| 1 |
Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
|
| 2 |
Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007330)
|
| 3 |
Involvement of activation-induced cytidine deaminase in the development of colitis-associated colorectal cancers.J Gastroenterol. 2011 Jan;46 Suppl 1:6-10. doi: 10.1007/s00535-010-0326-1. Epub 2010 Sep 28.
|
| 4 |
Female mice carrying a defective Alox15 gene are protected from experimental colitis via sustained maintenance of the intestinal epithelial barrier function.Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Aug;1863(8):866-880. doi: 10.1016/j.bbalip.2018.04.019. Epub 2018 Apr 24.
|
| 5 |
Colonic Transit Disorder Mediated by Downregulation of Interstitial Cells of Cajal/Anoctamin-1 in Dextran Sodium Sulfate-induced Colitis Mice.J Neurogastroenterol Motil. 2019 Apr 30;25(2):316-331. doi: 10.5056/jnm18173.
|
| 6 |
Evaluation of the effect of liposomes loaded with chlorogenic acid in treatment of 2,4,6-trinitrobenzenesulfonic acid-induced murine colitis.J Physiol Pharmacol. 2019 Apr;70(2). doi: 10.26402/jpp.2019.2.10. Epub 2019 Aug 20.
|
| 7 |
The Importance of Intestinal Eotaxin-1 in Inflammatory Bowel Disease: New Insights and Possible Therapeutic Implications.Dig Dis Sci. 2016 Jul;61(7):1915-24. doi: 10.1007/s10620-016-4047-z. Epub 2016 Feb 13.
|
| 8 |
Expression of chemokine CCL20 in ulcerative colitis.Mol Med Rep. 2012 Dec;6(6):1255-60. doi: 10.3892/mmr.2012.1088. Epub 2012 Sep 20.
|
| 9 |
Colon cancer-associated B2 Escherichia coli colonize gut mucosa and promote cell proliferation.World J Gastroenterol. 2014 Jun 7;20(21):6560-72. doi: 10.3748/wjg.v20.i21.6560.
|
| 10 |
Knockout of ClC-2 reveals critical functions of adherens junctions in colonic homeostasis and tumorigenicity.Am J Physiol Gastrointest Liver Physiol. 2018 Dec 1;315(6):G966-G979. doi: 10.1152/ajpgi.00087.2018. Epub 2018 Oct 4.
|
| 11 |
The Impact of Cannabinoid Receptor 2 Deficiency on Neutrophil Recruitment and Inflammation.DNA Cell Biol. 2019 Oct;38(10):1025-1029. doi: 10.1089/dna.2019.5024. Epub 2019 Sep 18.
|
| 12 |
Protein tyrosine phosphatase SAP-1 protects against colitis through regulation of CEACAM20 in the intestinal epithelium.Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):E4264-71. doi: 10.1073/pnas.1510167112. Epub 2015 Jul 20.
|
| 13 |
Prolyl hydroxylase 2 is dispensable for homeostasis of intestinal epithelium in mice.Acta Biochim Biophys Sin (Shanghai). 2018 Jun 1;50(6):540-546. doi: 10.1093/abbs/gmy037.
|
| 14 |
Haematopoietic prolyl hydroxylase-1 deficiency promotes M2 macrophage polarization and is both necessary and sufficient to protect against experimental colitis.J Pathol. 2017 Mar;241(4):547-558. doi: 10.1002/path.4861. Epub 2017 Jan 27.
|
| 15 |
Western diet induces a shift in microbiota composition enhancing susceptibility to Adherent-Invasive E. coli infection and intestinal inflammation.Sci Rep. 2016 Jan 8;6:19032. doi: 10.1038/srep19032.
|
| 16 |
The regulation and functions of activin and follistatin in inflammation and immunity.Vitam Horm. 2011;85:255-97. doi: 10.1016/B978-0-12-385961-7.00013-5.
|
| 17 |
Characterization of Growth Hormone Resistance in Experimental and Ulcerative Colitis.Int J Mol Sci. 2017 Sep 23;18(10):2046. doi: 10.3390/ijms18102046.
|
| 18 |
TGR5 Protects Against Colitis in Mice, but Vertical Sleeve Gastrectomy Increases Colitis Severity.Obes Surg. 2019 May;29(5):1593-1601. doi: 10.1007/s11695-019-03707-9.
|
| 19 |
Bacterial -glucuronidase alleviates dextran sulfate sodium-induced colitis in mice: A possible crucial new diagnostic and therapeutic target for inflammatory bowel disease.Biochem Biophys Res Commun. 2019 May 28;513(2):426-433. doi: 10.1016/j.bbrc.2019.03.196. Epub 2019 Apr 6.
|
| 20 |
Colonic Inhibition of Phosphatase and Tensin Homolog Increases Colitogenic Bacteria, Causing Development of Colitis in Il10-/- Mice.Inflamm Bowel Dis. 2018 Jul 12;24(8):1718-1732. doi: 10.1093/ibd/izy124.
|
| 21 |
IL-16 induces intestinal inflammation via PepT1 upregulation in a pufferfish model: new insights into the molecular mechanism of inflammatory bowel disease.J Immunol. 2013 Aug 1;191(3):1413-27. doi: 10.4049/jimmunol.1202598. Epub 2013 Jul 1.
|
| 22 |
VPR-254: an inhibitor of ROR-gamma T with potential utility for the treatment of inflammatory bowel disease.Inflammopharmacology. 2020 Apr;28(2):499-511. doi: 10.1007/s10787-019-00643-z. Epub 2019 Sep 23.
|
| 23 |
IL-23 in inflammatory bowel diseases and colon cancer.Cytokine Growth Factor Rev. 2019 Feb;45:1-8. doi: 10.1016/j.cytogfr.2018.12.002. Epub 2018 Dec 12.
|
| 24 |
Loss of Stat6 affects chromatin condensation in intestinal epithelial cells causing diverse outcome in murine models of inflammation-associated and sporadic colon carcinogenesis.Oncogene. 2019 Mar;38(11):1787-1801. doi: 10.1038/s41388-018-0551-2. Epub 2018 Oct 23.
|
| 25 |
MicroRNA-155 promotes the pathogenesis of experimental colitis by repressing SHIP-1 expression.World J Gastroenterol. 2017 Feb 14;23(6):976-985. doi: 10.3748/wjg.v23.i6.976.
|
| 26 |
Inactivation of Interferon Regulatory Factor 1 Causes Susceptibility to Colitis-Associated Colorectal Cancer.Sci Rep. 2019 Dec 11;9(1):18897. doi: 10.1038/s41598-019-55378-2.
|
| 27 |
Collagen-binding integrin alpha1beta1 regulates intestinal inflammation in experimental colitis.J Clin Invest. 2002 Dec;110(12):1773-82. doi: 10.1172/JCI15256.
|
| 28 |
Obesity Modulates Intestinal Intraepithelial T Cell Persistence, CD103 and CCR9 Expression, and Outcome in Dextran Sulfate Sodium-Induced Colitis.J Immunol. 2019 Dec 15;203(12):3427-3435. doi: 10.4049/jimmunol.1900082. Epub 2019 Nov 11.
|
| 29 |
Role of Janus Kinase 3 in Predisposition to Obesity-associated Metabolic Syndrome.J Biol Chem. 2015 Dec 4;290(49):29301-12. doi: 10.1074/jbc.M115.670331. Epub 2015 Oct 8.
|
| 30 |
The Plasma Kallikrein-Kininogen Pathway Is Critical in the Pathogenesis of Colitis in Mice.Front Immunol. 2018 Feb 6;9:21. doi: 10.3389/fimmu.2018.00021. eCollection 2018.
|
| 31 |
Production of a Functional Factor, p40, by Lactobacillus rhamnosus GG Is Promoted by Intestinal Epithelial Cell-Secreted Extracellular Vesicles.Infect Immun. 2019 Jun 20;87(7):e00113-19. doi: 10.1128/IAI.00113-19. Print 2019 Jul.
|
| 32 |
NOX1-derived ROS drive the expression of Lipocalin-2 in colonic epithelial cells in inflammatory conditions.Mucosal Immunol. 2019 Jan;12(1):117-131. doi: 10.1038/s41385-018-0086-4. Epub 2018 Oct 2.
|
| 33 |
An increase in LRRK2 suppresses autophagy and enhances Dectin-1-induced immunity in a mouse model of colitis.Sci Transl Med. 2018 Jun 6;10(444):eaan8162. doi: 10.1126/scitranslmed.aan8162.
|
| 34 |
ABIN2 Function Is Required To Suppress DSS-Induced Colitis by a Tpl2-Independent Mechanism.J Immunol. 2018 Dec 1;201(11):3373-3382. doi: 10.4049/jimmunol.1700614. Epub 2018 Oct 24.
|
| 35 |
Lack of MMP10 exacerbates experimental colitis and promotes development of inflammation-associated colonic dysplasia.Lab Invest. 2012 Dec;92(12):1749-59. doi: 10.1038/labinvest.2012.141. Epub 2012 Oct 8.
|
| 36 |
Hydroalcoholic extract of Brazilian red propolis exerts protective effects on acetic acid-induced ulcerative colitis in a rodent model.Biomed Pharmacother. 2017 Jan;85:687-696. doi: 10.1016/j.biopha.2016.11.080. Epub 2016 Dec 7.
|
| 37 |
Secoisolariciresinol diglucoside suppresses Dextran sulfate sodium salt-induced colitis through inhibiting NLRP1 inflammasome.Int Immunopharmacol. 2020 Jan;78:105931. doi: 10.1016/j.intimp.2019.105931. Epub 2019 Dec 5.
|
| 38 |
RICK/RIP2 is a NOD2-independent nodal point of gut inflammation.Int Immunol. 2019 Sep 18;31(10):669-683. doi: 10.1093/intimm/dxz045.
|
| 39 |
ErbB4 signaling stimulates pro-inflammatory macrophage apoptosis and limits colonic inflammation.Cell Death Dis. 2017 Feb 23;8(2):e2622. doi: 10.1038/cddis.2017.42.
|
| 40 |
Neurotensin Promotes the Development of Colitis and Intestinal Angiogenesis via Hif-1-miR-210 Signaling.J Immunol. 2016 May 15;196(10):4311-21. doi: 10.4049/jimmunol.1501443. Epub 2016 Apr 13.
|
| 41 |
Group X Secreted Phospholipase A2 Releases 3 Polyunsaturated Fatty Acids, Suppresses Colitis, and Promotes Sperm Fertility.J Biol Chem. 2016 Mar 25;291(13):6895-911. doi: 10.1074/jbc.M116.715672. Epub 2016 Jan 31.
|
| 42 |
RSK2 is required for TRAF6 phosphorylation-mediated colon inflammation.Oncogene. 2018 Jun;37(26):3501-3513. doi: 10.1038/s41388-018-0167-6. Epub 2018 Mar 22.
|
| 43 |
RAMP1 suppresses mucosal injury from dextran sodium sulfate-induced colitis in mice.J Gastroenterol Hepatol. 2017 Apr;32(4):809-818. doi: 10.1111/jgh.13505.
|
| 44 |
Cell surface-anchored syndecan-1 ameliorates intestinal inflammation and neutrophil transmigration in ulcerative colitis.J Cell Mol Med. 2017 Jan;21(1):13-25. doi: 10.1111/jcmm.12934. Epub 2016 Aug 25.
|
| 45 |
Cancer-induced inflammation and inflammation-induced cancer in colon: a role for S1P lyase.Oncogene. 2019 Jun;38(24):4788-4803. doi: 10.1038/s41388-019-0758-x. Epub 2019 Feb 28.
|
| 46 |
Salidroside attenuates dextran sulfate sodium-induced colitis in mice via SIRT1/FoxOs signaling pathway.Eur J Pharmacol. 2019 Oct 15;861:172591. doi: 10.1016/j.ejphar.2019.172591. Epub 2019 Aug 8.
|
| 47 |
Haploinsufficiency of Trp53 dramatically extends the lifespan of Sirt6-deficient mice.Elife. 2018 Feb 23;7:e32127. doi: 10.7554/eLife.32127.
|
| 48 |
Overexpression of CD98 in intestinal epithelium dysregulates miRNAs and their targeted proteins along the ileal villus-crypt axis.Sci Rep. 2018 Nov 1;8(1):16220. doi: 10.1038/s41598-018-34474-9.
|
| 49 |
Uncoupling of Carbonic Anhydrase from Na-H exchanger-1 in Experimental Colitis: A Possible Mechanistic Link with Na-H Exchanger.Biomolecules. 2019 Nov 5;9(11):700. doi: 10.3390/biom9110700.
|
| 50 |
Microbial dysbiosis associated with impaired intestinal Na(+)/H(+) exchange accelerates and exacerbates colitis in ex-germ free mice.Mucosal Immunol. 2018 Sep;11(5):1329-1341. doi: 10.1038/s41385-018-0035-2. Epub 2018 Jun 6.
|
| 51 |
NPD-0414-2 and NPD-0414-24, Two Chemical Entities Designed as Aryl Hydrocarbon Receptor (AhR) Ligands, Inhibit Gut Inflammatory Signals.Front Pharmacol. 2019 Apr 12;10:380. doi: 10.3389/fphar.2019.00380. eCollection 2019.
|
| 52 |
Matriptase protects against experimental colitis and promotes intestinal barrier recovery.Inflamm Bowel Dis. 2012 Jul;18(7):1303-14. doi: 10.1002/ibd.21930. Epub 2011 Nov 13.
|
| 53 |
Interleukin 21 collaborates with interferon- for the optimal expression of interferon-stimulated genes and enhances protection against enteric microbial infection.PLoS Pathog. 2019 Feb 28;15(2):e1007614. doi: 10.1371/journal.ppat.1007614. eCollection 2019 Feb.
|
| 54 |
Electroacupuncture relieved visceral and referred hindpaw hypersensitivity in colitis rats by inhibiting tyrosine hydroxylase expression in the sixth lumbar dorsal root ganglia.Neuropeptides. 2019 Oct;77:101957. doi: 10.1016/j.npep.2019.101957. Epub 2019 Jul 23.
|
| 55 |
IL-36 from Skin-Resident Cells Plays an Important Role in the Pathogenesis of Imiquimod-Induced Psoriasiform Dermatitis by Forming a Local Autoamplification Loop.J Immunol. 2018 Jul 1;201(1):167-182. doi: 10.4049/jimmunol.1701157. Epub 2018 May 23.
|
| 56 |
Protective Role for TWEAK/Fn14 in Regulating Acute Intestinal Inflammation and Colitis-Associated Tumorigenesis.Cancer Res. 2016 Nov 15;76(22):6533-6542. doi: 10.1158/0008-5472.CAN-16-0400. Epub 2016 Sep 9.
|
| 57 |
Activation of DR3 signaling causes loss of ILC3s and exacerbates intestinal inflammation.Nat Commun. 2019 Jul 29;10(1):3371. doi: 10.1038/s41467-019-11304-8.
|
| 58 |
The Tumor Necrosis Factor Superfamily Members TNFSF14 (LIGHT), Lymphotoxin and Lymphotoxin Receptor Interact to Regulate Intestinal Inflammation.Front Immunol. 2018 Nov 22;9:2585. doi: 10.3389/fimmu.2018.02585. eCollection 2018.
|
| 59 |
Extracellular vesicles containing miR-146a attenuate experimental colitis by targeting TRAF6 and IRAK1.Int Immunopharmacol. 2019 Mar;68:204-212. doi: 10.1016/j.intimp.2018.12.043. Epub 2019 Jan 15.
|
| 60 |
TLR4 mediates upregulation and sensitization of TRPV1 in primary afferent neurons in 2,4,6-trinitrobenzene sulfate-induced colitis.Mol Pain. 2019 Jan-Dec;15:1744806919830018. doi: 10.1177/1744806919830018.
|
| 61 |
Unique role of junctional adhesion molecule-a in maintaining mucosal homeostasis in inflammatory bowel disease.Gastroenterology. 2008 Jul;135(1):173-84. doi: 10.1053/j.gastro.2008.04.002. Epub 2008 Apr 11.
|
| 62 |
FGL2 regulates IKK/NF-B signaling in intestinal epithelial cells and lamina propria dendritic cells to attenuate dextran sulfate sodium-induced colitis.Mol Immunol. 2020 Jan;117:84-93. doi: 10.1016/j.molimm.2019.11.001. Epub 2019 Nov 16.
|
| 63 |
Interleukin-27 Is a Potential Rescue Therapy for Acute Severe Colitis Through Interleukin-10-Dependent, T-Cell-Independent Attenuation of Colonic Mucosal Innate Immune Responses.Inflamm Bowel Dis. 2017 Nov;23(11):1983-1995. doi: 10.1097/MIB.0000000000001274.
|
| 64 |
Suppression of IL-17F, but not of IL-17A, provides protection against colitis by inducing T(reg) cells through modification of the intestinal microbiota.Nat Immunol. 2018 Jul;19(7):755-765. doi: 10.1038/s41590-018-0134-y. Epub 2018 Jun 18.
