Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMZSOG2)

Drug Name

STO609 Drug Info

Synonyms

STO-609; STO 609

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 3467590
ChEBI ID: CHEBI:92918
TTD Drug ID: DMZSOG2

Molecule-Related Drug Atlas

Molecule Type:

DTT

DOT

Drug Status:

Patented Agent(s)

Investigative Drug(s)

Approved Drug(s)

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Calmodulin-dependent kinase II (CAMKK2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
US9623028, Compound 101	DM6F7M2	N. A.	N. A.	Patented	[5]
CQ7	DMXP073	N. A.	N. A.	Patented	[5]
US9623028, Compound 79	DMMSHX4	N. A.	N. A.	Patented	[5]
PMID22136433C20	DMI8217	Discovery agent	N.A.	Investigative	[6]
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Drug(s) Affected By Cytochrome P450 1A1 (CYP1A1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Amodiaquine	DME4RA8	Malaria	1F40-1F45	Approved	[7]
Riluzole	DMECBWN	Amyotrophic lateral sclerosis	8B60.0	Approved	[8]
Flutamide	DMK0O7U	Prostate cancer	2C82.0	Approved	[9]
Menadione	DMSJDTY	Vitamin K deficiency	5B59	Approved	[10]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[11]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[12]
Ethacrynic acid	DM60QMR	Edema	MG29	Approved	[13]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[14]
Ethinyl Estradiol	DMODJ40	Acne vulgaris	ED80	Approved	[15]
Clofibrate	DMPC1J7	Dysbetalipoproteinemia	5C80.2	Approved	[16]
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Drug(s) Affected By Interleukin-8 (CXCL8)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrocortisone	DMGEMB7	Acne vulgaris	ED80	Approved	[17]
Nicotine	DMWX5CO	Lung cancer	2C25.0	Approved	[18]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[19]
Pantothenic acid	DM091H2	Vitamin deficiency	5B55-5B71	Approved	[20]
Mechlorethamine	DM0CVXA	Chronic myelogenous leukaemia	2A20.0	Approved	[21]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[22]
Fexofenadine	DM17ONX	Allergic rhinitis	CA08.0	Approved	[23]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[24]
Nitric Oxide	DM1RBYG	Hypertension	BA00-BA04	Approved	[25]
Lumiracoxib	DM1S4AG	Chronic renal failure	GB61.Z	Approved	[23]
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Drug(s) Affected By Integrin beta-7 (ITGB7)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[26]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[27]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[28]
Diethylstilbestrol	DMN3UXQ	Gonorrheal vaginitis	GA02	Approved	[29]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[30]
Tamibarotene	DM3G74J	T-cell leukaemia	2A90	Phase 3	[27]
(+)-JQ1	DM1CZSJ	Testicular cancer	2C80	Phase 1	[31]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[32]
Formaldehyde	DM7Q6M0	Discovery agent	N.A.	Investigative	[33]
Sulforaphane	DMQY3L0	Skin disease	EA00-EM0Z	Investigative	[34]
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Drug(s) Affected By Aryl hydrocarbon receptor (AHR)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[35]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[36]
Citalopram	DM2G9AE	Acute coronary syndrome	BA41	Approved	[37]
Colchicine	DM2POTE	Acute gout flare	FA25.0	Approved	[38]
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[39]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[40]
Omeprazole	DM471KJ	Cystic fibrosis	CA25	Approved	[41]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[42]
Rifampicin	DM5DSFZ	Non-insulin dependent diabetes	5A11	Approved	[43]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[44]
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Drug(s) Affected By Cytochrome P450 1B1 (CYP1B1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Flutamide	DMK0O7U	Prostate cancer	2C82.0	Approved	[8]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[45]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[46]
Progesterone	DMUY35B	Amenorrhea	GA20.0	Approved	[47]
Estrone	DM5T6US	Acne vulgaris	ED80	Approved	[48]
Melatonin	DMKWFBT	Depression	6A70-6A7Z	Approved	[49]
Vitamin A	DMJ2AH4	Night blindness	9D45	Approved	[50]
Amodiaquine	DME4RA8	Malaria	1F40-1F45	Approved	[51]
Daunorubicin	DMQUSBT	Acute monocytic leukemia		Approved	[52]
Pantothenic acid	DM091H2	Vitamin deficiency	5B55-5B71	Approved	[20]
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Drug(s) Affected By Prothrombin (F2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Colchicine	DM2POTE	Acute gout flare	FA25.0	Approved	[53]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[54]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[55]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[56]
Chlorpromazine	DMBGZI3	Acute intermittent hepatic porphyria	5C58.11	Approved	[57]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[58]
Phytonadione	DM8HDOL	Bleeding disorder	GA20-GA21	Approved	[59]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[60]
Testosterone enanthate	DMB6871	N. A.	N. A.	Approved	[61]
Atorvastatin	DMF28YC	Acute coronary syndrome	BA41	Approved	[62]
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Drug(s) Affected By Proline-rich AKT1 substrate 1 (AKT1S1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[63]
Capivasertib	DM9SKW8	Breast cancer	2C60-2C65	Approved	[64]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[65]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[66]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[67]
Zoledronate	DMIXC7G	Adenocarcinoma	2D40	Approved	[68]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[69]
Cabazitaxel	DMPAZHC	Breast cancer	2C60-2C65	Approved	[70]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[71]
Urethane	DM7NSI0	N. A.	N. A.	Phase 4	[72]
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Drug(s) Affected By Serine/threonine-protein kinase STK11 (STK11)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[73]
Selenium	DM25CGV	N. A.	N. A.	Approved	[74]
Ergotidine	DM78IME	Osteoarthritis	FA00-FA05	Approved	[4]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[66]
2-deoxyglucose	DMIAHVU	Solid tumour/cancer	2A00-2F9Z	Approved	[75]
Pioglitazone	DMKJ485	Amyotrophic lateral sclerosis	8B60.0	Approved	[76]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[77]
Resveratrol	DM3RWXL	Giant cell arteritis	4A44.2	Phase 3	[78]
APR-246	DMNFADH	Ovarian cancer	2C73	Phase 2	[79]
GDC-0980/RG7422	DMF3MV1	Non-hodgkin lymphoma	2B33.5	Phase 2	[80]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Calmodulin-dependent kinase II (CAMKK2)	TTV298Y	KKCC2_HUMAN	Inhibitor	[1]
CaM-kinase IV kinase (CAMKK1)	TTGLQWZ	KKCC1_HUMAN	Inhibitor	[1]

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Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
Aryl hydrocarbon receptor (AHR)	OTFE4EYE	AHR_HUMAN	Gene/Protein Processing	[2]
Cytochrome P450 1A1 (CYP1A1)	OTE4EFH8	CP1A1_HUMAN	Gene/Protein Processing	[2]
Cytochrome P450 1B1 (CYP1B1)	OTYXFLSD	CP1B1_HUMAN	Gene/Protein Processing	[2]
Integrin beta-7 (ITGB7)	OT33UUKU	ITB7_HUMAN	Gene/Protein Processing	[2]
Interleukin-8 (CXCL8)	OTS7T5VH	IL8_HUMAN	Gene/Protein Processing	[2]
Proline-rich AKT1 substrate 1 (AKT1S1)	OT4JHN4Y	AKTS1_HUMAN	Post-Translational Modifications	[3]
Prothrombin (F2)	OTNFSM49	THRB_HUMAN	Protein Interaction/Cellular Processes	[4]
Serine/threonine-protein kinase STK11 (STK11)	OT1YZSP3	STK11_HUMAN	Drug Response	[4]

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References

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