General Information of Disease (ID: DISSZ04P)

Disease Name Colonic neoplasm
Synonyms
colon neoplasm (disease); colonic tumour; tumor of the colon; colon tumor; tumour of colon; colon neoplasm; colonic tumor; colon tumour; tumour of the colon; neoplasm of colon; colonic neoplasm; tumor of colon; neoplasm of the colon
Definition
A benign or malignant neoplasm that affects the colon. Representative examples of benign neoplasms include lipoma and leiomyoma. Representative examples of malignant neoplasms include carcinoma, lymphoma, and sarcoma. Colonic adenomas always exhibit epithelial dysplasia and are considered premalignant neoplasms.
Disease Hierarchy
DISTBY9Z: Tumour
DISR1UCN: Colorectal neoplasm
DISXXS3L: Colonic disorder
DISSZ04P: Colonic neoplasm
Disease Identifiers
MONDO ID
MONDO_0005401
MESH ID
D003110
UMLS CUI
C0009375
MedGen ID
3165
HPO ID
HP:0100273
SNOMED CT ID
126838000

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 214 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
ALOX12B TTQ4QQH Limited Biomarker [1]
BECN1 TT5M7LN Limited Altered Expression [2]
BIRC5 TTTPU1G Limited Biomarker [3]
BRD4 TTSRAOU Limited Biomarker [4]
CHEK2 TT9ABMF Limited Biomarker [5]
CYP2A6 TTAQ6ZW Limited Biomarker [6]
ERBB3 TTSINU2 Limited Genetic Variation [7]
FGFBP1 TTV1YFT Limited Biomarker [8]
GRIK2 TT0K5RG Limited Biomarker [9]
GRPR TTC1MVT Limited Genetic Variation [10]
HSPB1 TT9AZWY Limited Biomarker [11]
LAPTM4B TTEJQT0 Limited Genetic Variation [12]
LTB4R TTN53ZF Limited Biomarker [13]
MDM2 TT9TE0O Limited Biomarker [14]
ODC1 TTUMGNO Limited Biomarker [15]
PRKG1 TT7IZSA Limited Altered Expression [16]
PRSS1 TT2WR1T Limited Altered Expression [17]
RECK TTRZBW7 Limited Altered Expression [18]
TGFBR2 TTZE3P7 Limited Genetic Variation [19]
TP53BP1 TTX4UE9 Limited Biomarker [9]
CYSLTR1 TTGKOY9 Disputed Altered Expression [20]
ERBB2 TTR5TV4 Disputed Altered Expression [21]
HDAC3 TT4YWTO Disputed Biomarker [22]
HRH2 TTQHJ1K Disputed Genetic Variation [23]
HRH4 TTXJ178 Disputed Genetic Variation [23]
LGR5 TTTSGRH Disputed Biomarker [24]
MSR1 TT2TDH9 Disputed Altered Expression [25]
MST1R TTBQ3OC Disputed Altered Expression [26]
PLA2G1B TT9V5JH Disputed Altered Expression [27]
PROM1 TTXMZ81 Disputed Biomarker [28]
SP1 TTZEP6S Disputed Altered Expression [29]
SRC TT6PKBN Disputed Altered Expression [30]
TACSTD2 TTP2HE5 Disputed Biomarker [31]
TNFSF10 TTA5MS9 Disputed Biomarker [32]
BAP1 TT47RXJ moderate Biomarker [33]
BIRC3 TTAIWZN moderate Biomarker [34]
CASP6 TTKW4ML moderate Biomarker [35]
CCND1 TTFCJ7S moderate Biomarker [36]
CDKN2A TTFTWQ8 moderate Altered Expression [37]
DPYD TTZPS91 moderate Biomarker [38]
F5 TT1O264 moderate Biomarker [39]
GAST TT4LRVO moderate Altered Expression [40]
HMGCS2 TTS0EZJ moderate Biomarker [41]
IGF2 TTE8WGO moderate Altered Expression [42]
LEP TTBJEZ5 moderate Biomarker [43]
MUTYH TTNB0ZK moderate Biomarker [44]
PLA2G7 TTDNFMT moderate Biomarker [45]
PLD2 TTRLMKF moderate Altered Expression [46]
PTP4A3 TT7YM8D moderate Biomarker [47]
SUV39H1 TTUWQTK moderate Altered Expression [48]
TIE1 TTT4236 moderate Altered Expression [49]
TNFRSF10A TT5WLRX moderate Biomarker [50]
ACVR2A TTX2DRI Strong Biomarker [51]
ADCYAP1R1 TT5OREU Strong Altered Expression [52]
ADORA3 TTJFY5U Strong Biomarker [53]
ADRB3 TTMXGCW Strong Altered Expression [54]
AHCY TTE2KUJ Strong Biomarker [55]
