General Information of Drug (ID: DMC0GSJ)

Drug Name
Efavirenz Drug Info
Synonyms
EFV; EFZ; Eravirenz; Stocrin; Sustiva; DMP 266; L 743726; DMP-266; L-741211; L-743725; L-743726; Stocrin (TN); Strocin (TM); Sustiva (TM); Sustiva (TN); Efavirenz (JAN/INN); L-743,726; Zoxazin-2-one; Efavirenz, (S)-isomer; Met-SDF-1.beta. & Efavirenz; Met-Stromal Cell-derived Factor-1.beta. (Human) & Efavirenz; (-)-Efavirenz; (4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; (4S)-6-Chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one; (4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one; (4S)-6-chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazin-2-one; (S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-ben; (S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; (S)-6-Chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one; 2H-3,1-Benzoxazin-2-one, 6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-, (4S)-(9; 6-chloro-4-(2-cyclopropyl-1-ethynyl)-4-trifluoromethyl-(4S)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one
Indication
Disease Entry ICD 11 Status REF
Human immunodeficiency virus infection 1C62 Approved [1]
Therapeutic Class
Anti-HIV Agents
Cross-matching ID
PubChem CID
64139
ChEBI ID
CHEMBL223228
CAS Number
CAS 154598-52-4
TTD Drug ID
DMC0GSJ
VARIDT Drug ID
DR00412
INTEDE Drug ID
DR0560
ACDINA Drug ID
D00222

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [14]
Nevirapine DM6HX9B Human immunodeficiency virus infection 1C62 Approved [15]
Zalcitabine DMH7MUV Human immunodeficiency virus infection 1C62 Approved [16]
Tenofovir DM1IS6U Chronic hepatitis B virus infection Approved [14]
Lamivudine DMI347A Chronic HBV infection 1E51.0Z Approved [2]
Abacavir DMMN36E Human immunodeficiency virus infection 1C62 Approved [17]
Delavirdine DM3NF5G Human immunodeficiency virus infection 1C62 Approved [2]
Rilpivirine DMJ0QOW Human immunodeficiency virus infection 1C62 Approved [18]
Etravirine DMGV8QU Human immunodeficiency virus-1 infection 1C62 Approved [19]
MK-1439 DM215WE Human immunodeficiency virus infection 1C62 Approved [20]
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Drug(s) Transported By P-glycoprotein 1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [4]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [21]
Methotrexate DM2TEOL Anterior urethra cancer Approved [22]
Folic Acid DMEMBJC Colorectal carcinoma Approved [23]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [22]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [22]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [24]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [22]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [25]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [26]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [27]
Folic Acid DMEMBJC Colorectal carcinoma Approved [28]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [29]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [30]
Ezetimibe DM7A8TW Atherosclerosis BD40 Approved [31]
Glibenclamide DM8JXPZ Diabetic complication 5A2Y Approved [32]
Morphine DMRMS0L Advanced cancer 2A00-2F9Z Approved [33]
Cefadroxil DMMC345 Bacterial infection 1A00-1C4Z Approved [34]
Teniposide DMLW57T Acute lymphoblastic leukaemia 2A85 Approved [35]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [36]
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Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [37]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [38]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [39]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [40]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [41]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [42]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [43]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [44]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [38]
Verapamil DMA7PEW Angina pectoris BA40 Approved [45]
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Drug(s) Metabolized By Cytochrome P450 1A2 (CYP1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [46]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [47]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [48]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [49]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [50]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [51]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [43]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [52]
Verapamil DMA7PEW Angina pectoris BA40 Approved [53]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [54]
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Drug(s) Metabolized By Cytochrome P450 2B6 (CYP2B6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [55]
Verapamil DMA7PEW Angina pectoris BA40 Approved [56]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [57]
Estrone DM5T6US Acne vulgaris ED80 Approved [58]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [59]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [60]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [61]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [62]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [63]
Amitriptyline DMK7F9S Depression 6A70-6A7Z Approved [64]
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Drug(s) Affected By Cytochrome P450 2C19 (CYP2C19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [65]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [66]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [67]
Chloramphenicol DMFXEWT Bacterial infection 1A00-1C4Z Approved [68]
Capsaicin DMGMF6V Back pain ME84.Z Approved [69]
Pentamidine DMHZJCG African trypanosomiasis 1F51 Approved [70]
Stiripentol DMMSDOY Dravet syndrome 8A61.11 Approved [71]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [70]
Desipramine DMT2FDC Attention deficit hyperactivity disorder 6A05.Z Approved [66]
Amitriptyline DMK7F9S Depression 6A70-6A7Z Approved [72]
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Drug(s) Affected By Bile salt export pump (ABCB11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [73]
Ezetimibe DM7A8TW Atherosclerosis BD40 Approved [10]
Glipizide DMZA5PQ Diabetic complication 5A2Y Approved [10]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [74]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [73]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [10]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [75]
