Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM15HL8)

Drug Name
Clindamycin Drug Info
Synonyms
Antirobe; CLDM; CLY; Chlolincocin; Chlorlincocin; Chlorodeoxylincomycin; Chlorolincomycin; Cleocin; ClindaDerm; Clindamicina; Clindamycine; Clindamycinum; Clinimycin; Dalacine; Klimicin; Sobelin; Zindaclin; Cleocin HCl; Cleocin T Gel; Cleocin T Lotion; Cleocin T Topical Solution; Clindamycine [French]; Dalacin C; Dalacin C Flavored Granules; Dalacin C Phosphate; Dalacin T Topical Solution; ResiDerm A; Klindan 300; U 21251; Cleocin (TN); Clindacin (TN); Clindamicina [INN-Spanish]; Clindamycin & Interleukin 12; Clindamycin & VRC3375; Clindamycine [INN-French]; Clindamycinum [INN-Latin]; Dalacin (TN); Evoclin (TN); U-21251; CLINDA & IL-12; Clindamycin (USAN/INN); Clindamycin [USAN:BAN:INN]; U-21,251; 7(S)-Chloro-7-deoxylincomycin; 7-CDL; 7-Chloro-7-deoxylincomycin; 7-Chlorolincomycin; 7-Deoxy-7(S)-chlorolincomycin
Indication
Disease Entry ICD 11 Status REF
Acne vulgaris ED80 Approved [1]
Aspiration pneumonia Approved [2]
Bacteremia 1A73 Approved [2]
Bacterial vaginosis MF3A Approved [2]
Pleural empyema Approved [2]
Staphylococcal pneumonia Approved [2]
Staphylococcus aureus infection Approved [2]
Streptococcal pneumonia Approved [2]
Pelvic inflammatory disease GA05 Investigative [2]
Therapeutic Class
Antibiotics
Cross-matching ID
PubChem CID
446598
CAS Number
CAS 18323-44-9
TTD Drug ID
DM15HL8
VARIDT Drug ID
DR00972
INTEDE Drug ID
DR0340
ACDINA Drug ID
D00136

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DME
DOT
Drug Status:
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Bacterial 50S ribosomal RNA (Bact 50S rRNA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [9]
Telithromycin DMZ4P3A Bacterial infection 1A00-1C4Z Approved [10]
Clarithromycin DM4M1SG Acute maxillary sinusitis Approved [3]
Dirithromycin DM0D9YJ Bacterial infection 1A00-1C4Z Approved [11]
Zithromax DMN4H2O Syphilis infection 1A6Z Approved [12]
Troleandomycin DMUZNIG Bacterial infection 1A00-1C4Z Approved [13]
Retapamulin DM9JXB7 Impetigo 1B72 Approved [14]
Dalfopristin DM4LTKV Bacterial infection 1A00-1C4Z Approved [15]
Tedizolid DMG2SKR Skin infection 1F28-1G0Z Approved [16]
Gentamicine sulfate DMBT7MI Bacterial infection 1A00-1C4Z Approved [17]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [18]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [19]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [20]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [21]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [22]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [23]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [24]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [25]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [19]
Verapamil DMA7PEW Angina pectoris BA40 Approved [26]
Eplerenone DMF0NQR Heart failure BD10-BD13 Approved [27]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [28]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [29]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [30]
Proguanil DMBL79I Malaria 1F40-1F45 Approved [31]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [31]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [32]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [33]
Capsaicin DMGMF6V Back pain ME84.Z Approved [34]
Axitinib DMGVH6N Renal cell carcinoma 2C90 Approved [35]
⏷ Show the Full List of 20 Drug(s)
Drug(s) Affected By HLA class II histocompatibility antigen, DRB1 beta chain (HLA-DRB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Gefitinib DM15F0X Colon adenocarcinoma Approved [8]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [8]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [36]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [37]
Cefepime DMHVWIK Bacterial infection 1A00-1C4Z Approved [8]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [38]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [39]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [40]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [41]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [8]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By HLA class I histocompatibility antigen, alpha chain E (HLA-E)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [8]
Selenium DM25CGV N. A. N. A. Approved [42]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [8]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [8]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [43]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [44]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [45]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [8]
Testosterone DM7HUNW Hot flushes GA30 Approved [46]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [47]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Collagenase 3 (MMP13)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [48]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [48]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [49]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [50]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [51]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [52]
Doxycycline DM7ICNU Acne vulgaris ED80 Approved [6]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [53]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [54]
Prinomastat DM9HOKG Lung cancer 2C25.0 Approved [55]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Bacterial 50S ribosomal RNA (Bact 50S rRNA) TTUWYEA NOUNIPROTAC Binder [3]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) Main DME DE4LYSA CP3A4_HUMAN Substrate [4]
Beta-lactamase (blaB) DEMSNER A4LA84_EDWTA Substrate [5]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Collagenase 3 (MMP13) OTY8BZIE MMP13_HUMAN Gene/Protein Processing [6]
Cytochrome P450 3A4 (CYP3A4) OTQGYY83 CP3A4_HUMAN Gene/Protein Processing [7]
HLA class I histocompatibility antigen, alpha chain E (HLA-E) OTX1CTFB HLAE_HUMAN Gene/Protein Processing [8]
HLA class II histocompatibility antigen, DRB1 beta chain (HLA-DRB1) OTRGGIFP DRB1_HUMAN Gene/Protein Processing [8]

References

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2 Clindamycin FDA Label
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