General Information of Disease (ID: DISD51WR)

Disease Name Lung adenocarcinoma
Synonyms non-small cell lung adenocarcinoma; adenocarcinoma of the lung; bronchogenic lung adenocarcinoma; adenocarcinoma of lung; nonsmall cell adenocarcinoma; lung adenocarcinoma
Definition
A carcinoma that arises from the lung and is characterized by the presence of malignant glandular epithelial cells. There is a male predilection with a male to female ratio of 2:1. Usually lung adenocarcinoma is asymptomatic and is identified through screening studies or as an incidental radiologic finding. If clinical symptoms are present they include shortness of breath, cough, hemoptysis, chest pain, and fever. Tobacco smoke is a known risk factor.
Disease Hierarchy
DIS5Y6R9: Non-small-cell lung cancer
DIS3IHTY: Adenocarcinoma
DISD51WR: Lung adenocarcinoma
Disease Identifiers
MONDO ID
MONDO_0005061
MESH ID
D000077192
UMLS CUI
C0152013
MedGen ID
57744
HPO ID
HP:0030078
Orphanet ID
415268
SNOMED CT ID
254626006

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 3 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Bevacizumab DMSD1UN Approved Monoclonal antibody [1]
Carboplatin DMG281S Approved Small molecular drug [2]
Paclitaxel DMLB81S Approved Small molecular drug [3]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 506 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
ALOX12B TTQ4QQH Limited Biomarker [4]
ALOX5 TTSJ6Q4 Limited Biomarker [4]
ANXA5 TT2Z83I Limited Biomarker [5]
ASPH TT2KHP7 Limited Biomarker [6]
ATR TT8ZYBQ Limited Altered Expression [7]
CDC25A TTLZS4Q Limited Biomarker [8]
CDK4 TT0PG8F Limited Biomarker [9]
CYP2A6 TTAQ6ZW Limited Genetic Variation [10]
DEPDC1 TT8S9CM Limited Altered Expression [11]
EPOR TTAUX24 Limited Altered Expression [12]
FGF7 TTFY134 Limited Genetic Variation [10]
FGFR4 TT1KX2S Limited Biomarker [13]
GABRA3 TT37EDJ Limited Altered Expression [14]
GAPDH TTUGSWA Limited Altered Expression [15]
GDF15 TT4MXVG Limited Altered Expression [16]
GDF2 TTAP4T1 Limited Biomarker [17]
GIP TT40HS5 Limited Biomarker [18]
KCNK3 TTGR91N Limited Altered Expression [19]
LCK TT860QF Limited Biomarker [20]
LDHA TTW76JE Limited Biomarker [21]
MTAP TTDBX7N Limited Genetic Variation [10]
MYLK2 TTHLGB2 Limited Genetic Variation [22]
NCL TTK1V5Q Limited Biomarker [23]
P2RY12 TTZ1DT0 Limited Biomarker [24]
P2RY6 TTNVSKA Limited Biomarker [24]
PCSK9 TTNIZ2B Limited Biomarker [25]
PDK1 TTCZOF2 Limited Posttranslational Modification [26]
PGR TTUV8G9 Limited Biomarker [27]
RAF1 TTAN5W2 Limited Genetic Variation [28]
RASA1 TTPNZ1F Limited Biomarker [29]
SLC38A1 TT1YE9Z Limited Altered Expression [19]
TACSTD2 TTP2HE5 Limited Altered Expression [30]
TNK2 TTIET93 Limited Altered Expression [31]
WEE1 TTJFOAL Limited Biomarker [32]
WNK1 TTJ9UMX Limited Biomarker [33]
ARRB2 TT8SO2I Disputed Altered Expression [34]
CYP1A2 TTS1DTU Disputed Genetic Variation [35]
DDR2 TTU98HG Disputed Genetic Variation [36]
DSG3 TTEO4P8 Disputed Biomarker [37]
EPHA5 TTV9KOD Disputed Genetic Variation [38]
FLT1 TT1VAUK Disputed Altered Expression [39]
KEAP1 TT3Z6Y9 Disputed Genetic Variation [40]
KRT6A TT2FX8W Disputed Biomarker [37]
NTRK2 TTKN7QR Disputed Biomarker [41]
NTRK3 TTXABCW Disputed Genetic Variation [42]
PRKDC TTK3PY9 Disputed Biomarker [43]
RRM2 TT1S4LJ Disputed Biomarker [23]
ABCC3 TTVLG21 moderate Biomarker [44]
ADRB1 TTR6W5O moderate Biomarker [45]
AIMP2 TTXWHGF moderate Altered Expression [46]
ALCAM TT2AFT6 moderate Altered Expression [47]
ANG TTURHFP moderate Altered Expression [48]
ARAF TT5TURO moderate Genetic Variation [28]
AXL TTZPY6J moderate Altered Expression [49]
BMI1 TTIPNSR moderate Biomarker [50]
BRAF TT0EOB8 moderate Biomarker [51]
CD24 TTCTYNP moderate Biomarker [52]
CD80 TT89Z17 moderate Altered Expression [53]
CDK1 TTH6V3D moderate Altered Expression [54]
CEACAM3 TTPX7I5 moderate Biomarker [55]
CEBPB TTUI35N moderate Altered Expression [56]
CHRNA4 TT4H1MQ moderate Altered Expression [57]
CLCN3 TT8XNZ7 moderate Altered Expression [58]
COL1A2 TTUABC1 moderate Biomarker [59]
CPS1 TT42M75 moderate Altered Expression [60]
CTAG1A TTE5ITK moderate Biomarker [61]
CTSD TTPT2QI moderate Biomarker [62]
CYP1B1 TTI84H7 moderate Genetic Variation [63]
DDR1 TTI1FPZ moderate Biomarker [64]
DKK3 TTY2ZV6 moderate Biomarker [65]
DLK1 TTF4AVB moderate Altered Expression [66]
EPAS1 TTWPA54 moderate Biomarker [9]
ESRRB TTKF0XS moderate Altered Expression [67]
EYA2 TTUY9C6 moderate Altered Expression [68]
F11R TT3C8EG moderate Altered Expression [69]
FLT4 TTDCBX5 moderate Biomarker [70]
FOLR1 TTVC37M moderate Altered Expression [71]
FUT4 TTNV1KZ moderate Altered Expression [72]
GAS6 TT69QD2 moderate Altered Expression [73]
GPC3 TTJTSX4 moderate Altered Expression [74]
GRB2 TTEYRJ9 moderate Biomarker [75]
GSN TTUH7OM moderate Altered Expression [76]
GZMB TTKEPHX moderate Biomarker [77]
IKBKB TTJ3E9X moderate Genetic Variation [78]
IL12RB2 TT4SWR8 moderate Genetic Variation [79]
IMP3 TTEJA2R moderate Biomarker [80]
INHBA TTVB30D moderate Genetic Variation [81]
IRS1 TTAJSQ0 moderate Biomarker [82]
MAP3K3 TTJZNIG moderate Altered Expression [83]
MAP4K4 TT6NI13 moderate Biomarker [84]
MBTPS1 TTNSM2I moderate Altered Expression [85]
MIA TT5HNVS moderate Biomarker [86]
MMP10 TTXLEG7 moderate Biomarker [87]
MMP15 TTNSTO3 moderate Altered Expression [88]
MSLN TT4RXME moderate Altered Expression [89]
MTTP TTUS1RD moderate Biomarker [90]
NCOA3 TT124R0 moderate Altered Expression [91]
NECTIN4 TTPO9EG moderate Biomarker [92]
NEDD4 TT1QU6G moderate Altered Expression [93]
NEK2 TT3VZ24 moderate Altered Expression [94]
NRAS TTW2R9X moderate Genetic Variation [28]
PAK1 TTFN95D moderate Biomarker [95]
PBK TTMY6BZ moderate Altered Expression [96]
PDCD2 TTYOVWN moderate Altered Expression [97]
PLA2G2A TTO8QRU moderate Biomarker [98]
PRKCI TTWJTHX moderate Biomarker [99]
RAC3 TT9BQ50 moderate Altered Expression [100]
ROCK1 TTZN7RP moderate Biomarker [101]
ROS1 TTSZ6Y3 moderate Biomarker [102]
S1PR1 TT9JZCK moderate Biomarker [103]
SCGB1A1 TTONPVW moderate Genetic Variation [104]
SCT TTOBVIN moderate Biomarker [105]
SELP TTE5VG0 moderate Altered Expression [106]
SETD2 TTPC3H4 moderate Altered Expression [107]
SLC7A11 TTBZMIO moderate Biomarker [108]
SLIT2 TTDWK85 moderate Biomarker [109]
STRAP TT165DP moderate Biomarker [110]
TACC3 TTQ4UFD moderate Genetic Variation [111]
TAGLN TTDRZ9H moderate Altered Expression [112]
TFAP2A TTDY4BS moderate Biomarker [113]
TRAF6 TTCDR6M moderate Altered Expression [114]
USP14 TTVSYP9 moderate Biomarker [115]
VIPR1 TTCL30I moderate Altered Expression [116]
ABCC1 TTOI92F Strong Biomarker [117]
ABCG1 TTMWDGU Strong Biomarker [118]
ABL2 TT1A6HL Strong Biomarker [119]
ACVR1B TTPKHTZ Strong Genetic Variation [120]
ADAM17 TT6AZXG Strong Biomarker [121]
ADORA2A TTM2AOE Strong Altered Expression [122]
AGR2 TT9K86S Strong Altered Expression [123]
AHCY TTE2KUJ Strong Biomarker [23]
AHR TT037IE Strong Altered Expression [124]
AKT1 TTWTSCV Strong Altered Expression [125]
AKT2 TTH24WI Strong Biomarker [126]
ALB TTFNGC9 Strong Biomarker [127]
ALKBH5 TTOHB1M Strong Biomarker [128]
ALOX5AP TTDMBF5 Strong Altered Expression [129]
AMOT TTI48OS Strong Biomarker [130]
ANTXR2 TTOD34I Strong Genetic Variation [131]
ANXA1 TTUCK4B Strong Biomarker [132]
APC2 TTSMK36 Strong Biomarker [133]
APOA1 TT5S8DR Strong Biomarker [127]
AQP3 TTLDNMQ Strong Altered Expression [134]
ARRB1 TTMVD4A Strong Altered Expression [135]
ASAP3 TTB4ZEN Strong Biomarker [136]
ATF4 TTQCKWT Strong Biomarker [137]
ATXN2 TTPQJ7P Strong Genetic Variation [138]
AURKA TTPS3C0 Strong Altered Expression [139]
AURKB TT9RTBL Strong Altered Expression [140]
AZGP1 TTUPYLV Strong Altered Expression [141]
B2M TTY7FKA Strong Genetic Variation [28]
BCL11A TTR61MW Strong Biomarker [142]
BGN TT0JPVF Strong Biomarker [143]
BPI TTXCSDR Strong Biomarker [144]
BRCA2 TTUARD6 Strong Genetic Variation [145]
BRD7 TT07ZS1 Strong Altered Expression [146]
CA12 TTSYM0R Strong Biomarker [147]
CACNA1C TTZIFHC Strong Altered Expression [148]
CCNA2 TTAMQ62 Strong Biomarker [149]
CCR3 TTD3XFU Strong Altered Expression [150]
CD200 TT0BE68 Strong Biomarker [151]
CD44 TTWFBT7 Strong Genetic Variation [152]
CD69 TTPQE9F Strong Altered Expression [153]
CDC25C TTESBNC Strong Altered Expression [154]
CDC7 TTSMTDI Strong Biomarker [155]
CDH1 TTLAWO6 Strong Altered Expression [156]
CDH2 TT1WS0T Strong Biomarker [157]
CDH3 TTARMD9 Strong Altered Expression [94]
CDK5R1 TTBYM6V Strong Altered Expression [158]
CEACAM6 TTIGH2W Strong Biomarker [159]
CENPE TTZD5QR Strong Biomarker [160]
CFB TTA0P7K Strong Genetic Variation [161]
CFI TT6ATLX Strong Biomarker [162]
CHEK1 TTTU902 Strong Altered Expression [163]
CHPF TTAZB7S Strong Altered Expression [164]
CHRNA5 TTH2QRX Strong Genetic Variation [10]
CHRNA7 TTLA931 Strong Biomarker [165]
CHRNB4 TTTVAFQ Strong Genetic Variation [10]
CHUK TT1F8OQ Strong Biomarker [78]
CLCF1 TTI6V13 Strong Biomarker [166]
CLDN4 TTMTS9H Strong Altered Expression [167]
CMA1 TT8VUE0 Strong Biomarker [168]
CNTFR TTT2F9E Strong Biomarker [166]
COPS5 TTSTNJR Strong Biomarker [169]
CPM TTVOH2M Strong Biomarker [170]
CREBBP TTFRCTK Strong Biomarker [171]
CTNNB1 TTRPKQG Strong Genetic Variation [172]
CTSA TT5NILS Strong Altered Expression [173]
CTSE TTLXC4Q Strong Altered Expression [174]
CUL3 TTPCU0Q Strong Altered Expression [175]
CYP21A2 TTP4GLG Strong Genetic Variation [161]
CYP24A1 TT82UI1 Strong Biomarker [176]
CYP3A5 TTHS0OK Strong Biomarker [177]
DDIT4 TTVEOY6 Strong Biomarker [178]
DEPTOR TTLYP6D Strong Biomarker [179]
DKK1 TTE3RAC Strong Biomarker [180]
DLL3 TT1C9K6 Strong Altered Expression [181]
DNMT3A TTJUALD Strong Genetic Variation [28]
DOT1L TTSZ8T1 Strong Biomarker [29]
DTL TT8396I Strong Altered Expression [182]
E2F3 TTWIJYH Strong Altered Expression [183]
EED TTFNJ4R Strong Biomarker [184]
EEF2K TT1QFLA Strong Biomarker [185]
EGF TTED8JB Strong Altered Expression [186]
EGFL6 TTXJGAR Strong Altered Expression [187]
EGLN1 TT9ISBX Strong Biomarker [188]
EGLN2 TTMHFRY Strong Posttranslational Modification [189]
EIF4E TTZGCP6 Strong Biomarker [171]
EIF5A TTIVCNR Strong Biomarker [190]
EPCAM TTZ8WH4 Strong Altered Expression [47]
EPHA1 TTLFZVU Strong Altered Expression [191]
EPHA3 TTHS2LR Strong Genetic Variation [192]
EPHA4 TTG84D3 Strong Altered Expression [191]
EPHA8 TTHZ2LW Strong Biomarker [13]
EPHB1 TT8MDAC Strong Genetic Variation [193]
EPHB2 TTKPV6O Strong Biomarker [194]
EPHB6 TTZEMUY Strong Altered Expression [195]
EPX TTCIO0M Strong Altered Expression [196]
ERBB3 TTSINU2 Strong Altered Expression [197]
ESRRA TTPNQAC Strong Altered Expression [198]
ETS2 TT9AH0M Strong Altered Expression [199]
EZH2 TT9MZCQ Strong Altered Expression [200]
EZR TTE47YC Strong Genetic Variation [201]
F2RL3 TTD0652 Strong Altered Expression [202]
FAM83B TT1Q347 Strong Biomarker [203]
FBXW7 TT29KY7 Strong Biomarker [204]
FER TTRA9G0 Strong Biomarker [13]
FGF4 TTCEKVZ Strong Biomarker [205]
FGFR3 TTST7KB Strong Biomarker [206]
FHL1 TTI7ENL Strong Posttranslational Modification [207]
FOLR2 TTT54CI Strong Genetic Variation [71]
FOSL1 TTY8LZG Strong Biomarker [208]
FOXM1 TTD3KOX Strong Biomarker [160]
FOXP1 TT0MUCI Strong Biomarker [209]
FUT3 TTUPAD7 Strong Biomarker [210]
GADD45B TTMDW9L Strong Biomarker [211]
GART TTEXB9Z Strong Biomarker [23]
GATA3 TT45KOB Strong Biomarker [27]
GHR TTHJWYD Strong Biomarker [211]
GJB1 TTSJIRP Strong Altered Expression [212]
GJB2 TTRGZX3 Strong Biomarker [213]
GJB6 TTAU8SJ Strong Biomarker [214]
GLIPR1 TTEQF1O Strong Altered Expression [215]
GLRX TTRJCNG Strong Altered Expression [216]
GOT1 TTU507L Strong Altered Expression [217]
GPI TT19JIZ Strong Biomarker [23]
GUSB TTHS7CM Strong Altered Expression [218]
HDAC1 TT6R7JZ Strong Altered Expression [219]
HDGF TTKGV26 Strong Biomarker [220]
HK2 TTK02H8 Strong Biomarker [23]
HLA-A TTHONFT Strong Biomarker [221]
HLA-DQA1 TTU2I3J Strong Genetic Variation [161]
HMGB2 TTA78JQ Strong Biomarker [23]
HOXA11 TTEX4ZA Strong Biomarker [222]
HOXA13 TTN26OM Strong Altered Expression [223]
HOXA5 TTXSVQP Strong Altered Expression [224]
HOXB13 TTZ6I58 Strong Altered Expression [118]
HS6ST2 TTS6LBM Strong Biomarker [225]
HSP90AA1 TT78R5H Strong Biomarker [226]
HSPA8 TTMQL3K Strong Altered Expression [227]
HSPB1 TT9AZWY Strong Altered Expression [228]
HTATIP2 TTC6IX5 Strong Altered Expression [229]
HTRA1 TT8POQR Strong Biomarker [230]
IDO1 TTZJYKH Strong Altered Expression [231]
IFNAR1 TTSYFMA Strong Altered Expression [232]
IGF2R TTPNE41 Strong Biomarker [233]
IGFBP7 TTUQ01B Strong Biomarker [234]
IL11 TTGUYTR Strong Biomarker [235]
IL17F TT2B6PS Strong Altered Expression [236]
IL1R2 TT51DEV Strong Biomarker [237]
IL25 TTVMO5W Strong Biomarker [236]
IL37 TTQTX98 Strong Altered Expression [238]
IL7R TTAWI51 Strong Biomarker [239]
IL9 TT0JTFD Strong Biomarker [240]
IMPDH2 TTTB4UP Strong Biomarker [23]
IRF8 TTHUBNK Strong Biomarker [241]
ITGA11 TTANXZ7 Strong Altered Expression [242]
ITGA6 TT165T3 Strong Altered Expression [243]
ITGA8 TT1FW8B Strong Altered Expression [244]
JAG2 TTOJY1B Strong Biomarker [245]
JAK1 TT6DM01 Strong Biomarker [246]
KAT2B TTVK7SB Strong Biomarker [247]
KCNH1 TT9XKUC Strong Genetic Variation [138]
KCNJ4 TTXF0ZW Strong Biomarker [248]
KCNMA1 TTE87WJ Strong Altered Expression [249]
KDM3A TTKXS4A Strong Biomarker [250]
KDR TTUTJGQ Strong Biomarker [251]
KLK5 TTULSEW Strong Altered Expression [252]
KPNB1 TTHOJ5F Strong Biomarker [253]
KRT17 TTKV0EC Strong Biomarker [254]
KRT19 TT3JF9E Strong Biomarker [255]
LANCL1 TTZW8NS Strong Biomarker [256]
LAPTM4B TTEJQT0 Strong Biomarker [257]
LATS2 TTML7FG Strong Altered Expression [258]
LIFR TTID542 Strong Biomarker [259]
LOXL2 TTFSUHX Strong Altered Expression [260]
LYN TT1RWNJ Strong Altered Expression [261]
MAGEA2 TTOZT28 Strong Biomarker [262]
MALT1 TTCI81G Strong Altered Expression [263]
MAP2K7 TT6QY3J Strong Biomarker [264]
MAP3K2 TTIX0ZU Strong Genetic Variation [265]
MAP4 TT0VFPN Strong Altered Expression [266]
MAPK14 TTQBR95 Strong Altered Expression [46]
MAPK9 TT3IVG2 Strong Biomarker [267]
MDM2 TT9TE0O Strong Altered Expression [268]
MELTF TT8OBT3 Strong Genetic Variation [269]
MGLL TTZ963I Strong Biomarker [270]
MGMT TTJ8DV7 Strong Posttranslational Modification [271]
MLH1 TTISG27 Strong Genetic Variation [272]
MMP11 TTZW4MV Strong Biomarker [273]
MRM2 TTUQ7WN Strong Altered Expression [274]
MS4A1 TTUE541 Strong Biomarker [275]
MSI2 TTTXQF6 Strong Biomarker [276]
MSR1 TT2TDH9 Strong Altered Expression [277]
MTA1 TTO4HUS Strong Biomarker [278]
MUC1 TTBHFYQ Strong Biomarker [279]
MUC16 TTC1PS3 Strong Biomarker [280]
MUTYH TTNB0ZK Strong Biomarker [281]
MYC TTNQ5ZP Strong Altered Expression [282]
MYCBP TTVW4XU Strong Altered Expression [283]
NAPRT TTVR1FW Strong Altered Expression [284]
NDUFA13 TTRU1NG Strong Altered Expression [285]
NEDD8 TTNDC4K Strong Altered Expression [286]
NFE2L2 TTA6ZN2 Strong Genetic Variation [287]
NOTCH3 TTVX7IA Strong Altered Expression [288]
NPM1 TTHBS98 Strong Biomarker [23]
NR1H3 TTECBXN Strong Biomarker [289]
NR3C2 TT26PHO Strong Biomarker [290]
NRP2 TTRXUVC Strong Biomarker [291]
NSD1 TTTSJ3H Strong Genetic Variation [292]
NTSR1 TTTUMEP Strong Altered Expression [293]
OGG1 TTRU01G Strong Biomarker [281]
OLFM4 TTK1CX7 Strong Biomarker [294]
OLR1 TTKSND3 Strong Biomarker [295]
P2RY14 TT72OKI Strong Biomarker [211]
PAM TTF4ZPC Strong Genetic Variation [296]
PAWR TT3I4WV Strong Biomarker [202]
PDCD1LG2 TTW14O3 Strong Altered Expression [297]
PDE4D TTSKMI8 Strong Biomarker [298]
PDK2 TTJGCKM Strong Biomarker [299]
PECAM1 TT4EZB2 Strong Biomarker [300]
PFKFB3 TTTHMQJ Strong Altered Expression [301]
PGRMC1 TTY3LAZ Strong Altered Expression [302]
