino acids transporter small subunit 1 (SLC7A5)	OT2WPVXD	LAT1_HUMAN	Increases Expression	[7]
Keratin, type I cytoskeletal 17 (KRT17)	OT6Y1DPK	K1C17_HUMAN	Decreases Expression	[7]
Lactadherin (MFGE8)	OTQKE41R	MFGM_HUMAN	Decreases Expression	[7]
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 (FUT5)	OTOPGL9M	FUT5_HUMAN	Increases Expression	[7]
Frizzled-5 (FZD5)	OTXFFY56	FZD5_HUMAN	Increases Expression	[7]
Phakinin (BFSP2)	OT3QREFR	BFSP2_HUMAN	Increases Expression	[7]
Inositol-tetrakisphosphate 1-kinase (ITPK1)	OTP4PGL6	ITPK1_HUMAN	Increases Expression	[7]
Laminin subunit beta-3 (LAMB3)	OTFPU6W8	LAMB3_HUMAN	Increases Expression	[7]
Forkhead box protein D1 (FOXD1)	OT80PRHS	FOXD1_HUMAN	Increases Expression	[7]
Protein GREB1 (GREB1)	OTU6ZA26	GREB1_HUMAN	Increases Expression	[7]
Extracellular tyrosine-protein kinase PKDCC (PKDCC)	OTVXJR26	PKDCC_HUMAN	Increases Expression	[7]
Protein Flattop (CFAP126)	OT64F83F	FLTOP_HUMAN	Decreases Expression	[7]
Anoctamin-1 (ANO1)	OTSREUNI	ANO1_HUMAN	Increases Expression	[7]
Proline-rich protein 5-like (PRR5L)	OTQ1Z0OU	PRR5L_HUMAN	Increases Expression	[7]
Dynein axonemal intermediate chain 7 (DNAI7)	OTLXV3CP	DNAI7_HUMAN	Decreases Expression	[7]
Plexin domain-containing protein 2 (PLXDC2)	OTS1FUV6	PXDC2_HUMAN	Increases Expression	[7]
Isoaspartyl peptidase/L-asparaginase (ASRGL1)	OTNGNRBA	ASGL1_HUMAN	Increases Expression	[7]
Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4)	OT6WKC13	GALT4_HUMAN	Increases Expression	[7]
Ephexin-1 (NGEF)	OT9QUXJ3	NGEF_HUMAN	Decreases Expression	[7]
DEP domain-containing mTOR-interacting protein (DEPTOR)	OTCBP1BT	DPTOR_HUMAN	Increases Expression	[7]
CDK5 and ABL1 enzyme substrate 1 (CABLES1)	OTMN4XSX	CABL1_HUMAN	Increases Expression	[7]
Docking protein 4 (DOK4)	OTUEWLG8	DOK4_HUMAN	Increases Expression	[7]
Glycerophosphodiester phosphodiesterase domain-containing protein 5 (GDPD5)	OTUM65JL	GDPD5_HUMAN	Increases Expression	[7]
Glutathione-specific gamma-glutamylcyclotransferase 2 (CHAC2)	OTOGC15N	CHAC2_HUMAN	Increases Expression	[7]
Forkhead box protein J1 (FOXJ1)	OT7LLBZ7	FOXJ1_HUMAN	Decreases Expression	[7]
Tumor necrosis factor receptor superfamily member 25 (TNFRSF25)	OTVZ7I3A	TNR25_HUMAN	Decreases Expression	[7]
Endoplasmic reticulum resident protein 27 (ERP27)	OTVMGE2H	ERP27_HUMAN	Decreases Expression	[7]
Phosphoinositide-3-kinase-interacting protein 1 (PIK3IP1)	OTWE5G4T	P3IP1_HUMAN	Decreases Expression	[7]
Hyaluronan and proteoglycan link protein 3 (HAPLN3)	OTB853Z1	HPLN3_HUMAN	Decreases Expression	[7]
Protein Niban 2 (NIBAN2)	OTVDQSPI	NIBA2_HUMAN	Decreases Expression	[7]
Sphingosine 1-phosphate receptor 3 (S1PR3)	OTXBIYO8	S1PR3_HUMAN	Increases Expression	[7]
Neurturin (NRTN)	OT4PAKUY	NRTN_HUMAN	Increases Expression	[7]
Noelin (OLFM1)	OTOYPEWW	NOE1_HUMAN	Increases Expression	[7]
Melanophilin (MLPH)	OT7ADCXL	MELPH_HUMAN	Increases Expression	[7]
Fibronectin type III domain-containing protein 11 (FNDC11)	OT2IU0E9	FND11_HUMAN	Decreases Expression	[7]
RNA-binding protein 24 (RBM24)	OTQI1AR1	RBM24_HUMAN	Increases Expression	[7]
Potassium voltage-gated channel subfamily F member 1 (KCNF1)	OTEROKP4	KCNF1_HUMAN	Increases Expression	[7]
Transcription factor SOX-17 (SOX17)	OT9H4WWE	SOX17_HUMAN	Increases Expression	[7]
Prolyl hydroxylase EGLN3 (EGLN3)	OTXV3RYX	EGLN3_HUMAN	Increases Expression	[7]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (PLCB1)	OT9HYT7A	PLCB1_HUMAN	Increases Expression	[7]
Olfactomedin-like protein 3 (OLFML3)	OTDN45FN	OLFL3_HUMAN	Increases Expression	[7]
Ras-related protein Rab-20 (RAB20)	OTP9OOVS	RAB20_HUMAN	Decreases Expression	[7]
A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAMTS9)	OTV3Q0DS	ATS9_HUMAN	Increases Expression	[7]
Cilia- and flagella-associated protein 45 (CFAP45)	OT8I8ZHH	CFA45_HUMAN	Decreases Expression	[7]
Transcription factor HES-2 (HES2)	OTMWY2KV	HES2_HUMAN	Increases Expression	[7]
Lysosome-associated membrane glycoprotein 3 (LAMP3)	OTN0XL3W	LAMP3_HUMAN	Decreases Expression	[25]
Cytochrome P450 2B6 (CYP2B6)	OTOYO4S7	CP2B6_HUMAN	Increases Expression	[18]
Bile salt export pump (ABCB11)	OTRU7THO	ABCBB_HUMAN	Decreases Activity	[26]
Aldo-keto reductase family 1 member B10 (AKR1B10)	OTOA4HTH	AK1BA_HUMAN	Increases Expression	[27]
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 (GCNT3)	OTQ9ALTR	GCNT3_HUMAN	Increases Expression	[27]
Glutamate--cysteine ligase catalytic subunit (GCLC)	OTESDI4D	GSH1_HUMAN	Increases Expression	[27]
F-box only protein 30 (FBXO30)	OTD1P6LA	FBX30_HUMAN	Increases Expression	[27]
Cystine/glutamate transporter (SLC7A11)	OTKJ6PXW	XCT_HUMAN	Decreases Expression	[27]
Histone chaperone ASF1A (ASF1A)	OT4S44GP	ASF1A_HUMAN	Increases Expression	[27]
Serine/threonine-protein kinase Sgk1 (SGK1)	OT301T1U	SGK1_HUMAN	Increases Expression	[8]
Prostaglandin E synthase (PTGES)	OTB7YQFU	PTGES_HUMAN	Increases Expression	[8]
Carbonic anhydrase 12 (CA12)	OT6WNFU8	CAH12_HUMAN	Increases Expression	[8]
Tyrosine-protein kinase JAK2 (JAK2)	OTBIDOOR	JAK2_HUMAN	Increases Expression	[8]
monooxygenase MICAL2 (MICAL2)	OT04OQQJ	MICA2_HUMAN	Increases Expression	[8]
Serine protease 23 (PRSS23)	OT6DQAM1	PRS23_HUMAN	Increases Expression	[8]
Supervillin (SVIL)	OTWQQ1WK	SVIL_HUMAN	Increases Expression	[8]
Transcription factor AP-2-alpha (TFAP2A)	OTMYT3NK	AP2A_HUMAN	Decreases Expression	[8]
Proto-oncogene tyrosine-protein kinase receptor Ret (RET)	OTLU040A	RET_HUMAN	Increases Expression	[8]
Monoacylglycerol lipase ABHD2 (ABHD2)	OTCRUOCS	ABHD2_HUMAN	Increases Expression	[8]
Transcriptional activator Myb (MYB)	OTJH64IV	MYB_HUMAN	Increases Expression	[8]
Myb-related protein A (MYBL1)	OTBJMC2P	MYBA_HUMAN	Increases Expression	[8]
Tissue factor pathway inhibitor (TFPI)	OTA0FX16	TFPI1_HUMAN	Decreases Expression	[8]
Delta-aminolevulinic acid dehydratase (ALAD)	OTHM9GSH	HEM2_HUMAN	Decreases Expression	[8]
Amphiregulin (AREG)	OTJFOR67	AREG_HUMAN	Increases Expression	[8]
CD44 antigen (CD44)	OT9TTJ41	CD44_HUMAN	Increases Expression	[8]
Ephrin-A1 (EFNA1)	OTU2NUA2	EFNA1_HUMAN	Decreases Expression	[8]
G1/S-specific cyclin-D1 (CCND1)	OT8HPTKJ	CCND1_HUMAN	Increases Expression	[8]
Stromal cell-derived factor 1 (CXCL12)	OT2QX5LL	SDF1_HUMAN	Increases Expression	[8]
Ephrin type-A receptor 4 (EPHA4)	OT3AMK0C	EPHA4_HUMAN	Decreases Expression	[8]
Single-stranded DNA-binding protein 2 (SSBP2)	OTYG1G80	SSBP2_HUMAN	Decreases Expression	[8]
DNA-binding protein inhibitor ID-3 (ID3)	OTUULW5Z	ID3_HUMAN	Decreases Expression	[8]
Urokinase plasminogen activator surface receptor (PLAUR)	OTIRKKEQ	UPAR_HUMAN	Increases Expression	[8]
Forkhead box protein C1 (FOXC1)	OTOWZGYO	FOXC1_HUMAN	Increases Expression	[8]
Kynureninase (KYNU)	OTINL2RE	KYNU_HUMAN	Decreases Expression	[8]
Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3)	OTXGJ8N1	P55G_HUMAN	Decreases Expression	[8]
Dual specificity tyrosine-phosphorylation-regulated kinase 2 (DYRK2)	OTMDVWPS	DYRK2_HUMAN	Decreases Expression	[8]
Transcription factor AP-2 gamma (TFAP2C)	OTUDIW05	AP2C_HUMAN	Increases Expression	[8]
Serine/threonine-protein kinase Sgk3 (SGK3)	OTQ6QO99	SGK3_HUMAN	Increases Expression	[8]
Inactive rhomboid protein 1 (RHBDF1)	OTCQ7UDS	RHDF1_HUMAN	Decreases Expression	[8]
Calmin (CLMN)	OT7U5J3T	CLMN_HUMAN	Decreases Expression	[8]
Pleckstrin homology domain-containing family F member 2 (PLEKHF2)	OTBGDG8C	PKHF2_HUMAN	Decreases Expression	[8]
Spermine oxidase (SMOX)	OT11E62Y	SMOX_HUMAN	Increases Expression	[8]
Nicotinamide riboside kinase 1 (NMRK1)	OT0STQLV	NRK1_HUMAN	Increases Expression	[8]
Rap guanine nucleotide exchange factor-like 1 (RAPGEFL1)	OTYKE9ZM	RPGFL_HUMAN	Increases Expression	[8]
RNA 3'-terminal phosphate cyclase-like protein (RCL1)	OT7O00YX	RCL1_HUMAN	Increases Expression	[8]
Diphosphoinositol polyphosphate phosphohydrolase NUDT4B (NUDT4)	OTA6ICI2	NUD4B_HUMAN	Increases Expression	[10]
CBY1-interacting BAR domain-containing protein 1 (CIBAR1)	OTQFX76P	CBAR1_HUMAN	Decreases Expression	[10]
Protein FAM234B (FAM234B)	OTKMUX0R	F234B_HUMAN	Increases Expression	[10]
Protein strawberry notch homolog 1 (SBNO1)	OTNX3RL0	SBNO1_HUMAN	Decreases Expression	[10]
Cytosolic acyl coenzyme A thioester hydrolase (ACOT7)	OT7C68YV	BACH_HUMAN	Decreases Expression	[10]
HCLS1-associated protein X-1 (HAX1)	OTOJWV3F	HAX1_HUMAN	Decreases Expression	[10]
Receptor-binding cancer antigen expressed on SiSo cells (EBAG9)	OTTQLQCP	RCAS1_HUMAN	Decreases Expression	[10]
ATP-dependent RNA helicase DDX3X (DDX3X)	OTDO4TRX	DDX3X_HUMAN	Increases Expression	[10]
Stearoyl-CoA desaturase (SCD)	OTB1073G	SCD_HUMAN	Increases Expression	[10]
TRAF-type zinc finger domain-containing protein 1 (TRAFD1)	OT7AU2R3	TRAD1_HUMAN	Decreases Expression	[10]
Chromodomain-helicase-DNA-binding protein 1 (CHD1)	OT9R9G0H	CHD1_HUMAN	Decreases Expression	[10]
Transcription elongation regulator 1 (TCERG1)	OTH1LCGH	TCRG1_HUMAN	Increases Expression	[10]
Ras-related protein M-Ras (MRAS)	OTNCVCQW	RASM_HUMAN	Increases Expression	[10]
Glutathione S-transferase 3, mitochondrial (MGST3)	OTYK80JA	MGST3_HUMAN	Decreases Expression	[10]
Peripheral plasma membrane protein CASK (CASK)	OT8EF7ZF	CSKP_HUMAN	Affects Expression	[10]
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (AGPAT2)	OT5I4Y9K	PLCB_HUMAN	Increases Expression	[10]
Mothers against decapentaplegic homolog 9 (SMAD9)	OTK4M1H8	SMAD9_HUMAN	Decreases Expression	[10]
Prefoldin subunit 6 (PFDN6)	OTI8IPNC	PFD6_HUMAN	Decreases Expression	[10]
Monocarboxylate transporter 5 (SLC16A4)	OT1YXBKC	MOT5_HUMAN	Increases Expression	[10]
Cytochrome P450 26A1 (CYP26A1)	OTL1DFWV	CP26A_HUMAN	Increases Expression	[28]
Eukaryotic translation elongation factor 1 epsilon-1 (EEF1E1)	OTRA6XOB	MCA3_HUMAN	Decreases Expression	[10]
Pleiotropic regulator 1 (PLRG1)	OTIVZ5LL	PLRG1_HUMAN	Decreases Expression	[10]
Probable 18S rRNA (BUD23)	OTJS7VU3	BUD23_HUMAN	Decreases Expression	[10]
E3 ubiquitin-protein ligase MARCHF6 (MARCHF6)	OTBTA03N	MARH6_HUMAN	Increases Expression	[10]
Vinexin (SORBS3)	OTVEUODC	VINEX_HUMAN	Increases Expression	[10]
Sorting nexin-2 (SNX2)	OT889MQA	SNX2_HUMAN	Decreases Expression	[10]
Polyglutamine-binding protein 1 (PQBP1)	OTXCBEAH	PQBP1_HUMAN	Decreases Expression	[10]
Ribonuclease H1 (RNASEH1)	OTT7L25X	RNH1_HUMAN	Decreases Expression	[10]
Vesicle-trafficking protein SEC22b (SEC22B)	OTERD9S1	SC22B_HUMAN	Increases Expression	[10]
Erlin-1 (ERLIN1)	OTUOOODY	ERLN1_HUMAN	Decreases Expression	[10]
Serine/arginine-rich splicing factor 10 (SRSF10)	OTY6IJ11	SRS10_HUMAN	Decreases Expression	[10]
Claudin-11 (CLDN11)	OTNN6UTL	CLD11_HUMAN	Increases Expression	[10]
PR domain zinc finger protein 1 (PRDM1)	OTQLSVBS	PRDM1_HUMAN	Decreases Expression	[10]
Nuclear pore complex protein Nup155 (NUP155)	OTIIAH4E	NU155_HUMAN	Increases Expression	[10]
Pre-mRNA-splicing factor SPF27 (BCAS2)	OTRMF2WY	SPF27_HUMAN	Decreases Expression	[10]
DnaJ homolog subfamily C member 8 (DNAJC8)	OTBE4I4X	DNJC8_HUMAN	Decreases Expression	[10]
Stanniocalcin-2 (STC2)	OT86YP8G	STC2_HUMAN	Decreases Expression	[10]
Metastasis-associated protein MTA2 (MTA2)	OTCCYIQJ	MTA2_HUMAN	Increases Expression	[10]
Erlin-2 (ERLIN2)	OT551BVG	ERLN2_HUMAN	Decreases Expression	[10]
F-box only protein 21 (FBXO21)	OTM8L5VY	FBX21_HUMAN	Increases Expression	[10]
NADH dehydrogenase 1 alpha subcomplex subunit 10, mitochondrial (NDUFA10)	OTBURQ3A	NDUAA_HUMAN	Decreases Expression	[10]
Importin-7 (IPO7)	OTDFMQ00	IPO7_HUMAN	Increases Expression	[10]
GDH/6PGL endoplasmic bifunctional protein (H6PD)	OTO7TNDD	G6PE_HUMAN	Increases Expression	[10]
Mitochondrial pyruvate carrier 2 (MPC2)	OT0GHXGG	MPC2_HUMAN	Decreases Expression	[10]
STAM-binding protein (STAMBP)	OTOT2OXM	STABP_HUMAN	Decreases Expression	[10]
Renin (REN)	OT52GZR2	RENI_HUMAN	Increases Activity	[29]
Cystatin-A (CSTA)	OT1K68KE	CYTA_HUMAN	Affects Expression	[30]
Prolactin (PRL)	OTWFQGX7	PRL_HUMAN	Increases Secretion	[31]
Fibronectin (FN1)	OTB5ZN4Q	FINC_HUMAN	Decreases Expression	[10]
Estrogen receptor (ESR1)	OTKLU61J	ESR1_HUMAN	Increases Expression	[32]
Sex hormone-binding globulin (SHBG)	OTPWU5IW	SHBG_HUMAN	Affects Binding	[33]
Cellular tumor antigen p53 (TP53)	OTIE1VH3	P53_HUMAN	Decreases Expression	[30]
Guanine nucleotide-binding protein G(i) subunit alpha-2 (GNAI2)	OTTLGRGH	GNAI2_HUMAN	Decreases Expression	[10]
Sodium/potassium-transporting ATPase subunit beta-1 (ATP1B1)	OTTO6ZP4	AT1B1_HUMAN	Increases Expression	[10]
Lupus La protein (SSB)	OTCCTPBR	LA_HUMAN	Decreases Expression	[10]
Progesterone receptor (PGR)	OT0FZ3QE	PRGR_HUMAN	Increases Expression	[34]
Prostate-specific antigen (KLK3)	OTFGSBFJ	KLK3_HUMAN	Decreases Expression	[35]
Cathepsin B (CTSB)	OTP9G5QB	CATB_HUMAN	Increases Activity	[36]
Tropomyosin beta chain (TPM2)	OTA1L0P8	TPM2_HUMAN	Decreases Expression	[10]
Porphobilinogen deaminase (HMBS)	OT3P47DC	HEM3_HUMAN	Decreases Expression	[10]
Steryl-sulfatase (STS)	OTXTJQPC	STS_HUMAN	Decreases Activity	[37]
Gamma-enolase (ENO2)	OTRODL0T	ENOG_HUMAN	Decreases Expression	[12]
Trafficking protein particle complex subunit 2 (TRAPPC2)	OTWL5H45	TPC2A_HUMAN	Increases Expression	[10]
Protein POLR1D, isoform 2 (POLR1D)	OTOCZQNA	RPC22_HUMAN	Decreases Expression	[10]
Adrenodoxin, mitochondrial (FDX1)	OT7I3DN0	ADX_HUMAN	Increases Expression	[10]
Serglycin (SRGN)	OTFAVSX0	SRGN_HUMAN	Increases Expression	[10]
Androgen receptor (AR)	OTUBKAZZ	ANDR_HUMAN	Decreases Activity	[38]
Osteopontin (SPP1)	OTJGC23Y	OSTP_HUMAN	Decreases Expression	[10]
COUP transcription factor 1 (NR2F1)	OTGWZWYL	COT1_HUMAN	Increases Expression	[10]
S-formylglutathione hydrolase (ESD)	OTUSIBPS	ESTD_HUMAN	Decreases Expression	[10]
Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1)	OTA675TJ	GTR1_HUMAN	Decreases Activity	[39]
Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2)	OTPG0K7E	IMDH2_HUMAN	Decreases Expression	[10]
Protein disulfide-isomerase A4 (PDIA4)	OTVFUJ13	PDIA4_HUMAN	Increases Expression	[10]
Tissue factor (F3)	OT3MSU3B	TF_HUMAN	Increases Expression	[10]
Interferon gamma receptor 1 (IFNGR1)	OTCTQBWW	INGR1_HUMAN	Increases Expression	[10]
Beta-1,4-galactosyltransferase 1 (B4GALT1)	OTBCXEK7	B4GT1_HUMAN	Increases Expression	[40]
Cyclic AMP-dependent transcription factor ATF-2 (ATF2)	OTNIZPEA	ATF2_HUMAN	Increases Expression	[10]
Ribosyldihydronicotinamide dehydrogenase (NQO2)	OTGDAJRZ	NQO2_HUMAN	Decreases Expression	[10]
Natriuretic peptides B (NPPB)	OTSN2IPY	ANFB_HUMAN	Decreases Expression	[10]
Early growth response protein 1 (EGR1)	OTCP6XGZ	EGR1_HUMAN	Increases Expression	[10]
Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A)	OT2D9DOV	TNR1A_HUMAN	Increases Expression	[10]
Follistatin (FST)	OTRIVK9Y	FST_HUMAN	Decreases Expression	[10]
Ras-related protein Rab-3B (RAB3B)	OTZA4SXL	RAB3B_HUMAN	Increases Expression	[10]
Lactoperoxidase (LPO)	OTJ9QKX9	PERL_HUMAN	Decreases Expression	[41]
Brain-derived neurotrophic factor (BDNF)	OTLGH7EW	BDNF_HUMAN	Decreases Expression	[10]
Growth arrest and DNA damage-inducible protein GADD45 alpha (GADD45A)	OTDRV63V	GA45A_HUMAN	Increases Expression	[10]
Insulin-like growth factor-binding protein 6 (IGFBP6)	OTW878VI	IBP6_HUMAN	Increases Expression	[35]
Adenomatous polyposis coli protein (APC)	OTKV0TIK	APC_HUMAN	Decreases Expression	[10]
Bromodomain-containing protein 2 (BRD2)	OTQP2MVJ	BRD2_HUMAN	Decreases Expression	[10]
Proteasome subunit alpha type-2 (PSMA2)	OTJRT2ZL	PSA2_HUMAN	Decreases Expression	[10]
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (MGAT1)	OT1E09PZ	MGAT1_HUMAN	Decreases Expression	[10]
G0/G1 switch protein 2 (G0S2)	OT8FL49L	G0S2_HUMAN	Decreases Expression	[10]
DNA repair nuclease/redox regulator APEX1 (APEX1)	OT53OI14	APEX1_HUMAN	Decreases Expression	[10]
Proteasome subunit beta type-4 (PSMB4)	OTOJ9OHA	PSB4_HUMAN	Increases Expression	[10]
Probable global transcription activator SNF2L1 (SMARCA1)	OT0Y6PTU	SMCA1_HUMAN	Decreases Expression	[10]
RNA-binding motif, single-stranded-interacting protein 1 (RBMS1)	OTD13PJN	RBMS1_HUMAN	Decreases Expression	[10]
Myristoylated alanine-rich C-kinase substrate (MARCKS)	OT7N056G	MARCS_HUMAN	Increases Expression	[10]
Large ribosomal subunit protein uL11 (RPL12)	OTIUAQDN	RL12_HUMAN	Increases Expression	[10]
Alpha-2-macroglobulin receptor-associated protein (LRPAP1)	OT6DVD2Q	AMRP_HUMAN	Decreases Expression	[10]
Oxytocin receptor (OXTR)	OT7WFW4U	OXYR_HUMAN	Decreases Expression	[10]
Sorcin (SRI)	OT4R3EAC	SORCN_HUMAN	Decreases Expression	[10]
Homeobox protein Hox-A10 (HOXA10)	OTB6GQ09	HXA10_HUMAN	Increases Expression	[42]
Homeobox protein Hox-A9 (HOXA9)	OTKNK5H0	HXA9_HUMAN	Increases Expression	[43]
Ribonucleoside-diphosphate reductase subunit M2 (RRM2)	OTOB6J6R	RIR2_HUMAN	Increases Expression	[10]
3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH)	OTCMMMIZ	3HIDH_HUMAN	Increases Expression	[10]
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1)	OTFRWOLM	HNRH1_HUMAN	Increases Expression	[10]
Stress-induced-phosphoprotein 1 (STIP1)	OT7TXLOX	STIP1_HUMAN	Decreases Expression	[10]
ETS-related transcription factor Elf-1 (ELF1)	OTV5LKIA	ELF1_HUMAN	Increases Expression	[10]
Syntaxin-2 (STX2)	OTO2IDDR	STX2_HUMAN	Increases Expression	[10]
Catenin beta-1 (CTNNB1)	OTZ932A3	CTNB1_HUMAN	Increases Expression	[10]
Sepiapterin reductase (SPR)	OT1ROA8B	SPRE_HUMAN	Decreases Expression	[10]
Transcription factor SOX-5 (SOX5)	OTEVJHMZ	SOX5_HUMAN	Increases Expression	[10]
Glutaredoxin-1 (GLRX)	OT0QHTAR	GLRX1_HUMAN	Decreases Expression	[10]
Aryl hydrocarbon receptor (AHR)	OTFE4EYE	AHR_HUMAN	Affects Binding	[44]
Transaldolase (TALDO1)	OTDKV2S2	TALDO_HUMAN	Increases Expression	[10]
Adenylyl cyclase-associated protein 2 (CAP2)	OTC1WFNO	CAP2_HUMAN	Decreases Expression	[10]
Trifunctional enzyme subunit alpha, mitochondrial (HADHA)	OTO557N2	ECHA_HUMAN	Decreases Expression	[10]
N-alpha-acetyltransferase 10 (NAA10)	OTYB9R6I	NAA10_HUMAN	Decreases Expression	[10]
Serine/threonine-protein kinase mTOR (MTOR)	OTHH8KU7	MTOR_HUMAN	Decreases Expression	[41]
Caspase-3 (CASP3)	OTIJRBE7	CASP3_HUMAN	Increases Activity	[45]
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A)	OTDPS6AV	STT3A_HUMAN	Increases Expression	[10]
Guanine nucleotide exchange factor MSS4 (RABIF)	OTEW72FR	MSS4_HUMAN	Decreases Expression	[10]
DNA-binding protein inhibitor ID-4 (ID4)	OTPMJ39I	ID4_HUMAN	Increases Expression	[10]
Glioma pathogenesis-related protein 1 (GLIPR1)	OT0FGQK7	GLIP1_HUMAN	Increases Expression	[10]
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (PIP4K2A)	OTO9JO9U	PI42A_HUMAN	Increases Expression	[10]
CCN family member 3 (CCN3)	OTOW5YL4	CCN3_HUMAN	Decreases Expression	[10]
Nuclear autoantigenic sperm protein (NASP)	OTNE4THC	NASP_HUMAN	Increases Expression	[10]