ALOX5 TTSJ6Q4 Strong Biomarker [1]
ASAP3 TTB4ZEN Strong Biomarker [56]
ATP2A2 TTE6THL Strong Genetic Variation [57]
AURKA TTPS3C0 Strong Genetic Variation [58]
BAK1 TTFM7V0 Strong Biomarker [59]
BAX TTQ57WJ Strong Biomarker [60]
BCL2 TTFOUV4 Strong Biomarker [3]
CA4 TTZHA0O Strong Biomarker [61]
CACNA2D1 TTFK1JQ Strong Biomarker [61]
CBR1 TTVG0SN Strong Biomarker [62]
CCKBR TTVFO0U Strong Genetic Variation [63]
CCL20 TT2XAZY Strong Biomarker [61]
CCNE1 TTCEJ4F Strong Biomarker [64]
CD248 TTYJWT7 Strong Altered Expression [65]
CDKN1A TT9GUW0 Strong Altered Expression [66]
CEACAM1 TTA9CK4 Strong Altered Expression [67]
CEACAM3 TTPX7I5 Strong Biomarker [68]
CEACAM5 TTY6DTE Strong Biomarker [68]
CEACAM6 TTIGH2W Strong Biomarker [69]
CHKA TT10AWB Strong Biomarker [70]
CHRM1 TTZ9SOR Strong Biomarker [71]
CHRNA7 TTLA931 Strong Biomarker [72]
CHUK TT1F8OQ Strong Biomarker [73]
CLIC1 TT8KZG6 Strong Altered Expression [74]
CLN3 TTORF9W Strong Altered Expression [75]
COL18A1 TT63DI9 Strong ModifyingMutation [76]
CRY1 TT5MLZR Strong Altered Expression [77]
CRYAB TT7RUHB Strong Biomarker [61]
CSK TTX6F0Q Strong Biomarker [78]
CSNK1A1 TTFQEMX Strong Genetic Variation [79]
CTNNB1 TTRPKQG Strong Genetic Variation [80]
CXCL10 TTQOVYA Strong Altered Expression [81]
CYP26A1 TTD7Q0R Strong Altered Expression [82]
DCLK1 TTOHTCY Strong Biomarker [83]
DDX5 TTZKPVC Strong Biomarker [84]
DIABLO TTN74LE Strong Biomarker [85]
DKK2 TTST5KX Strong Altered Expression [86]
DNMT1 TT6S2FE Strong Biomarker [87]
DUSP10 TTF3RJ0 Strong Biomarker [88]
EED TTFNJ4R Strong Biomarker [89]
EGFL7 TT7WD0H Strong Altered Expression [90]
EGFR TTGKNB4 Strong Biomarker [91]
ELAVL1 TTPC9D0 Strong Biomarker [92]
ENPP3 TTD4TKP Strong Biomarker [93]
FDPS TTIKWV4 Strong Altered Expression [94]
FGF19 TTGCH11 Strong Biomarker [95]
FOLR1 TTVC37M Strong Biomarker [96]
FZD7 TTUQMO5 Strong Biomarker [97]
GAP43 TTSGLN5 Strong Biomarker [61]
GCG TT6Y4PN Strong Biomarker [98]
GNAI1 TTL1HWR Strong Altered Expression [99]
GNAI3 TT8QF3W Strong Altered Expression [99]
GRM4 TTICZ1O Strong Biomarker [100]
HDC TTV9GOF Strong Biomarker [101]
HK2 TTK02H8 Strong Biomarker [102]
HOXA5 TTXSVQP Strong Biomarker [103]
HRH1 TTTIBOJ Strong Genetic Variation [23]
ICAM1 TTA1L39 Strong Biomarker [104]
IGFBP1 TTCJTWF Strong Biomarker [61]
IL1RN TT6GSR3 Strong Biomarker [105]
ITGA1 TTPERWV Strong Altered Expression [106]
ITGB6 TTKQSXZ Strong Altered Expression [107]
JAK3 TTT7PJU Strong Therapeutic [108]
JUN TTS7IR5 Strong Biomarker [109]
KCNH2 TTQ6VDM Strong Biomarker [110]
KDM1A TTNR0UQ Strong Biomarker [111]
KDM5B TTCLI75 Strong Biomarker [111]
KIT TTX41N9 Strong Altered Expression [112]
KLF4 TTTI53X Strong Biomarker [113]
LPAR5 TTABCJ6 Strong Altered Expression [114]
LPL TTOF3WZ Strong Biomarker [61]
LTF TTSZDQU Strong Therapeutic [115]
MAOB TTGP7BY Strong Biomarker [61]
MAPKAPK2 TTMUG9D Strong Biomarker [116]
MAT2A TTSMPXQ Strong Altered Expression [117]
METAP2 TTZL0OI Strong Altered Expression [118]
MKI67 TTB4UNG Strong Biomarker [119]
MMP12 TTXZ0KQ Strong Biomarker [61]
MMP7 TTMTWOS Strong Biomarker [120]
MMP9 TT6X50U Strong Biomarker [121]
MSH2 TTCAWRT Strong Altered Expression [122]
MTHFR TTQWOU1 Strong Genetic Variation [123]
MTNR1A TT0WAIE Strong Posttranslational Modification [124]
MTOR TTCJG29 Strong Biomarker [9]
MYB TT8V13P Strong Biomarker [125]