|
| 65 |
Integrin-Linked Kinase Expression in Myeloid Cells Promotes Inflammatory Signaling during Experimental Colitis.J Immunol. 2017 Aug 9:ji1700125. doi: 10.4049/jimmunol.1700125. Online ahead of print.
|
| 66 |
Patchouli alcohol activates PXR and suppresses the NF-B-mediated intestinal inflammatory.J Ethnopharmacol. 2020 Feb 10;248:112302. doi: 10.1016/j.jep.2019.112302. Epub 2019 Oct 12.
|
| 67 |
Nrf2 is not required for epithelial prohibitin-dependent attenuation of experimental colitis.Am J Physiol Gastrointest Liver Physiol. 2013 May 15;304(10):G885-96. doi: 10.1152/ajpgi.00327.2012. Epub 2013 Mar 14.
|
| 68 |
Heligmosomoides polygyrus bakeri Infection Decreases Smad7 Expression in Intestinal CD4(+) T Cells, Which Allows TGF- to Induce IL-10-Producing Regulatory T Cells That Block Colitis.J Immunol. 2019 Apr 15;202(8):2473-2481. doi: 10.4049/jimmunol.1801392. Epub 2019 Mar 8.
|
| 69 |
Microbiota-Induced TNF-like Ligand 1A Drives Group 3 Innate Lymphoid Cell-Mediated Barrier Protection and Intestinal T Cell Activation during Colitis.Immunity. 2018 Dec 18;49(6):1077-1089.e5. doi: 10.1016/j.immuni.2018.10.014. Epub 2018 Dec 11.
|
| 70 |
Short Thymic Stromal Lymphopoietin Attenuates Toluene Diisocyanate-induced Airway Inflammation and Inhibits High Mobility Group Box 1-Receptor for Advanced Glycation End Products and Long Thymic Stromal Lymphopoietin Expression.Toxicol Sci. 2017 Jun 1;157(2):276-290. doi: 10.1093/toxsci/kfx043.
|
| 71 |
Imbalance of autophagy and apoptosis in intestinal epithelium lacking the vitamin D receptor.FASEB J. 2019 Nov;33(11):11845-11856. doi: 10.1096/fj.201900727R. Epub 2019 Jul 30.
|
| 72 |
Inflammatory neutrophils secrete annexin 1 during experimentally induced colitis in rats.Dig Dis Sci. 1999 Jul;44(7):1448-57. doi: 10.1023/a:1026668206020.
|
| 73 |
BMP signaling in rats with TNBS-induced colitis following BMP7 therapy.Am J Physiol Gastrointest Liver Physiol. 2012 May 15;302(10):G1151-62. doi: 10.1152/ajpgi.00244.2011. Epub 2012 Feb 23.
|
| 74 |
Anti-inflammatory effect of acute stress on experimental colitis is mediated by cholecystokinin-B receptors.Life Sci. 2004 May 21;75(1):77-91. doi: 10.1016/j.lfs.2003.12.009.
|
| 75 |
Treatment with Met-RANTES decreases bacterial translocation in experimental colitis.Am J Surg. 2006 Jan;191(1):77-83. doi: 10.1016/j.amjsurg.2005.10.005.
|
| 76 |
Glutamine inhibits over-expression of pro-inflammatory genes and down-regulates the nuclear factor kappaB pathway in an experimental model of colitis in the rat.Toxicology. 2007 Jul 17;236(3):217-26. doi: 10.1016/j.tox.2007.04.012. Epub 2007 Apr 27.
|
| 77 |
Alterations in Enterohepatic Fgf15 Signaling and Changes in Bile Acid Composition Depend on Localization of Murine Intestinal Inflammation.Inflamm Bowel Dis. 2016 Oct;22(10):2382-9. doi: 10.1097/MIB.0000000000000879.
|
| 78 |
Ghrelin ameliorates colonic inflammation. Role of nitric oxide and sensory nerves.J Physiol Pharmacol. 2009 Jun;60(2):41-7.
|
| 79 |
Dietary -linolenic acid-rich formula reduces adhesion molecules in rats with experimental colitis.Nutrition. 2012 Jul;28(7-8):799-802. doi: 10.1016/j.nut.2011.10.008. Epub 2012 Jan 20.
|
| 80 |
Morphological and biochemical alterations in the jejunum following iodoacetamide-induced colitis in rats.Can J Physiol Pharmacol. 2006 Nov;84(11):1191-203. doi: 10.1139/y06-069.
|
| 81 |
Inactivation of JNK2 as carcinogenic factor in colitis-associated and sporadic colorectal carcinogenesis.Carcinogenesis. 2017 May 1;38(5):559-569. doi: 10.1093/carcin/bgx032.
|
| 82 |
Colitis elicits differential changes in the expression levels of receptor tyrosine kinase TrkA and TrkB in colonic afferent neurons: a possible involvement of axonal transport.Pain. 2010 Oct;151(1):117-127. doi: 10.1016/j.pain.2010.06.029. Epub 2010 Jul 16.
|
| 83 |
Spatial and temporal expression of tachykinins and NK1- and NK2-receptor gene during TNB induced colitis in rats.Neuropeptides. 2008 Oct-Dec;42(5-6):663-70. doi: 10.1016/j.npep.2008.07.001. Epub 2008 Aug 19.
|
| 84 |
cDNA cloning of rat pS2 peptide and expression of trefoil peptides in acetic acid-induced colitis.Biochem J. 1996 Sep 15;318 ( Pt 3)(Pt 3):939-44. doi: 10.1042/bj3180939.
|
| 85 |
Dietary Chitin Particles Called Mimetic Fungi Ameliorate Colitis in Toll-Like Receptor 2/CD14- and Sex-Dependent Manners.Infect Immun. 2019 Apr 23;87(5):e00006-19. doi: 10.1128/IAI.00006-19. Print 2019 Mar.
|
| 86 |
Interleukin-33 delays recovery of mucosal inflammation via downregulation of homeostatic ABCG5/8 in the colon.Lab Invest. 2020 Mar;100(3):491-502. doi: 10.1038/s41374-019-0329-3. Epub 2019 Oct 22.
|
| 87 |
The Adipokine Metrnl Ameliorates Chronic Colitis in Il-10-/- Mice by Attenuating Mesenteric Adipose Tissue Lesions During Spontaneous Colitis.J Crohns Colitis. 2019 Jul 25;13(7):931-941. doi: 10.1093/ecco-jcc/jjz001.
|
| 88 |
Adiponectin confers protection from acute colitis and restricts a B cell immune response.J Biol Chem. 2017 Apr 21;292(16):6569-6582. doi: 10.1074/jbc.M115.712646. Epub 2017 Mar 3.
|
| 89 |
MicroRNA-206 is involved in the pathogenesis of ulcerative colitis via regulation of adenosine A3 receptor.Oncotarget. 2017 Jan 3;8(1):705-721. doi: 10.18632/oncotarget.13525.
|
| 90 |
The beta3-adrenoceptor agonist SR58611A ameliorates experimental colitis in rats.Neurogastroenterol Motil. 2008 Sep;20(9):1030-41. doi: 10.1111/j.1365-2982.2008.01138.x. Epub 2008 May 15.
|
| 91 |
Aryl hydrocarbon receptor activation alleviates dextran sodium sulfate-induced colitis through enhancing the differentiation of goblet cells.Biochem Biophys Res Commun. 2019 Jun 18;514(1):180-186. doi: 10.1016/j.bbrc.2019.04.136. Epub 2019 Apr 24.
|
| 92 |
Tissue Non-specific Alkaline Phosphatase Expression is Needed for the Full Stimulation of T Cells and T Cell-Dependent Colitis.J Crohns Colitis. 2017 Jul 1;11(7):857-870. doi: 10.1093/ecco-jcc/jjw222.
|
| 93 |
Transient receptor potential vanilloid 1 and transient receptor potential ankyrin 1 contribute to the progression of colonic inflammation in dextran sulfate sodium-induced colitis in mice: Links to calcitonin gene-related peptide and substance P.J Pharmacol Sci. 2018 Mar;136(3):121-132. doi: 10.1016/j.jphs.2017.12.012. Epub 2018 Feb 8.
|
| 94 |
Epigenetic regulation of WNT signaling pathway genes in inflammatory bowel disease (IBD) associated neoplasia.J Gastrointest Surg. 2008 Oct;12(10):1745-53. doi: 10.1007/s11605-008-0633-5. Epub 2008 Aug 21.
|
| 95 |
Adipokine apelin ameliorates chronic colitis in Il-10(-/-) mice by promoting intestinal lymphatic functions.Biochem Pharmacol. 2018 Feb;148:202-212. doi: 10.1016/j.bcp.2018.01.011. Epub 2018 Jan 5.
|
| 96 |
Apolipoprotein A-IV is an independent predictor of disease activity in patients with inflammatory bowel disease.Inflamm Bowel Dis. 2007 Apr;13(4):391-7. doi: 10.1002/ibd.20078.
|
| 97 |
Aquaporin 9 Contributes to the Maturation Process and Inflammatory Cytokine Secretion of Murine Dendritic Cells.Front Immunol. 2018 Oct 16;9:2355. doi: 10.3389/fimmu.2018.02355. eCollection 2018.
|
| 98 |
COX-1/PGE(2)/EP4 alleviates mucosal injury by upregulating -arr1-mediated Akt signaling in colitis.Sci Rep. 2017 Apr 21;7(1):1055. doi: 10.1038/s41598-017-01169-6.
|
| 99 |
-Arrestin2 encourages inflammation-induced epithelial apoptosis through ER stress/PUMA in colitis.Mucosal Immunol. 2015 May;8(3):683-95. doi: 10.1038/mi.2014.104. Epub 2014 Nov 5.
|
| 100 |
Upregulation of ASAP3 contributes to colorectal carcinogenesis and indicates poor survival outcome.Cancer Sci. 2017 Aug;108(8):1544-1555. doi: 10.1111/cas.13281. Epub 2017 Jun 14.
|
| 101 |
Transcriptional factor ATF3 protects against colitis by regulating follicular helper T cells in Peyer's patches.Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6286-6291. doi: 10.1073/pnas.1818164116. Epub 2019 Mar 12.
|
| 102 |
BTB and CNC homolog 1 (Bach1) deficiency ameliorates TNBS colitis in mice: role of M2 macrophages and heme oxygenase-1.Inflamm Bowel Dis. 2013 Mar-Apr;19(4):740-53. doi: 10.1097/MIB.0b013e3182802968.
|
| 103 |
GART mediates the renewal of intestinal epithelial barrier via p38/p53/PUMA cascade in colitis.Apoptosis. 2016 Dec;21(12):1386-1397. doi: 10.1007/s10495-016-1301-y.
|
| 104 |
MicroRNA 301A Promotes Intestinal Inflammation and Colitis-Associated Cancer Development by Inhibiting BTG1. Gastroenterology. 2017 May;152(6):1434-1448.e15.
|
| 105 |
Blockade of complement activation product C5a activity using specific antibody attenuates intestinal damage in trinitrobenzene sulfonic acid induced model of colitis.Lab Invest. 2011 Mar;91(3):472-83. doi: 10.1038/labinvest.2010.183. Epub 2010 Nov 22.
|
| 106 |
Calpain-2 Inhibitor Therapy Reduces Murine Colitis and Colitis-associated Cancer.Inflamm Bowel Dis. 2015 Sep;21(9):2005-15. doi: 10.1097/MIB.0000000000000471.
|
| 107 |
Targeting eotaxin-1 and CCR3 receptor alleviates enteric neuropathy and colonic dysfunction in TNBS-induced colitis in guinea pigs.Neurogastroenterol Motil. 2018 Nov;30(11):e13391. doi: 10.1111/nmo.13391. Epub 2018 Jul 3.
|
| 108 |
Anti-mouse CD52 Treatment Ameliorates Colitis through Suppressing Th1/17 Mediated Inflammation and Promoting Tregs Differentiation in IL-10 Deficient Mice.Biol Pharm Bull. 2018 Sep 1;41(9):1423-1429. doi: 10.1248/bpb.b18-00261. Epub 2018 Jun 13.
|
| 109 |
Difference in Ulex europaeus agglutinin I-binding activity of decay-accelerating factor detected in the stools of patients with colorectal cancer and ulcerative colitis.J Lab Clin Med. 2004 Mar;143(3):169-74. doi: 10.1016/j.lab.2003.11.005.
|
| 110 |
Murine CD83-positive T cells mediate suppressor functions in vitro and in vivo.Immunobiology. 2015 Feb;220(2):270-9. doi: 10.1016/j.imbio.2014.08.005. Epub 2014 Aug 10.
|
| 111 |
Knockout of Ceramide Kinase Aggravates Pathological and Lethal Responses in Mice with Experimental Colitis.Biol Pharm Bull. 2018;41(5):797-805. doi: 10.1248/bpb.b18-00051.
|
| 112 |
Pivotal Role of Carbohydrate Sulfotransferase 15 in Fibrosis and Mucosal Healing in Mouse Colitis.PLoS One. 2016 Jul 13;11(7):e0158967. doi: 10.1371/journal.pone.0158967. eCollection 2016.
|
| 113 |
Increased expression of the tight junction molecule claudin-18 A1 in both experimental colitis and ulcerative colitis.Inflamm Bowel Dis. 2008 Dec;14(12):1652-9. doi: 10.1002/ibd.20695.
|
| 114 |
Glutathione peroxidase 2 and aquaporin 8 as new markers for colonic inflammation in experimental colitis and inflammatory bowel diseases: an important role for H2O2?.Eur J Gastroenterol Hepatol. 2008 Jun;20(6):555-60. doi: 10.1097/MEG.0b013e3282f45751.
|
| 115 |
Activation of corticotropin-releasing factor receptor 1 aggravates dextran sodium sulphate-induced colitis in mice by promoting M1 macrophage polarization.Mol Med Rep. 2018 Jan;17(1):234-242. doi: 10.3892/mmr.2017.7909. Epub 2017 Oct 26.
|
| 116 |
Mucosa repair mechanisms of Tong-Xie-Yao-Fang mediated by CRH-R2 in murine, dextran sulfate sodium-induced colitis.World J Gastroenterol. 2018 Apr 28;24(16):1766-1778. doi: 10.3748/wjg.v24.i16.1766.
|
| 117 |
Effect of a probiotic beverage consumption (Enterococcus faecium CRL 183 and Bifidobacterium longum ATCC 15707) in rats with chemically induced colitis.PLoS One. 2017 Apr 24;12(4):e0175935. doi: 10.1371/journal.pone.0175935. eCollection 2017.
|
| 118 |
Beneficial effects of dual TORC1/2 inhibition on chronic experimental colitis.Int Immunopharmacol. 2019 May;70:88-100. doi: 10.1016/j.intimp.2019.02.022. Epub 2019 Feb 20.
|
| 119 |
Granulocyte-colony-stimulating factor (G-CSF) signaling in spinal microglia drives visceral sensitization following colitis.Proc Natl Acad Sci U S A. 2017 Oct 17;114(42):11235-11240. doi: 10.1073/pnas.1706053114. Epub 2017 Oct 2.
|
| 120 |
Preparation of Chondroitin Sulfate-Glycyl-Prednisolone Conjugate Nanogel and Its Efficacy in Rats with Ulcerative Colitis.Biol Pharm Bull. 2019;42(7):1155-1163. doi: 10.1248/bpb.b19-00020.
|
| 121 |
Preventive Effect of Cardiotrophin-1 Administration before DSS-Induced Ulcerative Colitis in Mice.J Clin Med. 2019 Dec 1;8(12):2086. doi: 10.3390/jcm8122086.
|
| 122 |
Negative regulation of DSS-induced experimental colitis by PILR.Int Immunol. 2015 Jun;27(6):307-14. doi: 10.1093/intimm/dxv004. Epub 2015 Feb 20.
|
| 123 |
Dclk1 in tuft cells promotes inflammation-driven epithelial restitution and mitigates chronic colitis.Cell Death Differ. 2019 Sep;26(9):1656-1669. doi: 10.1038/s41418-018-0237-x. Epub 2018 Nov 26.
|
| 124 |
DUSP10 regulates intestinal epithelial cell growth and colorectal tumorigenesis. Oncogene. 2016 Jan 14;35(2):206-17.
|
| 125 |
Autotaxin determines colitis severity in mice and is secreted by B cells in the colon.FASEB J. 2019 Mar;33(3):3623-3635. doi: 10.1096/fj.201801415RR. Epub 2018 Nov 27.
|
| 126 |
Mucosal Profiling of Pediatric-Onset Colitis and IBD Reveals Common Pathogenics and Therapeutic Pathways.Cell. 2019 Nov 14;179(5):1160-1176.e24. doi: 10.1016/j.cell.2019.10.027.
|
| 127 |
ERAP1 deficient mice have reduced Type 1 regulatory T cells and develop skeletal and intestinal features of Ankylosing Spondylitis.Sci Rep. 2018 Aug 20;8(1):12464. doi: 10.1038/s41598-018-30159-5.