Gefitinib DM15F0X Colon adenocarcinoma Approved [73]
Drospirenone DM1A9W3 Acne vulgaris ED80 Approved [76]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [73]
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Drug(s) Affected By Dynamin-1-like protein (DNM1L)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [77]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [78]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [79]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [80]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [81]
Ethanol DMDRQZU Chronic pain MG30 Approved [82]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [83]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [77]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [84]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [85]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [86]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [87]
Quercetin DM3NC4M Obesity 5B81 Approved [88]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [89]
Remdesivir DMBFZ6L Coronavirus Disease 2019 (COVID-19) 1D6Y Approved [90]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [91]
Panobinostat DM58WKG Chronic graft versus host disease Approved [92]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [93]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [94]
Testosterone DM7HUNW Hot flushes GA30 Approved [95]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [96]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [78]
Selenium DM25CGV N. A. N. A. Approved [97]
Testosterone DM7HUNW Hot flushes GA30 Approved [95]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [98]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [81]
Ethanol DMDRQZU Chronic pain MG30 Approved [82]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [99]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [100]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [101]
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Drug(s) Affected By Mitofusin-2 (MFN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [89]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [102]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [103]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [81]
Melatonin DMKWFBT Depression 6A70-6A7Z Approved [104]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [100]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [105]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [106]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [107]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [108]
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Drug(s) Affected By Thyroglobulin (TG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [109]
Propylthiouracil DM6D7N8 Hyperthyroidism 5A02 Approved [110]
Nevirapine DM6HX9B Human immunodeficiency virus infection 1C62 Approved [111]
Testosterone DM7HUNW Hot flushes GA30 Approved [112]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [112]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [113]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [114]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [115]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [116]
Arsenic DMTL2Y1 N. A. N. A. Approved [117]
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Drug(s) Affected By Albumin (ALB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [100]
Sulfamethoxazole DMB08GE Acute otitis media AB00 Approved [72]
Tolbutamide DM02AWV Advanced cancer 2A00-2F9Z Approved [118]
Diazepam DM08E9O Alcohol withdrawal Approved [119]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [120]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [121]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [122]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [123]
Methotrexate DM2TEOL Anterior urethra cancer Approved [124]
Quercetin DM3NC4M Obesity 5B81 Approved [125]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [126]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [127]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [128]
Methotrexate DM2TEOL Anterior urethra cancer Approved [129]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [130]
Quercetin DM3NC4M Obesity 5B81 Approved [131]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [132]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [133]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [134]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [93]
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Drug(s) Affected By Transcription factor Jun (JUN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [135]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [136]
Fructose DM43AN2 Vomiting MD90 Approved [72]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [137]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [138]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [139]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [140]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [141]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [142]
Methotrexate DM2TEOL Anterior urethra cancer Approved [143]
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Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [144]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [145]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [146]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [147]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [138]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [148]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [149]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [151]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [149]
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Drug(s) Affected By C-C motif chemokine 2 (CCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [152]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [153]
Gefitinib DM15F0X Colon adenocarcinoma Approved [154]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [155]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [156]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [157]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [158]
Methotrexate DM2TEOL Anterior urethra cancer Approved [159]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [160]
Quercetin DM3NC4M Obesity 5B81 Approved [161]
