Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMD5JU8)

Drug Name
Cephalexin Drug Info
Synonyms
Adcadina; Ades[prex; Alcephin; Alexin; Alsporin; Ambal; Aristosporin; Azabort; Bactopenor; Beliam; Biocef; CEX; Carnosporin; Cefablan; Cefacet; Cefadal; Cefadin; Cefadina; Cefalekey; Cefaleksin; Cefalessina; Cefalexgobens; Cefalexin; Cefalexina; Cefalexine; Cefalexinum; Cefalin; Cefalival; Cefaloto; Cefaseptin; Cefax; Ceffanex; Cefibacter; Ceflax; Ceforal; Cefovit; Celexin; Cepastar; Cepexin; Cephacillin; Cephalexine; Cephalexinum; Cephalobene; Cephanasten; Cephaxin; Cephin; Cepol; Ceporex; Ceporexin; Ceporexine; Check; Cophalexin; Domucef; Doriman; Durantel; Efemida; Erocetin; Factagard; Felexin; Fexin; Ibilex; Ibrexin; Inphalex; Karilexina; Kefalospes; Keflet; Keflex; Kefolan; Keforal; Keftab; Kekrinal; Kidolex; Lafarine; Larixin; Lenocef; Lexibiotico; Loisine; Lonflex; Lopilexin; Losporal; Madlexin; Maksipor; Mamalexin; Mamlexin; Medolexin; Medoxine; Neokef; Neolexina; Noveol; Novolexin; Nufex; Oracef; Oriphex; Oroxin; Ortisporina; Ospexin; Palitrex; Pectril; Prindex; Pyassan; Rilexine; Roceph; Rogevil; Sanaxin; Sartosona; Sencephalin; Sepexin; Servicef; Servispor; Sialexin; Sinthecillin; Sintolexyn; Sporicef; Sporidex; Syncl; Syncle; Synecl; Tepaxin; Theratrex; Tokiolexin; Uphalexin; Viosporine; Voxxim; Winlex; Zabytrex; Zozarine; Cefalessina [DCIT]; Cefalexin Scand Pharm; Cefalexin Sodium; Cefalexin generics; Cefalexin hydrate; Cefalexin monohydrate; Cefalexina Northia; Cefalexina Richet; Cephalex von ct; Cephalexin hydrate; Cephalexin monohydrate; Ceporex Forte; Durantel DS; Henina Oral; Panixine Disperdose; Roceph Distab; Lilly 66873; S 6437; SQ 20248; Cefa-iskia; Cefalexin (JP15); Cefalexin.H2O; Cefalexina [INN-Spanish]; Cefalexine [INN-French]; Cefalexinum [INN-Latin]; Cephalexin(USP); Cephalexin (anhydrous); Cephalexin 1-hydrate; Cephalexin 1-wasser; Cephalexin [USAN:BAN]; Cephalexin.H2O; Ceporexin-E; Cusisporina-Cefalox; Ed A-Ceph; KS-1134; Keflex (TN); Keftab (TN); L-Keflex; Panixine disperdose (TN); Sporidex (TN); Cephalexin, (6R-(6alpha,7beta))-Isomer; 7-(D-2-Amino-2-phenylacetamido)-3-methyl-delta (sup 3)-cephem-4-carboxylic acid; 7-(D-2-Amino-2-phenylacetamido)-3-methyl-delta3-cephem-4-carboxylic acid; 7-(D-alpha-Aminophenylacetamido)desacetoxycephalosporanic acid
Indication
Disease Entry ICD 11 Status REF
Acute otitis media AB00 Approved [1]
Bacterial infection 1A00-1C4Z Approved [2]
Prostatitis Approved [1]
Staphylococcus aureus infection Approved [1]
Therapeutic Class
Antibiotics
Cross-matching ID
PubChem CID
27447
ChEBI ID
CHEBI:3534
CAS Number
CAS 15686-71-2
TTD Drug ID
DMD5JU8
VARIDT Drug ID
DR00330
INTEDE Drug ID
DR0284
ACDINA Drug ID
D00114