GMP synthase (GMPS)	OTDC90IS	GUAA_HUMAN	Decreases Expression	[10]
Rab GDP dissociation inhibitor beta (GDI2)	OTGLY3I7	GDIB_HUMAN	Increases Expression	[10]
Palmitoyl-protein thioesterase 1 (PPT1)	OTM3S4DE	PPT1_HUMAN	Decreases Expression	[10]
Ras-related protein Rab-9A (RAB9A)	OTO9VJS9	RAB9A_HUMAN	Increases Expression	[10]
Thiopurine S-methyltransferase (TPMT)	OTFOX70W	TPMT_HUMAN	Decreases Expression	[10]
Nuclear cap-binding protein subunit 2 (NCBP2)	OTQNZTE4	NCBP2_HUMAN	Decreases Expression	[10]
Rap1 GTPase-GDP dissociation stimulator 1 (RAP1GDS1)	OTH70UHD	GDS1_HUMAN	Increases Expression	[10]
Rho GDP-dissociation inhibitor 1 (ARHGDIA)	OTEXWJDO	GDIR1_HUMAN	Decreases Expression	[12]
Spermine synthase (SMS)	OT8JYKNH	SPSY_HUMAN	Decreases Expression	[10]
Stanniocalcin-1 (STC1)	OTGVVXYF	STC1_HUMAN	Increases Expression	[10]
Biliverdin reductase A (BLVRA)	OTTSEKLZ	BIEA_HUMAN	Decreases Expression	[10]
Arfaptin-2 (ARFIP2)	OTK9JXIJ	ARFP2_HUMAN	Decreases Expression	[10]
Coatomer subunit alpha (COPA)	OTZ1DTXU	COPA_HUMAN	Decreases Expression	[10]
Phospholipase A and acyltransferase 3 (PLAAT3)	OTVXXJ5K	PLAT3_HUMAN	Increases Expression	[10]
Solute carrier family 12 member 2 (SLC12A2)	OT3ZJ3LH	S12A2_HUMAN	Decreases Expression	[12]
Protein AF-10 (MLLT10)	OTURMDV7	AF10_HUMAN	Increases Expression	[10]
ATP synthase subunit f, mitochondrial (ATP5MF)	OTE4TBG9	ATPK_HUMAN	Decreases Expression	[10]
Sestrin-3 (SESN3)	OTJRY1Y5	SESN3_HUMAN	Decreases Expression	[10]
Actin, cytoplasmic 1 (ACTB)	OT1MCP2F	ACTB_HUMAN	Increases Expression	[10]
Large ribosomal subunit protein eL15 (RPL15)	OT7Y42LL	RL15_HUMAN	Decreases Expression	[10]
Transforming protein RhoA (RHOA)	OT6YOJ9N	RHOA_HUMAN	Decreases Expression	[10]
Protein transport protein Sec61 subunit alpha isoform 1 (SEC61A1)	OTLBE3CB	S61A1_HUMAN	Decreases Expression	[10]
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (DAD1)	OTUUNQBT	DAD1_HUMAN	Decreases Expression	[10]
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PPP1CB)	OTYFTYFR	PP1B_HUMAN	Increases Expression	[10]
ADP-ribosylation factor 6 (ARF6)	OTVV7KJO	ARF6_HUMAN	Increases Expression	[10]
Estrogen-related receptor gamma (ESRRG)	OTC3A0KU	ERR3_HUMAN	Affects Binding	[46]
Actin, aortic smooth muscle (ACTA2)	OTEDLG8E	ACTA_HUMAN	Decreases Expression	[10]
Ras-related protein Rap-1A (RAP1A)	OT5RH6TI	RAP1A_HUMAN	Decreases Expression	[10]
Small ribosomal subunit protein eS25 (RPS25)	OTKLWED2	RS25_HUMAN	Increases Expression	[10]
DNA-directed RNA polymerases I, II, and III subunit RPABC5 (POLR2L)	OTSSOMUP	RPAB5_HUMAN	Decreases Expression	[10]
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PPP2R2A)	OT9297OG	2ABA_HUMAN	Increases Expression	[10]
Small ribosomal subunit protein RACK1 (RACK1)	OTZBCQ1U	RACK1_HUMAN	Increases Expression	[47]
Actin, gamma-enteric smooth muscle (ACTG2)	OTRDWUO0	ACTH_HUMAN	Increases Expression	[10]
Phosphoserine phosphatase (PSPH)	OTV1PVAX	SERB_HUMAN	Increases Expression	[10]
Eukaryotic translation initiation factor 4 gamma 2 (EIF4G2)	OTEO98CR	IF4G2_HUMAN	Decreases Expression	[10]
Butyrophilin subfamily 3 member A2 (BTN3A2)	OT3DIBU3	BT3A2_HUMAN	Increases Expression	[10]
Protein jagged-1 (JAG1)	OT3LGT6K	JAG1_HUMAN	Increases Expression	[48]
Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC1S1)	OT123376	BL1S1_HUMAN	Decreases Expression	[10]
High mobility group nucleosome-binding domain-containing protein 5 (HMGN5)	OTUUAHVQ	HMGN5_HUMAN	Increases Expression	[10]
ADP-ribosylation factor 5 (ARF5)	OTZO9S3U	ARF5_HUMAN	Decreases Expression	[10]
Cytochrome c (CYCS)	OTBFALJD	CYC_HUMAN	Affects Localization	[45]
Heat shock factor protein 1 (HSF1)	OTYNJ4KP	HSF1_HUMAN	Increases Activity	[49]
Protein SET (SET)	OTGYYQJO	SET_HUMAN	Increases Expression	[10]
Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMGCS1)	OTCO26FV	HMCS1_HUMAN	Decreases Expression	[10]
Protein Dr1 (DR1)	OTR081M4	NC2B_HUMAN	Decreases Expression	[10]
cAMP-responsive element modulator (CREM)	OTJIJ5AL	CREM_HUMAN	Increases Expression	[10]
Caveolin-1 (CAV1)	OTEZUR1L	CAV1_HUMAN	Increases Expression	[10]
Antigen peptide transporter 2 (TAP2)	OTWSYFI7	TAP2_HUMAN	Increases Expression	[10]
Transcription factor p65 (RELA)	OTUJP9CN	TF65_HUMAN	Increases Activity	[50]
Sialomucin core protein 24 (CD164)	OTZ7FIU8	MUC24_HUMAN	Decreases Expression	[10]
Tyrosine-protein phosphatase non-receptor type 12 (PTPN12)	OT5WA666	PTN12_HUMAN	Decreases Expression	[10]
Serine/arginine-rich splicing factor 11 (SRSF11)	OTZSV6CZ	SRS11_HUMAN	Decreases Expression	[10]
Early growth response protein 3 (EGR3)	OTGPJIRA	EGR3_HUMAN	Increases Expression	[12]
KH domain-containing, RNA-binding, signal transduction-associated protein 1 (KHDRBS1)	OT5GO2PL	KHDR1_HUMAN	Increases Expression	[10]
Rho GTPase-activating protein 1 (ARHGAP1)	OT0H2ZBZ	RHG01_HUMAN	Increases Expression	[10]
ATP-dependent RNA helicase A (DHX9)	OT5AAOQI	DHX9_HUMAN	Increases Expression	[10]
Calmodulin-regulated spectrin-associated protein 2 (CAMSAP2)	OT9KXWE7	CAMP2_HUMAN	Decreases Expression	[10]
Tripartite motif-containing protein 26 (TRIM26)	OTS0DJIP	TRI26_HUMAN	Increases Expression	[10]
Protein Red (IK)	OTWSSXX0	RED_HUMAN	Decreases Expression	[10]
Heterogeneous nuclear ribonucleoprotein A0 (HNRNPA0)	OTCP792K	ROA0_HUMAN	Increases Expression	[10]
Methanethiol oxidase (SELENBP1)	OT3NZNTR	SBP1_HUMAN	Decreases Expression	[12]
S-phase kinase-associated protein 2 (SKP2)	OTD5B41X	SKP2_HUMAN	Decreases Expression	[10]
Acid ceramidase (ASAH1)	OT1DNGXL	ASAH1_HUMAN	Increases Expression	[10]
Serine/threonine-protein kinase PRP4 homolog (PRP4K)	OT4C7XNK	PRP4B_HUMAN	Decreases Expression	[10]
Eukaryotic translation initiation factor 4E-binding protein 2 (EIF4EBP2)	OT3M8WEU	4EBP2_HUMAN	Increases Expression	[10]
Transformer-2 protein homolog alpha (TRA2A)	OT5NHOO3	TRA2A_HUMAN	Increases Expression	[10]
Periodic tryptophan protein 1 homolog (PWP1)	OTUKXP1E	PWP1_HUMAN	Decreases Expression	[10]
Cullin-2 (CUL2)	OTPF83PG	CUL2_HUMAN	Increases Expression	[10]
Cullin-3 (CUL3)	OTDNOAPM	CUL3_HUMAN	Decreases Expression	[10]
GDP-L-fucose synthase (GFUS)	OT4EDVGT	FCL_HUMAN	Increases Expression	[10]
Angio-associated migratory cell protein (AAMP)	OTZXBSS4	AAMP_HUMAN	Increases Expression	[10]
Transcription factor Dp-2 (TFDP2)	OTKQFX5H	TFDP2_HUMAN	Decreases Expression	[10]
Four and a half LIM domains protein 2 (FHL2)	OT0OAYWT	FHL2_HUMAN	Decreases Expression	[10]
Translation initiation factor eIF2B subunit alpha (EIF2B1)	OT4NCVY1	EI2BA_HUMAN	Decreases Expression	[10]
Eukaryotic initiation factor 4A-II (EIF4A2)	OT08H03R	IF4A2_HUMAN	Decreases Expression	[10]
Caprin-1 (CAPRIN1)	OTEJAMS3	CAPR1_HUMAN	Decreases Expression	[10]
Squalene monooxygenase (SQLE)	OT0GGRDO	ERG1_HUMAN	Decreases Expression	[10]
Golgin subfamily B member 1 (GOLGB1)	OT2S0GK8	GOGB1_HUMAN	Decreases Expression	[10]
Nuclear receptor subfamily 1 group I member 3 (NR1I3)	OTS3SGH7	NR1I3_HUMAN	Increases Activity	[51]
Proteasome activator complex subunit 4 (PSME4)	OTDGF53O	PSME4_HUMAN	Decreases Expression	[10]
GTPase-activating protein and VPS9 domain-containing protein 1 (GAPVD1)	OT5K42IK	GAPD1_HUMAN	Increases Expression	[10]
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 (ACAP2)	OTYNZPC4	ACAP2_HUMAN	Increases Expression	[10]
Inorganic pyrophosphatase (PPA1)	OTHZK1QB	IPYR_HUMAN	Decreases Expression	[10]
Receptor-type tyrosine-protein phosphatase kappa (PTPRK)	OTAP5AT3	PTPRK_HUMAN	Decreases Expression	[10]
Pumilio homolog 3 (PUM3)	OTN1IPNS	PUM3_HUMAN	Increases Expression	[10]
Calponin-3 (CNN3)	OTJTAXAP	CNN3_HUMAN	Increases Expression	[10]
Protein phosphatase 1 regulatory subunit 7 (PPP1R7)	OTY5IE69	PP1R7_HUMAN	Decreases Expression	[10]
Thyroid receptor-interacting protein 6 (TRIP6)	OTIPA4ZR	TRIP6_HUMAN	Decreases Expression	[10]
Tubulin-specific chaperone C (TBCC)	OTBF0X8R	TBCC_HUMAN	Decreases Expression	[10]
Coiled-coil domain-containing protein 85B (CCDC85B)	OTKEQLNK	CC85B_HUMAN	Decreases Expression	[10]
Histone-lysine N-methyltransferase EZH2 (EZH2)	OTIEHTKW	EZH2_HUMAN	Increases Expression	[52]
DNA damage-binding protein 1 (DDB1)	OTTR2L3Z	DDB1_HUMAN	Increases Expression	[10]
Mitogen-activated protein kinase 14 (MAPK14)	OT5TCO3O	MK14_HUMAN	Decreases Expression	[10]
Large ribosomal subunit protein uL23m (MRPL23)	OT7H7PM2	RM23_HUMAN	Decreases Expression	[10]
Calcium/calmodulin-dependent protein kinase type IV (CAMK4)	OT47RDGV	KCC4_HUMAN	Increases Activity	[50]
Serine/arginine-rich splicing factor 7 (SRSF7)	OTRS4W4S	SRSF7_HUMAN	Decreases Expression	[10]
Drebrin (DBN1)	OTZVKG8A	DREB_HUMAN	Increases Expression	[10]
V-type proton ATPase subunit F (ATP6V1F)	OTSTT8JG	VATF_HUMAN	Decreases Expression	[10]
DNA repair protein SWI5 homolog (SWI5)	OT6CH5UO	SWI5_HUMAN	Increases Expression	[10]
WD40 repeat-containing protein SMU1 (SMU1)	OTLCSLGL	SMU1_HUMAN	Increases Expression	[10]
N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (GNPTAB)	OT2Z03OB	GNPTA_HUMAN	Decreases Expression	[10]
Protein FAM229B (FAM229B)	OT14WA0Z	F229B_HUMAN	Decreases Expression	[10]
Prolyl endopeptidase-like (PREPL)	OTN5XMLZ	PPCEL_HUMAN	Increases Expression	[10]
Programmed cell death protein 4 (PDCD4)	OTZ6NXUX	PDCD4_HUMAN	Increases Expression	[10]
Protein Hikeshi (HIKESHI)	OTPKV3UZ	HIKES_HUMAN	Increases Expression	[10]
Shugoshin 2 (SGO2)	OTNGJDS8	SGO2_HUMAN	Increases Expression	[10]
Protein FAM133B (FAM133B)	OTQH2A95	F133B_HUMAN	Decreases Expression	[10]
SH3 domain-containing protein 19 (SH3D19)	OTVU3VS2	SH319_HUMAN	Increases Expression	[10]
Polynucleotide 5'-hydroxyl-kinase NOL9 (NOL9)	OTCCIJ8I	NOL9_HUMAN	Increases Expression	[10]
Tumor protein p63-regulated gene 1-like protein (TPRG1L)	OTU7GPKK	TPRGL_HUMAN	Decreases Expression	[10]
Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (PDZK1)	OTGFK4MH	NHRF3_HUMAN	Increases Expression	[40]
Early estrogen-induced gene 1 protein (EEIG1)	OT2BMEAE	EEIG1_HUMAN	Increases Expression	[40]
DEP domain-containing protein 1A (DEPDC1)	OT0JWE1B	DEP1A_HUMAN	Increases Expression	[10]
Serine/threonine-protein kinase MRCK alpha (CDC42BPA)	OTCPFOSA	MRCKA_HUMAN	Decreases Expression	[10]
Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1)	OTA0SGNE	CDKAL_HUMAN	Increases Expression	[10]
SPRY domain-containing protein 7 (SPRYD7)	OT6FTW9Z	SPRY7_HUMAN	Decreases Expression	[10]
Metalloreductase STEAP3 (STEAP3)	OTS9GZK5	STEA3_HUMAN	Decreases Expression	[10]
Secreted frizzled-related protein 4 (SFRP4)	OT8PQUVB	SFRP4_HUMAN	Decreases Expression	[10]
OTU domain-containing protein 7B (OTUD7B)	OTMVM8R7	OTU7B_HUMAN	Increases Expression	[10]
Eukaryotic translation initiation factor 5A-1-like (EIF5AL1)	OTLA4ONW	IF5AL_HUMAN	Increases Expression	[10]
Rhomboid domain-containing protein 2 (RHBDD2)	OTX54ILM	RHBD2_HUMAN	Decreases Expression	[10]
tRNA N(3)-methylcytidine methyltransferase METTL2B (METTL2B)	OT0NT3WJ	MET2B_HUMAN	Increases Expression	[10]
Superkiller complex protein 3 (SKIC3)	OTTB3AVE	SKI3_HUMAN	Increases Expression	[10]
Spindle assembly abnormal protein 6 homolog (SASS6)	OT1V8H40	SAS6_HUMAN	Increases Expression	[53]
Cytochrome P450 20A1 (CYP20A1)	OTIUZ6CF	CP20A_HUMAN	Decreases Expression	[10]
Beta-1,3-glucosyltransferase (B3GLCT)	OTXH6KOQ	B3GLT_HUMAN	Decreases Expression	[10]
Lysophospholipid acyltransferase 2 (MBOAT2)	OTZI3BXD	MBOA2_HUMAN	Increases Expression	[10]
Protein O-mannosyl-transferase TMTC3 (TMTC3)	OTMTTDYG	TMTC3_HUMAN	Increases Expression	[10]
Centromere protein U (CENPU)	OTQ4TZRS	CENPU_HUMAN	Decreases Expression	[10]
Nucleolar protein 8 (NOL8)	OT6RZLH3	NOL8_HUMAN	Decreases Expression	[10]
Protein RUFY3 (RUFY3)	OTMA4YA4	RUFY3_HUMAN	Increases Expression	[10]
BTB/POZ domain-containing protein KCTD9 (KCTD9)	OTBN6ZUC	KCTD9_HUMAN	Decreases Expression	[10]
Eukaryotic translation initiation factor 3 subunit M (EIF3M)	OTVWEV60	EIF3M_HUMAN	Increases Expression	[10]
G2/M phase-specific E3 ubiquitin-protein ligase (G2E3)	OT06BFRQ	G2E3_HUMAN	Decreases Expression	[10]
Rab11 family-interacting protein 2 (RAB11FIP2)	OTTX9RWE	RFIP2_HUMAN	Increases Expression	[10]
Protein lifeguard 1 (GRINA)	OTMC1O66	LFG1_HUMAN	Increases Expression	[10]
Neuroepithelial cell-transforming gene 1 protein (NET1)	OTZHNMJV	ARHG8_HUMAN	Increases Expression	[10]
Large ribosomal subunit protein mL55 (MRPL55)	OTA9KF6B	RM55_HUMAN	Decreases Expression	[10]
Transmembrane emp24 domain-containing protein 4 (TMED4)	OTLVPY2E	TMED4_HUMAN	Increases Expression	[10]
Polypeptide N-acetylgalactosaminyltransferase 10 (GALNT10)	OTZ6FDOL	GLT10_HUMAN	Increases Expression	[10]
Probable RNA-binding protein 23 (RBM23)	OTDNGLHY	RBM23_HUMAN	Decreases Expression	[10]
Serine incorporator 5 (SERINC5)	OT3COPVF	SERC5_HUMAN	Increases Expression	[10]
Cullin-associated NEDD8-dissociated protein 1 (CAND1)	OTGB6NU0	CAND1_HUMAN	Decreases Expression	[10]
Transmembrane protein adipocyte-associated 1 (TPRA1)	OTL61503	TPRA1_HUMAN	Decreases Expression	[10]
Mitofusin-1 (MFN1)	OTCBXQZF	MFN1_HUMAN	Increases Expression	[10]
PHD finger protein 6 (PHF6)	OT8DXI40	PHF6_HUMAN	Increases Expression	[10]
Cytoskeleton-associated protein 2-like (CKAP2L)	OT4T73GG	CKP2L_HUMAN	Decreases Expression	[10]
Chondroitin sulfate synthase 2 (CHPF)	OTLMP2VY	CHSS2_HUMAN	Decreases Expression	[10]
GTP-binding protein 8 (GTPBP8)	OTI8X03A	GTPB8_HUMAN	Decreases Expression	[10]
Small integral membrane protein 20 (SMIM20)	OTZI1KFR	SIM20_HUMAN	Decreases Expression	[10]
ARL14 effector protein (ARL14EP)	OTVMRFIN	AL14E_HUMAN	Increases Expression	[10]
Probable RNA-binding protein EIF1AD (EIF1AD)	OT3EXB6S	EIF1A_HUMAN	Increases Expression	[10]
Zinc finger protein GLIS3 (GLIS3)	OTBC960E	GLIS3_HUMAN	Decreases Expression	[10]
Zinc transporter 7 (SLC30A7)	OTC55IN4	ZNT7_HUMAN	Increases Expression	[10]
Periphilin-1 (PPHLN1)	OTWG1WIH	PPHLN_HUMAN	Decreases Expression	[10]
FAD synthase (FLAD1)	OTY8R02L	FAD1_HUMAN	Decreases Expression	[10]
Retinoic acid-induced protein 3 (GPRC5A)	OTPOCWR7	RAI3_HUMAN	Increases Expression	[10]
Lysine-specific demethylase 2B (KDM2B)	OTDMCVW7	KDM2B_HUMAN	Increases Expression	[10]
Multiple coagulation factor deficiency protein 2 (MCFD2)	OTM0XU0U	MCFD2_HUMAN	Decreases Expression	[10]
Phosphatidylinositol-glycan biosynthesis class X protein (PIGX)	OTUN0WC4	PIGX_HUMAN	Decreases Expression	[10]
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (PIP4K2C)	OTHRWR93	PI42C_HUMAN	Increases Expression	[10]
E3 ubiquitin-protein ligase DTX3L (DTX3L)	OTCCO2QZ	DTX3L_HUMAN	Decreases Expression	[10]
Histone deacetylase 7 (HDAC7)	OTQ3P0XA	HDAC7_HUMAN	Decreases Expression	[28]
Pleckstrin homology-like domain family A member 1 (PHLDA1)	OTFTWMIQ	PHLA1_HUMAN	Increases Expression	[10]
RING finger protein 141 (RNF141)	OT07ANSG	RN141_HUMAN	Decreases Expression	[10]
Sec1 family domain-containing protein 1 (SCFD1)	OTN4T7JI	SCFD1_HUMAN	Decreases Expression	[10]
tRNA-splicing endonuclease subunit Sen15 (TSEN15)	OT14UW31	SEN15_HUMAN	Increases Expression	[10]
Stalled ribosome sensor GCN1 (GCN1)	OTBFVD7Z	GCN1_HUMAN	Decreases Expression	[10]
Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B)	OT3SQMLU	AN32B_HUMAN	Increases Expression	[10]
Estrogen receptor beta (ESR2)	OTXNR2WQ	ESR2_HUMAN	Increases Activity	[54]
Ras-responsive element-binding protein 1 (RREB1)	OT62460U	RREB1_HUMAN	Increases Expression	[10]
Gamma-glutamyl hydrolase (GGH)	OTL71J7T	GGH_HUMAN	Increases Expression	[10]
BLOC-3 complex member HPS1 (HPS1)	OTKS5I7T	HPS1_HUMAN	Decreases Expression	[10]
GTP-binding protein Rit1 (RIT1)	OTVNOGOH	RIT1_HUMAN	Increases Expression	[10]
Ninjurin-1 (NINJ1)	OTLRZ1EU	NINJ1_HUMAN	Increases Expression	[10]
Pre-rRNA-processing protein TSR2 homolog (TSR2)	OTSIWJQJ	TSR2_HUMAN	Decreases Expression	[10]
Transmembrane protein 54 (TMEM54)	OTPQEFR0	TMM54_HUMAN	Increases Expression	[10]
Endonuclease 8-like 2 (NEIL2)	OTV6JEON	NEIL2_HUMAN	Increases Expression	[10]
Polyamine deacetylase HDAC10 (HDAC10)	OTHCKKUQ	HDA10_HUMAN	Decreases Expression	[28]
E3 ubiquitin-protein ligase RNF25 (RNF25)	OTQJSBEG	RNF25_HUMAN	Increases Expression	[10]
Mitochondrial assembly of ribosomal large subunit protein 1 (MALSU1)	OT7LQ36N	MASU1_HUMAN	Affects Expression	[10]
C1GALT1-specific chaperone 1 (C1GALT1C1)	OTRTZUF5	C1GLC_HUMAN	Decreases Expression	[10]
Corrinoid adenosyltransferase MMAB (MMAB)	OTOWOEJN	MMAB_HUMAN	Increases Expression	[10]
PDZ and LIM domain protein 5 (PDLIM5)	OTLQVV22	PDLI5_HUMAN	Increases Expression	[10]
Small integral membrane protein 10 (SMIM10)	OTISM8ZT	SIM10_HUMAN	Decreases Expression	[10]
DnaJ homolog subfamily C member 1 (DNAJC1)	OTCKFOZ0	DNJC1_HUMAN	Decreases Expression	[10]
Histone-lysine N-methyltransferase, H3 lysine-36 specific (NSD1)	OTLV02OJ	NSD1_HUMAN	Decreases Expression	[10]
Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 (PCMTD1)	OT5TS6P7	PCMD1_HUMAN	Decreases Expression	[10]
Dedicator of cytokinesis protein 7 (DOCK7)	OTINNVQV	DOCK7_HUMAN	Decreases Expression	[10]
Erbin (ERBIN)	OTNWTUA8	ERBIN_HUMAN	Affects Expression	[10]
Selenocysteine insertion sequence-binding protein 2 (SECISBP2)	OTBXUURJ	SEBP2_HUMAN	Decreases Expression	[10]
26S proteasome non-ATPase regulatory subunit 1 (PSMD1)	OTW258OV	PSMD1_HUMAN	Decreases Expression	[10]
E3 ubiquitin-protein ligase RING2 (RNF2)	OTFPLOIN	RING2_HUMAN	Increases Expression	[10]
G-protein coupled estrogen receptor 1 (GPER1)	OTUK0TDC	GPER1_HUMAN	Increases Expression	[55]
Cell division cycle-associated protein 3 (CDCA3)	OTUI8QK3	CDCA3_HUMAN	Decreases Expression	[10]
COP9 signalosome complex subunit 8 (COPS8)	OTNAD2S4	CSN8_HUMAN	Decreases Expression	[10]
Lysosomal-trafficking regulator (LYST)	OTIUB1B3	LYST_HUMAN	Decreases Expression	[10]
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1A)	OTVTB5R5	PI51A_HUMAN	Increases Expression	[10]
Homeobox protein Nkx-3.1 (NKX3-1)	OT0DO6ZU	NKX31_HUMAN	Increases Expression	[10]
T-complex protein 1 subunit eta (CCT7)	OTQNM3CY	TCPH_HUMAN	Decreases Expression	[10]
Plakophilin-2 (PKP2)	OTJOVF68	PKP2_HUMAN	Increases Expression	[10]
Actin-related protein 2/3 complex subunit 5-like protein (ARPC5L)	OTBNRHOZ	ARP5L_HUMAN	Decreases Expression	[10]
Target of rapamycin complex 2 subunit MAPKAP1 (MAPKAP1)	OTYKB9G3	SIN1_HUMAN	Increases Expression	[10]
Protein CMSS1 (CMSS1)	OTHASLWD	CMS1_HUMAN	Decreases Expression	[10]
Vesicle-trafficking protein SEC22c (SEC22C)	OTMG6NG0	SC22C_HUMAN	Increases Expression	[10]
Nucleolar protein 10 (NOL10)	OTC4R5O7	NOL10_HUMAN	Increases Expression	[10]
Deubiquitinase DESI2 (DESI2)	OTHUOKOC	DESI2_HUMAN	Decreases Expression	[10]
NEDD4 family-interacting protein 1 (NDFIP1)	OTIORSWF	NFIP1_HUMAN	Decreases Expression	[10]
Plasma alpha-L-fucosidase (FUCA2)	OTY5NVMJ	FUCO2_HUMAN	Increases Expression	[10]
Acireductone dioxygenase (ADI1)	OT8IOD03	MTND_HUMAN	Decreases Expression	[10]