MYC TTNQ5ZP Strong Altered Expression [126]
NFKB1 TTUIZKC Strong Biomarker [127]
NOD1 TTYSRXM Strong Genetic Variation [128]
NOS2 TTF10I9 Strong Biomarker [129]
NOTCH1 TTB1STW Strong Biomarker [3]
NOX4 TTQRBSJ Strong Biomarker [127]
NR0B1 TTTK36V Strong Genetic Variation [130]
NR4A1 TTMXE2Q Strong Altered Expression [131]
OGFR TT6IEYX Strong Biomarker [132]
PCNA TTLG1PD Strong Biomarker [119]
PDE10A TTJW4LU Strong Biomarker [16]
PLA2G2A TTO8QRU Strong Biomarker [133]
PLA2G4A TTT1JVS Strong Biomarker [134]
PLCB1 TTLPGU7 Strong Biomarker [61]
POLB TTA0XPV Strong Genetic Variation [135]
PPARD TT2JWF6 Strong Altered Expression [136]
PRKCD TT7A1BO Strong Biomarker [137]
PRKCZ TTBSN0L Strong Biomarker [138]
PSMB10 TTPNACM Strong Altered Expression [139]
PSMB7 TT49BVC Strong Altered Expression [140]
PSMB9 TTOUSTQ Strong Altered Expression [139]
PTGS2 TTVKILB Strong Altered Expression [141]
PTH1R TTFPD47 Strong Altered Expression [142]
PTK2 TTON5IT Strong Genetic Variation [143]
RNF34 TTEWDK1 Strong Therapeutic [144]
RNF43 TTD91BL Strong Biomarker [145]
RSPO3 TT7HJTF Strong Biomarker [42]
S100A4 TTPR5SX Strong Biomarker [146]
S100A9 TT0TMQG Strong Biomarker [61]
SAA1 TTY0DN9 Strong Biomarker [147]
SDC2 TT5H2F0 Strong Altered Expression [148]
SERPINB3 TT6QLPX Strong Biomarker [149]
SERPINB5 TT1KW50 Strong Biomarker [150]
SGO1 TTBPKGD Strong Biomarker [151]
SLC10A2 TTPI1M5 Strong Biomarker [152]
SLC16A1 TTN1J82 Strong Biomarker [153]
SLC19A1 TT09I7D Strong Biomarker [154]
SLC22A1 TTM5Q4V Strong Biomarker [61]
SLC2A1 TT79TKF Strong Biomarker [155]
SLCO1B3 TTU86P0 Strong Biomarker [156]
SLCO2A1 TTKVTQO Strong Genetic Variation [157]
SPARC TTBQFM7 Strong Biomarker [158]
SPDEF TT2ZUPY Strong Biomarker [159]
SPHK1 TTOHFIY Strong Biomarker [160]
TAGLN TTDRZ9H Strong Biomarker [61]
TCF7L2 TT80QAL Strong Biomarker [161]
TDGF1 TTN7HMG Strong Altered Expression [162]
TIAM1 TTNU6I5 Strong Altered Expression [163]
TMEM97 TT9NXW4 Strong Biomarker [164]
TNFRSF9 TTPW9LJ Strong Biomarker [165]
TYMP TTO0IB8 Strong Biomarker [38]
TYMS TTP1UKZ Strong Biomarker [166]
UGT1A1 TT34ZAF Strong Genetic Variation [167]
UMPS TTAFJUD Strong Biomarker [38]
VANGL1 TT18WJB Strong Biomarker [168]
WDR5 TT7OFWB Strong Altered Expression [169]
WT1 TTZ8UT4 Strong Biomarker [170]
XDH TT7RJY8 Strong Biomarker [171]
YWHAH TTADIOY Strong Altered Expression [172]
ZNF217 TTY3BRA Strong Biomarker [173]
CD55 TT5Z9WY Definitive Biomarker [174]
CXCL2 TTZF0K2 Definitive Altered Expression [175]
FGF18 TT6ICRA Definitive Biomarker [176]
FGFR4 TT1KX2S Definitive Altered Expression [95]
IL32 TTD4G7L Definitive Biomarker [165]
ITGA2 TTSJ542 Definitive Biomarker [177]
KLK6 TTLPF4X Definitive Biomarker [178]
PDE5A TTJ0IQB Definitive Altered Expression [179]
PLAUR TTNOSTX Definitive Biomarker [180]
PTK6 TT6TH8V Definitive Biomarker [181]
PTPN1 TTELIN2 Definitive Altered Expression [182]
SOD2 TT9O4C5 Definitive Biomarker [165]
------------------------------------------------------------------------------------
⏷ Show the Full List of 214 DTT(s)
This Disease Is Related to 5 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
ABCA5 DT195NK Strong Altered Expression [183]
ABCC5 DTYVM24 Strong Altered Expression [184]
ATP7A DT0LT17 Strong Biomarker [185]
SLC26A3 DTN1FMD Strong Altered Expression [186]
SLC5A8 DTE3TAW Strong Posttranslational Modification [187]