|
| 128 |
Acute experimental colitis and human chronic inflammatory diseases share expression of inflammation-related genes with conserved Ets2 binding sites.Inflamm Bowel Dis. 2009 Feb;15(2):224-35. doi: 10.1002/ibd.20747.
|
| 129 |
The RAGE signaling pathway is involved in intestinal inflammation and represents a promising therapeutic target for Inflammatory Bowel Diseases.Mucosal Immunol. 2019 Mar;12(2):468-478. doi: 10.1038/s41385-018-0119-z. Epub 2018 Dec 12.
|
| 130 |
G protein-coupled receptor 40 activation ameliorates dextran sulfatesodium-induced colitis in mice via the upregulation of glucagon-likepeptide-2.J Pharmacol Sci. 2019 Jun;140(2):144-152. doi: 10.1016/j.jphs.2019.05.003. Epub 2019 May 22.
|
| 131 |
GPR120, a potential therapeutic target for experimental colitis in IL-10 deficient mice.Oncotarget. 2017 Jan 31;8(5):8397-8405. doi: 10.18632/oncotarget.14210.
|
| 132 |
Formyl peptide receptor 1 signalling promotes experimental colitis in mice.Pharmacol Res. 2019 Mar;141:591-601. doi: 10.1016/j.phrs.2019.01.041. Epub 2019 Jan 31.
|
| 133 |
Formyl peptide receptor 2 orchestrates mucosal protection against Citrobacter rodentium infection.Virulence. 2019 Dec;10(1):610-624. doi: 10.1080/21505594.2019.1635417.
|
| 134 |
The MHC Class II Immunopeptidome of Lymph Nodes in Health and in Chemically Induced Colitis.J Immunol. 2017 Feb 1;198(3):1357-1364. doi: 10.4049/jimmunol.1601157. Epub 2016 Dec 23.
|
| 135 |
Association of Ulcerative Colitis with FUT2 and FUT3 Polymorphisms in Patients from Southeast China.PLoS One. 2016 Jan 14;11(1):e0146557. doi: 10.1371/journal.pone.0146557. eCollection 2016.
|
| 136 |
Glugacon-like peptide-2: broad receptor expression, limited therapeutic effect on intestinal inflammation and novel role in liver regeneration.Am J Physiol Gastrointest Liver Physiol. 2014 Aug 1;307(3):G274-85. doi: 10.1152/ajpgi.00389.2012. Epub 2014 May 29.
|
| 137 |
GNAI1 and GNAI3 Reduce Colitis-Associated Tumorigenesis in Mice by Blocking IL6 Signaling and Down-regulating Expression of GNAI2.Gastroenterology. 2019 Jun;156(8):2297-2312. doi: 10.1053/j.gastro.2019.02.040. Epub 2019 Mar 2.
|
| 138 |
The EBI2-oxysterol axis promotes the development of intestinal lymphoid structures and colitis.Mucosal Immunol. 2019 May;12(3):733-745. doi: 10.1038/s41385-019-0140-x. Epub 2019 Feb 11.
|
| 139 |
GSTO1-1 plays a pro-inflammatory role in models of inflammation, colitis and obesity.Sci Rep. 2017 Dec 19;7(1):17832. doi: 10.1038/s41598-017-17861-6.
|
| 140 |
The guanylate cyclase-C signaling pathway is down-regulated in inflammatory bowel disease.Scand J Gastroenterol. 2015;50(10):1241-52. doi: 10.3109/00365521.2015.1038849. Epub 2015 May 15.
|
| 141 |
Effect of Niacin on Inflammation and Angiogenesis in a Murine Model of Ulcerative Colitis.Sci Rep. 2017 Aug 2;7(1):7139. doi: 10.1038/s41598-017-07280-y.
|
| 142 |
15-Deoxy-(12,14)-prostaglandin J(2) ameliorates dextran sulfate sodium-induced colitis in mice through heme oxygenase-1 induction.Arch Biochem Biophys. 2019 Nov 30;677:108183. doi: 10.1016/j.abb.2019.108183. Epub 2019 Nov 5.
|
| 143 |
Blueberry husks and probiotics attenuate colorectal inflammation and oncogenesis, and liver injuries in rats exposed to cycling DSS-treatment.PLoS One. 2012;7(3):e33510. doi: 10.1371/journal.pone.0033510. Epub 2012 Mar 23.
|
| 144 |
Serotonin 5-HT7 receptor is critically involved in acute and chronic inflammation of the gastrointestinal tract.Inflamm Bowel Dis. 2014 Sep;20(9):1516-29. doi: 10.1097/MIB.0000000000000150.
|
| 145 |
Colon Immune-Related Adverse Events: Anti-CTLA-4 and Anti-PD-1 Blockade Induce Distinct Immunopathological Entities.J Crohns Colitis. 2017 Oct 1;11(10):1238-1246. doi: 10.1093/ecco-jcc/jjx081.
|
| 146 |
Type I interferon signaling restrains IL-10R+ colonic macrophages and dendritic cells and leads to more severe Salmonella colitis.PLoS One. 2017 Nov 30;12(11):e0188600. doi: 10.1371/journal.pone.0188600. eCollection 2017.
|
| 147 |
IFN- drives inflammatory bowel disease pathogenesis through VE-cadherin-directed vascular barrier disruption.J Clin Invest. 2019 Nov 1;129(11):4691-4707. doi: 10.1172/JCI124884.
|
| 148 |
Attenuation of NF-B in Intestinal Epithelial Cells Is Sufficient to Mitigate the Bone Loss Comorbidity of Experimental Mouse Colitis.J Bone Miner Res. 2019 Oct;34(10):1880-1893. doi: 10.1002/jbmr.3759. Epub 2019 Jul 25.
|
| 149 |
IBD: of mice and men-shedding new light on IL-13 activity in IBD.Nat Rev Gastroenterol Hepatol. 2011 Mar;8(3):128-9. doi: 10.1038/nrgastro.2011.17. Epub 2011 Feb 8.
|
| 150 |
Interleukin-19 contributes as a protective factor in experimental Th2-mediated colitis. Naunyn Schmiedebergs Arch Pharmacol. 2017 Mar;390(3):261-268.
|
| 151 |
IL-36R signalling activates intestinal epithelial cells and fibroblasts and promotes mucosal healing in vivo.Gut. 2017 May;66(5):823-838. doi: 10.1136/gutjnl-2015-310374. Epub 2016 Jan 18.
|
| 152 |
Suppression of inflammation and acquired immunity by IL-37.Immunol Rev. 2018 Jan;281(1):179-190. doi: 10.1111/imr.12605.
|
| 153 |
Interleukin 4 induces rapid mucin transport, increases mucus thickness and quality and decreases colitis and Citrobacter rodentium in contact with epithelial cells.Virulence. 2019 Dec;10(1):97-117. doi: 10.1080/21505594.2019.1573050.
|
| 154 |
Expression of IRAK? is associated with colitisassociated tumorigenesis in mice.Mol Med Rep. 2017 Sep;16(3):3415-3420. doi: 10.3892/mmr.2017.6958. Epub 2017 Jul 12.
|
| 155 |
Inhibition of KDM4A activity as a strategy to suppress interleukin-6 production and attenuate colitis induction.Clin Immunol. 2017 Jul;180:120-127. doi: 10.1016/j.clim.2017.05.014. Epub 2017 May 13.
|
| 156 |
VEGFR2 Signaling Prevents Colorectal Cancer Cell Senescence to Promote Tumorigenesis in Mice With Colitis.Gastroenterology. 2015 Jul;149(1):177-189.e10. doi: 10.1053/j.gastro.2015.03.016. Epub 2015 Mar 19.
|
| 157 |
KLRG1 impairs regulatory T-cell competitive fitness in the gut.Immunology. 2017 Sep;152(1):65-73. doi: 10.1111/imm.12749. Epub 2017 Jun 20.
|
| 158 |
Lactobacillus plantarum LC27 and Bifidobacterium longum LC67 simultaneously alleviate high-fat diet-induced colitis, endotoxemia, liver steatosis, and obesity in mice.Nutr Res. 2019 Jul;67:78-89. doi: 10.1016/j.nutres.2019.03.008. Epub 2019 Mar 20.
|
| 159 |
Galectin-2 suppresses contact allergy by inducing apoptosis in activated CD8+ T cells.J Immunol. 2009 May 1;182(9):5419-29. doi: 10.4049/jimmunol.0802308.
|
| 160 |
Reduced LIMK2 expression in colorectal cancer reflects its role in limiting stem cell proliferation.Gut. 2014 Mar;63(3):480-93. doi: 10.1136/gutjnl-2012-303883. Epub 2013 Apr 12.
|
| 161 |
GARP Dampens Cancer Immunity by Sustaining Function and Accumulation of Regulatory T Cells in the Colon.Cancer Res. 2019 Mar 15;79(6):1178-1190. doi: 10.1158/0008-5472.CAN-18-2623. Epub 2019 Jan 23.
|
| 162 |
l-Glutamine Attenuates DSS-Induced Colitis via Induction of MAPK Phosphatase-1.Nutrients. 2018 Mar 1;10(3):288. doi: 10.3390/nu10030288.
|
| 163 |
BLT1 in dendritic cells promotes Th1/Th17 differentiation and its deficiency ameliorates TNBS-induced colitis.Cell Mol Immunol. 2018 Dec;15(12):1047-1056. doi: 10.1038/s41423-018-0030-2. Epub 2018 Apr 18.
|
| 164 |
Two distinct leukotriene B4 receptors, BLT1 and BLT2.J Biochem. 2015 Feb;157(2):65-71. doi: 10.1093/jb/mvu078. Epub 2014 Dec 4.
|
| 165 |
Increased expression of antimicrobial peptides and lysozyme in colonic epithelial cells of patients with ulcerative colitis.Clin Exp Immunol. 2003 Jan;131(1):90-101. doi: 10.1046/j.1365-2249.2003.02035.x.
|
| 166 |
Mesenchymal MAPKAPK2/HSP27 drives intestinal carcinogenesis.Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):E5546-E5555. doi: 10.1073/pnas.1805683115. Epub 2018 May 29.
|
| 167 |
MicroRNA 429 Regulates Mucin Gene Expression and Secretion in Murine Model of Colitis.J Crohns Colitis. 2016 Jul;10(7):837-49. doi: 10.1093/ecco-jcc/jjw033. Epub 2016 Jan 27.
|
| 168 |
Immunosuppressive human anti-lymphocyte autoantibodies specific for the type 1 sphingosine 1-phosphate receptor.FASEB J. 2009 Jun;23(6):1786-96. doi: 10.1096/fj.08-124891. Epub 2009 Jan 21.
|
| 169 |
Sex steroid regulation of macrophage migration inhibitory factor in normal and inflamed colon in the female rat.Gastroenterology. 2007 Mar;132(3):982-93. doi: 10.1053/j.gastro.2006.12.028. Epub 2006 Dec 17.
|
| 170 |
Apurinic/apyrimidinic endonuclease 1, the sensitive marker for DNA deterioration in dextran sulfate sodium-induced acute colitis.Redox Rep. 2013;18(5):165-73. doi: 10.1179/1351000213Y.0000000056. Epub 2013 Jul 23.
|
| 171 |
Role of metallothioneins as danger signals in the pathogenesis of colitis.J Pathol. 2014 May;233(1):89-100. doi: 10.1002/path.4330. Epub 2014 Feb 24.
|
| 172 |
Human intestinal MUC17 mucin augments intestinal cell restitution and enhances healing of experimental colitis.Int J Biochem Cell Biol. 2010 Jun;42(6):996-1006. doi: 10.1016/j.biocel.2010.03.001. Epub 2010 Mar 6.
|
| 173 |
Epithelial RABGEF1 deficiency promotes intestinal inflammation by dysregulating intrinsic MYD88-dependent innate signaling.Mucosal Immunol. 2020 Jan;13(1):96-109. doi: 10.1038/s41385-019-0211-z. Epub 2019 Oct 18.
|
| 174 |
IFN-gamma-induced TNFR2 expression is required for TNF-dependent intestinal epithelial barrier dysfunction.Gastroenterology. 2006 Oct;131(4):1153-63. doi: 10.1053/j.gastro.2006.08.022. Epub 2006 Aug 22.
|
| 175 |
Aryl Hydrocarbon Receptor Activation Modulates Intestinal Epithelial Barrier Function by Maintaining Tight Junction Integrity.Int J Biol Sci. 2018 Jan 11;14(1):69-77. doi: 10.7150/ijbs.22259. eCollection 2018.
|
| 176 |
Reactive Oxygen Species Deficiency Due to Ncf1-Mutation Leads to Development of Adenocarcinoma and Metabolomic and Lipidomic Remodeling in a New Mouse Model of Dextran Sulfate Sodium-Induced Colitis.Front Immunol. 2018 May 14;9:701. doi: 10.3389/fimmu.2018.00701. eCollection 2018.
|
| 177 |
Pretreatment with a Heat-Killed Probiotic Modulates the NLRP3 Inflammasome and Attenuates Colitis-Associated Colorectal Cancer in Mice.Nutrients. 2019 Feb 28;11(3):516. doi: 10.3390/nu11030516.
|
| 178 |
NLRX1 Modulates Immunometabolic Mechanisms Controlling the Host-Gut Microbiota Interactions during Inflammatory Bowel Disease.Front Immunol. 2018 Feb 26;9:363. doi: 10.3389/fimmu.2018.00363. eCollection 2018.
|
| 179 |
Nod2 influences microbial resilience and susceptibility to colitis following antibiotic exposure.Mucosal Immunol. 2019 May;12(3):720-732. doi: 10.1038/s41385-018-0128-y. Epub 2019 Jan 16.
|
| 180 |
Involvement of nitric oxide with activation of Toll-like receptor 4 signaling in mice with dextran sodium sulfate-induced colitis.Free Radic Biol Med. 2014 Sep;74:108-17. doi: 10.1016/j.freeradbiomed.2014.06.020. Epub 2014 Jun 30.
|
| 181 |
eNOS plays an important role in the regulation of colonic inflammation: a novel therapeutic target and a predictive marker for the prognosis of ulcerative colitis.Free Radic Res. 2015 Jan;49(1):35-44. doi: 10.3109/10715762.2014.977788. Epub 2014 Nov 12.
|
| 182 |
Intestinal glucocorticoid synthesis enzymes in pediatric inflammatory bowel disease patients.Genes Immun. 2019 Sep;20(7):566-576. doi: 10.1038/s41435-019-0056-1. Epub 2019 Jan 28.
|
| 183 |
Blockade of Pannexin-1 Channels and Purinergic P2X7 Receptors Shows Protective Effects Against Cytokines-Induced Colitis of Human Colonic Mucosa.Front Pharmacol. 2018 Aug 6;9:865. doi: 10.3389/fphar.2018.00865. eCollection 2018.
|
| 184 |
Integrated in vivo multiomics analysis identifies p21-activated kinase signaling as a driver of colitis.Sci Signal. 2018 Feb 27;11(519):eaan3580. doi: 10.1126/scisignal.aan3580.
|
| 185 |
The incidence and relative risk of PD-1/PD-L1 inhibitors-related colitis in non-small cell lung cancer: A meta-analysis of randomized controlled trials.Int Immunopharmacol. 2019 Dec;77:105975. doi: 10.1016/j.intimp.2019.105975. Epub 2019 Nov 6.
|
| 186 |
Evidence for a causal link between adaptor protein PDZK1 downregulation and Na?H?exchanger NHE3 dysfunction in human and murine colitis.Pflugers Arch. 2015 Aug;467(8):1795-807. doi: 10.1007/s00424-014-1608-x. Epub 2014 Oct 2.
|
| 187 |
Elevated fecal peptidase D at onset of colitis in Galphai2-/- mice, a mouse model of IBD.PLoS One. 2017 Mar 21;12(3):e0174275. doi: 10.1371/journal.pone.0174275. eCollection 2017.
|
| 188 |
Inhibiting PGGT1B Disrupts Function of RHOA, Resulting in T-cell Expression of Integrin 47 and Development of Colitis in Mice.Gastroenterology. 2019 Nov;157(5):1293-1309. doi: 10.1053/j.gastro.2019.07.007. Epub 2019 Jul 11.
|
| 189 |
Phospholipase C1 links inflammation and tumorigenesis in colitis-associated cancer.Oncotarget. 2017 Dec 19;9(5):5752-5763. doi: 10.18632/oncotarget.23430. eCollection 2018 Jan 19.
|
| 190 |
Targeting phospholipase D1 attenuates intestinal tumorigenesis by controlling -catenin signaling in cancer-initiating cells.J Exp Med. 2015 Jul 27;212(8):1219-37. doi: 10.1084/jem.20141254. Epub 2015 Jun 29.
|
| 191 |
Intestinal Epithelial Cell-Specific Deletion of PLD2 Alleviates DSS-Induced Colitis by Regulating Occludin.Sci Rep. 2017 May 8;7(1):1573. doi: 10.1038/s41598-017-01797-y.