PHGDH TT8DRCK Strong Altered Expression [303]
PIK3CB TT9H4P3 Strong Biomarker [143]
PKM TT4LOT8 Strong Altered Expression [304]
PLK4 TTGPNZQ Strong Altered Expression [305]
PLOD2 TT8MEUD Strong Biomarker [306]
PPM1D TTENJAB Strong Biomarker [211]
PPP2CA TTHTKNY Strong Biomarker [307]
PPP3CA TTA4LDE Strong Biomarker [29]
PRAME TTPH7T0 Strong Altered Expression [308]
PRDX4 TTPBL9I Strong Altered Expression [309]
PRKCA TTFJ8Q1 Strong Biomarker [310]
PRKD1 TTSLUMT Strong Genetic Variation [311]
PROM1 TTXMZ81 Strong Altered Expression [312]
PRTN3 TT5MLC4 Strong Biomarker [313]
PTK7 TTXH2ZN Strong Altered Expression [314]
PTN TTA9EJK Strong Altered Expression [315]
PTPN13 TT405FP Strong Biomarker [316]
PTPRB TT64I9Q Strong Altered Expression [317]
RAC1 TT2M9CG Strong Biomarker [318]
RCVRN TTDQTEY Strong Biomarker [319]
REG4 TTVZEHU Strong Altered Expression [320]
RHOA TTP2U16 Strong Genetic Variation [28]
RHOB TT6LPFO Strong Biomarker [321]
RICTOR TT143WL Strong Genetic Variation [322]
RIPK4 TTB4S01 Strong Altered Expression [323]
RNF43 TTD91BL Strong Biomarker [324]
ROBO1 TTND1YP Strong Biomarker [325]
ROR1 TTDEJAU Strong Altered Expression [326]
RPS6KA1 TTIXKA4 Strong Altered Expression [327]
RPSA TTLUW5B Strong Altered Expression [328]
RRM1 TTWP0NS Strong Biomarker [23]
RSPO1 TTI9HL4 Strong Altered Expression [329]
RSPO3 TT7HJTF Strong Biomarker [329]
RTN4R TTVRZUO Strong Biomarker [330]
RUNX3 TTKCVO7 Strong Biomarker [331]
S1PR3 TTDYP7I Strong Altered Expression [332]
SATB1 TTLFRIC Strong Biomarker [23]
SDC2 TT5H2F0 Strong Altered Expression [333]
SERPINB3 TT6QLPX Strong Altered Expression [334]
SFTPD TTGLMU7 Strong Genetic Variation [335]
SH2B3 TT36N7Z Strong Genetic Variation [138]
SIK1 TT1H6LC Strong Genetic Variation [336]
SLC12A1 TTS087L Strong Altered Expression [337]
SLC12A3 TTP362L Strong Genetic Variation [338]
SLC12A5 TTH6UZY Strong Altered Expression [339]
SLC15A2 TT27Q3A Strong Biomarker [23]
SLC16A3 TTG6VD5 Strong Altered Expression [340]
SLC19A1 TT09I7D Strong Biomarker [23]
SLC1A5 TTF7WRM Strong Biomarker [341]
SLC3A2 TT5CZSM Strong Biomarker [342]
SLC5A2 TTF8JAT Strong Biomarker [343]
SLC5A7 TTRV7W3 Strong Biomarker [174]
SMAD6 TTON5JB Strong Biomarker [344]
SMARCA4 TTVQEZS Strong Biomarker [345]
SMYD3 TTKLJYX Strong Altered Expression [265]
SOAT2 TTAK0IN Strong Biomarker [346]
SOD2 TT9O4C5 Strong Biomarker [347]
SOX2 TTCNOT6 Strong Biomarker [348]
SOX5 TTXHSZK Strong Biomarker [349]
SP1 TTZEP6S Strong Biomarker [350]
SPDEF TT2ZUPY Strong Altered Expression [94]
SPOCK1 TTF23RE Strong Altered Expression [81]
SPTBN1 TTS9BDA Strong Biomarker [351]
SRC TT6PKBN Strong Biomarker [352]
SRGN TTCHB06 Strong Altered Expression [353]
SRPK1 TTU3WV6 Strong Altered Expression [354]
SRPK2 TTCZEJ9 Strong Biomarker [354]
SRR TTZFUY6 Strong Biomarker [23]
STAT6 TTWOE1T Strong Altered Expression [355]
STC1 TTDLUER Strong Altered Expression [356]
STK33 TTP34DQ Strong Biomarker [357]
STK39 TTYQTIU Strong Biomarker [23]
STMN1 TT7W5OT Strong Altered Expression [358]
SULF2 TTLQTHB Strong Posttranslational Modification [359]
SYK TT2HUPM Strong Altered Expression [360]
TAOK1 TTQY9DH Strong Altered Expression [361]
TBX21 TTNF9PH Strong Biomarker [362]
TF TT8WXAV Strong Biomarker [127]
TFF1 TTNOJIZ Strong Altered Expression [363]
TIAM1 TTNU6I5 Strong Altered Expression [364]
TNFRSF17 TTZ3P4W Strong Altered Expression [365]
TNFSF10 TTA5MS9 Strong Therapeutic [366]
TNFSF13 TTOI1RM Strong Altered Expression [365]
TNKS TTVUSO7 Strong Altered Expression [282]
TNS4 TT1K65C Strong Altered Expression [367]
TOP2A TTCGY2K Strong Biomarker [368]
TOP2B TT4NVEM Strong Altered Expression [368]
TPT1 TT3PTB6 Strong Altered Expression [369]
TRIM28 TTQ2BKV Strong Biomarker [370]
TRIM59 TT613U4 Strong Altered Expression [371]
TRIP10 TTKHTGE Strong Biomarker [372]
TRPA1 TTELV3W Strong Biomarker [373]
TRPC3 TTNVC34 Strong Altered Expression [374]
TSG101 TTHU7JA Strong Altered Expression [375]
TWIST1 TTX1MY7 Strong Altered Expression [376]
UCHL5 TTSX29Z Strong Biomarker [115]
USP10 TT5IH09 Strong Altered Expression [377]
USP8 TT1J07C Strong Altered Expression [378]
UTS2 TTERU0T Strong Biomarker [379]
VDAC1 TTAMKGB Strong Biomarker [380]
VEGFC TT0QUFV Strong Biomarker [381]
VEGFD TTOM5H4 Strong Altered Expression [382]
VSIR TT51SK8 Strong Genetic Variation [383]
WNT7A TT8NARC Strong Biomarker [384]
WRN TT2H5WQ Strong Biomarker [292]
WWP2 TT6TU05 Strong Altered Expression [385]
XRCC5 TTCB9KW Strong Biomarker [386]
YAP1 TT8UN2D Strong Altered Expression [387]
ZEB2 TTT2WK4 Strong Biomarker [388]
ACLY TT0Z6Y2 Definitive Altered Expression [389]
ADAM9 TTTYQNS Definitive Biomarker [390]
AGER TTMO9HF Definitive Biomarker [391]
APEX1 TTHGL48 Definitive Altered Expression [392]
ARG1 TT7ZQEV Definitive Altered Expression [393]
ATAD2 TT9A0HI Definitive Biomarker [394]
BCL2L2 TTQ79W8 Definitive Altered Expression [395]
BSG TT5UJWD Definitive Altered Expression [396]
CD74 TTCMYP9 Definitive Genetic Variation [397]
CD9 TTZEIBV Definitive Biomarker [398]
CDC20 TTBKFDV Definitive Altered Expression [54]
CLDN18 TT6PKBX Definitive Biomarker [399]
CLDN6 TTKSV48 Definitive Altered Expression [400]
CNTN1 TTPR8FK Definitive Biomarker [401]
CRK TTFEUYR Definitive Altered Expression [46]
DCK TTJOCE4 Definitive Biomarker [402]
DGKA TTGL8F0 Definitive Altered Expression [403]
DPYD TTZPS91 Definitive Biomarker [404]
DYRK2 TT84OS6 Definitive Altered Expression [405]
E2F1 TTASI04 Definitive Altered Expression [406]
EP300 TTGH73N Definitive Altered Expression [407]
EREG TTYSB89 Definitive Altered Expression [408]
ERN1 TTKIAT3 Definitive Altered Expression [409]
FASN TT7AOUD Definitive Biomarker [410]
HNF4A TT2F3CD Definitive Biomarker [411]
HNRNPA1 TTPJ9XK Definitive Biomarker [412]
ID1 TTBXVDE Definitive Genetic Variation [413]
IDH1 TTV2A1R Definitive Altered Expression [414]
IL24 TT1EPXZ Definitive Altered Expression [415]
IRF3 TTYR7OH Definitive Altered Expression [416]
LGALS1 TTO3NYT Definitive Altered Expression [417]
MAP3K8 TTGECUM Definitive Biomarker [418]
MMP12 TTXZ0KQ Definitive Biomarker [419]
MUC5AC TTEL90S Definitive Altered Expression [420]
NEDD9 TT1UREA Definitive Biomarker [421]
NLRP1 TTQX29T Definitive Altered Expression [422]
OSM TTIVXSE Definitive Altered Expression [423]
OSMR TTAH0KM Definitive Altered Expression [424]
PARG TT39J16 Definitive Altered Expression [425]
PLK1 TTH4IP0 Definitive Biomarker [426]
PRKCZ TTBSN0L Definitive Biomarker [99]
PRMT5 TTR1D7X Definitive Altered Expression [427]
PTPN11 TT7WUAV Definitive Altered Expression [428]
RECK TTRZBW7 Definitive Altered Expression [429]
S100A9 TT0TMQG Definitive Biomarker [430]
SCGB2A2 TT1W3RE Definitive Altered Expression [431]
SLC34A2 TTQPZTM Definitive Altered Expression [432]
TAGLN2 TTP6BIJ Definitive Biomarker [433]
TK1 TTP3QRF Definitive Biomarker [434]
TP53BP1 TTX4UE9 Definitive Altered Expression [435]
TPX2 TT0PHL4 Definitive Altered Expression [436]
TTK TTP7EGM Definitive Altered Expression [437]
ULK1 TT4D7MJ Definitive Altered Expression [438]
XPA TTGT87E Definitive Genetic Variation [439]
------------------------------------------------------------------------------------
⏷ Show the Full List of 506 DTT(s)
This Disease Is Related to 15 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
SLC25A3 DTCRIWV moderate Altered Expression [440]
ABCC11 DTWN7FC Strong Genetic Variation [441]
SLC11A1 DT650XW Strong Biomarker [442]
SLC12A2 DTHKL3Q Strong Altered Expression [337]
SLC25A16 DTNU9EW Strong Genetic Variation [443]
SLC2A10 DT3BI6S Strong Biomarker [444]
SLC2A3 DT9SQ3L Strong Biomarker [445]
SLC2A5 DTOR02F Strong Altered Expression [446]
SLC4A4 DTWDEIL Strong Biomarker [23]
SLC4A7 DT03V27 Strong Biomarker [23]
SLC5A8 DTE3TAW Strong Posttranslational Modification [447]
ABCA3 DT2T6VQ Definitive Biomarker [448]
SLC35A4 DT2OPRB Definitive Biomarker [449]
SLC44A1 DT3I2SU Definitive Biomarker [450]
SLC52A1 DT7NOKR Definitive Biomarker [451]
------------------------------------------------------------------------------------
⏷ Show the Full List of 15 DTP(s)
This Disease Is Related to 29 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
DIO3 DET89OV moderate Biomarker [66]
UGT2B17 DEAZDL8 moderate Genetic Variation [452]
ACOT13 DEMK5U6 Strong Altered Expression [453]
ACP5 DESITDW Strong Biomarker [454]
ADH1C DEM1HNL Strong Biomarker [455]
AGMAT DEG5L6E Strong Biomarker [456]
AK2 DEY1FJO Strong Altered Expression [457]
AKR1C2 DEOY5ZM Strong Biomarker [458]
ALDH1A1 DE2JP1Y Strong Altered Expression [376]
CYP2A13 DEXZA9U Strong Altered Expression [459]
DDAH1 DEY0TQC Strong Biomarker [460]
FAAH DEUM1EX Strong Altered Expression [461]
FPGS DECWT2V Strong Altered Expression [462]
GMDS DE8K7F3 Strong Altered Expression [463]
HIF1AN DEY1CBW Strong Altered Expression [464]
HK1 DEDMAGE Strong Biomarker [23]
HPRT1 DEVXTP5 Strong Biomarker [465]
HSD17B10 DEGSPC9 Strong Biomarker [127]
MGST1 DEAPJSO Strong Altered Expression [466]
NAT2 DER7TA0 Strong Genetic Variation [467]
PAPSS1 DEDG68B Strong Altered Expression [468]
PARK7 DEPOVCH Strong Biomarker [469]
PMM2 DEBRX3L Strong Biomarker [210]
UBASH3B DE10BJ5 Strong Biomarker [470]
UCK2 DETN1O0 Strong Biomarker [23]
UGT1A3 DEF2WXN Strong Biomarker [471]
GSTM4 DERQ52Z Definitive Altered Expression [472]
LDHC DEQG7F9 Definitive Biomarker [473]
PSAT1 DEBS17P Definitive Biomarker [474]
------------------------------------------------------------------------------------
⏷ Show the Full List of 29 DME(s)
This Disease Is Related to 936 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
ADAM12 OTZKOTDB Limited Biomarker [475]
ADAMTS7 OTVKZ1DV Limited Genetic Variation [10]
AK5 OTTGXLOT Limited Genetic Variation [10]
AKT1S1 OT4JHN4Y Limited Altered Expression [476]
ALKBH3 OTS1CD9Z Limited Biomarker [477]
APOBEC3B OTHLNI51 Limited Biomarker [478]
C1D OTI9PMN1 Limited Genetic Variation [193]
CABLES1 OTMN4XSX Limited Genetic Variation [10]
CISD2 OTVS7S2H Limited Altered Expression [479]
CLDN15 OT9K0KI7 Limited Altered Expression [480]
CLDN5 OTUX60YO Limited Altered Expression [481]
CLPTM1L OTDJWQXI Limited Genetic Variation [482]
COPS6 OTG9AAG0 Limited Biomarker [169]
DCTN4 OTM7C943 Limited Genetic Variation [10]
DOK2 OTIJ38UF Limited Altered Expression [483]
EMX2 OT0V8OYK Limited Altered Expression [484]
ERICH6B OTTQNLM7 Limited Genetic Variation [193]
ERP44 OT7ZI7AG Limited Biomarker [485]
ESRP1 OTNCS4SL Limited Biomarker [486]
ETV5 OTE2OBM4 Limited Altered Expression [487]
FAM227B OTDZYIIY Limited Genetic Variation [10]
FAM83A OTBI16V7 Limited Altered Expression [488]
FRZB OTTO3DPY Limited Biomarker [489]
FUT1 OTODG57A Limited Genetic Variation [490]
GABBR2 OT67RIFY Limited Biomarker [491]
GALK2 OTHR35JF Limited Genetic Variation [10]
GASK1B OT2HPHEI Limited Biomarker [492]
GGPS1 OTVEHG28 Limited Altered Expression [493]
GIPC2 OT68YFO1 Limited Genetic Variation [10]
GPC1 OTQKRSSV Limited Altered Expression [494]
GPR180 OT2P0XNK Limited Biomarker [495]
HAVCR2 OTOL603T Limited Biomarker [496]
HEATR6 OTD3MYS0 Limited Altered Expression [91]
HHLA2 OTYBTVQS Limited Altered Expression [497]
HOXB9 OTMVHQOU Limited Altered Expression [498]
HOXC10 OT5WF17M Limited Biomarker [499]
IGFBP4 OT2HZRBD Limited Posttranslational Modification [500]
KDM4B OT5P1UPY Limited Biomarker [501]
KIF14 OTXHT4JM Limited Altered Expression [502]
KIF23 OTY850JC Limited Biomarker [503]
KIF5B OTT34MT8 Limited Biomarker [504]
KLF17 OT5NWVP7 Limited Biomarker [505]
LAT OTZC1XZ1 Limited Altered Expression [506]
MB OTYWYL2D Limited Altered Expression [507]
MIGA1 OT6BFR2U Limited Genetic Variation [10]
MORF4L1 OTEA6FYJ Limited Genetic Variation [10]
MPZL2 OTKFNDUI Limited Genetic Variation [10]
MUC6 OTPVL723 Limited Altered Expression [508]
NAF1 OTMJKJAK Limited Genetic Variation [10]
NOX1 OTZPJQCC Limited Altered Expression [509]
OLA1 OTAPOTTG Limited Biomarker [510]
PDPN OTBUV19I Limited Biomarker [511]
PKP3 OTPL1HRB Limited Altered Expression [512]
PODXL OTPNQXF3 Limited Altered Expression [513]
PVR OT3N91T7 Limited Biomarker [514]
RAB31 OTMLXQZ0 Limited Genetic Variation [10]
RAB5A OTFR2KM4 Limited Altered Expression [515]
RASSF3 OT4V9SRK Limited Genetic Variation [10]
RBM10 OTES2MES Limited Altered Expression [516]
RGS11 OTIAZ36F Limited Altered Expression [517]
RNLS OTVP2WJM Limited Genetic Variation [193]
RTKN OTSS8XR6 Limited Biomarker [518]
S100A2 OTTGHJ1H Limited Altered Expression [30]
SOS1 OTTCWXC3 Limited Genetic Variation [519]
SPANXA1 OTMK3QIS Limited Biomarker [520]
STXBP6 OTUEKTIP Limited Posttranslational Modification [521]
TEKT5 OTZ5OUHY Limited Genetic Variation [10]
TNKS1BP1 OTBIZECQ Limited Altered Expression [522]
AHNAK OT6KH1WG Disputed Altered Expression [523]
CMTR2 OT82FBWS Disputed Biomarker [29]
EPB41L3 OTS6CHG2 Disputed Altered Expression [524]
FASTK OTTHFZMP Disputed Biomarker [525]
HELLS OTVVV668 Disputed Biomarker [23]
JUNB OTG2JXV5 Disputed Biomarker [526]
KPNA2 OTU7FOE6 Disputed Biomarker [23]
KRT6B OTBXJYHY Disputed Biomarker [37]
NAA10 OTYB9R6I Disputed Biomarker [23]
OPN3 OTON6BFU Disputed Altered Expression [527]
SELENOP OT02B8IR Disputed Biomarker [528]
SIX3 OTP5E3VU Disputed Altered Expression [529]
TMC5 OTO5D86M Disputed Altered Expression [37]
TPI1 OT14KP4B Disputed Biomarker [23]
ACIN1 OTK81F92 moderate Posttranslational Modification [530]
ACTN4 OTCNZAJ5 moderate Altered Expression [531]
ACTR10 OTRF3E58 moderate Altered Expression [532]
ACTR3B OTNEC9UT moderate Altered Expression [532]
ACTR3C OTLAWZPC moderate Altered Expression [532]
AHSA1 OTC7AFHT moderate Altered Expression [46]
ALDH3A1 OTAYZZE6 moderate Biomarker [533]
ARMC8 OTNAXGM7 moderate Biomarker [534]
ASPM OTKXQMNA moderate Biomarker [249]
ATP2C1 OTQN51T3 moderate Biomarker [535]
BCL2L11 OTNQQWFJ moderate Biomarker [536]
BEX4 OT3LXD15 moderate Biomarker [537]
BHLHE41 OTY9GJ1Y moderate Altered Expression [538]
BRMS1 OTV5A6LL moderate Altered Expression [539]
CA11 OT8RX3AJ moderate Altered Expression [97]
CA8 OT9Y8GA8 moderate Altered Expression [97]
CALB2 OTSNMCG9 moderate Biomarker [540]
CBX3 OTOP9RLD moderate Altered Expression [541]
CCL19 OTQ2UJMH moderate Altered Expression [542]
CCL28 OTY6XNQ7 moderate Altered Expression [150]
CDCA2 OTX8UF9J moderate Altered Expression [543]
CDK2AP2 OTR99SJ8 moderate Altered Expression [525]
CENPU OTQ4TZRS moderate Altered Expression [544]
CKAP4 OTDUC9ME moderate Altered Expression [545]
CLDN10 OT2CVAKY moderate Biomarker [546]
CLIC4 OT6KTPKD moderate Genetic Variation [547]
CRABP2 OTY01V9G moderate Biomarker [225]
CTAG1B OTIQGW6U moderate Biomarker [61]
CXCL5 OTZOUPCA moderate Biomarker [548]
DDB1 OTTR2L3Z moderate Biomarker [549]
EEF1A2 OT9Z23K5 moderate Altered Expression [550]
ERVW-1 OTWV8DXJ moderate Altered Expression [551]
FEN1 OT6QGG7O moderate Biomarker [552]
FLOT1 OT0JPPJZ moderate Biomarker [553]
FLOT2 OTZ0QR5L moderate Altered Expression [554]
FMR1NB OT5IC2M2 moderate Biomarker [221]
GATA6 OTO2BC0F moderate Biomarker [555]
GINS2 OT974IYI moderate Altered Expression [556]
GPX2 OTXI2NTI moderate Biomarker [557]
GPX4 OTRAFFX2 moderate Altered Expression [558]
GRAP2 OTS5NIZ3 moderate Altered Expression [46]
GRK6 OT4LZTP9 moderate Biomarker [559]
GRP OT8JDFNI moderate Biomarker [560]
HOXA9 OTKNK5H0 moderate Posttranslational Modification [561]
HOXB3 OT9UC5PE moderate Biomarker [562]
ID3 OTUULW5Z moderate Biomarker [563]
KIF18B OTOBUDOE moderate Altered Expression [564]
KLF15 OTGMQMVR moderate Biomarker [565]
KLF6 OTQY9S7F moderate Biomarker [566]
KLF8 OTUC5CDB moderate Biomarker [567]
LAMTOR2 OTHEDISB moderate Altered Expression [525]
LDHB OT9B1CT3 moderate Altered Expression [568]
LMO3 OTR7AJHN moderate Biomarker [569]
