Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMPFN6Y)

Drug Name
Olanzapine Drug Info
Synonyms
Lanzac; Midax; Olansek; Olanzapina; Olanzapinum; Symbyax; Zalasta; Zydis; Zyprexa; Eli Lilly brand of olanzapine; Lilly brand of olanzapine; Zyprexa Intramuscular; Zyprexa Velotab; Zyprexa Zydis; LY 170053; ALKS-7921; KS-1090; LY-170052; LY-170053; Olanzapine (OLA); Olanzapine [USAN:INN]; Olzapin (TN); Rexapin (TN); Zalasta (TN); Zolafren (TN); Zydis (TN); Zyprexa (TN); Olanzapine (JAN/USAN/INN); 2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno(2,3-b)(1,5)benzodiazepine; 2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine; 2-methyl-4-(4-methyl-1-piperazinyl)-10 H-thieno[2,3-b ] [1,5]benzodiazepine; 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine; 2-methyl-4-(4-methylpiperazin-1-yl)-5H-thieno[2,3-b][1,5]benzodiazepine; 2-methyl-4-(4-methylpiperazin-1-yl)-5H-thieno[3,2-c][1,5]benzodiazepine
Indication
Disease Entry ICD 11 Status REF
Bipolar depression Approved [1]
Major depressive disorder 6A70.3 Approved [1]
Schizoaffective disorder 6A21 Approved [1]
Schizophrenia 6A20 Approved [2]
Therapeutic Class
Antipsychotic Agents
Cross-matching ID
PubChem CID
135398745
ChEBI ID
CHEMBL715
CAS Number
CAS 132539-06-1
TTD Drug ID
DMPFN6Y
VARIDT Drug ID
DR00462
INTEDE Drug ID
DR1186
ACDINA Drug ID
D00484

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Patented Agent(s)
Discontinued Drug(s)
Preclinical Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Dopamine D2 receptor (D2R)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [12]
Haloperidol DM96SE0 Delirium Approved [13]
Perphenazine DMA4MRX Schizophrenia 6A20 Approved [14]
Perazine DM2AOTZ Psychotic disorder 6A20-6A25 Approved [15]
Domperidone DMBDPY0 Gastrointestinal disease DE2Z Approved [16]
Levodopa DMN3E57 Parkinson disease 8A00.0 Approved [17]
Quetiapine DM1N62C Anorexia nervosa cachexia 6B80 Approved [18]
Pimozide DMW83TP Schizophrenia 6A20 Approved [19]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [20]
Iloperidone DM6AUFY Schizophrenia 6A20 Approved [21]
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Drug(s) Transported By P-glycoprotein 1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [22]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [23]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Folic Acid DMEMBJC Colorectal carcinoma Approved [25]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [24]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [24]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [26]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [24]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [27]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [28]
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Drug(s) Metabolized By Cytochrome P450 1A2 (CYP1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [29]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [30]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [31]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [32]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [33]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [34]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [35]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [36]
Verapamil DMA7PEW Angina pectoris BA40 Approved [37]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [38]
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Drug(s) Metabolized By Cytochrome P450 2D6 (CYP2D6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [39]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [40]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [41]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [42]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [43]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [44]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [45]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [46]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [47]
Propranolol DM79NTF Angina pectoris BA40 Approved [48]
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Drug(s) Affected By ATP-dependent translocase ABCB1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [49]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [50]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [51]
Lamotrigine DM8SXYG Bipolar disorder 6A60 Approved [52]
Cepharanthine DM9Y5JB N. A. N. A. Approved [53]
Itraconazole DMCR1MV Aspergillosis 1F20 Approved [54]
Clozapine DMFC71L Schizophrenia 6A20 Approved [55]
Midostaurin DMI6E0R Acute myeloid leukaemia 2A60 Approved [56]
Trifluoperazine DMKBYWI Anxiety Approved [57]
Levetiracetam DMTGDN8 Epilepsy 8A60-8A68 Approved [52]
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Drug(s) Affected By D(2) dopamine receptor (DRD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Droperidol DM0DXA8 Nausea MD90 Approved [58]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [58]
Zuclopenthixol DMKYD5N Schizophrenia 6A20 Approved [58]
Meglitinides DM1OFHN Type-2 diabetes 5A11 Approved [59]
Sulpiride DMF54ZG Schizophrenia 6A20 Approved [60]
Risperidone DMN6DXL Bipolar I disorder Approved [61]
Methamphetamine DMPM4SK Anxiety Approved [62]
Bromocriptine DMVE3TK Acromegaly 5A60.0 Approved [63]
Fluphenazine DMIT8LX Psychotic disorder 6A20-6A25 Approved [64]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [65]
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Drug(s) Affected By Lathosterol oxidase (SC5D)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [66]
Fluoxetine DM3PD2C Bipolar depression Approved [67]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [68]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [69]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [70]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [71]
Testosterone DM7HUNW Hot flushes GA30 Approved [72]
Haloperidol DM96SE0 Delirium Approved [71]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [73]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [74]
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Drug(s) Affected By Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMGCS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [75]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [76]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [66]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [77]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [77]
Quercetin DM3NC4M Obesity 5B81 Approved [78]
Fluoxetine DM3PD2C Bipolar depression Approved [77]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [68]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [79]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [80]
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Drug(s) Affected By Long-chain fatty acid transport protein 2 (SLC27A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [81]
Methotrexate DM2TEOL Anterior urethra cancer Approved [82]