Guanine nucleotide-binding protein-like 3 (GNL3)	OTILGYO4	GNL3_HUMAN	Decreases Expression	[10]
TM2 domain-containing protein 1 (TM2D1)	OTWA4YSR	TM2D1_HUMAN	Decreases Expression	[10]
Ion channel TACAN (TMEM120A)	OTBS3YWY	TACAN_HUMAN	Decreases Expression	[10]
GTP-binding protein 4 (GTPBP4)	OT6ZHAWC	GTPB4_HUMAN	Decreases Expression	[10]
Protein Niban 1 (NIBAN1)	OTYOLI12	NIBA1_HUMAN	Decreases Expression	[10]
Tripartite motif-containing protein 5 (TRIM5)	OTMZH7EJ	TRIM5_HUMAN	Increases Expression	[10]
Phospholysine phosphohistidine inorganic pyrophosphate phosphatase (LHPP)	OT9AGAIJ	LHPP_HUMAN	Decreases Expression	[10]
Transmembrane protein 222 (TMEM222)	OTWFLPK2	TM222_HUMAN	Decreases Expression	[10]
Large ribosomal subunit protein uL18m (MRPL18)	OTORKKYC	RM18_HUMAN	Increases Expression	[10]
Inhibitor of growth protein 2 (ING2)	OT6H0EWF	ING2_HUMAN	Decreases Expression	[10]
Cysteine-rich and transmembrane domain-containing protein 1 (CYSTM1)	OT1GYXDM	CYTM1_HUMAN	Decreases Expression	[10]
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 (NUCKS1)	OTL4VJC5	NUCKS_HUMAN	Increases Expression	[10]
Inorganic pyrophosphatase 2, mitochondrial (PPA2)	OTRKV8WW	IPYR2_HUMAN	Decreases Expression	[10]
Mitochondrial translation release factor in rescue (MTRFR)	OTG2GU7J	MTRFR_HUMAN	Decreases Expression	[10]
Aminopeptidase B (RNPEP)	OT1DIWA0	AMPB_HUMAN	Decreases Expression	[10]
TATA box-binding protein-associated factor RNA polymerase I subunit D (TAF1D)	OTOXUDV1	TAF1D_HUMAN	Increases Expression	[10]
Transmembrane protein 134 (TMEM134)	OTBX9H9D	TM134_HUMAN	Increases Expression	[10]
Prostaglandin E synthase 2 (PTGES2)	OTMS4J0P	PGES2_HUMAN	Decreases Expression	[10]
Coenzyme Q-binding protein COQ10 homolog B, mitochondrial (COQ10B)	OTNITN8H	CQ10B_HUMAN	Increases Expression	[10]
Queuine tRNA-ribosyltransferase accessory subunit 2 (QTRT2)	OTLPFRAC	QTRT2_HUMAN	Increases Expression	[10]
Sideroflexin-1 (SFXN1)	OTL66767	SFXN1_HUMAN	Increases Expression	[10]
Ribosome production factor 1 (RPF1)	OT4J1CRC	RPF1_HUMAN	Increases Expression	[10]
Probable cysteine--tRNA ligase, mitochondrial (CARS2)	OTGLZOFP	SYCM_HUMAN	Decreases Expression	[10]
Melanoma-associated antigen F1 (MAGEF1)	OTUU40U3	MAGF1_HUMAN	Decreases Expression	[10]
MYG1 exonuclease (MYG1)	OTIZFDXP	MYG1_HUMAN	Decreases Expression	[10]
Calcyclin-binding protein (CACYBP)	OTJMZD2T	CYBP_HUMAN	Decreases Expression	[10]
Kinetochore protein Spc25 (SPC25)	OTCAS0OH	SPC25_HUMAN	Decreases Expression	[10]
E3 SUMO-protein ligase KIAA1586 (KIAA1586)	OTNPAEB8	K1586_HUMAN	Decreases Expression	[10]
Golgi-associated PDZ and coiled-coil motif-containing protein (GOPC)	OTRBGH71	GOPC_HUMAN	Decreases Expression	[10]
Transcription factor 7-like 2 (TCF7L2)	OTVWPZ8B	TF7L2_HUMAN	Decreases Expression	[10]
N-lysine methyltransferase KMT5A (KMT5A)	OTW2A5YY	KMT5A_HUMAN	Increases Expression	[10]
Translation initiation factor eIF2B subunit gamma (EIF2B3)	OTG6HE7D	EI2BG_HUMAN	Increases Expression	[10]
Cytochrome P450 26B1 (CYP26B1)	OT92XA92	CP26B_HUMAN	Increases Expression	[28]
Bromodomain adjacent to zinc finger domain protein 1A (BAZ1A)	OTWHOVZS	BAZ1A_HUMAN	Decreases Expression	[10]
Lymphoid-specific helicase (HELLS)	OTVVV668	HELLS_HUMAN	Decreases Expression	[10]
Transmembrane 7 superfamily member 3 (TM7SF3)	OTT9RKL6	TM7S3_HUMAN	Decreases Expression	[10]
Phenylalanine--tRNA ligase beta subunit (FARSB)	OT8N9TT5	SYFB_HUMAN	Decreases Expression	[10]
Biogenesis of lysosome-related organelles complex 1 subunit 4 (BLOC1S4)	OTDCFUJC	BL1S4_HUMAN	Decreases Expression	[10]
Cell cycle control protein 50A (TMEM30A)	OTR6N5J2	CC50A_HUMAN	Decreases Expression	[10]
ATPase family AAA domain-containing protein 3A (ATAD3A)	OTWF6HBP	ATD3A_HUMAN	Decreases Expression	[10]
ADP-ribosylation factor-like protein 8B (ARL8B)	OTD5TJIN	ARL8B_HUMAN	Decreases Expression	[10]
Armadillo repeat-containing protein 1 (ARMC1)	OT1IZW7W	ARMC1_HUMAN	Decreases Expression	[10]
Protein SDA1 homolog (SDAD1)	OTP4468N	SDA1_HUMAN	Increases Expression	[10]
Arginine and glutamate-rich protein 1 (ARGLU1)	OTRVRZ4Z	ARGL1_HUMAN	Increases Expression	[10]
CXXC motif containing zinc binding protein (CZIB)	OTMEJ7M1	CZIB_HUMAN	Decreases Expression	[10]
COMM domain-containing protein 8 (COMMD8)	OTRMN4EU	COMD8_HUMAN	Increases Expression	[10]
PH and SEC7 domain-containing protein 3 (PSD3)	OTTN9B9O	PSD3_HUMAN	Decreases Expression	[10]
CDGSH iron-sulfur domain-containing protein 1 (CISD1)	OT0MTVGF	CISD1_HUMAN	Decreases Expression	[10]
Methionine adenosyltransferase 2 subunit beta (MAT2B)	OT4Y7T9L	MAT2B_HUMAN	Increases Expression	[10]
Cysteine-rich motor neuron 1 protein (CRIM1)	OTTZNV6Y	CRIM1_HUMAN	Increases Expression	[10]
Protein PALS2 (PALS2)	OTV12NKE	PALS2_HUMAN	Increases Expression	[10]
COMM domain-containing protein 9 (COMMD9)	OT3IZ61B	COMD9_HUMAN	Decreases Expression	[10]
Cysteine-rich PDZ-binding protein (CRIPT)	OTA6M8M4	CRIPT_HUMAN	Increases Expression	[10]
Serine/threonine-protein kinase pim-2 (PIM2)	OTHQGU3I	PIM2_HUMAN	Increases Expression	[10]
Dolichol-phosphate mannosyltransferase subunit 3 (DPM3)	OTSB4XO0	DPM3_HUMAN	Decreases Expression	[10]
Carboxypeptidase A4 (CPA4)	OT66MP0F	CBPA4_HUMAN	Increases Expression	[10]
GTP:AMP phosphotransferase AK3, mitochondrial (AK3)	OTM59ZGG	KAD3_HUMAN	Decreases Expression	[10]
SH3 domain-binding glutamic acid-rich-like protein 2 (SH3BGRL2)	OTOX4XT7	SH3L2_HUMAN	Increases Expression	[10]
Motile sperm domain-containing protein 1 (MOSPD1)	OT993HTH	MSPD1_HUMAN	Decreases Expression	[10]
Inhibitor of growth protein 1 (ING1)	OTEZBRKW	ING1_HUMAN	Decreases Expression	[10]
Polypyrimidine tract-binding protein 2 (PTBP2)	OTF4S7NE	PTBP2_HUMAN	Increases Expression	[10]
TRAF2 and NCK-interacting protein kinase (TNIK)	OTDZBJ4K	TNIK_HUMAN	Decreases Expression	[10]
DCC-interacting protein 13-alpha (APPL1)	OT8VR95S	DP13A_HUMAN	Decreases Expression	[10]
CASP8-associated protein 2 (CASP8AP2)	OTTWT68S	C8AP2_HUMAN	Affects Expression	[10]
Apoptotic chromatin condensation inducer in the nucleus (ACIN1)	OTK81F92	ACINU_HUMAN	Decreases Expression	[10]
Protein argonaute-2 (AGO2)	OT4JY32Q	AGO2_HUMAN	Decreases Expression	[10]
Neudesin (NENF)	OTGL7MHB	NENF_HUMAN	Decreases Expression	[10]
Proliferation-associated protein 2G4 (PA2G4)	OT7IG7HT	PA2G4_HUMAN	Decreases Expression	[10]
C-C motif chemokine 26 (CCL26)	OT2B7HR9	CCL26_HUMAN	Affects Expression	[10]
Exocyst complex component 6B (EXOC6B)	OTFI1IPG	EXC6B_HUMAN	Increases Expression	[10]
Kelch-like protein 20 (KLHL20)	OTC0SFS9	KLH20_HUMAN	Decreases Expression	[10]
Axin-2 (AXIN2)	OTRMGQNU	AXIN2_HUMAN	Decreases Expression	[28]
AP-3 complex subunit mu-1 (AP3M1)	OTOQYRSL	AP3M1_HUMAN	Decreases Expression	[10]
Nucleolar protein 58 (NOP58)	OTP536HD	NOP58_HUMAN	Decreases Expression	[10]
RRP15-like protein (RRP15)	OTE8CQ7K	RRP15_HUMAN	Increases Expression	[10]
Methionine-R-sulfoxide reductase B2, mitochondrial (MSRB2)	OTURGRA8	MSRB2_HUMAN	Decreases Expression	[10]
DmX-like protein 1 (DMXL1)	OTWVL31L	DMXL1_HUMAN	Decreases Expression	[10]
E3 ubiquitin-protein ligase RNF115 (RNF115)	OT35B6L5	RN115_HUMAN	Increases Expression	[10]
U6 snRNA-associated Sm-like protein LSm5 (LSM5)	OTCQHXK5	LSM5_HUMAN	Increases Expression	[10]
RNA-binding protein 7 (RBM7)	OTFIWTMF	RBM7_HUMAN	Decreases Expression	[10]
NEDD8 ultimate buster 1 (NUB1)	OTWA6RTX	NUB1_HUMAN	Increases Expression	[10]
Glypican-6 (GPC6)	OTNJBESF	GPC6_HUMAN	Increases Expression	[10]
Roundabout homolog 1 (ROBO1)	OT52UFVS	ROBO1_HUMAN	Increases Expression	[10]
Sulfotransferase 2A1 (SULT2A1)	OT0ISKQ4	ST2A1_HUMAN	Increases Metabolism	[56]
Sulfotransferase 1A1 (SULT1A1)	OT0K7JIE	ST1A1_HUMAN	Increases Metabolism	[56]
Glutathione peroxidase 1 (GPX1)	OTE2O72Q	GPX1_HUMAN	Increases ADR	[57]
Sulfotransferase 1B1 (SULT1B1)	OTH0RQYA	ST1B1_HUMAN	Increases Metabolism	[56]
Sulfotransferase 1A3 (SULT1A4)	OTHJ8WWV	ST1A3_HUMAN	Increases Metabolism	[56]
Cytochrome P450 1A2 (CYP1A2)	OTLLBX48	CP1A2_HUMAN	Affects Response To Substance	[58]

Indication(s) of Panobinostat

Disease Entry	ICD 11	Status	REF
Chronic graft versus host disease	N.A.	Approved	[3]
Lung cancer	2C25.0	Approved	[3]
Multiple myeloma	2A83	Approved	[4]
Non-small-cell lung cancer	2C25.Y	Approved	[3]
Plasma cell myeloma	2A83.1	Approved	[3]
Primary cutaneous T-cell lymphoma	N.A.	Approved	[3]
Type-2 diabetes	5A11	Phase 3	[5]
Primary myelofibrosis	2A20.2	Phase 2	[5]

Panobinostat Interacts with 1 DTT Molecule(s)

DTT Name	DTT ID	UniProt ID	Mode of Action	REF
Histone deacetylase 1 (HDAC1)	TT6R7JZ	HDAC1_HUMAN	Inhibitor	[62]

Panobinostat Interacts with 1 DTP Molecule(s)

DTP Name	DTP ID	UniProt ID	Mode of Action	REF
P-glycoprotein 1 (ABCB1)	DTUGYRD	MDR1_HUMAN	Substrate	[63]

Panobinostat Interacts with 1 DME Molecule(s)

DME Name	DME ID	UniProt ID	Mode of Action	REF
Cytochrome P450 3A4 (CYP3A4)	DE4LYSA	CP3A4_HUMAN	Metabolism	[64]

Panobinostat Interacts with 1019 DOT Molecule(s)

DOT Name	DOT ID	UniProt ID	Mode of Action	REF
Myc proto-oncogene protein (MYC)	OTPV5LUK	MYC_HUMAN	Decreases Expression	[65]
DNA-directed RNA polymerase II subunit RPB1 (POLR2A)	OTHJQ1DZ	RPB1_HUMAN	Decreases Phosphorylation	[65]
Diphosphoinositol polyphosphate phosphohydrolase NUDT4B (NUDT4)	OTA6ICI2	NUD4B_HUMAN	Increases Expression	[59]
ADP-ribose glycohydrolase MACROD2 (MACROD2)	OTNQCHC6	MACD2_HUMAN	Decreases Expression	[59]
Transmembrane protein 218 (TMEM218)	OTM46L89	TM218_HUMAN	Decreases Expression	[59]
Cadherin-like and PC-esterase domain-containing protein 1 (CPED1)	OTJJPZOZ	CPED1_HUMAN	Increases Expression	[59]
Killer cell lectin-like receptor subfamily G member 2 (KLRG2)	OTBLEXSC	KLRG2_HUMAN	Increases Expression	[59]
Protein FAM149A (FAM149A)	OTMDM0RI	F149A_HUMAN	Decreases Expression	[59]
Developmental pluripotency-associated 5 protein (DPPA5)	OTLZC371	DPPA5_HUMAN	Increases Expression	[59]
Metalloprotease TIKI2 (TRABD2B)	OTI7B18G	TIKI2_HUMAN	Increases Expression	[59]
RNA binding protein fox-1 homolog 3 (RBFOX3)	OTL0F3D6	RFOX3_HUMAN	Decreases Expression	[59]
Coiled-coil domain-containing protein 69 (CCDC69)	OT43MI0R	CCD69_HUMAN	Increases Expression	[59]
Ras association domain-containing protein 10 (RASSF10)	OTGB7EBG	RASFA_HUMAN	Decreases Expression	[59]
Very-long-chain (HACD1)	OTEC7EP7	HACD1_HUMAN	Increases Expression	[59]
NALCN channel auxiliary factor 1 (NALF1)	OT8OMCFD	NALF1_HUMAN	Decreases Expression	[59]
Rab GTPase-activating protein 1-like, isoform 10 (RABGAP1L)	OT7QO47I	RBG10_HUMAN	Increases Expression	[59]
Alternative prion protein (PRNP)	OTE85L1Q	APRIO_HUMAN	Increases Expression	[59]
Suppressyn (ERVH48-1)	OT303JGE	SUPYN_HUMAN	Increases Expression	[59]
PDZ and LIM domain protein 1 (PDLIM1)	OT4EGCPG	PDLI1_HUMAN	Increases Expression	[59]
Activator of apoptosis harakiri (HRK)	OTR4GWJ0	HRK_HUMAN	Increases Expression	[59]
Proteinase-activated receptor 3 (F2RL2)	OT982ECU	PAR3_HUMAN	Decreases Expression	[59]
Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B)	OTQ4W7MT	TR11B_HUMAN	Increases Expression	[59]
Sulfotransferase 1C2 (SULT1C2)	OT07MMZS	ST1C2_HUMAN	Increases Expression	[59]
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 (PLOD2)	OTKOZRZP	PLOD2_HUMAN	Increases Expression	[59]
Beta-1,3-N-acetylglucosaminyltransferase manic fringe (MFNG)	OTUX45ZF	MFNG_HUMAN	Decreases Expression	[59]
Podocalyxin (PODXL)	OTPNQXF3	PODXL_HUMAN	Increases Expression	[59]
E3 ubiquitin-protein ligase TRIM38 (TRIM38)	OT6SP1M9	TRI38_HUMAN	Increases Expression	[59]
Nuclear factor 1 B-type (NFIB)	OTX94PD0	NFIB_HUMAN	Increases Expression	[59]
Claudin-4 (CLDN4)	OT9C4PZ4	CLD4_HUMAN	Increases Expression	[59]
Class E basic helix-loop-helix protein 40 (BHLHE40)	OTITX14U	BHE40_HUMAN	Increases Expression	[59]
Suppressor of cytokine signaling 2 (SOCS2)	OTBPNKJQ	SOCS2_HUMAN	Increases Expression	[59]
Astrotactin-1 (ASTN1)	OT23FQIB	ASTN1_HUMAN	Decreases Expression	[59]
Suppressor of cytokine signaling 3 (SOCS3)	OTY183WJ	SOCS3_HUMAN	Decreases Expression	[59]
Cytoplasmic dynein 1 intermediate chain 1 (DYNC1I1)	OTFX1KCG	DC1I1_HUMAN	Increases Expression	[59]
Transmembrane gamma-carboxyglutamic acid protein 1 (PRRG1)	OTMH6OWG	TMG1_HUMAN	Increases Expression	[59]
Putative transcription factor Ovo-like 1 (OVOL1)	OTFJ62UI	OVOL1_HUMAN	Increases Expression	[59]
Neuropilin-1 (NRP1)	OTCGULYV	NRP1_HUMAN	Increases Expression	[59]
Tumor necrosis factor ligand superfamily member 11 (TNFSF11)	OTJEPKEQ	TNF11_HUMAN	Increases Expression	[59]
Probable proton-coupled zinc antiporter SLC30A4 (SLC30A4)	OTUYJNBS	ZNT4_HUMAN	Increases Expression	[59]
Interferon regulatory factor 6 (IRF6)	OTKJ44EV	IRF6_HUMAN	Increases Expression	[59]
Calmegin (CLGN)	OTEWVFQV	CLGN_HUMAN	Decreases Expression	[59]
Semaphorin-3E (SEMA3E)	OTD4S36H	SEM3E_HUMAN	Increases Expression	[59]
Serine/threonine-protein kinase DCLK1 (DCLK1)	OTVSPS98	DCLK1_HUMAN	Increases Expression	[59]
Angiopoietin-2 (ANGPT2)	OTEQK65P	ANGP2_HUMAN	Increases Expression	[59]
Phospholipid scramblase 1 (PLSCR1)	OTGY9B5T	PLS1_HUMAN	Increases Expression	[59]
Mitogen-activated protein kinase 13 (MAPK13)	OT0W9GE7	MK13_HUMAN	Increases Expression	[59]
DNA-directed RNA polymerase III subunit RPC7 (POLR3G)	OTU3TGQ9	RPC7_HUMAN	Increases Expression	[59]
Prosaposin receptor GPR37 (GPR37)	OTIMDDI3	GPR37_HUMAN	Increases Expression	[59]
Monocarboxylate transporter 5 (SLC16A4)	OT1YXBKC	MOT5_HUMAN	Increases Expression	[59]
TOX high mobility group box family member 3 (TOX3)	OTC9NR4W	TOX3_HUMAN	Decreases Expression	[59]
Suppressor of cytokine signaling 1 (SOCS1)	OTWA9KFU	SOCS1_HUMAN	Increases Expression	[59]
Regulator of G-protein signaling 5 (RGS5)	OTUY0Q2I	RGS5_HUMAN	Increases Expression	[59]
Leucine-rich repeat transmembrane protein FLRT2 (FLRT2)	OTGD8TID	FLRT2_HUMAN	Decreases Expression	[59]
Rho GTPase-activating protein 6 (ARHGAP6)	OTNVXXFX	RHG06_HUMAN	Increases Expression	[59]
Disintegrin and metalloproteinase domain-containing protein 12 (ADAM12)	OTZKOTDB	ADA12_HUMAN	Decreases Expression	[59]
Proline dehydrogenase 1, mitochondrial (PRODH)	OT7SQ1C7	PROD_HUMAN	Increases Expression	[59]
Transforming growth factor beta-1-induced transcript 1 protein (TGFB1I1)	OTIK337D	TGFI1_HUMAN	Increases Expression	[59]
Phospholipid-transporting ATPase IC (ATP8B1)	OTALGS63	AT8B1_HUMAN	Increases Expression	[59]
Bcl-2-like protein 11 (BCL2L11)	OTNQQWFJ	B2L11_HUMAN	Decreases Expression	[59]
Carbonic anhydrase 12 (CA12)	OT6WNFU8	CAH12_HUMAN	Increases Expression	[59]
Synaptotagmin-7 (SYT7)	OTBWAOWY	SYT7_HUMAN	Increases Expression	[59]
Protein sprouty homolog 1 (SPRY1)	OT764FXI	SPY1_HUMAN	Decreases Expression	[59]
Zinc finger protein SNAI2 (SNAI2)	OT7Y8EJ2	SNAI2_HUMAN	Increases Expression	[59]
Synaptogyrin-1 (SYNGR1)	OT0MBUK5	SNG1_HUMAN	Increases Expression	[59]
Protocadherin-7 (PCDH7)	OTP091X8	PCDH7_HUMAN	Increases Expression	[59]
Kallikrein-8 (KLK8)	OTGVGHXY	KLK8_HUMAN	Increases Expression	[59]
Phospholipid-transporting ATPase IK (ATP8B3)	OTZOGEJO	AT8B3_HUMAN	Increases Expression	[59]
Periplakin (PPL)	OTTM4WDO	PEPL_HUMAN	Increases Expression	[59]
Lymphocyte antigen 75 (LY75)	OTDHBU0N	LY75_HUMAN	Increases Expression	[59]
BMP/retinoic acid-inducible neural-specific protein 1 (BRINP1)	OTEUVSCP	BRNP1_HUMAN	Increases Expression	[59]
Homeobox protein DLX-3 (DLX3)	OTARP5SQ	DLX3_HUMAN	Increases Expression	[59]
Plexin-C1 (PLXNC1)	OTJ5XKYY	PLXC1_HUMAN	Decreases Expression	[59]
Gremlin-1 (GREM1)	OTCK4IGV	GREM1_HUMAN	Increases Expression	[59]
Cyclin-T2 (CCNT2)	OTBDRH1J	CCNT2_HUMAN	Decreases Expression	[59]
Histone H2B type 1-K (H2BC12)	OTQ8V0KG	H2B1K_HUMAN	Decreases Expression	[59]
Growth arrest-specific protein 7 (GAS7)	OT0M5TNY	GAS7_HUMAN	Increases Expression	[59]
Protein diaphanous homolog 2 (DIAPH2)	OTBEYFEZ	DIAP2_HUMAN	Increases Expression	[59]
Inward rectifier potassium channel 13 (KCNJ13)	OTG1CNND	KCJ13_HUMAN	Decreases Expression	[59]
Plexin-A2 (PLXNA2)	OTNNBJMQ	PLXA2_HUMAN	Increases Expression	[59]
Frizzled-7 (FZD7)	OTTK3F6E	FZD7_HUMAN	Increases Expression	[59]
Slit homolog 1 protein (SLIT1)	OT35RBNT	SLIT1_HUMAN	Increases Expression	[59]
Slit homolog 3 protein (SLIT3)	OTU8MKEU	SLIT3_HUMAN	Increases Expression	[59]
Probable phospholipid-transporting ATPase IIA (ATP9A)	OT328F1L	ATP9A_HUMAN	Decreases Expression	[59]
Microfibrillar-associated protein 3-like (MFAP3L)	OTNMHSAH	MFA3L_HUMAN	Decreases Expression	[59]
Protein cordon-bleu (COBL)	OTTB4VFQ	COBL_HUMAN	Increases Expression	[59]
Astrotactin-2 (ASTN2)	OTF0W2FJ	ASTN2_HUMAN	Increases Expression	[59]
Calcium-transporting ATPase type 2C member 2 (ATP2C2)	OTGIHTYQ	AT2C2_HUMAN	Increases Expression	[59]
Growth arrest and DNA damage-inducible protein GADD45 beta (GADD45B)	OTL9I7LO	GA45B_HUMAN	Increases Expression	[59]
Core histone macro-H2A.1 (MACROH2A1)	OTV2DQDD	H2AY_HUMAN	Decreases Expression	[59]
Filamin-B (FLNB)	OTPCOYL6	FLNB_HUMAN	Increases Expression	[59]
Large neutral amino acids transporter small subunit 3 (SLC43A1)	OTQJQY3S	LAT3_HUMAN	Increases Expression	[59]
Transforming acidic coiled-coil-containing protein 1 (TACC1)	OTGX20TE	TACC1_HUMAN	Increases Expression	[59]
NADH dehydrogenase 1 beta subcomplex subunit 1 (NDUFB1)	OTLMT95K	NDUB1_HUMAN	Decreases Expression	[59]
Glypican-4 (GPC4)	OTUJ14DW	GPC4_HUMAN	Decreases Expression	[59]
Disabled homolog 1 (DAB1)	OTPL9MA3	DAB1_HUMAN	Decreases Expression	[59]
Src kinase-associated phosphoprotein 2 (SKAP2)	OTSF44KP	SKAP2_HUMAN	Increases Expression	[59]
Forkhead box protein H1 (FOXH1)	OTEXJ9SL	FOXH1_HUMAN	Increases Expression	[59]
PR domain zinc finger protein 1 (PRDM1)	OTQLSVBS	PRDM1_HUMAN	Increases Expression	[59]
Scrapie-responsive protein 1 (SCRG1)	OTBE7V0P	SCRG1_HUMAN	Increases Expression	[59]
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial (SLC25A12)	OTB4YBVT	S2512_HUMAN	Increases Expression	[59]
Leukocyte cell-derived chemotaxin 1 (CNMD)	OTHND8EL	CNMD_HUMAN	Increases Expression	[59]
Short-chain dehydrogenase/reductase 3 (DHRS3)	OTSK1DTP	DHRS3_HUMAN	Increases Expression	[59]
Serine/threonine-protein kinase PAK 3 (PAK3)	OT80M3BV	PAK3_HUMAN	Decreases Expression	[59]
Lysozyme-like protein 6 (LYZL6)	OT6XS67M	LYZL6_HUMAN	Increases Expression	[59]
Retinal dehydrogenase 2 (ALDH1A2)	OTJB560Z	AL1A2_HUMAN	Decreases Expression	[59]
Slit homolog 2 protein (SLIT2)	OTLS2RJ4	SLIT2_HUMAN	Increases Expression	[59]
Nucleolar protein 4 (NOL4)	OTWI587R	NOL4_HUMAN	Decreases Expression	[59]
Kelch repeat and BTB domain-containing protein 11 (KBTBD11)	OTBOY3WH	KBTBB_HUMAN	Decreases Expression	[59]
Unconventional myosin-Id (MYO1D)	OTP2RGPN	MYO1D_HUMAN	Increases Expression	[59]
Protein transport protein Sec24D (SEC24D)	OTXR3KC9	SC24D_HUMAN	Increases Expression	[59]
Neurofascin (NFASC)	OTBDUXZT	NFASC_HUMAN	Decreases Expression	[59]