LRP1B OT4YZG2N moderate Genetic Variation [570]
MARCKSL1 OT13J2FM moderate Altered Expression [571]
MCM4 OT19PNNG moderate Biomarker [572]
MED1 OTOO24C4 moderate Biomarker [573]
MFN2 OTPYN8A3 moderate Biomarker [574]
MFSD2A OTVG1VG0 moderate Altered Expression [575]
MRPL28 OT4LUTZU moderate Biomarker [576]
MSN OTZJ4J6G moderate Altered Expression [577]
MUC5B OTPW6K5C moderate Altered Expression [578]
MYBPH OTQJBPUR moderate Altered Expression [579]
MYCL OT1MFQ5U moderate Genetic Variation [580]
MYOD1 OTV2S79X moderate Biomarker [581]
NANOG OTUEY1FM moderate Biomarker [582]
NDUFC2 OT9M119L moderate Biomarker [203]
NNAT OTNRLO7G moderate Altered Expression [583]
NXT1 OT0VO6AY moderate Biomarker [576]
OPCML OT93PQ6Y moderate Biomarker [584]
OPN1LW OTFNUZ7O moderate Biomarker [171]
PAG1 OTFOJUIQ moderate Biomarker [171]
PAQR7 OTIWX5AM moderate Biomarker [352]
PCBP4 OTDLL4NB moderate Biomarker [171]
PCNT OTW4Z65J moderate Biomarker [585]
PIP OTH719AH moderate Biomarker [27]
PLA2G10 OTRZ2L5A moderate Biomarker [98]
PLAGL2 OT6AP4V2 moderate Altered Expression [586]
POLDIP2 OT8SZSJ6 moderate Altered Expression [46]
PRC1 OTHD0XS0 moderate Biomarker [587]
PRPF31 OTSJ0Z1Y moderate Genetic Variation [588]
PSMD2 OT6HZHN7 moderate Biomarker [589]
PTPRG OT9N2WOF moderate Biomarker [590]
PTPRU OTHDO0QG moderate Altered Expression [440]
QKI OTTAUGLB moderate Biomarker [591]
RAD54B OTMWB2P2 moderate Biomarker [552]
RBM47 OT6W67VM moderate Altered Expression [592]
RDX OTNSYUN6 moderate Altered Expression [577]
RELB OTU3QYEF moderate Biomarker [593]
RGMB OT2DROYU moderate Altered Expression [53]
RGN OTD04KB1 moderate Altered Expression [594]
RIT1 OTVNOGOH moderate Genetic Variation [595]
RNF19A OTKWCV80 moderate Altered Expression [46]
RPP14 OT4OYFSK moderate Altered Expression [525]
RPS15A OT0BUA12 moderate Biomarker [596]
SELENBP1 OT3NZNTR moderate Biomarker [597]
SESN2 OT889IXY moderate Altered Expression [328]
SF3B6 OTPRKS6S moderate Altered Expression [525]
SFTPA2 OT6SFOMU moderate Genetic Variation [598]
SIAH2 OTKED2XN moderate Altered Expression [599]
SLIT3 OTU8MKEU moderate Altered Expression [600]
SMARCA1 OT0Y6PTU moderate Altered Expression [601]
SMARCA2 OTSGJ8SV moderate Altered Expression [602]
SNTG1 OT6GBQHI moderate Biomarker [603]
SPAG5 OTCLJ56M moderate Altered Expression [604]
SPINK1 OTSUVAL2 moderate Biomarker [419]
SRF OTW18FQN moderate Biomarker [605]
SRSF1 OTF61HOV moderate Altered Expression [606]
STK11 OT1YZSP3 moderate Biomarker [607]
TAS2R13 OTSTOX5G moderate Altered Expression [608]
TCHP OTVDMHSY moderate Biomarker [609]
TET1 OTZDHT1D moderate Biomarker [610]
TIMM8A OTDX9687 moderate Biomarker [611]
TRIB2 OTHSX3MX moderate Biomarker [612]
TRIB3 OTG5OS7X moderate Altered Expression [608]
TRIM23 OTVIGJ4T moderate Biomarker [613]
ABCE1 OTH19LOA Strong Biomarker [614]
ABCF1 OT6Q079J Strong Genetic Variation [161]
ABHD11 OTJE9UZY Strong Biomarker [615]
ACOT11 OTGPB0SM Strong Biomarker [453]
ACSL4 OTI71MUJ Strong Biomarker [23]
ACTR2 OT3C8U5T Strong Genetic Variation [616]
ADAM28 OT3GBVHL Strong Altered Expression [617]
ADAR OTQNOHR8 Strong Biomarker [618]
ADARB1 OTGKSZEV Strong Altered Expression [619]
ADGRA2 OTBT4W36 Strong Biomarker [620]
ADGRG1 OTQBB8NT Strong Biomarker [621]
ADGRG6 OTY2UBXO Strong Genetic Variation [622]
ADSS1 OTF6FE38 Strong Altered Expression [623]
AFF4 OTTL5Y8R Strong Altered Expression [624]
AGO2 OT4JY32Q Strong Altered Expression [625]
AGRN OTWJENAZ Strong Biomarker [178]
AK1 OT614AR3 Strong Genetic Variation [626]
AK4 OTA0T02Q Strong Biomarker [627]
ALDH18A1 OT6W40XU Strong Biomarker [23]
ALDH1A3 OT1C9NKQ Strong Biomarker [628]
ALDOA OTWRFTIB Strong Biomarker [127]
ALOX15B OTWQQ08W Strong Altered Expression [629]
AMY1A OT6G4B8O Strong Altered Expression [283]
ANLN OTXJY54C Strong Biomarker [630]
ANP32A OTRHPFO2 Strong Biomarker [23]
ANXA6 OT9KIQ0Y Strong Biomarker [470]
APC OTKV0TIK Strong Altered Expression [162]
APOM OTI3FQQC Strong Genetic Variation [161]
APPBP2 OTLNFV4J Strong Biomarker [631]
AQP4 OTA9MYD5 Strong Biomarker [632]
AQP5 OT77GBY8 Strong Altered Expression [633]
ARHGDIA OTEXWJDO Strong Altered Expression [634]
ARHGEF5 OTUVGFT9 Strong Biomarker [635]
ARHGEF7 OT9BPJCL Strong Biomarker [636]
ARID1B OTILK3Q7 Strong Biomarker [637]
ARIH1 OTO3XDR2 Strong Altered Expression [638]
ARL14 OTE4MKOZ Strong Biomarker [639]
ARMH1 OTTJC0D6 Strong Biomarker [256]
ASCL1 OTI4X44G Strong Biomarker [640]
ASF1A OT4S44GP Strong Biomarker [641]
ASXL3 OTNDJWEZ Strong Genetic Variation [103]
ATAD3A OTWF6HBP Strong Biomarker [642]
ATAD3B OTL508AF Strong Biomarker [643]
ATF6 OTAFHAVI Strong Biomarker [409]
ATG16L2 OTJYU0W8 Strong Genetic Variation [644]
ATG3 OT28VBVK Strong Biomarker [645]
ATMIN OTEADE76 Strong Biomarker [646]
ATOH8 OT7SY3BN Strong Altered Expression [344]
ATP5PD OTAJDLE2 Strong Biomarker [127]
ATXN1 OTQF0HNR Strong Biomarker [647]
B4GALT1 OTBCXEK7 Strong Biomarker [648]
BABAM1 OTCFPER6 Strong Genetic Variation [138]
BAG1 OTRQNIA4 Strong Altered Expression [649]
BATF2 OT4XBZC9 Strong Biomarker [650]
BAZ1A OTWHOVZS Strong Genetic Variation [616]
BEX1 OTBQIF0H Strong Altered Expression [537]
BEX5 OTZ2RB6L Strong Biomarker [537]
BIK OTTH1T3D Strong Biomarker [210]
BOK OTDQPDIX Strong Altered Expression [651]
BPIFB1 OTOZYJMO Strong Genetic Variation [269]
BPY2 OT2WQPNQ Strong Biomarker [652]
BRMS1L OTJIW47U Strong Altered Expression [539]
BZW1 OT4GUFIG Strong Altered Expression [653]
BZW2 OTBT0A1B Strong Biomarker [23]
C2 OTHMF4YM Strong Genetic Variation [161]
C5orf34 OTT2ESR4 Strong Altered Expression [654]
CAMK1D OTU24HAU Strong Biomarker [655]
CANX OTYP1F6J Strong Biomarker [327]
CAPG OTJ86KI6 Strong Biomarker [127]
CAPS OTC9GZ2M Strong Altered Expression [656]
CAST OTBXZZGF Strong Genetic Variation [657]
CASTOR1 OTYIH7WK Strong Biomarker [658]
CAVIN2 OTFHHDRU Strong Biomarker [659]
CAVIN3 OTOLBK79 Strong Biomarker [660]
CBLC OT3RKZI9 Strong Biomarker [661]
CCDC6 OTXRQDYG Strong Biomarker [662]
CCDC66 OTE8VSSO Strong Altered Expression [663]
CCDC8 OTO295IH Strong Biomarker [327]
CCL1 OT23NON8 Strong Biomarker [235]
CCL4L2 OTDBSXOU Strong Biomarker [664]
CCRL2 OT5PX0RX Strong Altered Expression [665]
CCT4 OT5D452X Strong Biomarker [666]
CCT5 OTPZ38BT Strong Biomarker [23]
CD151 OTF3UZS7 Strong Altered Expression [667]
CD247 OT45FGUX Strong Altered Expression [668]
CD82 OTH8MC64 Strong Altered Expression [669]
CDCA7 OT12HDZY Strong Biomarker [670]
CDCP1 OTD7RRWK Strong Biomarker [671]
CDH23 OTOJGQ7S Strong Altered Expression [672]
CDK10 OTKP7TTR Strong Altered Expression [673]
CDKN2B OTAG24N1 Strong Genetic Variation [674]
CDKN3 OTBE3H07 Strong Altered Expression [675]
CDX2 OTCG4TSY Strong Genetic Variation [676]
CEACAM21 OTHVCMIP Strong Biomarker [677]
CENPA OT0NEJ4X Strong Altered Expression [54]
CEP55 OTGSG2PA Strong Altered Expression [678]
CEP72 OTVYNPNL Strong Genetic Variation [679]
CFDP1 OTXY7J96 Strong Biomarker [589]
CFHR1 OT72R16T Strong Biomarker [680]
CHD1L OT7CZK7C Strong Altered Expression [681]
CHD4 OTBDEHDP Strong Genetic Variation [269]
CHL1 OT6E6E8P Strong Altered Expression [682]
CHPT1 OT4FJ0K3 Strong Biomarker [218]
CHRNA3 OTCZQY1U Strong Altered Expression [683]
CIDEC OTMDZ56K Strong Biomarker [639]
CKAP2L OT4T73GG Strong Altered Expression [684]
CLDN1 OT27KV99 Strong Genetic Variation [685]
CLDN2 OTRF3D6Y Strong Altered Expression [686]
CLEC10A OTD8HQT6 Strong Biomarker [687]
CLEC14A OT0UJQ4O Strong Posttranslational Modification [688]
CLSTN1 OTQN35G2 Strong Biomarker [689]
COL10A1 OTC4G2YC Strong Altered Expression [94]
COL3A1 OTT1EMLM Strong Biomarker [94]
COL4A5 OTHG60RE Strong Biomarker [444]
COL5A1 OT24078H Strong Biomarker [690]
COPB2 OT82JIGC Strong Altered Expression [691]
COX5A OTP0961M Strong Altered Expression [692]
COX7A1 OTHV25GG Strong Biomarker [692]
CPA3 OTOK8M0V Strong Genetic Variation [693]
CPEB1 OTLCXC6H Strong Biomarker [694]
CPSF3 OTS3KSNG Strong Altered Expression [695]
CRIM1 OTTZNV6Y Strong Altered Expression [259]
CRLS1 OT7XNL0K Strong Altered Expression [696]
CSRP3 OTECBJMV Strong Biomarker [23]
CST1 OTE4I83Q Strong Biomarker [225]
CST6 OTZVHJTF Strong Biomarker [694]
CTBP1 OTVYH2DH Strong Biomarker [348]
CTC1 OTRJY7QD Strong Genetic Variation [697]
CTHRC1 OTV88X2G Strong Altered Expression [698]
CTNNBIP1 OTX9SBJG Strong Biomarker [699]
CTNND1 OTUMPSHR Strong Genetic Variation [700]
CTNND2 OTYKE30Y Strong Biomarker [701]
CTTN OTJRG4ES Strong Altered Expression [702]
CUEDC2 OTWMOLAJ Strong Altered Expression [703]
CUL4B OT2QX4DO Strong Altered Expression [704]
CXCL17 OTRCEVIZ Strong Altered Expression [705]
CYGB OTX153DQ Strong Posttranslational Modification [706]
CYLD OT37FKH0 Strong Biomarker [707]
DAB2 OTRMQTMZ Strong Biomarker [708]
DACH1 OTMKNAGG Strong Altered Expression [344]
DAP OT5YLL7E Strong Posttranslational Modification [709]
DCAF4 OTQU0EUO Strong Altered Expression [182]
DCBLD1 OTA702JK Strong Genetic Variation [616]
DDX53 OTHK3EGZ Strong Biomarker [710]
DDX59 OTHJANS0 Strong Altered Expression [711]
DEDD OTIL349E Strong Biomarker [712]
DGUOK OT78HUZB Strong Biomarker [713]
DHDDS OTVLYBUS Strong Biomarker [218]
DHX15 OT4F98TK Strong Genetic Variation [676]
DHX9 OT5AAOQI Strong Genetic Variation [714]
DIAPH3 OTPOT23F Strong Altered Expression [715]
DIP2A OTXPTR8R Strong Biomarker [652]
DKK4 OTWCCVF6 Strong Biomarker [716]
DLC1 OTP8LMCR Strong Altered Expression [717]
DLD OT378CU9 Strong Biomarker [415]
DMBX1 OT43YF6N Strong Biomarker [718]
DNM1L OTXK1Q1G Strong Biomarker [719]
DOCK4 OTH3XY8B Strong Biomarker [720]
DRG1 OTIFYMI3 Strong Biomarker [721]
DROSHA OTCE68KZ Strong Altered Expression [722]
DUSP4 OT6WAO12 Strong Altered Expression [483]
E2F4 OTB3JFH4 Strong Altered Expression [723]
E2F7 OTWW358N Strong Altered Expression [724]
EAF2 OTSOET5L Strong Biomarker [725]
EBNA1BP2 OTBRVMZH Strong Biomarker [256]
ECRG4 OTHZYUXX Strong Altered Expression [726]
EDAR OT3W2UQS Strong Genetic Variation [441]
EDIL3 OTDVVNS0 Strong Biomarker [727]
EDN3 OTN7Q9BE Strong Biomarker [214]
EFNA1 OTU2NUA2 Strong Altered Expression [191]
EFNB2 OT0DCUOM Strong Altered Expression [244]
EIF2B1 OT4NCVY1 Strong Biomarker [23]
EIF2B4 OTTM5SX1 Strong Biomarker [526]
EIF2B5 OTV3R4RB Strong Biomarker [526]
EIF3E OTI0WG98 Strong Biomarker [23]
EIF3F OTU20K6L Strong Biomarker [728]
EIF4G2 OTEO98CR Strong Biomarker [589]
EIF4H OTGZI072 Strong Biomarker [729]
EIF5 OT79PQUN Strong Biomarker [190]
EIF5AL1 OTLA4ONW Strong Biomarker [190]
ELF3 OTUTLEQO Strong Biomarker [730]
ELK1 OTH9MXD6 Strong Altered Expression [731]
EMD OTR8ZANE Strong Biomarker [732]
EMILIN2 OTOYK5A8 Strong Biomarker [694]
ENKUR OTXXBBQT Strong Biomarker [733]
EPB41L4B OT2K30P7 Strong Altered Expression [734]
ERCC1 OTNPYQHI Strong Biomarker [735]
ERCC2 OT1C8HQ4 Strong Genetic Variation [736]
ERGIC3 OT8RWHN3 Strong Biomarker [737]
ESPL1 OTMGEVOK Strong Biomarker [738]
ESYT2 OTWCXTX3 Strong Altered Expression [739]
ETV4 OT8C98UZ Strong Altered Expression [276]
EYA4 OTINGR3Z Strong Posttranslational Modification [740]
FA2H OT8HA13U Strong Altered Expression [741]
FAIM2 OT6QINVO Strong Biomarker [742]
FAM111B OT9IQ9NV Strong Biomarker [743]
FAM13A OTZ6GN0Q Strong Genetic Variation [744]
FANCC OTTIDM3P Strong Genetic Variation [145]
FBL OTRODIE5 Strong Biomarker [23]
FBLN2 OTEHR7N7 Strong Biomarker [745]
FBXL7 OTNUK1DJ Strong Biomarker [746]
FBXO22 OTEJ5MO0 Strong Altered Expression [747]
FBXW11 OT2A6RLR Strong Genetic Variation [748]
FERMT1 OT626PBA Strong Altered Expression [749]
FERMT2 OTZNPWWX Strong Biomarker [750]
FGA OTMIHY80 Strong Biomarker [751]
FGF22 OTVIX6J0 Strong Biomarker [752]
FGF9 OT2SKDGM Strong Altered Expression [753]
FGL1 OTT0QHQ1 Strong Genetic Variation [754]
FKBP11 OTY2GC67 Strong Biomarker [23]
FNDC3B OTBILGDR Strong Biomarker [755]
FOXA2 OTJOCVOY Strong Altered Expression [756]
FOXD3 OTXYV6GO Strong Altered Expression [757]
FOXP4 OTHCGIEZ Strong Genetic Variation [758]
FRY OT74IAG2 Strong Genetic Variation [138]
FSTL1 OT6KEZUD Strong Altered Expression [759]
FUT2 OTLXM6WI Strong Biomarker [760]
GABBR1 OTU5A52J Strong Genetic Variation [161]
GABPA OT9YB2SA Strong Genetic Variation [761]
GALNT14 OT9BSDDQ Strong Altered Expression [762]
GALNT6 OTOQQVH1 Strong Biomarker [763]
GAR1 OTA580RX Strong Biomarker [23]
GBE1 OTK2N05B Strong Biomarker [764]
GBP1 OTUM7RPJ Strong Biomarker [15]
GBX2 OTW0ZI4D Strong Altered Expression [765]
GCC2 OTT5I9FM Strong Biomarker [766]
GEMIN4 OTX7402E Strong Biomarker [589]
GGA2 OT43HO27 Strong Biomarker [767]
GINS4 OTCVOO3S Strong Altered Expression [768]
GK5 OT65U8L1 Strong Altered Expression [769]
GKN1 OT7ZYFQ9 Strong Biomarker [770]
GKN2 OTR9DOYG Strong Biomarker [103]
GNG11 OTHIXBGW Strong Biomarker [526]
GNPNAT1 OTOYH4L9 Strong Biomarker [23]
GOPC OTRBGH71 Strong Biomarker [771]
GORASP2 OTL3PLD2 Strong Biomarker [772]
GPC5 OT8NR7GC Strong Altered Expression [773]
GPHN OTAKK1SV Strong Biomarker [774]
GPR158 OTYOC1RQ Strong Biomarker [775]
GPRC5A OTPOCWR7 Strong Biomarker [776]
GRWD1 OT6M13ZV Strong Biomarker [23]
GUK1 OTLI0HRU Strong Biomarker [777]
H1-10 OTBWDA4E Strong Biomarker [23]
HBE1 OTJPKMX4 Strong Biomarker [778]
HCP5 OTV0YRI8 Strong Altered Expression [779]
HES7 OT6F9R7P Strong Altered Expression [763]
HIP1 OT7AKCFQ Strong Altered Expression [780]
HLA-DQA2 OT1DH0N9 Strong Genetic Variation [161]
HMGB3 OTCJ2EZY Strong Biomarker [94]
HMMR OT4M0JTZ Strong Biomarker [178]
HNF1B OTSYIC3T Strong Genetic Variation [138]
HNRNPD OT5UO1FA Strong Biomarker [781]
HNRNPK OTNPRM8U Strong Biomarker [782]
HOPX OTBSR6C9 Strong Biomarker [783]
HORMAD1 OT7DR5T2 Strong Altered Expression [784]
HOXA10 OTB6GQ09 Strong Biomarker [785]
HOXA3 OTIX5XFB Strong Altered Expression [786]
HOXB2 OTTD6HMV Strong Biomarker [787]
HOXB4 OTH1HRW5 Strong Biomarker [562]
HOXB7 OTC7WYU8 Strong Altered Expression [788]
HOXC13 OT52AVNA Strong Altered Expression [789]
HUWE1 OTFH6BJS Strong Altered Expression [790]
HYKK OTBK1QPN Strong Biomarker [791]
ID4 OTPMJ39I Strong Altered Expression [792]
IDH3A OT5QQB5L Strong Biomarker [793]
IFIT2 OTI4EOAR Strong Altered Expression [794]
IFITM1 OTECO1G8 Strong Altered Expression [795]
IFITM3 OT2QP8D3 Strong Biomarker [796]
IGBP1 OTTHH4YE Strong Altered Expression [307]
IGF2BP1 OT9G360P Strong Biomarker [797]
IGF2BP3 OTB97VIK Strong Altered Expression [798]
IL17B OTS86H50 Strong Altered Expression [236]
IL17C OTKXIVNQ Strong Altered Expression [236]
IL1F10 OTJAASGC Strong Biomarker [799]
IMMT OTBDSLE7 Strong Altered Expression [800]
INF2 OT8ZM13C Strong Genetic Variation [623]
INSL4 OTK9F0LX Strong Altered Expression [801]
INSYN2B OTJGTKK4 Strong Altered Expression [802]
IPO4 OT2N5020 Strong Biomarker [23]
IPO5 OTAK40ED Strong Biomarker [23]
IQSEC1 OTK1PBFD Strong Altered Expression [803]
IREB2 OT747D24 Strong Altered Expression [791]
IRF4 OT1DHQ1P Strong Altered Expression [804]
IRX5 OT05J514 Strong Altered Expression [805]
ISYNA1 OT49ONSE Strong Biomarker [806]
ITIH5 OTP46PZM Strong Altered Expression [807]
ITPKA OTX5ERUD Strong Altered Expression [808]
ITPRIPL1 OTJ5H965 Strong Biomarker [103]
JMJD6 OTILR7E4 Strong Biomarker [809]
KCNK15 OT8ELIFL Strong Biomarker [775]
KHDRBS2 OTEKL45T Strong Genetic Variation [292]
KIAA1217 OTRMK3PU Strong Biomarker [810]
KIDINS220 OTLBH2MA Strong Genetic Variation [811]
KIF13A OTSSZGBQ Strong Biomarker [812]
KIF16B OTDWIFQ2 Strong Biomarker [813]
KIF18A OTSMBJ24 Strong Altered Expression [814]
KIF20A OTXOQHE0 Strong Biomarker [815]
KIF2A OT2WQ6QD Strong Biomarker [816]
KIF2C OTJ8G3NP Strong Altered Expression [817]
KLF10 OT4F4UGS Strong Altered Expression [818]
KRT16 OTGA0EQN Strong Altered Expression [113]
KRT5 OTVGI9HT Strong Biomarker [37]
