General Information of Drug (ID: DMELOIQ)

Drug Name
ALPHA-NAPHTHOFLAVONE Drug Info
Synonyms
7,8-Benzoflavone; alpha-Naphthoflavone; 604-59-1; 2-Phenyl-4H-benzo[h]chromen-4-one; alpha-Naphthylflavone; 2-phenylbenzo[h]chromen-4-one; Benzo(h)flavone; 7,8-BF; 4H-Naphtho[1,2-b]pyran-4-one, 2-phenyl-; .alpha.-Naphthoflavone; 2-Phenyl-benzo[h]chromen-4-one; 2-Phenyl-4H-naphtho(1,2-b)pyran-4-one; CCRIS 3607; 2-Phenylbenzo(h)chromen-4-one; EINECS 210-071-1; UNII-FML65D8PY5; NSC 407011; BRN 0210862; FML65D8PY5; benzo[h]flavone; MLS003171601; CHEMBL283196; CHEBI:76995; VFMMPHCGEFXGIP-UHFFFAOYSA-N; 4H-NAPHTHO(1,2-b)PYRAN-4-ONE, 2-PH
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
11790
ChEBI ID
CHEBI:76995
CAS Number
CAS 604-59-1
TTD Drug ID
DMELOIQ
VARIDT Drug ID
DR01402

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Patented Agent(s)
Drug(s) Targeting Aromatase (CYP19A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Anastrozole DMNP60F Breast cancer 2C60-2C65 Approved [11]
Letrozole DMH07Y3 Estrogen-receptor positive breast cancer Approved [12]
Exemestane DM9HPW3 Hormonally-responsive breast cancer 2C60-2C65 Approved [12]
Aminoglutethimide DMWFHMZ Cushing disease 5A70 Approved [13]
FADROZOLE DM3C5GZ Breast cancer 2C60-2C65 Approved [14]
Testolactone DMVY4GN Breast cancer 2C60-2C65 Approved [15]
LIAROZOLE DM4OYXE Dermatological disease DA24.Y Phase 2/3 [2]
Coumate DMVKW0N Breast cancer 2C60-2C65 Phase 2 [16]
BGS-649 DMO4MNQ Endometriosis GA10 Phase 2 [17]
NARINGENIN DMHAZLM N. A. N. A. Phase 1 [2]
Letrozole DMH07Y3 Estrogen-receptor positive breast cancer Approved [76]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [77]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [78]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [79]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [78]
Methotrexate DM2TEOL Anterior urethra cancer Approved [80]
FADROZOLE DM3C5GZ Breast cancer 2C60-2C65 Approved [81]
Bifonazole DM3KN7V Fungal infection 1F29-1F2F Approved [82]
Quercetin DM3NC4M Obesity 5B81 Approved [83]
Fluoxetine DM3PD2C Bipolar depression Approved [78]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
M3814 DMK2L38 Locally advanced rectal cancer 2B92 Phase 1/2 [18]
AZD7648 DMD9Y5T Solid tumour/cancer 2A00-2F9Z Phase 1/2 [19]
M9831 DM59TI2 Solid tumour/cancer 2A00-2F9Z Phase 1 [18]
PP121 DMU8KTO Discovery agent N.A. Investigative [20]
LY-292223 DML36ZE Discovery agent N.A. Investigative [21]
Ethyl 1-[(1H-benzimidazol-2(3H)one-5-yl)sulfonyl]-1H-pyrrole-2-carboxylate DM3FH02 Discovery agent N.A. Investigative [22]
PIK-75 DM9BQTX Discovery agent N.A. Investigative [23]
KU-0060648 DMQWS6U Discovery agent N.A. Investigative [24]
2-Morpholin-4-yl-pyrimido[2,1-a]isoquinolin-4-one DM79ZOV Discovery agent N.A. Investigative [1]
2-(2-Methyl-morpholin-4-yl)-benzo[h]chromen-4-one DMAHZR9 Discovery agent N.A. Investigative [21]
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Drug(s) Affected By Cytochrome P450 2J2 (CYP2J2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [25]
Quercetin DM3NC4M Obesity 5B81 Approved [26]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [27]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [28]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [29]
Nisoldipine DM7ISKJ Hypertension BA00-BA04 Approved [25]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [30]
Amlodipine DMBDAZV Angina pectoris BA40 Approved [25]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [31]
Gemfibrozil DMD8Q3J Hyperlipidaemia 5C80 Approved [32]
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Drug(s) Affected By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Eplerenone DMF0NQR Heart failure BD10-BD13 Approved [33]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [34]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [35]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [36]
Proguanil DMBL79I Malaria 1F40-1F45 Approved [37]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [37]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [38]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [39]
Capsaicin DMGMF6V Back pain ME84.Z Approved [40]
Axitinib DMGVH6N Renal cell carcinoma 2C90 Approved [41]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Busulfan DMXYJ9C Chronic myelogenous leukaemia 2A20.0 Approved [42]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [43]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [44]
Chlorambucil DMRKE63 Chronic lymphocytic leukaemia 2A82.0 Approved [44]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [45]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [46]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [47]
Selenium DM25CGV N. A. N. A. Approved [48]
Etretinate DM2CZFA Keratosis ED56 Approved [49]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [50]
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Drug(s) Affected By Transcription factor 7 (TCF7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [51]
Tibolone DM78XFG Anabolic metabolism 5C50-5C8Z Approved [52]
Testosterone DM7HUNW Hot flushes GA30 Approved [53]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [54]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [55]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [56]
Bortezomib DMNO38U Leukemia Approved [57]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [58]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [59]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [60]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [61]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [62]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [63]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [64]
Testosterone DM7HUNW Hot flushes GA30 Approved [65]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [65]
Leflunomide DMR8ONJ Arthritis FA20 Approved [66]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [67]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [67]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [30]
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Drug(s) Affected By Cytochrome P450 1A2 (CYP1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zolmitriptan DM1IB4Q Migraine 8A80 Approved [68]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [68]
Etoricoxib DM6A4NW Rheumatoid arthritis FA20 Approved [68]
Capsaicin DMGMF6V Back pain ME84.Z Approved [69]
Hesperetin DMKER83 High blood cholesterol level 5C80.00 Approved [70]
Stiripentol DMMSDOY Dravet syndrome 8A61.11 Approved [71]
Nifedipine DMSVOZT Angina pectoris BA40 Approved [72]
Zileuton DMVRIC2 Allergic asthma CA23.0 Approved [73]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [74]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [75]
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Drug(s) Affected By Cytochrome P450 1A1 (CYP1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [84]
Riluzole DMECBWN Amyotrophic lateral sclerosis 8B60.0 Approved [85]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [86]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [87]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [88]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [89]
Ethacrynic acid DM60QMR Edema MG29 Approved [90]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [91]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [92]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [93]