Thymocyte selection-associated high mobility group box protein TOX (TOX)	OTE8BL5Z	TOX_HUMAN	Increases Expression	[59]
Glutaminase kidney isoform, mitochondrial (GLS)	OTGOZG2M	GLSK_HUMAN	Increases Expression	[59]
Rho-related BTB domain-containing protein 3 (RHOBTB3)	OT1BFKPH	RHBT3_HUMAN	Increases Expression	[59]
Serine protease 23 (PRSS23)	OT6DQAM1	PRS23_HUMAN	Decreases Expression	[59]
Peripheral-type benzodiazepine receptor-associated protein 1 (TSPOAP1)	OTAM8SGF	RIMB1_HUMAN	Decreases Expression	[59]
Chondroitin sulfate proteoglycan 5 (CSPG5)	OTXFEBWR	CSPG5_HUMAN	Decreases Expression	[59]
Protocadherin-8 (PCDH8)	OTDDOQM2	PCDH8_HUMAN	Increases Expression	[59]
Histone acetyltransferase KAT7 (KAT7)	OTUN98IC	KAT7_HUMAN	Decreases Expression	[59]
Ly6/PLAUR domain-containing protein 3 (LYPD3)	OTLR2PYX	LYPD3_HUMAN	Increases Expression	[59]
Homeobox protein SIX3 (SIX3)	OTP5E3VU	SIX3_HUMAN	Decreases Expression	[59]
Neuroendocrine secretory protein 55 (GNAS)	OTMH8BKJ	GNAS3_HUMAN	Increases Expression	[59]
Claudin-7 (CLDN7)	OTNE0XHQ	CLD7_HUMAN	Increases Expression	[59]
Homeobox protein SIX6 (SIX6)	OTD1RD9D	SIX6_HUMAN	Decreases Expression	[59]
Protein phosphatase 1 regulatory subunit 3D (PPP1R3D)	OTZNC7R2	PPR3D_HUMAN	Increases Expression	[59]
C-X-C motif chemokine 14 (CXCL14)	OTM189TA	CXL14_HUMAN	Increases Expression	[59]
Fibroblast growth factor 19 (FGF19)	OT2DVJWY	FGF19_HUMAN	Increases Expression	[59]
Heat shock 70 kDa protein 4L (HSPA4L)	OT181WZB	HS74L_HUMAN	Increases Expression	[59]
TBC1 domain family member 8 (TBC1D8)	OT2011SS	TBCD8_HUMAN	Decreases Expression	[59]
BAG family molecular chaperone regulator 2 (BAG2)	OTI6LD27	BAG2_HUMAN	Increases Expression	[59]
Claudin-1 (CLDN1)	OT27KV99	CLD1_HUMAN	Increases Expression	[59]
Histone-lysine N-methyltransferase NSD2 (NSD2)	OTQ6SW4R	NSD2_HUMAN	Decreases Expression	[59]
Purine nucleoside phosphorylase (PNP)	OTO5NIJ2	PNPH_HUMAN	Increases Expression	[59]
Urokinase-type plasminogen activator (PLAU)	OTX0QGKK	UROK_HUMAN	Increases Expression	[59]
Tissue-type plasminogen activator (PLAT)	OTQPDNAB	TPA_HUMAN	Increases Expression	[59]
Adenosine deaminase (ADA)	OTOX2872	ADA_HUMAN	Decreases Expression	[59]
Argininosuccinate synthase (ASS1)	OT4ZMG0Q	ASSY_HUMAN	Increases Expression	[59]
Serine protease inhibitor Kazal-type 1 (SPINK1)	OTSUVAL2	ISK1_HUMAN	Increases Expression	[59]
Pro-epidermal growth factor (EGF)	OTANRJ0L	EGF_HUMAN	Decreases Expression	[59]
Proenkephalin-B (PDYN)	OTEJ6430	PDYN_HUMAN	Increases Expression	[59]
Calcitonin (CALCA)	OTZ11LHB	CALC_HUMAN	Increases Expression	[59]
Pro-neuropeptide Y (NPY)	OT4ICV3P	NPY_HUMAN	Increases Expression	[59]
Insulin-like growth factor II (IGF2)	OTJ4O6MW	IGF2_HUMAN	Increases Expression	[59]
Alpha-1-acid glycoprotein 1 (ORM1)	OTZKSBRE	A1AG1_HUMAN	Decreases Expression	[59]
Annexin A1 (ANXA1)	OT5OFDJC	ANXA1_HUMAN	Increases Expression	[59]
Platelet-derived growth factor subunit A (PDGFA)	OTCMZ0W8	PDGFA_HUMAN	Increases Expression	[59]
Ornithine aminotransferase, mitochondrial (OAT)	OTEKO8CT	OAT_HUMAN	Increases Expression	[59]
N-myc proto-oncogene protein (MYCN)	OTWD33K1	MYCN_HUMAN	Increases Expression	[59]
HLA class II histocompatibility antigen gamma chain (CD74)	OTO16X4Q	HG2A_HUMAN	Increases Expression	[59]
Protein S100-B (S100B)	OTHHDS33	S100B_HUMAN	Increases Expression	[59]
Cytochrome P450 1A1 (CYP1A1)	OTE4EFH8	CP1A1_HUMAN	Increases Expression	[59]
Glycophorin-C (GYPC)	OTOEDR7O	GLPC_HUMAN	Increases Expression	[59]
Endothelin-1 (EDN1)	OTZCACEG	EDN1_HUMAN	Increases Expression	[59]
Intercellular adhesion molecule 1 (ICAM1)	OTTOIX77	ICAM1_HUMAN	Increases Expression	[59]
Transcription factor Jun (JUN)	OTCYBO6X	JUN_HUMAN	Increases Expression	[59]
Fatty acid-binding protein, heart (FABP3)	OT562DA1	FABPH_HUMAN	Increases Expression	[59]
Transcription factor AP-2-alpha (TFAP2A)	OTMYT3NK	AP2A_HUMAN	Increases Expression	[59]
Protein kinase C beta type (PRKCB)	OTYQ0656	KPCB_HUMAN	Increases Expression	[59]
Keratin, type I cytoskeletal 18 (KRT18)	OTVLQFIP	K1C18_HUMAN	Increases Expression	[59]
Keratin, type II cytoskeletal 8 (KRT8)	OTTM4X11	K2C8_HUMAN	Increases Expression	[59]
Beta-crystallin A3 (CRYBA1)	OT8617WJ	CRBA1_HUMAN	Decreases Expression	[59]
Collagen alpha-2(V) chain (COL5A2)	OT5VOSQE	CO5A2_HUMAN	Increases Expression	[59]
Protein S100-A6 (S100A6)	OTHHPZQ8	S10A6_HUMAN	Increases Expression	[59]
Neurofilament light polypeptide (NEFL)	OTQESJV4	NFL_HUMAN	Increases Expression	[59]
Neurofilament medium polypeptide (NEFM)	OT8VCBNF	NFM_HUMAN	Increases Expression	[59]
Annexin A2 (ANXA2)	OTFNS0CC	ANXA2_HUMAN	Increases Expression	[59]
Tyrosine-protein kinase Lyn (LYN)	OTP686K2	LYN_HUMAN	Increases Expression	[59]
Collagen alpha-2(I) chain (COL1A2)	OTY7G382	CO1A2_HUMAN	Increases Expression	[59]
Tumor necrosis factor receptor superfamily member 16 (NGFR)	OTPKSM49	TNR16_HUMAN	Increases Expression	[59]
Complement decay-accelerating factor (CD55)	OTZ3HWTO	DAF_HUMAN	Increases Expression	[59]
Asparagine synthetase (ASNS)	OT8R922G	ASNS_HUMAN	Increases Expression	[59]
Retinol-binding protein 1 (RBP1)	OTRP1MFC	RET1_HUMAN	Increases Expression	[59]
Heme oxygenase 1 (HMOX1)	OTC1W6UX	HMOX1_HUMAN	Increases Expression	[59]
Tumor-associated calcium signal transducer 2 (TACSTD2)	OTLSZR00	TACD2_HUMAN	Increases Expression	[59]
Protein FAM200B (FAM200B)	OTQMCR8C	F200B_HUMAN	Decreases Expression	[59]
Apelin receptor early endogenous ligand (APELA)	OTYY0P69	ELA_HUMAN	Increases Expression	[59]
Apoptosis regulator Bcl-2 (BCL2)	OT9DVHC0	BCL2_HUMAN	Decreases Expression	[59]
Osteopontin (SPP1)	OTJGC23Y	OSTP_HUMAN	Increases Expression	[59]
COUP transcription factor 1 (NR2F1)	OTGWZWYL	COT1_HUMAN	Increases Expression	[59]
Chromogranin-A (CHGA)	OTXYX5JH	CMGA_HUMAN	Increases Expression	[59]
Tissue factor pathway inhibitor (TFPI)	OTA0FX16	TFPI1_HUMAN	Increases Expression	[59]
Mast/stem cell growth factor receptor Kit (KIT)	OTHUY3VZ	KIT_HUMAN	Increases Expression	[59]
Retinoic acid receptor beta (RARB)	OT367U3E	RARB_HUMAN	Increases Expression	[59]
Thyroid hormone receptor beta (THRB)	OTBBIRHZ	THB_HUMAN	Increases Expression	[59]
Clusterin (CLU)	OTQGG0JM	CLUS_HUMAN	Increases Expression	[59]
Hyaluronan and proteoglycan link protein 1 (HAPLN1)	OTXWR9TJ	HPLN1_HUMAN	Increases Expression	[59]
Microtubule-associated protein 2 (MAP2)	OT6UYT3X	MTAP2_HUMAN	Increases Expression	[59]
Solute carrier family 2, facilitated glucose transporter member 3 (SLC2A3)	OT2HZK5M	GTR3_HUMAN	Increases Expression	[59]
Serine/threonine-protein kinase pim-1 (PIM1)	OTWEKXTU	PIM1_HUMAN	Increases Expression	[59]
Collagen alpha-1(VI) chain (COL6A1)	OTYKSCOB	CO6A1_HUMAN	Increases Expression	[59]
Collagen alpha-3(VI) chain (COL6A3)	OTAS6R6I	CO6A3_HUMAN	Increases Expression	[59]
Annexin A3 (ANXA3)	OTDD8OI7	ANXA3_HUMAN	Increases Expression	[59]
Bone morphogenetic protein 2 (BMP2)	OT23T37S	BMP2_HUMAN	Increases Expression	[59]
Bone morphogenetic protein 4 (BMP4)	OTPZMDFH	BMP4_HUMAN	Increases Expression	[59]
Cadherin-1 (CDH1)	OTFJMXPM	CADH1_HUMAN	Increases Expression	[59]
Interferon-induced transmembrane protein 1 (IFITM1)	OTECO1G8	IFM1_HUMAN	Increases Expression	[59]
Gamma-interferon-inducible lysosomal thiol reductase (IFI30)	OT9DERT1	GILT_HUMAN	Increases Expression	[59]
Protein Cripto (CRIPTO)	OT46DZXJ	TDGF1_HUMAN	Increases Expression	[59]
Lysosome-associated membrane glycoprotein 2 (LAMP2)	OTLUGEJC	LAMP2_HUMAN	Increases Expression	[59]
Phospholipase A2, membrane associated (PLA2G2A)	OT1NY7BF	PA2GA_HUMAN	Increases Expression	[59]
Pyruvate kinase PKM (PKM)	OTLHHMC2	KPYM_HUMAN	Increases Expression	[59]
Protein C-ets-1 (ETS1)	OT4LVGDN	ETS1_HUMAN	Increases Expression	[59]
Ras-related C3 botulinum toxin substrate 2 (RAC2)	OTAOHFNH	RAC2_HUMAN	Increases Expression	[59]
Prostatic acid phosphatase (ACP3)	OTSIM0YG	PPAP_HUMAN	Increases Expression	[59]
Ezrin (EZR)	OTHBPF1Z	EZRI_HUMAN	Increases Expression	[59]
NAD(P)H dehydrogenase 1 (NQO1)	OTZGGIVK	NQO1_HUMAN	Increases Expression	[59]
CD44 antigen (CD44)	OT9TTJ41	CD44_HUMAN	Increases Expression	[59]
Ribosyldihydronicotinamide dehydrogenase (NQO2)	OTGDAJRZ	NQO2_HUMAN	Increases Expression	[59]
Platelet-derived growth factor receptor alpha (PDGFRA)	OTDJXUCN	PGFRA_HUMAN	Increases Expression	[59]
Solute carrier family 25 member 16 (SLC25A16)	OTTTUL91	GDC_HUMAN	Increases Expression	[59]
Epithelial cell adhesion molecule (EPCAM)	OTHBZK5X	EPCAM_HUMAN	Increases Expression	[59]
Carboxypeptidase E (CPE)	OTXNTV79	CBPE_HUMAN	Increases Expression	[59]
Protein kinase C alpha type (PRKCA)	OT5UWNRD	KPCA_HUMAN	Increases Expression	[59]
Atrial natriuretic peptide receptor 3 (NPR3)	OT6MQP3A	ANPRC_HUMAN	Increases Expression	[59]
cAMP-dependent protein kinase catalytic subunit alpha (PRKACA)	OTAKDCMR	KAPCA_HUMAN	Increases Expression	[59]
CCAAT/enhancer-binding protein beta (CEBPB)	OTM9MQIA	CEBPB_HUMAN	Increases Expression	[59]
Neuromodulin (GAP43)	OT2OTGGV	NEUM_HUMAN	Increases Expression	[59]
Galectin-3 (LGALS3)	OTYQT0ZI	LEG3_HUMAN	Increases Expression	[59]
Insulin-like growth factor-binding protein 3 (IGFBP3)	OTIX63TX	IBP3_HUMAN	Decreases Expression	[59]
Vascular endothelial growth factor receptor 1 (FLT1)	OTT0OGYS	VGFR1_HUMAN	Increases Expression	[59]
Bone morphogenetic protein 7 (BMP7)	OTYATP2K	BMP7_HUMAN	Increases Expression	[59]
Integrin beta-5 (ITGB5)	OT21MF51	ITB5_HUMAN	Decreases Expression	[59]
Pituitary adenylate cyclase-activating polypeptide (ADCYAP1)	OT0LQH93	PACA_HUMAN	Increases Expression	[59]
Cyclic AMP-dependent transcription factor ATF-3 (ATF3)	OTC1UOHP	ATF3_HUMAN	Increases Expression	[59]
Cadherin-2 (CDH2)	OTH0Y56P	CADH2_HUMAN	Decreases Expression	[59]
Hexokinase-1 (HK1)	OTMPHE8O	HXK1_HUMAN	Increases Expression	[59]
Alpha-1-acid glycoprotein 2 (ORM2)	OTRJGZP8	A1AG2_HUMAN	Decreases Expression	[59]
Complement receptor type 2 (CR2)	OT90NDLY	CR2_HUMAN	Increases Expression	[59]
Serine protease inhibitor Kazal-type 2 (SPINK2)	OTSFBT0G	ISK2_HUMAN	Increases Expression	[59]
POU domain, class 3, transcription factor 3 (POU3F3)	OT6BBXPD	PO3F3_HUMAN	Increases Expression	[59]
Muscarinic acetylcholine receptor M3 (CHRM3)	OTKSD095	ACM3_HUMAN	Increases Expression	[59]
Protachykinin-1 (TAC1)	OTM842YW	TKN1_HUMAN	Increases Expression	[59]
Serine/threonine-protein kinase MAK (MAK)	OTEU2G41	MAK_HUMAN	Decreases Expression	[59]
Ephrin-A1 (EFNA1)	OTU2NUA2	EFNA1_HUMAN	Increases Expression	[59]
Neurofibromin (NF1)	OTC29NHH	NF1_HUMAN	Decreases Expression	[59]
Kit ligand (KITLG)	OTB9AVQ4	SCF_HUMAN	Increases Expression	[59]
Diamine acetyltransferase 1 (SAT1)	OT52AU22	SAT1_HUMAN	Increases Expression	[59]
Receptor tyrosine-protein kinase erbB-3 (ERBB3)	OTRSST0A	ERBB3_HUMAN	Increases Expression	[59]
CD9 antigen (CD9)	OT2184XU	CD9_HUMAN	Increases Expression	[59]
Bone morphogenetic protein 5 (BMP5)	OTC0Y6E0	BMP5_HUMAN	Increases Expression	[59]
Alpha-(1,3)-fucosyltransferase 4 (FUT4)	OTIBXRTL	FUT4_HUMAN	Increases Expression	[59]
Cadherin-3 (CDH3)	OTKNLQU7	CADH3_HUMAN	Increases Expression	[59]
Fibroblast growth factor receptor 3 (FGFR3)	OTSAXDIL	FGFR3_HUMAN	Increases Expression	[59]
Calretinin (CALB2)	OTSNMCG9	CALB2_HUMAN	Increases Expression	[59]
Carbonic anhydrase 4 (CA4)	OT3K93LZ	CAH4_HUMAN	Decreases Expression	[59]
Prostaglandin G/H synthase 1 (PTGS1)	OTHCRLEC	PGH1_HUMAN	Decreases Expression	[59]
Peptidyl-prolyl cis-trans isomerase B (PPIB)	OTLPH6KN	PPIB_HUMAN	Increases Expression	[59]
Colorectal mutant cancer protein (MCC)	OTQVI1EM	CRCM_HUMAN	Increases Expression	[59]
Paired box protein Pax-7 (PAX7)	OTDMQRPO	PAX7_HUMAN	Increases Expression	[59]
Paired box protein Pax-3 (PAX3)	OTN5PJZV	PAX3_HUMAN	Increases Expression	[59]
Endothelial transcription factor GATA-2 (GATA2)	OTBP2QQ2	GATA2_HUMAN	Increases Expression	[59]
Trans-acting T-cell-specific transcription factor GATA-3 (GATA3)	OTGP7D5Y	GATA3_HUMAN	Increases Expression	[59]
Laminin subunit alpha-2 (LAMA2)	OTFROQWE	LAMA2_HUMAN	Increases Expression	[59]
COUP transcription factor 2 (NR2F2)	OTJFS67N	COT2_HUMAN	Decreases Expression	[59]
Endothelin receptor type B (EDNRB)	OTLLZV3P	EDNRB_HUMAN	Increases Expression	[59]
Protein kinase C eta type (PRKCH)	OTC498N5	KPCL_HUMAN	Increases Expression	[59]
Signal transducer CD24 (CD24)	OT7CODJ4	CD24_HUMAN	Increases Expression	[59]
Endothelin-1 receptor (EDNRA)	OTK9T5O3	EDNRA_HUMAN	Increases Expression	[59]
Atypical chemokine receptor 3 (ACKR3)	OTA6GA4F	ACKR3_HUMAN	Increases Expression	[59]
Myelin protein P0 (MPZ)	OTAR2YXH	MYP0_HUMAN	Increases Expression	[59]
Rhombotin-2 (LMO2)	OTCC370G	RBTN2_HUMAN	Decreases Expression	[59]
Neuropeptide Y receptor type 1 (NPY1R)	OT5DA9DY	NPY1R_HUMAN	Decreases Expression	[59]
Collagen alpha-3(V) chain (COL5A3)	OTCGC4DM	CO5A3_HUMAN	Increases Expression	[59]
Paired box protein Pax-6 (PAX6)	OTOC9876	PAX6_HUMAN	Decreases Expression	[59]
Protein S100-A4 (S100A4)	OTLRGFSQ	S10A4_HUMAN	Increases Expression	[59]
Threonine--tRNA ligase 1, cytoplasmic (TARS1)	OT0PWST5	SYTC_HUMAN	Increases Expression	[59]
Serum paraoxonase/arylesterase 1 (PON1)	OTD0Z2XO	PON1_HUMAN	Decreases Expression	[59]
Homeobox protein MSX-1 (MSX1)	OT5U41ZP	MSX1_HUMAN	Increases Expression	[59]
Gamma-aminobutyric acid receptor subunit beta-3 (GABRB3)	OT80C3D4	GBRB3_HUMAN	Increases Expression	[59]
Ephrin type-A receptor 3 (EPHA3)	OTZJF3ML	EPHA3_HUMAN	Increases Expression	[59]
Ephrin type-B receptor 2 (EPHB2)	OT8VZ6C5	EPHB2_HUMAN	Decreases Expression	[59]
Cellular retinoic acid-binding protein 2 (CRABP2)	OTY01V9G	RABP2_HUMAN	Increases Expression	[59]
GTP cyclohydrolase 1 feedback regulatory protein (GCHFR)	OTEOT8GI	GFRP_HUMAN	Increases Expression	[59]
Translocator protein (TSPO)	OTSU7ESK	TSPO_HUMAN	Increases Expression	[59]
CAMPATH-1 antigen (CD52)	OT02LDQN	CD52_HUMAN	Increases Expression	[59]
Fibroblast growth factor 9 (FGF9)	OT2SKDGM	FGF9_HUMAN	Decreases Expression	[59]
Syndecan-4 (SDC4)	OTKUVUGZ	SDC4_HUMAN	Increases Expression	[59]
14-3-3 protein sigma (SFN)	OTLJCZ1U	1433S_HUMAN	Increases Expression	[59]
Protein S100-A11 (S100A11)	OTI57KDN	S10AB_HUMAN	Increases Expression	[59]
Neural cell adhesion molecule L1 (L1CAM)	OTNWAQ4Y	L1CAM_HUMAN	Increases Expression	[59]
Gastrin/cholecystokinin type B receptor (CCKBR)	OTQSNXOI	GASR_HUMAN	Decreases Expression	[59]
ETS-related transcription factor Elf-1 (ELF1)	OTV5LKIA	ELF1_HUMAN	Increases Expression	[59]
Intercellular adhesion molecule 3 (ICAM3)	OTTZ5A5D	ICAM3_HUMAN	Increases Expression	[59]
Long-chain-fatty-acid--CoA ligase 1 (ACSL1)	OTB06ESI	ACSL1_HUMAN	Increases Expression	[59]
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA (MAN1A1)	OT6LIGJP	MA1A1_HUMAN	Increases Expression	[59]
Carbonic anhydrase-related protein (CA8)	OT9Y8GA8	CAH8_HUMAN	Increases Expression	[59]
Prostaglandin E2 receptor EP4 subtype (PTGER4)	OT2GBV06	PE2R4_HUMAN	Increases Expression	[59]
Thrombospondin-2 (THBS2)	OTXET551	TSP2_HUMAN	Increases Expression	[59]
Homeobox protein MSX-2 (MSX2)	OT1WDKE1	MSX2_HUMAN	Increases Expression	[59]
Fibrillin-1 (FBN1)	OTYCJT63	FBN1_HUMAN	Decreases Expression	[59]
Transcription factor SOX-11 (SOX11)	OT4LG7LA	SOX11_HUMAN	Decreases Expression	[59]
Phosphoglucomutase-1 (PGM1)	OT3VM4JX	PGM1_HUMAN	Increases Expression	[59]
Pigment epithelium-derived factor (SERPINF1)	OTWZH98J	PEDF_HUMAN	Decreases Expression	[59]
Amiloride-sensitive sodium channel subunit alpha (SCNN1A)	OTE2KVZV	SCNNA_HUMAN	Increases Expression	[59]
Transgelin-2 (TAGLN2)	OTUXZGDQ	TAGL2_HUMAN	Increases Expression	[59]
Kappa-type opioid receptor (OPRK1)	OTXCZF4L	OPRK_HUMAN	Decreases Expression	[59]
Transcription factor SOX-3 (SOX3)	OT1CRCOB	SOX3_HUMAN	Decreases Expression	[59]
Pituitary adenylate cyclase-activating polypeptide type I receptor (ADCYAP1R1)	OTNBHULA	PACR_HUMAN	Increases Expression	[59]
ETS domain-containing protein Elk-3 (ELK3)	OTBM9BHT	ELK3_HUMAN	Increases Expression	[59]
Signal transducer and activator of transcription 6 (STAT6)	OTCKMP49	STAT6_HUMAN	Increases Expression	[59]
Glutamate receptor 3 (GRIA3)	OT34CNBR	GRIA3_HUMAN	Decreases Expression	[59]
Leukemia inhibitory factor receptor (LIFR)	OT36W9O5	LIFR_HUMAN	Increases Expression	[59]
C-X-C motif chemokine 5 (CXCL5)	OTZOUPCA	CXCL5_HUMAN	Increases Expression	[59]
Excitatory amino acid transporter 1 (SLC1A3)	OTILR60R	EAA1_HUMAN	Increases Expression	[59]
Netrin receptor DCC (DCC)	OT2C1SHW	DCC_HUMAN	Increases Expression	[59]
Tyrosine-protein kinase SYK (SYK)	OTQID87L	KSYK_HUMAN	Increases Expression	[59]
Lysophosphatidic acid receptor 6 (LPAR6)	OT4BY3W4	LPAR6_HUMAN	Increases Expression	[59]
Transcription factor GATA-4 (GATA4)	OTQHWAZG	GATA4_HUMAN	Decreases Expression	[59]
Peptidyl-prolyl cis-trans isomerase C (PPIC)	OTY5Q42N	PPIC_HUMAN	Increases Expression	[59]
Radiation-inducible immediate-early gene IEX-1 (IER3)	OTZJI5FZ	IEX1_HUMAN	Increases Expression	[59]
Ras GTPase-activating-like protein IQGAP1 (IQGAP1)	OTZRWTGA	IQGA1_HUMAN	Increases Expression	[59]
Cytosolic phospholipase A2 (PLA2G4A)	OTE70SOT	PA24A_HUMAN	Increases Expression	[59]
Gamma-aminobutyric acid receptor subunit beta-2 (GABRB2)	OTAOZIGX	GBRB2_HUMAN	Increases Expression	[59]
Retinaldehyde dehydrogenase 3 (ALDH1A3)	OT1C9NKQ	AL1A3_HUMAN	Increases Expression	[59]
DNA-binding protein inhibitor ID-4 (ID4)	OTPMJ39I	ID4_HUMAN	Increases Expression	[59]
Sodium- and chloride-dependent creatine transporter 1 (SLC6A8)	OT88C8JA	SC6A8_HUMAN	Decreases Expression	[59]
Stromal cell-derived factor 1 (CXCL12)	OT2QX5LL	SDF1_HUMAN	Increases Expression	[59]
Tissue factor pathway inhibitor 2 (TFPI2)	OTZCRWOR	TFPI2_HUMAN	Increases Expression	[59]
Transcription factor SOX-2 (SOX2)	OTFAWCAU	SOX2_HUMAN	Decreases Expression	[59]
Transcription factor SOX-9 (SOX9)	OTVDJFGN	SOX9_HUMAN	Increases Expression	[59]
Potassium voltage-gated channel subfamily C member 1 (KCNC1)	OTW9WF1J	KCNC1_HUMAN	Decreases Expression	[59]
Nuclear receptor-interacting protein 1 (NRIP1)	OTIZOJQV	NRIP1_HUMAN	Increases Expression	[59]
Neuropeptide Y receptor type 2 (NPY2R)	OTEWQJ6B	NPY2R_HUMAN	Decreases Expression	[59]
Protein ERGIC-53 (LMAN1)	OTYHKDEO	LMAN1_HUMAN	Decreases Expression	[59]
Beta-arrestin-1 (ARRB1)	OT2NJS37	ARRB1_HUMAN	Increases Expression	[59]
CCAAT/enhancer-binding protein delta (CEBPD)	OTNBIPMY	CEBPD_HUMAN	Increases Expression	[59]
Selenoprotein P (SELENOP)	OT02B8IR	SEPP1_HUMAN	Increases Expression	[59]
Histamine N-methyltransferase (HNMT)	OT9F303M	HNMT_HUMAN	Increases Expression	[59]
Isocitrate dehydrogenase subunit alpha, mitochondrial (IDH3A)	OT5QQB5L	IDH3A_HUMAN	Increases Expression	[59]
Motor neuron and pancreas homeobox protein 1 (MNX1)	OTXP9FH1	MNX1_HUMAN	Increases Expression	[59]
Homeobox protein MOX-1 (MEOX1)	OTJEMT2D	MEOX1_HUMAN	Increases Expression	[59]