Quercetin DM3NC4M Obesity 5B81 Approved [83]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [84]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [85]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [70]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [86]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [87]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [88]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [89]
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Drug(s) Affected By Bile salt export pump (ABCB11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [90]
Ezetimibe DM7A8TW Atherosclerosis BD40 Approved [91]
Glipizide DMZA5PQ Diabetic complication 5A2Y Approved [91]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [92]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [90]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [91]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [93]
Gefitinib DM15F0X Colon adenocarcinoma Approved [90]
Drospirenone DM1A9W3 Acne vulgaris ED80 Approved [94]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [90]
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Drug(s) Affected By Ceruloplasmin (CP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [95]
Quercetin DM3NC4M Obesity 5B81 Approved [83]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [96]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [97]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [98]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [89]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [73]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [99]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [100]
Ampicillin DMHWE7P Acute epiglottitis Approved [83]
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Drug(s) Affected By Prothrombin (F2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [101]
Methotrexate DM2TEOL Anterior urethra cancer Approved [82]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [102]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [103]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [104]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [105]
Phytonadione DM8HDOL Bleeding disorder GA20-GA21 Approved [106]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [73]
Testosterone enanthate DMB6871 N. A. N. A. Approved [107]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [108]
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Drug(s) Affected By Alpha-1-antichymotrypsin (SERPINA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [109]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [110]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [111]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [109]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [109]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [112]
Fluoxetine DM3PD2C Bipolar depression Approved [109]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [113]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [113]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [109]
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Drug(s) Affected By Alpha-2-macroglobulin (A2M)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [114]
Prednisone DM2HG4X Acute asthma CA23 Approved [115]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [68]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [116]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [70]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [116]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [117]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [73]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [118]
Aminocaproic Acid DMFGND4 Bleeding disorder GA20-GA21 Approved [115]
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Drug(s) Affected By Collagen alpha-1(I) chain (COL1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [58]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [119]
Diazepam DM08E9O Alcohol withdrawal Approved [120]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [121]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [122]
Methotrexate DM2TEOL Anterior urethra cancer Approved [123]
Ceruletide DM2WE5K Caerulein stimulated gastric and pancreatic secretion 5A4Y Approved [124]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [125]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [126]
Quercetin DM3NC4M Obesity 5B81 Approved [127]
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Drug(s) Affected By Complement component C9 (C9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [76]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [128]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [118]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [92]
Arsenic DMTL2Y1 N. A. N. A. Approved [129]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [130]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [131]
3R14S-OCHRATOXIN A DM2KEW6 Discovery agent N.A. Investigative [132]
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Drug(s) Affected By Albumin (ALB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [133]
Sulfamethoxazole DMB08GE Acute otitis media AB00 Approved [58]
Tolbutamide DM02AWV Advanced cancer 2A00-2F9Z Approved [134]
Diazepam DM08E9O Alcohol withdrawal Approved [135]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [136]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [137]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [138]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [101]
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
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Drug(s) Affected By Vitamin D-binding protein (GC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [117]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [73]
Ethanol DMDRQZU Chronic pain MG30 Approved [142]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [143]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [144]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [145]
Cholecalciferol DMGU74E Adult acute monocytic leukemia Approved [146]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [147]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [148]
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Drug(s) Affected By Hemopexin (HPX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [79]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [73]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [118]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [149]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [150]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [151]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [144]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [152]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [153]