KRT8 OTTM4X11 Strong Altered Expression [819]
KRTAP8-1 OTKXKZ40 Strong Biomarker [820]
LAD1 OT6YGTVX Strong Biomarker [415]
LAMA3 OTFME7HT Strong Biomarker [821]
LAYN OT9A9Q1X Strong Biomarker [694]
LDB2 OT6Y8IEK Strong Genetic Variation [161]
LDOC1 OTWZH4O9 Strong Biomarker [822]
LGALS4 OTKQCG0H Strong Altered Expression [823]
LGR6 OTPZ1PWR Strong Biomarker [824]
LHX3 OTQ5BAJ9 Strong Biomarker [825]
LIN28B OTVWP0FN Strong Biomarker [826]
LMNB1 OT100T3P Strong Biomarker [23]
LMNB2 OTXRDUOS Strong Altered Expression [827]
LOXL1 OTA0NEJU Strong Altered Expression [242]
LPCAT1 OTCV7AGV Strong Biomarker [828]
LPIN1 OTQ75KF2 Strong Biomarker [829]
LPP OT6TU8SE Strong Genetic Variation [830]
LRP12 OTRT1UJ7 Strong Posttranslational Modification [831]
LRPPRC OTXSK5LP Strong Biomarker [832]
LXN OTZQ2M6Y Strong Altered Expression [833]
LYNX1 OTK4103B Strong Biomarker [834]
LYPD5 OTGP7UKA Strong Biomarker [278]
MAD2L1 OTXNGZCG Strong Biomarker [835]
MAFG OTBQFUZH Strong Biomarker [836]
MAP1LC3A OTPMGIU4 Strong Biomarker [837]
MAP2K4 OTZPZX11 Strong Biomarker [838]
MAPK4 OTVWWUYS Strong Altered Expression [839]
MARCHF9 OTWF84QT Strong Biomarker [840]
MARVELD3 OTFTPOJ4 Strong Biomarker [694]
MBD2 OTUQPP0R Strong Altered Expression [610]
MCAT OTH07FIW Strong Biomarker [168]
MCM10 OTV0O3JN Strong Biomarker [572]
MCM2 OTGGORIQ Strong Biomarker [572]
MCM5 OTAHLB62 Strong Biomarker [605]
MCM8 OTC93H3S Strong Biomarker [605]
MCTS1 OT7SAOJP Strong Biomarker [168]
MED19 OTT9RT5N Strong Biomarker [841]
MEST OT8Q4U8Y Strong Biomarker [842]
METTL3 OTSXP1M3 Strong Altered Expression [843]
MFF OTEVIXOM Strong Genetic Variation [844]
MID1 OTWN1PGU Strong Altered Expression [845]
MIIP OT79EXZ7 Strong Altered Expression [846]
MINDY4 OTBZ2SZB Strong Altered Expression [633]
MIP OTEBLU3E Strong Biomarker [847]
MOCS2 OTSPV7AX Strong Genetic Variation [292]
MORF4L2 OT8OI3EC Strong Altered Expression [249]
MPC1 OT6DYFUO Strong Biomarker [848]
MPZL3 OTC4LRBU Strong Genetic Variation [616]
MRE11 OTGU8TZM Strong Biomarker [23]
MRPL12 OTU41AM0 Strong Biomarker [23]
MRPL41 OTG5URO4 Strong Biomarker [849]
MRPS5 OTZZR208 Strong Biomarker [23]
MRTFB OT9OXGS9 Strong Biomarker [850]
MSH3 OTD3YPVL Strong Biomarker [851]
MSH5 OTDARQT3 Strong Genetic Variation [161]
MSH6 OT46FP09 Strong Biomarker [851]
MT1G OTAV1OCR Strong Biomarker [621]
MTBP OTWLCW9C Strong Biomarker [852]
MTERF1 OT3EIK39 Strong Altered Expression [853]
MTO1 OT7HCZ1D Strong Biomarker [591]
MTSS1 OT5DTDO2 Strong Altered Expression [854]
MTX1 OTLSDNZO Strong Genetic Variation [138]
MUC21 OTQ8GP5L Strong Altered Expression [855]
MUC4 OTLT11V1 Strong Altered Expression [167]
MUCL3 OTGAD3I0 Strong Genetic Variation [161]
MVP OTJGHJRB Strong Altered Expression [856]
MYBL2 OTZ3JX8Q Strong Biomarker [857]
MYH14 OT1TZEJK Strong Genetic Variation [739]
NAPSA OT6F8IAL Strong Biomarker [858]
NCAPG OT1AI9EO Strong Biomarker [859]
NCAPG2 OTZYENKO Strong Biomarker [860]
NCBP1 OTYBR927 Strong Biomarker [704]
NCOR1 OT04XNOU Strong Genetic Variation [861]
NCOR2 OTY917X0 Strong Altered Expression [541]
ND5 OT45LW1K Strong Altered Expression [862]
ND6 OTG47B7B Strong Biomarker [863]
NECTIN3 OTS8N7MK Strong Biomarker [864]
NEK10 OTN0JAYL Strong Genetic Variation [138]
NELL2 OTS4MJZ7 Strong Biomarker [291]
NEUROD1 OTZQ7QJ2 Strong Genetic Variation [865]
NFATC2 OTK5T6HZ Strong Biomarker [866]
NFIL3 OTQH9HM3 Strong Altered Expression [867]
NFIX OT1DPZAE Strong Altered Expression [868]
NFS1 OT0HUS40 Strong Biomarker [869]
NMU OTW9X7BQ Strong Altered Expression [94]
NOLC1 OTKDZU0D Strong Biomarker [130]
NOP56 OTT67SRZ Strong Biomarker [23]
NOP58 OTP536HD Strong Biomarker [23]
NPM3 OTIAM1A3 Strong Biomarker [23]
NR2F6 OTNVO2B6 Strong Biomarker [870]
NSUN3 OTLBKU22 Strong Genetic Variation [292]
NUDT1 OTZSES3W Strong Genetic Variation [269]
NUDT21 OTZHKWAR Strong Biomarker [23]
NUP210 OT3BLQ9M Strong Altered Expression [871]
NUP58 OTMLLWJW Strong Biomarker [872]
OCA2 OTDWIGBF Strong Altered Expression [873]
OCIAD2 OTSWB4SZ Strong Altered Expression [874]
OCLN OTSUTVWL Strong Biomarker [875]
OIP5 OTI5C2DE Strong Biomarker [859]
ORAI3 OTUP3OH3 Strong Biomarker [876]
ORM1 OTZKSBRE Strong Biomarker [877]
OSR1 OTB19LEQ Strong Biomarker [562]
OTUD3 OTHUWQHP Strong Genetic Variation [878]
OTUD7B OTMVM8R7 Strong Biomarker [879]
OTX2 OTTV05B1 Strong Altered Expression [718]
OVOL2 OTFM1GKF Strong Altered Expression [880]
PABPC4 OTICKKBQ Strong Biomarker [23]
PACC1 OTKBS8CC Strong Genetic Variation [881]
PAFAH1B1 OT9T2TCJ Strong Altered Expression [882]
PAIP1 OTL2F5T5 Strong Altered Expression [883]
PCBD1 OTDSRUD5 Strong Biomarker [23]
PCDH7 OTP091X8 Strong Altered Expression [884]
PCDHGB6 OT1Y20JS Strong Biomarker [885]
PCNP OTJUQ122 Strong Biomarker [886]
PDCD5 OT6T2DDL Strong Altered Expression [887]
PDK4 OTCMHMBZ Strong Biomarker [888]
PDZK1IP1 OTWA6M5K Strong Biomarker [889]
PEBP4 OTKDCVC6 Strong Altered Expression [890]
PELI1 OTMLBCLC Strong Altered Expression [891]
PERP OTP0YL53 Strong Biomarker [892]
PFN1 OTHTGA1H Strong Altered Expression [893]
PHF5A OTS94JFM Strong Biomarker [894]
PHLDA2 OTMV9DPP Strong Biomarker [895]
PHLPP1 OTIFXW8D Strong Altered Expression [896]
PHLPP2 OTXB1OUI Strong Altered Expression [896]
PIAS1 OTZVAHZI Strong Biomarker [897]
PIGN OTHHTJKX Strong Biomarker [23]
PIK3R3 OTXGJ8N1 Strong Biomarker [898]
PINK1 OT50NR57 Strong Biomarker [899]
PITX1 OTA0UN4C Strong Altered Expression [900]
PITX2 OTWMXAOY Strong Altered Expression [901]
PIWIL1 OT7CRGZ3 Strong Biomarker [902]
PKD2 OTIXBU8H Strong Biomarker [903]
PKNOX1 OTUDMNHX Strong Altered Expression [904]
PLEC OTU4XDEG Strong Biomarker [905]
PLEK2 OTUBWUUK Strong Altered Expression [906]
PLIN2 OTRXJ9UN Strong Genetic Variation [907]
PLPP4 OTH5EXZC Strong Biomarker [908]
PMEPA1 OTY8Z9UF Strong Altered Expression [909]
POLE2 OTAC9V6L Strong Altered Expression [910]
POLQ OTBHK0E6 Strong Altered Expression [305]
POLR1D OTOCZQNA Strong Biomarker [23]
POU2AF1 OTOO6WHL Strong Biomarker [346]
POU2F2 OTPV0J0C Strong Biomarker [370]
POU3F2 OT30NFOC Strong Altered Expression [911]
PPAN OT0UFQBZ Strong Biomarker [23]
PPP1R17 OT19635T Strong Biomarker [214]
PPP1R18 OT0JVGOZ Strong Genetic Variation [161]
PPP1R8 OTH5KB2P Strong Altered Expression [464]
PPP2R1A OTYA3GB4 Strong Genetic Variation [28]
PRDM1 OTQLSVBS Strong Altered Expression [912]
PRDM16 OT0BGA27 Strong Altered Expression [913]
PRDM2 OT8L7CGX Strong Genetic Variation [914]
PRDX1 OTZ3BEC4 Strong Altered Expression [915]
PRDX3 OTLB2WEU Strong Altered Expression [916]
PRPF19 OTQ1STV3 Strong Altered Expression [917]
PRSS3 OTN3S5YB Strong Biomarker [252]
PSD OTUZIXUZ Strong Biomarker [918]
PSMA7 OTPHI6ST Strong Biomarker [919]
PSMD7 OT7PZZ4K Strong Biomarker [256]
PTGES3 OTPPQWI0 Strong Altered Expression [158]
PTPA OTRGFOI7 Strong Biomarker [920]
PTPRH OTDUHQGF Strong Posttranslational Modification [921]
PTPRT OTV5TXNN Strong Genetic Variation [922]
PTRH2 OTBU39Q1 Strong Biomarker [923]
PXN OTVMMUOF Strong Altered Expression [924]
PYCR1 OTQHB52T Strong Altered Expression [750]
RAB27B OTPF9D0K Strong Biomarker [925]
RAB3GAP1 OT4DQ8F2 Strong Biomarker [130]
RABEPK OTCZSREH Strong Biomarker [256]
RABGEF1 OTWC3Z3R Strong Biomarker [926]
RAD51B OTCJVRMY Strong Genetic Variation [138]
RAD52 OT0OTDHI Strong Genetic Variation [269]
RALY OT78NNWY Strong Genetic Variation [138]
RANGRF OTKQC813 Strong Biomarker [23]
RAP1A OT5RH6TI Strong Biomarker [926]
RASGRF1 OTNWJ7EN Strong Genetic Variation [519]
RASSF1 OTEZIPB7 Strong Posttranslational Modification [271]
RBBP8 OTRHJ3GI Strong Altered Expression [663]
RBL2 OTBQSOE6 Strong Biomarker [130]
RBM3 OTAJ7R31 Strong Altered Expression [927]
RBMY1A1 OTM2F25H Strong Genetic Variation [928]
RCC2 OTUJVTLS Strong Biomarker [929]
RCCD1 OT60N06L Strong Altered Expression [930]
RCL1 OT7O00YX Strong Biomarker [23]
RDM1 OTBSJEAG Strong Biomarker [931]
REG1B OTSC2133 Strong Biomarker [932]
RETN OTW5Z1NH Strong Biomarker [933]
REXO2 OTLKKURG Strong Biomarker [210]
RFC3 OT1MS7AO Strong Biomarker [934]
RFC4 OTWALD2R Strong Altered Expression [935]
RGS17 OT5RVUDS Strong Altered Expression [936]
RHOJ OTWI65OA Strong Biomarker [937]
RMC1 OT7K8MTJ Strong Biomarker [938]
RMDN1 OTE1NB6U Strong Genetic Variation [939]
RMDN2 OTK5WSFI Strong Genetic Variation [939]
RMDN3 OTKO7AUM Strong Genetic Variation [939]
RNF39 OTUQA9JT Strong Genetic Variation [161]
RPL10A OTDLCJ53 Strong Biomarker [23]
RPL13A OTME3VXN Strong Biomarker [23]
RPL17 OTTYMPS6 Strong Biomarker [940]
RPL27A OTQQHPL0 Strong Biomarker [23]
RPL36A OT1LYV85 Strong Biomarker [941]
RPS6 OTT4D1LN Strong Altered Expression [942]
RRAD OTW2O4GD Strong Posttranslational Modification [943]
RRAS OTBBF28C Strong Altered Expression [158]
RREB1 OT62460U Strong Biomarker [792]
RRS1 OTTNCZN6 Strong Biomarker [23]
RSPO2 OT3HHXU0 Strong Altered Expression [329]
RUFY3 OTMA4YA4 Strong Altered Expression [944]
RUVBL1 OTWV19L7 Strong Altered Expression [945]
S100A11 OTI57KDN Strong Altered Expression [946]
S100A7 OTJFVJRF Strong Biomarker [947]
S100A7A OTNM8DCP Strong Biomarker [948]
S100P OTJCXNJG Strong Genetic Variation [949]
SAMHD1 OTBCIBC7 Strong Posttranslational Modification [950]
SASS6 OT1V8H40 Strong Altered Expression [951]
SCGB3A2 OTB63PHR Strong Altered Expression [952]
SDCBP OTS3NCC5 Strong Altered Expression [953]
SEC31A OT2U42AC Strong Biomarker [954]
SEMA4B OT1Y3YZD Strong Biomarker [62]
SEMA5A OTUOIOJV Strong Altered Expression [955]
SEMA7A OT0ZJK64 Strong Biomarker [956]
SERPINB2 OT72QLZB Strong Altered Expression [957]
SET OTGYYQJO Strong Biomarker [958]
SETX OTG3JNOQ Strong Biomarker [959]
SFN OTLJCZ1U Strong Biomarker [960]
SFRP1 OT0U9G41 Strong Biomarker [961]
SFTA2 OTVRIUIV Strong Biomarker [37]
SFTPA1 OT87XL1U Strong Altered Expression [962]
SFTPB OTOHS07E Strong Biomarker [963]
SFXN1 OTL66767 Strong Biomarker [23]
SGTA OTKOJ3JB Strong Biomarker [964]
SH2B1 OTJZO2CI Strong Altered Expression [82]
SH3BGRL3 OTKMW34I Strong Altered Expression [76]
SH3BP4 OTVIRKW7 Strong Biomarker [965]
SH3PXD2A OTYRQJIH Strong Biomarker [966]
SH3RF1 OT7MYGYO Strong Genetic Variation [967]
SHISA3 OTE8TPCP Strong Altered Expression [968]
SHMT1 OTIINA3J Strong Biomarker [969]
SIM1 OTYKFPKZ Strong Biomarker [562]
SIPA1L3 OTNYFUM3 Strong Posttranslational Modification [970]
SIVA1 OTDT0XZK Strong Genetic Variation [623]
SIX2 OTYOVGSC Strong Biomarker [971]
SIX4 OTG2HFH0 Strong Biomarker [971]
SIX6 OTD1RD9D Strong Biomarker [971]
SKI OT4KJ8F6 Strong Biomarker [972]
SKP1 OT5BPAZ4 Strong Biomarker [960]
SLC16A4 OT1YXBKC Strong Altered Expression [340]
SLN OTERIU75 Strong Biomarker [973]
SLURP1 OT89YD2E Strong Genetic Variation [974]
SMAD2 OTC6VB4K Strong Altered Expression [268]
SMAD4 OTWQWCKG Strong Genetic Variation [975]
SMAD5 OTQNSVCQ Strong Genetic Variation [976]
SMARCC1 OTUOMBE7 Strong Biomarker [23]
SMARCD1 OTHFFT6G Strong Altered Expression [977]
SMUG1 OT2YIOCQ Strong Biomarker [978]
SND1 OTT734JN Strong Biomarker [979]
SNRPG OTWX4XK1 Strong Biomarker [23]
SOCS2 OTBPNKJQ Strong Biomarker [980]
SOX18 OTPUMHWA Strong Altered Expression [981]
SOX21 OTNT50CC Strong Biomarker [982]
SOX30 OTGT38E3 Strong Biomarker [983]
SOX6 OTT0W0LE Strong Biomarker [984]
SOX7 OTOZOFAG Strong Altered Expression [985]
SPANXC OT1033B9 Strong Altered Expression [101]
SPATA2 OTOA45GL Strong Biomarker [940]
SPC25 OTCAS0OH Strong Altered Expression [986]
SPOP OTP0107S Strong Biomarker [987]
SPRR1B OTXNW3P6 Strong Altered Expression [988]
SPRY4 OT2VK9N0 Strong Biomarker [775]
SRCIN1 OTQZNQQ5 Strong Biomarker [989]
SRM OT4N5MDP Strong Biomarker [23]
SRSF2 OTVDHO6U Strong Altered Expression [354]
ST18 OTPRIMTA Strong Genetic Variation [292]
STAT2 OTO9G2RZ Strong Altered Expression [355]
STIP1 OT7TXLOX Strong Biomarker [990]
STK19 OTYM6437 Strong Genetic Variation [161]
STK24 OTGUHOIL Strong Altered Expression [991]
STPG4 OT5K4UFL Strong Biomarker [217]
STRBP OTU7XLZL Strong Biomarker [23]
SUCLG2 OT0KHLY2 Strong Biomarker [23]
SUMO1 OTJFD4P5 Strong Altered Expression [992]
SUN1 OTIU8V4U Strong Biomarker [993]
SUPT7L OTZJCPN1 Strong Altered Expression [994]
SUV39H2 OTU0F4LL Strong Biomarker [995]
SYBU OT3FQV7N Strong Genetic Variation [939]
SYNGR2 OTJX84RI Strong Genetic Variation [120]
SYT13 OTG94RJ4 Strong Biomarker [996]
TAF8 OTWWGCHV Strong Biomarker [958]
TAOK2 OTNUMOZ1 Strong Biomarker [361]
TBX5 OT70PISV Strong Genetic Variation [748]
TCF19 OT7NKLF9 Strong Altered Expression [997]
TCF21 OT393IMA Strong Altered Expression [998]
TDRD9 OTS4UBI8 Strong Altered Expression [999]
TEAD4 OTJS0T2B Strong Biomarker [1000]
TENM1 OTSKSU4V Strong Genetic Variation [1001]
TERF2IP OT3M5P3G Strong Biomarker [926]
TESC OTI8C76M Strong Genetic Variation [338]
TFAM OTXXV5V7 Strong Altered Expression [1002]
TFAP2B OTR1T8E9 Strong Altered Expression [1003]
TFAP2C OTUDIW05 Strong Biomarker [1004]
TFDP1 OT6RZ7VT Strong Altered Expression [781]
TFDP2 OTKQFX5H Strong Biomarker [1005]
TFF3 OTJJDRTU Strong Biomarker [1006]
THAP7 OTZDVYC8 Strong Altered Expression [1007]
THBS2 OTXET551 Strong Altered Expression [1008]
TIGAR OTR7NMRJ Strong Biomarker [1009]
TIMM10 OT99QR7R Strong Biomarker [23]
TJP1 OTBDCUPK Strong Genetic Variation [976]
TLE1 OT50MRZ1 Strong Biomarker [1010]
TM4SF4 OTRI8EHN Strong Biomarker [1011]
TMED10 OTUXSHH7 Strong Altered Expression [158]
TMEM106B OTUWA6NW Strong Genetic Variation [1012]
TNFRSF6B OTKAN9G7 Strong Altered Expression [1013]
TNMD OTHLVA9G Strong Biomarker [707]
TNXB OTVBWAV5 Strong Genetic Variation [161]
TOMM40 OTZDQ29F Strong Biomarker [23]
TOP3A OT3CKUI9 Strong Biomarker [368]
TOX3 OTC9NR4W Strong Biomarker [496]
TP53I3 OTSCM68G Strong Biomarker [849]
TRAF3IP3 OTNG0L8X Strong Genetic Variation [1014]
TRAF4 OTJLRVMC Strong Altered Expression [1015]
TRAT1 OTMPUNPD Strong Biomarker [1016]
TRIM11 OTMD6IM2 Strong Biomarker [1017]
TRIM15 OTNYAKP6 Strong Altered Expression [1018]
TRIM25 OT35SG1R Strong Altered Expression [1019]
TRIM31 OT7VW6RP Strong Genetic Variation [161]
TRIM58 OT7OIIRH Strong Posttranslational Modification [1020]
TRIP13 OTFM3TI9 Strong Biomarker [1021]
TROAP OTC8CE0R Strong Biomarker [1022]
TSBP1 OT5GE8IO Strong Genetic Variation [161]
TSPY1 OTPY57X4 Strong Biomarker [194]
TTC21A OTBJ9JKF Strong Biomarker [1023]
TTF1 OT4K90WD Strong Altered Expression [858]
TTN OT0LZ058 Strong Biomarker [1024]
ACAT2 OTZ092ZJ Definitive Biomarker [1025]
ANAPC11 OTK2SJXR Definitive Altered Expression [1026]
ARHGAP35 OTJ8POG0 Definitive Biomarker [1027]
ATP5F1D OTXTAG2V Definitive Altered Expression [472]
BCL7B OT8DQQRD Definitive Biomarker [1028]
BHLHE40 OTITX14U Definitive Biomarker [1029]
BPTF OTD1RZAD Definitive Biomarker [1030]
BTG3 OT9ANHVT Definitive Altered Expression [1031]
BTNL2 OTTTEMZA Definitive Genetic Variation [1032]
C18orf54 OT4WJKTF Definitive Genetic Variation [1033]
CALU OTSYQN71 Definitive Biomarker [1034]
CAPN8 OTXTW2I4 Definitive Biomarker [1035]
CASP14 OTKY93H9 Definitive Altered Expression [1036]
CCAR2 OTLUDG5T Definitive Genetic Variation [1037]
CCNL2 OT0NIKYM Definitive Biomarker [1038]
CEACAM7 OTKFDTZY Definitive Biomarker [55]
CIB1 OT4BVCRU Definitive Biomarker [477]
CIP2A OTVS2GXA Definitive Biomarker [1039]
CLCA2 OTF191LZ Definitive Biomarker [1040]
CLDN3 OT71MN9S Definitive Genetic Variation [949]
CLDN7 OTNE0XHQ Definitive Biomarker [685]
CPSF4 OT53UK5L Definitive Altered Expression [1041]
CRISP2 OT8HLTV5 Definitive Altered Expression [1042]
CRKL OTOYSD1R Definitive Biomarker [1043]
CRYGD OTW29JC4 Definitive Altered Expression [1044]
CXCL14 OTM189TA Definitive Altered Expression [1045]
DNAJB4 OTUD01BK Definitive Genetic Variation [10]
DUSP6 OT4H6RKW Definitive Posttranslational Modification [1046]
