General Information of Drug (ID: DMXBQAM)

Drug Name
Miglitol Drug Info
Synonyms Diastabol; Glyset; Plumarol; Seibule; Glyset (TN); SK-983; Bay-m-1099; Miglitol (JAN/USAN/INN); (2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
Indication
Disease Entry ICD 11 Status REF
Diabetic complication 5A2Y Approved [1]
Therapeutic Class
Hypoglycemic Agents
Cross-matching ID
PubChem CID
441314
ChEBI ID
CHEBI:6935
CAS Number
CAS 72432-03-2
TTD Drug ID
DMXBQAM
ACDINA Drug ID
D00433

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Voglibose DMUBP9O Diabetic complication 5A2Y Approved [4]
Acarbose DMRM3AW Diabetic complication 5A2Y Approved [5]
Rh-alphaglucosidase DMNF0G8 Pompe disease 5C51.3 Approved [6]
Deoxynojirimycin DM2ATZB Pompe disease 5C51.3 Phase 3 [7]
Alpha-glucosidase DM2RTGP Muscle disease FB3Z Phase 3 [8]
PAZ-320 DMU0812 Type-2 diabetes 5A11 Phase 2 [9]
SC-49483 DM180VX Acquired immune deficiency syndrome 1C62.3 Phase 2 [10]
Maltose DMH0ROP N. A. N. A. Phase 1/2 [11]
SALACINOL DMVKQT8 N. A. N. A. Phase 1/2 [12]
Celgosivir DMD1V7I Dengue fever 1D2Z Phase 1/2 [13]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor necrosis factor (TNF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [14]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [15]
Fructose DM43AN2 Vomiting MD90 Approved [16]
Ketoprofen DMRKXPT Bursitis Approved [16]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [17]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [18]
Baclofen DM0QV1J Multiple sclerosis 8A40 Approved [19]
Gefitinib DM15F0X Colon adenocarcinoma Approved [20]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [21]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [22]
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Drug(s) Affected By Interleukin-1 beta (IL1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [23]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [24]
Gefitinib DM15F0X Colon adenocarcinoma Approved [25]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [26]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [27]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [26]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [28]
Selenium DM25CGV N. A. N. A. Approved [29]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [30]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [31]
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Drug(s) Affected By Interleukin-6 (IL6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [32]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [33]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [34]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [35]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [36]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [24]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [22]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [28]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [37]
Methotrexate DM2TEOL Anterior urethra cancer Approved [32]
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Drug(s) Affected By Protein S100-A9 (S100A9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [38]
Methotrexate DM2TEOL Anterior urethra cancer Approved [39]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [40]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [41]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [41]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [42]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [43]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [44]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [45]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [46]
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Drug(s) Affected By Protein S100-A6 (S100A6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [47]
Selenium DM25CGV N. A. N. A. Approved [48]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [40]
Quercetin DM3NC4M Obesity 5B81 Approved [49]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [43]
Panobinostat DM58WKG Chronic graft versus host disease Approved [50]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [51]
Adenosine triphosphate DM79F6G Malnutrition 5B50-5B71 Approved [52]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [53]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [54]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein S100-A4 (S100A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [55]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [56]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [57]
Panobinostat DM58WKG Chronic graft versus host disease Approved [50]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [58]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [59]
Adenosine triphosphate DM79F6G Malnutrition 5B50-5B71 Approved [52]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [60]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [53]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [61]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein S100-A11 (S100A11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [48]
Methotrexate DM2TEOL Anterior urethra cancer Approved [39]
Quercetin DM3NC4M Obesity 5B81 Approved [49]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [56]
Panobinostat DM58WKG Chronic graft versus host disease Approved [50]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [62]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [63]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [44]
Adenosine triphosphate DM79F6G Malnutrition 5B50-5B71 Approved [52]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [46]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein S100-A10 (S100A10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [64]
Panobinostat DM58WKG Chronic graft versus host disease Approved [50]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [65]
Adenosine triphosphate DM79F6G Malnutrition 5B50-5B71 Approved [52]
Testosterone DM7HUNW Hot flushes GA30 Approved [66]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [66]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [53]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [54]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [67]
Folic Acid DMEMBJC Colorectal carcinoma Approved [68]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein S100-A12 (S100A12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [69]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [64]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [43]
Arsenic DMTL2Y1 N. A. N. A. Approved [70]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [71]
Arecoline DMFJZK3 Parkinson disease 8A00.0 Phase 1 [72]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [73]
Milchsaure DM462BT Pruritus EC90 Investigative [74]
D-glucose DMMG2TO Discovery agent N.A. Investigative [75]
⏷ Show the Full List of 9 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Intestinal maltase-glucoamylase (MGAM) TTXWASR MGA_HUMAN Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Interleukin-1 beta (IL1B) OT0DWXXB IL1B_HUMAN Gene/Protein Processing [3]
Interleukin-6 (IL6) OTUOSCCU IL6_HUMAN Protein Interaction/Cellular Processes [3]
Protein S100-A10 (S100A10) OTI71243 S10AA_HUMAN Gene/Protein Processing [3]
Protein S100-A11 (S100A11) OTI57KDN S10AB_HUMAN Gene/Protein Processing [3]
Protein S100-A12 (S100A12) OTF9IIXW S10AC_HUMAN Gene/Protein Processing [3]
Protein S100-A4 (S100A4) OTLRGFSQ S10A4_HUMAN Gene/Protein Processing [3]
Protein S100-A6 (S100A6) OTHHPZQ8 S10A6_HUMAN Gene/Protein Processing [3]
Protein S100-A9 (S100A9) OTOARHCS S10A9_HUMAN Gene/Protein Processing [3]
Tumor necrosis factor (TNF) OT4IE164 TNFA_HUMAN Gene/Protein Processing [3]

References

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74 Transcriptional profiling of lactic acid treated reconstructed human epidermis reveals pathways underlying stinging and itch. Toxicol In Vitro. 2019 Jun;57:164-173.
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