Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMHM93Y)

Drug Name
Meprobamate Drug Info
Synonyms
meprobamate; Meprospan; Meprobamat; Equanil; Miltown; Amepromat; Meprocompren; Meproban; Tranmep; Meprobam; Dapaz; Metractyl; Meprotabs; Meprosin; Meprodil; Mepiosine; Libiolan; Crestanil; Calmiren; Ayeramate; Andaksin; Anatimon; Anathylmon; Holbamate; Despasmol; Cirponyl; Biobamat; Neuramate; Metranquil; Meprocon; Mepantin; Lepetown; Ipsotian; Equilium; Equatrate; Carbaxin; Biobamate; Ansiatan; Anastress; Miltamato; Meprotil; Meprotan; Meprosan; Meproleaf; Meprindon; Mepranil; Mepavlon; Margonil; Harmonin; Dicandiol; Calmadin; Auxietil; Anxietil; Ansiowas; Amepromat; Amosene; Andaxin; Aneural; Aneurol; Aneusral; Aneuxal; Aneuxral; Ansietan; Ansil; Anural; Anzil; Apascil; Apasil; Appetrol; Arcoban; Arpon; Artolon; Ataraxine; Atraxin; Ayermate; Bamate; Brobamate; Calmax; Cirpon; Coprobate; Cypron; Cyrpon; Deprol; Diron; Diurnal; Diurnaldiverondormabrol; Diveron; Dormabrol; Ecuanil; Edenal; Enorden; Epicur; Epikur; Equinil; Equitar; Erina; Estasil; Gadexyl; Gagexyl; Hartol; Kessobamate; Klort; Larten; Lepenil; Letyl; Mendel; Mepamtin; Meposed; Mepriam; Meprin; Meprobamato; Meprobamatum; Meprodiol; Meprol; Meprosa; Meprotanum; Meproten; Meprovan; Meprovanmeprozine; Meprozine; Meptran; Meptranactylmilprem; Micrainin; Milpath; Milprem; Miltann; Miltaun; Miltuan; Miltwon; Misedant; Morbam; Multaun; Nephentine; Nervonus; Oasil; Optarket;Orlevol; Orolevol; Pancalma; Panediol; Pankalma; Pathibamate; Paxin; Pensive; Perequietil; Perequil; Perquietil; Pertranquil; Pimal; Placidon; Placitate; Prequil; Probamato; Probamyl; Probate; Procalmadiol; Procalmadol; Procalmidol; Procarbamide; Promate; Promato; Proquanil; Protran; Quaname; Quanane; Quanil; Quietidon; Quivet; Rastenil; Reostral; Restenil; Restenyl; Restinal; Restinil; Robamate;Sadanyl; Scolazil; Sedabamate; Sedanil; Sedanyl; Sedazil; Sedoquil; Sedoselecta; Selene; Seril; Setran; Shalvaton; Sowell; Spantran; Stensolo; Tamate; Tensol; Tensonal; Trancot; Trankvilan; Tranlisant; Tranquilan; Tranquilate; Tranquilax; Tranquiline; Tranquilsan; Tranquinol; Trelmar; Urbil; Urbilat; Vistabamate; Wardamate; Wyseals; Zirpon; Component of Appetrol; Component of Bamadex; Component of Equalysen; Component of Milpath; Component of Milprem; Component of Miltrate; Equanil suspension; Meprobamat [German]; Meprobamate and Aspirin Tablets; Meprobamato [Italian]; Meprobamic acid; Meprocon CMC; Solevione anastress; Bamd 400; Bamo 400; Canquil 400; Miltown 600; PMB 200; PMB 400; Apo-Meprobamate; Appetrol-Sr; Canquil-400; Component of PMB-400; Equanil (TN); Equazine-M; Fas-Cile; Fas-Cile 200; Kesso-Bamate; Mar-Bate; Meprin (VAN); Mepro-Aspirin; Mepro-analgesic; Meprobamato [INN-Spanish]; Meprobamatum [INN-Latin]; Meprospan (TN); Meprospan-200; Meprospan-400; Milprem-200; Milprem-400; Miltown (TN); My-trans; Neo-Tran; PMB-200; PMB-400; Pan-tranquil; Q-Gesic; SK-Bamate; Tranquiline (Intra); Vio-Bamate; Cap-O-Tran; Carbamic acid 2-methyl-2-propyltrimethylene ester; Meprobamate (JAN/USP/INN); Meprobamate [USAN:INN:BAN:JAN]; Carbamic acid, 2-methyl-2-propyltrimethylene ester; [2-(carbamoyloxymethyl)-2-methylpentyl] carbamate; {2-[(carbamoyloxy)methyl]-2-methylpentyl} carbamate; 1,3-Propanediol, 2-methyl-2-propyl-, 1,3-dicarbamate; 1,3-Propanediol, 2-methyl-2-propyl-, dicarbamate; 2,2-Di(carbamoyloxymethyl)pentane; 2-Methyl-2-n-propyl-1,3-propanediol dicarbamate; 2-Methyl-2-propyl-1,3-propanediol dicarbamate; 2-Methyl-2-propylpropane-1,3-diol dicarbamate; 2-Methyl-2-propyltrimethylene carbamate; 2-Metil-2-n-propil-1,3-propanediol dicarbamato; 2-Metil-2-n-propil-1,3-propanediol dicarbamato [Spanish]; 2-[(carbamoyloxy)methyl]-2-methylpentyl carbamate; 3P Bamate; KAI-1455
Indication
Disease Entry ICD 11 Status REF
Anxiety Approved [1]
Anxiety disorder 6B00-6B0Z Approved [2]
Malaria 1F40-1F45 Approved [3]
Ischemic reperfusion injury DB98.B Discontinued in Phase 1 [4]
Therapeutic Class
Antianxiety Agents
Cross-matching ID
PubChem CID
4064
ChEBI ID
CHEBI:6761
CAS Number
CAS 57-53-4
TTD Drug ID
DMHM93Y
INTEDE Drug ID
DR1029
ACDINA Drug ID
D00398

