Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMB4OLE)

Drug Name
Propofol Drug Info
Synonyms
Ampofol; Aquafol; Diisopropylphenol; Dipravan; Diprivan; Disoprivan; Disoprofol; Fresofol; Ivofol; PFL; Propofolum; Rapinovet; Recofol; Abbott Brand of Propofol; Alpha Brand of Propofol; Astra Brand of Propofol; AstraZeneca Brand of Propofol; Braun Brand of Propofol; Curamed Brand of Propofol; Diprivan Injectable emulsion; Fresenius Brand of Propofol; Fresenius Kabi Brand of Propofol; Juste Brand of Propofol; Parnell Brand of Propofol; Pisa Brand of Propofol; Propofol Abbott; Propofol Fresenius; Propofol MCT; Propofol Rovi; Propofolum [Latin]; Rovi Brand of Propofol; Schering Brand of Propofol; Zeneca Brand of Propofol; AM-149; DDS-04F; Diprivan (TN); Propofol IDD-D; Propofol-Lipuro; ZD-0859; Ghl.PD_Mitscher_leg0.558; Propofol [USAN:INN:BAN]; Propofol (JAN/USAN/INN); Propofol(2,6-Diisopropylphenol); 2, 6-Diisopropylphenol; 2,6 Diisopropylphenol; 2,6-Bis(1-methylethyl)phenol; 2,6-Bis(Isopropyl)-phenol; 2,6-DIISOPROPYLPHENOL; 2,6-Diisopropyl phenol; 2,6-Diisopropylphenol; 2,6-bis(1-methylethyl)-phenol; 2,6-di(propan-2-yl)phenol
Indication
Disease Entry ICD 11 Status REF
Anaesthesia 9A78.6 Approved [1]
Leukemia Approved [2]
Traumatic brain injury NA07.Z Approved [2]
Coronavirus Disease 2019 (COVID-19) 1D6Y Investigative [3]
Therapeutic Class
Hypnotics and Sedatives
Cross-matching ID
PubChem CID
4943
ChEBI ID
CHEMBL526
CAS Number
CAS 2078-54-8
TTD Drug ID
DMB4OLE
VARIDT Drug ID
DR00424
INTEDE Drug ID
DR1365
ACDINA Drug ID
D01367

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Fatty acid amide hydrolase (FAAH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Thiopental DMGP8AX Anaesthesia 9A78.6 Approved [18]
JNJ-42165279 DM72GZO Anxiety disorder 6B00-6B0Z Phase 2 [19]
SSR411298 DMGTB2Q Major depressive disorder 6A70.3 Phase 2 [20]
IW-6118 DMP42W1 Inflammation 1A00-CA43.1 Phase 2 [21]
PF-04457845 DMPRYU1 Liver disease DB90-BD99 Phase 2 [22]
IPI-940 DMEIM5G Pain MG30-MG3Z Phase 1 [23]
PMID29053063-Compound-11d DMDRK68 N. A. N. A. Patented [24]
Piperazine carbamic compound 1 DMZSYU4 N. A. N. A. Patented [24]
Piperazine carbamic compound 2 DMMQ0ZO N. A. N. A. Patented [24]
Pyrazole derivative 82 DMETCI3 N. A. N. A. Patented [24]
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Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [25]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [26]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [27]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [28]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [29]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [30]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [31]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [32]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [26]
Verapamil DMA7PEW Angina pectoris BA40 Approved [11]
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Drug(s) Metabolized By Cytochrome P450 1A2 (CYP1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [33]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [34]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [35]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [36]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [37]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [38]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [31]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [39]
Verapamil DMA7PEW Angina pectoris BA40 Approved [40]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [41]
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Drug(s) Metabolized By UDP-glucuronosyltransferase 1A1 (UGT1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [42]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [43]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [44]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [45]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [46]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [47]
Mycophenolate mofetil DMPQAGE Hepatosplenic T-cell lymphoma Approved [48]
Metronidazole DMTIVEN Abscess Approved [49]
Ethanol DMDRQZU Chronic pain MG30 Approved [50]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [51]
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Drug(s) Metabolized By Cytochrome P450 2A6 (CYP2A6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [33]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [52]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [53]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [29]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [52]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [54]
Metronidazole DMTIVEN Abscess Approved [55]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [56]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [52]
Lidocaine DML4ZOT Anaesthesia 9A78.6 Approved [52]
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Drug(s) Metabolized By Cytochrome P450 2D6 (CYP2D6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [57]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [58]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [59]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [29]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [11]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [60]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [61]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [62]
Propranolol DM79NTF Angina pectoris BA40 Approved [63]
Amitriptyline DMK7F9S Depression 6A70-6A7Z Approved [64]
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Drug(s) Metabolized By Cytochrome P450 2E1 (CYP2E1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Folic Acid DMEMBJC Colorectal carcinoma Approved [65]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [66]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [53]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [67]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [68]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [39]
Verapamil DMA7PEW Angina pectoris BA40 Approved [52]
Estrone DM5T6US Acne vulgaris ED80 Approved [69]
Ethanol DMDRQZU Chronic pain MG30 Approved [70]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [71]
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Drug(s) Metabolized By Cytochrome P450 2C18 (CYP2C18)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [52]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [72]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [52]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [73]
Diazepam DM08E9O Alcohol withdrawal Approved [74]
Methadone DMTW6IU Advanced cancer 2A00-2F9Z Approved [75]
Dapsone DM4LT8A Acne vulgaris ED80 Approved [76]
Lidocaine DML4ZOT Anaesthesia 9A78.6 Approved [52]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [77]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [78]
