Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMXYLQ3)

Drug Name
Lansoprazole Drug Info
Synonyms
Lancid; Lanproton; Lansopep; Lansoprazol; Lansoprazol [INN-Spanish]; Lansoprazole [USAN:BAN:INN]; Lansoprazolum; Lansoprazolum [INN-Latin]; Lansox; Lanston; Lanzol-30; Lanzopral; Lanzor; Lasoprol; Limpidex; Mesactol; Monolitum; Ogastro; Opiren; Agopton; Aprazol; Bamalite; Blason; Compraz; Ilsatec; Ketian; Prevacid; Prevacid 24HR; Prevacid Iv; Prevacid NapraPAC; Prevacid SoluTab; Prezal; Pro Ulco; Prosogan; Suprecid; Takepron; Zoprol; lansoprazole; 103577-45-3; A-65006; AG 1749; AG-1749; CHEBI:6375; Dakar; HSDB 7204; Lanz; Lanzo; Ogast; Promp; Ulpax; Zoton
Indication
Disease Entry ICD 11 Status REF
Gastric ulcer DA60 Approved [1]
Gastrinoma 2C10.1 Approved [1]
Peptic ulcer DA61 Approved [1]
Cross-matching ID
PubChem CID
3883
ChEBI ID
CHEMBL480
CAS Number
CAS 103577-45-3
TTD Drug ID
DMXYLQ3
INTEDE Drug ID
DR0915

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [13]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [14]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [15]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [16]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [17]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [18]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [19]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [20]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [14]
Verapamil DMA7PEW Angina pectoris BA40 Approved [3]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Metabolized By Cytochrome P450 2C18 (CYP2C18)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [21]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [22]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [23]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [21]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [24]
Diazepam DM08E9O Alcohol withdrawal Approved [25]
Methadone DMTW6IU Advanced cancer 2A00-2F9Z Approved [26]
Dapsone DM4LT8A Acne vulgaris ED80 Approved [27]
Lidocaine DML4ZOT Anaesthesia 9A78.6 Approved [21]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [28]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Metabolized By Cytochrome P450 2C8 (CYP2C8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [29]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [30]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [30]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [21]
Verapamil DMA7PEW Angina pectoris BA40 Approved [31]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [32]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [33]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [30]
Mycophenolate mofetil DMPQAGE Hepatosplenic T-cell lymphoma Approved [34]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [23]
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Drug(s) Metabolized By Cytochrome P450 2C9 (CYP2C9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Progesterone DMUY35B Amenorrhea GA20.0 Approved [35]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [36]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [37]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [21]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [38]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [21]
Verapamil DMA7PEW Angina pectoris BA40 Approved [39]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [40]
Estrone DM5T6US Acne vulgaris ED80 Approved [41]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [42]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Metabolized By Mephenytoin 4-hydroxylase (CYP2C19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [43]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [35]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [44]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [45]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [21]
Verapamil DMA7PEW Angina pectoris BA40 Approved [46]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [22]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [42]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [47]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [23]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP-dependent translocase ABCB1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [48]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [49]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [50]
Lamotrigine DM8SXYG Bipolar disorder 6A60 Approved [51]
Cepharanthine DM9Y5JB N. A. N. A. Approved [52]
Itraconazole DMCR1MV Aspergillosis 1F20 Approved [53]
Clozapine DMFC71L Schizophrenia 6A20 Approved [54]
Midostaurin DMI6E0R Acute myeloid leukaemia 2A60 Approved [55]
Trifluoperazine DMKBYWI Anxiety Approved [56]
Olanzapine DMPFN6Y Bipolar depression Approved [54]
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Drug(s) Affected By Nuclear receptor subfamily 1 group I member 2 (NR1I2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [9]
Vidarabine DM0N85H Hepatosplenic T-cell lymphoma Approved [9]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [57]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [58]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [59]
Etidronic acid DM1XHYJ Bone Paget disease Approved [9]
Tiaprofenic acid DM23D7J Osteoarthritis FA00-FA05 Approved [9]
Bromperidol DM24XYQ Schizophrenia 6A20 Approved [9]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [60]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [61]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phospholipid-transporting ATPase ABCA1 (ABCA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [62]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [63]
Quercetin DM3NC4M Obesity 5B81 Approved [64]
Fluoxetine DM3PD2C Bipolar depression Approved [65]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [66]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [67]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [11]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [68]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [69]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [70]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pro-opiomelanocortin (POMC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [71]
Prednisone DM2HG4X Acute asthma CA23 Approved [72]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [73]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [74]
Fentanyl DM8WAHT Analgesia MB40.8 Approved [75]
Cyproheptadine DM92AH3 Allergic rhinitis CA08.0 Approved [76]
Triamcinolone DM98IXF Acute adrenal insufficiency Approved [77]
Buspirone DMBS632 Anxiety disorder 6B00-6B0Z Approved [78]
Ethanol DMDRQZU Chronic pain MG30 Approved [79]
Metyrapone DMI7FVQ Cushing disease 5A70 Approved [80]
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Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [81]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [82]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [83]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [84]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [85]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [86]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [87]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [88]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [89]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [87]
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Drug(s) Affected By Phosphoethanolamine/phosphocholine phosphatase (PHOSPHO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
SPI-1005 DM6XFHS Reperfusion injury ND56.Z Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Folic Acid DMEMBJC Colorectal carcinoma Approved [91]
Mivebresib DMCPF90 Acute myeloid leukaemia 2A60 Phase 1 [92]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [93]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [94]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [95]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) Main DME DE4LYSA CP3A4_HUMAN Substrate [2]
Cytochrome P450 2C9 (CYP2C9) DE5IED8 CP2C9_HUMAN Substrate [3]
Mephenytoin 4-hydroxylase (CYP2C19) Main DME DEGTFWK CP2CJ_HUMAN Substrate [4]
Cytochrome P450 2C8 (CYP2C8) DES5XRU CP2C8_HUMAN Substrate [5]
Cytochrome P450 2C18 (CYP2C18) DEZMWRE CP2CI_HUMAN Substrate [6]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Drug Response [7]
Interleukin-8 (CXCL8) OTS7T5VH IL8_HUMAN Gene/Protein Processing [8]
Nuclear receptor subfamily 1 group I member 2 (NR1I2) OTC5U0N5 NR1I2_HUMAN Gene/Protein Processing [9]
Phosphoethanolamine/phosphocholine phosphatase (PHOSPHO1) OT43A0JA PHOP1_HUMAN Gene/Protein Processing [10]
Phospholipid-transporting ATPase ABCA1 (ABCA1) OT94G6BQ ABCA1_HUMAN Gene/Protein Processing [11]
Pro-opiomelanocortin (POMC) OTV41F7T COLI_HUMAN Gene/Protein Processing [12]

References

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