|
| 192 |
Elevated ER stress exacerbates dextran sulfate sodium-induced colitis in PRDX4-knockout mice.Free Radic Biol Med. 2019 Apr;134:153-164. doi: 10.1016/j.freeradbiomed.2018.12.024. Epub 2018 Dec 19.
|
| 193 |
Protein kinase C iota in the intestinal epithelium protects against dextran sodium sulfate-induced colitis.Inflamm Bowel Dis. 2011 Aug;17(8):1685-97. doi: 10.1002/ibd.21547. Epub 2010 Nov 15.
|
| 194 |
PRSS8 suppresses colorectal carcinogenesis and metastasis.Oncogene. 2019 Jan;38(4):497-517. doi: 10.1038/s41388-018-0453-3. Epub 2018 Aug 16.
|
| 195 |
Co-inhibition of immunoproteasome subunits LMP2 and LMP7 is required to block autoimmunity.EMBO Rep. 2018 Dec;19(12):e46512. doi: 10.15252/embr.201846512. Epub 2018 Oct 2.
|
| 196 |
The oncoprotein gankyrin promotes the development of colitis-associated cancer through activation of STAT3.Oncotarget. 2017 Apr 11;8(15):24762-24776. doi: 10.18632/oncotarget.14983.
|
| 197 |
Platelet activating factor receptor regulates colitis-induced pulmonary inflammation through the NLRP3 inflammasome.Mucosal Immunol. 2019 Jul;12(4):862-873. doi: 10.1038/s41385-019-0163-3. Epub 2019 Apr 11.
|
| 198 |
The profiling of bioactives in Akebia trifoliata pericarp and metabolites, bioavailability and in vivo anti-inflammatory activities in DSS-induced colitis mice.Food Funct. 2019 Jul 17;10(7):3977-3991. doi: 10.1039/c9fo00393b.
|
| 199 |
T-Cell-Specific PTPN2 Deficiency in NOD Mice Accelerates the Development of Type 1 Diabetes and Autoimmune Comorbidities.Diabetes. 2019 Jun;68(6):1251-1266. doi: 10.2337/db18-1362. Epub 2019 Apr 1.
|
| 200 |
Protein-tyrosine phosphatase sigma is associated with ulcerative colitis.Curr Biol. 2007 Jul 17;17(14):1212-8. doi: 10.1016/j.cub.2007.06.013. Epub 2007 Jul 5.
|
| 201 |
Epithelial cell-intrinsic Notch signaling plays an essential role in the maintenance of gut immune homeostasis.J Immunol. 2012 Mar 1;188(5):2427-36. doi: 10.4049/jimmunol.1101128. Epub 2012 Jan 25.
|
| 202 |
Deficiency in intestinal epithelial Reg4 ameliorates intestinal inflammation and alters the colonic bacterial composition.Mucosal Immunol. 2019 Jul;12(4):919-929. doi: 10.1038/s41385-019-0161-5. Epub 2019 Apr 5.
|
| 203 |
RIPK1 inhibitor ameliorates colitis by directly maintaining intestinal barrier homeostasis and regulating following IECs-immuno crosstalk.Biochem Pharmacol. 2020 Feb;172:113751. doi: 10.1016/j.bcp.2019.113751. Epub 2019 Dec 16.
|
| 204 |
Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis.Nat Immunol. 2013 Sep;14(9):927-36. doi: 10.1038/ni.2669. Epub 2013 Jul 28.
|
| 205 |
Differential responses of neurons in the rat caudal ventrolateral medulla to visceral and somatic noxious stimuli and their alterations in colitis.Brain Res Bull. 2019 Oct;152:299-310. doi: 10.1016/j.brainresbull.2019.07.030. Epub 2019 Aug 1.
|
| 206 |
Sirtuin-6 preserves R-spondin-1 expression and increases resistance of intestinal epithelium to injury in mice.Mol Med. 2017 Oct;23:272-284. doi: 10.2119/molmed.2017.00085. Epub 2017 Oct 23.
|
| 207 |
R-Spondins Are Expressed by the Intestinal Stroma and are Differentially Regulated during Citrobacter rodentium- and DSS-Induced Colitis in Mice.PLoS One. 2016 Apr 5;11(4):e0152859. doi: 10.1371/journal.pone.0152859. eCollection 2016.
|
| 208 |
Suppression Colitis and Colitis-Associated Colon Cancer by Anti-S100a9 Antibody in Mice.Front Immunol. 2017 Dec 13;8:1774. doi: 10.3389/fimmu.2017.01774. eCollection 2017.
|
| 209 |
Platelets contribute to the initiation of colitis-associated cancer by promoting immunosuppression.J Thromb Haemost. 2018 Apr;16(4):762-777. doi: 10.1111/jth.13959. Epub 2018 Mar 2.
|
| 210 |
Inflammatory hypoxia induces syndecan-2 expression through IL-1-mediated FOXO3a activation in colonic epithelia.FASEB J. 2017 Apr;31(4):1516-1530. doi: 10.1096/fj.201601098R. Epub 2016 Dec 28.
|
| 211 |
Comparison of iron-reduced and iron-supplemented semisynthetic diets in T cell transfer colitis.PLoS One. 2019 Jul 5;14(7):e0218332. doi: 10.1371/journal.pone.0218332. eCollection 2019.
|
| 212 |
Lactobacillus reuteri prevents colitis by reducing P-selectin-associated leukocyte- and platelet-endothelial cell interactions.Am J Physiol Gastrointest Liver Physiol. 2009 Mar;296(3):G534-42. doi: 10.1152/ajpgi.90470.2008. Epub 2009 Jan 15.
|
| 213 |
Immunoblockade of PSGL-1 attenuates established experimental murine colitis by reduction of leukocyte rolling.Am J Physiol Gastrointest Liver Physiol. 2004 Jul;287(1):G115-24. doi: 10.1152/ajpgi.00207.2003. Epub 2004 Mar 4.
|
| 214 |
Sphingosine-1-phosphate phosphatase 2 promotes disruption of mucosal integrity, and contributes to ulcerative colitis in mice and humans.FASEB J. 2016 Aug;30(8):2945-58. doi: 10.1096/fj.201600394R. Epub 2016 Apr 29.
|
| 215 |
SIRT5 Desuccinylates and Activates Pyruvate Kinase M2 to Block Macrophage IL-1 Production and to Prevent DSS-Induced Colitis in Mice.Cell Rep. 2017 Jun 13;19(11):2331-2344. doi: 10.1016/j.celrep.2017.05.065.
|
| 216 |
MicroRNA-193a-3p Reduces Intestinal Inflammation in Response to Microbiota via Down-regulation of Colonic PepT1.J Biol Chem. 2015 Jun 26;290(26):16099-115. doi: 10.1074/jbc.M115.659318. Epub 2015 Apr 30.
|
| 217 |
Expression and regulation of proton-coupled oligopeptide transporters in colonic tissue and immune cells of mice.Biochem Pharmacol. 2018 Feb;148:163-173. doi: 10.1016/j.bcp.2017.12.025. Epub 2018 Jan 3.
|
| 218 |
Angiotensin receptor blocker irbesartan reduces stress-induced intestinal inflammation via AT1a signaling and ACE2-dependent mechanism in mice.Brain Behav Immun. 2018 Mar;69:167-179. doi: 10.1016/j.bbi.2017.11.010. Epub 2017 Nov 16.
|
| 219 |
Immunological Characteristics of Colitis Associated with Anti-CTLA-4 Antibody Therapy.Cancer Invest. 2017 Aug 9;35(7):443-455. doi: 10.1080/07357907.2017.1324032. Epub 2017 May 26.
|
| 220 |
Nitrotyrosylation of Ca2+ channels prevents c-Src kinase regulation of colonic smooth muscle contractility in experimental colitis.J Pharmacol Exp Ther. 2007 Sep;322(3):948-56. doi: 10.1124/jpet.107.123075. Epub 2007 Jun 5.
|
| 221 |
NDR1 protein kinase promotes IL-17- and TNF--mediated inflammation by competitively binding TRAF3.EMBO Rep. 2017 Apr;18(4):586-602. doi: 10.15252/embr.201642140. Epub 2017 Feb 20.
|
| 222 |
SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer.Immunity. 2018 Sep 18;49(3):515-530.e5. doi: 10.1016/j.immuni.2018.08.024.
|
| 223 |
Truncated neurokinin-1 receptor is increased in colonic epithelial cells from patients with colitis-associated cancer.Proc Natl Acad Sci U S A. 2011 Oct 18;108(42):17420-5. doi: 10.1073/pnas.1114275108. Epub 2011 Oct 3.
|
| 224 |
TAOK1 negatively regulates IL-17-mediated signaling and inflammation.Cell Mol Immunol. 2018 Aug;15(8):794-802. doi: 10.1038/cmi.2017.158. Epub 2018 Feb 5.
|
| 225 |
TLR3 preconditioning enhances the therapeutic efficacy of umbilical cord mesenchymal stem cells in TNBS-induced colitis via the TLR3-Jagged-1-Notch-1 pathway.Mucosal Immunol. 2017 May;10(3):727-742. doi: 10.1038/mi.2016.78. Epub 2016 Sep 21.
|
| 226 |
Core fucose is essential glycosylation for CD14-dependent Toll-like receptor 4 and Toll-like receptor 2 signalling in macrophages.J Biochem. 2019 Mar 1;165(3):227-237. doi: 10.1093/jb/mvy098.
|
| 227 |
Toll-like receptor 6 stimulation promotes T-helper 1 and 17 responses in gastrointestinal-associated lymphoid tissue and modulates murine experimental colitis.Mucosal Immunol. 2014 Sep;7(5):1266-77. doi: 10.1038/mi.2014.16. Epub 2014 Mar 26.
|
| 228 |
Lactobacillus sakei S1 Improves Colitis Induced by 2,4,6-Trinitrobenzene Sulfonic Acid by the Inhibition of NF-B Signaling in Mice.J Microbiol Biotechnol. 2020 Jan 28;30(1):71-78. doi: 10.4014/jmb.1907.07050.
|
| 229 |
Affinity for self antigen selects Treg cells with distinct functional properties.Nat Immunol. 2016 Sep;17(9):1093-101. doi: 10.1038/ni.3522. Epub 2016 Aug 1.
|
| 230 |
TNF/TNFR axis promotes pyrin inflammasome activation and distinctly modulates pyrin inflammasomopathy.J Clin Invest. 2019 Jan 2;129(1):150-162. doi: 10.1172/JCI121372. Epub 2018 Nov 19.
|
| 231 |
Regulation of T cell activation in vitro and in vivo by targeting the OX40-OX40 ligand interaction: amelioration of ongoing inflammatory bowel disease with an OX40-IgG fusion protein, but not with an OX40 ligand-IgG fusion protein.J Immunol. 1999 Jan 1;162(1):486-93.
|
| 232 |
TL1A (TNFSF15) and DR3 (TNFRSF25): A Co-stimulatory System of Cytokines With Diverse Functions in Gut Mucosal Immunity.Front Immunol. 2019 Mar 27;10:583. doi: 10.3389/fimmu.2019.00583. eCollection 2019.
|
| 233 |
Involvement of Activated Cdc42 Kinase1 in Colitis and Colorectal Neoplasms.Med Sci Monit. 2016 Dec 7;22:4794-4802. doi: 10.12659/msm.902274.
|
| 234 |
Protective effects of guggulsterone against colitis are associated with the suppression of TREM-1 and modulation of macrophages.Am J Physiol Gastrointest Liver Physiol. 2018 Jul 1;315(1):G128-G139. doi: 10.1152/ajpgi.00027.2018. Epub 2018 Mar 15.
|
| 235 |
TRIM27 mediates STAT3 activation at retromer-positive structures to promote colitis and colitis-associated carcinogenesis.Nat Commun. 2018 Aug 24;9(1):3441. doi: 10.1038/s41467-018-05796-z.
|
| 236 |
TRPA1 and substance P mediate colitis in mice.Gastroenterology. 2011 Oct;141(4):1346-58. doi: 10.1053/j.gastro.2011.07.002. Epub 2011 Jul 18.
|
| 237 |
Dietary Magnesium Alleviates Experimental Murine Colitis Through Upregulation of the Transient Receptor Potential Melastatin 6 Channel.Inflamm Bowel Dis. 2018 Sep 15;24(10):2198-2210. doi: 10.1093/ibd/izy186.
|
| 238 |
TRPM8 on mucosal sensory nerves regulates colitogenic responses by innate immune cells via CGRP.Mucosal Immunol. 2015 May;8(3):491-504. doi: 10.1038/mi.2014.82. Epub 2014 Oct 1.
|
| 239 |
Rhodanese, but not cystathionine-gamma-lyase, is associated with dextran sulfate sodium-evoked colitis in mice: a sign of impaired colonic sulfide detoxification?.Toxicology. 2009 Oct 1;264(1-2):96-103. doi: 10.1016/j.tox.2009.07.018. Epub 2009 Jul 30.
|
| 240 |
Oral delivery of pancreatitis-associated protein by Lactococcus lactis displays protective effects in dinitro-benzenesulfonic-acid-induced colitis model and is able to modulate the composition of the microbiota.Environ Microbiol. 2019 Nov;21(11):4020-4031. doi: 10.1111/1462-2920.14748. Epub 2019 Sep 10.
|
| 241 |
Peroxiredoxin 1 expression in active ulcerative colitis mucosa identified by proteome analysis and involvement of thioredoxin based on immunohistochemistry.Oncol Lett. 2018 Feb;15(2):2364-2372. doi: 10.3892/ol.2017.7549. Epub 2017 Dec 8.
|
| 242 |
The ubiquitin-specific protease USP8 is critical for the development and homeostasis of T cells.Nat Immunol. 2015 Sep;16(9):950-60. doi: 10.1038/ni.3230. Epub 2015 Jul 27.
|
| 243 |
Single-Chain Variable Fragment Antibody of Vascular Cell Adhesion Molecule 1 as a Molecular Imaging Probe for Colitis Model Rabbit Investigation.Contrast Media Mol Imaging. 2019 Jan 20;2019:2783519. doi: 10.1155/2019/2783519. eCollection 2019.
|
| 244 |
Recombinant expressed vasoactive intestinal peptide analogue ameliorates TNBS-induced colitis in rats.World J Gastroenterol. 2018 Feb 14;24(6):706-715. doi: 10.3748/wjg.v24.i6.706.
|
| 245 |
Upregulation of intestinal mucosal mast cells expressing VPAC1 in close proximity to vasoactive intestinal polypeptide in inflammatory bowel disease and murine colitis.Neurogastroenterol Motil. 2019 Mar;31(3):e13503. doi: 10.1111/nmo.13503. Epub 2018 Nov 8.
|
| 246 |
B7-H4-Ig treatment of normal mice changes lymphocyte homeostasis and increases the potential of regulatory T cells.Immunopharmacol Immunotoxicol. 2013 Aug;35(4):505-13. doi: 10.3109/08923973.2013.810642. Epub 2013 Jul 10.
|
| 247 |
X-linked lymphoproliferative syndrome in mainland China: review of clinical, genetic, and immunological characteristic.Eur J Pediatr. 2020 Feb;179(2):327-338. doi: 10.1007/s00431-019-03512-7. Epub 2019 Nov 21.
|
| 248 |
The enhanced susceptibility of ADAM-17 hypomorphic mice to DSS-induced colitis is not ameliorated by loss of RIPK3, revealing an unexpected function of ADAM-17 in necroptosis.Oncotarget. 2018 Feb 5;9(16):12941-12958. doi: 10.18632/oncotarget.24410. eCollection 2018 Feb 27.
|
| 249 |
SARI attenuates colon inflammation by promoting STAT1 degradation in intestinal epithelial cells.Mucosal Immunol. 2019 Sep;12(5):1130-1140. doi: 10.1038/s41385-019-0178-9. Epub 2019 Jun 10.
|
| 250 |
Blockade of the fractalkine-CX3CR1 axis ameliorates experimental colitis by dislodging venous crawling monocytes.Int Immunol. 2019 Apr 26;31(5):287-302. doi: 10.1093/intimm/dxz006.
|
| 251 |
Faecal neutrophil elastase-antiprotease balance reflects colitis severity.Mucosal Immunol. 2020 Mar;13(2):322-333. doi: 10.1038/s41385-019-0235-4. Epub 2019 Nov 26.
|
| 252 |
Protease-activated receptor 2 signaling modulates susceptibility of colonic epithelium to injury through stabilization of YAP in vivo.Cell Death Dis. 2018 Sep 20;9(10):949. doi: 10.1038/s41419-018-0995-x.
|
| 253 |
Kynurenic acid/GPR35 axis restricts NLRP3 inflammasome activation and exacerbates colitis in mice with social stress.Brain Behav Immun. 2019 Jul;79:244-255. doi: 10.1016/j.bbi.2019.02.009. Epub 2019 Feb 18.