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Drug(s) Affected By Interleukin-6 (IL6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [94]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [95]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [96]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [97]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [98]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [99]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [100]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [101]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [102]
Methotrexate DM2TEOL Anterior urethra cancer Approved [94]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [103]
FADROZOLE DM3C5GZ Breast cancer 2C60-2C65 Approved [81]
Quercetin DM3NC4M Obesity 5B81 Approved [8]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Ethanol DMDRQZU Chronic pain MG30 Approved [105]
Potassium Chloride DMMTAJC Hypokalemia 5C77 Approved [106]
Mitotane DMU1GX0 Adrenocortical carcinoma 2D11.Z Approved [107]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [75]
Dalcetrapib DMKNCVM Acute coronary syndrome BA41 Phase 3 [108]
Anacetrapib DMP2BFG Arteriosclerosis BD40 Phase 3 [108]
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Drug(s) Affected By Interleukin-1 beta (IL1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [109]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [99]
Gefitinib DM15F0X Colon adenocarcinoma Approved [110]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [111]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [112]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [111]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [101]
Selenium DM25CGV N. A. N. A. Approved [113]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [114]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [115]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [96]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [99]
Quercetin DM3NC4M Obesity 5B81 Approved [26]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [116]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [116]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [117]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [118]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [119]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [120]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [121]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [122]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [123]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [124]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [97]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [125]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [99]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [111]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [112]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [126]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [111]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By C-C motif chemokine 2 (CCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [98]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [79]
Gefitinib DM15F0X Colon adenocarcinoma Approved [127]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [100]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [128]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [129]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [130]
Methotrexate DM2TEOL Anterior urethra cancer Approved [80]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [131]
Quercetin DM3NC4M Obesity 5B81 Approved [132]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [94]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [133]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [94]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [135]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [136]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [137]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [120]
Leflunomide DMR8ONJ Arthritis FA20 Approved [66]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [138]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Eicosapentaenoic acid/docosa-hexaenoic acid DMMUCG4 Hypertriglyceridemia 5C80.1 Approved [139]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [140]
Gamolenic acid DMQN30Z Allergy 4A80-4A85 Approved [141]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [142]
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [143]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [144]
Ibandronate DM0QZBN Hypercalcaemia 5B91.0 Approved [145]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [79]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [111]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [146]
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Drug(s) Affected By Cytochrome P450 1B1 (CYP1B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [85]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [147]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [148]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [149]
Estrone DM5T6US Acne vulgaris ED80 Approved [150]
Melatonin DMKWFBT Depression 6A70-6A7Z Approved [151]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [152]
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [153]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [154]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [97]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [155]
Adenosine DMM2NSK Paroxysmal supraventricular tachycardia BC81.Z Approved [75]
Etretinate DM2CZFA Keratosis ED56 Approved [49]
Quercetin DM3NC4M Obesity 5B81 Approved [156]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [157]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [63]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [158]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [159]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [160]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [161]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [162]
Etretinate DM2CZFA Keratosis ED56 Approved [49]
Quercetin DM3NC4M Obesity 5B81 Approved [26]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [62]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [163]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [164]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [165]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [160]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [161]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [121]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [48]
Quercetin DM3NC4M Obesity 5B81 Approved [166]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [62]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [164]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [30]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [161]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [167]
Benzatropine DMF7EXL Parkinsonian disorder Approved [168]
Clozapine DMFC71L Schizophrenia 6A20 Approved [168]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [169]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [158]