------------------------------------------------------------------------------------
This Disease Is Related to 12 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
SAT1 DEMWO83 Limited Biomarker [188]
CES2 DETHCPD moderate Altered Expression [189]
FADS1 DE05S8C moderate Biomarker [190]
ALDH1B1 DEXI4UQ Strong Biomarker [191]
CYP1A1 DE6OQ3W Strong Biomarker [192]
CYP27B1 DE3FYEM Strong Altered Expression [193]
DTYMK DEOTVYU Strong Biomarker [194]
HPGD DEHKSC6 Strong Biomarker [157]
SULT1A1 DEYWLRK Strong Biomarker [61]
UGT1A9 DE85D2P Strong Genetic Variation [167]
UPP1 DEFZWAX Strong Biomarker [195]
HPRT1 DEVXTP5 Definitive Genetic Variation [196]
------------------------------------------------------------------------------------
⏷ Show the Full List of 12 DME(s)
This Disease Is Related to 267 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
ACY1 OT9WU7X3 Limited Altered Expression [197]
BMPR1A OTQOA4ZH Limited Genetic Variation [198]
BRD8 OTIKS3PC Limited Altered Expression [199]
CA8 OT9Y8GA8 Limited Altered Expression [200]
CABLES1 OTMN4XSX Limited Altered Expression [201]
CAST OTBXZZGF Limited Altered Expression [202]
CBFA2T3 OTOJ10S1 Limited Biomarker [203]
CCNH OTKDU3SR Limited Biomarker [9]
CEP55 OTGSG2PA Limited Altered Expression [204]
CKB OTUCKOTT Limited Altered Expression [205]
DMKN OTRIGZMK Limited Biomarker [206]
LGALS4 OTKQCG0H Limited Altered Expression [207]
LPIN1 OTQ75KF2 Limited Genetic Variation [208]
MACIR OTPSW8Y8 Limited Biomarker [9]
MAGI3 OTDJ5QUH Limited Altered Expression [209]
MAP2K4 OTZPZX11 Limited Biomarker [210]
MAP2K6 OTK13JKC Limited Therapeutic [211]
MECOM OTP983W8 Limited Biomarker [212]
MUC2 OT3X4QVX Limited Altered Expression [213]
OXT OT48M72Z Limited Therapeutic [214]
PRKAG2 OTHTAM54 Limited Genetic Variation [215]
PRMT6 OT5V3XIN Limited Biomarker [87]
PRSS2 OTOMVUWL Limited Altered Expression [17]
PRSS58 OTVUH7KR Limited Altered Expression [17]
RHBDD1 OTL5J132 Limited Altered Expression [216]
SESN2 OT889IXY Limited Altered Expression [217]
TLE6 OTB84O0U Limited Altered Expression [218]
TRMT11 OTRK0IOR Limited Biomarker [9]
ACP1 OTJ9CKLU Disputed Genetic Variation [219]
CLDN23 OTN5RV40 Disputed Altered Expression [220]
ENPP7 OTWOBMQ9 Disputed Altered Expression [221]
PLB1 OTZ6TTYV Disputed Altered Expression [27]
ATP2A3 OTFYDEES moderate Altered Expression [222]
CYP2W1 OTXSB1AE moderate Biomarker [223]
ITIH4 OT460OO1 moderate Biomarker [39]
LRG1 OTLD0KWA moderate Biomarker [39]
MCM2 OTGGORIQ moderate Therapeutic [224]
MLH3 OT91PPBI moderate Biomarker [225]
RELA OTUJP9CN moderate Biomarker [226]
SP4 OTWB30IZ moderate Altered Expression [227]
TLE5 OTEH0BFG moderate Altered Expression [228]
A2M OTFTX90K Strong Biomarker [61]
ABCE1 OTH19LOA Strong Biomarker [229]
ACTA2 OTEDLG8E Strong Biomarker [61]
ACTG2 OTRDWUO0 Strong Biomarker [61]
AIFM3 OTSWKCAO Strong Altered Expression [230]
ALDH1A3 OT1C9NKQ Strong Altered Expression [231]
ALG1 OTVXPA9E Strong Posttranslational Modification [124]
AMPD3 OT5SP1KJ Strong Biomarker [232]
ANAPC1 OT2YY35L Strong Biomarker [233]
ANTXR1 OT5W1GPC Strong Biomarker [234]
ASCL2 OT3D62WB Strong Biomarker [61]
ATOH1 OTBZYG2R Strong Altered Expression [213]
ATP5F1E OTMPLAIS Strong Biomarker [235]
AXIN2 OTRMGQNU Strong Genetic Variation [236]
B3GNT8 OTDK2PQD Strong Altered Expression [237]