|
| 254 |
Myeloid p38 signaling promotes intestinal IGF-1 production and inflammation-associated tumorigenesis.EMBO Mol Med. 2018 Jul;10(7):e8403. doi: 10.15252/emmm.201708403.
|
| 255 |
Role of MAdCAM-1-Expressing High Endothelial Venule-Like Vessels in Colitis Induced in Mice Lacking Sulfotransferases Catalyzing L-Selectin Ligand Biosynthesis.J Histochem Cytochem. 2018 Jun;66(6):415-425. doi: 10.1369/0022155417753363. Epub 2018 Jan 19.
|
| 256 |
NAD metabolism fuels human and mouse intestinal inflammation.Gut. 2018 Oct;67(10):1813-1823. doi: 10.1136/gutjnl-2017-314241. Epub 2017 Sep 6.
|
| 257 |
Ciclosporin Therapy After Infliximab Failure in Hospitalized Patients With Acute Severe Colitis is Effective and Safe.J Crohns Colitis. 2019 Sep 19;13(9):1105-1110. doi: 10.1093/ecco-jcc/jjz032.
|
| 258 |
Impact of Food Additives on Gut Homeostasis.Nutrients. 2019 Oct 1;11(10):2334. doi: 10.3390/nu11102334.
|
| 259 |
Plasmacytoid Dendritic Cells Are Largely Dispensable for the Pathogenesis of Experimental Inflammatory Bowel Disease.Front Immunol. 2018 Oct 25;9:2475. doi: 10.3389/fimmu.2018.02475. eCollection 2018.
|
| 260 |
Adaptation to inflammatory acidity through neutrophil-derived adenosine regulation of SLC26A3.Mucosal Immunol. 2020 Mar;13(2):230-244. doi: 10.1038/s41385-019-0237-2. Epub 2019 Dec 2.
|
| 261 |
Mechanism of down regulation of Na-H exchanger-2 in experimental colitis.PLoS One. 2017 May 11;12(5):e0176767. doi: 10.1371/journal.pone.0176767. eCollection 2017.
|
| 262 |
PHD3 Stabilizes the Tight Junction Protein Occludin and Protects Intestinal Epithelial Barrier Function.J Biol Chem. 2015 Aug 14;290(33):20580-9. doi: 10.1074/jbc.M115.653584. Epub 2015 Jun 29.
|
| 263 |
The endogenous bioactive lipid prostaglandin D(2)-glycerol ester reduces murine colitis via DP1 and PPAR receptors.FASEB J. 2018 Sep;32(9):5000-5011. doi: 10.1096/fj.201701205R. Epub 2018 Apr 9.
|
| 264 |
Mucosal function in rat jejunum and ileum is altered by induction of colitis.Int J Mol Med. 2006 Oct;18(4):721-7.
|
| 265 |
Mice overexpressing -1,4-Galactosyltransferase I are resistant to TNF-induced inflammation and DSS-induced colitis.PLoS One. 2013 Dec 5;8(12):e79883. doi: 10.1371/journal.pone.0079883. eCollection 2013.
|
| 266 |
Increased CYP4B1 mRNA is associated with the inhibition of dextran sulfate sodium-induced colitis by caffeic acid in mice.Exp Biol Med (Maywood). 2009 Jun;234(6):605-16. doi: 10.3181/0901-RM-1. Epub 2009 Mar 23.
|
| 267 |
Resolution of inflammatory colitis with pegfilgrastim treatment in a case of severe congenital neutropenia due to glucose 6 phosphatase catalytic subunit-3 deficiency.J Pediatr Hematol Oncol. 2014 Jul;36(5):e316-8. doi: 10.1097/MPH.0000000000000079.
|
| 268 |
Phenotype-stratified genetic linkage study demonstrates that IBD2 is an extensive ulcerative colitis locus.Am J Gastroenterol. 2006 Mar;101(3):572-80. doi: 10.1111/j.1572-0241.2006.00451.x.
|
| 269 |
Antitumor Activity and Treatment-Related Toxicity Associated With Nivolumab Plus Ipilimumab in Advanced Malignancies: A Systematic Review and Meta-Analysis.Front Pharmacol. 2019 Nov 4;10:1300. doi: 10.3389/fphar.2019.01300. eCollection 2019.
|
| 270 |
Glutathione S-transferase alpha 4 induction by activator protein 1 in colorectal cancer.Oncogene. 2016 Nov 3;35(44):5795-5806. doi: 10.1038/onc.2016.113. Epub 2016 Apr 11.
|
| 271 |
Distinct immunomodulatory effects of spermine oxidase in colitis induced by epithelial injury or infection. Front Immunol. 2018 Jun 5;9:1242.
|
| 272 |
Interferon--mediated secretion of tryptophanyl-tRNA synthetases has a role in protection of human umbilical cord blood-derived mesenchymal stem cells against experimental colitis.BMB Rep. 2019 May;52(5):318-323. doi: 10.5483/BMBRep.2019.52.5.134.
|
| 273 |
Neutralization of IL-1 ameliorates Crohn's disease-like ileitis by functional alterations of the gut microbiome.Proc Natl Acad Sci U S A. 2019 Dec 26;116(52):26717-26726. doi: 10.1073/pnas.1915043116. Epub 2019 Dec 16.
|
| 274 |
The protection role of Atg16l1 in CD11c(+)dendritic cells in murine colitis.Immunobiology. 2017 Jul;222(7):831-841. doi: 10.1016/j.imbio.2017.03.002. Epub 2017 Mar 16.
|
| 275 |
Elevated levels of Bcl-3 inhibits Treg development and function resulting in spontaneous colitis.Nat Commun. 2017 Apr 28;8:15069. doi: 10.1038/ncomms15069.
|
| 276 |
MicroRNA-146a-5p attenuates visceral hypersensitivity through targeting chemokine CCL8 in the spinal cord in a mouse model of colitis.Brain Res Bull. 2018 May;139:235-242. doi: 10.1016/j.brainresbull.2018.03.007. Epub 2018 Mar 14.
|
| 277 |
Ceramide Synthase 6 Deficiency Enhances Inflammation in the DSS model of Colitis.Sci Rep. 2018 Jan 26;8(1):1627. doi: 10.1038/s41598-018-20102-z.
|
| 278 |
Upregulated claudin-1 expression promotes colitis-associated cancer by promoting -catenin phosphorylation and activation in Notch/p-AKT-dependent manner.Oncogene. 2019 Jun;38(26):5321-5337. doi: 10.1038/s41388-019-0795-5. Epub 2019 Apr 10.
|
| 279 |
Homoectoine Protects Against Colitis by Preventing a Claudin Switch in Epithelial Tight Junctions.Dig Dis Sci. 2019 Feb;64(2):409-420. doi: 10.1007/s10620-018-5309-8. Epub 2018 Sep 29.
|
| 280 |
The role of Cortistatin-14 in the gastrointestinal motility in mice.Pharmacol Rep. 2018 Apr;70(2):355-363. doi: 10.1016/j.pharep.2017.09.004. Epub 2017 Sep 18.
|
| 281 |
Endothelial MT1-MMP targeting limits intussusceptive angiogenesis and colitis via TSP1/nitric oxide axis.EMBO Mol Med. 2020 Feb 7;12(2):e10862. doi: 10.15252/emmm.201910862. Epub 2019 Dec 3.
|
| 282 |
Copy number variation of scavenger-receptor cysteine-rich domains within DMBT1 and Crohn's disease.Eur J Hum Genet. 2016 Aug;24(9):1294-300. doi: 10.1038/ejhg.2015.280. Epub 2016 Jan 27.
|
| 283 |
5-Hydroxytryptamine (5-HT)-exacerbated DSS-induced colitis is associated with elevated NADPH oxidase expression in the colon.J Cell Biochem. 2019 Jun;120(6):9230-9242. doi: 10.1002/jcb.28198. Epub 2018 Dec 7.
|
| 284 |
FNDC4 Inhibits RANKL-Induced Osteoclast Formation by Suppressing NF-B Activation and CXCL10 Expression.Biomed Res Int. 2018 May 30;2018:3936257. doi: 10.1155/2018/3936257. eCollection 2018.
|
| 285 |
Gimap5-dependent inactivation of GSK3 is required for CD4(+) T cell homeostasis and prevention of immune pathology.Nat Commun. 2018 Jan 30;9(1):430. doi: 10.1038/s41467-018-02897-7.
|
| 286 |
Lack of the pH-sensing Receptor TDAG8 [GPR65] in Macrophages Plays a Detrimental Role in Murine Models of Inflammatory Bowel Disease.J Crohns Colitis. 2019 Feb 1;13(2):245-258. doi: 10.1093/ecco-jcc/jjy152.
|
| 287 |
Distinct and overlapping functions of glutathione peroxidases 1 and 2 in limiting NF-B-driven inflammation through redox-active mechanisms.Redox Biol. 2020 Jan;28:101388. doi: 10.1016/j.redox.2019.101388. Epub 2019 Nov 16.
|
| 288 |
Identification of New Potential Therapies for Colitis Amelioration Using an Appendicitis-Appendectomy Model.Inflamm Bowel Dis. 2019 Feb 21;25(3):436-444. doi: 10.1093/ibd/izy332.
|
| 289 |
Modified apple polysaccharide prevents colitis through modulating IL-22 and IL-22BP expression.Int J Biol Macromol. 2017 Oct;103:1217-1223. doi: 10.1016/j.ijbiomac.2017.05.172. Epub 2017 Jun 1.
|
| 290 |
IRF4 regulates IL-17A promoter activity and controls RORt-dependent Th17 colitis in vivo.Inflamm Bowel Dis. 2011 Jun;17(6):1343-58. doi: 10.1002/ibd.21476. Epub 2011 Feb 8.
|
| 291 |
PAP-1 ameliorates DSS-induced colitis with involvement of NLRP3 inflammasome pathway.Int Immunopharmacol. 2019 Oct;75:105776. doi: 10.1016/j.intimp.2019.105776. Epub 2019 Jul 24.
|
| 292 |
Lypd8 inhibits attachment of pathogenic bacteria to colonic epithelia.Mucosal Immunol. 2020 Jan;13(1):75-85. doi: 10.1038/s41385-019-0219-4. Epub 2019 Oct 28.
|
| 293 |
Gut Inflammation in Mice Triggers Proliferation and Function of Mucosal Foxp3+ Regulatory T Cells but Impairs Their Conversion from CD4+ T Cells.J Crohns Colitis. 2017 Jan;11(1):105-117. doi: 10.1093/ecco-jcc/jjw125. Epub 2016 Jun 30.
|
| 294 |
The immunomodulatory effects of adipose-derived mesenchymal stem cells and mesenchymal stem cells-conditioned medium in chronic colitis.J Cell Physiol. 2018 Nov;233(11):8754-8766. doi: 10.1002/jcp.26765. Epub 2018 May 24.
|
| 295 |
Adjunctive fecal microbiota transplantation in supportive oncology: Emerging indications and considerations in immunocompromised patients.EBioMedicine. 2019 Jun;44:730-740. doi: 10.1016/j.ebiom.2019.03.070. Epub 2019 Mar 30.
|
| 296 |
MUC13 promotes the development of colitis-associated colorectal tumors via -catenin activity.Oncogene. 2019 Nov;38(48):7294-7310. doi: 10.1038/s41388-019-0951-y. Epub 2019 Aug 19.
|
| 297 |
Generation of novel monoclonal antibodies and their application for detecting ARD1 expression in colorectal cancer.Cancer Lett. 2008 Jun 8;264(1):83-92. doi: 10.1016/j.canlet.2008.01.028. Epub 2008 Mar 5.
|
| 298 |
Roseburia intestinalis inhibits oncostatin M and maintains tight junction integrity in a murine model of acute experimental colitis.Scand J Gastroenterol. 2019 Apr;54(4):432-440. doi: 10.1080/00365521.2019.1595708. Epub 2019 Apr 4.
|
| 299 |
Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier function.Gastroenterology. 2010 Dec;139(6):2093-101. doi: 10.1053/j.gastro.2010.06.068. Epub 2010 Jun 30.
|
| 300 |
Hobit- and Blimp-1-driven CD4(+) tissue-resident memory T cells control chronic intestinal inflammation.Nat Immunol. 2019 Mar;20(3):288-300. doi: 10.1038/s41590-018-0298-5. Epub 2019 Jan 28.
|
| 301 |
T cell-derived protein S engages TAM receptor signaling in dendritic cells to control the magnitude of the immune response.Immunity. 2013 Jul 25;39(1):160-70. doi: 10.1016/j.immuni.2013.06.010. Epub 2013 Jul 11.
|
| 302 |
Experimental colitis in IL-10-deficient mice ameliorates in the absence of PTPN22.Clin Exp Immunol. 2019 Sep;197(3):263-275. doi: 10.1111/cei.13339. Epub 2019 Jul 10.
|
| 303 |
Pyroglutamide-Based P2X7 Receptor Antagonists Targeting Inflammatory Bowel Disease.J Med Chem. 2020 Mar 12;63(5):2074-2094. doi: 10.1021/acs.jmedchem.9b00584. Epub 2019 Sep 27.
|
| 304 |
Reelin expression is up-regulated in mice colon in response to acute colitis and provides resistance against colitis.Biochim Biophys Acta Mol Basis Dis. 2017 Feb;1863(2):462-473. doi: 10.1016/j.bbadis.2016.11.028. Epub 2016 Nov 30.
|
| 305 |
Environmental Factors Modify the Severity of Acute DSS Colitis in Caspase-11-Deficient Mice.Inflamm Bowel Dis. 2018 Oct 12;24(11):2394-2403. doi: 10.1093/ibd/izy244.
|
| 306 |
Low Dose of Cyanidin-3-O-Glucoside Alleviated Dextran Sulfate Sodium-Induced Colitis, Mediated by CD169+ Macrophage Pathway.Inflamm Bowel Dis. 2019 Aug 20;25(9):1510-1521. doi: 10.1093/ibd/izz090.
|
| 307 |
Alterations in the p53-SOCS2 axis contribute to tumor growth in colon cancer.Exp Mol Med. 2018 Apr 6;50(4):1-10. doi: 10.1038/s12276-017-0001-1.
|
| 308 |
Dual roles of IL-18 in colitis through regulation of the function and quantity of goblet cells.Int J Mol Med. 2019 Jun;43(6):2291-2302. doi: 10.3892/ijmm.2019.4156. Epub 2019 Apr 4.
|
| 309 |
COMP-angiopoietin-1 ameliorates inflammation-induced lymphangiogenesis in dextran sulfate sodium (DSS)-induced colitis model.J Mol Med (Berl). 2018 May;96(5):459-467. doi: 10.1007/s00109-018-1633-x. Epub 2018 Apr 2.
|
| 310 |
A novel model of colitis-associated cancer in SAMP1/YitFc mice with Crohn's disease-like ileitis.PLoS One. 2017 Mar 16;12(3):e0174121. doi: 10.1371/journal.pone.0174121. eCollection 2017.
|
| 311 |
TSG-6 released from intraperitoneally injected canine adipose tissue-derived mesenchymal stem cells ameliorate inflammatory bowel disease by inducing M2 macrophage switch in mice.Stem Cell Res Ther. 2018 Apr 6;9(1):91. doi: 10.1186/s13287-018-0841-1.
|
| 312 |
Glucocorticoid-Induced Leucine Zipper: A Novel Anti-inflammatory Molecule.Front Pharmacol. 2019 Mar 27;10:308. doi: 10.3389/fphar.2019.00308. eCollection 2019.
|
| 313 |
Malassezia Is Associated with Crohn's Disease and Exacerbates Colitis in Mouse Models.Cell Host Microbe. 2019 Mar 13;25(3):377-388.e6. doi: 10.1016/j.chom.2019.01.007. Epub 2019 Mar 5.
|
| 314 |
Keratin 8 reduces colonic permeability and maintains gut microbiota homeostasis, protecting against colitis and colitis-associated tumorigenesis.Oncotarget. 2017 May 27;8(57):96774-96790. doi: 10.18632/oncotarget.18241. eCollection 2017 Nov 14.
|
| 315 |
Transcription factor NFATc2 controls the emergence of colon cancer associated with IL-6-dependent colitis.Cancer Res. 2012 Sep 1;72(17):4340-50. doi: 10.1158/0008-5472.CAN-11-4155. Epub 2012 Jun 27.
|
| 316 |
Arsenic trioxide ameliorates murine colon inflammation through inflammatory cell enzymatic modulation.Naunyn Schmiedebergs Arch Pharmacol. 2019 Feb;392(2):259-270. doi: 10.1007/s00210-018-1578-1. Epub 2018 Nov 10.
|
| 317 |
Huang Qi Jian Zhong Pellet Attenuates TNBS-Induced Colitis in Rats via Mechanisms Involving Improvement of Energy Metabolism.Evid Based Complement Alternat Med. 2013;2013:574629. doi: 10.1155/2013/574629. Epub 2013 Jun 6.