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Drug(s) Metabolized By Cytochrome P450 2C8 (CYP2C8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [33]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [79]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [79]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [52]
Verapamil DMA7PEW Angina pectoris BA40 Approved [80]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [81]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [82]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [79]
Mycophenolate mofetil DMPQAGE Hepatosplenic T-cell lymphoma Approved [83]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [84]
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Drug(s) Metabolized By Cytochrome P450 2C9 (CYP2C9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Progesterone DMUY35B Amenorrhea GA20.0 Approved [85]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [86]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [87]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [52]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [88]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [52]
Verapamil DMA7PEW Angina pectoris BA40 Approved [89]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [90]
Estrone DM5T6US Acne vulgaris ED80 Approved [91]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [92]
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Drug(s) Metabolized By Cytochrome P450 2B6 (CYP2B6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [93]
Verapamil DMA7PEW Angina pectoris BA40 Approved [52]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [94]
Estrone DM5T6US Acne vulgaris ED80 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [96]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [97]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [98]
Amitriptyline DMK7F9S Depression 6A70-6A7Z Approved [99]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [52]
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Drug(s) Metabolized By Mephenytoin 4-hydroxylase (CYP2C19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [100]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [85]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [101]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [102]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [52]
Verapamil DMA7PEW Angina pectoris BA40 Approved [103]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [92]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [104]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [52]
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Drug(s) Metabolized By UDP-glucuronosyltransferase 1A9 (UGT1A9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [105]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [106]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [11]
Mycophenolate mofetil DMPQAGE Hepatosplenic T-cell lymphoma Approved [108]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [11]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [109]
Nateglinide DMLK2QH Diabetic complication 5A2Y Approved [11]
Haloperidol DM96SE0 Delirium Approved [11]
Naproxen DMZ5RGV Bursitis Approved [110]
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Drug(s) Metabolized By UDP-glucuronosyltransferase 1A6 (UGT1A6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [111]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [112]
Mycophenolate mofetil DMPQAGE Hepatosplenic T-cell lymphoma Approved [48]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [113]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [114]
Naproxen DMZ5RGV Bursitis Approved [110]
Deferiprone DMS2M7O Beta thalassemia 3A50.2 Approved [115]
ANDROSTERONE DMITJAK N. A. N. A. Phase 3 [116]
BCP-13498 DM2BO9W N. A. N. A. Phase 2 [117]
LM-94 DMW3QGJ N. A. N. A. Phase 1/2 [118]
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Drug(s) Affected By Glutamate dehydrogenase 1, mitochondrial (GLUD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [119]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [120]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [121]
Testosterone DM7HUNW Hot flushes GA30 Approved [122]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [122]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [123]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [16]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [124]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [125]
Capsaicin DMGMF6V Back pain ME84.Z Approved [126]
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Drug(s) Affected By Progonadoliberin-1 (GNRH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [127]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [128]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [129]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [130]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [131]
ACYLINE DM9GRTK Prostate cancer 2C82.0 Phase 2 [132]
3R14S-OCHRATOXIN A DM2KEW6 Discovery agent N.A. Investigative [133]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [134]
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Drug(s) Affected By Interleukin-2 receptor subunit alpha (IL2RA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [135]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [136]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [137]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [138]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [139]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [140]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [141]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [124]
Folic Acid DMEMBJC Colorectal carcinoma Approved [142]
Clozapine DMFC71L Schizophrenia 6A20 Approved [143]
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Drug(s) Affected By Guanine nucleotide-binding protein G(i) subunit alpha-2 (GNAI2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [144]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [145]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [124]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [125]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [146]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [147]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [148]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [149]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [150]
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Drug(s) Affected By Hepatocyte growth factor receptor (MET)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cabozantinib DMIYDT4 Medullary thyroid gland carcinoma Approved [151]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [152]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [153]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [153]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [153]