BAD OT63ERYM Strong Biomarker [238]
BCL2L12 OTS6IFZY Strong Biomarker [239]
BCL9 OTRBIPR4 Strong Altered Expression [240]
BCL9L OTTWI90E Strong Altered Expression [240]
BID OTOSHSHU Strong Biomarker [238]
BIN1 OTK8O0X8 Strong Biomarker [241]
BTRC OT2EZDGR Strong Altered Expression [242]
CALB2 OTSNMCG9 Strong Biomarker [243]
CAV2 OT1FGRQX Strong Altered Expression [244]
CCDC80 OTOZSYEM Strong Biomarker [245]
CCN6 OTRFHQ2Z Strong Altered Expression [246]
CCND2 OTDULQF9 Strong Biomarker [61]
CCNDBP1 OTBWG1M0 Strong Altered Expression [247]
CD109 OTDADBM4 Strong Genetic Variation [248]
CDC16 OTB914M7 Strong Genetic Variation [249]
CDC23 OTC4O83E Strong Genetic Variation [249]
CDK5RAP3 OTC0Q2QS Strong Altered Expression [250]
CDX1 OTOHTMJE Strong Posttranslational Modification [251]
CDX2 OTCG4TSY Strong Biomarker [252]
CEACAM7 OTKFDTZY Strong Biomarker [68]
CELF2 OTLJJ4VT Strong Altered Expression [253]
CEMIP OTK80FYN Strong Biomarker [254]
CHRDL2 OTJU2I5H Strong Altered Expression [255]
CISD3 OT0MM1MW Strong Biomarker [256]
CITED2 OT812TV7 Strong Biomarker [257]
CKM OTME0KO7 Strong Biomarker [61]
CLDN1 OT27KV99 Strong Biomarker [258]
CLDN7 OTNE0XHQ Strong Altered Expression [259]
CLUAP1 OTESP4WL Strong Altered Expression [260]
CNN1 OTVPG39Z Strong Altered Expression [261]
COX3 OTNNGBYJ Strong Altered Expression [262]
CP OTM8JE4Y Strong Biomarker [263]
CRKL OTOYSD1R Strong Altered Expression [264]
DDB2 OTO8HVVB Strong Biomarker [265]
DDX17 OTXRMMBP Strong Biomarker [84]
DDX53 OTHK3EGZ Strong Biomarker [266]
DEFA5 OT95CBQ9 Strong Biomarker [267]
DEFA6 OTDJADMQ Strong Altered Expression [268]
DKK4 OTWCCVF6 Strong Biomarker [269]
DLG1 OTCRZYWT Strong Altered Expression [270]
DMBT1 OTVNU9D9 Strong Biomarker [61]
DMP1 OTBWBWW7 Strong Biomarker [271]
DOK1 OTGVRLW6 Strong Biomarker [272]
DSC2 OTODVH8K Strong Altered Expression [273]
DST OTHZBM4X Strong Biomarker [274]
DSTN OTMXO4YB Strong Biomarker [275]
DUSP2 OTH54FMR Strong Altered Expression [52]
E2F4 OTB3JFH4 Strong Genetic Variation [276]
EDIL3 OTDVVNS0 Strong Biomarker [277]
EFEMP2 OT0I2B4J Strong Altered Expression [278]
EFNB2 OT0DCUOM Strong Altered Expression [279]
EIF3E OTI0WG98 Strong Altered Expression [280]
EIF3I OTE07WND Strong Biomarker [281]
EIF4A1 OTMTBX6N Strong Biomarker [282]
EIF4A2 OT08H03R Strong Biomarker [282]
ENDOV OTX2GXXX Strong Genetic Variation [283]
ESRP1 OTNCS4SL Strong Genetic Variation [284]
EXO1 OTI87RS5 Strong Altered Expression [285]
FABP6 OTIRQWLW Strong Altered Expression [286]
FABP7 OTRE2H4G Strong Biomarker [287]
FBP1 OTQBANEP Strong Biomarker [288]
FERMT1 OT626PBA Strong Altered Expression [289]
FLCN OTVM78XM Strong Genetic Variation [290]
FUT1 OTODG57A Strong Altered Expression [291]
FZD1 OTZATHVS Strong Biomarker [265]
FZD2 OT952ML1 Strong Biomarker [292]
FZD5 OTXFFY56 Strong Biomarker [265]
GALNT12 OTVIBUST Strong Biomarker [293]
GCNT3 OTQ9ALTR Strong Altered Expression [294]
GNAI2 OTTLGRGH Strong Altered Expression [99]
GPR68 OT1NXSMN Strong Biomarker [295]
GPX2 OTXI2NTI Strong Altered Expression [296]
GSTM5 OTMMBFY8 Strong Biomarker [61]
GUCY1A1 OTPTCBUN Strong Biomarker [61]
HAPLN1 OTXWR9TJ Strong Biomarker [232]
HES1 OT8P19W2 Strong Biomarker [3]
HES5 OTW7JEHV Strong Altered Expression [213]
HIP1 OT7AKCFQ Strong Altered Expression [297]
HLTF OTRX2OSF Strong Posttranslational Modification [298]