|
| 318 |
Loss of BID Delays FASL-Induced Cell Death of Mouse Neutrophils and Aggravates DSS-Induced Weight Loss.Int J Mol Sci. 2018 Feb 28;19(3):684. doi: 10.3390/ijms19030684.
|
| 319 |
FAM96A Protects Mice From Dextran Sulfate Sodium (DSS)-Induced Colitis by Preventing Microbial Dysbiosis.Front Cell Infect Microbiol. 2019 Nov 18;9:381. doi: 10.3389/fcimb.2019.00381. eCollection 2019.
|
| 320 |
Desmocollin switching in colorectal cancer.Br J Cancer. 2006 Nov 20;95(10):1367-70. doi: 10.1038/sj.bjc.6603453. Epub 2006 Oct 31.
|
| 321 |
FSGHF3 and peptides, prepared from fish skin gelatin, exert a protective effect on DSS-induced colitis via the Nrf2 pathway.Food Funct. 2020 Jan 29;11(1):414-423. doi: 10.1039/c9fo02165e.
|
| 322 |
Early detection of renal injury using urinary vanin-1 in rats with experimental colitis.J Appl Toxicol. 2014 Feb;34(2):184-90. doi: 10.1002/jat.2849. Epub 2013 Jan 11.
|
| 323 |
The signaling axis of microRNA-31/interleukin-25 regulates Th1/Th17-mediated inflammation response in colitis.Mucosal Immunol. 2017 Jul;10(4):983-995. doi: 10.1038/mi.2016.102. Epub 2016 Nov 30.
|
| 324 |
Dietary supplementation of krill oil attenuates inflammation and oxidative stress in experimental ulcerative colitis in rats.Scand J Gastroenterol. 2012 Jan;47(1):49-58. doi: 10.3109/00365521.2011.634025. Epub 2011 Nov 30.
|
| 325 |
Combined NADPH oxidase 1 and interleukin 10 deficiency induces chronic endoplasmic reticulum stress and causes ulcerative colitis-like disease in mice.PLoS One. 2014 Jul 9;9(7):e101669. doi: 10.1371/journal.pone.0101669. eCollection 2014.
|
| 326 |
Diet Rich in Animal Protein Promotes Pro-inflammatory Macrophage Response and Exacerbates Colitis in Mice.Front Immunol. 2019 Apr 26;10:919. doi: 10.3389/fimmu.2019.00919. eCollection 2019.
|
| 327 |
Protein tyrosine phosphatase targets apical junction complex proteins in the intestine and regulates epithelial permeability.Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):693-8. doi: 10.1073/pnas.1315017111. Epub 2014 Jan 2.
|
| 328 |
Ulcerative colitis, Crohn's disease, and irritable bowel syndrome have different profiles of extracellular matrix turnover, which also reflects disease activity in Crohn's disease.PLoS One. 2017 Oct 13;12(10):e0185855. doi: 10.1371/journal.pone.0185855. eCollection 2017.
|
| 329 |
Adamts18 deficiency promotes colon carcinogenesis by enhancing -catenin and p38MAPK/ERK1/2 signaling in the mouse model of AOM/DSS-induced colitis-associated colorectal cancer.Oncotarget. 2017 Mar 21;8(12):18979-18990. doi: 10.18632/oncotarget.14866.
|
| 330 |
Boosting Apoptotic Cell Clearance by Colonic Epithelial Cells Attenuates Inflammation In Vivo.Immunity. 2016 Apr 19;44(4):807-20. doi: 10.1016/j.immuni.2016.02.005. Epub 2016 Mar 29.
|
| 331 |
Contribution of adenosine A2B receptors to inflammatory parameters of experimental colitis.J Immunol. 2009 Apr 15;182(8):4957-64. doi: 10.4049/jimmunol.0801324.
|
| 332 |
Ameliorating effect of TI-1-162, a hydroxyindenone derivative, against TNBS-induced rat colitis is mediated through suppression of RIP/ASK-1/MAPK signaling.Eur J Pharmacol. 2018 May 15;827:94-102. doi: 10.1016/j.ejphar.2018.03.027. Epub 2018 Mar 16.
|
| 333 |
Suppression of epithelial restitution using an inhibitor against Rho-associated coiled-coil containing protein kinase aggravates colitis through reduced epithelial expression of A-kinase anchor protein 13.Exp Toxicol Pathol. 2017 Oct 2;69(8):557-563. doi: 10.1016/j.etp.2017.05.001. Epub 2017 May 20.
|
| 334 |
Structural characterization of water-soluble polysaccharide from Arctium lappa and its effects on colitis mice.Carbohydr Polym. 2019 Jun 1;213:89-99. doi: 10.1016/j.carbpol.2019.02.090. Epub 2019 Feb 27.
|
| 335 |
Alpha kinase 1 controls intestinal inflammation by suppressing the IL-12/Th1 axis.Nat Commun. 2018 Sep 18;9(1):3797. doi: 10.1038/s41467-018-06085-5.
|
| 336 |
Loss of acid ceramidase in myeloid cells suppresses intestinal neutrophil recruitment.FASEB J. 2018 May;32(5):2339-2353. doi: 10.1096/fj.201700585R. Epub 2017 Dec 19.
|
| 337 |
Ascl2 facilitates IL-10 production in Th17 cells to restrain their pathogenicity in inflammatory bowel disease.Biochem Biophys Res Commun. 2019 Mar 12;510(3):435-441. doi: 10.1016/j.bbrc.2019.01.123. Epub 2019 Feb 2.
|
| 338 |
Ash1l and lnc-Smad3 coordinate Smad3 locus accessibility to modulate iTreg polarization and T cell autoimmunity.Nat Commun. 2017 Jun 9;8:15818. doi: 10.1038/ncomms15818.
|
| 339 |
Schiff base complexes of copper and zinc as potential anti-colitic compounds.Biometals. 2017 Jun;30(3):423-439. doi: 10.1007/s10534-017-0016-z. Epub 2017 Apr 19.
|
| 340 |
MiR-29a inhibited intestinal epithelial cells autophagy partly by decreasing ATG9A in ulcerative colitis.Anticancer Drugs. 2018 Aug;29(7):652-659. doi: 10.1097/CAD.0000000000000636.
|
| 341 |
Colitis Is Effectively Ameliorated by ()-8-Acetonyl-dihydrocoptisine via the XBP1-NF-B Pathway.Front Pharmacol. 2017 Sep 5;8:619. doi: 10.3389/fphar.2017.00619. eCollection 2017.
|
| 342 |
Regulation of T cell lineage commitment by SMAR1 during inflammatory & autoimmune diseases.Indian J Med Res. 2015 Oct;142(4):405-13. doi: 10.4103/0971-5916.169198.
|
| 343 |
Novel Colitis Immunotherapy Targets Bin1 and Improves Colon Cell Barrier Function.Dig Dis Sci. 2016 Feb;61(2):423-32. doi: 10.1007/s10620-015-3804-8. Epub 2015 Jul 21.
|
| 344 |
BTNL2, a butyrophilin/B7-like molecule, is a negative costimulatory molecule modulated in intestinal inflammation.J Immunol. 2007 Feb 1;178(3):1523-33. doi: 10.4049/jimmunol.178.3.1523.
|
| 345 |
Nuclear translocation of H2RSP is impaired in regenerating intestinal epithelial cells of murine colitis model.Virchows Arch. 2006 Mar;448(3):354-60. doi: 10.1007/s00428-005-0064-6. Epub 2005 Sep 28.
|
| 346 |
The BAG-1 isoform BAG-1M regulates keratin-associated Hsp70 chaperoning of aPKC in intestinal cells during activation of inflammatory signaling.J Cell Sci. 2014 Aug 15;127(Pt 16):3568-77. doi: 10.1242/jcs.151084. Epub 2014 May 29.
|
| 347 |
Calcium/calmodulin-dependent protein kinase IV (CaMKIV) activation contributes to the pathogenesis of experimental colitis via inhibition of intestinal epithelial cell proliferation.FASEB J. 2019 Jan;33(1):1330-1346. doi: 10.1096/fj.201800535R. Epub 2018 Aug 16.
|
| 348 |
In situ self-spray coating system that can uniformly disperse a poorly water-soluble H(2)S donor on the colorectal surface to treat inflammatory bowel diseases.Biomaterials. 2018 Nov;182:289-298. doi: 10.1016/j.biomaterials.2018.07.044. Epub 2018 Aug 16.
|
| 349 |
Calpastatin prevents NF-B-mediated hyperactivation of macrophages and attenuates colitis.J Immunol. 2013 Oct 1;191(7):3778-88. doi: 10.4049/jimmunol.1300972. Epub 2013 Aug 28.
|
| 350 |
MTGR1 is required for tumorigenesis in the murine AOM/DSS colitis-associated carcinoma model.Cancer Res. 2011 Feb 15;71(4):1302-12. doi: 10.1158/0008-5472.CAN-10-3317. Epub 2011 Feb 8.
|
| 351 |
Kaiso is required for MTG16-dependent effects on colitis-associated carcinoma.Oncogene. 2019 Jun;38(25):5091-5106. doi: 10.1038/s41388-019-0777-7. Epub 2019 Mar 11.
|
| 352 |
Dro1/Ccdc80 inactivation promotes AOM/DSS-induced colorectal carcinogenesis and aggravates colitis by DSS in mice.Carcinogenesis. 2018 Sep 21;39(9):1176-1184. doi: 10.1093/carcin/bgy077.
|
| 353 |
CCDC88B is required for pathogenesis of inflammatory bowel disease.Nat Commun. 2017 Oct 13;8(1):932. doi: 10.1038/s41467-017-01381-y.
|
| 354 |
CCL28-Deficient Mice Have Reduced IgA Antibody-Secreting Cells and an Altered Microbiota in the Colon.J Immunol. 2018 Jan 15;200(2):800-809. doi: 10.4049/jimmunol.1700037. Epub 2017 Dec 13.
|
| 355 |
Dipotassium Glycyrrhizate Improves Intestinal Mucosal Healing by Modulating Extracellular Matrix Remodeling Genes and Restoring Epithelial Barrier Functions.Front Immunol. 2019 Apr 26;10:939. doi: 10.3389/fimmu.2019.00939. eCollection 2019.
|
| 356 |
Functional characterization of CXCR4 in mediating the expression of protein C system in experimental ulcerative colitis.Am J Transl Res. 2017 Nov 15;9(11):4821-4835. eCollection 2017.
|
| 357 |
CD101 inhibits the expansion of colitogenic T cells.Mucosal Immunol. 2016 Sep;9(5):1205-17. doi: 10.1038/mi.2015.139. Epub 2016 Jan 27.
|
| 358 |
CD177+ neutrophils suppress epithelial cell tumourigenesis in colitis-associated cancer and predict good prognosis in colorectal cancer.Carcinogenesis. 2018 Feb 9;39(2):272-282. doi: 10.1093/carcin/bgx142.
|
| 359 |
Deletion of cadherin-17 enhances intestinal permeability andsusceptibility to intestinal tumour formation.J Pathol. 2018 Nov;246(3):289-299. doi: 10.1002/path.5138. Epub 2018 Sep 25.
|
| 360 |
Loss of C/EBP enhances apoptosis of intestinal epithelial cells and exacerbates experimental colitis in mice.Genes Cells. 2019 Sep;24(9):619-626. doi: 10.1111/gtc.12711. Epub 2019 Jul 15.
|
| 361 |
Ablation of ceramide synthase 2 exacerbates dextran sodium sulphate-induced colitis in mice due to increased intestinal permeability.J Cell Mol Med. 2017 Dec;21(12):3565-3578. doi: 10.1111/jcmm.13267. Epub 2017 Jul 12.
|
| 362 |
MicroRNA 429 regulates the expression of CHMP5 in the inflammatory colitis and colorectal cancer cells.Inflamm Res. 2018 Dec;67(11-12):985-996. doi: 10.1007/s00011-018-1194-z. Epub 2018 Oct 17.
|
| 363 |
Impact of Sensitization and Inflammation on the Interaction of Mast Cells With the Intestinal Epithelium in Rats.Front Physiol. 2019 Mar 26;10:329. doi: 10.3389/fphys.2019.00329. eCollection 2019.
|
| 364 |
Cortical Inflammation is Increased in a DSS-Induced Colitis Mouse Model.Neurosci Bull. 2018 Dec;34(6):1058-1066. doi: 10.1007/s12264-018-0288-5. Epub 2018 Sep 17.
|
| 365 |
Pro-inflammatory miR-223 mediates the cross-talk between the IL23 pathway and the intestinal barrier in inflammatory bowel disease.Genome Biol. 2016 Mar 30;17:58. doi: 10.1186/s13059-016-0901-8.
|
| 366 |
Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis.Science. 2012 Jun 8;336(6086):1314-7. doi: 10.1126/science.1221789. Epub 2012 Jun 6.
|
| 367 |
Anti-Inflammatory and Anti-Oxidant Effects of p-Chloro-phenyl-selenoesterol on TNBS-Induced Inflammatory Bowel Disease in Mice.J Cell Biochem. 2017 Apr;118(4):709-717. doi: 10.1002/jcb.25670. Epub 2016 Dec 29.
|
| 368 |
Copper metabolism domain-containing 1 represses genes that promote inflammation and protects mice from colitis and colitis-associated cancer.Gastroenterology. 2014 Jul;147(1):184-195.e3. doi: 10.1053/j.gastro.2014.04.007. Epub 2014 Apr 13.
|
| 369 |
Impaired COMMD10-Mediated Regulation of Ly6C(hi) Monocyte-Driven Inflammation Disrupts Gut Barrier Function.Front Immunol. 2018 Nov 14;9:2623. doi: 10.3389/fimmu.2018.02623. eCollection 2018.
|
| 370 |
Protective effect of biogenic polyphosphate nanoparticles from Synechococcus sp. PCC 7002 on dextran sodium sulphate-induced colitis in mice.Food Funct. 2019 Feb 20;10(2):1007-1016. doi: 10.1039/c8fo01861h.
|
| 371 |
Cancer testis antigen 55 deficiency attenuates colitis-associated colorectal cancer by inhibiting NF-B signaling.Cell Death Dis. 2019 Apr 3;10(4):304. doi: 10.1038/s41419-019-1537-x.
|
| 372 |
The octapetide NAP alleviates intestinal and extra-intestinal anti-inflammatory sequelae of acute experimental colitis.Peptides. 2018 Mar;101:1-9. doi: 10.1016/j.peptides.2017.12.023. Epub 2017 Dec 27.
|
| 373 |
Dysregulation of the miR-324-5p-CUEDC2 axis leads to macrophage dysfunction and is associated with colon cancer.Cell Rep. 2014 Jun 26;7(6):1982-93. doi: 10.1016/j.celrep.2014.05.007. Epub 2014 May 29.
|
| 374 |
Actin related protein 3 (ARP3) promotes apoptosis of intestinal epithelial cells in ulcerative colitis.Pathol Res Pract. 2019 Feb;215(2):235-242. doi: 10.1016/j.prp.2018.10.011. Epub 2018 Oct 24.
|
| 375 |
A homozygous loss-of-function mutation leading to CYBC1 deficiency causes chronic granulomatous disease. Nat Commun. 2018 Oct 25;9(1):4447. doi: 10.1038/s41467-018-06964-x.
|
| 376 |
Cytoglobin affects tumorigenesis and the expression of ulcerative colitis-associated genes under chemically induced colitis in mice.Sci Rep. 2018 May 2;8(1):6905. doi: 10.1038/s41598-018-24728-x.
|
| 377 |
Rapid Downregulation of DAB2 by Toll-Like Receptor Activation Contributes to a Pro-Inflammatory Switch in Activated Dendritic Cells.Front Immunol. 2019 Feb 27;10:304. doi: 10.3389/fimmu.2019.00304. eCollection 2019.
|
| 378 |
Murine DX5(+)NKT Cells Display Their Cytotoxic and Proapoptotic Potentials against Colitis-Inducing CD4(+)CD62L(high) T Cells through Fas Ligand.J Immunol Res. 2018 Sep 30;2018:8175810. doi: 10.1155/2018/8175810. eCollection 2018.
|
| 379 |
Nucleic acid sensing pattern recognition receptors in the development of colorectal cancer and colitis.Cell Mol Life Sci. 2017 Jul;74(13):2395-2411. doi: 10.1007/s00018-017-2477-1. Epub 2017 Feb 21.
|
| 380 |
Inhibition of colon carcinogenesis by 2-methoxy-5-amino-N-hydroxybenzamide, a novel derivative of mesalamine.Gastroenterology. 2010 Jan;138(1):221-30. doi: 10.1053/j.gastro.2009.08.062. Epub 2009 Sep 6.
|
| 381 |
Neurotrophic factor GDNF regulates intestinal barrier function in inflammatory bowel disease.J Clin Invest. 2019 Jun 17;129(7):2824-2840. doi: 10.1172/JCI120261. eCollection 2019 Jun 17.
