Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMIUYFH)

Drug Name
Sulfapyridine Drug Info
Synonyms
Adiplon; Coccoclase; Dagenan; Eubasin; Eubasinum; Haptocil; Piridazol; Plurazol; Pyriamid; Pyridazol; Relbapiridina; Ronin;Septipulmon; Solfapiridina; Streptosilpyridine; Sulfapiridina; Sulfapyridinum; Sulfidin; Sulfidine; Sulphapyridin; Sulphapyridine; Thioseptal; Trianon; Solfapiridina [DCIT]; M and B 693; A-499; ALBB-006215; M + B 693; M&B 693; M+B 693; Sulfapiridina [INN-Spanish]; Sulfapyridine (TN); Sulfapyridinum [INN-Latin]; AO-801/41077453; N(1)-Pyridylsulfanilamide; N(sup1)-Pyridylsulfanilamide; N-2-Pyridylsulfanilamide; N1-2-Pyridylsulfanilamide; Sulfapyridine (USP/INN); Sulfapyridine [USAN:INN:BAN]; N'-2-Pyridylsulfanilide; N(1)-2-Pyridylsulfanilamide; N(sup 1)-2-Pyridylsulfanilamide; N1-(Pyridin-2-yl)sulfanilamide; Sulfanilamide, N1-2-pyridyl-(8CI); 2-(4-Aminobenzenesulfonamido)pyridine; 2-(p-Aminobenzenesulphonamido)pyridine; 2-Sulfanilamidopyridin; 2-Sulfanilamidopyridin [German]; 2-Sulfanilamidopyridine; 2-Sulfanilyl aminopyridine; 2-Sulfanilylaminopyridine; 2-Sulfapyridine; 4-(2-Pyridinylsulfonyl)aniline; 4-AMINO-N-2-PYRIDINYLBENZENESULFONAMIDE; 4-Amino-N,2-pyridinylbenzenesulfonamide; 4-Amino-N-2-pyridinyl-benzenesulfonamide; 4-Amino-N-[2-pyridyl]benzene sulfonamide; 4-[(2-Pyridylamino)sulfonyl]aniline; 4-amino-N-(pyridin-2-yl)benzenesulfonamide; 4-amino-N-pyridin-2-yl-benzenesulfonamide; 4-amino-N-pyridin-2-ylbenzenesulfonamide
Indication
Disease Entry ICD 11 Status REF
Dermatitis herpetiformis EB44 Approved [1]
Therapeutic Class
Dermatologic Agents
Cross-matching ID
PubChem CID
5336
ChEBI ID
CHEBI:132842
CAS Number
CAS 144-83-2
TTD Drug ID
DMIUYFH
INTEDE Drug ID
DR1512