HOXA3 OTIX5XFB Strong Altered Expression [299]
HSPA2 OTSDET7B Strong Biomarker [61]
HTRA2 OTC7616F Strong Altered Expression [300]
ID3 OTUULW5Z Strong Biomarker [61]
IFITM3 OT2QP8D3 Strong Altered Expression [301]
INPPL1 OTCDAVBQ Strong Biomarker [302]
INSIG2 OTX4VY51 Strong Biomarker [303]
INTS6 OT6GDV46 Strong Altered Expression [304]
ITGA3 OTBCH21D Strong Altered Expression [30]
ITGA7 OTTBTAYW Strong Biomarker [61]
ITIH5 OTP46PZM Strong Altered Expression [305]
KDM2B OTDMCVW7 Strong Biomarker [306]
KHDRBS3 OTUG02U7 Strong Altered Expression [307]
KIF22 OTY6X6BL Strong Genetic Variation [308]
KIFAP3 OT450PAO Strong Biomarker [309]
KPNA2 OTU7FOE6 Strong Altered Expression [310]
LCP1 OTK61F2A Strong Altered Expression [311]
LEF1 OTWS5I5H Strong Altered Expression [130]
LRATD1 OT65IL83 Strong Altered Expression [312]
LSR OTR8Y32X Strong Altered Expression [313]
LY6E OTMG16BZ Strong Altered Expression [314]
MAP7 OTVSSJ33 Strong Altered Expression [315]
MATK OTVOJJLJ Strong Biomarker [316]
MBD4 OTWR9YXE Strong Genetic Variation [317]
MCM5 OTAHLB62 Strong Altered Expression [318]
MEIS1 OTH9DKAD Strong Genetic Variation [319]
MEN1 OTN6U6V0 Strong ModifyingMutation [320]
MEP1A OTY2Z48T Strong Biomarker [61]
METAP1D OT144G80 Strong Altered Expression [321]
MFAP5 OT46VXSG Strong Altered Expression [322]
MGAT5 OTU4DD4G Strong Biomarker [323]
MMP25 OT3BG37V Strong Biomarker [324]
MPZ OTAR2YXH Strong Genetic Variation [130]
MSH6 OT46FP09 Strong Genetic Variation [325]
MT1B OTUA4FFH Strong Posttranslational Modification [124]
MT1E OTXJKU4Y Strong Posttranslational Modification [124]
MT1F OTZVUYG1 Strong Posttranslational Modification [124]
MT1G OTAV1OCR Strong Posttranslational Modification [124]
MT1H OT0MVBM6 Strong Posttranslational Modification [124]
MT1M OTVT8PLU Strong Posttranslational Modification [124]
MT1X OT9AKFVS Strong Posttranslational Modification [124]
NDRG2 OT5L6KD7 Strong Biomarker [61]
NEU3 OTQ5PQOW Strong Altered Expression [326]
NGDN OTBXTCN5 Strong Genetic Variation [327]
NIPBL OTF6OOLU Strong Genetic Variation [328]
NKRF OTUVY0P6 Strong Altered Expression [329]
NLK OT2LETFS Strong Genetic Variation [330]
NME2 OTCYGLHV Strong Altered Expression [331]
NMT1 OT42GQ3D Strong Biomarker [332]
NOL3 OT1K0L0D Strong Biomarker [333]
NOX1 OTZPJQCC Strong Biomarker [127]
NPRL2 OTOB10MO Strong Altered Expression [334]
NRCAM OT80HHQ2 Strong Altered Expression [335]
NUMB OTMB586Q Strong Genetic Variation [336]
NUSAP1 OT85HIJ5 Strong Altered Expression [337]
OBP2A OTBIJ5TI Strong Genetic Variation [308]
OGA OT7ZBWT1 Strong Biomarker [338]
ORC6 OTKQN3KP Strong Biomarker [339]
PALD1 OTLGUM8H Strong Altered Expression [340]
PALLD OTZ2MUJZ Strong Altered Expression [340]
PARP4 OTXBK59G Strong Biomarker [341]
PCBD2 OTXV0ZD0 Strong Biomarker [342]
PCP4 OTM1XXYX Strong Biomarker [61]
PER3 OTVKYVJA Strong Altered Expression [343]
PIGR OT6GLSUL Strong Altered Expression [344]
PLPP3 OTSSF7BK Strong Altered Expression [345]
PMEPA1 OTY8Z9UF Strong Altered Expression [346]
PMP22 OTXWYWCZ Strong Genetic Variation [130]
PODXL OTPNQXF3 Strong Biomarker [347]
POU1F1 OTXT8A5C Strong Biomarker [348]
PRDX3 OTLB2WEU Strong Altered Expression [28]
PRKN OTJBN41W Strong Biomarker [349]
PRMT8 OT3MRK62 Strong Biomarker [350]
PROP1 OT8GF6N8 Strong Altered Expression [348]
PSG2 OT2EIXAI Strong Biomarker [68]
PSME1 OTDHLJWH Strong Altered Expression [139]