|
| 382 |
Separation of Dual Oxidase 2 and Lactoperoxidase Expression in Intestinal Crypts and Species Differences May Limit Hydrogen Peroxide Scavenging During Mucosal Healing in Mice and Humans.Inflamm Bowel Dis. 2017 Dec 19;24(1):136-148. doi: 10.1093/ibd/izx024.
|
| 383 |
The phosphatase DUSP2 controls the activity of the transcription activator STAT3 and regulates TH17 differentiation.Nat Immunol. 2015 Dec;16(12):1263-73. doi: 10.1038/ni.3278. Epub 2015 Oct 19.
|
| 384 |
Dual-specificity phosphatase 6 deletion protects the colonic epithelium against inflammation and promotes both proliferation and tumorigenesis.J Cell Physiol. 2019 May;234(5):6731-6745. doi: 10.1002/jcp.27420. Epub 2018 Oct 1.
|
| 385 |
Andrographolide Derivative AL-1 Ameliorates Dextran Sodium Sulfate-Induced Murine Colitis by Inhibiting NF-B and MAPK Signaling Pathways.Oxid Med Cell Longev. 2019 Oct 7;2019:6138723. doi: 10.1155/2019/6138723. eCollection 2019.
|
| 386 |
Spliceosome protein Eftud2 promotes colitis-associated tumorigenesis by modulating inflammatory response of macrophage.Mucosal Immunol. 2019 Sep;12(5):1164-1173. doi: 10.1038/s41385-019-0184-y. Epub 2019 Jul 5.
|
| 387 |
Epithelial-specific ETS-1 (ESE1/ELF3) regulates apoptosis of intestinal epithelial cells in ulcerative colitis via accelerating NF-B activation.Immunol Res. 2015 Jun;62(2):198-212. doi: 10.1007/s12026-015-8651-3.
|
| 388 |
Engulfment and Cell Motility Protein 1 Protects Against DSS-induced Colonic Injury in Mice via Rac1 Activation.J Crohns Colitis. 2019 Jan 1;13(1):100-114. doi: 10.1093/ecco-jcc/jjy133.
|
| 389 |
Abrogation of EMILIN1-1 integrin interaction promotes experimental colitis and colon carcinogenesis.Matrix Biol. 2019 Oct;83:97-115. doi: 10.1016/j.matbio.2019.08.006. Epub 2019 Aug 31.
|
| 390 |
Nitric Oxide Is Involved in Activation of Toll-Like Receptor 4 Signaling through Tyrosine Nitration of Src Homology Protein Tyrosine Phosphatase 2 in Murine Dextran Sulfate-Induced Colitis.Biol Pharm Bull. 2018;41(12):1843-1852. doi: 10.1248/bpb.b18-00558.
|
| 391 |
The ESRP1-GPR137 axis contributes to intestinal pathogenesis.Elife. 2017 Oct 4;6:e28366. doi: 10.7554/eLife.28366.
|
| 392 |
Identification of FAM3D as a new endogenous chemotaxis agonist for the formyl peptide receptors.J Cell Sci. 2016 May 1;129(9):1831-42. doi: 10.1242/jcs.183053. Epub 2016 Mar 10.
|
| 393 |
Chronic colitis due to an epithelial barrier defect: the role of kindlin-1 isoforms.J Pathol. 2007 Dec;213(4):462-70. doi: 10.1002/path.2253.
|
| 394 |
FOXE1 and SYNE1 genes hypermethylation panel as promising biomarker in colitis-associated colorectal neoplasia.Inflamm Bowel Dis. 2014 Feb;20(2):271-7. doi: 10.1097/01.MIB.0000435443.07237.ed.
|
| 395 |
FoxO4 inhibits NF-kappaB and protects mice against colonic injury and inflammation.Gastroenterology. 2009 Oct;137(4):1403-14. doi: 10.1053/j.gastro.2009.06.049. Epub 2009 Jun 26.
|
| 396 |
Role of far upstream element binding protein 1 in colonic epithelial disruption during dextran sulphate sodium-induced murine colitis.Int J Clin Exp Pathol. 2014 Apr 15;7(5):2019-31. eCollection 2014.
|
| 397 |
Gab2 and Gab3 Redundantly Suppress Colitis by Modulating Macrophage and CD8(+) T-Cell Activation.Front Immunol. 2019 Mar 18;10:486. doi: 10.3389/fimmu.2019.00486. eCollection 2019.
|
| 398 |
Growth differentiation factor 11 ameliorates experimental colitis by inhibiting NLRP3 inflammasome activation.Am J Physiol Gastrointest Liver Physiol. 2018 Dec 1;315(6):G909-G920. doi: 10.1152/ajpgi.00159.2018. Epub 2018 Sep 6.
|
| 399 |
The GTPase-activating protein GIT2 protects against colitis by negatively regulating Toll-like receptor signaling.Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8883-8. doi: 10.1073/pnas.1309218111. Epub 2014 May 30.
|
| 400 |
Whole-exome sequencing reveals GPIHBP1 mutations in infantile colitis with severe hypertriglyceridemia.J Pediatr Gastroenterol Nutr. 2014 Jul;59(1):17-21. doi: 10.1097/MPG.0000000000000363.
|
| 401 |
Role and species-specific expression of colon T cell homing receptor GPR15 in colitis.Nat Immunol. 2015 Feb;16(2):207-213. doi: 10.1038/ni.3079. Epub 2014 Dec 22.
|
| 402 |
Elevation of GPRC5A expression in colorectal cancer promotes tumor progression through VNN-1 induced oxidative stress.Int J Cancer. 2017 Jun 15;140(12):2734-2747. doi: 10.1002/ijc.30698. Epub 2017 Apr 3.
|
| 403 |
Intestinal disease in Hermansky-Pudlak syndrome: occurrence of colitis and relation to genotype.Clin Gastroenterol Hepatol. 2006 Jan;4(1):73-80. doi: 10.1016/s1542-3565(05)00858-x.
|
| 404 |
Hermansky-Pudlak syndrome type 4 (HPS-4): clinical and molecular characteristics. Hum Genet. 2003 Jul;113(1):10-7. doi: 10.1007/s00439-003-0933-5. Epub 2003 Mar 27.
|
| 405 |
Elongated Flexuous Plant Virus-Derived Nanoparticles Functionalized for Autoantibody Detection.Nanomaterials (Basel). 2019 Oct 10;9(10):1438. doi: 10.3390/nano9101438.
|
| 406 |
Protective mucosal immunity mediated by epithelial CD1d and IL-10.Nature. 2014 May 22;509(7501):497-502. doi: 10.1038/nature13150. Epub 2014 Apr 6.
|
| 407 |
Inhibition of HtrA2 alleviated dextran sulfate sodium (DSS)-induced colitis by preventing necroptosis of intestinal epithelial cells.Cell Death Dis. 2019 Apr 24;10(5):344. doi: 10.1038/s41419-019-1580-7.
|
| 408 |
Platelet hyaluronidase-2 regulates the early stages of inflammatory disease in colitis.Blood. 2019 Aug 29;134(9):765-775. doi: 10.1182/blood.2018893594. Epub 2019 Jul 1.
|
| 409 |
Modulation of nuclear factor E2-related factor-2 (Nrf2) activation by the stress response gene immediate early response-3 (IER3) in colonic epithelial cells: a novel mechanism of cellular adaption to inflammatory stress.J Biol Chem. 2014 Jan 24;289(4):1917-29. doi: 10.1074/jbc.M113.490920. Epub 2013 Dec 5.
|
| 410 |
The anti-inflammatory IFITM genes ameliorate colitis and partially protect from tumorigenesis by changing immunity and microbiota.Immunol Cell Biol. 2018 Mar;96(3):284-297. doi: 10.1111/imcb.12000. Epub 2018 Jan 22.
|
| 411 |
A fumigaclavine C isostere alleviates Th1-mediated experimental colitis via competing with IFN- for binding to IFN- receptor 1.Biochem Pharmacol. 2017 Jan 1;123:63-72. doi: 10.1016/j.bcp.2016.10.004. Epub 2016 Oct 14.
|
| 412 |
Activation of Epithelial Signal Transducer and Activator of Transcription 1 by Interleukin 28 Controls Mucosal Healing inMice With Colitis and Is Increased in Mucosa of Patients WithInflammatory Bowel Disease.Gastroenterology. 2017 Jul;153(1):123-138.e8. doi: 10.1053/j.gastro.2017.03.015. Epub 2017 Mar 23.
|
| 413 |
Transplantation from a symptomatic carrier sister restores host defenses but does not prevent colitis in NEMO deficiency.Clin Immunol. 2016 Mar;164:52-6. doi: 10.1016/j.clim.2016.01.010. Epub 2016 Jan 23.
|
| 414 |
Tryptophan metabolite activation of the aryl hydrocarbon receptor regulates IL-10 receptor expression on intestinal epithelia.Mucosal Immunol. 2017 Sep;10(5):1133-1144. doi: 10.1038/mi.2016.133. Epub 2017 Jan 18.
|
| 415 |
Interleukin-17 inhibition: role in psoriasis and inflammatory bowel disease.J Dermatolog Treat. 2018 Feb;29(1):13-18. doi: 10.1080/09546634.2017.1329511. Epub 2017 May 31.
|
| 416 |
Distinct expression of interleukin (IL)-36, and , their antagonist IL-36Ra and IL-38 in psoriasis, rheumatoid arthritis and Crohn's disease.Clin Exp Immunol. 2016 May;184(2):159-73. doi: 10.1111/cei.12761. Epub 2016 Feb 22.
|
| 417 |
IL10R2 Overexpression Promotes IL22/STAT3 Signaling in Colorectal Carcinogenesis.Cancer Immunol Res. 2015 Nov;3(11):1227-35. doi: 10.1158/2326-6066.CIR-15-0031. Epub 2015 Jun 30.
|
| 418 |
TH9 cells that express the transcription factor PU.1 drive T cell-mediated colitis via IL-9 receptor signaling in intestinal epithelial cells.Nat Immunol. 2014 Jul;15(7):676-86. doi: 10.1038/ni.2920. Epub 2014 Jun 8.
|
| 419 |
IQ Motif-Containing GTPase-Activating Protein 2 (IQGAP2) Is a Novel Regulator of Colonic Inflammation in Mice.PLoS One. 2015 Jun 5;10(6):e0129314. doi: 10.1371/journal.pone.0129314. eCollection 2015.
|
| 420 |
Reducing IRF5 expression attenuates colitis in mice, but impairs the clearance of intestinal pathogens.Mucosal Immunol. 2019 Jul;12(4):874-887. doi: 10.1038/s41385-019-0165-1. Epub 2019 May 3.
|
| 421 |
IRGM restrains NLRP3 inflammasome activation by mediating its SQSTM1/p62-dependent selective autophagy.Autophagy. 2019 Sep;15(9):1645-1647. doi: 10.1080/15548627.2019.1628544. Epub 2019 Jun 20.
|
| 422 |
Serum-Derived Hyaluronan-Associated Protein Is a Novel Biomarker for Inflammatory Bowel Diseases.Digestion. 2017;95(2):146-155. doi: 10.1159/000456071. Epub 2017 Feb 4.
|
| 423 |
MiR-155 contributes to Th17 cells differentiation in dextran sulfate sodium (DSS)-induced colitis mice via Jarid2.Biochem Biophys Res Commun. 2017 Jun 17;488(1):6-14. doi: 10.1016/j.bbrc.2017.04.143. Epub 2017 Apr 28.
|
| 424 |
KDM2B promotes IL-6 production and inflammatory responses through Brg1-mediated chromatin remodeling.Cell Mol Immunol. 2020 Aug;17(8):834-842. doi: 10.1038/s41423-019-0251-z. Epub 2019 Jun 13.
|
| 425 |
Layilin is critical for mediating hyaluronan 35kDa-induced intestinal epithelial tight junction protein ZO-1 in vitro and in vivo.Matrix Biol. 2018 Mar;66:93-109. doi: 10.1016/j.matbio.2017.09.003. Epub 2017 Oct 1.
|
| 426 |
Chloride channel ClC-2 is a key factor in the development of DSS-induced murine colitis.Inflamm Bowel Dis. 2013 Dec;19(13):2867-77. doi: 10.1097/MIB.0b013e3182a82ae9.
|
| 427 |
TFF3 interacts with LINGO2 to regulate EGFR activation for protection against colitis and gastrointestinal helminths.Nat Commun. 2019 Sep 27;10(1):4408. doi: 10.1038/s41467-019-12315-1.
|
| 428 |
Serum leucine-rich alpha-2 glycoprotein is a disease activity biomarker in ulcerative colitis.Inflamm Bowel Dis. 2012 Nov;18(11):2169-79. doi: 10.1002/ibd.22936. Epub 2012 Feb 28.
|
| 429 |
Inhibition of myeloid differentiation 1 specifically in colon with antisense oligonucleotide exacerbates dextran sodium sulfate-induced colitis.J Cell Biochem. 2019 Oct;120(10):16888-16899. doi: 10.1002/jcb.28947. Epub 2019 May 19.
|
| 430 |
ACF7 regulates inflammatory colitis and intestinal wound response by orchestrating tight junction dynamics.Nat Commun. 2017 May 25;8:15375. doi: 10.1038/ncomms15375.
|
| 431 |
STOP-Colitis pilot trial protocol: a prospective, open-label, randomised pilot study to assess two possible routes of faecal microbiota transplant delivery in patients with ulcerative colitis.BMJ Open. 2019 Nov 11;9(11):e030659. doi: 10.1136/bmjopen-2019-030659.
|
| 432 |
DNA Methylation of miR-122 Aggravates Oxidative Stress in Colitis Targeting SELENBP1 Partially by p65NF-B Signaling.Oxid Med Cell Longev. 2019 Mar 24;2019:5294105. doi: 10.1155/2019/5294105. eCollection 2019.
|
| 433 |
TNF--induced down-regulation of CDX2 suppresses MEP1A expression in colitis.Biochim Biophys Acta. 2012 Jun;1822(6):843-51. doi: 10.1016/j.bbadis.2012.01.012. Epub 2012 Feb 3.
|
| 434 |
MFSD2A Promotes Endothelial Generation of Inflammation-Resolving Lipid Mediators and Reduces ColitisinMice.Gastroenterology. 2017 Nov;153(5):1363-1377.e6. doi: 10.1053/j.gastro.2017.07.048. Epub 2017 Aug 4.
|
| 435 |
Mesenchymal stromal cells-derived matrix Gla protein contribute to the alleviation of experimental colitis.Cell Death Dis. 2018 Jun 7;9(6):691. doi: 10.1038/s41419-018-0734-3.
|
| 436 |
MMP-19 deficiency causes aggravation of colitis due to defects in innate immune cell function.Mucosal Immunol. 2016 Jul;9(4):974-85. doi: 10.1038/mi.2015.117. Epub 2015 Nov 11.
|
| 437 |
Cellular sources of MMP-7, MMP-13 and MMP-28 in ulcerative colitis.Scand J Gastroenterol. 2010 Oct;45(10):1186-96. doi: 10.3109/00365521.2010.499961.
|
| 438 |
RIP3 deficiency exacerbates inflammation in dextran sodium sulfate-induced ulcerative colitis mice model.Cell Biochem Funct. 2017 Apr;35(3):156-163. doi: 10.1002/cbf.3257. Epub 2017 Mar 2.
|
| 439 |
MKL1 expressed in macrophages contributes to the development of murine colitis.Sci Rep. 2017 Oct 20;7(1):13650. doi: 10.1038/s41598-017-13629-0.
|
| 440 |
The PSMP-CCR2 interactions trigger monocyte/macrophage-dependent colitis.Sci Rep. 2017 Jul 11;7(1):5107. doi: 10.1038/s41598-017-05255-7.
|
| 441 |
The class I myosin MYO1D binds to lipid and protects against colitis.Dis Model Mech. 2018 Sep 27;11(9):dmm035923. doi: 10.1242/dmm.035923.
|
| 442 |
Ndfip1 restricts Th17 cell potency by limiting lineage stability and proinflammatory cytokine production.Sci Rep. 2017 Jan 4;7:39649. doi: 10.1038/srep39649.
|
| 443 |
Context-dependent regulation of Th17-associated genes and IFN expression by the transcription factor NFAT5.Immunol Cell Biol. 2017 Jan;95(1):56-67. doi: 10.1038/icb.2016.69. Epub 2016 Aug 1.
|
| 444 |
Cytosolic flagellin receptor NLRC4 protects mice against mucosal and systemic challenges.Mucosal Immunol. 2012 May;5(3):288-98. doi: 10.1038/mi.2012.8. Epub 2012 Feb 8.
|
| 445 |
NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth.Nat Immunol. 2017 May;18(5):541-551. doi: 10.1038/ni.3690. Epub 2017 Mar 13.
|
| 446 |
Nuclear orphan receptor NR2F6 as a safeguard against experimental murine colitis.Gut. 2018 Aug;67(8):1434-1444. doi: 10.1136/gutjnl-2016-313466. Epub 2017 Aug 4.