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DME
DOT
Drug Status:
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Bacterial Dihydropteroate synthetase (Bact folP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sulfamethoxazole DMB08GE Acute otitis media AB00 Approved [7]
Sulfadiazine DMTW3R8 Rheumatic fever 1B40-1B42 Approved [8]
Doripenem DM9UCJK Cholecystitis Approved [9]
Colistin DMMD9QE Pseudomonas infection 1B92 Approved [10]
Sulphadoxine DMZI2UF Malaria 1F40-1F45 Approved [11]
Sulfisoxazole DMXLT8C Acute otitis media AB00 Approved [12]
Gramicidin D DMPT74U Bacterial infection 1A00-1C4Z Approved [13]
Oritavancin DM28D05 Bacterial infection 1A00-1C4Z Approved [9]
Faropenem DMX7A5V Gram-positive bacterial infection 1B74-1G40 Approved [9]
Daptomycin DMFDQ3I Bacterial infection 1A00-1C4Z Approved [14]
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Drug(s) Metabolized By RNA cytidine acetyltransferase (hALP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Folic Acid DMEMBJC Colorectal carcinoma Approved [15]
Caffeine DMKBJWP Allergic rhinitis CA08.0 Approved [16]
Procainamide DMNMXR8 Ventricular arrhythmias BC71 Approved [17]
Sulfamethoxazole DMB08GE Acute otitis media AB00 Approved [18]
Sulfadiazine DMTW3R8 Rheumatic fever 1B40-1B42 Approved [19]
Tobramycin DMUI0CH Bacteremia 1A73 Approved [20]
Mesalazine DMOL5IU Diverticulitis Approved [21]
Allopurinol DMLPAOB Gout FA25 Approved [22]
Netilmicin DMRD1QK Bacterial infection 1A00-1C4Z Approved [23]
Clonazepam DMTO13J Absence epilepsy Approved [24]
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Drug(s) Affected By Growth-regulated alpha protein (CXCL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [25]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [26]
Selenium DM25CGV N. A. N. A. Approved [27]
Methotrexate DM2TEOL Anterior urethra cancer Approved [28]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [29]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [30]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [31]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [32]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [31]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [33]
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Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [34]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [35]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [36]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [37]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [38]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [39]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [40]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [41]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [42]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [40]
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Drug(s) Affected By C-C motif chemokine 2 (CCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [43]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [44]
Gefitinib DM15F0X Colon adenocarcinoma Approved [45]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [46]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [47]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [48]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [49]
Methotrexate DM2TEOL Anterior urethra cancer Approved [50]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [51]
Quercetin DM3NC4M Obesity 5B81 Approved [52]
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Drug(s) Affected By Metalloproteinase inhibitor 2 (TIMP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [53]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [54]
Selenium DM25CGV N. A. N. A. Approved [55]
Quercetin DM3NC4M Obesity 5B81 Approved [56]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [57]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [58]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [59]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [60]
Tetracaine DM9J6C2 Spinal anesthesia MB40.3 Approved [61]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [62]
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Drug(s) Affected By Arylamine N-acetyltransferase 2 (NAT2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Procainamide DMNMXR8 Ventricular arrhythmias BC71 Approved [63]
Hydralazine DMU8JGH Chronic heart failure BD1Z Approved [64]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [65]
Sulfamethoxazole DMB08GE Acute otitis media AB00 Approved [66]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [67]
Quercetin DM3NC4M Obesity 5B81 Approved [68]
Testosterone DM7HUNW Hot flushes GA30 Approved [69]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [70]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
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Drug(s) Affected By Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [73]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [73]
Gefitinib DM15F0X Colon adenocarcinoma Approved [74]
Sunitinib DMCBJSR Acute undifferentiated leukemia Approved [75]
Rosuvastatin DMMIQ7G Arteriosclerosis BD40 Approved [76]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [77]
Methotrexate DM2TEOL Anterior urethra cancer Approved [78]
Quercetin DM3NC4M Obesity 5B81 Approved [79]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [80]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [81]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Bacterial Dihydropteroate synthetase (Bact folP) TT4ILYC DHPS_ECOLI Inhibitor [2]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
RNA cytidine acetyltransferase (hALP) Main DME DEZV4AP NAT10_HUMAN Substrate [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Arylamine N-acetyltransferase 2 (NAT2) OTBPDQOY ARY2_HUMAN Biotransformations [4]
Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2) OTW8V2V1 ABCG2_HUMAN Regulation of Drug Effects [4]
C-C motif chemokine 2 (CCL2) OTAD2HEL CCL2_HUMAN Protein Interaction/Cellular Processes [5]
Growth-regulated alpha protein (CXCL1) OT3WCTZV GROA_HUMAN Protein Interaction/Cellular Processes [5]
Interleukin-8 (CXCL8) OTS7T5VH IL8_HUMAN Protein Interaction/Cellular Processes [5]
Metalloproteinase inhibitor 2 (TIMP2) OT8S1RRP TIMP2_HUMAN Gene/Protein Processing [6]

References

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