ECT2 OTQDUCT6 Definitive Altered Expression [1047]
EIF3A OTFABY9G Definitive Biomarker [1034]
ENO1 OTB1KWJS Definitive Biomarker [1048]
ENO2 OTRODL0T Definitive Altered Expression [1048]
ERP29 OTNKANMH Definitive Biomarker [1049]
ERRFI1 OT7VZ2IZ Definitive Biomarker [941]
FOXA1 OTEBY0TD Definitive Altered Expression [1050]
FOXO3 OTHXQG4P Definitive Altered Expression [1051]
GALNT3 OT7M67WT Definitive Altered Expression [1052]
GATA1 OTX1R7O1 Definitive Altered Expression [416]
GNAS OTMH8BKJ Definitive Genetic Variation [1053]
GOLM1 OTOZSV6O Definitive Biomarker [1054]
GORASP1 OTQS91S7 Definitive Biomarker [1055]
HIC1 OTI9TWY4 Definitive Genetic Variation [1037]
HOXA4 OTNVTQDT Definitive Altered Expression [888]
HSPA14 OTZCA5LK Definitive Altered Expression [1056]
ING4 OT0VVG4V Definitive Biomarker [1057]
IQGAP1 OTZRWTGA Definitive Biomarker [1058]
KIF15 OTJRJEXL Definitive Biomarker [1059]
KIF4A OT3UWL7D Definitive Biomarker [1060]
KLF5 OT1ABI9N Definitive Biomarker [1061]
LAMA1 OTQZMP86 Definitive Altered Expression [1062]
LAMA2 OTFROQWE Definitive Altered Expression [1062]
LAMP3 OTN0XL3W Definitive Posttranslational Modification [1063]
LIMD1 OTN1CG6R Definitive Genetic Variation [1064]
LIPH OTRGYLKL Definitive Altered Expression [1065]
LMNA OT3SG7ZR Definitive Altered Expression [1066]
LORICRIN OTFRPVEO Definitive Genetic Variation [1067]
LSAMP OTYXVQX2 Definitive Posttranslational Modification [1063]
LUM OTSRC874 Definitive Altered Expression [1068]
MACC1 OTV3DLX0 Definitive Biomarker [1069]
MAP2K3 OTI2OREX Definitive Biomarker [1070]
MEGF8 OT5G38CH Definitive Altered Expression [1071]
MOK OTQK7M9V Definitive Biomarker [1072]
MX2 OT05NF37 Definitive Biomarker [1073]
NEO1 OTGJ1997 Definitive Altered Expression [403]
PDC OT1UUVYY Definitive Biomarker [1074]
PDCD6 OT2YA5M8 Definitive Biomarker [1075]
PLAC8 OT3SYRUJ Definitive Biomarker [1076]
PLS1 OTWURB8U Definitive Biomarker [1077]
PPA1 OTHZK1QB Definitive Altered Expression [472]
PRKD2 OTIFSVI8 Definitive Altered Expression [903]
PRR13 OTXPP37T Definitive Biomarker [1042]
PRSS55 OTXXWI5Y Definitive Altered Expression [1042]
PSG2 OT2EIXAI Definitive Biomarker [55]
PTOV1 OT94WT5X Definitive Biomarker [1078]
RAD9A OTJ3AJQU Definitive Genetic Variation [1079]
RBM5 OTCBWHHV Definitive Biomarker [1080]
REG1A OTMHUH1D Definitive Altered Expression [440]
RIN1 OTPBROUD Definitive Altered Expression [1081]
RPL19 OT33LM66 Definitive Biomarker [1082]
S100A14 OTVFJJ91 Definitive Altered Expression [1083]
S100A16 OT3ERKQI Definitive Altered Expression [1084]
SEPHS2 OTTFXROR Definitive Biomarker [1085]
SERINC2 OTZ039U0 Definitive Altered Expression [1086]
SERPINB4 OT88LHZ8 Definitive Biomarker [1087]
SH3GLB1 OTAZ5OP8 Definitive Altered Expression [1028]
SLC12A9 OTR7VRAK Definitive Altered Expression [1088]
SNAI1 OTDPYAMC Definitive Altered Expression [1089]
SOX9 OTVDJFGN Definitive Altered Expression [1090]
SPAG4 OTVXS2SM Definitive Altered Expression [1091]
SPZ1 OTQH8HJ5 Definitive Altered Expression [1042]
SUB1 OTK71JYU Definitive Altered Expression [525]
SULF1 OTJCNCO0 Definitive Altered Expression [1092]
SUPT20H OTTMC0LH Definitive Biomarker [449]
SYT1 OTVTPOI6 Definitive Biomarker [1055]
TBX2 OTTOT7A9 Definitive Altered Expression [1093]
TLE5 OTEH0BFG Definitive Altered Expression [1094]
TMPRSS4 OTCCGY2K Definitive Altered Expression [1095]
TRAF2 OT1MEZZN Definitive Altered Expression [1096]
TRIT1 OTCU9FS5 Definitive Genetic Variation [1097]
TSHZ1 OTYQ9ECW Definitive Genetic Variation [1098]
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⏷ Show the Full List of 936 DOT(s)

References

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2 Carboplatin FDA Label
3 Paclitaxel FDA Label
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66 Deregulation of small non-coding RNAs at the DLK1-DIO3 imprinted locus predicts lung cancer patient outcome.Oncotarget. 2016 Dec 6;7(49):80957-80966. doi: 10.18632/oncotarget.13133.
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70 VEGFR3 inhibition chemosensitizes lung adenocarcinoma A549 cells in the tumor-associated macrophage microenvironment through upregulation of p53 and PTEN.Oncol Rep. 2017 Nov;38(5):2761-2773. doi: 10.3892/or.2017.5969. Epub 2017 Sep 19.
71 Assessment of folate receptor alpha and beta expression in selection of lung and pancreatic cancer patients for receptor targeted therapies.Oncotarget. 2017 Dec 15;9(4):4485-4495. doi: 10.18632/oncotarget.23321. eCollection 2018 Jan 12.
72 FUT4 is involved in PD-1-related immunosuppression and leads to worse survival in patients with operable lung adenocarcinoma.J Cancer Res Clin Oncol. 2019 Jan;145(1):65-76. doi: 10.1007/s00432-018-2761-y. Epub 2018 Oct 24.
73 AXL and GAS6 co-expression in lung adenocarcinoma as a prognostic classifier.Oncol Rep. 2017 Jun;37(6):3261-3269. doi: 10.3892/or.2017.5594. Epub 2017 Apr 21.
74 Differential expression of glypican-3 (GPC3) in lung squamous cell carcinoma and lung adenocarcinoma and its clinical significance.Genet Mol Res. 2015 Aug 28;14(3):10185-92. doi: 10.4238/2015.August.28.2.
75 EGFR-GRB2 Protein Colocalization Is a Prognostic Factor Unrelated to Overall EGFR Expression or EGFR Mutation in Lung Adenocarcinoma.J Thorac Oncol. 2016 Nov;11(11):1901-1911. doi: 10.1016/j.jtho.2016.06.025. Epub 2016 Jul 20.
76 Identification of urine biomarkers associated with lung adenocarcinoma.Oncotarget. 2017 Jun 13;8(24):38517-38529. doi: 10.18632/oncotarget.15870.
77 Whole-exome sequencing and immune profiling of early-stage lung adenocarcinoma with fully annotated clinical follow-up.Ann Oncol. 2017 Jan 1;28(1):75-82. doi: 10.1093/annonc/mdw436.
78 IB Kinase Is Required for Development and Progression of KRAS-Mutant Lung Adenocarcinoma.Cancer Res. 2018 Jun 1;78(11):2939-2951. doi: 10.1158/0008-5472.CAN-17-1944. Epub 2018 Mar 27.
79 IL12RB2 Polymorphisms correlate with risk of lung adenocarcinoma.Immunobiology. 2016 Feb;221(2):291-9. doi: 10.1016/j.imbio.2015.10.006. Epub 2015 Oct 29.
80 IMP3 Predicts Invasion and Prognosis in Human Lung Adenocarcinoma.Lung. 2016 Feb;194(1):137-46. doi: 10.1007/s00408-015-9829-0. Epub 2015 Nov 25.
81 RNAi screen identifies essential regulators of human brain metastasis-initiating cells.Acta Neuropathol. 2017 Dec;134(6):923-940. doi: 10.1007/s00401-017-1757-z. Epub 2017 Aug 1.
82 SH2B1 promotes epithelial-mesenchymal transition through the IRS1/-catenin signaling axis in lung adenocarcinoma.Mol Carcinog. 2018 May;57(5):640-652. doi: 10.1002/mc.22788. Epub 2018 Feb 20.
83 MAP3K3 expression in tumor cells and tumor-infiltrating lymphocytes is correlated with favorable patient survival in lung cancer.Sci Rep. 2015 Jun 19;5:11471. doi: 10.1038/srep11471.
84 MAP4K4 is a novel MAPK/ERK pathway regulator required for lung adenocarcinoma maintenance.Mol Oncol. 2017 Jun;11(6):628-639. doi: 10.1002/1878-0261.12055. Epub 2017 May 2.
85 ETS-1-mediated transcriptional up-regulation of CD44 is required for sphingosine-1-phosphate receptor subtype 3-stimulated chemotaxis.J Biol Chem. 2013 Nov 8;288(45):32126-32137. doi: 10.1074/jbc.M113.495218. Epub 2013 Sep 24.
86 Genomic rearrangements define lineage relationships between adjacent lepidic and invasive components in lung adenocarcinoma.Cancer Res. 2014 Jun 1;74(11):3157-67. doi: 10.1158/0008-5472.CAN-13-1727.
87 Matrix metalloproteinase-10 promotes Kras-mediated bronchio-alveolar stem cell expansion and lung cancer formation.PLoS One. 2011;6(10):e26439. doi: 10.1371/journal.pone.0026439. Epub 2011 Oct 17.
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89 High mesothelin expression in advanced lung adenocarcinoma is associated with KRAS mutations and a poor prognosis.Oncotarget. 2015 May 10;6(13):11694-703. doi: 10.18632/oncotarget.3429.
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476 PRAS40 promotes NF-B transcriptional activity through association with p65.Oncogenesis. 2017 Sep 25;6(9):e381. doi: 10.1038/oncsis.2017.80.
477 ALKBH3, a human AlkB homologue, contributes to cell survival in human non-small-cell lung cancer.Br J Cancer. 2011 Feb 15;104(4):700-6. doi: 10.1038/sj.bjc.6606012. Epub 2011 Feb 1.
478 FHIT loss-induced DNA damage creates optimal APOBEC substrates: Insights into APOBEC-mediated mutagenesis.Oncotarget. 2015 Feb 20;6(5):3409-19. doi: 10.18632/oncotarget.2636.
479 Upregulation of CISD2 augments ROS homeostasis and contributes to tumorigenesis and poor prognosis of lung adenocarcinoma.Sci Rep. 2017 Sep 19;7(1):11893. doi: 10.1038/s41598-017-12131-x.
480 Claudin 3, 4, and 15 expression in solid tumors of lung adenocarcinoma versus malignant pleural mesothelioma.Ann Diagn Pathol. 2015 Aug;19(4):193-7. doi: 10.1016/j.anndiagpath.2015.03.007. Epub 2015 Apr 14.
481 Claudin-5 regulates blood-brain barrier permeability by modifying brain microvascular endothelial cell proliferation, migration, and adhesion to prevent lung cancer metastasis.CNS Neurosci Ther. 2017 Dec;23(12):947-960. doi: 10.1111/cns.12764. Epub 2017 Sep 29.
482 Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5(p)15.33 TERT-CLPTM1Ll Region.J Thorac Oncol. 2019 Aug;14(8):1360-1369. doi: 10.1016/j.jtho.2019.04.008. Epub 2019 Apr 19.
483 Compound haploinsufficiency of Dok2 and Dusp4 promotes lung tumorigenesis.J Clin Invest. 2019 Jan 2;129(1):215-222. doi: 10.1172/JCI99699. Epub 2018 Nov 26.
484 Downregulation of EMX2 is associated with clinical outcomes in lung adenocarcinoma patients.Clin Lung Cancer. 2011 Jul;12(4):237-44. doi: 10.1016/j.cllc.2011.03.025. Epub 2011 Apr 24.
485 ERP44 inhibits human lung cancer cell migration mainly via IP3R2.Aging (Albany NY). 2016 Jun;8(6):1276-86. doi: 10.18632/aging.100984.
486 Epithelial Splicing Regulatory Protein 1 Inhibits the Invasion and Metastasis of Lung Adenocarcinoma.Am J Pathol. 2018 Aug;188(8):1882-1894. doi: 10.1016/j.ajpath.2018.04.012. Epub 2018 May 24.
487 Altered expression of the ERM proteins in lung adenocarcinoma.Lab Invest. 2000 Nov;80(11):1643-50. doi: 10.1038/labinvest.3780174.
488 Elevated FAM83A expression predicts poorer clincal outcome in lung adenocarcinoma.Cancer Biomark. 2019;26(3):367-373. doi: 10.3233/CBM-190520.
489 Epigenetic loss of putative tumor suppressor SFRP3 correlates with poor prognosis of lung adenocarcinoma patients.Epigenetics. 2018;13(3):214-227. doi: 10.1080/15592294.2016.1229730. Epub 2018 Apr 18.
490 A retinoid responsive cytokine gene, MK, is preferentially expressed in the proximal tubules of the kidney and human tumor cell lines.Am J Pathol. 1993 Feb;142(2):425-31.
491 Genome-wide DNA Methylation Analysis Reveals GABBR2 as a Novel Epigenetic Target for EGFR 19 Deletion Lung Adenocarcinoma with Induction Erlotinib Treatment.Clin Cancer Res. 2017 Sep 1;23(17):5003-5014. doi: 10.1158/1078-0432.CCR-16-2688. Epub 2017 May 10.
492 FAM198B Is Associated with Prolonged Survival and Inhibits Metastasis in Lung Adenocarcinoma via Blockage of ERK-Mediated MMP-1 Expression.Clin Cancer Res. 2018 Feb 15;24(4):916-926. doi: 10.1158/1078-0432.CCR-17-1347. Epub 2017 Dec 7.
493 Overexpression of geranylgeranyl diphosphate synthase contributes to tumour metastasis and correlates with poor prognosis of lung adenocarcinoma.J Cell Mol Med. 2018 Apr;22(4):2177-2189. doi: 10.1111/jcmm.13493. Epub 2018 Jan 29.
494 Glypican-1 immunohistochemistry is a novel marker to differentiate epithelioid mesothelioma from lung adenocarcinoma.Mod Pathol. 2018 May;31(5):809-815. doi: 10.1038/modpathol.2017.190. Epub 2018 Jan 12.
495 Carboxamide analog ITR-284 evokes apoptosis and inhibits migration ability in human lung adenocarcinoma A549 cells.Oncol Rep. 2017 Mar;37(3):1786-1792. doi: 10.3892/or.2017.5374. Epub 2017 Jan 16.
496 TOX3 is a favorable prognostic indicator and potential immunomodulatory factor in lung adenocarcinoma.Oncol Lett. 2019 Oct;18(4):4144-4152. doi: 10.3892/ol.2019.10748. Epub 2019 Aug 16.
497 HHLA2, a New Immune Checkpoint Member of the B7 Family, Is Widely Expressed in Human Lung Cancer and Associated with EGFR Mutational Status.Clin Cancer Res. 2017 Feb 1;23(3):825-832. doi: 10.1158/1078-0432.CCR-15-3071. Epub 2016 Aug 23.
498 Acetylated HOXB9 at lysine 27 is of differential diagnostic value in patients with pancreatic ductal adenocarcinoma.Front Med. 2020 Feb;14(1):91-100. doi: 10.1007/s11684-019-0696-6. Epub 2019 Aug 2.
499 HOXC10 Promotes the Metastasis of Human Lung Adenocarcinoma and Indicates Poor Survival Outcome.Front Physiol. 2017 Aug 2;8:557. doi: 10.3389/fphys.2017.00557. eCollection 2017.
500 Insulin-like growth factor binding protein-4 gene silencing in lung adenocarcinomas.Pathol Int. 2011 Jan;61(1):19-27. doi: 10.1111/j.1440-1827.2010.02612.x. Epub 2010 Nov 3.
501 The Prognostic Impact of Jumonji Domain-containing 2B in Patients with Resected Lung Adenocarcinoma.Anticancer Res. 2016 Sep;36(9):4841-6. doi: 10.21873/anticanres.11046.
502 The motor protein KIF14 inhibits tumor growth and cancer metastasis in lung adenocarcinoma.PLoS One. 2013 Apr 23;8(4):e61664. doi: 10.1371/journal.pone.0061664. Print 2013.
503 An important role for Myb-MuvB and its target gene KIF23 in a mouse model of lung adenocarcinoma.Oncogene. 2017 Jan 5;36(1):110-121. doi: 10.1038/onc.2016.181. Epub 2016 May 23.
504 Oncogenic Function of a KIF5B-MET Fusion Variant in Non-Small Cell Lung Cancer.Neoplasia. 2018 Aug;20(8):838-847. doi: 10.1016/j.neo.2018.06.007. Epub 2018 Jul 13.
505 Krppel-like factor 17 inhibits urokinase plasminogen activator gene expression to suppress cell invasion through the Src/p38/ MAPK signaling pathway in human lung adenocarcionma.Oncotarget. 2017 Jun 13;8(24):38743-38754. doi: 10.18632/oncotarget.17020.
506 LAT1 expression in normal lung and in atypical adenomatous hyperplasia and adenocarcinoma of the lung.Virchows Arch. 2006 Feb;448(2):142-50. doi: 10.1007/s00428-005-0063-7. Epub 2005 Sep 21.
507 Neuroglobin and myoglobin in non-small cell lung cancer: expression, regulation and prognosis.Lung Cancer. 2011 Dec;74(3):411-8. doi: 10.1016/j.lungcan.2011.05.001. Epub 2011 Jun 2.
508 Expression of MUC1, MUC2, MUC5AC, and MUC6 in atypical adenomatous hyperplasia, bronchioloalveolar carcinoma, adenocarcinoma with mixed subtypes, and mucinous bronchioloalveolar carcinoma of the lung.Am J Clin Pathol. 2004 May;121(5):644-53. doi: 10.1309/U4WG-E9EB-FJN6-CM8R.
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510 OLA1 contributes to epithelial-mesenchymal transition in lung cancer by modulating the GSK3/snail/E-cadherin signaling.Oncotarget. 2016 Mar 1;7(9):10402-13. doi: 10.18632/oncotarget.7224.
511 Prognostic significance of combining immunohistochemical markers for cancer-associated fibroblasts in lung adenocarcinoma tissue.Virchows Arch. 2019 Aug;475(2):181-189. doi: 10.1007/s00428-019-02587-9. Epub 2019 May 27.
512 Plakophilin 3 oncogene as prognostic marker and therapeutic target for lung cancer.Cancer Res. 2005 Aug 15;65(16):7102-10. doi: 10.1158/0008-5472.CAN-04-1877.
513 Podocalyxin influences malignant potential by controlling epithelial-mesenchymal transition in lung adenocarcinoma.Cancer Sci. 2017 Mar;108(3):528-535. doi: 10.1111/cas.13142.
514 The role of Necl-5 in the invasive activity of lung adenocarcinoma.Exp Mol Pathol. 2013 Apr;94(2):330-5. doi: 10.1016/j.yexmp.2012.12.003. Epub 2012 Dec 28.
515 Differential expression of RAB5A in human lung adenocarcinoma cells with different metastasis potential.Clin Exp Metastasis. 1999 May;17(3):213-9. doi: 10.1023/a:1006617016451.
516 RBM10 truncation in astroblastoma in a patient with history of mandibular ameloblastoma: A case report.Cancer Genet. 2019 Feb;231-232:41-45. doi: 10.1016/j.cancergen.2019.01.001. Epub 2019 Jan 9.