Sulfotransferase 1A2 (SULT1A2)	OT7EJ6LQ	ST1A2_HUMAN	Increases Expression	[59]
Matrix metalloproteinase-14 (MMP14)	OT9C197Z	MMP14_HUMAN	Increases Expression	[59]
Protoporphyrinogen oxidase (PPOX)	OT75GZ3K	PPOX_HUMAN	Decreases Expression	[59]
Serpin B9 (SERPINB9)	OTJ811IF	SPB9_HUMAN	Increases Expression	[59]
LIM/homeobox protein Lhx2 (LHX2)	OTK61NP8	LHX2_HUMAN	Decreases Expression	[59]
ETS translocation variant 1 (ETV1)	OT6PMJIK	ETV1_HUMAN	Decreases Expression	[59]
Amiloride-sensitive sodium channel subunit gamma (SCNN1G)	OTSJYQVQ	SCNNG_HUMAN	Increases Expression	[59]
Probable global transcription activator SNF2L2 (SMARCA2)	OTSGJ8SV	SMCA2_HUMAN	Increases Expression	[59]
Glypican-3 (GPC3)	OTWS8WSW	GPC3_HUMAN	Decreases Expression	[59]
Ephrin-A5 (EFNA5)	OTOH4DRR	EFNA5_HUMAN	Decreases Expression	[59]
Stanniocalcin-1 (STC1)	OTGVVXYF	STC1_HUMAN	Increases Expression	[59]
Homeobox protein GBX-2 (GBX2)	OTW0ZI4D	GBX2_HUMAN	Increases Expression	[59]
Beta-crystallin A4 (CRYBA4)	OTQJ5XGE	CRBA4_HUMAN	Decreases Expression	[59]
Integrin alpha-8 (ITGA8)	OTBH8WFD	ITA8_HUMAN	Increases Expression	[59]
Mitogen-activated protein kinase 10 (MAPK10)	OTC46VX1	MK10_HUMAN	Decreases Expression	[59]
Calcipressin-1 (RCAN1)	OT1MVXC7	RCAN1_HUMAN	Increases Expression	[59]
Monocarboxylate transporter 1 (SLC16A1)	OTW1UTZ7	MOT1_HUMAN	Increases Expression	[59]
Voltage-dependent calcium channel subunit alpha-2/delta-1 (CACNA2D1)	OT5YLZIH	CA2D1_HUMAN	Increases Expression	[59]
Ephrin type-A receptor 4 (EPHA4)	OT3AMK0C	EPHA4_HUMAN	Decreases Expression	[59]
Paired mesoderm homeobox protein 1 (PRRX1)	OTTZK5G8	PRRX1_HUMAN	Increases Expression	[59]
Tyrosine-protein phosphatase non-receptor type 5 (PTPN5)	OT2H1KDK	PTN5_HUMAN	Decreases Expression	[59]
Epithelial membrane protein 1 (EMP1)	OTSZHUHQ	EMP1_HUMAN	Increases Expression	[59]
Fibroblast growth factor 8 (FGF8)	OTFU0IUW	FGF8_HUMAN	Decreases Expression	[59]
Proteinase-activated receptor 2 (F2RL1)	OTMRMJ8N	PAR2_HUMAN	Increases Expression	[59]
Cadherin-8 (CDH8)	OTS3SRZ6	CADH8_HUMAN	Decreases Expression	[59]
Homeobox protein DLX-6 (DLX6)	OT0FIJHY	DLX6_HUMAN	Decreases Expression	[59]
Transcription factor SOX-10 (SOX10)	OTF25ULQ	SOX10_HUMAN	Increases Expression	[59]
Neurotrypsin (PRSS12)	OT1MYL3L	NETR_HUMAN	Increases Expression	[59]
Claudin-6 (CLDN6)	OTEN8ID2	CLD6_HUMAN	Increases Expression	[59]
Transcription factor SOX-8 (SOX8)	OTEJXYZM	SOX8_HUMAN	Increases Expression	[59]
Potassium channel subfamily K member 10 (KCNK10)	OT93GC7V	KCNKA_HUMAN	Decreases Expression	[59]
Inhibin beta E chain (INHBE)	OTOI2NYG	INHBE_HUMAN	Increases Expression	[59]
Myelin proteolipid protein (PLP1)	OT8CM9CX	MYPR_HUMAN	Increases Expression	[59]
Synaptosomal-associated protein 25 (SNAP25)	OTUIQ81Q	SNP25_HUMAN	Increases Expression	[59]
Protein S100-A10 (S100A10)	OTI71243	S10AA_HUMAN	Increases Expression	[59]
Somatostatin (SST)	OTY75GQH	SMS_HUMAN	Increases Expression	[59]
Rho-related GTP-binding protein RhoE (RND3)	OTXMXPIH	RND3_HUMAN	Increases Expression	[59]
Neurocalcin-delta (NCALD)	OTJZ8UEL	NCALD_HUMAN	Decreases Expression	[59]
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 (GNG11)	OTHIXBGW	GBG11_HUMAN	Increases Expression	[59]
Rho-related GTP-binding protein RhoB (RHOB)	OTHQFQF7	RHOB_HUMAN	Increases Expression	[59]
Small ribosomal subunit protein eS24 (RPS24)	OTSNKIL5	RS24_HUMAN	Increases Expression	[59]
Large ribosomal subunit protein eL31 (RPL31)	OTV9E1OE	RL31_HUMAN	Decreases Expression	[59]
Iroquois-class homeodomain protein IRX-1 (IRX1)	OT0ZN9EJ	IRX1_HUMAN	Increases Expression	[59]
Iroquois-class homeodomain protein IRX-3 (IRX3)	OTLJ48FG	IRX3_HUMAN	Increases Expression	[59]
Fractalkine (CX3CL1)	OTPLGI0E	X3CL1_HUMAN	Increases Expression	[59]
Reelin (RELN)	OTLKMW1O	RELN_HUMAN	Increases Expression	[59]
ETS-related transcription factor Elf-3 (ELF3)	OTUTLEQO	ELF3_HUMAN	Increases Expression	[59]
Protein delta homolog 1 (DLK1)	OTE1VLNB	DLK1_HUMAN	Decreases Expression	[59]
4-aminobutyrate aminotransferase, mitochondrial (ABAT)	OTXAGR7J	GABT_HUMAN	Increases Expression	[59]
Single-stranded DNA-binding protein 2 (SSBP2)	OTYG1G80	SSBP2_HUMAN	Decreases Expression	[59]
Serine beta-lactamase-like protein LACTB, mitochondrial (LACTB)	OTRWGNBF	LACTB_HUMAN	Increases Expression	[59]
Matrix-remodeling-associated protein 7 (MXRA7)	OTVQLYIY	MXRA7_HUMAN	Decreases Expression	[59]
Low-density lipoprotein receptor-related protein 2 (LRP2)	OTZ6W681	LRP2_HUMAN	Decreases Expression	[59]
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform (PPP2R2B)	OTSFVC82	2ABB_HUMAN	Decreases Expression	[59]
Cyclin-dependent kinase 6 (CDK6)	OTR95N0X	CDK6_HUMAN	Increases Expression	[59]
Norrin (NDP)	OTGDJ4US	NDP_HUMAN	Decreases Expression	[59]
Sorbitol dehydrogenase (SORD)	OTC44CR6	DHSO_HUMAN	Decreases Expression	[59]
Sodium channel protein type 7 subunit alpha (SCN7A)	OTK05PXY	SCN7A_HUMAN	Decreases Expression	[59]
Large neutral amino acids transporter small subunit 1 (SLC7A5)	OT2WPVXD	LAT1_HUMAN	Increases Expression	[59]
ATP-dependent 6-phosphofructokinase, platelet type (PFKP)	OTFP7AA8	PFKAP_HUMAN	Increases Expression	[59]
POU domain, class 5, transcription factor 1 (POU5F1)	OTDHHN7O	PO5F1_HUMAN	Increases Expression	[59]
Inactive tyrosine-protein kinase transmembrane receptor ROR1 (ROR1)	OTEUYEW6	ROR1_HUMAN	Increases Expression	[59]
Contactin-2 (CNTN2)	OTQG9W7C	CNTN2_HUMAN	Decreases Expression	[59]
Pro-neuregulin-1, membrane-bound isoform (NRG1)	OTZO6F1X	NRG1_HUMAN	Decreases Expression	[59]
Desmocollin-2 (DSC2)	OTODVH8K	DSC2_HUMAN	Increases Expression	[59]
A-kinase anchor protein 12 (AKAP12)	OTCVRDDX	AKA12_HUMAN	Decreases Expression	[59]
Paired box protein Pax-2 (PAX2)	OTKP1N8F	PAX2_HUMAN	Increases Expression	[59]
Dystonin (DST)	OTHZBM4X	DYST_HUMAN	Decreases Expression	[59]
POU domain, class 3, transcription factor 1 (POU3F1)	OTYARA94	PO3F1_HUMAN	Decreases Expression	[59]
Histone-lysine N-methyltransferase MECOM (MECOM)	OTP983W8	MECOM_HUMAN	Decreases Expression	[59]
Transducin-like enhancer protein 4 (TLE4)	OT4QEH6T	TLE4_HUMAN	Decreases Expression	[59]
Collagen alpha-1(XIV) chain (COL14A1)	OTLNJ13O	COEA1_HUMAN	Increases Expression	[59]
Aldehyde oxidase (AOX1)	OT2FZP6H	AOXA_HUMAN	Decreases Expression	[59]
Myocyte-specific enhancer factor 2C (MEF2C)	OTZGF1Y5	MEF2C_HUMAN	Increases Expression	[59]
Putative POU domain, class 5, transcription factor 1B (POU5F1B)	OT0FKQ51	P5F1B_HUMAN	Increases Expression	[59]
Protein CBFA2T1 (RUNX1T1)	OT30DED5	MTG8_HUMAN	Increases Expression	[59]
Voltage-dependent L-type calcium channel subunit beta-2 (CACNB2)	OT53K8W2	CACB2_HUMAN	Decreases Expression	[59]
3',5'-cyclic-AMP phosphodiesterase 4D (PDE4D)	OT1RWFV0	PDE4D_HUMAN	Increases Expression	[59]
Neuroblast differentiation-associated protein AHNAK (AHNAK)	OT6KH1WG	AHNK_HUMAN	Increases Expression	[59]
Divergent protein kinase domain 1C (DIPK1C)	OT4POSL2	DIK1C_HUMAN	Decreases Expression	[59]
Cingulin-like protein 1 (CGNL1)	OTRE9DGT	CGNL1_HUMAN	Increases Expression	[59]
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 (ST3GAL1)	OTFCO8QX	SIA4A_HUMAN	Increases Expression	[59]
Forkhead box protein O1 (FOXO1)	OTPJRB6D	FOXO1_HUMAN	Increases Expression	[59]
Contactin-1 (CNTN1)	OT7RNPEY	CNTN1_HUMAN	Increases Expression	[59]
Forkhead box protein C1 (FOXC1)	OTOWZGYO	FOXC1_HUMAN	Increases Expression	[59]
Glutamate receptor ionotropic, kainate 3 (GRIK3)	OTX6K345	GRIK3_HUMAN	Decreases Expression	[59]
Rho GTPase-activating protein 5 (ARHGAP5)	OTOQELUN	RHG05_HUMAN	Decreases Expression	[59]
Platelet-activating factor acetylhydrolase (PLA2G7)	OT6H6AMO	PAFA_HUMAN	Increases Expression	[59]
Dual specificity protein phosphatase 4 (DUSP4)	OT6WAO12	DUS4_HUMAN	Decreases Expression	[59]
RE1-silencing transcription factor (REST)	OTLL92LQ	REST_HUMAN	Increases Expression	[59]
BMP and activin membrane-bound inhibitor homolog (BAMBI)	OTCEJ8W5	BAMBI_HUMAN	Increases Expression	[59]
Noggin (NOG)	OTGRHHPG	NOGG_HUMAN	Increases Expression	[59]
N-myc-interactor (NMI)	OTYVG3NM	NMI_HUMAN	Increases Expression	[59]
Zinc transporter ZIP6 (SLC39A6)	OTCYF466	S39A6_HUMAN	Decreases Expression	[59]
Frizzled-5 (FZD5)	OTXFFY56	FZD5_HUMAN	Decreases Expression	[59]
Protein phosphatase 1 regulatory subunit 1A (PPP1R1A)	OTGTAGCV	PPR1A_HUMAN	Increases Expression	[59]
Semaphorin-5A (SEMA5A)	OTUOIOJV	SEM5A_HUMAN	Decreases Expression	[59]
Cullin-3 (CUL3)	OTDNOAPM	CUL3_HUMAN	Decreases Expression	[59]
Cadherin-18 (CDH18)	OTC06P9H	CAD18_HUMAN	Increases Expression	[59]
Ras-related protein Rab-31 (RAB31)	OTMLXQZ0	RAB31_HUMAN	Increases Expression	[59]
CD166 antigen (ALCAM)	OTCO4LP7	CD166_HUMAN	Increases Expression	[59]
Laminin subunit gamma-2 (LAMC2)	OTJMTM72	LAMC2_HUMAN	Increases Expression	[59]
Runt-related transcription factor 3 (RUNX3)	OTITK1XD	RUNX3_HUMAN	Increases Expression	[59]
Integrin alpha-9 (ITGA9)	OTHN1IKA	ITA9_HUMAN	Increases Expression	[59]
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (ENPP2)	OTTUU92F	ENPP2_HUMAN	Increases Expression	[59]
Krueppel-like factor 5 (KLF5)	OT1ABI9N	KLF5_HUMAN	Increases Expression	[59]
Collagen alpha-3(IX) chain (COL9A3)	OTCUJOEK	CO9A3_HUMAN	Increases Expression	[59]
Ras-related protein Rab-33A (RAB33A)	OTHHU6WA	RB33A_HUMAN	Decreases Expression	[59]
Septin-6 (SEPTIN6)	OTIV9RTK	SEPT6_HUMAN	Increases Expression	[59]
Tripartite motif-containing protein 14 (TRIM14)	OTLQKUG0	TRI14_HUMAN	Increases Expression	[59]
Transcription factor E2F2 (E2F2)	OTO75RM7	E2F2_HUMAN	Decreases Expression	[59]
Frizzled-2 (FZD2)	OT952ML1	FZD2_HUMAN	Decreases Expression	[59]
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (PDE3A)	OTKUW1WT	PDE3A_HUMAN	Increases Expression	[59]
Polypeptide N-acetylgalactosaminyltransferase 3 (GALNT3)	OT7M67WT	GALT3_HUMAN	Increases Expression	[59]
Protein disulfide-isomerase A5 (PDIA5)	OT76ZSX5	PDIA5_HUMAN	Increases Expression	[59]
Inositol 1,4,5-trisphosphate receptor type 2 (ITPR2)	OTPHGZ19	ITPR2_HUMAN	Increases Expression	[59]
Caspase-8 (CASP8)	OTA8TVI8	CASP8_HUMAN	Increases Expression	[59]
Metabotropic glutamate receptor 3 (GRM3)	OTJFGE9S	GRM3_HUMAN	Decreases Expression	[59]
AT-rich interactive domain-containing protein 5B (ARID5B)	OTUQ4CQY	ARI5B_HUMAN	Increases Expression	[59]
Nuclear factor of activated T-cells, cytoplasmic 4 (NFATC4)	OTTDCUAO	NFAC4_HUMAN	Decreases Expression	[59]
Opioid-binding protein/cell adhesion molecule (OPCML)	OT93PQ6Y	OPCM_HUMAN	Increases Expression	[59]
Uncharacterized protein KIAA0040 (KIAA0040)	OT27EBY3	K0040_HUMAN	Increases Expression	[59]
Ras GTPase-activating protein 2 (RASA2)	OTL06RG2	RASA2_HUMAN	Decreases Expression	[59]
Ankyrin repeat domain-containing protein 1 (ANKRD1)	OTHJ7JV9	ANKR1_HUMAN	Increases Expression	[59]
Ephrin type-A receptor 7 (EPHA7)	OT3VC211	EPHA7_HUMAN	Increases Expression	[59]
Angiopoietin-1 (ANGPT1)	OTVZ1NG3	ANGP1_HUMAN	Increases Expression	[59]
Ryanodine receptor 3 (RYR3)	OT4EHIP4	RYR3_HUMAN	Decreases Expression	[59]
SH2 domain-containing adapter protein B (SHB)	OTF2HSC0	SHB_HUMAN	Increases Expression	[59]
Homeobox protein SIX1 (SIX1)	OT70YYWM	SIX1_HUMAN	Increases Expression	[59]
ALX homeobox protein 1 (ALX1)	OTZVARA5	ALX1_HUMAN	Increases Expression	[59]
Myosin light chain kinase, smooth muscle (MYLK)	OT78QB4A	MYLK_HUMAN	Decreases Expression	[59]
Metallophosphoesterase MPPED2 (MPPED2)	OT7XLMJ6	MPPD2_HUMAN	Decreases Expression	[59]
Mothers against decapentaplegic homolog 2 (SMAD2)	OTC6VB4K	SMAD2_HUMAN	Decreases Expression	[59]
Nuclear factor erythroid 2-related factor 2 (NFE2L2)	OT0HENJ5	NF2L2_HUMAN	Increases Expression	[59]
Insulin-like growth factor-binding protein 7 (IGFBP7)	OT1D416P	IBP7_HUMAN	Increases Expression	[59]
Laminin subunit alpha-4 (LAMA4)	OTHI7TA0	LAMA4_HUMAN	Increases Expression	[59]
Exostosin-1 (EXT1)	OTRPALJK	EXT1_HUMAN	Decreases Expression	[59]
Cyclin-G2 (CCNG2)	OTII38K2	CCNG2_HUMAN	Decreases Expression	[59]
Prostasin (PRSS8)	OT5KLL35	PRSS8_HUMAN	Increases Expression	[59]
Gamma-interferon-inducible protein 16 (IFI16)	OT4SPU0U	IF16_HUMAN	Increases Expression	[59]
Melanoma-derived growth regulatory protein (MIA)	OTG5FN5S	MIA_HUMAN	Increases Expression	[59]
Cytochrome P450 1B1 (CYP1B1)	OTYXFLSD	CP1B1_HUMAN	Increases Expression	[59]
Dual specificity protein phosphatase 5 (DUSP5)	OTH96RA7	DUS5_HUMAN	Increases Expression	[59]
NADP-dependent malic enzyme, mitochondrial (ME3)	OT3XMLYG	MAON_HUMAN	Decreases Expression	[59]
Reticulon-1 (RTN1)	OTCX1SMK	RTN1_HUMAN	Decreases Expression	[59]
Receptor-type tyrosine-protein phosphatase O (PTPRO)	OTFLKWOY	PTPRO_HUMAN	Decreases Expression	[59]
Tumor protein D53 (TPD52L1)	OTSA6U0I	TPD53_HUMAN	Increases Expression	[59]
Protein inscuteable homolog (INSC)	OTP16ERR	INSC_HUMAN	Increases Expression	[59]
Inverted formin-2 (INF2)	OT8ZM13C	INF2_HUMAN	Increases Expression	[59]
MHC class I polypeptide-related sequence B (MICB)	OTS2DVDW	MICB_HUMAN	Increases Expression	[59]
Centrosomal protein kizuna (KIZ)	OT5VCKSM	KIZ_HUMAN	Decreases Expression	[59]
UPF0561 protein C2orf68 (C2ORF68)	OTNNFK6R	CB068_HUMAN	Decreases Expression	[59]
FH1/FH2 domain-containing protein 3 (FHOD3)	OT1WUBQX	FHOD3_HUMAN	Decreases Expression	[59]
Complement component receptor 1-like protein (CR1L)	OTX3KR7U	CR1L_HUMAN	Increases Expression	[59]
Transcription factor RFX4 (RFX4)	OTYFRHPA	RFX4_HUMAN	Increases Expression	[59]
Cell cycle control protein 50B (TMEM30B)	OTNSBH84	CC50B_HUMAN	Increases Expression	[59]
Transcription factor Sp6 (SP6)	OTRAB1PN	SP6_HUMAN	Increases Expression	[59]
Mitochondrial 10-formyltetrahydrofolate dehydrogenase (ALDH1L2)	OTCH86VF	AL1L2_HUMAN	Increases Expression	[59]
Synaptic vesicle glycoprotein 2C (SV2C)	OTIH108W	SV2C_HUMAN	Increases Expression	[59]
Uncharacterized protein C8orf34 (C8ORF34)	OTXCTHDG	CH034_HUMAN	Increases Expression	[59]
Cell adhesion molecule-related/down-regulated by oncogenes (CDON)	OT81X593	CDON_HUMAN	Increases Expression	[59]
Extracellular tyrosine-protein kinase PKDCC (PKDCC)	OTVXJR26	PKDCC_HUMAN	Increases Expression	[59]
Raftlin-2 (RFTN2)	OT4WYAD9	RFTN2_HUMAN	Increases Expression	[59]
Seizure protein 6 homolog (SEZ6)	OTCD8K5D	SEZ6_HUMAN	Increases Expression	[59]
Acyl-coenzyme A synthetase ACSM3, mitochondrial (ACSM3)	OT0AE1IV	ACSM3_HUMAN	Increases Expression	[59]
Pleckstrin homology-like domain family A member 2 (PHLDA2)	OTMV9DPP	PHLA2_HUMAN	Increases Expression	[59]
Rho GTPase-activating protein 15 (ARHGAP15)	OT9CKHDC	RHG15_HUMAN	Decreases Expression	[59]
Fibulin-7 (FBLN7)	OT1XRDP6	FBLN7_HUMAN	Decreases Expression	[59]
Cordon-bleu protein-like 1 (COBLL1)	OTQFN1TC	COBL1_HUMAN	Increases Expression	[59]
Protein Largen (PRR16)	OTG4TEGR	LARGN_HUMAN	Increases Expression	[59]
TPA-induced transmembrane protein (C3ORF52)	OTI0JAT8	TTMP_HUMAN	Increases Expression	[59]
FRAS1-related extracellular matrix protein 1 (FREM1)	OTMHRV87	FREM1_HUMAN	Increases Expression	[59]
Solute carrier family 25 member 53 (SLC25A53)	OTNHVTOB	S2553_HUMAN	Decreases Expression	[59]
Protein BEX5 (BEX5)	OTZ2RB6L	BEX5_HUMAN	Increases Expression	[59]
Protein phosphatase 1J (PPM1J)	OTM6GDJJ	PPM1J_HUMAN	Increases Expression	[59]
Uncharacterized protein KIAA1755 (KIAA1755)	OT1FCGEW	K1755_HUMAN	Increases Expression	[59]
Collectin-12 (COLEC12)	OTIQTK9G	COL12_HUMAN	Increases Expression	[59]
EGF domain-specific O-linked N-acetylglucosamine transferase (EOGT)	OT4A2A8P	EOGT_HUMAN	Increases Expression	[59]
Neurite extension and migration factor (NEXMIF)	OT576F40	NEXMI_HUMAN	Decreases Expression	[59]
Uncharacterized protein C6orf141 (C6ORF141)	OTUS3SIQ	CF141_HUMAN	Decreases Expression	[59]
Centrosomal protein of 85 kDa-like (CEP85L)	OTSHJFOT	CE85L_HUMAN	Increases Expression	[59]
Transmembrane protein 170B (TMEM170B)	OT4AS8RJ	T170B_HUMAN	Decreases Expression	[59]
Protein FAM162B (FAM162B)	OTZ31RP5	F162B_HUMAN	Increases Expression	[59]
LINE-1 type transposase domain-containing protein 1 (L1TD1)	OTB2W20Y	LITD1_HUMAN	Increases Expression	[59]
KN motif and ankyrin repeat domain-containing protein 4 (KANK4)	OT5WC0Q8	KANK4_HUMAN	Increases Expression	[59]
Transcription factor HES-5 (HES5)	OTW7JEHV	HES5_HUMAN	Decreases Expression	[59]
PX domain-containing protein 1 (PXDC1)	OTQUA3TG	PXDC1_HUMAN	Increases Expression	[59]
Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF3)	OTGQV0CU	BIG3_HUMAN	Decreases Expression	[59]
Glycoprotein endo-alpha-1,2-mannosidase-like protein (MANEAL)	OT248IN0	MANEL_HUMAN	Increases Expression	[59]
G kinase-anchoring protein 1 (GKAP1)	OTHZRJ56	GKAP1_HUMAN	Decreases Expression	[59]
Myomegalin (PDE4DIP)	OTS15WNF	MYOME_HUMAN	Increases Expression	[59]
Uncharacterized protein C1orf53 (C1ORF53)	OTQTOA4D	CA053_HUMAN	Decreases Expression	[59]
Scm-like with four MBT domains protein 2 (SFMBT2)	OTZQT61Q	SMBT2_HUMAN	Increases Expression	[59]
DDB1- and CUL4-associated factor 12-like protein 2 (DCAF12L2)	OTLEF5TY	DC122_HUMAN	Decreases Expression	[59]
Proteasome adapter and scaffold protein ECM29 (ECPAS)	OT1C0KOI	ECM29_HUMAN	Decreases Expression	[59]
B box and SPRY domain-containing protein (BSPRY)	OTVVZRKY	BSPRY_HUMAN	Increases Expression	[59]
Meteorin-like protein (METRNL)	OTB0DDL0	METRL_HUMAN	Increases Expression	[59]
Metalloreductase STEAP3 (STEAP3)	OTS9GZK5	STEA3_HUMAN	Increases Expression	[59]
E3 ubiquitin-protein ligase RNF43 (RNF43)	OT2R9YDP	RNF43_HUMAN	Increases Expression	[59]
LIM/homeobox protein Lhx8 (LHX8)	OT0DFL7C	LHX8_HUMAN	Increases Expression	[59]
Transcription factor Sp5 (SP5)	OT4HUP9B	SP5_HUMAN	Increases Expression	[59]
Tyrosine-protein kinase STYK1 (STYK1)	OT61CSU7	STYK1_HUMAN	Increases Expression	[59]
Volume-regulated anion channel subunit LRRC8E (LRRC8E)	OTUZTANF	LRC8E_HUMAN	Increases Expression	[59]
MFS-type transporter SLC18B1 (SLC18B1)	OT9EVUN1	S18B1_HUMAN	Increases Expression	[59]
TMF-regulated nuclear protein 1 (TRNP1)	OTYYV8LN	TRNP1_HUMAN	Increases Expression	[59]
Epithelial splicing regulatory protein 1 (ESRP1)	OTNCS4SL	ESRP1_HUMAN	Increases Expression	[59]
Cdc42 effector protein 5 (CDC42EP5)	OTQQDUCD	BORG3_HUMAN	Increases Expression	[59]
Protein C3orf33 (C3ORF33)	OTP8MJAN	CC033_HUMAN	Decreases Expression	[59]
DENN domain-containing protein 1B (DENND1B)	OT3VCNPE	DEN1B_HUMAN	Decreases Expression	[59]
Phospholipase B-like 1 (PLBD1)	OTHYEB4W	PLBL1_HUMAN	Increases Expression	[59]
Polypeptide N-acetylgalactosaminyltransferase 18 (GALNT18)	OTKIIELC	GLT18_HUMAN	Increases Expression	[59]
Volume-regulated anion channel subunit LRRC8B (LRRC8B)	OTH2LMJ4	LRC8B_HUMAN	Decreases Expression	[59]
Transmembrane protein 154 (TMEM154)	OTEAFLJE	TM154_HUMAN	Increases Expression	[59]
Transmembrane protein 88 (TMEM88)	OTA96YEL	TMM88_HUMAN	Decreases Expression	[59]