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Drug(s) Affected By Histidine-rich glycoprotein (HRG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [79]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [154]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [117]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [73]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [118]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [155]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [156]
Arsenic DMTL2Y1 N. A. N. A. Approved [157]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [144]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [73]
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Drug(s) Affected By Alpha-1B-glycoprotein (A1BG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [83]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [84]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [158]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [118]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [159]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [149]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [160]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [161]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [162]
acetaldehyde DMJFKG4 Discovery agent N.A. Investigative [163]
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Drug(s) Affected By Sex hormone-binding globulin (SHBG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Levonorgestrel DM1DP7T Atypical endometrial hyperplasia Approved [164]
Quercetin DM3NC4M Obesity 5B81 Approved [83]
Fructose DM43AN2 Vomiting MD90 Approved [165]
Oxcarbazepine DM5PU6O Epilepsy 8A60-8A68 Approved [166]
Estrone DM5T6US Acne vulgaris ED80 Approved [167]
Testosterone DM7HUNW Hot flushes GA30 Approved [168]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [158]
Dienestrol DMBSXI0 Atrophic vaginitis GA30.2 Approved [167]
Hesperetin DMKER83 High blood cholesterol level 5C80.00 Approved [167]
Masoprocol DMMVNZ0 Prostate cancer 2C82.0 Approved [167]
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Drug(s) Affected By Plasma protease C1 inhibitor (SERPING1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [96]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [70]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [169]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [73]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [74]
Danazol DML8KTN Menorrhagia GA20.50 Approved [170]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [149]
Arsenic DMTL2Y1 N. A. N. A. Approved [129]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [171]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [172]
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Drug(s) Affected By Complement C4-A (C4A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [173]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [100]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [144]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [174]
Diphenylpyraline DMW4X37 Allergic rhinitis CA08.0 Approved [175]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [148]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [176]
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Drug(s) Affected By Complement component C6 (C6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [73]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [118]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [144]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [174]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [131]
Drug(s) Affected By Solute carrier family 2, facilitated glucose transporter member 4 (SLC2A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [177]
Fructose DM43AN2 Vomiting MD90 Approved [178]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [179]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [180]
Testosterone DM7HUNW Hot flushes GA30 Approved [181]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [181]
Haloperidol DM96SE0 Delirium Approved [182]
Leflunomide DMR8ONJ Arthritis FA20 Approved [183]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [184]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [185]
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Drug(s) Affected By Inter-alpha-trypsin inhibitor heavy chain H2 (ITIH2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [73]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [118]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [186]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [149]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [144]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [187]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [147]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [131]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [188]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [189]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 5-hydroxytryptamine receptor 2A (HTR2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [58]
Fluphenazine DMIT8LX Psychotic disorder 6A20-6A25 Approved [64]
Paliperidone DM7NPJS Psychotic disorder 6A20-6A25 Approved [190]
Haloperidol DM96SE0 Delirium Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [118]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [191]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [192]
Arsenic DMTL2Y1 N. A. N. A. Approved [193]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [172]
Ketanserin DMVLMW6 Hypertension BA00-BA04 Approved [194]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Catenin beta-1 (CTNNB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [195]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [196]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [197]
Quercetin DM3NC4M Obesity 5B81 Approved [198]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [199]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [200]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [201]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [202]
Testosterone DM7HUNW Hot flushes GA30 Approved [203]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [204]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pituitary adenylate cyclase-activating polypeptide type I receptor (ADCYAP1R1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [205]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [169]
Haloperidol DM96SE0 Delirium Approved [206]
Exemestane DM9HPW3 Hormonally-responsive breast cancer 2C60-2C65 Approved [207]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [118]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [205]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [207]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [205]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [208]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [76]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Afamin (AFM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [73]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [118]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [79]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [144]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [73]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [209]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By 5-hydroxytryptamine receptor 6 (HTR6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clozapine DMFC71L Schizophrenia 6A20 Approved [8]