517 Overexpression of regulator of G protein signaling 11 promotes cell migration and associates with advanced stages and aggressiveness of lung adenocarcinoma.Oncotarget. 2016 May 24;7(21):31122-36. doi: 10.18632/oncotarget.8860.
518 Inhibition of rhotekin exhibits antitumor effects in lung cancer cells.Oncol Rep. 2016 May;35(5):2529-34. doi: 10.3892/or.2016.4634. Epub 2016 Feb 24.
519 Identification and Characterization of Oncogenic SOS1 Mutations in Lung Adenocarcinoma.Mol Cancer Res. 2019 Apr;17(4):1002-1012. doi: 10.1158/1541-7786.MCR-18-0316. Epub 2019 Jan 11.
520 SPANXA suppresses EMT by inhibiting c-JUN/SNAI2 signaling in lung adenocarcinoma.Oncotarget. 2016 Jul 12;7(28):44417-44429. doi: 10.18632/oncotarget.10088.
521 Identification of Methylation-Driven, Differentially Expressed STXBP6 as a Novel Biomarker in Lung Adenocarcinoma.Sci Rep. 2017 Feb 15;7:42573. doi: 10.1038/srep42573.
522 Overexpression of TNKS1BP1 in lung cancers and its involvement in homologous recombination pathway of DNA double-strand breaks.Cancer Med. 2017 Feb;6(2):483-493. doi: 10.1002/cam4.995. Epub 2017 Jan 6.
523 AHNAK Loss in Mice Promotes Type II Pneumocyte Hyperplasia and Lung Tumor Development.Mol Cancer Res. 2018 Aug;16(8):1287-1298. doi: 10.1158/1541-7786.MCR-17-0726. Epub 2018 May 3.
524 DAL-1 attenuates epithelial to mesenchymal transition and metastasis by suppressing HSPA5 expression in non-small cell lung cancer.Oncol Rep. 2017 Nov;38(5):3103-3113. doi: 10.3892/or.2017.6000. Epub 2017 Sep 26.
525 Adenovirus-Mediated Expression of the p14 Fusion-Associated Small Transmembrane Protein Promotes Cancer Cell Fusion and Apoptosis In Vitro but Does Not Provide Therapeutic Efficacy in a Xenograft Mouse Model of Cancer.PLoS One. 2016 Mar 17;11(3):e0151516. doi: 10.1371/journal.pone.0151516. eCollection 2016.
526 Screening for transcription factors and their regulatory small molecules involved in regulating the functions of CL1-5 cancer cells under the effects of macrophage-conditioned medium.Oncol Rep. 2014 Mar;31(3):1323-33. doi: 10.3892/or.2013.2937. Epub 2013 Dec 20.
527 Expression of OPN3 in lung adenocarcinoma promotes epithelial-mesenchymal transition and tumor metastasis.Thorac Cancer. 2020 Feb;11(2):286-294. doi: 10.1111/1759-7714.13254. Epub 2019 Dec 5.
528 Plasma selenoprotein P concentration and lung cancer risk: results from a case-control study nested within the Shanghai Men's Health Study.Carcinogenesis. 2018 Dec 13;39(11):1352-1358. doi: 10.1093/carcin/bgy103.
529 Down-regulation of SIX3 is associated with clinical outcome in lung adenocarcinoma.PLoS One. 2013 Aug 16;8(8):e71816. doi: 10.1371/journal.pone.0071816. eCollection 2013.
530 The ACIN1 gene is hypermethylated in early stage lung adenocarcinoma.J Thorac Oncol. 2006 Feb;1(2):160-7.
531 Actinin-4 protein overexpression as a predictive biomarker in adjuvant chemotherapy for resected lung adenocarcinoma.Biomark Med. 2017 Sep;11(9):721-731. doi: 10.2217/bmm-2017-0150. Epub 2017 Jun 29.
532 Expression of the Arp11 gene suppresses the tumorigenicity of PC-14 human lung adenocarcinoma cells.Biochem Biophys Res Commun. 2003 Dec 26;312(4):889-96. doi: 10.1016/j.bbrc.2003.10.200.
533 Development of selective inhibitors for human aldehyde dehydrogenase 3A1 (ALDH3A1) for the enhancement of cyclophosphamide cytotoxicity.Chembiochem. 2014 Mar 21;15(5):701-12. doi: 10.1002/cbic.201300625.
534 Comparative proteomics and global genome-wide expression data implicate role of ARMC8 in lung cancer.Asian Pac J Cancer Prev. 2015;16(9):3691-6. doi: 10.7314/apjcp.2015.16.9.3691.
535 shRNA-mediated knockdown of Bmi-1 inhibit lung adenocarcinoma cell migration and metastasis.Lung Cancer. 2012 Jul;77(1):24-30. doi: 10.1016/j.lungcan.2012.02.015. Epub 2012 Mar 13.
536 Clinical Implications of the BIM Deletion Polymorphism in Advanced Lung Adenocarcinoma Treated With Gefitinib.Clin Lung Cancer. 2018 Jul;19(4):e431-e438. doi: 10.1016/j.cllc.2018.02.007. Epub 2018 Feb 19.
537 Diagnostic and prognostic value of the BEX family in lung adenocarcinoma.Oncol Lett. 2019 Nov;18(5):5523-5533. doi: 10.3892/ol.2019.10905. Epub 2019 Sep 20.
538 BHLHB3: a candidate tumor suppressor in lung cancer.Oncogene. 2008 Jun 12;27(26):3761-4. doi: 10.1038/sj.onc.1211038. Epub 2008 Jan 28.
539 BRMS1 Expression in Surgically Resected Lung Adenocarcinoma Predicts Future Metastases and IsAssociated with a Poor Prognosis.J Thorac Oncol. 2018 Jan;13(1):73-84. doi: 10.1016/j.jtho.2017.10.006. Epub 2017 Oct 31.
540 Tenascin XB Is a Novel Diagnostic Marker for Malignant Mesothelioma.Anticancer Res. 2019 Feb;39(2):627-633. doi: 10.21873/anticanres.13156.
541 HP1 Promotes Lung Adenocarcinoma by Downregulating the Transcription-Repressive Regulators NCOR2 and ZBTB7A.Cancer Res. 2018 Jul 15;78(14):3834-3848. doi: 10.1158/0008-5472.CAN-17-3571. Epub 2018 May 15.
542 High CC chemokine receptor 7 expression improves postoperative prognosis of lung adenocarcinoma patients.Br J Cancer. 2013 Sep 3;109(5):1100-8. doi: 10.1038/bjc.2013.440. Epub 2013 Aug 6.
543 CDCA2 promotes the proliferation of colorectal cancer cells by activating the AKT/CCND1 pathway in vitro and in vivo.BMC Cancer. 2019 Jun 13;19(1):576. doi: 10.1186/s12885-019-5793-z.
544 Reduced CENPU expression inhibits lung adenocarcinoma cell proliferation and migration through PI3K/AKT signaling.Biosci Biotechnol Biochem. 2019 Jun;83(6):1077-1084. doi: 10.1080/09168451.2019.1588094. Epub 2019 Mar 8.
545 ALK-rearranged squamous cell lung carcinoma responding to crizotinib: A missing link in the field of non-small cell lung cancer?.Lung Cancer. 2016 Jan;91:67-9. doi: 10.1016/j.lungcan.2015.11.010. Epub 2015 Nov 10.
546 The axis IL-10/claudin-10 is implicated in the modulation of aggressiveness of melanoma cells by B-1 lymphocytes.PLoS One. 2017 Nov 16;12(11):e0187333. doi: 10.1371/journal.pone.0187333. eCollection 2017.
547 Proteome analysis for downstream targets of oncogenic KRAS--the potential participation of CLIC4 in carcinogenesis in the lung.PLoS One. 2014 Feb 4;9(2):e87193. doi: 10.1371/journal.pone.0087193. eCollection 2014.
548 CXCR2 expression in tumor cells is a poor prognostic factor and promotes invasion and metastasis in lung adenocarcinoma.Cancer Res. 2013 Jan 15;73(2):571-82. doi: 10.1158/0008-5472.CAN-12-0263. Epub 2012 Nov 30.
549 TTF-1/NKX2-1 binds to DDB1 and confers replication stress resistance to lung adenocarcinomas.Oncogene. 2017 Jun 29;36(26):3740-3748. doi: 10.1038/onc.2016.524. Epub 2017 Feb 13.
550 Identification of putative oncogenes in lung adenocarcinoma by a comprehensive functional genomic approach.Oncogene. 2006 Apr 27;25(18):2628-35. doi: 10.1038/sj.onc.1209289.
551 Early Steps of Jaagsiekte Sheep Retrovirus-Mediated Cell Transformation Involve the Interaction between Env and the RALBP1 Cellular Protein.J Virol. 2015 Aug;89(16):8462-73. doi: 10.1128/JVI.00590-15. Epub 2015 Jun 3.
552 Uncovering synthetic lethal interactions for therapeutic targets and predictive markers in lung adenocarcinoma.Oncotarget. 2016 Nov 8;7(45):73664-73680. doi: 10.18632/oncotarget.12046.
553 FLOT1 promotes tumor development, induces epithelial-mesenchymal transition, and modulates the cell cycle by regulating the Erk/Akt signaling pathway in lung adenocarcinoma.Thorac Cancer. 2019 Apr;10(4):909-917. doi: 10.1111/1759-7714.13027. Epub 2019 Mar 5.
554 miR-133 involves in lung adenocarcinoma cell metastasis by targeting FLOT2.Artif Cells Nanomed Biotechnol. 2018 Mar;46(2):224-230. doi: 10.1080/21691401.2017.1324467. Epub 2017 May 14.
555 GATA6-positive lung adenocarcinomas are associated with invasive mucinous adenocarcinoma morphology, hepatocyte nuclear factor 4 expression, and KRAS mutations.Histopathology. 2018 Jul;73(1):38-48. doi: 10.1111/his.13500. Epub 2018 Apr 17.
556 High GINS2 transcript level predicts poor prognosis and correlates with high histological grade and endocrine therapy resistance through mammary cancer stem cells in breast cancer patients.Breast Cancer Res Treat. 2014 Nov;148(2):423-36. doi: 10.1007/s10549-014-3172-7. Epub 2014 Oct 28.
557 GPX2 suppression of H(2)O(2) stress regulates cervical cancer metastasis and apoptosis via activation of the -catenin-WNT pathway.Onco Targets Ther. 2019 Aug 19;12:6639-6651. doi: 10.2147/OTT.S208781. eCollection 2019.
558 Effects of selenium supplementation on expression of glutathione peroxidase isoforms in cultured human lung adenocarcinoma cell lines. Lung Cancer. 2007 Jan;55(1):35-42.
559 Hypermethylation of the G protein-coupled receptor kinase 6 (GRK6) promoter inhibits binding of C/EBP, and GRK6 knockdown promotes cell migration and invasion in lung adenocarcinoma cells.FEBS Open Bio. 2019 Mar 19;9(4):605-617. doi: 10.1002/2211-5463.12606. eCollection 2019 Apr.
560 Neuropeptide gastrin-releasing peptide induces PI3K/reactive oxygen species-dependent migration in lung adenocarcinoma cells.Tumour Biol. 2017 Mar;39(3):1010428317694321. doi: 10.1177/1010428317694321.
561 HOXA9 methylation and blood vessel invasion in FFPE tissues for prognostic stratification of stage I lung adenocarcinoma patients.Lung Cancer. 2018 Aug;122:151-159. doi: 10.1016/j.lungcan.2018.05.021. Epub 2018 May 22.
562 Identification and validation of candidate epigenetic biomarkers in lung adenocarcinoma.Sci Rep. 2016 Oct 26;6:35807. doi: 10.1038/srep35807.
563 Inhibitor of DNA binding 3 reverses cisplatin resistance in human lung adenocarcinoma cells by regulating the PI3K/Akt pathway.Oncol Lett. 2018 Aug;16(2):1634-1640. doi: 10.3892/ol.2018.8849. Epub 2018 May 31.
564 KIF18B as a regulator in microtubule movement accelerates tumor progression and triggers poor outcome in lung adenocarcinoma.Tissue Cell. 2019 Dec;61:44-50. doi: 10.1016/j.tice.2019.09.001. Epub 2019 Sep 3.
565 KLF15 suppresses cell growth and predicts prognosis in lung adenocarcinoma.Biomed Pharmacother. 2018 Oct;106:672-677. doi: 10.1016/j.biopha.2018.07.006. Epub 2018 Jul 11.
566 Targeting the FOXO1/KLF6 axis regulates EGFR signaling and treatment response.J Clin Invest. 2012 Jul;122(7):2637-51. doi: 10.1172/JCI62058. Epub 2012 Jun 1.
567 miR-1236-3p suppresses the migration and invasion by targeting KLF8 in lung adenocarcinoma A549cells.Biochem Biophys Res Commun. 2017 Oct 21;492(3):461-467. doi: 10.1016/j.bbrc.2017.08.074. Epub 2017 Aug 24.
568 The drs tumor suppressor regulates glucose metabolism via lactate dehydrogenase-B.Mol Carcinog. 2016 Jan;55(1):52-63. doi: 10.1002/mc.22258. Epub 2015 Jan 24.
569 MicroRNA-381 inhibits lung adenocarcinoma cell biological progression by directly targeting LMO3 through regulation of the PI3K/Akt signaling pathway and epithelial-to-mesenchymal transition.Eur Rev Med Pharmacol Sci. 2019 Oct;23(19):8411-8421. doi: 10.26355/eurrev_201910_19152.
570 Targeted Sequencing Analysis of Pulmonary Adenocarcinoma with Multiple Synchronous Ground-Glass/Lepidic Nodules.J Thorac Oncol. 2018 Nov;13(11):1776-1783. doi: 10.1016/j.jtho.2018.07.097. Epub 2018 Aug 16.
571 Expression of the multidrug-resistance-associated protein (MRP) gene in human colorectal, gastric and non-small-cell lung carcinomas.Int J Cancer. 1996 Apr 10;66(2):274-9. doi: 10.1002/(SICI)1097-0215(19960410)66:2<274::AID-IJC23>3.0.CO;2-B.
572 Prognostic significance of minichromosome maintenance mRNA expression in human lung adenocarcinoma.Oncol Rep. 2019 Dec;42(6):2279-2292. doi: 10.3892/or.2019.7330. Epub 2019 Sep 23.
573 Gender difference in the activity but not expression of estrogen receptors alpha and beta in human lung adenocarcinoma cells.Endocr Relat Cancer. 2006 Mar;13(1):113-34. doi: 10.1677/erc.1.01118.
574 In vivo and in vitro effects of hyperplasia suppressor gene on the proliferation and apoptosis of lung adenocarcinoma A549 cells.Biosci Rep. 2018 Oct 2;38(5):BSR20180391. doi: 10.1042/BSR20180391. Print 2018 Oct 31.
575 MFSD2A is a novel lung tumor suppressor gene modulating cell cycle and matrix attachment.Mol Cancer. 2010 Mar 17;9:62. doi: 10.1186/1476-4598-9-62.
576 Association of p73 G4C14-to-A4T14 polymorphism at exon 2 with the response of human lung adenocarcinoma cell lines to chemotherapy.Cell Biol Int. 2010 Jan 25;34(2):185-8. doi: 10.1042/CBI20090148.
577 Mutational analysis of the DAL-1/4.1B tumour-suppressor gene locus in meningiomas.Int J Mol Med. 2005 Oct;16(4):771-4.
578 Long non-coding RNA MUC5B-AS1 promotes metastasis through mutually regulating MUC5B expression in lung adenocarcinoma.Cell Death Dis. 2018 May 1;9(5):450. doi: 10.1038/s41419-018-0472-6.
579 MYBPH, a transcriptional target of TTF-1, inhibits ROCK1, and reduces cell motility and metastasis.EMBO J. 2012 Jan 18;31(2):481-93. doi: 10.1038/emboj.2011.416. Epub 2011 Nov 15.
580 A new polymorphism (Ser362Thr) of the L-myc gene is not associated with lung adenocarcinoma risk and prognosis.Eur J Cancer Prev. 2004 Feb;13(1):87-9. doi: 10.1097/00008469-200402000-00014.
581 Expression of ERCC1, TYMS, RRM1, TUBB3, non-muscle myosin II, myoglobin and MyoD1 in lung adenocarcinoma pleural effusions predicts survival in patients receiving platinum-based chemotherapy.Mol Med Rep. 2015 May;11(5):3523-32. doi: 10.3892/mmr.2014.3141. Epub 2014 Dec 30.
582 Two-stage induced differentiation of OCT4+/Nanog+ stem-like cells in lung adenocarcinoma.Oncotarget. 2016 Oct 18;7(42):68360-68370. doi: 10.18632/oncotarget.11721.
583 Neuronatin expression and its clinicopathological significance in pulmonary non-small cell carcinoma.J Thorac Oncol. 2007 Sep;2(9):796-801. doi: 10.1097/JTO.0b013e318145af5e.
584 Identification of a panel of sensitive and specific DNA methylation markers for lung adenocarcinoma.Mol Cancer. 2007 Oct 29;6:70. doi: 10.1186/1476-4598-6-70.
585 Identification of protein expression alterations in gefitinib-resistant human lung adenocarcinoma: PCNT and mPR play key roles in the development of gefitinib-associated resistance. Toxicol Appl Pharmacol. 2015 Nov 1;288(3):359-73. doi: 10.1016/j.taap.2015.08.008. Epub 2015 Aug 20.
586 Pleiomorphic adenoma gene-like 2 expression is associated with the development of lung adenocarcinoma and emphysema.Lung Cancer. 2011 Oct;74(1):12-24. doi: 10.1016/j.lungcan.2011.02.006. Epub 2011 Mar 11.
587 MiR-1-3p Inhibits Lung Adenocarcinoma Cell Tumorigenesis via Targeting Protein Regulator of Cytokinesis 1.Front Oncol. 2019 Mar 1;9:120. doi: 10.3389/fonc.2019.00120. eCollection 2019.
588 Systematic identification of lincRNA-based prognostic biomarkers by integrating lincRNA expression and copy number variation in lung adenocarcinoma.Int J Cancer. 2019 Apr 1;144(7):1723-1734. doi: 10.1002/ijc.31865. Epub 2018 Dec 12.
589 Tobacco smoke activates human papillomavirus 16 p97 promoter and cooperates with high-risk E6/E7 for oxidative DNA damage in lung cells.PLoS One. 2015 Apr 1;10(4):e0123029. doi: 10.1371/journal.pone.0123029. eCollection 2015.
590 Circular RNA cMras inhibits lung adenocarcinoma progression via modulating miR-567/PTPRG regulatory pathway.Cell Prolif. 2019 May;52(3):e12610. doi: 10.1111/cpr.12610. Epub 2019 Apr 22.
591 A regulatory circuit of circ-MTO1/miR-17/QKI-5 inhibits the proliferation of lung adenocarcinoma.Cancer Biol Ther. 2019;20(8):1127-1135. doi: 10.1080/15384047.2019.1598762. Epub 2019 Apr 12.
592 RNA-binding motif protein 47 inhibits Nrf2 activity to suppress tumor growth in lung adenocarcinoma.Oncogene. 2017 Aug 31;36(35):5083. doi: 10.1038/onc.2017.191. Epub 2017 Jun 12.
593 Correction: S100A9+ MDSC and TAM-mediated EGFR-TKI resistance in lung adenocarcinoma: the role of RELB.Oncotarget. 2018 Jul 31;9(59):31559. doi: 10.18632/oncotarget.25943. eCollection 2018 Jul 31.
594 Prolonged survival of patients with colorectal cancer is associated with a higher regucalcin gene expression: Overexpression of regucalcin suppresses the growth of human colorectal carcinoma cells invitro.Int J Oncol. 2018 Sep;53(3):1313-1322. doi: 10.3892/ijo.2018.4458. Epub 2018 Jun 28.
595 Biochemical Classification of Disease-associated Mutants of RAS-like Protein Expressed in Many Tissues (RIT1).J Biol Chem. 2016 Jul 22;291(30):15641-52. doi: 10.1074/jbc.M116.714196. Epub 2016 May 18.
596 Decreased expression of RPS15A suppresses proliferation of lung cancer cells.Tumour Biol. 2015 Sep;36(9):6733-40. doi: 10.1007/s13277-015-3371-9. Epub 2015 Apr 3.
597 Tumor Suppressor Activity of Selenbp1, a Direct Nkx2-1 Target, in Lung Adenocarcinoma.Mol Cancer Res. 2018 Nov;16(11):1737-1749. doi: 10.1158/1541-7786.MCR-18-0392. Epub 2018 Jul 12.
598 Germline SFTPA1 mutation in familial idiopathic interstitial pneumonia and lung cancer.Hum Mol Genet. 2016 Apr 15;25(8):1457-67. doi: 10.1093/hmg/ddw014. Epub 2016 Jan 19.
599 The Expression of the Ubiquitin Ligase SIAH2 (Seven In Absentia Homolog 2) Is Increased in Human Lung Cancer.PLoS One. 2015 Nov 18;10(11):e0143376. doi: 10.1371/journal.pone.0143376. eCollection 2015.
600 Effects of Slit3 silencing on the invasive ability of lung carcinoma A549 cells.Oncol Rep. 2015 Aug;34(2):952-60. doi: 10.3892/or.2015.4031. Epub 2015 Jun 5.
601 Systematic In Vivo Inactivation of Chromatin-Regulating Enzymes Identifies Setd2 as a Potent Tumor Suppressor in Lung Adenocarcinoma.Cancer Res. 2017 Apr 1;77(7):1719-1729. doi: 10.1158/0008-5472.CAN-16-2159. Epub 2017 Feb 15.
602 Inactivation of SMARCA2 by promoter hypermethylation drives lung cancer development.Gene. 2019 Mar 1;687:193-199. doi: 10.1016/j.gene.2018.11.032. Epub 2018 Nov 14.
603 The genomic alterations of lung adenocarcinoma and lung squamous cell carcinoma can explain the differences of their overall survival rates.J Cell Physiol. 2019 Jul;234(7):10918-10925. doi: 10.1002/jcp.27917. Epub 2018 Dec 13.