Interleukin-27 receptor subunit alpha (IL27RA)	OTSQBAKI	I27RA_HUMAN	Increases Expression	[59]
Lactase-like protein (LCTL)	OTN36T21	LCTL_HUMAN	Decreases Expression	[59]
Layilin (LAYN)	OT9A9Q1X	LAYN_HUMAN	Increases Expression	[59]
ALK and LTK ligand 2 (ALKAL2)	OTTLHL64	ALKL2_HUMAN	Increases Expression	[59]
Inactive serine protease PAMR1 (PAMR1)	OT83ZH5U	PAMR1_HUMAN	Decreases Expression	[59]
Nephronectin (NPNT)	OTFZAO1G	NPNT_HUMAN	Increases Expression	[59]
Interleukin-20 receptor subunit beta (IL20RB)	OTHFXK95	I20RB_HUMAN	Increases Expression	[59]
R-spondin-2 (RSPO2)	OT3HHXU0	RSPO2_HUMAN	Decreases Expression	[59]
Transmembrane channel-like protein 5 (TMC5)	OTO5D86M	TMC5_HUMAN	Increases Expression	[59]
Transmembrane protein 64 (TMEM64)	OTO9IDFD	TMM64_HUMAN	Increases Expression	[59]
Nesprin-3 (SYNE3)	OTEOJBYB	SYNE3_HUMAN	Increases Expression	[59]
Metastasis-associated in colon cancer protein 1 (MACC1)	OTV3DLX0	MACC1_HUMAN	Increases Expression	[59]
Zinc finger protein basonuclin-2 (BNC2)	OTU22H9Z	BNC2_HUMAN	Increases Expression	[59]
Lysophospholipid acyltransferase 1 (MBOAT1)	OT4XR6TE	MBOA1_HUMAN	Increases Expression	[59]
FYVE, RhoGEF and PH domain-containing protein 5 (FGD5)	OT5VIRP2	FGD5_HUMAN	Increases Expression	[59]
Solute carrier organic anion transporter family member 4C1 (SLCO4C1)	OTVILUUN	SO4C1_HUMAN	Increases Expression	[59]
RNA-binding protein with multiple splicing 2 (RBPMS2)	OTY24L1F	RBPS2_HUMAN	Increases Expression	[59]
Leucine-rich repeat-containing protein 55 (LRRC55)	OT8LQI1W	LRC55_HUMAN	Decreases Expression	[59]
RNA-binding protein 43 (RBM43)	OTANIFBG	RBM43_HUMAN	Increases Expression	[59]
Acyl-CoA dehydrogenase family member 11 (ACAD11)	OT3T9HAX	ACD11_HUMAN	Increases Expression	[59]
BTB/POZ domain-containing protein KCTD1 (KCTD1)	OT89U5MB	KCTD1_HUMAN	Increases Expression	[59]
Mediator of RNA polymerase II transcription subunit 13-like (MED13L)	OTSP1W0F	MD13L_HUMAN	Increases Expression	[59]
Eukaryotic translation initiation factor 3 subunit M (EIF3M)	OTVWEV60	EIF3M_HUMAN	Decreases Expression	[59]
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 (LINGO2)	OT3N88Q1	LIGO2_HUMAN	Increases Expression	[59]
CXXC-type zinc finger protein 5 (CXXC5)	OTGCN3B5	CXXC5_HUMAN	Increases Expression	[59]
Carbohydrate sulfotransferase 15 (CHST15)	OTNTM2SP	CHSTF_HUMAN	Increases Expression	[59]
Monocarboxylate transporter 14 (SLC16A14)	OTUGDEUV	MOT14_HUMAN	Decreases Expression	[59]
C-myc promoter-binding protein (DENND4A)	OT8FFZ29	MYCPP_HUMAN	Increases Expression	[59]
E3 ubiquitin-protein ligase RNF144B (RNF144B)	OTN7FCDE	R144B_HUMAN	Increases Expression	[59]
Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein (BNIPL)	OTDHOA74	BNIPL_HUMAN	Increases Expression	[59]
Cilia- and flagella-associated protein 91 (CFAP91)	OTVDRDGX	CFA91_HUMAN	Decreases Expression	[59]
Transmembrane protein 144 (TMEM144)	OT66EYSR	TM144_HUMAN	Increases Expression	[59]
Uncharacterized protein C11orf96 (C11ORF96)	OTEQU0V7	CK096_HUMAN	Increases Expression	[59]
Amphoterin-induced protein 2 (AMIGO2)	OTPAIT1O	AMGO2_HUMAN	Increases Expression	[59]
Armadillo-like helical domain-containing protein 4 (ARMH4)	OT25GBJM	ARMD4_HUMAN	Decreases Expression	[59]
Sodium/hydrogen exchanger 9B2 (SLC9B2)	OTZVOY8T	SL9B2_HUMAN	Decreases Expression	[59]
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (MAGI2)	OTXDDKZS	MAGI2_HUMAN	Increases Expression	[59]
Regulating synaptic membrane exocytosis protein 1 (RIMS1)	OT10T7CK	RIMS1_HUMAN	Increases Expression	[59]
Inter-alpha-trypsin inhibitor heavy chain H5 (ITIH5)	OTP46PZM	ITIH5_HUMAN	Increases Expression	[59]
Protein FAM124A (FAM124A)	OTF1DJX0	F124A_HUMAN	Decreases Expression	[59]
Glucocorticoid-induced transcript 1 protein (GLCCI1)	OTU0R1CU	GLCI1_HUMAN	Decreases Expression	[59]
Four-jointed box protein 1 (FJX1)	OT8SVTSS	FJX1_HUMAN	Decreases Expression	[59]
Catechol O-methyltransferase domain-containing protein 1 (COMTD1)	OTLQJTBI	CMTD1_HUMAN	Increases Expression	[59]
SEC14 domain and spectrin repeat-containing protein 1 (SESTD1)	OTHH06X8	SESD1_HUMAN	Decreases Expression	[59]
Juxtaposed with another zinc finger protein 1 (JAZF1)	OTXTYSYD	JAZF1_HUMAN	Increases Expression	[59]
Myotubularin-related protein 13 (SBF2)	OTBB8NO8	MTMRD_HUMAN	Increases Expression	[59]
Ras association domain-containing protein 3 (RASSF3)	OT4V9SRK	RASF3_HUMAN	Increases Expression	[59]
E3 ubiquitin-protein ligase TRIM69 (TRIM69)	OTTEGTRD	TRI69_HUMAN	Increases Expression	[59]
Probable D-lactate dehydrogenase, mitochondrial (LDHD)	OTTKLJWP	LDHD_HUMAN	Increases Expression	[59]
Chondroitin sulfate synthase 1 (CHSY1)	OTB1XSSF	CHSS1_HUMAN	Increases Expression	[59]
Dynein regulatory complex protein 11 (IQCA1)	OTFBF3FI	DRC11_HUMAN	Increases Expression	[59]
Protein phosphatase 1 regulatory subunit 3B (PPP1R3B)	OTVCRXEZ	PPR3B_HUMAN	Increases Expression	[59]
Collagen alpha-1(XXIII) chain (COL23A1)	OTYE0N3I	CONA1_HUMAN	Increases Expression	[59]
Testis development-related protein (TDRP)	OTEFLMGF	TDRP_HUMAN	Increases Expression	[59]
Podoplanin (PDPN)	OTBUV19I	PDPN_HUMAN	Increases Expression	[59]
Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPARGC1B)	OTN6FKCB	PRGC2_HUMAN	Increases Expression	[59]
Rab11 family-interacting protein 4 (RAB11FIP4)	OTIGHER7	RFIP4_HUMAN	Increases Expression	[59]
Inactive tyrosine-protein kinase PRAG1 (PRAG1)	OTV83SGI	PRAG1_HUMAN	Increases Expression	[59]
Purine nucleoside phosphorylase LACC1 (LACC1)	OT4SBHI8	LACC1_HUMAN	Increases Expression	[59]
LysM and putative peptidoglycan-binding domain-containing protein 2 (LYSMD2)	OT1VCC2M	LYSM2_HUMAN	Increases Expression	[59]
Proline-rich protein 15 (PRR15)	OTJHSY8G	PRR15_HUMAN	Increases Expression	[59]
Neuron navigator 3 (NAV3)	OT97M1TR	NAV3_HUMAN	Increases Expression	[59]
Immunoglobulin superfamily DCC subclass member 3 (IGDCC3)	OTGR1KA4	IGDC3_HUMAN	Increases Expression	[59]
Sodium channel subunit beta-4 (SCN4B)	OT3JSUWO	SCN4B_HUMAN	Increases Expression	[59]
Sphingosine-1-phosphate phosphatase 2 (SGPP2)	OTIDIJCR	SGPP2_HUMAN	Increases Expression	[59]
Uncharacterized protein C12orf56 (C12ORF56)	OT4KDTKF	CL056_HUMAN	Increases Expression	[59]
Solute carrier family 35 member F2 (SLC35F2)	OTSAD4EQ	S35F2_HUMAN	Increases Expression	[59]
Transcription factor Sp8 (SP8)	OTLCMPKH	SP8_HUMAN	Decreases Expression	[59]
Procollagen galactosyltransferase 2 (COLGALT2)	OTV9EDZB	GT252_HUMAN	Decreases Expression	[59]
Ras and EF-hand domain-containing protein (RASEF)	OTGSAM2E	RASEF_HUMAN	Increases Expression	[59]
Myocardin (MYOCD)	OTSJNHTH	MYCD_HUMAN	Increases Expression	[59]
Protein SIX6OS1 (C14ORF39)	OTFKQ6HO	S6OS1_HUMAN	Decreases Expression	[59]
Neuroligin-1 (NLGN1)	OTGHRRFQ	NLGN1_HUMAN	Decreases Expression	[59]
Protein FAM43A (FAM43A)	OT5RPQRE	FA43A_HUMAN	Increases Expression	[59]
Glycerol-3-phosphate dehydrogenase 1-like protein (GPD1L)	OTVLWW9T	GPD1L_HUMAN	Increases Expression	[59]
ELMO domain-containing protein 1 (ELMOD1)	OT0WRVJC	ELMD1_HUMAN	Increases Expression	[59]
Mucin-15 (MUC15)	OT3PQT6L	MUC15_HUMAN	Increases Expression	[59]
Rho GTPase-activating protein 18 (ARHGAP18)	OTYMJP6H	RHG18_HUMAN	Increases Expression	[59]
MICAL-like protein 1 (MICALL1)	OTHG9B2U	MILK1_HUMAN	Increases Expression	[59]
Protein phosphatase Mn(2+)-dependent 1K (PPM1K)	OTNZ4N4E	PPM1K_HUMAN	Increases Expression	[59]
Thioredoxin domain-containing protein 3 (NME8)	OT4RULP5	TXND3_HUMAN	Increases Expression	[59]
Inactive carboxypeptidase-like protein X2 (CPXM2)	OTDJNOTR	CPXM2_HUMAN	Increases Expression	[59]
Secreted frizzled-related protein 1 (SFRP1)	OT0U9G41	SFRP1_HUMAN	Decreases Expression	[59]
Protein limb expression 1 homolog (LIX1)	OT1CPNCC	LIX1_HUMAN	Decreases Expression	[59]
RING finger protein 175 (RNF175)	OTKAZ8ZW	RN175_HUMAN	Decreases Expression	[59]
Reprimo-like protein (RPRML)	OTPOESFN	RPRML_HUMAN	Increases Expression	[59]
Serine/threonine-protein kinase DCLK2 (DCLK2)	OTT0AU1C	DCLK2_HUMAN	Decreases Expression	[59]
Ephexin-1 (NGEF)	OT9QUXJ3	NGEF_HUMAN	Increases Expression	[59]
Eukaryotic translation initiation factor 4E type 3 (EIF4E3)	OTTWVS2R	IF4E3_HUMAN	Decreases Expression	[59]
E3 ubiquitin-protein ligase RNF182 (RNF182)	OT08FLHZ	RN182_HUMAN	Decreases Expression	[59]
CUGBP Elav-like family member 5 (CELF5)	OT02OG9N	CELF5_HUMAN	Decreases Expression	[59]
Protocadherin-20 (PCDH20)	OTFSNRXK	PCD20_HUMAN	Increases Expression	[59]
Leucine-rich repeat-containing protein 17 (LRRC17)	OT3NZSX3	LRC17_HUMAN	Increases Expression	[59]
APC membrane recruitment protein 2 (AMER2)	OTA1Q07C	AMER2_HUMAN	Increases Expression	[59]
BMP-binding endothelial regulator protein (BMPER)	OTBYON4H	BMPER_HUMAN	Increases Expression	[59]
V-type proton ATPase subunit d 2 (ATP6V0D2)	OTMOZJO0	VA0D2_HUMAN	Increases Expression	[59]
Tetratricopeptide repeat protein 29 (TTC29)	OT37KCUL	TTC29_HUMAN	Increases Expression	[59]
Fibronectin type III domain-containing protein 5 (FNDC5)	OT5CSK9X	FNDC5_HUMAN	Decreases Expression	[59]
Transmembrane protein 178A (TMEM178A)	OTQZY4NP	T178A_HUMAN	Decreases Expression	[59]
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH)	OTBIN5IP	SCPDL_HUMAN	Decreases Expression	[59]
Carbohydrate sulfotransferase 4 (CHST4)	OTESMIW5	CHST4_HUMAN	Increases Expression	[59]
Potassium voltage-gated channel subfamily H member 5 (KCNH5)	OTVAHEAQ	KCNH5_HUMAN	Decreases Expression	[59]
Protein FAM13C (FAM13C)	OTVAGUOV	FA13C_HUMAN	Increases Expression	[59]
Zinc finger protein GLIS3 (GLIS3)	OTBC960E	GLIS3_HUMAN	Decreases Expression	[59]
Neuron navigator 1 (NAV1)	OT667KTL	NAV1_HUMAN	Decreases Expression	[59]
Nesprin-1 (SYNE1)	OTSBSLUH	SYNE1_HUMAN	Increases Expression	[59]
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 (B3GNT7)	OT8UTTXF	B3GN7_HUMAN	Increases Expression	[59]
Interleukin-17 receptor D (IL17RD)	OTKD9XST	I17RD_HUMAN	Decreases Expression	[59]
Bestrophin-4 (BEST4)	OT6S406I	BEST4_HUMAN	Decreases Expression	[59]
Semaphorin-6D (SEMA6D)	OTU0UAZS	SEM6D_HUMAN	Decreases Expression	[59]
Cell adhesion molecule 4 (CADM4)	OT0TFMFE	CADM4_HUMAN	Decreases Expression	[59]
Nuclear receptor coactivator 7 (NCOA7)	OT2CNBOG	NCOA7_HUMAN	Decreases Expression	[59]
LIM domain only protein 3 (LMO3)	OTR7AJHN	LMO3_HUMAN	Decreases Expression	[59]
Fibroblast growth factor-binding protein 3 (FGFBP3)	OTWM1KCM	FGFP3_HUMAN	Increases Expression	[59]
DEP domain-containing mTOR-interacting protein (DEPTOR)	OTCBP1BT	DPTOR_HUMAN	Increases Expression	[59]
3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic (HMGCLL1)	OT9SQ5PU	HMGC2_HUMAN	Decreases Expression	[59]
E3 ubiquitin-protein ligase LNX (LNX1)	OTZWFMAZ	LNX1_HUMAN	Increases Expression	[59]
Synaptoporin (SYNPR)	OTNCJ9L0	SYNPR_HUMAN	Increases Expression	[59]
Fez family zinc finger protein 2 (FEZF2)	OTU4TXIW	FEZF2_HUMAN	Decreases Expression	[59]
Transmembrane protein 163 (TMEM163)	OTCT1Y1L	TM163_HUMAN	Decreases Expression	[59]
E3 ubiquitin-protein ligase RNF217 (RNF217)	OTAX91ES	RN217_HUMAN	Increases Expression	[59]
Fibronectin type 3 and ankyrin repeat domains protein 1 (FANK1)	OT5641YJ	FANK1_HUMAN	Decreases Expression	[59]
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (PREX1)	OTUTPVA9	PREX1_HUMAN	Increases Expression	[59]
Mucolipin-3 (MCOLN3)	OTCRPRVS	MCLN3_HUMAN	Increases Expression	[59]
Protocadherin Fat 3 (FAT3)	OT3C6H8W	FAT3_HUMAN	Decreases Expression	[59]
A disintegrin and metalloproteinase with thrombospondin motifs 15 (ADAMTS15)	OTYB6JS3	ATS15_HUMAN	Increases Expression	[59]
A disintegrin and metalloproteinase with thrombospondin motifs 19 (ADAMTS19)	OTEG5Q2G	ATS19_HUMAN	Increases Expression	[59]
Grainyhead-like protein 3 homolog (GRHL3)	OT1V4ZEH	GRHL3_HUMAN	Increases Expression	[59]
Actin filament-associated protein 1-like 1 (AFAP1L1)	OTWNTNDB	AF1L1_HUMAN	Increases Expression	[59]
DENN domain-containing protein 1A (DENND1A)	OTONDAA0	DEN1A_HUMAN	Decreases Expression	[59]
Serine/threonine-protein kinase 32A (STK32A)	OTONYLYO	ST32A_HUMAN	Decreases Expression	[59]
RelA-associated inhibitor (PPP1R13L)	OTNCPLWE	IASPP_HUMAN	Increases Expression	[59]
Protein prune homolog 2 (PRUNE2)	OTGW2974	PRUN2_HUMAN	Decreases Expression	[59]
DEP domain-containing protein 1B (DEPDC1B)	OTMVFOT1	DEP1B_HUMAN	Decreases Expression	[59]
DDB1- and CUL4-associated factor 4 (DCAF4)	OTQU0EUO	DCAF4_HUMAN	Increases Expression	[59]
Pleckstrin homology-like domain family A member 1 (PHLDA1)	OTFTWMIQ	PHLA1_HUMAN	Increases Expression	[59]
PH-interacting protein (PHIP)	OTZY806Z	PHIP_HUMAN	Decreases Expression	[59]
Cholesterol transporter ABCA5 (ABCA5)	OT4B9D92	ABCA5_HUMAN	Decreases Expression	[59]
Secretogranin-3 (SCG3)	OTUYSV2S	SCG3_HUMAN	Increases Expression	[59]
Adhesion G-protein coupled receptor V1 (ADGRV1)	OTLVXHHP	AGRV1_HUMAN	Decreases Expression	[59]
Connector enhancer of kinase suppressor of ras 2 (CNKSR2)	OTAGERJ2	CNKR2_HUMAN	Decreases Expression	[59]
BRI3-binding protein (BRI3BP)	OTWCFPRM	BRI3B_HUMAN	Increases Expression	[59]
Nanos homolog 1 (NANOS1)	OT3UNZZY	NANO1_HUMAN	Decreases Expression	[59]
E3 ubiquitin-protein ligase MYLIP (MYLIP)	OTL0PFGV	MYLIP_HUMAN	Increases Expression	[59]
Jun dimerization protein 2 (JDP2)	OTW35WKX	JDP2_HUMAN	Increases Expression	[59]
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 (ARAP2)	OTBXYFRH	ARAP2_HUMAN	Increases Expression	[59]
Transcription factor AP-2-beta (TFAP2B)	OTR1T8E9	AP2B_HUMAN	Increases Expression	[59]
Protein FAM168A (FAM168A)	OTDXQCS5	F168A_HUMAN	Decreases Expression	[59]
Transcription factor AP-2 gamma (TFAP2C)	OTUDIW05	AP2C_HUMAN	Increases Expression	[59]
Secreted frizzled-related protein 3 (FRZB)	OTTO3DPY	SFRP3_HUMAN	Decreases Expression	[59]
Ras-responsive element-binding protein 1 (RREB1)	OT62460U	RREB1_HUMAN	Increases Expression	[59]
Hyaluronan synthase 2 (HAS2)	OTTD3PAL	HYAS2_HUMAN	Increases Expression	[59]
Coronin-2A (CORO2A)	OTVK7PK3	COR2A_HUMAN	Increases Expression	[59]
Histone acetyltransferase KAT2B (KAT2B)	OTWQITWK	KAT2B_HUMAN	Decreases Expression	[59]
Protein kinase C-binding protein NELL1 (NELL1)	OTF3TX3N	NELL1_HUMAN	Increases Expression	[59]
Kinesin-associated protein 3 (KIFAP3)	OT450PAO	KIFA3_HUMAN	Increases Expression	[59]
BLOC-3 complex member HPS1 (HPS1)	OTKS5I7T	HPS1_HUMAN	Increases Expression	[59]
Deleted in azoospermia-like (DAZL)	OTZMTD4R	DAZL_HUMAN	Decreases Expression	[59]
Receptor-type tyrosine-protein phosphatase N2 (PTPRN2)	OTL6SH28	PTPR2_HUMAN	Decreases Expression	[59]
Stathmin-2 (STMN2)	OT0FUHLH	STMN2_HUMAN	Increases Expression	[59]
Protein naked cuticle homolog 1 (NKD1)	OTY3MO97	NKD1_HUMAN	Increases Expression	[59]
Protein TMEPAI (PMEPA1)	OTY8Z9UF	PMEPA_HUMAN	Increases Expression	[59]
Mitochondrial amidoxime reducing component 2 (MTARC2)	OT8B6LVD	MARC2_HUMAN	Increases Expression	[59]
Terminal nucleotidyltransferase 5B (TENT5B)	OTO2P28B	TET5B_HUMAN	Increases Expression	[59]
Copine-4 (CPNE4)	OTTAGM5L	CPNE4_HUMAN	Increases Expression	[59]
SPRY domain-containing SOCS box protein 4 (SPSB4)	OTG9MLO4	SPSB4_HUMAN	Increases Expression	[59]
SOSS complex subunit B2 (NABP1)	OTFTNFHW	SOSB2_HUMAN	Increases Expression	[59]
Ras-related protein Rab-7b (RAB7B)	OT60A0E9	RAB7B_HUMAN	Increases Expression	[59]
Transmembrane protein 125 (TMEM125)	OTWF8MC1	TM125_HUMAN	Increases Expression	[59]
Claudin-23 (CLDN23)	OTN5RV40	CLD23_HUMAN	Increases Expression	[59]
Transmembrane protein 18 (TMEM18)	OT05YQ1E	TMM18_HUMAN	Decreases Expression	[59]
Repulsive guidance molecule A (RGMA)	OTZAMDO2	RGMA_HUMAN	Decreases Expression	[59]
SH3 domain-containing kinase-binding protein 1 (SH3KBP1)	OTIUA60B	SH3K1_HUMAN	Increases Expression	[59]
Serine/threonine-protein kinase Sgk3 (SGK3)	OTQ6QO99	SGK3_HUMAN	Increases Expression	[59]
BTB/POZ domain-containing protein KCTD12 (KCTD12)	OTPYKT4Z	KCD12_HUMAN	Increases Expression	[59]
Endoplasmic reticulum resident protein 27 (ERP27)	OTVMGE2H	ERP27_HUMAN	Increases Expression	[59]
Polyadenylate-binding protein 5 (PABPC5)	OTLUTQ02	PABP5_HUMAN	Increases Expression	[59]
Ras-related protein Rab-3C (RAB3C)	OTFTJNGA	RAB3C_HUMAN	Increases Expression	[59]
Elongator complex protein 4 (ELP4)	OTP5GZ9V	ELP4_HUMAN	Decreases Expression	[59]
Multivesicular body subunit 12A (MVB12A)	OT3737K0	MB12A_HUMAN	Decreases Expression	[59]
CB1 cannabinoid receptor-interacting protein 1 (CNRIP1)	OTXPWJ56	CNRP1_HUMAN	Increases Expression	[59]
Protein FAM89A (FAM89A)	OTNASAXT	FA89A_HUMAN	Increases Expression	[59]
Secreted frizzled-related protein 2 (SFRP2)	OT8GZ0CA	SFRP2_HUMAN	Decreases Expression	[59]
Transmembrane protein 169 (TMEM169)	OTKXDYVC	TM169_HUMAN	Decreases Expression	[59]
4-hydroxyphenylpyruvate dioxygenase-like protein (HPDL)	OTW7D1SV	HPDL_HUMAN	Increases Expression	[59]
Epithelial-stromal interaction protein 1 (EPSTI1)	OT75I1UH	ESIP1_HUMAN	Increases Expression	[59]
Leucine-rich repeats and immunoglobulin-like domains protein 1 (LRIG1)	OTY5HZN5	LRIG1_HUMAN	Decreases Expression	[59]
Microtubule-associated protein 6 (MAP6)	OTPUI00F	MAP6_HUMAN	Decreases Expression	[59]
Coiled-coil domain-containing protein 136 (CCDC136)	OTPOV391	CC136_HUMAN	Decreases Expression	[59]
Golgi-associated RAB2 interactor protein 1B (GARIN1B)	OTWPN527	GAR1B_HUMAN	Decreases Expression	[59]
Phospholipase A and acyltransferase 5 (PLAAT5)	OT9JFFO2	PLAT5_HUMAN	Increases Expression	[59]
Sushi domain-containing protein 3 (SUSD3)	OTERJTUL	SUSD3_HUMAN	Increases Expression	[59]
Guanine nucleotide exchange factor C9orf72 (C9ORF72)	OT0WH38E	CI072_HUMAN	Decreases Expression	[59]
Kremen protein 1 (KREMEN1)	OTGJFSAC	KREM1_HUMAN	Increases Expression	[59]
Transmembrane protein 74 (TMEM74)	OT3IZBM0	TMM74_HUMAN	Decreases Expression	[59]
TOX high mobility group box family member 2 (TOX2)	OT7RZRVK	TOX2_HUMAN	Decreases Expression	[59]
Patched domain-containing protein 1 (PTCHD1)	OTFDLU5S	PTHD1_HUMAN	Increases Expression	[59]
Dachshund homolog 2 (DACH2)	OT33KEUZ	DACH2_HUMAN	Increases Expression	[59]
Chloride intracellular channel protein 6 (CLIC6)	OTFMSU5U	CLIC6_HUMAN	Increases Expression	[59]
Noelin-3 (OLFM3)	OTBHPDTL	NOE3_HUMAN	Increases Expression	[59]
Leucine-rich repeat-containing protein 3B (LRRC3B)	OT9VDGPR	LRC3B_HUMAN	Decreases Expression	[59]
Secretoglobin family 3A member 2 (SCGB3A2)	OTB63PHR	SG3A2_HUMAN	Increases Expression	[59]
VPS10 domain-containing receptor SorCS2 (SORCS2)	OTBF3DYK	SORC2_HUMAN	Decreases Expression	[59]
Rho GTPase-activating protein 7 (DLC1)	OTP8LMCR	RHG07_HUMAN	Increases Expression	[59]
DEP domain-containing protein 7 (DEPDC7)	OT62C942	DEPD7_HUMAN	Increases Expression	[59]
Rab-3A-interacting protein (RAB3IP)	OT3UPQAA	RAB3I_HUMAN	Decreases Expression	[59]
Homeobox protein ARX (ARX)	OTBGYH25	ARX_HUMAN	Decreases Expression	[59]
Lipase maturation factor 1 (LMF1)	OTOL14ZD	LMF1_HUMAN	Increases Expression	[59]