Methamphetamine DMPM4SK Anxiety Approved [210]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [131]
LYSERGIC ACID DIETHYLAMIDE DMACMLO Addictive disorder 6C50-6C5Z Withdrawn from market [211]
SB 258585 DM2QJKZ Discovery agent N.A. Investigative [212]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [213]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Bcl-2-interacting killer (BIK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [214]
Methotrexate DM2TEOL Anterior urethra cancer Approved [215]
Quercetin DM3NC4M Obesity 5B81 Approved [83]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [216]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [217]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [218]
Leflunomide DMR8ONJ Arthritis FA20 Approved [183]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [158]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [74]
Clozapine DMFC71L Schizophrenia 6A20 Approved [219]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Inter-alpha-trypsin inhibitor heavy chain H4 (ITIH4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [73]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [118]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [150]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [144]
Testosterone undecanoate DMZO10Y Hypogonadism 5A61.0 Approved [220]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [131]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Long-chain fatty acid transport protein 5 (SLC27A5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [68]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [69]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [86]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [73]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [118]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [221]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [149]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [144]
Berberine DMC5Q8X N. A. N. A. Phase 4 [222]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [73]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By D(3) dopamine receptor (DRD3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Haloperidol DM96SE0 Delirium Approved [223]
Clozapine DMFC71L Schizophrenia 6A20 Approved [224]
Risperidone DMN6DXL Bipolar I disorder Approved [225]
Folic Acid DMEMBJC Colorectal carcinoma Approved [226]
Methamphetamine DMPM4SK Anxiety Approved [227]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [228]
Droperidol DM0DXA8 Nausea MD90 Approved [58]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [58]
Fluphenazine DMIT8LX Psychotic disorder 6A20-6A25 Approved [58]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [58]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 5-hydroxytryptamine receptor 1A (HTR1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Trazodone DMK1GBJ Depression 6A70-6A7Z Approved [229]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [229]
Fluoxetine DM3PD2C Bipolar depression Approved [230]
Methamphetamine DMPM4SK Anxiety Approved [231]
Perospirone DMVHJLX Psychotic disorder 6A20-6A25 Approved [7]
Etoperidone DMR7U8F N. A. N. A. Phase 4 [229]
phorbol 12-myristate 13-acetate DMJWD62 Acute myeloid leukaemia 2A60 Phase 2 [232]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [131]
DU 125530 DM63UA9 Mood disorder 6A60-6E23 Discontinued in Phase 2 [233]
THAPSIGARGIN DMDMQIE N. A. N. A. Preclinical [232]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 5-hydroxytryptamine receptor 2C (HTR2C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [234]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [234]
Fluoxetine DM3PD2C Bipolar depression Approved [234]
Fluphenazine DMIT8LX Psychotic disorder 6A20-6A25 Approved [64]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [96]
Nortriptyline DM4KDYJ Depression 6A70-6A7Z Approved [235]
Testosterone DM7HUNW Hot flushes GA30 Approved [181]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [236]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [73]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [74]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Aquaporin-4 (AQP4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [237]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [238]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [239]
Guanfacine extended release DMB1CZ8 Attention deficit hyperactivity disorder 6A05.Z Approved [237]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [118]
Ammonia DMOEVK6 Coronary artery disease BA80 Approved [240]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [148]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [241]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By D(4) dopamine receptor (DRD4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clozapine DMFC71L Schizophrenia 6A20 Approved [242]
Haloperidol DM96SE0 Delirium Approved [243]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [118]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [159]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [191]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [150]
Methamphetamine DMPM4SK Anxiety Approved [244]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [245]
Droperidol DM0DXA8 Nausea MD90 Approved [58]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [58]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Dopamine D2 receptor (D2R) TTEX248 DRD2_HUMAN Agonist [3]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [4]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 2D6 (CYP2D6) Main DME DECB0K3 CP2D6_HUMAN Substrate [5]
Cytochrome P450 1A2 (CYP1A2) Main DME DEJGDUW CP1A2_HUMAN Substrate [6]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
5-hydroxytryptamine receptor 1A (HTR1A) OT38K9MK 5HT1A_HUMAN Drug Response [7]
5-hydroxytryptamine receptor 2A (HTR2A) OTWXJX0M 5HT2A_HUMAN Protein Interaction/Cellular Processes [8]
5-hydroxytryptamine receptor 2C (HTR2C) OT6H8DE0 5HT2C_HUMAN Drug Response [9]
5-hydroxytryptamine receptor 6 (HTR6) OT8GTDDY 5HT6R_HUMAN Protein Interaction/Cellular Processes [8]
Afamin (AFM) OTPOR8IO AFAM_HUMAN Post-Translational Modifications [10]
Albumin (ALB) OTVMM513 ALBU_HUMAN Post-Translational Modifications [10]
Alpha-1-antichymotrypsin (SERPINA3) OT9BP2S0 AACT_HUMAN Post-Translational Modifications [10]
Alpha-1B-glycoprotein (A1BG) OTFVUGNQ A1BG_HUMAN Post-Translational Modifications [10]
Alpha-2-macroglobulin (A2M) OTFTX90K A2MG_HUMAN Post-Translational Modifications [10]
Aquaporin-4 (AQP4) OTA9MYD5 AQP4_HUMAN Drug Response [11]

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