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605 Genome-wide investigation of the clinical significance and prospective molecular mechanism of minichromosome maintenance protein family genes in patients with Lung Adenocarcinoma.PLoS One. 2019 Jul 19;14(7):e0219467. doi: 10.1371/journal.pone.0219467. eCollection 2019.
606 Identification of alternative splicing events regulated by the oncogenic factor SRSF1 in lung cancer.Cancer Res. 2014 Feb 15;74(4):1105-15. doi: 10.1158/0008-5472.CAN-13-1481. Epub 2013 Dec 26.
607 LKB1 and Tumor Metabolism: The Interplay of Immune and Angiogenic Microenvironment in Lung Cancer.Int J Mol Sci. 2019 Apr 16;20(8):1874. doi: 10.3390/ijms20081874.
608 TRB3 interacts with ERK and JNK and contributes to the proliferation, apoptosis, and migration of lung adenocarcinoma cells.J Cell Physiol. 2020 Jan;235(1):538-547. doi: 10.1002/jcp.28993. Epub 2019 Jun 29.
609 Exploiting FAsting-mimicking Diet and MEtformin to Improve the Efficacy of Platinum-pemetrexed Chemotherapy in Advanced LKB1-inactivated Lung Adenocarcinoma: The FAME Trial.Clin Lung Cancer. 2019 May;20(3):e413-e417. doi: 10.1016/j.cllc.2018.12.011. Epub 2018 Dec 19.
610 Methyl-CpG Binding Domain Protein 2 Inhibits the Malignant Characteristic of Lung Adenocarcinoma through the Epigenetic Modulation of 10 to 11 Translocation 1 and miR-200s.Am J Pathol. 2019 May;189(5):1065-1076. doi: 10.1016/j.ajpath.2019.01.010. Epub 2019 Feb 5.
611 Strong invitro and vivo cytotoxicity of novel organoplatinum(II) complexes with quinoline-coumarin derivatives.Eur J Med Chem. 2019 Dec 15;184:111751. doi: 10.1016/j.ejmech.2019.111751. Epub 2019 Oct 2.
612 Smad3-related miRNAs regulated oncogenic TRIB2 promoter activity to effectively suppress lung adenocarcinoma growth.Cell Death Dis. 2016 Dec 22;7(12):e2528. doi: 10.1038/cddis.2016.432.
613 Elevated TRIM23 expression predicts cisplatin resistance in lung adenocarcinoma.Cancer Sci. 2020 Feb;111(2):637-646. doi: 10.1111/cas.14226. Epub 2020 Jan 17.
614 Deficiency of Functional Iron-Sulfur Domains in ABCE1 Inhibits the Proliferation and Migration of Lung Adenocarcinomas By Regulating the Biogenesis of Beta-Actin In Vitro.Cell Physiol Biochem. 2017;44(2):554-566. doi: 10.1159/000485090. Epub 2017 Nov 17.
615 Human alpha beta hydrolase domain containing protein 11 and its yeast homolog are lipid hydrolases.Biochem Biophys Res Commun. 2017 Jun 10;487(4):875-880. doi: 10.1016/j.bbrc.2017.04.145. Epub 2017 Apr 29.
616 Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations.Lancet Respir Med. 2019 Oct;7(10):881-891. doi: 10.1016/S2213-2600(19)30144-4. Epub 2019 Jul 17.
617 Selective Inhibition of ADAM28 Suppresses Lung Carcinoma Cell Growth and Metastasis.Mol Cancer Ther. 2018 Nov;17(11):2427-2438. doi: 10.1158/1535-7163.MCT-17-1198. Epub 2018 Sep 6.
618 Global Transcriptome Analysis of RNA Abundance Regulation by ADAR in Lung Adenocarcinoma.EBioMedicine. 2018 Jan;27:167-175. doi: 10.1016/j.ebiom.2017.12.005. Epub 2017 Dec 6.
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624 Long noncoding RNA ZFPM2-AS1 is involved in lung adenocarcinoma via miR-511-3p/AFF4 pathway.J Cell Biochem. 2020 Mar;121(3):2534-2542. doi: 10.1002/jcb.29476. Epub 2019 Nov 6.
625 Overexpression of human Argonaute2 inhibits cell and tumor growth.Biochim Biophys Acta. 2013 Mar;1830(3):2553-61. doi: 10.1016/j.bbagen.2012.11.013.
626 A co-expressed gene status of adenylate kinase 1/4 reveals prognostic gene signature associated with prognosis and sensitivity to EGFR targeted therapy in lung adenocarcinoma.Sci Rep. 2019 Aug 23;9(1):12329. doi: 10.1038/s41598-019-48243-9.
627 Adenylate kinase 4 modulates oxidative stress and stabilizes HIF-1 to drive lung adenocarcinoma metastasis.J Hematol Oncol. 2019 Jan 29;12(1):12. doi: 10.1186/s13045-019-0698-5.
628 Targeting USP22 Suppresses Tumorigenicity and Enhances Cisplatin Sensitivity Through ALDH1A3 Downregulation in Cancer-Initiating Cells from Lung Adenocarcinoma.Mol Cancer Res. 2018 Jul;16(7):1161-1171. doi: 10.1158/1541-7786.MCR-18-0042. Epub 2018 May 2.
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630 Identification of a panel of mitotic spindle-related genes as a signature predicting survival in lung adenocarcinoma.J Cell Physiol. 2020 May;235(5):4361-4375. doi: 10.1002/jcp.29312. Epub 2019 Oct 21.
631 APPBP2 enhances non-small cell lung cancer proliferation and invasiveness through regulating PPM1D and SPOP.EBioMedicine. 2019 Jun;44:138-149. doi: 10.1016/j.ebiom.2019.05.028. Epub 2019 May 16.
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633 Prognostic implication of aquaporin 1 overexpression in resected lung adenocarcinoma.Interact Cardiovasc Thorac Surg. 2017 Dec 1;25(6):856-861. doi: 10.1093/icvts/ivx202.
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635 Rho Guanine Nucleotide Exchange Factor 5 Increases Lung Cancer Cell Tumorigenesis via MMP-2 and Cyclin D1 Upregulation.Mol Cancer Ther. 2015 Jul;14(7):1671-9. doi: 10.1158/1535-7163.MCT-14-0724. Epub 2015 Mar 16.
636 -PIX controls intracellular viscoelasticity to regulate lung cancer cell migration.J Cell Mol Med. 2015 May;19(5):934-47. doi: 10.1111/jcmm.12441. Epub 2015 Feb 16.
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638 Parkin-Independent Mitophagy Controls Chemotherapeutic Response in Cancer Cells.Cell Rep. 2017 Sep 19;20(12):2846-2859. doi: 10.1016/j.celrep.2017.08.087.
639 Silencing of ARL14 Gene Induces Lung Adenocarcinoma Cells to a Dormant State.Front Cell Dev Biol. 2019 Oct 15;7:238. doi: 10.3389/fcell.2019.00238. eCollection 2019.
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651 BOK displays cell death-independent tumor suppressor activity in non-small-cell lung carcinoma.Int J Cancer. 2017 Nov 15;141(10):2050-2061. doi: 10.1002/ijc.30906. Epub 2017 Aug 7.
652 The biological effect of the nitroimidazole derivative of a polypyridyl ruthenium complex on cancer and endothelial cells.Metallomics. 2015 Mar;7(3):553-66. doi: 10.1039/c5mt00037h.
653 Overexpression of BZW1 is an independent poor prognosis marker and its down-regulation suppresses lung adenocarcinoma metastasis.Sci Rep. 2019 Oct 10;9(1):14624. doi: 10.1038/s41598-019-50874-x.
654 Up-regulation of C5orf34 promotes lung adenocarcinoma migration and is correlated with worse prognosis.Gene. 2019 May 15;696:47-53. doi: 10.1016/j.gene.2019.02.019. Epub 2019 Feb 13.
655 Selective secretion of microRNAs from lung cancer cells via extracellular vesicles promotes CAMK1D-mediated tube formation in endothelial cells.Oncotarget. 2017 Aug 7;8(48):83913-83924. doi: 10.18632/oncotarget.19996. eCollection 2017 Oct 13.
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657 The detectability of the pretreatment EGFR T790M mutations in lung adenocarcinoma using CAST-PCR and digital PCR.J Thorac Dis. 2017 Aug;9(8):2397-2403. doi: 10.21037/jtd.2017.07.02.
658 CASTOR1 suppresses the progression of lung adenocarcinoma and predicts poor prognosis.J Cell Biochem. 2018 Dec;119(12):10186-10194. doi: 10.1002/jcb.27360. Epub 2018 Aug 21.
659 A systematic analysis reveals gene expression alteration of serum deprivation response (SDPR) gene is significantly associated with the survival of patients with cancer.Oncol Rep. 2019 Sep;42(3):1161-1172. doi: 10.3892/or.2019.7212. Epub 2019 Jun 26.
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662 Identification of a lung adenocarcinoma cell line with CCDC6-RET fusion gene and the effect of RET inhibitors in vitro and in vivo.Cancer Sci. 2013 Jul;104(7):896-903. doi: 10.1111/cas.12175. Epub 2013 May 12.
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665 The Atypical Receptor CCRL2 Is Essential for Lung Cancer Immune Surveillance.Cancer Immunol Res. 2019 Nov;7(11):1775-1788. doi: 10.1158/2326-6066.CIR-19-0168. Epub 2019 Sep 4.
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670 CDCA7 promotes lung adenocarcinoma proliferation via regulating the cell cycle.Pathol Res Pract. 2019 Nov;215(11):152559. doi: 10.1016/j.prp.2019.152559. Epub 2019 Aug 1.
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672 The strong propensity of Cadherin-23 for aggregation inhibits cell migration.Mol Oncol. 2019 May;13(5):1092-1109. doi: 10.1002/1878-0261.12469. Epub 2019 Mar 19.
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674 Nullifying the CDKN2AB locus promotes mutant K-ras lung tumorigenesis.Mol Cancer Res. 2014 Jun;12(6):912-23. doi: 10.1158/1541-7786.MCR-13-0620-T. Epub 2014 Mar 11.
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676 Vitamin D Supplementation and Survival of Patients with Non-small Cell Lung Cancer: A Randomized, Double-Blind, Placebo-Controlled Trial.Clin Cancer Res. 2018 Sep 1;24(17):4089-4097. doi: 10.1158/1078-0432.CCR-18-0483. Epub 2018 Jul 17.
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680 CFHR1 is a potentially downregulated gene in lung adenocarcinoma.Mol Med Rep. 2019 Oct;20(4):3642-3648. doi: 10.3892/mmr.2019.10644. Epub 2019 Sep 3.
681 Overexpression of CHD1L is positively associated with metastasis of lung adenocarcinoma and predicts patients poor survival.Oncotarget. 2015 Oct 13;6(31):31181-90. doi: 10.18632/oncotarget.5070.
682 Protein expression of close homologue of L1 (CHL1) is a marker for overall survival in non-small cell lung cancer (NSCLC).J Cancer Res Clin Oncol. 2019 Sep;145(9):2285-2292. doi: 10.1007/s00432-019-02989-x. Epub 2019 Aug 1.
683 CHRNA3 polymorphism modifies lung adenocarcinoma risk in the Chinese Han population.Int J Mol Sci. 2014 Mar 28;15(4):5446-57. doi: 10.3390/ijms15045446.
684 Up-regulation of CKAP2L expression promotes lung adenocarcinoma invasion and is associated with poor prognosis.Onco Targets Ther. 2019 Feb 12;12:1171-1180. doi: 10.2147/OTT.S182242. eCollection 2019.
685 Decrease in paracellular permeability and chemosensitivity to doxorubicin by claudin-1 in spheroid culture models of human lung adenocarcinoma A549 cells.Biochim Biophys Acta Mol Cell Res. 2018 May;1865(5):769-780. doi: 10.1016/j.bbamcr.2018.03.001. Epub 2018 Mar 7.
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687 Identification and association study with lung cancer for novel insertion polymorphisms of human endogenous retrovirus.Carcinogenesis. 2013 Nov;34(11):2531-8. doi: 10.1093/carcin/bgt253. Epub 2013 Jul 19.
688 Methylation of CLEC14A is associated with its expression and lung adenocarcinoma progression.J Cell Physiol. 2019 Mar;234(3):2954-2962. doi: 10.1002/jcp.27112. Epub 2018 Sep 7.
689 Calsyntenin-1, clusterin and neutrophil gelatinase-associated lipocalin are candidate serological biomarkers for lung adenocarcinoma.Oncotarget. 2017 Nov 14;8(64):107964-107976. doi: 10.18632/oncotarget.22438. eCollection 2017 Dec 8.
690 COL5A1 may contribute the metastasis of lung adenocarcinoma.Gene. 2018 Jul 30;665:57-66. doi: 10.1016/j.gene.2018.04.066. Epub 2018 Apr 24.
691 COPB2 promotes cell proliferation and tumorigenesis through up-regulating YAP1 expression in lung adenocarcinoma cells.Biomed Pharmacother. 2018 Jul;103:373-380. doi: 10.1016/j.biopha.2018.04.006. Epub 2018 Apr 24.
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693 Interleukin-1 provided by KIT-competent mast cells is required for KRAS-mutant lung adenocarcinoma.Oncoimmunology. 2019 Apr 11;8(7):1593802. doi: 10.1080/2162402X.2019.1593802. eCollection 2019.
694 Genome-wide unmasking of epigenetically silenced genes in lung adenocarcinoma from smokers and never smokers.Carcinogenesis. 2014 Jun;35(6):1248-57. doi: 10.1093/carcin/bgt494. Epub 2014 Jan 7.
695 CPSF3 is a promising prognostic biomarker and predicts recurrence of non-small cell lung cancer.Oncol Lett. 2019 Sep;18(3):2835-2844. doi: 10.3892/ol.2019.10659. Epub 2019 Jul 24.
696 Expression and potential mechanism of metabolism-related genes and CRLS1 in non-small cell lung cancer.Oncol Lett. 2018 Feb;15(2):2661-2668. doi: 10.3892/ol.2017.7591. Epub 2017 Dec 12.
697 Post-Surgery Circulating Tumor Cells and AXL Overexpression as New Poor Prognostic Biomarkers in Resected Lung Adenocarcinoma.Cancers (Basel). 2019 Nov 7;11(11):1750. doi: 10.3390/cancers11111750.
698 High CTHRC1 expression may be closely associated with angiogenesis and indicates poor prognosis in lung adenocarcinoma patients.Cancer Cell Int. 2019 Nov 29;19:318. doi: 10.1186/s12935-019-1041-5. eCollection 2019.
699 Targeting the Wnt-Regulatory Protein CTNNBIP1 by microRNA-214 Enhances the Stemness and Self-Renewal of Cancer Stem-Like Cells in Lung Adenocarcinomas.Stem Cells. 2015 Dec;33(12):3423-36. doi: 10.1002/stem.2188. Epub 2015 Sep 26.
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703 CUEDC2 down-regulation is associated with tumor growth and poor prognosis in lung adenocarcinoma.Oncotarget. 2015 Aug 21;6(24):20685-96. doi: 10.18632/oncotarget.3930.
704 NCBP1 promotes the development of lung adenocarcinoma through up-regulation of CUL4B.J Cell Mol Med. 2019 Oct;23(10):6965-6977. doi: 10.1111/jcmm.14581. Epub 2019 Aug 26.
705 Mechanism of lung adenocarcinoma spine metastasis induced by CXCL17.Cell Oncol (Dordr). 2020 Apr;43(2):311-320. doi: 10.1007/s13402-019-00491-7. Epub 2019 Dec 12.
706 Cytoglobin has bimodal: tumour suppressor and oncogene functions in lung cancer cell lines.Hum Mol Genet. 2013 Aug 15;22(16):3207-17. doi: 10.1093/hmg/ddt174. Epub 2013 Apr 15.
707 Design of Block Copolymer Micellar Aggregates for Co-Delivery of Enzyme and Anticancer Prodrug.Chem Asian J. 2017 Jan 17;12(2):176-180. doi: 10.1002/asia.201601198. Epub 2016 Dec 14.
708 miR-134-5p Promotes Stage I Lung Adenocarcinoma Metastasis and Chemoresistance by Targeting DAB2.Mol Ther Nucleic Acids. 2019 Dec 6;18:627-637. doi: 10.1016/j.omtn.2019.09.025. Epub 2019 Oct 3.
709 5-Aza-CdR can reverse gefitinib resistance caused by DAPK gene promoter methylation in lung adenocarcinoma cells.Int J Clin Exp Pathol. 2015 Oct 1;8(10):12961-6. eCollection 2015.
710 Selective Cu(I) complex with phosphine-peptide (SarGly) conjugate contra breast cancer: Synthesis, spectroscopic characterization and insight into cytotoxic action.J Inorg Biochem. 2018 Sep;186:162-175. doi: 10.1016/j.jinorgbio.2018.06.009. Epub 2018 Jun 18.
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712 Long Noncoding RNA LINC00472 Inhibits Proliferation and Promotes Apoptosis of Lung Adenocarcinoma Cells via Regulating miR-24-3p/ DEDD.Technol Cancer Res Treat. 2018 Jan 1;17:1533033818790490. doi: 10.1177/1533033818790490.
713 The mitochondrial deoxyguanosine kinase is required for cancer cell stemness in lung adenocarcinoma.EMBO Mol Med. 2019 Dec;11(12):e10849. doi: 10.15252/emmm.201910849. Epub 2019 Oct 21.
714 DHX9 inhibits epithelial-mesenchymal transition in human lung adenocarcinoma cells by regulating STAT3.Am J Transl Res. 2019 Aug 15;11(8):4881-4894. eCollection 2019.
715 DIAPH3 promotes the tumorigenesis of lung adenocarcinoma.Exp Cell Res. 2019 Dec 1;385(1):111662. doi: 10.1016/j.yexcr.2019.111662. Epub 2019 Oct 3.
716 DKK4-knockdown enhances chemosensitivity of A549/DTX cells to docetaxel.Acta Biochim Biophys Sin (Shanghai). 2017 Oct 1;49(10):899-906. doi: 10.1093/abbs/gmx086.
717 DLC1 is the principal biologically-relevant down-regulated DLC family member in several cancers.Oncotarget. 2016 Jul 19;7(29):45144-45157. doi: 10.18632/oncotarget.9266.
718 DMBX1 promotes tumor proliferation and regulates cell cycle progression via repressing OTX2-mediated transcription of p21 in lung adenocarcinoma cell.Cancer Lett. 2019 Jul 1;453:45-56. doi: 10.1016/j.canlet.2019.03.045. Epub 2019 Mar 27.
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725 Development of a reactive stroma associated with prostatic intraepithelial neoplasia in EAF2 deficient mice.PLoS One. 2013 Nov 18;8(11):e79542. doi: 10.1371/journal.pone.0079542. eCollection 2013.
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730 Epithelial tumor suppressor ELF3 is a lineage-specific amplified oncogene in lung adenocarcinoma.Nat Commun. 2019 Nov 28;10(1):5438. doi: 10.1038/s41467-019-13295-y.
731 ELK1-induced upregulation of lncRNA HOXA10-AS promotes lung adenocarcinoma progression by increasing Wnt/-catenin signaling.Biochem Biophys Res Commun. 2018 Jun 27;501(3):612-618. doi: 10.1016/j.bbrc.2018.04.224.
732 Image analysis of the nuclear characteristics of emerin protein and the correlation with nuclear grooves and intranuclear cytoplasmic inclusions in lung adenocarcinoma.Oncol Rep. 2019 Jan;41(1):133-142. doi: 10.3892/or.2018.6848. Epub 2018 Nov 2.
733 ENKUR acts as a tumor suppressor in lung adenocarcinoma cells through PI3K/Akt and MAPK/ERK signaling pathways.J Cancer. 2019 Jul 5;10(17):3975-3984. doi: 10.7150/jca.30021. eCollection 2019.
734 Differential expression and functions of Ehm2 transcript variants in lung adenocarcinoma.Int J Oncol. 2019 May;54(5):1747-1758. doi: 10.3892/ijo.2019.4732. Epub 2019 Feb 27.
735 Integrative PDGF/PDGFR and focal adhesion pathways are downregulated in ERCC1-defective non-small cell lung cancer undergoing sodium glycididazole-sensitized cisplatin treatment.Gene. 2019 Apr 5;691:70-76. doi: 10.1016/j.gene.2018.12.028. Epub 2018 Dec 22.
736 Genetic predisposition to lung adenocarcinoma among never-smoking Chinese with different epidermal growth factor receptor mutation status.Lung Cancer. 2017 Dec;114:79-89. doi: 10.1016/j.lungcan.2017.10.012. Epub 2017 Oct 31.
737 Suppression subtractive hybridization identified differentially expressed genes in lung adenocarcinoma: ERGIC3 as a novel lung cancer-related gene.BMC Cancer. 2013 Feb 1;13:44. doi: 10.1186/1471-2407-13-44.
738 Meta-analysis of mRNA expression profiles to identify differentially expressed genes in lung adenocarcinoma tissue from smokers and non-smokers.Oncol Rep. 2018 Mar;39(3):929-938. doi: 10.3892/or.2018.6197. Epub 2018 Jan 8.
739 Systematic identification of cancer-related long noncoding RNAs and aberrant alternative splicing of quintuple-negative lung adenocarcinoma through RNA-Seq.Lung Cancer. 2017 Jul;109:21-27. doi: 10.1016/j.lungcan.2017.04.009. Epub 2017 Apr 21.
740 DNA methylation profiling identifies the HOXA11 gene as an early diagnostic and prognostic molecular marker in human lung adenocarcinoma.Oncotarget. 2017 May 16;8(20):33100-33109. doi: 10.18632/oncotarget.16528.
741 High FA2H and UGT8 transcript levels predict hydroxylated hexosylceramide accumulation in lung adenocarcinoma.J Lipid Res. 2019 Oct;60(10):1776-1786. doi: 10.1194/jlr.M093955. Epub 2019 Aug 13.
742 LFG-500, a novel synthetic flavonoid, suppresses epithelial-mesenchymal transition in human lung adenocarcinoma cells by inhibiting NLRP3 in inflammatory microenvironment.Cancer Lett. 2017 Aug 1;400:137-148. doi: 10.1016/j.canlet.2017.04.035. Epub 2017 Apr 29.