Doublesex- and mab-3-related transcription factor A2 (DMRTA2)	OTWQR1M7	DMTA2_HUMAN	Increases Expression	[59]
Mucin-4 (MUC4)	OTLT11V1	MUC4_HUMAN	Increases Expression	[59]
Glutamate decarboxylase 1 (GAD1)	OT52Z39J	DCE1_HUMAN	Increases Expression	[59]
Protein kinase C-binding protein NELL2 (NELL2)	OTS4MJZ7	NELL2_HUMAN	Decreases Expression	[59]
Sphingosine 1-phosphate receptor 3 (S1PR3)	OTXBIYO8	S1PR3_HUMAN	Decreases Expression	[59]
Krueppel-like factor 6 (KLF6)	OTQY9S7F	KLF6_HUMAN	Increases Expression	[59]
Fasciculation and elongation protein zeta-1 (FEZ1)	OTWCXPRE	FEZ1_HUMAN	Decreases Expression	[59]
Pituitary homeobox 2 (PITX2)	OTWMXAOY	PITX2_HUMAN	Increases Expression	[59]
Endothelial PAS domain-containing protein 1 (EPAS1)	OTRE3O8U	EPAS1_HUMAN	Increases Expression	[59]
Epidermal growth factor-like protein 8 (EGFL8)	OTECTJ7K	EGFL8_HUMAN	Increases Expression	[59]
Forkhead box protein C2 (FOXC2)	OT83P1E0	FOXC2_HUMAN	Increases Expression	[59]
Cbp/p300-interacting transactivator 2 (CITED2)	OT812TV7	CITE2_HUMAN	Increases Expression	[59]
Retinoic acid receptor responder protein 2 (RARRES2)	OT1BJE8K	RARR2_HUMAN	Increases Expression	[59]
Semaphorin-3C (SEMA3C)	OTEGUY7F	SEM3C_HUMAN	Increases Expression	[59]
Fermitin family homolog 1 (FERMT1)	OT626PBA	FERM1_HUMAN	Increases Expression	[59]
Synaptotagmin-11 (SYT11)	OTLRTZEI	SYT11_HUMAN	Decreases Expression	[59]
Brain-enriched guanylate kinase-associated protein (BEGAIN)	OTT3UD2K	BEGIN_HUMAN	Decreases Expression	[59]
Protein ABHD14A (ABHD14A)	OT94GKE1	ABHEA_HUMAN	Decreases Expression	[59]
Ribonuclease P protein subunit p25 (RPP25)	OTEN6QN7	RPP25_HUMAN	Increases Expression	[59]
Glutathione-specific gamma-glutamylcyclotransferase 1 (CHAC1)	OTJGE772	CHAC1_HUMAN	Increases Expression	[59]
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 (ST6GALNAC5)	OTH91ETM	SIA7E_HUMAN	Decreases Expression	[59]
Cell cycle regulator of non-homologous end joining (CYREN)	OT5ZL00R	CYREN_HUMAN	Decreases Expression	[59]
Brother of CDO (BOC)	OTXBCY9W	BOC_HUMAN	Increases Expression	[59]
RNA-binding protein 24 (RBM24)	OTQI1AR1	RBM24_HUMAN	Decreases Expression	[59]
Receptor for retinol uptake STRA6 (STRA6)	OT2IDF27	STRA6_HUMAN	Increases Expression	[59]
Sphingosine-1-phosphate phosphatase 1 (SGPP1)	OT9X54CQ	SGPP1_HUMAN	Increases Expression	[59]
Sal-like protein 3 (SALL3)	OTJ2LZKQ	SALL3_HUMAN	Decreases Expression	[59]
Oxysterol-binding protein-related protein 10 (OSBPL10)	OT0TFMBE	OSB10_HUMAN	Increases Expression	[59]
Complement C1q tumor necrosis factor-related protein 4 (C1QTNF4)	OTHD4Y9D	C1QT4_HUMAN	Decreases Expression	[59]
Microtubule-associated proteins 1A/1B light chain 3C (MAP1LC3C)	OTM4ECDK	MLP3C_HUMAN	Increases Expression	[59]
R-spondin-3 (RSPO3)	OTZK8GDS	RSPO3_HUMAN	Increases Expression	[59]
Histone deacetylase 8 (HDAC8)	OT5L4RYX	HDAC8_HUMAN	Increases Expression	[59]
Dedicator of cytokinesis protein 9 (DOCK9)	OT84H8AD	DOCK9_HUMAN	Increases Expression	[59]
Iroquois-class homeodomain protein IRX-2 (IRX2)	OTBHXXQ2	IRX2_HUMAN	Increases Expression	[59]
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 (NMNAT2)	OT5JLP2H	NMNA2_HUMAN	Increases Expression	[59]
Thiamine transporter 2 (SLC19A3)	OTOWP1CT	S19A3_HUMAN	Increases Expression	[59]
E3 ubiquitin-protein ligase TRIM9 (TRIM9)	OTKYG33W	TRIM9_HUMAN	Increases Expression	[59]
Tripartite motif-containing protein 6 (TRIM6)	OTBSMX0B	TRIM6_HUMAN	Increases Expression	[59]
Protein TANC1 (TANC1)	OTF6TZ8E	TANC1_HUMAN	Increases Expression	[59]
Ethanolaminephosphotransferase 1 (SELENOI)	OTX2A47A	EPT1_HUMAN	Increases Expression	[59]
SRC kinase signaling inhibitor 1 (SRCIN1)	OTQZNQQ5	SRCN1_HUMAN	Decreases Expression	[59]
Metal cation symporter ZIP8 (SLC39A8)	OT6C6MNV	S39A8_HUMAN	Increases Expression	[59]
Immortalization up-regulated protein (C19ORF33)	OTOYH74A	IMUP_HUMAN	Increases Expression	[59]
PR domain zinc finger protein 14 (PRDM14)	OTWZKY4L	PRD14_HUMAN	Increases Expression	[59]
NUAK family SNF1-like kinase 2 (NUAK2)	OTUEZLO8	NUAK2_HUMAN	Decreases Expression	[59]
CYFIP-related Rac1 interactor A (CYRIA)	OT2VJ767	CYRIA_HUMAN	Increases Expression	[59]
Ras-related protein Rab-17 (RAB17)	OT7NBUGQ	RAB17_HUMAN	Increases Expression	[59]
B-cell lymphoma/leukemia 11A (BCL11A)	OTI6ZBP6	BC11A_HUMAN	Increases Expression	[59]
Kinesin-like protein KIF13A (KIF13A)	OTSSZGBQ	KI13A_HUMAN	Decreases Expression	[59]
Sphingosine 1-phosphate receptor 5 (S1PR5)	OTQF1R0U	S1PR5_HUMAN	Increases Expression	[59]
Synaptotagmin-4 (SYT4)	OTA1D7VL	SYT4_HUMAN	Increases Expression	[59]
Cysteine-rich secretory protein LCCL domain-containing 1 (CRISPLD1)	OT38HXJP	CRLD1_HUMAN	Increases Expression	[59]
Sorting nexin-25 (SNX25)	OT8JY8M1	SNX25_HUMAN	Decreases Expression	[59]
Leucine-rich repeat neuronal protein 3 (LRRN3)	OT7X0AA7	LRRN3_HUMAN	Increases Expression	[59]
Calsyntenin-2 (CLSTN2)	OT2PJYHX	CSTN2_HUMAN	Increases Expression	[59]
SPARC-related modular calcium-binding protein 1 (SMOC1)	OTJG2JQY	SMOC1_HUMAN	Decreases Expression	[59]
DNA transposase THAP9 (THAP9)	OTY4TSJO	THAP9_HUMAN	Decreases Expression	[59]
SLIT and NTRK-like protein 6 (SLITRK6)	OTLNWI5G	SLIK6_HUMAN	Increases Expression	[59]
Epithelial splicing regulatory protein 2 (ESRP2)	OTVTKJ4I	ESRP2_HUMAN	Increases Expression	[59]
Dedicator of cytokinesis protein 5 (DOCK5)	OT63I0CL	DOCK5_HUMAN	Increases Expression	[59]
NIPA-like protein 2 (NIPAL2)	OTX9UREP	NPAL2_HUMAN	Increases Expression	[59]
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial (MTHFD2L)	OTDYNXRG	MTD2L_HUMAN	Increases Expression	[59]
Nuclear body protein SP140-like protein (SP140L)	OTL30JKT	SP14L_HUMAN	Increases Expression	[59]
Chondrolectin (CHODL)	OTVCNOUQ	CHODL_HUMAN	Increases Expression	[59]
Homeobox protein NANOG (NANOG)	OTUEY1FM	NANOG_HUMAN	Increases Expression	[59]
Adhesion G protein-coupled receptor L3 (ADGRL3)	OT81Q8LY	AGRL3_HUMAN	Decreases Expression	[59]
Netrin-4 (NTN4)	OTDRRMP3	NET4_HUMAN	Decreases Expression	[59]
V-type proton ATPase 116 kDa subunit a 4 (ATP6V0A4)	OT149Z7Q	VPP4_HUMAN	Increases Expression	[59]
Collectrin (CLTRN)	OTXGFJ3F	CLTRN_HUMAN	Decreases Expression	[59]
Ethanolamine kinase 1 (ETNK1)	OTDKB4DQ	EKI1_HUMAN	Increases Expression	[59]
Popeye domain-containing protein 3 (POPDC3)	OTN4FJ5J	POPD3_HUMAN	Decreases Expression	[59]
Aryl hydrocarbon receptor nuclear translocator 2 (ARNT2)	OTAQD3YV	ARNT2_HUMAN	Decreases Expression	[59]
Prokineticin-2 (PROK2)	OT70IFEZ	PROK2_HUMAN	Decreases Expression	[59]
Sodium/potassium/calcium exchanger 3 (SLC24A3)	OTEJN38N	NCKX3_HUMAN	Increases Expression	[59]
Mineralization regulator ANKH (ANKH)	OTCN25R5	ANKH_HUMAN	Increases Expression	[59]
UPF0606 protein KIAA1549 (KIAA1549)	OTA5B18F	K1549_HUMAN	Decreases Expression	[59]
Band 4.1-like protein 5 (EPB41L5)	OTPPQPLU	E41L5_HUMAN	Increases Expression	[59]
Solute carrier family 40 member 1 (SLC40A1)	OT8RV2VY	S40A1_HUMAN	Increases Expression	[59]
Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A)	OT5V52LN	TNR12_HUMAN	Increases Expression	[59]
Mid1-interacting protein 1 (MID1IP1)	OTFCORJM	M1IP1_HUMAN	Increases Expression	[59]
Frizzled-3 (FZD3)	OTIWDN78	FZD3_HUMAN	Decreases Expression	[59]
Nuclear receptor-interacting protein 3 (NRIP3)	OTU15GMK	NRIP3_HUMAN	Decreases Expression	[59]
Signal peptide, CUB and EGF-like domain-containing protein 2 (SCUBE2)	OT661S7D	SCUB2_HUMAN	Decreases Expression	[59]
Solute carrier family 52, riboflavin transporter, member 3 (SLC52A3)	OT1FHFMK	S52A3_HUMAN	Increases Expression	[59]
E3 ubiquitin-protein ligase Jade-2 (JADE2)	OTVG2MYF	JADE2_HUMAN	Increases Expression	[59]
Ras-related GTP-binding protein D (RRAGD)	OTXLVWAH	RRAGD_HUMAN	Decreases Expression	[59]
Coiled-coil domain-containing protein 177 (CCDC177)	OT44WWP5	CC177_HUMAN	Decreases Expression	[59]
Sialic acid synthase (NANS)	OTMQ2FUH	SIAS_HUMAN	Increases Expression	[59]
Platelet-derived growth factor C (PDGFC)	OT3ZJ0XU	PDGFC_HUMAN	Increases Expression	[59]
N-lysine methyltransferase SMYD2 (SMYD2)	OTN8035R	SMYD2_HUMAN	Increases Expression	[59]
Bromodomain adjacent to zinc finger domain protein 1A (BAZ1A)	OTWHOVZS	BAZ1A_HUMAN	Increases Expression	[59]
Olfactomedin-like protein 3 (OLFML3)	OTDN45FN	OLFL3_HUMAN	Increases Expression	[59]
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 (C1GALT1)	OT2ZSZ6P	C1GLT_HUMAN	Increases Expression	[59]
Glutaredoxin-2, mitochondrial (GLRX2)	OT4LIRBC	GLRX2_HUMAN	Increases Expression	[59]
Protein reprimo (RPRM)	OTNNBAS1	RPRM_HUMAN	Increases Expression	[59]
Probable G-protein coupled receptor 173 (GPR173)	OT8F8XR1	GP173_HUMAN	Decreases Expression	[59]
Probable G-protein coupled receptor 27 (GPR27)	OTH4KQPI	GPR27_HUMAN	Decreases Expression	[59]
Asc-type amino acid transporter 1 (SLC7A10)	OTN1S03Q	AAA1_HUMAN	Increases Expression	[59]
EMILIN-3 (EMILIN3)	OT2BZTSU	EMIL3_HUMAN	Decreases Expression	[59]
Teneurin-2 (TENM2)	OTPLUYEF	TEN2_HUMAN	Increases Expression	[59]
Obg-like ATPase 1 (OLA1)	OTAPOTTG	OLA1_HUMAN	Decreases Expression	[59]
Muscleblind-like protein 3 (MBNL3)	OT2T2YOK	MBNL3_HUMAN	Increases Expression	[59]
RNA binding protein fox-1 homolog 1 (RBFOX1)	OTFPKEL7	RFOX1_HUMAN	Increases Expression	[59]
Calcium uniporter regulatory subunit MCUb, mitochondrial (MCUB)	OTXLLSIZ	MCUB_HUMAN	Decreases Expression	[59]
Ras-related protein Rab-20 (RAB20)	OTP9OOVS	RAB20_HUMAN	Increases Expression	[59]
Very long chain fatty acid elongase 2 (ELOVL2)	OTDAF6U3	ELOV2_HUMAN	Decreases Expression	[59]
Sphingosine kinase 1 (SPHK1)	OTWYPBVD	SPHK1_HUMAN	Increases Expression	[59]
Dapper homolog 1 (DACT1)	OT19Z704	DACT1_HUMAN	Increases Expression	[59]
Endoplasmic reticulum aminopeptidase 1 (ERAP1)	OT72S99B	ERAP1_HUMAN	Decreases Expression	[59]
Transcription factor CP2-like protein 1 (TFCP2L1)	OT7QIJ0X	TF2L1_HUMAN	Increases Expression	[59]
Myoferlin (MYOF)	OTRFC3IJ	MYOF_HUMAN	Increases Expression	[59]
Interleukin-1 receptor accessory protein-like 1 (IL1RAPL1)	OTW3T4B2	IRPL1_HUMAN	Decreases Expression	[59]
Tropomodulin-2 (TMOD2)	OTTTUH2W	TMOD2_HUMAN	Increases Expression	[59]
Potassium voltage-gated channel subfamily D member 2 (KCND2)	OTIFUVV7	KCND2_HUMAN	Decreases Expression	[59]
Disintegrin and metalloproteinase domain-containing protein 22 (ADAM22)	OT452ZDC	ADA22_HUMAN	Decreases Expression	[59]
DOMON domain-containing protein FRRS1L (FRRS1L)	OT24ABVC	FRS1L_HUMAN	Decreases Expression	[59]
Peroxisomal sarcosine oxidase (PIPOX)	OTWTCOTN	SOX_HUMAN	Increases Expression	[59]
MyoD family inhibitor domain-containing protein (MDFIC)	OTSRYBWZ	MDFIC_HUMAN	Increases Expression	[59]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 (PLCE1)	OTJISZOX	PLCE1_HUMAN	Increases Expression	[59]
Junctional cadherin 5-associated protein (JCAD)	OT7G1WJW	JCAD_HUMAN	Increases Expression	[59]
Protocadherin-10 (PCDH10)	OT2GIT0E	PCD10_HUMAN	Increases Expression	[59]
Kelch-like protein 14 (KLHL14)	OTYOS55H	KLH14_HUMAN	Increases Expression	[59]
Short transient receptor potential channel 4 (TRPC4)	OTYY9DPV	TRPC4_HUMAN	Decreases Expression	[59]
Hairy/enhancer-of-split related with YRPW motif protein 2 (HEY2)	OTU4J3ZI	HEY2_HUMAN	Increases Expression	[59]
Homeobox expressed in ES cells 1 (HESX1)	OT5E2Z4G	HESX1_HUMAN	Decreases Expression	[59]
Small conductance calcium-activated potassium channel protein 3 (KCNN3)	OT11KYA8	KCNN3_HUMAN	Decreases Expression	[59]
Testin (TES)	OTL8PP6V	TES_HUMAN	Increases Expression	[59]
Sushi domain-containing protein 2 (SUSD2)	OTSJTAZP	SUSD2_HUMAN	Increases Expression	[59]
Transcription factor COE1 (EBF1)	OTZ61YYH	COE1_HUMAN	Increases Expression	[59]
Zinc finger transcription factor Trps1 (TRPS1)	OT7XPPEL	TRPS1_HUMAN	Increases Expression	[59]
Scm-like with four MBT domains protein 1 (SFMBT1)	OTKMZIBW	SMBT1_HUMAN	Decreases Expression	[59]
Krueppel-like factor 15 (KLF15)	OTGMQMVR	KLF15_HUMAN	Increases Expression	[59]
E3 ISG15--protein ligase HERC5 (HERC5)	OTZ5PR39	HERC5_HUMAN	Increases Expression	[59]
Potassium voltage-gated channel subfamily G member 1 (KCNG1)	OTZ9ZRG8	KCNG1_HUMAN	Increases Expression	[59]
Forkhead box protein D3 (FOXD3)	OTXYV6GO	FOXD3_HUMAN	Increases Expression	[59]
Purine-rich element-binding protein gamma (PURG)	OTXPQDWN	PURG_HUMAN	Decreases Expression	[59]
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 (GNG8)	OT9YHSF1	GBG8_HUMAN	Decreases Expression	[59]
F-box only protein 2 (FBXO2)	OTF3677S	FBX2_HUMAN	Increases Expression	[59]
Ribosomal protein S6 kinase alpha-6 (RPS6KA6)	OTTY0FI2	KS6A6_HUMAN	Decreases Expression	[59]
Nocturnin (NOCT)	OTVSYP2D	NOCT_HUMAN	Increases Expression	[59]
Adherens junction-associated protein 1 (AJAP1)	OTAAW121	AJAP1_HUMAN	Increases Expression	[59]
TRAF2 and NCK-interacting protein kinase (TNIK)	OTDZBJ4K	TNIK_HUMAN	Increases Expression	[59]
Cdc42 effector protein 3 (CDC42EP3)	OTUZ3U9Z	BORG2_HUMAN	Decreases Expression	[59]
Disintegrin and metalloproteinase domain-containing protein 28 (ADAM28)	OT3GBVHL	ADA28_HUMAN	Increases Expression	[59]
ETS-related transcription factor Elf-5 (ELF5)	OTLRU8YF	ELF5_HUMAN	Increases Expression	[59]
Procollagen C-endopeptidase enhancer 2 (PCOLCE2)	OTSUEQZ1	PCOC2_HUMAN	Increases Expression	[59]
DENN domain-containing protein 2A (DENND2A)	OT01E1PL	DEN2A_HUMAN	Decreases Expression	[59]
NACHT and WD repeat domain-containing protein 2 (NWD2)	OTN47UBK	NWD2_HUMAN	Increases Expression	[59]
Protein HEG homolog 1 (HEG1)	OT3CUXA7	HEG1_HUMAN	Decreases Expression	[59]
Neurabin-1 (PPP1R9A)	OTJL2TOC	NEB1_HUMAN	Decreases Expression	[59]
RING finger protein 150 (RNF150)	OTAMSBK5	RN150_HUMAN	Increases Expression	[59]
E3 ubiquitin-protein ligase CBL-C (CBLC)	OT3RKZI9	CBLC_HUMAN	Increases Expression	[59]
Frizzled-10 (FZD10)	OTSAENLT	FZD10_HUMAN	Increases Expression	[59]
Apoptosis-associated speck-like protein containing a CARD (PYCARD)	OT67RON3	ASC_HUMAN	Increases Expression	[59]
Sex comb on midleg-like protein 1 (SCML1)	OT7V5DAR	SCML1_HUMAN	Increases Expression	[59]
DNA polymerase iota (POLI)	OTBA4DCE	POLI_HUMAN	Decreases Expression	[59]
LIM and calponin homology domains-containing protein 1 (LIMCH1)	OTYPC4XA	LIMC1_HUMAN	Decreases Expression	[59]
Cystine/glutamate transporter (SLC7A11)	OTKJ6PXW	XCT_HUMAN	Increases Expression	[59]
Catenin delta-2 (CTNND2)	OTYKE30Y	CTND2_HUMAN	Decreases Expression	[59]
Tenascin-N (TNN)	OTQK2AMX	TENN_HUMAN	Increases Expression	[59]
Short transient receptor potential channel 6 (TRPC6)	OT5J7HVM	TRPC6_HUMAN	Increases Expression	[59]
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9 (FUT9)	OTLIJBQY	FUT9_HUMAN	Decreases Expression	[59]
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (PDE10A)	OT74EK7Z	PDE10_HUMAN	Decreases Expression	[59]
Leucine zipper putative tumor suppressor 1 (LZTS1)	OTXXL864	LZTS1_HUMAN	Increases Expression	[59]
C-C motif chemokine 26 (CCL26)	OT2B7HR9	CCL26_HUMAN	Increases Expression	[59]
TBC1 domain family member 30 (TBC1D30)	OTG8HGSI	TBC30_HUMAN	Decreases Expression	[59]
Band 4.1-like protein 3 (EPB41L3)	OTS6CHG2	E41L3_HUMAN	Increases Expression	[59]
Axin-2 (AXIN2)	OTRMGQNU	AXIN2_HUMAN	Increases Expression	[59]
Retinal homeobox protein Rx (RAX)	OTJ3YCE7	RX_HUMAN	Decreases Expression	[59]
Tudor and KH domain-containing protein (TDRKH)	OTV21BN1	TDRKH_HUMAN	Decreases Expression	[59]
Transmembrane emp24 domain-containing protein 5 (TMED5)	OT70W1J8	TMED5_HUMAN	Increases Expression	[59]
C2 domain-containing protein 2 (C2CD2)	OTL1K0OB	C2CD2_HUMAN	Decreases Expression	[59]
Sal-like protein 2 (SALL2)	OTQWI68Q	SALL2_HUMAN	Decreases Expression	[59]
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2)	OTJBDX0Y	VPP2_HUMAN	Decreases Expression	[59]
Beta/gamma crystallin domain-containing protein 1 (CRYBG1)	OTIPDI15	CRBG1_HUMAN	Increases Expression	[59]
Transcription factor HES-2 (HES2)	OTMWY2KV	HES2_HUMAN	Increases Expression	[59]
Intraflagellar transport protein 25 homolog (IFT25)	OTDR1HG6	IFT25_HUMAN	Decreases Expression	[59]
Low-density lipoprotein receptor-related protein 12 (LRP12)	OTRT1UJ7	LRP12_HUMAN	Decreases Expression	[59]
Protein mab-21-like 2 (MAB21L2)	OTZM5VMX	MB212_HUMAN	Decreases Expression	[59]
Protocadherin beta-14 (PCDHB14)	OTFZF1ST	PCDBE_HUMAN	Decreases Expression	[59]
Transcription factor MafB (MAFB)	OTH2N3T8	MAFB_HUMAN	Increases Expression	[59]
Neuropeptide FF receptor 2 (NPFFR2)	OTVI4Q85	NPFF2_HUMAN	Increases Expression	[59]
Beta-secretase 2 (BACE2)	OTO5YQVK	BACE2_HUMAN	Increases Expression	[59]
Glypican-6 (GPC6)	OTNJBESF	GPC6_HUMAN	Decreases Expression	[59]
Adhesion G-protein coupled receptor G1 (ADGRG1)	OTQBB8NT	AGRG1_HUMAN	Decreases Expression	[59]
Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (HS3ST3B1)	OTK53GUD	HS3SB_HUMAN	Decreases Expression	[59]
LHFPL tetraspan subfamily member 6 protein (LHFPL6)	OTY6LHJY	LHPL6_HUMAN	Increases Expression	[59]
Mitochondrial inner membrane protease ATP23 homolog (ATP23)	OT303R2T	ATP23_HUMAN	Increases Expression	[59]
Gap junction alpha-3 protein (GJA3)	OTXV6ETF	CXA3_HUMAN	Increases Expression	[59]
Sulfide:quinone oxidoreductase, mitochondrial (SQOR)	OTTLD0KB	SQOR_HUMAN	Increases Expression	[59]
Cadherin-10 (CDH10)	OTK3D5WP	CAD10_HUMAN	Increases Expression	[59]
Calpain-6 (CAPN6)	OT8K5PR5	CAN6_HUMAN	Decreases Expression	[59]
AP-1 complex subunit mu-2 (AP1M2)	OTUE5YLC	AP1M2_HUMAN	Increases Expression	[59]
Dual specificity protein phosphatase 10 (DUSP10)	OTNG467B	DUS10_HUMAN	Increases Expression	[59]
Collagen alpha-1(XI) chain (COL11A1)	OTB0DRMS	COBA1_HUMAN	Increases Expression	[66]
Neuronal growth regulator 1 (NEGR1)	OT57ECW9	NEGR1_HUMAN	Increases Expression	[66]
Bone morphogenetic protein receptor type-1B (BMPR1B)	OTGFN0OD	BMR1B_HUMAN	Affects Expression	[61]
Huntingtin-interacting protein 1 (HIP1)	OT7AKCFQ	HIP1_HUMAN	Increases Expression	[60]
Homeobox protein Meis2 (MEIS2)	OTG4ADLM	MEIS2_HUMAN	Affects Expression	[61]
T-box transcription factor TBX3 (TBX3)	OTM64N7K	TBX3_HUMAN	Affects Expression	[61]
Baculoviral IAP repeat-containing protein 5 (BIRC5)	OTILXZYL	BIRC5_HUMAN	Decreases Expression	[67]
Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase ST8SIA3 (ST8SIA3)	OTG9MXV9	SIA8C_HUMAN	Affects Expression	[61]
Dual specificity tyrosine-phosphorylation-regulated kinase 3 (DYRK3)	OTX1C2GS	DYRK3_HUMAN	Increases Expression	[60]
Transmembrane and coiled-coil domains protein 2 (TMCC2)	OT0D7IYD	TMCC2_HUMAN	Increases Expression	[60]
Growth arrest and DNA damage-inducible protein GADD45 gamma (GADD45G)	OT8V1J4M	GA45G_HUMAN	Increases Expression	[68]
Cellular tumor antigen p53 (TP53)	OTIE1VH3	P53_HUMAN	Increases Acetylation	[68]
Nuclear factor 1 C-type (NFIC)	OTLMCUIB	NFIC_HUMAN	Affects Expression	[61]
Myb-related protein A (MYBL1)	OTBJMC2P	MYBA_HUMAN	Increases Expression	[60]
Histone H2AX (H2AX)	OT18UX57	H2AX_HUMAN	Increases Expression	[69]