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DME
Drug Status:
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Protein kinase C epsilon (PRKCE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Bryostatin-1 DM1JOXY Alzheimer disease 8A20 Phase 2 [10]
RO-320432 DMFZ1YW N. A. N. A. Terminated [11]
LY-317644 DMM20PI N. A. N. A. Terminated [12]
CDE-6960 DMA0DKI Inflammation 1A00-CA43.1 Terminated [13]
RO-316233 DMAGLPW Discovery agent N.A. Investigative [14]
3,4-di-(4-methoxyphenyl)-1H-pyrrole-2,5-dione DMDO175 Discovery agent N.A. Investigative [15]
3,4-diphenyl-1H-pyrrole-2,5-dione DMPK6YT Discovery agent N.A. Investigative [15]
3-(4-methoxyphenyl)-4-phenyl-1H-pyrrole-2,5-dione DMGC7RY Discovery agent N.A. Investigative [15]
3-(indole-3-yl)-4-phenyl-1H-pyrrole-2,5-dione DM3EV9N Discovery agent N.A. Investigative [15]
LY-326449 DMN53M4 Discovery agent N.A. Investigative [16]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Targeting GABA(A) receptor alpha-1 (GABRA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [5]
Zolpidem DMWOSKJ Insomnia 7A00-7A0Z Approved [17]
Methoxyflurane DML0RAE Anaesthesia 9A78.6 Approved [5]
Nitrazepam DMEGIQ6 Epilepsy 8A60-8A68 Approved [5]
Allopregnanolone DMNLHAC Depression 6A70-6A7Z approved [18]
Clobazam - Lundbeck DMW1OQ0 Anxiety disorder 6B00-6B0Z Approved [5]
Hexobarbital DMQ314B Anaesthesia 9A78.6 Approved [5]
THIOCOLCHICOSIDE DMEPWYA Muscle spasm MB47.3 Approved [19]
Zaleplon DMGFWSM Insomnia 7A00-7A0Z Approved [20]
Ethchlorvynol DM53IP1 Insomnia 7A00-7A0Z Approved [5]
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Drug(s) Targeting Polypeptide deformylase (PDF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Proguanil DMBL79I Malaria 1F40-1F45 Approved [21]
Pralatrexate DMAO80I Breast cancer 2C60-2C65 Approved [22]
Ustekinumab DMHTYK3 Plaque psoriasis EA90.0 Approved [23]
Trimetrexate DMDEA85 Toxoplasmosis 1F57 Approved [24]
MCB-3837 DM0R4Z5 Malaria 1F40-1F45 Approved [3]
Chlorproguanil DM1IFGT Malaria 1F40-1F45 Approved [3]
LY333531 DMGMC8H Solid tumour/cancer 2A00-2F9Z Phase 2 [25]
Metoprine DM5GQD7 Advanced cancer 2A00-2F9Z Phase 2 [26]
Aminopterin DMQ9RBV leukaemia 2A60-2B33 Withdrawn from market [27]
2-Sulfhydryl-Ethanol DMJBO3D Discovery agent N.A. Investigative [28]
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Drug(s) Metabolized By UDP-glucuronosyltransferase 1A1 (UGT1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [29]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [30]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [31]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [32]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [33]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [34]
Mycophenolate mofetil DMPQAGE Hepatosplenic T-cell lymphoma Approved [35]
Metronidazole DMTIVEN Abscess Approved [36]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [37]
Ethanol DMDRQZU Chronic pain MG30 Approved [38]
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Drug(s) Metabolized By Cytochrome P450 2E1 (CYP2E1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Folic Acid DMEMBJC Colorectal carcinoma Approved [39]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [40]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [41]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [42]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [43]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [44]
Verapamil DMA7PEW Angina pectoris BA40 Approved [45]
Estrone DM5T6US Acne vulgaris ED80 Approved [46]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [47]
Ethanol DMDRQZU Chronic pain MG30 Approved [48]
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Drug(s) Metabolized By Mephenytoin 4-hydroxylase (CYP2C19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [49]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [50]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [51]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [52]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [45]
Verapamil DMA7PEW Angina pectoris BA40 Approved [53]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [54]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [55]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [56]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [57]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
GABA(A) receptor alpha-1 (GABRA1) TT1MPAY GBRA1_HUMAN Antagonist [5]
Polypeptide deformylase (PDF) TT9SL3Q DEFM_HUMAN Inhibitor [3]
Protein kinase C epsilon (PRKCE) TTBZ7OD KPCE_HUMAN Stimulator [6]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 2E1 (CYP2E1) DEVDYN7 CP2E1_HUMAN Substrate [7]
UDP-glucuronosyltransferase 1A1 (UGT1A1) DEYGVN4 UD11_HUMAN Substrate [8]
Mephenytoin 4-hydroxylase (CYP2C19) DEGTFWK CP2CJ_HUMAN Substrate [9]

References

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