Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMDI6R4)

Drug Name
Dabigatran Drug Info
Synonyms Pradaxa (TN)
Indication
Disease Entry ICD 11 Status REF
Stroke 8B20 Approved [1]
Cross-matching ID
PubChem CID
216210
ChEBI ID
CHEBI:70752
CAS Number
CAS 211914-51-1
TTD Drug ID
DMDI6R4
VARIDT Drug ID
DR00241

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Coagulation factor IIa (F2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Argatroban DMFI46A Thrombosis DB61-GB90 Approved [5]
Pyridoxal Phosphate DMO2K0J Malnutrition 5B50-5B71 Approved [6]
Bivalirudin DMECRX1 Thrombocytopenia 3B64 Approved [7]
Ximelegatran DMU8ANS Myocardial infarction BA41-BA43 Approved [8]
Desirudin Recombinant DM2BTFN Coagulation defect 3B10.0 Approved [9]
Human prothrombin complex concentrate DMPHVQ1 Bleeding disorder GA20-GA21 Approved [10]
Lepirudin DM1I3D5 Thrombocytopenia 3B64 Approved [11]
Anisindione DM2C48U Coagulation defect 3B10.0 Approved [12]
ATryn antithrombin DM79Y2T Multiple sclerosis 8A40 Approved [13]
Hirudin DMYOC29 N. A. N. A. Phase 4 [14]
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Drug(s) Transported By P-glycoprotein 1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [15]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [16]
Methotrexate DM2TEOL Anterior urethra cancer Approved [17]
Folic Acid DMEMBJC Colorectal carcinoma Approved [18]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [17]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [17]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [19]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [17]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [20]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [21]
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Drug(s) Affected By Retinal dehydrogenase 2 (ALDH1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [4]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [4]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [4]
Panobinostat DM58WKG Chronic graft versus host disease Approved [22]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [4]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [4]
Ramelteon DM7IW9J Insomnia 7A00-7A0Z Approved [4]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [23]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [24]
Metoclopramide DMFA5MY Nausea MD90 Approved [4]
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Drug(s) Affected By Homeobox protein Hox-B9 (HOXB9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [25]
Methotrexate DM2TEOL Anterior urethra cancer Approved [26]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [27]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [28]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [4]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [4]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [29]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [24]
Abacavir DMMN36E Human immunodeficiency virus infection 1C62 Approved [4]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [4]
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Drug(s) Affected By Paired box protein Pax-3 (PAX3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [30]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [4]
Panobinostat DM58WKG Chronic graft versus host disease Approved [22]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [4]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [4]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [31]
Folic Acid DMEMBJC Colorectal carcinoma Approved [32]
Abacavir DMMN36E Human immunodeficiency virus infection 1C62 Approved [4]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [33]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [34]
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Drug(s) Affected By Paired box protein Pax-6 (PAX6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [35]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [4]
Panobinostat DM58WKG Chronic graft versus host disease Approved [22]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [4]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [36]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [4]
Ramelteon DM7IW9J Insomnia 7A00-7A0Z Approved [4]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [29]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [37]
Folic Acid DMEMBJC Colorectal carcinoma Approved [33]
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Drug(s) Affected By Homeobox protein MOX-1 (MEOX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [38]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [4]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [4]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [4]
Panobinostat DM58WKG Chronic graft versus host disease Approved [22]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [39]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [4]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [40]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [4]
Ramelteon DM7IW9J Insomnia 7A00-7A0Z Approved [4]
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Drug(s) Affected By Fibroblast growth factor 8 (FGF8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [41]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [35]
Panobinostat DM58WKG Chronic graft versus host disease Approved [22]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [4]
Ramelteon DM7IW9J Insomnia 7A00-7A0Z Approved [4]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [24]
Dolutegravir DMCZGRE Human immunodeficiency virus infection 1C62 Approved [42]
Folic Acid DMEMBJC Colorectal carcinoma Approved [32]
Abacavir DMMN36E Human immunodeficiency virus infection 1C62 Approved [4]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [4]
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Drug(s) Affected By Transcription factor 15 (TCF15)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [4]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [4]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [4]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [4]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [4]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [4]
Abacavir DMMN36E Human immunodeficiency virus infection 1C62 Approved [4]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [4]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [4]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [43]
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Drug(s) Affected By Oligodendrocyte transcription factor 3 (OLIG3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [4]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [4]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [4]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [4]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [4]
Ramelteon DM7IW9J Insomnia 7A00-7A0Z Approved [4]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [33]
Ethanol DMDRQZU Chronic pain MG30 Approved [44]
Abacavir DMMN36E Human immunodeficiency virus infection 1C62 Approved [4]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [4]
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Drug(s) Affected By Eyes absent homolog 1 (EYA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [45]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [4]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [4]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [4]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [4]
Ramelteon DM7IW9J Insomnia 7A00-7A0Z Approved [4]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [4]
Abacavir DMMN36E Human immunodeficiency virus infection 1C62 Approved [4]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [4]
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Drug(s) Affected By Forkhead box protein C2 (FOXC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [47]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [4]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [4]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [4]
Panobinostat DM58WKG Chronic graft versus host disease Approved [22]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [4]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [4]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [4]
Abacavir DMMN36E Human immunodeficiency virus infection 1C62 Approved [4]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [4]
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Drug(s) Affected By Neurogenin-2 (NEUROG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [4]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [4]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [4]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [4]
Leflunomide DMR8ONJ Arthritis FA20 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [24]
Folic Acid DMEMBJC Colorectal carcinoma Approved [33]
Abacavir DMMN36E Human immunodeficiency virus infection 1C62 Approved [4]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Coagulation factor IIa (F2) TT6L509 THRB_HUMAN Inhibitor [2]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Eyes absent homolog 1 (EYA1) OTHU807A EYA1_HUMAN Gene/Protein Processing [4]
Fibroblast growth factor 8 (FGF8) OTFU0IUW FGF8_HUMAN Gene/Protein Processing [4]
Forkhead box protein C2 (FOXC2) OT83P1E0 FOXC2_HUMAN Gene/Protein Processing [4]
Homeobox protein Hox-B9 (HOXB9) OTMVHQOU HXB9_HUMAN Gene/Protein Processing [4]
Homeobox protein MOX-1 (MEOX1) OTJEMT2D MEOX1_HUMAN Gene/Protein Processing [4]
Homeobox protein unc-4 homolog OTOW7WTS UNC4_HUMAN Gene/Protein Processing [4]
Neurogenin-2 (NEUROG2) OTAEMIGT NGN2_HUMAN Gene/Protein Processing [4]
Oligodendrocyte transcription factor 3 (OLIG3) OTU8XLAF OLIG3_HUMAN Gene/Protein Processing [4]
Paired box protein Pax-3 (PAX3) OTN5PJZV PAX3_HUMAN Gene/Protein Processing [4]
Paired box protein Pax-6 (PAX6) OTOC9876 PAX6_HUMAN Gene/Protein Processing [4]

References

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