PSME2 OTYPP33T Strong Altered Expression [139]
PSMG1 OTZ5I6UM Strong Altered Expression [52]
PVR OT3N91T7 Strong Altered Expression [351]
PXN OTVMMUOF Strong Posttranslational Modification [352]
RB1CC1 OTZK8PFX Strong Genetic Variation [353]
RCOR1 OTREADPC Strong Biomarker [111]
REEP5 OTZU4TJI Strong Biomarker [354]
RFC1 OT3L5PK3 Strong Biomarker [96]
RGCC OTYJMLWM Strong Biomarker [355]
RHOJ OTWI65OA Strong Biomarker [61]
RIOX2 OT2YFPI2 Strong Altered Expression [356]
RNASE1 OTKZ7CO9 Strong Biomarker [357]
RPL29 OTUFIBJL Strong Biomarker [358]
RSPO2 OT3HHXU0 Strong Biomarker [42]
RUVBL1 OTWV19L7 Strong Altered Expression [359]
SASH1 OTQA8BD4 Strong Altered Expression [360]
SCRIB OTW4N3FV Strong Altered Expression [270]
SEPTIN4 OTD16B30 Strong Genetic Variation [128]
SERPINA4 OTBK0GG7 Strong Altered Expression [361]
SERTAD1 OTBHKZQP Strong Biomarker [362]
SH3KBP1 OTIUA60B Strong Biomarker [61]
SHC1 OT1J5IRN Strong Biomarker [363]
SHMT1 OTIINA3J Strong Biomarker [364]
SIM2 OT0QWHK4 Strong Altered Expression [365]
SLC12A9 OTR7VRAK Strong Altered Expression [66]
SNAI1 OTDPYAMC Strong Biomarker [366]
SND1 OTT734JN Strong Altered Expression [367]
SNX1 OTXQSJ1J Strong Biomarker [368]
SNX9 OTLNQ0ZM Strong Altered Expression [246]
SPEN OT37A2MD Strong Biomarker [256]
SRP9 OT4CQTCM Strong Altered Expression [140]
SRPRB OTUUFHQS Strong Altered Expression [369]
STAG1 OT564IX4 Strong Genetic Variation [328]
STRA6 OT2IDF27 Strong Altered Expression [370]
SULF1 OTJCNCO0 Strong Altered Expression [371]
SYMPK OTYAUDXV Strong Genetic Variation [372]
TBX5 OT70PISV Strong Posttranslational Modification [373]
TCF19 OT7NKLF9 Strong Biomarker [61]
TFF2 OTRXB19X Strong Biomarker [374]
TGIF1 OTN9VHAG Strong Altered Expression [375]
TIGAR OTR7NMRJ Strong Altered Expression [376]
TOMM34 OTH6MITE Strong Biomarker [377]
TPD52 OTPKSK43 Strong Altered Expression [74]
TPGS2 OT25O8ME Strong Altered Expression [378]
TPM3 OT5RU5G6 Strong Biomarker [379]
TRAF1 OTTLM5RU Strong Altered Expression [380]
TRIB3 OTG5OS7X Strong Biomarker [381]
TRIP6 OTIPA4ZR Strong Altered Expression [382]
TSGA10 OTIF1O1T Strong Altered Expression [383]
C1GALT1C1 OTRTZUF5 Definitive Altered Expression [384]
CDSN OTQW4HV6 Definitive Altered Expression [385]
DLD OT378CU9 Definitive Biomarker [386]
EOMES OTB9VQFA Definitive Biomarker [387]
EPS8 OTZ6ES6V Definitive Altered Expression [388]
PHLPP1 OTIFXW8D Definitive Biomarker [389]
RETNLB OT9JJQQQ Definitive Biomarker [390]
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⏷ Show the Full List of 267 DOT(s)

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39 The concentrations of EGFR, LRG1, ITIH4, and F5 in serum correlate with the number of colonic adenomas in ApcPirc/+ rats.Cancer Prev Res (Phila). 2014 Nov;7(11):1160-9. doi: 10.1158/1940-6207.CAPR-14-0056. Epub 2014 Sep 8.
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79 Identification of a Tumor Specific, Active-Site Mutation in Casein Kinase 1 by Chemical Proteomics.PLoS One. 2016 Mar 31;11(3):e0152934. doi: 10.1371/journal.pone.0152934. eCollection 2016.
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81 Forced Expression of CXCL10 Prevents Liver Metastasis of Colon Carcinoma Cells by the Recruitment of Natural Killer Cells.Biol Pharm Bull. 2019 Jan 1;42(1):57-65. doi: 10.1248/bpb.b18-00538. Epub 2018 Nov 1.