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Drug(s) Affected By Calnexin (CANX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [162]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [163]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [164]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [165]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [166]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [167]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [98]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [81]
Motexafin gadolinium DMEJKRF Brain cancer 2A00 Approved [163]
Clozapine DMFC71L Schizophrenia 6A20 Approved [168]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [169]
Triacetin DM0AEPG Onychomycosis EE12.1 Approved [170]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [139]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [171]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [172]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [173]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [174]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [175]
Methotrexate DM2TEOL Anterior urethra cancer Approved [176]
Quercetin DM3NC4M Obesity 5B81 Approved [177]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [178]
Stavudine DM6DEK9 Human immunodeficiency virus infection 1C62 Approved [178]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [179]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [167]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [98]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [180]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [181]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [116]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [182]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [83]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [183]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [137]
Gefitinib DM15F0X Colon adenocarcinoma Approved [184]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [185]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [142]
Quercetin DM3NC4M Obesity 5B81 Approved [186]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [178]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [187]
Vinblastine DM5TVS3 Advanced cancer 2A00-2F9Z Approved [142]
Ethacrynic acid DM60QMR Edema MG29 Approved [188]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [189]
Quercetin DM3NC4M Obesity 5B81 Approved [177]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [190]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [191]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [192]
Nevirapine DM6HX9B Human immunodeficiency virus infection 1C62 Approved [11]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [193]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [167]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [103]
Ethanol DMDRQZU Chronic pain MG30 Approved [194]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [114]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [81]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [83]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [195]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [196]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [197]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [97]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [132]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [198]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [199]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [200]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [201]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [98]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [181]
Levodopa DMN3E57 Parkinson disease 8A00.0 Approved [202]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [203]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [204]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [139]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [172]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [182]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [172]
Quercetin DM3NC4M Obesity 5B81 Approved [205]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [172]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [206]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [207]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [208]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [96]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [78]
Selenium DM25CGV N. A. N. A. Approved [97]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [114]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [81]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [181]
ANGIOTENSIN II DMLWQ27 Increase blood pressure BA04 Approved [209]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [83]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [210]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [211]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Human immunodeficiency virus Reverse transcriptase (HIV RT) TT84ETX POL_HV1B1 Modulator [2]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Multidrug resistance-associated protein 3 (ABCC3) DTQ3ZHF MRP3_HUMAN Substrate [3]
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [4]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) Main DME DE4LYSA CP3A4_HUMAN Substrate [5]
Cytochrome P450 1A2 (CYP1A2) DEJGDUW CP1A2_HUMAN Substrate [6]
Cytochrome P450 2B6 (CYP2B6) DEPKLMQ CP2B6_HUMAN Substrate [7]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Albumin (ALB) OTVMM513 ALBU_HUMAN Protein Interaction/Cellular Processes [8]
Bcl-2-like protein 11 (BCL2L11) OTNQQWFJ B2L11_HUMAN Gene/Protein Processing [9]
Bile salt export pump (ABCB11) OTRU7THO ABCBB_HUMAN Gene/Protein Processing [10]
C-C motif chemokine 2 (CCL2) OTAD2HEL CCL2_HUMAN Protein Interaction/Cellular Processes [11]
Calnexin (CANX) OTYP1F6J CALX_HUMAN Protein Interaction/Cellular Processes [12]
CCAAT/enhancer-binding protein alpha (CEBPA) OTOM9OE4 CEBPA_HUMAN Gene/Protein Processing [11]
Cytochrome P450 2C19 (CYP2C19) OTFMJYYE CP2CJ_HUMAN Gene/Protein Processing [13]
DNA damage-inducible transcript 3 protein (DDIT3) OTI8YKKE DDIT3_HUMAN Gene/Protein Processing [12]
Dynamin-1-like protein (DNM1L) OTXK1Q1G DNM1L_HUMAN Protein Interaction/Cellular Processes [12]
Dynamin-like 120 kDa protein, mitochondrial (OPA1) OTJGNWPW OPA1_HUMAN Gene/Protein Processing [12]

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