Leflunomide DMR8ONJ Arthritis FA20 Approved [66]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [170]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [58]
Urethane DM7NSI0 N. A. N. A. Phase 4 [171]
Epigallocatechin gallate DMCGWBJ Hepatic fibrosis DB93.0 Phase 3 [172]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [173]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [174]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [175]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [176]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [167]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [177]
Clotrimazole DMMFCIH Cutaneous candidiasis 1F23.14 Approved [176]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [60]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [178]
DTI-015 DMXZRW0 Brain cancer 2A00 Approved [179]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [180]
Bardoxolone methyl DMODA2X Mixed connective tissue disease 4A43.3 Phase 3 [181]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [182]
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [183]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [184]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [168]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [185]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [186]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [185]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [157]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [187]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [63]
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Drug(s) Affected By Hexokinase-1 (HK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [188]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [189]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [138]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [167]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [190]
Mebendazole DMO14SG Ascariasis 1F62 Approved [191]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [58]
Arsenic DMTL2Y1 N. A. N. A. Approved [192]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [193]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phosphoglucomutase-1 (PGM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [26]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [194]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [195]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [196]
Panobinostat DM58WKG Chronic graft versus host disease Approved [188]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [30]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [121]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [197]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [167]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [48]
Etretinate DM2CZFA Keratosis ED56 Approved [49]
Methotrexate DM2TEOL Anterior urethra cancer Approved [198]
Quercetin DM3NC4M Obesity 5B81 Approved [199]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [157]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [200]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [201]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [30]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [161]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [121]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Etretinate DM2CZFA Keratosis ED56 Approved [202]
FADROZOLE DM3C5GZ Breast cancer 2C60-2C65 Approved [81]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [203]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [204]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [205]
Testosterone DM7HUNW Hot flushes GA30 Approved [205]
Pyruvic acid DM7Q41G Malnutrition 5B50-5B71 Approved [206]
Topiramate DM82Z30 Alcohol dependence 6C40.2 Approved [207]
Lamotrigine DM8SXYG Bipolar disorder 6A60 Approved [207]
ABIRATERONE DM8V75C Prostate cancer 2C82.0 Approved [208]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [209]
Methotrexate DM2TEOL Anterior urethra cancer Approved [80]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [210]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [211]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [212]
Paclitaxel DMLB81S Breast carcinoma Approved [213]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [214]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [215]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [216]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [217]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Progesterone receptor (PGR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [218]
Drospirenone DM1A9W3 Acne vulgaris ED80 Approved [219]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [220]
Estrone DM5T6US Acne vulgaris ED80 Approved [221]
Tibolone DM78XFG Anabolic metabolism 5C50-5C8Z Approved [222]
Testosterone DM7HUNW Hot flushes GA30 Approved [223]
Exemestane DM9HPW3 Hormonally-responsive breast cancer 2C60-2C65 Approved [224]
Goserelin DMAT8CG Breast cancer 2C60-2C65 Approved [225]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [226]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Androgen receptor (AR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [227]
Nilutamide DMFN07X Prostate cancer 2C82.0 Approved [227]
Hydroxyflutamide DMGIZF5 Prostate cancer 2C82.0 Approved [227]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [228]
Bicalutamide DMZMSPF Prostate cancer 2C82.0 Approved [229]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [218]
Drospirenone DM1A9W3 Acne vulgaris ED80 Approved [230]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [231]
Selenium DM25CGV N. A. N. A. Approved [232]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [233]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [79]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [234]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [235]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [236]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [237]
Quercetin DM3NC4M Obesity 5B81 Approved [238]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [239]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [157]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [240]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [241]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Aromatase (CYP19A1) TTSZLWK CP19A_HUMAN Inhibitor [2]
DNA-dependent protein kinase catalytic (PRKDC) TTK3PY9 PRKDC_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Androgen receptor (AR) OTUBKAZZ ANDR_HUMAN Gene/Protein Processing [3]
Aromatase (CYP19A1) OTZ6XF74 CP19A_HUMAN Gene/Protein Processing [4]
Aryl hydrocarbon receptor (AHR) OTFE4EYE AHR_HUMAN Gene/Protein Processing [3]
ATP-dependent 6-phosphofructokinase, muscle type (PFKM) OT1QY9JM PFKAM_HUMAN Gene/Protein Processing [5]
Bisphosphoglycerate mutase (BPGM) OTFX6527 PMGE_HUMAN Gene/Protein Processing [5]
C-C motif chemokine 2 (CCL2) OTAD2HEL CCL2_HUMAN Gene/Protein Processing [6]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Gene/Protein Processing [7]
Cytochrome P450 11B1, mitochondrial (CYP11B1) OTKKL894 C11B1_HUMAN Gene/Protein Processing [8]
Cytochrome P450 1A1 (CYP1A1) OTE4EFH8 CP1A1_HUMAN Gene/Protein Processing [9]
Cytochrome P450 1A2 (CYP1A2) OTLLBX48 CP1A2_HUMAN Gene/Protein Processing [10]

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