82 Up-regulation of CYP26A1 in adenomatous polyposis coli-deficient vertebrates via a WNT-dependent mechanism: implications for intestinal cell differentiation and colon tumor development.Cancer Res. 2006 Aug 1;66(15):7571-7. doi: 10.1158/0008-5472.CAN-06-1067.
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91 Ex Vivo and In Vivo Noninvasive Imaging of Epidermal Growth Factor Receptor Inhibition on Colon Tumorigenesis Using Activatable Near-Infrared Fluorescent Probes.Mol Imaging. 2017 Jan-Dec;16:1536012117729044. doi: 10.1177/1536012117729044.
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96 Use of a novel genetic mouse model to investigate the role of folate in colitis-associated colon cancer.J Nutr Biochem. 2009 Aug;20(8):649-55. doi: 10.1016/j.jnutbio.2008.07.001. Epub 2008 Oct 16.
97 Frizzled-7 receptor ectodomain expression in a colon cancer cell line induces morphological change and attenuates tumor growth.Differentiation. 2005 Apr;73(4):142-53. doi: 10.1111/j.1432-0436.2005.00015.x.
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99 GNAI1 and GNAI3 Reduce Colitis-Associated Tumorigenesis in Mice by Blocking IL6 Signaling and Down-regulating Expression of GNAI2.Gastroenterology. 2019 Jun;156(8):2297-2312. doi: 10.1053/j.gastro.2019.02.040. Epub 2019 Mar 2.
100 Metabotropic glutamate receptor 4-mediated 5-Fluorouracil resistance in a human colon cancer cell line.Clin Cancer Res. 2004 Jun 15;10(12 Pt 1):4176-84. doi: 10.1158/1078-0432.CCR-1114-03.
101 Histidine decarboxylase (HDC)-expressing granulocytic myeloid cells induce and recruit Foxp3(+) regulatory T cells in murine colon cancer.Oncoimmunology. 2017 Feb 10;6(3):e1290034. doi: 10.1080/2162402X.2017.1290034. eCollection 2017.
102 Downregulation of the hexokinase II gene sensitizes human colon cancer cells to 5-fluorouracil.Chemotherapy. 2008;54(5):357-63. doi: 10.1159/000153655. Epub 2008 Sep 5.
103 A novel long non-coding RNA from the HOXA6-HOXA5 locus facilitates colon cancer cell growth.BMC Cancer. 2019 Jun 3;19(1):532. doi: 10.1186/s12885-019-5715-0.
104 Colonic epithelial cell expression of ICAM-1 relates to loss of surface continuity: a comparative study of inflammatory bowel disease and colonic neoplasms.Scand J Gastroenterol. 2006 Mar;41(3):318-25. doi: 10.1080/00365520510024241.
105 Polymorphisms in interleukin 1 beta and interleukin 1 receptor antagonist associated with tumor recurrence in stage II colon cancer.Pharmacogenet Genomics. 2009 Feb;19(2):95-102. doi: 10.1097/FPC.0b013e32831a9ad1.
106 Activation of the FAK-src molecular scaffolds and p130Cas-JNK signaling cascades by alpha1-integrins during colon cancer cell invasion.Int J Oncol. 2007 Dec;31(6):1501-8.
107 Integrin expression in colon cancer cells is regulated by the cytoplasmic domain of the beta6 integrin subunit.Int J Cancer. 2002 Jun 1;99(4):529-37. doi: 10.1002/ijc.10397.
108 Role of cytokines and Jak3/Stat3 signaling in the 1,2-dimethylhydrazine dihydrochloride-induced rat model of colon carcinogenesis: early target in the anticancer strategy.Eur J Cancer Prev. 2013 May;22(3):215-28. doi: 10.1097/CEJ.0b013e3283584932.
109 Protective versus promotional effects of white tea and caffeine on PhIP-induced tumorigenesis and beta-catenin expression in the rat.Carcinogenesis. 2008 Apr;29(4):834-9. doi: 10.1093/carcin/bgn051. Epub 2008 Feb 17.
110 [Correlation of HERG K+ channel protein expression to chemosensitivity of tumor cells to doxorubicin and its modulation by erythromycin].Ai Zheng. 2005 Aug;24(8):924-9.
111 Silencing of the DNA mismatch repair gene MLH1 induced by hypoxic stress in a pathway dependent on the histone demethylase LSD1.Cell Rep. 2014 Jul 24;8(2):501-13. doi: 10.1016/j.celrep.2014.06.035. Epub 2014 Jul 17.
112 KIT Signaling Promotes Growth of Colon Xenograft Tumors in Mice and Is Up-Regulated in a Subset of Human Colon Cancers.Gastroenterology. 2015 Sep;149(3):705-17.e2. doi: 10.1053/j.gastro.2015.05.042. Epub 2015 May 28.
113 A miRNA signature for an environmental heterocyclic amine defined by a multi-organ carcinogenicity bioassay in the rat.Arch Toxicol. 2017 Oct;91(10):3415-3425. doi: 10.1007/s00204-017-1945-6. Epub 2017 Mar 13.
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