|
| 447 |
Effects of humanin on experimental colitis induced by 2,4,6-trinitrobenzene sulphonic acid in rats.Saudi J Gastroenterol. 2017 Mar-Apr;23(2):105-111. doi: 10.4103/sjg.SJG_318_16.
|
| 448 |
Elevated O-GlcNAcylation promotes colonic inflammation and tumorigenesis by modulating NF-B signaling.Oncotarget. 2015 May 20;6(14):12529-42. doi: 10.18632/oncotarget.3725.
|
| 449 |
Optineurin deficiency in mice contributes to impaired cytokine secretion and neutrophil recruitment in bacteria-driven colitis.Dis Model Mech. 2015 Aug 1;8(8):817-29. doi: 10.1242/dmm.020362. Epub 2015 Jun 4.
|
| 450 |
Peptide Hp(2-20) accelerates healing of TNBS-induced colitis in the rat.United European Gastroenterol J. 2018 Nov;6(9):1428-1436. doi: 10.1177/2050640618793564. Epub 2018 Aug 24.
|
| 451 |
Upregulation of miR-665 promotes apoptosis and colitis in inflammatory bowel disease by repressing the endoplasmic reticulum stress components XBP1 and ORMDL3.Cell Death Dis. 2017 Mar 23;8(3):e2699. doi: 10.1038/cddis.2017.76.
|
| 452 |
Loss of PACS-2 delays regeneration in DSS-induced colitis but does not affect the Apc(Min) model of colorectal cancer.Oncotarget. 2017 Nov 26;8(65):108303-108315. doi: 10.18632/oncotarget.22661. eCollection 2017 Dec 12.
|
| 453 |
Unexpected role of anticoagulant protein C in controlling epithelial barrier integrity and intestinal inflammation.Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):19830-5. doi: 10.1073/pnas.1107140108. Epub 2011 Nov 22.
|
| 454 |
BMI1 and MEL18 Promote Colitis-Associated Cancer inMiceviaREG3B and STAT3.Gastroenterology. 2017 Dec;153(6):1607-1620. doi: 10.1053/j.gastro.2017.07.044. Epub 2017 Aug 3.
|
| 455 |
PGlyRP3 concerts with PPAR to attenuate DSS-induced colitis in mice.Int Immunopharmacol. 2019 Feb;67:46-53. doi: 10.1016/j.intimp.2018.12.005. Epub 2018 Dec 7.
|
| 456 |
Cooperative role of NF-{kappa}B and poly(ADP-ribose) polymerase 1 (PARP-1) in the TNF-induced inhibition of PHEX expression in osteoblasts.J Biol Chem. 2010 Nov 5;285(45):34828-38. doi: 10.1074/jbc.M110.152868. Epub 2010 Sep 3.
|
| 457 |
Modifying the protease, antiprotease pattern by elafin overexpression protects mice from colitis.Gastroenterology. 2011 Apr;140(4):1272-82. doi: 10.1053/j.gastro.2010.12.050. Epub 2011 Jan 1.
|
| 458 |
Contribution of polymeric immunoglobulin receptor to regulation of intestinal inflammation in dextran sulfate sodium-induced colitis.J Gastroenterol Hepatol. 2006 Sep;21(9):1372-80. doi: 10.1111/j.1440-1746.2006.04312.x.
|
| 459 |
FAM64A positively regulates STAT3 activity to promote Th17 differentiation and colitis-associated carcinogenesis.Proc Natl Acad Sci U S A. 2019 May 21;116(21):10447-10452. doi: 10.1073/pnas.1814336116. Epub 2019 May 6.
|
| 460 |
Induction of PIR-A/B(+) DCs in the in vitro inflammatory condition and their immunoregulatory function.J Gastroenterol. 2018 Oct;53(10):1131-1141. doi: 10.1007/s00535-018-1447-1. Epub 2018 Mar 5.
|
| 461 |
Colitis promotes neuronal differentiation of Sox2+ and PLP1+ enteric cells.Sci Rep. 2017 May 31;7(1):2525. doi: 10.1038/s41598-017-02890-y.
|
| 462 |
Calcineurin-mediated IL-2 production by CD11c(high)MHCII(+) myeloid cells is crucial for intestinal immune homeostasis.Nat Commun. 2018 Mar 16;9(1):1102. doi: 10.1038/s41467-018-03495-3.
|
| 463 |
Prdx6 Deficiency Ameliorates DSS Colitis: Relevance of Compensatory Antioxidant Mechanisms.J Crohns Colitis. 2017 Jul 1;11(7):871-884. doi: 10.1093/ecco-jcc/jjx016.
|
| 464 |
The thymus-specific serine protease TSSP/PRSS16 is crucial for the antitumoral role of CD4(+) T cells.Cell Rep. 2015 Jan 6;10(1):39-46. doi: 10.1016/j.celrep.2014.12.009. Epub 2014 Dec 24.
|
| 465 |
A plant cell-expressed recombinant anti-TNF fusion protein is biologically active in the gut and alleviates immune-mediated hepatitis and colitis.Immunobiology. 2017 Mar;222(3):544-551. doi: 10.1016/j.imbio.2016.11.001. Epub 2016 Nov 4.
|
| 466 |
REG Controls Hippo Signaling and Reciprocal NF-B-YAP Regulation to Promote Colon Cancer.Clin Cancer Res. 2018 Apr 15;24(8):2015-2025. doi: 10.1158/1078-0432.CCR-17-2986. Epub 2018 Feb 6.
|
| 467 |
Enterococcus faecalis Gluconate Phosphotransferase System Accelerates Experimental Colitis and Bacterial Killing by Macrophages.Infect Immun. 2019 Jun 20;87(7):e00080-19. doi: 10.1128/IAI.00080-19. Print 2019 Jul.
|
| 468 |
Rab32-related antimicrobial pathway is involved in the progression of dextran sodium sulfate-induced colitis.FEBS Open Bio. 2018 Sep 21;8(10):1658-1668. doi: 10.1002/2211-5463.12514. eCollection 2018 Oct.
|
| 469 |
Effects of Melatonin on Intestinal Microbiota and Oxidative Stress in Colitis Mice.Biomed Res Int. 2018 Feb 6;2018:2607679. doi: 10.1155/2018/2607679. eCollection 2018.
|
| 470 |
Total CD3 T Cells Are Necessary and Sufficient to Induce Colitis in Immunodeficient Mice With Dendritic Cell-Specific Deletion of TGFbR2: A Novel IBD Model to Study CD4 and CD8 T-Cell Interaction.Inflamm Bowel Dis. 2020 Jan 6;26(2):229-241. doi: 10.1093/ibd/izz191.
|
| 471 |
Stress Response Protein RBM3 Promotes the Development of Colitis-associated Cancer.Inflamm Bowel Dis. 2017 Jan;23(1):57-65. doi: 10.1097/MIB.0000000000000968.
|
| 472 |
The AIM2 inflammasome is a central regulator of intestinal homeostasis through the IL-18/IL-22/STAT3 pathway.Cell Mol Immunol. 2017 Jan;14(1):127-142. doi: 10.1038/cmi.2016.35. Epub 2016 Aug 15.
|
| 473 |
Senescence marker protein 30 protects intestinal epithelial cells against inflammation-induced cell death by enhancing Nrf2 activity.Biochim Biophys Acta Mol Basis Dis. 2018 Dec;1864(12):3668-3678. doi: 10.1016/j.bbadis.2018.09.031. Epub 2018 Sep 26.
|
| 474 |
Loss of RNF40 Decreases NF-B Activity in Colorectal Cancer Cells and Reduces Colitis Burden in Mice.J Crohns Colitis. 2019 Mar 26;13(3):362-373. doi: 10.1093/ecco-jcc/jjy165.
|
| 475 |
Ro60 Inhibits Colonic Inflammation and Fibrosis in a Mouse Model of Dextran Sulfate Sodium-Induced Colitis.Immunol Lett. 2018 Sep;201:45-51. doi: 10.1016/j.imlet.2018.11.001. Epub 2018 Nov 3.
|
| 476 |
Maresin 1 mitigates concanavalin A-induced acute liver injury in mice by inhibiting ROS-mediated activation of NF-B signaling.Free Radic Biol Med. 2020 Feb 1;147:23-36. doi: 10.1016/j.freeradbiomed.2019.11.033. Epub 2019 Nov 27.
|
| 477 |
SR-A1 suppresses colon inflammation and tumorigenesis through negative regulation of NF-B signaling.Biochem Pharmacol. 2018 Aug;154:335-343. doi: 10.1016/j.bcp.2018.05.017. Epub 2018 May 31.
|
| 478 |
Syndecan-4 Modulates Epithelial Gut Barrier Function and Epithelial Regeneration in Experimental Colitis.Inflamm Bowel Dis. 2018 Nov 29;24(12):2579-2589. doi: 10.1093/ibd/izy248.
|
| 479 |
The role of the selenoprotein S (SELS) gene -105G>A promoter polymorphism in inflammatory bowel disease and regulation of SELS gene expression in intestinal inflammation.Tissue Antigens. 2007 Sep;70(3):238-46. doi: 10.1111/j.1399-0039.2007.00888.x.
|
| 480 |
Semaphorin 3E regulates apoptosis in the intestinal epithelium during the development of colitis.Biochem Pharmacol. 2019 Aug;166:264-273. doi: 10.1016/j.bcp.2019.05.029. Epub 2019 Jun 3.
|
| 481 |
Sphingomyelin synthase 2 deficiency inhibits the induction of murine colitis-associated colon cancer.FASEB J. 2017 Sep;31(9):3816-3830. doi: 10.1096/fj.201601225RR. Epub 2017 May 18.
|
| 482 |
Sorting nexin 10 acting as a novel regulator of macrophage polarization mediates inflammatory response in experimental mouse colitis.Sci Rep. 2016 Feb 9;6:20630. doi: 10.1038/srep20630.
|
| 483 |
Sox12 promotes T reg differentiation in the periphery during colitis.J Exp Med. 2018 Oct 1;215(10):2509-2519. doi: 10.1084/jem.20172082. Epub 2018 Sep 6.
|
| 484 |
Hookworm-Derived Metabolites Suppress Pathology in a Mouse Model of Colitis and Inhibit Secretion of Key Inflammatory Cytokines in Primary Human Leukocytes.Infect Immun. 2019 Mar 25;87(4):e00851-18. doi: 10.1128/IAI.00851-18. Print 2019 Apr.
|
| 485 |
Heme ameliorates dextran sodium sulfate-induced colitis through providing intestinal macrophages with noninflammatory profiles.Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):8418-8423. doi: 10.1073/pnas.1808426115. Epub 2018 Jul 30.
|
| 486 |
SRC-3 protects intestine from DSS-induced colitis by inhibiting inflammation and promoting goblet cell differentiation through enhancement of KLF4 expression.Int J Biol Sci. 2018 Nov 3;14(14):2051-2064. doi: 10.7150/ijbs.28576. eCollection 2018.
|
| 487 |
Quantitative proteomics identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer.Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):E9608-E9617. doi: 10.1073/pnas.1712946114. Epub 2017 Oct 23.
|
| 488 |
Overexpression of Ste20-related proline/alanine-rich kinase exacerbates experimental colitis in mice.J Immunol. 2011 Aug 1;187(3):1496-505. doi: 10.4049/jimmunol.1002910. Epub 2011 Jun 24.
|
| 489 |
MDR1 deficiency impairs mitochondrial homeostasis and promotes intestinal inflammation.Mucosal Immunol. 2018 Jan;11(1):120-130. doi: 10.1038/mi.2017.31. Epub 2017 Apr 12.
|
| 490 |
Dual functions of Rap1 are crucial for T-cell homeostasis and prevention of spontaneous colitis.Nat Commun. 2015 Dec 4;6:8982. doi: 10.1038/ncomms9982.
|
| 491 |
Therapeutic potential of adenovirus-mediated TFF2-CTP-Flag peptide for treatment of colorectal cancer.Cancer Gene Ther. 2019 Feb;26(1-2):48-57. doi: 10.1038/s41417-018-0036-z. Epub 2018 Jul 25.
|
| 492 |
Involvement of TACE in colon inflammation: a novel mechanism of regulation via SIRT-1 activation.Cytokine. 2014 Mar;66(1):30-9. doi: 10.1016/j.cyto.2013.12.010. Epub 2014 Jan 4.
|
| 493 |
TMEM258 Is a Component of the Oligosaccharyltransferase Complex Controlling ER Stress and Intestinal Inflammation.Cell Rep. 2016 Dec 13;17(11):2955-2965. doi: 10.1016/j.celrep.2016.11.042.
|
| 494 |
Exacerbated experimental colitis in TNFAIP8-deficient mice.J Immunol. 2015 Jun 15;194(12):5736-42. doi: 10.4049/jimmunol.1401986. Epub 2015 May 6.
|
| 495 |
CD30 ligand is a target for a novel biological therapy against colitis associated with Th17 responses.J Immunol. 2010 Dec 15;185(12):7671-80. doi: 10.4049/jimmunol.1002229. Epub 2010 Nov 10.
|
| 496 |
Toll-interacting protein modulates colitis susceptibility in mice.Inflamm Bowel Dis. 2014 Apr;20(4):660-70. doi: 10.1097/MIB.0000000000000006.
|
| 497 |
Importance of mast cell Prss31/transmembrane tryptase/tryptase- in lung function and experimental chronic obstructive pulmonary disease and colitis.J Biol Chem. 2014 Jun 27;289(26):18214-27. doi: 10.1074/jbc.M114.548594. Epub 2014 May 12.
|
| 498 |
Up-regulation and pre-activation of TRAF3 and TRAF5 in inflammatory bowel disease.Int J Med Sci. 2013;10(2):156-63. doi: 10.7150/ijms.5457. Epub 2013 Jan 3.
|
| 499 |
Association of TRAP1 with infliximab-induced mucosal healing in Crohn's disease.J Gastroenterol Hepatol. 2019 Dec;34(12):2118-2125. doi: 10.1111/jgh.14696. Epub 2019 Jun 18.
|
| 500 |
SARI suppresses colitis-associated cancer development by maintaining MCP-1-mediated tumour-associated macrophage recruitment.J Cell Mol Med. 2020 Jan;24(1):189-201. doi: 10.1111/jcmm.14699. Epub 2019 Oct 2.
|
| 501 |
Ten years of research on the role of BVES/ POPDC1 in human disease: a review.Onco Targets Ther. 2019 Feb 18;12:1279-1291. doi: 10.2147/OTT.S192364. eCollection 2019.
|
| 502 |
CD1d Modulates Colonic Inflammation in NOD2-/- Mice by Altering the Intestinal Microbial Composition Comprising Acetatifactor muris.J Crohns Colitis. 2019 Aug 14;13(8):1081-1091. doi: 10.1093/ecco-jcc/jjz025.
|
| 503 |
Chromogranin-A Regulates Macrophage Function and the Apoptotic Pathway in Murine DSS colitis.J Mol Med (Berl). 2018 Feb;96(2):183-198. doi: 10.1007/s00109-017-1613-6. Epub 2017 Dec 22.
|
| 504 |
Pharmacological inhibition of GPR4 remediates intestinal inflammation in a mouse colitis model.Eur J Pharmacol. 2019 Jun 5;852:218-230. doi: 10.1016/j.ejphar.2019.03.038. Epub 2019 Mar 28.
|
| 505 |
A20 in dendritic cells restrains intestinal anti-bacterial peptide expression and preserves commensal homeostasis.PLoS One. 2019 Jul 11;14(7):e0218999. doi: 10.1371/journal.pone.0218999. eCollection 2019.
|
| 506 |
Pyrin Inflammasome Regulates Tight Junction Integrity toRestrict Colitis and Tumorigenesis.Gastroenterology. 2018 Mar;154(4):948-964.e8. doi: 10.1053/j.gastro.2017.11.276. Epub 2017 Dec 2.
|
| 507 |
NFIL3 is a regulator of IL-12 p40 in macrophages and mucosal immunity.J Immunol. 2011 Apr 15;186(8):4649-55. doi: 10.4049/jimmunol.1003888. Epub 2011 Mar 7.
|
| 508 |
Host NLRP6 exacerbates graft-versus-host disease independent of gut microbial composition.Nat Microbiol. 2019 May;4(5):800-812. doi: 10.1038/s41564-019-0373-1. Epub 2019 Mar 11.
|
| 509 |
Protective Effect of Methane-Rich Saline on Acetic Acid-Induced Ulcerative Colitis via Blocking the TLR4/NF-B/MAPK Pathway and Promoting IL-10/JAK1/STAT3-Mediated Anti-inflammatory Response.Oxid Med Cell Longev. 2019 Apr 28;2019:7850324. doi: 10.1155/2019/7850324. eCollection 2019.
|
| 510 |
Loss of Smad5 leads to the disassembly of the apical junctional complex and increased susceptibility to experimental colitis.Am J Physiol Gastrointest Liver Physiol. 2011 Apr;300(4):G586-97. doi: 10.1152/ajpgi.00041.2010. Epub 2011 Jan 6.
|
|
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|
|
|
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