Methotrexate DM2TEOL Anterior urethra cancer Approved [154]
Quercetin DM3NC4M Obesity 5B81 Approved [119]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [153]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [155]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [154]
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Drug(s) Affected By Small ribosomal subunit protein uS2 (RPSA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [156]
Quercetin DM3NC4M Obesity 5B81 Approved [157]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [158]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [159]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [125]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [160]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [161]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [162]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [131]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [163]
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Drug(s) Affected By Matrilysin (MMP7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [164]
Quercetin DM3NC4M Obesity 5B81 Approved [165]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [166]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [167]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [168]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [123]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [169]
Clozapine DMFC71L Schizophrenia 6A20 Approved [170]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [171]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [172]
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Drug(s) Affected By Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [173]
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [174]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [175]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [176]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [177]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [178]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [177]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [158]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [179]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [180]
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Drug(s) Affected By Proto-oncogene tyrosine-protein kinase Src (SRC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Bosutinib DMTI8YE Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [181]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [182]
Methotrexate DM2TEOL Anterior urethra cancer Approved [183]
Quercetin DM3NC4M Obesity 5B81 Approved [184]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [180]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [185]
Plicamycin DM7C8YV Hypercalcaemia 5B91.0 Approved [186]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [124]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [125]
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Drug(s) Affected By Metalloproteinase inhibitor 2 (TIMP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [129]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [187]
Selenium DM25CGV N. A. N. A. Approved [188]
Quercetin DM3NC4M Obesity 5B81 Approved [189]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [190]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [191]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [192]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [193]
Tetracaine DM9J6C2 Spinal anesthesia MB40.3 Approved [194]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [195]
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Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [196]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [197]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [198]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [199]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [200]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [201]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [202]
Gefitinib DM15F0X Colon adenocarcinoma Approved [203]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [204]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [205]
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Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [206]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [197]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [207]
Paclitaxel DMLB81S Breast carcinoma Approved [208]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [209]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [196]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [210]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [211]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [199]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [200]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Macrosialin (CD68)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [211]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [178]
Methotrexate DM2TEOL Anterior urethra cancer Approved [212]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [120]
Testosterone DM7HUNW Hot flushes GA30 Approved [122]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [122]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [123]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [14]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [213]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [214]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Carbonic anhydrase 5A, mitochondrial (CA5A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [145]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [124]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [215]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [216]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [217]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [218]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (PTEN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [219]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [220]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [221]
Methotrexate DM2TEOL Anterior urethra cancer Approved [183]
Cladribine DM3JDRP Hairy cell leukaemia 2A82.2 Approved [222]
Quercetin DM3NC4M Obesity 5B81 Approved [223]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [158]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [224]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [225]
Testosterone DM7HUNW Hot flushes GA30 Approved [226]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein SET (SET)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [120]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [180]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [227]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [145]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [130]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [125]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [146]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [228]