Growth arrest and DNA damage-inducible protein GADD45 alpha (GADD45A)	OTDRV63V	GA45A_HUMAN	Increases Expression	[68]
Interleukin-3 receptor subunit alpha (IL3RA)	OTDC3Y8O	IL3RA_HUMAN	Increases Expression	[60]
G-protein coupled receptor 183 (GPR183)	OTRILX7G	GP183_HUMAN	Decreases Expression	[60]
Cyclin-dependent kinase inhibitor 1 (CDKN1A)	OTQWHCZE	CDN1A_HUMAN	Increases Expression	[70]
Signal transducer and activator of transcription 3 (STAT3)	OTAAGKYZ	STAT3_HUMAN	Increases Acetylation	[71]
OX-2 membrane glycoprotein (CD200)	OTQEQSRT	OX2G_HUMAN	Affects Expression	[61]
Tyrosine-protein phosphatase non-receptor type 9 (PTPN9)	OTNAR1I2	PTN9_HUMAN	Affects Expression	[61]
Cyclin-dependent kinase inhibitor 1B (CDKN1B)	OTNY5LLZ	CDN1B_HUMAN	Increases Expression	[70]
Actin, aortic smooth muscle (ACTA2)	OTEDLG8E	ACTA_HUMAN	Decreases Expression	[67]
Histone H4 (H4C1)	OTB71W46	H4_HUMAN	Increases Acetylation	[72]
Guanylate cyclase soluble subunit alpha-1 (GUCY1A1)	OTPTCBUN	GCYA1_HUMAN	Affects Expression	[61]
Unconventional myosin-Ie (MYO1E)	OTM9YSIZ	MYO1E_HUMAN	Increases Expression	[60]
Cyclin-dependent kinase 5 activator 1 (CDK5R1)	OTJELWK0	CD5R1_HUMAN	Decreases Expression	[60]
Histone H3.1t (H3-4)	OTY6ITYF	H31T_HUMAN	Increases Acetylation	[72]
Rho GTPase-activating protein 31 (ARHGAP31)	OTUYTF4I	RHG31_HUMAN	Affects Expression	[61]
Fidgetin (FIGN)	OTJF6EZR	FIGN_HUMAN	Affects Expression	[61]
NHS-like protein 2 (NHSL2)	OT8U1P8E	NHSL2_HUMAN	Affects Expression	[61]
Failed axon connections homolog (FAXC)	OTU0RGB0	FAXC_HUMAN	Affects Expression	[61]
AT-rich interactive domain-containing protein 2 (ARID2)	OTIRJXWM	ARID2_HUMAN	Affects Expression	[61]
Male-specific lethal 1 homolog (MSL1)	OTXLFYLB	MSL1_HUMAN	Decreases Expression	[60]
Rab11 family-interacting protein 1 (RAB11FIP1)	OT0T71OW	RFIP1_HUMAN	Increases Expression	[60]
Protein lin-28 homolog B (LIN28B)	OTVWP0FN	LN28B_HUMAN	Decreases Expression	[61]
Leucine-rich repeat transmembrane neuronal protein 1 (LRRTM1)	OTKI3IU9	LRRT1_HUMAN	Affects Expression	[61]
Transforming growth factor beta activator LRRC33 (NRROS)	OT9WNOKY	LRC33_HUMAN	Decreases Expression	[60]
tRNA-uridine aminocarboxypropyltransferase 1 (DTWD1)	OT95QT6P	DTWD1_HUMAN	Decreases Expression	[60]
TBC1 domain family member 16 (TBC1D16)	OTPR3C6A	TBC16_HUMAN	Increases Expression	[60]
Transforming growth factor-beta receptor-associated protein 1 (TGFBRAP1)	OT80QNR5	TGFA1_HUMAN	Affects Expression	[61]
Alpha-2,8-sialyltransferase 8B (ST8SIA2)	OTRBBBD8	SIA8B_HUMAN	Affects Expression	[61]
Protein FAN (NSMAF)	OTYNVZ23	FAN_HUMAN	Affects Expression	[61]
Protein Jumonji (JARID2)	OT14UM8H	JARD2_HUMAN	Increases Expression	[60]
ELL-associated factor 2 (EAF2)	OTSOET5L	EAF2_HUMAN	Increases Expression	[60]
Abasic site processing protein HMCES (HMCES)	OTVRDL6U	HMCES_HUMAN	Increases Expression	[60]
Protein FAM163A (FAM163A)	OT0MYZ0F	F163A_HUMAN	Affects Expression	[61]
Bcl-2-modifying factor (BMF)	OT90NSLI	BMF_HUMAN	Increases Expression	[60]
Small integral membrane protein 14 (SMIM14)	OT47IF19	SIM14_HUMAN	Increases Expression	[60]
Sialidase-1 (NEU1)	OTH9BY8Y	NEUR1_HUMAN	Increases Expression	[60]
Partner of Y14 and mago (PYM1)	OTEZ2WUO	PYM1_HUMAN	Decreases Expression	[60]
F-box-like/WD repeat-containing protein TBL1XR1 (TBL1XR1)	OTM3B3OA	TBL1R_HUMAN	Affects Expression	[61]
E3 ubiquitin-protein ligase TRIM8 (TRIM8)	OTS6JFR0	TRIM8_HUMAN	Affects Expression	[61]
Sentrin-specific protease 6 (SENP6)	OT05LLF4	SENP6_HUMAN	Affects Expression	[61]
Tumor protein 63 (TP63)	OT0WOOKQ	P63_HUMAN	Increases Expression	[73]
Popeye domain-containing protein 2 (POPDC2)	OTDAZSY5	POPD2_HUMAN	Affects Expression	[61]
F-box only protein 8 (FBXO8)	OTZNGJGW	FBX8_HUMAN	Affects Expression	[61]
Tumor necrosis factor receptor superfamily member 19 (TNFRSF19)	OTTVT4MB	TNR19_HUMAN	Increases Expression	[60]
AP-5 complex subunit sigma-1 (AP5S1)	OTGS53SC	AP5S1_HUMAN	Decreases Expression	[60]
Pre-mRNA-splicing factor RBM22 (RBM22)	OTFW0IGK	RBM22_HUMAN	Decreases Expression	[60]
Ral guanine nucleotide dissociation stimulator-like 1 (RGL1)	OTY6ZHVA	RGL1_HUMAN	Increases Expression	[60]
Programmed cell death 1 ligand 1 (CD274)	OTJ0VFDL	PD1L1_HUMAN	Increases Expression	[71]
Coiled-coil and C2 domain-containing protein 2A (CC2D2A)	OTFGRGFR	C2D2A_HUMAN	Affects Expression	[61]
Histone deacetylase 9 (HDAC9)	OTO8O0LF	HDAC9_HUMAN	Decreases Expression	[67]
Lactosylceramide alpha-2,3-sialyltransferase (ST3GAL5)	OT27CCUF	SIAT9_HUMAN	Increases Expression	[60]
RING finger protein 24 (RNF24)	OTUZI597	RNF24_HUMAN	Increases Expression	[60]
Phosphatidylinositide phosphatase SAC2 (INPP5F)	OTPKUY50	SAC2_HUMAN	Increases Expression	[60]
DmX-like protein 1 (DMXL1)	OTWVL31L	DMXL1_HUMAN	Increases Expression	[60]
Cystathionine beta-synthase (CBS)	OT46FSKD	CBS_HUMAN	Increases ADR	[57]
N-alpha-acetyltransferase 15, NatA auxiliary subunit (NAA15)	OT53SIZG	NAA15_HUMAN	Increases ADR	[57]
Methylenetetrahydrofolate reductase (MTHFR)	OTUBJSR7	MTHR_HUMAN	Increases ADR	[57]

References

• [1] Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
• [2] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2801).
• [3] Panobinostat FDA Label
• [4] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
• [5] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7489).
• [6] Analysis of gene expression induced by diethylstilbestrol (DES) in human primitive Mullerian duct cells using microarray. Cancer Lett. 2005 Apr 8;220(2):197-210.
• [7] Gene expression profiling in Ishikawa cells: a fingerprint for estrogen active compounds. Toxicol Appl Pharmacol. 2009 Apr 1;236(1):85-96.
• [8] Moving toward integrating gene expression profiling into high-throughput testing: a gene expression biomarker accurately predicts estrogen receptor alpha modulation in a microarray compendium. Toxicol Sci. 2016 May;151(1):88-103.
• [9] Estrogens modulate the gene expression of Wnt-7a in cultured endometrial adenocarcinoma cells. Mol Nutr Food Res. 2006 Apr;50(4-5):368-72. doi: 10.1002/mnfr.200500215.
• [10] Identification of biomarkers and outcomes of endocrine disruption in human ovarian cortex using In Vitro Models. Toxicology. 2023 Feb;485:153425. doi: 10.1016/j.tox.2023.153425. Epub 2023 Jan 5.
• [11] Estrogen effects on tubulin expression and taxane mediated cytotoxicity in prostate cancer cells. Prostate. 2005 Oct 1;65(2):141-50. doi: 10.1002/pros.20246.
• [12] Using a customized DNA microarray for expression profiling of the estrogen-responsive genes to evaluate estrogen activity among natural estrogens and industrial chemicals. Environ Health Perspect. 2004 May;112(7):773-81. doi: 10.1289/ehp.6753.
• [13] Characterization of UDP-glucuronosyltransferases involved in glucuronidation of diethylstilbestrol in human liver and intestine. Chem Res Toxicol. 2012 Dec 17;25(12):2663-9. doi: 10.1021/tx300310k. Epub 2012 Nov 13.
• [14] Effects of diethylstilbestrol on programmed oocyte death and induction of polyovular follicles in neonatal mouse ovaries. Biol Reprod. 2009 Nov;81(5):1002-9.
• [15] Antiestrogens and steroid hormones: substrates of the human P-glycoprotein. Biochem Pharmacol. 1994 Jul 19;48(2):287-92.
• [16] Comparative analysis of human CYP3A4 and rat CYP3A1 induction and relevant gene expression by bisphenol A and diethylstilbestrol: implications for toxicity testing paradigms. Reprod Toxicol. 2013 Jun;37:24-30.
• [17] Reversible inhibition of four important human liver cytochrome P450 enzymes by diethylstilbestrol. Pharmazie. 2011 Mar;66(3):216-21.
• [18] Use of comprehensive screening methods to detect selective human CAR activators. Biochem Pharmacol. 2011 Dec 15;82(12):1994-2007.
• [19] Estrogen-mediated post transcriptional down-regulation of P-glycoprotein in MDR1-transduced human breast cancer cells. Cancer Sci. 2006 Nov;97(11):1198-204. doi: 10.1111/j.1349-7006.2006.00300.x. Epub 2006 Aug 22.
• [20] Assaying estrogenicity by quantitating the expression levels of endogenous estrogen-regulated genes. Environ Health Perspect. 2000 May;108(5):403-12.
• [21] Oestrogenic potencies of Zeranol, oestradiol, diethylstilboestrol, Bisphenol-A and genistein: implications for exposure assessment of potential endocrine disrupters. Hum Reprod. 2001 May;16(5):1037-45.
• [22] Estrogenic endocrine disruptive components interfere with calcium handling and differentiation of human trophoblast cells. J Cell Biochem. 2003 Jul 1;89(4):755-70.
• [23] Development and validation of a fluorescence HPLC-based screening assay for inhibition of human estrogen sulfotransferase. Anal Biochem. 2006 Oct 1;357(1):85-92.
• [24] Cytotoxic effects and aromatase inhibition by xenobiotic endocrine disrupters alone and in combination. Toxicol Appl Pharmacol. 2007 Jul 15;222(2):129-40.
• [25] Epigenetic influences of low-dose bisphenol A in primary human breast epithelial cells. Toxicol Appl Pharmacol. 2010 Oct 15;248(2):111-21.
• [26] Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11). Toxicol Sci. 2013 Dec;136(2):328-43.
• [27] Oxidative stress mechanisms do not discriminate between genotoxic and nongenotoxic liver carcinogens. Chem Res Toxicol. 2015 Aug 17;28(8):1636-46.
• [28] Estrogen receptor alpha (ER)-mediated coregulator binding and gene expression discriminates the toxic ER agonist diethylstilbestrol (DES) from the endogenous ER agonist 17-estradiol (E2). Cell Biol Toxicol. 2020 Oct;36(5):417-435. doi: 10.1007/s10565-020-09516-6. Epub 2020 Feb 22.
• [29] Estrogens and hypertension: effect of discontinuing estrogens on blood pressure, exchangeable sodium, and the renin-aldosterone system. Am J Med Sci. 1978 Jul-Aug;276(1):33-55.
• [30] Quantitative analysis of gene expression changes in response to genotoxic compounds. Toxicol In Vitro. 2017 Mar;39:15-28. doi: 10.1016/j.tiv.2016.11.004. Epub 2016 Nov 5.
• [31] Prolactin-secreting pituitary adenoma: occurrence following prenatal exposure to diethylstilbestrol. Cleve Clin Q. 1982 Winter;49(4):249-54. doi: 10.3949/ccjm.49.4.249.
• [32] Genomic integration and ligand-dependent activation of the human estrogen receptor in the crustacean Daphnia magna. PLoS One. 2018 Jun 8;13(6):e0198023. doi: 10.1371/journal.pone.0198023. eCollection 2018.
• [33] Human sex hormone-binding globulin binding affinities of 125 structurally diverse chemicals and comparison with their binding to androgen receptor, estrogen receptor, and -fetoprotein. Toxicol Sci. 2015 Feb;143(2):333-48. doi: 10.1093/toxsci/kfu231. Epub 2014 Oct 27.
• [34] Cell-transforming activity and estrogenicity of bisphenol-A and 4 of its analogs in mammalian cells. Int J Cancer. 2001 Jul 1;93(1):20-5. doi: 10.1002/ijc.1303.
• [35] Insulin-like growth factor binding protein-6 inhibits prostate cancer cell proliferation: implication for anticancer effect of diethylstilbestrol in hormone refractory prostate cancer. Br J Cancer. 2005 Apr 25;92(8):1538-44. doi: 10.1038/sj.bjc.6602520.
• [36] Elevated serum cathepsin B1 and vaginal pathology after prenatal DES exposure. Obstet Gynecol. 1978 Sep;52(3):321-7.
• [37] Stilbene-based inhibitors of estrone sulfatase with a dual mode of action in human breast cancer cells. Arch Pharm (Weinheim). 2004 Dec;337(12):634-44. doi: 10.1002/ardp.200400904.
• [38] Effect of anti-estrogens on the androgen receptor activity and cell proliferation in prostate cancer cells. Urol Res. 2004 Dec;32(6):406-10. doi: 10.1007/s00240-004-0424-8. Epub 2004 Aug 14.
• [39] The inhibitory effects of flavonoids and antiestrogens on the Glut1 glucose transporter in human erythrocytes. Chem Biol Interact. 2003 Dec 15;146(3):225-35. doi: 10.1016/j.cbi.2003.06.001.
• [40] Identification of estrogen-responsive genes by complementary deoxyribonucleic acid microarray and characterization of a novel early estrogen-induced gene: EEIG1. Mol Endocrinol. 2004 Feb;18(2):402-11. doi: 10.1210/me.2003-0202. Epub 2003 Nov 6.
• [41] Establishment of a 13 genes-based molecular prediction score model to discriminate the neurotoxic potential of food relevant-chemicals. Toxicol Lett. 2022 Feb 1;355:1-18. doi: 10.1016/j.toxlet.2021.10.013. Epub 2021 Nov 5.
• [42] A HOXA10 estrogen response element (ERE) is differentially regulated by 17 beta-estradiol and diethylstilbestrol (DES). J Mol Biol. 2004 Jul 23;340(5):1013-23. doi: 10.1016/j.jmb.2004.05.052.
• [43] Endocrine regulation of HOX genes. Endocr Rev. 2006 Jun;27(4):331-55. doi: 10.1210/er.2005-0018. Epub 2006 Apr 21.
• [44] Xeno-oestrogens and phyto-oestrogens are alternative ligands for the androgen receptor. Asian J Androl. 2010 Jul;12(4):535-47. doi: 10.1038/aja.2010.14. Epub 2010 May 3.
• [45] Apoptotic and anti-proliferative effects of 17beta-estradiol and 17beta-estradiol-like compounds in the Hep3B cell line. Mol Cell Biochem. 2006 Oct;290(1-2):1-7. doi: 10.1007/s11010-005-9000-y. Epub 2006 Aug 19.
• [46] 4-Hydroxytamoxifen binds to and deactivates the estrogen-related receptor gamma. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8880-4. doi: 10.1073/pnas.151244398. Epub 2001 Jul 10.
• [47] Effect of estrogen-active compounds on the expression of RACK1 and immunological implications. Arch Toxicol. 2020 Jun;94(6):2081-2095. doi: 10.1007/s00204-020-02756-9. Epub 2020 Apr 23.
• [48] miRNA-34b as a tumor suppressor in estrogen-dependent growth of breast cancer cells. Breast Cancer Res. 2011;13(6):R116. doi: 10.1186/bcr3059. Epub 2011 Nov 23.
• [49] A Gene Expression Biomarker Predicts Heat Shock Factor 1 Activation in a Gene Expression Compendium. Chem Res Toxicol. 2021 Jul 19;34(7):1721-1737. doi: 10.1021/acs.chemrestox.0c00510. Epub 2021 Jun 25.
• [50] Activation of kinase pathways in MCF-7 cells by 17beta-estradiol and structurally diverse estrogenic compounds. J Steroid Biochem Mol Biol. 2006 Feb;98(2-3):122-32. doi: 10.1016/j.jsbmb.2005.08.018. Epub 2006 Jan 18.
• [51] Improved assays for xenosensor activation based on reverse transfection. Toxicol In Vitro. 2015 Oct;29(7):1759-65. doi: 10.1016/j.tiv.2015.07.011. Epub 2015 Jul 14.
• [52] In utero exposure to diethylstilbestrol (DES) or bisphenol-A (BPA) increases EZH2 expression in the mammary gland: an epigenetic mechanism linking endocrine disruptors to breast cancer. Horm Cancer. 2010 Jun;1(3):146-55. doi: 10.1007/s12672-010-0015-9.
• [53] GPER1 links estrogens to centrosome amplification and chromosomal instability in human colon cells. Life Sci Alliance. 2022 Nov 16;6(1):e202201499. doi: 10.26508/lsa.202201499. Print 2023 Jan.
• [54] Validation of a new yeast-based reporter assay consisting of human estrogen receptors alpha/beta and coactivator SRC-1: application for detection of estrogenic activity in environmental samples. Environ Toxicol. 2009 Oct;24(5):513-21. doi: 10.1002/tox.20473.
• [55] Prediction of the combined effects of multiple estrogenic chemicals on MCF-7 human breast cancer cells and a preliminary molecular exploration of the estrogenic proliferative effects and related gene expression. Ecotoxicol Environ Saf. 2018 Sep 30;160:1-9. doi: 10.1016/j.ecoenv.2018.05.025. Epub 2018 May 21.
• [56] Sulfation of environmental estrogen-like chemicals by human cytosolic sulfotransferases. Biochem Biophys Res Commun. 2000 Jan 7;267(1):80-4. doi: 10.1006/bbrc.1999.1935.
• [57] ADReCS-Target: target profiles for aiding drug safety research and application. Nucleic Acids Res. 2018 Jan 4;46(D1):D911-D917. doi: 10.1093/nar/gkx899.
• [58] Cytochrome P450-mediated metabolism of tumour promoters modifies the inhibition of intercellular communication: a modified assay for tumour promotion. Carcinogenesis. 1993 Nov;14(11):2365-71. doi: 10.1093/carcin/14.11.2365.
• [59] A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors. Arch Toxicol. 2015 Sep;89(9):1599-618.
• [60] Development and validation of the TGx-HDACi transcriptomic biomarker to detect histone deacetylase inhibitors in human TK6 cells. Arch Toxicol. 2021 May;95(5):1631-1645. doi: 10.1007/s00204-021-03014-2. Epub 2021 Mar 26.
• [61] The Bromodomain Inhibitor JQ1 and the Histone Deacetylase Inhibitor Panobinostat Synergistically Reduce N-Myc Expression and Induce Anticancer Effects. Clin Cancer Res. 2016 May 15;22(10):2534-44. doi: 10.1158/1078-0432.CCR-15-1666. Epub 2016 Jan 5.
• [62] Protein methyltransferases as a target class for drug discovery. Nat Rev Drug Discov. 2009 Sep;8(9):724-32.
• [63] Panobinostat for the treatment of multiple myeloma: the evidence to date. J Blood Med. 2015 Oct 8;6:269-76.
• [64] Panobinostat for the treatment of relapsed or relapsed/refractory multiple myeloma: pharmacology and clinical outcomes. Expert Rev Clin Pharmacol. 2016;9(1):35-48.
• [65] Highly active combination of BRD4 antagonist and histone deacetylase inhibitor against human acute myelogenous leukemia cells. Mol Cancer Ther. 2014 May;13(5):1142-54.
• [66] Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Toxukn and STOP-Toxukk tests. Arch Toxicol. 2017 Feb;91(2):839-864.
• [67] Comparison of the antifibrotic effects of the pan-histone deacetylase-inhibitor panobinostat versus the IPF-drug pirfenidone in fibroblasts from patients with idiopathic pulmonary fibrosis. PLoS One. 2018 Nov 27;13(11):e0207915. doi: 10.1371/journal.pone.0207915. eCollection 2018.
• [68] SIRT1 activation enhances HDAC inhibition-mediated upregulation of GADD45G by repressing the binding of NF-B/STAT3 complex to its promoter in malignant lymphoid cells. Cell Death Dis. 2013 May 16;4(5):e635. doi: 10.1038/cddis.2013.159.
• [69] Resveratrol sensitizes acute myelogenous leukemia cells to histone deacetylase inhibitors through reactive oxygen species-mediated activation of the extrinsic apoptotic pathway. Mol Pharmacol. 2012 Dec;82(6):1030-41. doi: 10.1124/mol.112.079624. Epub 2012 Aug 24.
• [70] Mitochondrial Bax translocation partially mediates synergistic cytotoxicity between histone deacetylase inhibitors and proteasome inhibitors in glioma cells. Neuro Oncol. 2008 Jun;10(3):309-19. doi: 10.1215/15228517-2007-063. Epub 2008 Apr 29.
• [71] Essential role of HDAC6 in the regulation of PD-L1 in?melanoma. Mol Oncol. 2016 May;10(5):735-750. doi: 10.1016/j.molonc.2015.12.012. Epub 2016 Jan 6.
• [72] A systematic assessment of radiation dose enhancement by 5-Aza-2'-deoxycytidine and histone deacetylase inhibitors in head-and-neck squamous cell carcinoma. Int J Radiat Oncol Biol Phys. 2009 Mar 1;73(3):904-12. doi: 10.1016/j.ijrobp.2008.10.032.
• [73] Induction of TAp63 by histone deacetylase inhibitors. Biochem Biophys Res Commun. 2010 Jan 22;391(4):1748-51. doi: 10.1016/j.bbrc.2009.12.147. Epub 2009 Dec 30.