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Bacterial Penicillin binding protein (Bact PBP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ampicillin DMHWE7P Acute epiglottitis Approved [11]
Cefazolin DMPDYFR Bacteremia 1A73 Approved [12]
Ceftriaxone DMCEW64 Acute gonococcal cervicitis Approved [13]
Ticarcillin DM4ME02 Aspiration pneumonia Approved [14]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [15]
Meropenem DM62UHC Bacterial infection 1A00-1C4Z Approved [13]
Cefadroxil DMMC345 Bacterial infection 1A00-1C4Z Approved [16]
Clofarabine DMCVJ86 Acute lymphoblastic leukaemia 2A85 Approved [17]
Carbenicillin DMLEDNK Infection of the upper and lower urinary tract GC08 Approved [18]
Piperacillin DMTBKF3 Acute gonococcal cervicitis Approved [19]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Transported By Multidrug and toxin extrusion protein 1 (SLC47A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aciclovir DMYLOVR Genital herpes 1A94 Approved [20]
Metformin DM89QE1 Colorectal carcinoma Approved [21]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [20]
Cimetidine DMH61ZB Acid-reflux disorder DA22 Approved [20]
Chloroquine DMSI5CB Malaria 1F40-1F45 Approved [22]
Procainamide DMNMXR8 Ventricular arrhythmias BC71 Approved [20]
Topotecan DMP6G8T Central nervous system neoplasm Approved [20]
LY2835219 DM93VBZ Breast cancer 2C60-2C65 Approved [23]
Dofetilide DMPN1TW Sinus rhythm disorder BC9Y Approved [24]
Pyrimethamine DM5X7VY Malaria 1F40-1F45 Approved [25]
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Drug(s) Transported By Peptide transporter 1 (SLC15A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [26]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [27]
Ampicillin DMHWE7P Acute epiglottitis Approved [28]
Losartan DM72JXH Diabetic kidney disease GB61.Z Approved [29]
Enalapril DMNFUZR Congestive heart failure BD10 Approved [30]
Cefazolin DMPDYFR Bacteremia 1A73 Approved [31]
Ceftriaxone DMCEW64 Acute gonococcal cervicitis Approved [32]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [27]
Cefadroxil DMMC345 Bacterial infection 1A00-1C4Z Approved [29]
Irbesartan DMTP1DC Diabetic kidney disease GB61.Z Approved [29]
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Drug(s) Transported By Peptide transporter 2 (SLC15A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [26]
Ampicillin DMHWE7P Acute epiglottitis Approved [4]
Enalapril DMNFUZR Congestive heart failure BD10 Approved [33]
Entecavir DM7VTQO Hepatitis B virus infection 1E51.0 Approved [34]
Cefadroxil DMMC345 Bacterial infection 1A00-1C4Z Approved [35]
Valaciclovir DMHKS94 Genital herpes 1A94 Approved [36]
Cefaclor DMJXDGC Bacterial infection 1A00-1C4Z Approved [26]
Aminolevulinic acid hci DMS4BLQ Acne vulgaris ED80 Approved [37]
Spirapril DM5XLTY Hypertension BA00-BA04 Approved [38]
Cefixime DMY60I8 Acute gonococcal cervicitis Approved [4]
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Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [39]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [40]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [41]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [42]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [43]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [44]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [45]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [46]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [40]
Verapamil DMA7PEW Angina pectoris BA40 Approved [47]
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Drug(s) Metabolized By Cytochrome P450 2D6 (CYP2D6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [48]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [49]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [50]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [43]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [47]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [51]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [52]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [53]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [54]
Propranolol DM79NTF Angina pectoris BA40 Approved [55]
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Drug(s) Metabolized By N-acylhomoserine lactone acylase (lacA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [9]
Ampicillin DMHWE7P Acute epiglottitis Approved [9]
Cefadroxil DMMC345 Bacterial infection 1A00-1C4Z Approved [9]
Carbenicillin DMLEDNK Infection of the upper and lower urinary tract GC08 Approved [9]
Benzylpenicillin DMS9503 Actinomycosis Phase 3 [9]
Drug(s) Affected By HLA class II histocompatibility antigen, DP alpha 1 chain (HLA-DPA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [56]
Fluoxetine DM3PD2C Bipolar depression Approved [10]
Cinoxacin DM4EWNS Urinary tract infection GC08 Approved [10]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [57]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [58]
Testosterone DM7HUNW Hot flushes GA30 Approved [59]
Valdecoxib DMAY7H4 Osteoarthritis FA00-FA05 Approved [10]
Testosterone enanthate DMB6871 N. A. N. A. Approved [60]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [61]
Aztreonam DMDNJHG Bacterial infection 1A00-1C4Z Approved [10]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Bacterial Penicillin binding protein (Bact PBP) TTJP4SM NOUNIPROTAC Binder [3]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Peptide transporter 2 (SLC15A2) DT8QKNP S15A2_HUMAN Substrate [4]
Peptide transporter 1 (SLC15A1) DT9G7XN S15A1_HUMAN Substrate [5]
Multidrug and toxin extrusion protein 1 (SLC47A1) DTZGT0P S47A1_HUMAN Substrate [6]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Substrate [7]
Cytochrome P450 2D6 (CYP2D6) DECB0K3 CP2D6_HUMAN Substrate [8]
N-acylhomoserine lactone acylase (lacA) DEIU0XN A0A0A1VBK6_9BURK Substrate [9]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
HLA class II histocompatibility antigen, DP alpha 1 chain (HLA-DPA1) OT7OG7Y2 DPA1_HUMAN Gene/Protein Processing [10]

References

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