BIBW 2992 DMTKD7Q Non-small-cell lung cancer 2C25.Y Approved [229]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By RNA-binding protein EWS (EWSR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [129]
Selenium DM25CGV N. A. N. A. Approved [144]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [230]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [231]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [125]
Benzatropine DMF7EXL Parkinsonian disorder Approved [176]
Romidepsin DMT5GNL Cutaneous T-cell lymphoma 2B01 Approved [232]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [233]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [149]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (MGAT5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [135]
Quercetin DM3NC4M Obesity 5B81 Approved [173]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [234]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [130]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [216]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [235]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [127]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [149]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [236]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mothers against decapentaplegic homolog 2 (SMAD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [156]
Quercetin DM3NC4M Obesity 5B81 Approved [237]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [238]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [239]
Panobinostat DM58WKG Chronic graft versus host disease Approved [240]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [241]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [124]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [125]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [242]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transmembrane channel-like protein 6 (TMC6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [135]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [238]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [243]
Testosterone DM7HUNW Hot flushes GA30 Approved [122]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [193]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [145]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [124]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [214]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [244]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [216]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Polycystin-1-like protein 3 (PKD1L3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [245]
Drug(s) Affected By Uncharacterized protein C10orf67, mitochondrial (C10ORF67)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic DMTL2Y1 N. A. N. A. Approved [246]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [245]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [247]
Drug(s) Affected By Pinin (PNN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [238]
Leflunomide DMR8ONJ Arthritis FA20 Approved [248]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [249]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [125]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [250]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [216]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [129]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [233]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [251]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein turtle homolog B (IGSF9B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [124]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [147]
Arsenic DMTL2Y1 N. A. N. A. Approved [252]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [127]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [149]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [253]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [245]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [247]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Mitochondrial pyruvate carrier 1 (MPC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [119]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [120]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [254]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [145]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [16]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [130]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [255]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [244]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [216]
Arsenic DMTL2Y1 N. A. N. A. Approved [252]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Fatty acid amide hydrolase (FAAH) TTDP1UC NOUNIPROTAC Inhibitor [4]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Substrate [5]
Cytochrome P450 2E1 (CYP2E1) DEVDYN7 CP2E1_HUMAN Substrate [6]
Cytochrome P450 2D6 (CYP2D6) DECB0K3 CP2D6_HUMAN Substrate [7]
Cytochrome P450 2C9 (CYP2C9) DE5IED8 CP2C9_HUMAN Substrate [5]
UDP-glucuronosyltransferase 1A1 (UGT1A1) DEYGVN4 UD11_HUMAN Substrate [8]
Mephenytoin 4-hydroxylase (CYP2C19) DEGTFWK CP2CJ_HUMAN Substrate [9]
Cytochrome P450 2A6 (CYP2A6) DEJVYAZ CP2A6_HUMAN Substrate [9]
Cytochrome P450 1A2 (CYP1A2) DEJGDUW CP1A2_HUMAN Substrate [6]
Cytochrome P450 2B6 (CYP2B6) DEPKLMQ CP2B6_HUMAN Substrate [10]
Cytochrome P450 2C8 (CYP2C8) DES5XRU CP2C8_HUMAN Substrate [9]
UDP-glucuronosyltransferase 1A9 (UGT1A9) DE85D2P UD19_HUMAN Substrate [11]
UDP-glucuronosyltransferase 1A6 (UGT1A6) DESD26P UD16_HUMAN Substrate [12]
Cytochrome P450 2C18 (CYP2C18) DEZMWRE CP2CI_HUMAN Substrate [9]
Oleamide hydrolase 1 (FAAH) DEUM1EX FAAH1_HUMAN Substrate [13]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (MGAT5) OTU4DD4G MGT5A_HUMAN Gene/Protein Processing [14]
Carbonic anhydrase 5A, mitochondrial (CA5A) OTP9M7VW CAH5A_HUMAN Gene/Protein Processing [15]
E3 ubiquitin-protein ligase UHRF1 OTBNJUF2 UHRF1_HUMAN Gene/Protein Processing [15]
Glutamate dehydrogenase 1, mitochondrial (GLUD1) OTXKOCUH DHE3_HUMAN Gene/Protein Processing [16]
Guanine nucleotide-binding protein G(i) subunit alpha-2 (GNAI2) OTTLGRGH GNAI2_HUMAN Gene/Protein Processing [15]
Hepatocyte growth factor receptor (MET) OT7K55MU MET_HUMAN Gene/Protein Processing [14]
Interleukin-2 receptor subunit alpha (IL2RA) OT0MWCHG IL2RA_HUMAN Protein Interaction/Cellular Processes [17]
Leucine-rich colipase-like protein 1 (LRCOL1) OTDXBZF8 LRCL1_HUMAN Gene/Protein Processing [15]
Macrosialin (CD68) OTOYEY3J CD68_HUMAN Gene/Protein Processing [14]
Matrilysin (MMP7) OTVT3SEJ MMP7_HUMAN Gene/Protein Processing [14]

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