743 FAM111B, a direct target of p53, promotes the malignant process of lung adenocarcinoma.Onco Targets Ther. 2019 Apr 17;12:2829-2842. doi: 10.2147/OTT.S190934. eCollection 2019.
744 A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population.Nat Genet. 2012 Jul 15;44(8):900-3. doi: 10.1038/ng.2353.
745 Fibulin-2 is a driver of malignant progression in lung adenocarcinoma.PLoS One. 2013 Jun 10;8(6):e67054. doi: 10.1371/journal.pone.0067054. Print 2013.
746 Identification of transcription factors that may reprogram lung adenocarcinoma.Artif Intell Med. 2017 Nov;83:52-57. doi: 10.1016/j.artmed.2017.03.010. Epub 2017 Apr 1.
747 FBXO22 mediates polyubiquitination and inactivation of LKB1 to promote lung cancer cell growth.Cell Death Dis. 2019 Jun 19;10(7):486. doi: 10.1038/s41419-019-1732-9.
748 Multiplex Diagnosis of Oncogenic Fusion and MET Exon Skipping by Molecular Counting Using Formalin-Fixed Paraffin Embedded Lung Adenocarcinoma Tissues.J Thorac Oncol. 2016 Feb;11(2):203-12. doi: 10.1016/j.jtho.2015.10.005. Epub 2015 Dec 19.
749 Role of the focal adhesion protein kindlin-1 in breast cancer growth and lung metastasis.J Natl Cancer Inst. 2011 Sep 7;103(17):1323-37. doi: 10.1093/jnci/djr290. Epub 2011 Aug 10.
750 Kindlin-2 links mechano-environment to proline synthesis and tumor growth.Nat Commun. 2019 Feb 19;10(1):845. doi: 10.1038/s41467-019-08772-3.
751 FGA isoform as an indicator of targeted therapy for EGFR mutated lung adenocarcinoma.J Mol Med (Berl). 2019 Dec;97(12):1657-1668. doi: 10.1007/s00109-019-01848-z. Epub 2019 Nov 28.
752 Integrated Analysis of Transcriptome and Prognosis Data Identifies FGF22 as a Prognostic Marker of Lung Adenocarcinoma.Technol Cancer Res Treat. 2019 Jan 1;18:1533033819827317. doi: 10.1177/1533033819827317.
753 Effect of FGF/FGFR pathway blocking on lung adenocarcinoma and its cancer-associated fibroblasts.J Pathol. 2019 Oct;249(2):193-205. doi: 10.1002/path.5290. Epub 2019 Jun 24.
754 Loss of FGL1 induces epithelialmesenchymal transition and angiogenesis in LKB1 mutant lung adenocarcinoma.Int J Oncol. 2019 Sep;55(3):697-707. doi: 10.3892/ijo.2019.4838. Epub 2019 Jul 15.
755 Overexpression of fibronectin type III domain containing 3B is correlated with epithelial-mesenchymal transition and predicts poor prognosis in lung adenocarcinoma.Exp Ther Med. 2019 May;17(5):3317-3326. doi: 10.3892/etm.2019.7370. Epub 2019 Mar 12.
756 LINC00261 Is an Epigenetically Regulated Tumor Suppressor Essential for Activation of the DNA Damage Response.Cancer Res. 2019 Jun 15;79(12):3050-3062. doi: 10.1158/0008-5472.CAN-18-2034. Epub 2019 Feb 22.
757 Tumor suppression function of FoxD3 in lung cancer.Ir J Med Sci. 2016 Aug;185(3):547-553. doi: 10.1007/s11845-015-1297-2. Epub 2015 Apr 17.
758 Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma.Nat Commun. 2016 Aug 9;7:12451. doi: 10.1038/ncomms12451.
759 Clinical value of microRNA-198-5p downregulation in lung adenocarcinoma and its potential pathways.Oncol Lett. 2019 Sep;18(3):2939-2954. doi: 10.3892/ol.2019.10610. Epub 2019 Jul 12.
760 Fucosyltransferase 2 induced epithelial-mesenchymal transition via TGF-/Smad signaling pathway in lung adenocarcinaoma.Exp Cell Res. 2018 Sep 15;370(2):613-622. doi: 10.1016/j.yexcr.2018.07.026. Epub 2018 Jul 18.
761 Clinicopathological, microenvironmental and genetic determinants of molecular subtypes in KEAP1/NRF2-mutant lung cancer.Int J Cancer. 2019 Feb 15;144(4):788-801. doi: 10.1002/ijc.31975. Epub 2018 Dec 4.
762 GalNAc-T14 promotes metastasis through Wnt dependent HOXB9 expression in lung adenocarcinoma.Oncotarget. 2015 Dec 8;6(39):41916-28. doi: 10.18632/oncotarget.6019.
763 Epithelial-mesenchymal transition markers screened in a cell-based model and validated in lung adenocarcinoma.BMC Cancer. 2019 Jul 11;19(1):680. doi: 10.1186/s12885-019-5885-9.
764 Lung adenocarcinoma-intrinsic GBE1 signaling inhibits anti-tumor immunity.Mol Cancer. 2019 Jun 20;18(1):108. doi: 10.1186/s12943-019-1027-x.
765 GBX2, as a tumor promoter in lung adenocarcinoma, enhances cells viability, invasion and migration by regulating the AKT/ERK signaling pathway.J Gene Med. 2020 Feb;22(2):e3147. doi: 10.1002/jgm.3147. Epub 2019 Dec 20.
766 GCC2-ALK as a targetable fusion in lung adenocarcinoma and its enduring clinical responses to ALK inhibitors.Lung Cancer. 2018 Jan;115:5-11. doi: 10.1016/j.lungcan.2017.10.011. Epub 2017 Oct 27.
767 Integrative Genomic Analyses Identifies GGA2 as a Cooperative Driver of EGFR-Mediated Lung Tumorigenesis.J Thorac Oncol. 2019 Apr;14(4):656-671. doi: 10.1016/j.jtho.2018.12.004. Epub 2018 Dec 19.
768 LSH interacts with and stabilizes GINS4 transcript that promotes tumourigenesis in non-small cell lung cancer.J Exp Clin Cancer Res. 2019 Jun 28;38(1):280. doi: 10.1186/s13046-019-1276-y.
769 Glycerol kinase 5 confers gefitinib resistance through SREBP1/SCD1 signaling pathway.J Exp Clin Cancer Res. 2019 Feb 21;38(1):96. doi: 10.1186/s13046-019-1057-7.
770 Variations of chromosome 2 gene expressions among patients with lung cancer or non-cancer.Cell Biol Toxicol. 2016 Oct;32(5):419-35. doi: 10.1007/s10565-016-9343-z. Epub 2016 Jun 15.
771 Identification of KIF5B-RET and GOPC-ROS1 fusions in lung adenocarcinomas through a comprehensive mRNA-based screen for tyrosine kinase fusions.Clin Cancer Res. 2012 Dec 15;18(24):6599-608. doi: 10.1158/1078-0432.CCR-12-0838. Epub 2012 Oct 10.
772 DNA hypomethylation-related overexpression of SFN, GORASP2 and ZYG11A is a novel prognostic biomarker for early stage lung adenocarcinoma.Oncotarget. 2019 Feb 26;10(17):1625-1636. doi: 10.18632/oncotarget.26676. eCollection 2019 Feb 26.
773 miR-297 acts as an oncogene by targeting GPC5 in lung adenocarcinoma.Cell Prolif. 2016 Oct;49(5):636-43. doi: 10.1111/cpr.12288. Epub 2016 Aug 24.
774 Gephyrin suppresses lung squamous cell carcinoma development by reducing mTOR pathway activation.Cancer Manag Res. 2019 Jun 7;11:5333-5341. doi: 10.2147/CMAR.S204358. eCollection 2019.
775 Up-regulation of long non-coding RNA SPRY4-IT1 promotes tumor cell migration and invasion in lung adenocarcinoma.Oncotarget. 2017 Apr 7;8(31):51058-51065. doi: 10.18632/oncotarget.16918. eCollection 2017 Aug 1.
776 Development of Kras mutant lung adenocarcinoma in mice with knockout of the airway lineage-specific gene Gprc5a.Int J Cancer. 2017 Oct 15;141(8):1589-1599. doi: 10.1002/ijc.30851. Epub 2017 Jul 17.
777 Solution structure and functional investigation of human guanylate kinase reveals allosteric networking and a crucial role for the enzyme in cancer.J Biol Chem. 2019 Aug 2;294(31):11920-11933. doi: 10.1074/jbc.RA119.009251. Epub 2019 Jun 14.
778 Methylation of PRDM2, PRDM5 and PRDM16 genes in lung cancer cells.Int J Clin Exp Pathol. 2014 Apr 15;7(5):2305-11. eCollection 2014.
779 HCP5 is a SMAD3-responsive long non-coding RNA that promotes lung adenocarcinoma metastasis via miR-203/SNAI axis.Theranostics. 2019 Apr 13;9(9):2460-2474. doi: 10.7150/thno.31097. eCollection 2019.
780 Huntingtin-Interacting Protein-1 Is an Early-Stage Prognostic Biomarker of Lung Adenocarcinoma and Suppresses Metastasis via Akt-mediated Epithelial-Mesenchymal Transition.Am J Respir Crit Care Med. 2016 Apr 15;193(8):869-80. doi: 10.1164/rccm.201412-2226OC.
781 A novel in silico reverse-transcriptomics-based identification and blood-based validation of a panel of sub-type specific biomarkers in lung cancer.BMC Genomics. 2013;14 Suppl 6(Suppl 6):S5. doi: 10.1186/1471-2164-14-S6-S5. Epub 2013 Oct 25.
782 YAP mediates the positive regulation of hnRNPK on the lung adenocarcinoma H1299 cell growth.Acta Biochim Biophys Sin (Shanghai). 2019 Jul 10;51(7):677-687. doi: 10.1093/abbs/gmz053.
783 HOPX is methylated and exerts tumour-suppressive function through Ras-induced senescence in human lung cancer.J Pathol. 2015 Feb;235(3):397-407. doi: 10.1002/path.4469. Epub 2014 Dec 18.
784 HORMAD1 Is a Negative Prognostic Indicator in Lung Adenocarcinoma and Specifies Resistance to Oxidative and Genotoxic Stress.Cancer Res. 2018 Nov 1;78(21):6196-6208. doi: 10.1158/0008-5472.CAN-18-1377. Epub 2018 Sep 5.
785 Long noncoding RNA LINC00483/microRNA-144 regulates radiosensitivity and epithelial-mesenchymal transition in lung adenocarcinoma by interacting with HOXA10.J Cell Physiol. 2019 Jul;234(7):11805-11821. doi: 10.1002/jcp.27886. Epub 2019 Feb 4.
786 Downregulation of HOXA3 in lung adenocarcinoma and its relevant molecular mechanism analysed by RT-qPCR, TCGA and in silico analysis.Int J Oncol. 2018 Oct;53(4):1557-1579. doi: 10.3892/ijo.2018.4508. Epub 2018 Jul 30.
787 HOXB2, an adverse prognostic indicator for stage I lung adenocarcinomas, promotes invasion by transcriptional regulation of metastasis-related genes in HOP-62 non-small cell lung cancer cells.Anticancer Res. 2008 Jul-Aug;28(4B):2121-7.
788 HOXB7 overexpression in lung cancer is a hallmark of acquired stem-like phenotype.Oncogene. 2018 Jun;37(26):3575-3588. doi: 10.1038/s41388-018-0229-9. Epub 2018 Mar 26.
789 HOXC13 promotes proliferation of lung adenocarcinoma via modulation of CCND1 and CCNE1.Am J Cancer Res. 2017 Sep 1;7(9):1820-1834. eCollection 2017.
790 Regulation of miRNA Biogenesis and Histone Modification by K63-Polyubiquitinated DDX17 Controls Cancer Stem-like Features.Cancer Res. 2019 May 15;79(10):2549-2563. doi: 10.1158/0008-5472.CAN-18-2376. Epub 2019 Mar 15.
791 Transcription deregulation at the 15q25 locus in association with lung adenocarcinoma risk.Clin Cancer Res. 2009 Mar 1;15(5):1837-42. doi: 10.1158/1078-0432.CCR-08-2107. Epub 2009 Feb 17.
792 Inhibitor of DNA-Binding Protein 4 Suppresses Cancer Metastasis through the Regulation of Epithelial Mesenchymal Transition in Lung Adenocarcinoma.Cancers (Basel). 2019 Dec 14;11(12):2021. doi: 10.3390/cancers11122021.
793 Effect of IDH3a on glucose uptake in lung adenocarcinoma: A pilot study based on [(18) F]FDG.Cancer Med. 2019 Sep;8(11):5341-5351. doi: 10.1002/cam4.2421. Epub 2019 Jul 29.
794 Decreased IFIT2 Expression In Human Non-Small-Cell Lung Cancer Tissues Is Associated With Cancer Progression And Poor Survival Of The Patients.Onco Targets Ther. 2019 Oct 3;12:8139-8149. doi: 10.2147/OTT.S220698. eCollection 2019.
795 Prognostic significance of IFITM1 expression and correlation with microvessel density and epithelial-mesenchymal transition signature in lung adenocarcinoma.Pathol Res Pract. 2019 Jul;215(7):152444. doi: 10.1016/j.prp.2019.152444. Epub 2019 May 6.
796 Interferon induced transmembrane protein 3 regulates the growth and invasion of human lung adenocarcinoma.Thorac Cancer. 2017 Jul;8(4):337-343. doi: 10.1111/1759-7714.12451. Epub 2017 May 23.
797 VICKZ1 enhances tumor progression and metastasis in lung adenocarcinomas in mice.Oncogene. 2019 May;38(21):4169-4181. doi: 10.1038/s41388-019-0715-8. Epub 2019 Jan 30.
798 Expression profile, clinical significance, and biological function of insulin-like growth factor 2 messenger RNA-binding proteins in non-small cell lung cancer.Tumour Biol. 2017 Apr;39(4):1010428317695928. doi: 10.1177/1010428317695928.
799 Clinical implications of the novel cytokine IL-38 expressed in lung adenocarcinoma: Possible association with PD-L1 expression.PLoS One. 2017 Jul 20;12(7):e0181598. doi: 10.1371/journal.pone.0181598. eCollection 2017.
800 Prognostic significance of IMMT expression in surgically-resected lung adenocarcinoma.Thorac Cancer. 2019 Nov;10(11):2142-2151. doi: 10.1111/1759-7714.13200. Epub 2019 Oct 3.
801 Role of INSL4 Signaling in Sustaining the Growth and Viability of LKB1-Inactivated Lung Cancer.J Natl Cancer Inst. 2019 Jul 1;111(7):664-674. doi: 10.1093/jnci/djy166.
802 Effect of FAM196B in human lung adenocarcinoma.J Cancer. 2018 Jun 14;9(14):2451-2459. doi: 10.7150/jca.24907. eCollection 2018.
803 Engagement of overexpressed Her2 with GEP100 induces autonomous invasive activities and provides a biomarker for metastases of lung adenocarcinoma.PLoS One. 2011;6(9):e25301. doi: 10.1371/journal.pone.0025301. Epub 2011 Sep 22.
804 Interferon regulatory factor 4 (IRF4) is overexpressed in human nonsmall cell lung cancer (NSCLC) and activates the Notch signaling pathway.Mol Med Rep. 2017 Nov;16(5):6034-6040. doi: 10.3892/mmr.2017.7319. Epub 2017 Aug 22.
805 Genome-wide identification of transcription factors that are critical to non-small cell lung cancer.Cancer Lett. 2018 Oct 10;434:132-143. doi: 10.1016/j.canlet.2018.07.020. Epub 2018 Jul 18.
806 Cationic liposome-mediated nitric oxide synthase gene therapy enhances the antitumor effects of cisplatin in lung cancer.Int J Mol Med. 2013 Jan;31(1):33-42. doi: 10.3892/ijmm.2012.1171. Epub 2012 Nov 1.
807 Low expression of ITIH5 in adenocarcinoma of the lung is associated with unfavorable patients' outcome.Epigenetics. 2015;10(10):903-12. doi: 10.1080/15592294.2015.1078049. Epub 2015 Aug 7.
808 Inositol-1,4,5-trisphosphate 3-kinase-A (ITPKA) is frequently over-expressed and functions as an oncogene in several tumor types.Biochem Pharmacol. 2017 Aug 1;137:1-9. doi: 10.1016/j.bcp.2017.03.023. Epub 2017 Apr 2.
809 PCAF-mediated acetylation of transcriptional factor HOXB9 suppresses lung adenocarcinoma progression by targeting oncogenic protein JMJD6.Nucleic Acids Res. 2016 Dec 15;44(22):10662-10675. doi: 10.1093/nar/gkw808. Epub 2016 Sep 8.
810 Identification of a novel partner gene, KIAA1217, fused to RET: Functional characterization and inhibitor sensitivity of two isoforms in lung adenocarcinoma.Oncotarget. 2016 Jun 14;7(24):36101-36114. doi: 10.18632/oncotarget.9137.
811 ARMS for EGFR mutation analysis of cytologic and corresponding lung adenocarcinoma histologic specimens.J Cancer Res Clin Oncol. 2015 Feb;141(2):221-7. doi: 10.1007/s00432-014-1807-z. Epub 2014 Aug 26.
812 Identification of a novel KIF13A-RET fusion in lung adenocarcinoma by next-generation sequencing.Lung Cancer. 2018 Apr;118:27-29. doi: 10.1016/j.lungcan.2017.08.019. Epub 2017 Sep 4.
813 Therapeutic Targeting of the Premetastatic Stage in Human Lung-to-Brain Metastasis.Cancer Res. 2018 Sep 1;78(17):5124-5134. doi: 10.1158/0008-5472.CAN-18-1022. Epub 2018 Jul 9.
814 Overexpression of KIF18A promotes cell proliferation, inhibits apoptosis, and independently predicts unfavorable prognosis in lung adenocarcinoma.IUBMB Life. 2019 Jul;71(7):942-955. doi: 10.1002/iub.2030. Epub 2019 Feb 28.
815 Overexpression of KIF20A confers malignant phenotype of lung adenocarcinoma by promoting cell proliferation and inhibiting apoptosis.Cancer Med. 2018 Sep;7(9):4678-4689. doi: 10.1002/cam4.1710. Epub 2018 Aug 13.
816 High KIF2A expression promotes proliferation, migration and predicts poor prognosis in lung adenocarcinoma.Biochem Biophys Res Commun. 2018 Feb 26;497(1):65-72. doi: 10.1016/j.bbrc.2018.02.020. Epub 2018 Feb 7.
817 Co-expression network analysis identified KIF2C in association with progression and prognosis in lung adenocarcinoma.Cancer Biomark. 2019;24(3):371-382. doi: 10.3233/CBM-181512.
818 Krppel-like Transcription Factor KLF10 Suppresses TGF-Induced Epithelial-to-Mesenchymal Transition via a Negative Feedback Mechanism.Cancer Res. 2017 May 1;77(9):2387-2400. doi: 10.1158/0008-5472.CAN-16-2589. Epub 2017 Mar 1.
819 High KRT8 Expression Independently Predicts Poor Prognosis for Lung Adenocarcinoma Patients.Genes (Basel). 2019 Jan 10;10(1):36. doi: 10.3390/genes10010036.
820 A Diagnostic Panel of DNA Methylation Biomarkers for Lung Adenocarcinoma.Front Oncol. 2019 Dec 3;9:1281. doi: 10.3389/fonc.2019.01281. eCollection 2019.
821 Long Non-coding RNA LINC00628 Interacts Epigenetically with the LAMA3 Promoter and Contributes to Lung Adenocarcinoma.Mol Ther Nucleic Acids. 2019 Dec 6;18:166-182. doi: 10.1016/j.omtn.2019.08.005. Epub 2019 Aug 14.
822 Novel STAT3 Inhibitor LDOC1 Targets Phospho-JAK2 for Degradation by Interacting with LNX1 and Regulates the Aggressiveness of Lung Cancer.Cancers (Basel). 2019 Jan 9;11(1):63. doi: 10.3390/cancers11010063.
823 Inverse correlation between galectin-4 and TTF-1 in lung adenocarcinoma.Virchows Arch. 2017 Sep;471(3):375-382. doi: 10.1007/s00428-017-2202-3. Epub 2017 Jul 19.
824 miR-17-92/p38 Dysregulation Enhances Wnt Signaling and Selects Lgr6+ Cancer Stem-like Cells during Lung Adenocarcinoma Progression.Cancer Res. 2016 Jul 1;76(13):4012-22. doi: 10.1158/0008-5472.CAN-15-3302. Epub 2016 May 4.
825 LHX3 is an early stage and radiosensitivity prognostic biomarker in lung adenocarcinoma.Oncol Rep. 2017 Sep;38(3):1482-1490. doi: 10.3892/or.2017.5833. Epub 2017 Jul 18.
826 A cancer-testis non-coding RNA LIN28B-AS1 activates driver gene LIN28B by interacting with IGF2BP1 in lung adenocarcinoma.Oncogene. 2019 Mar;38(10):1611-1624. doi: 10.1038/s41388-018-0548-x. Epub 2018 Oct 23.
827 Dual strands of the miR-145 duplex (miR-145-5p and miR-145-3p) regulate oncogenes in lung adenocarcinoma pathogenesis.J Hum Genet. 2018 Oct;63(10):1015-1028. doi: 10.1038/s10038-018-0497-9. Epub 2018 Aug 6.
828 LPCAT1 promotes brain metastasis of lung adenocarcinoma by up-regulating PI3K/AKT/MYC pathway.J Exp Clin Cancer Res. 2019 Feb 21;38(1):95. doi: 10.1186/s13046-019-1092-4.
829 Lipin-1 determines lung cancer cell survival and chemotherapy sensitivity by regulation of endoplasmic reticulum homeostasis and autophagy.Cancer Med. 2018 Jun;7(6):2541-2554. doi: 10.1002/cam4.1483. Epub 2018 Apr 16.
830 Single nucleotide polymorphism in the 3' untranslated region of LPP is a risk factor for lung cancer: a case-control study.BMC Cancer. 2019 Jan 8;19(1):35. doi: 10.1186/s12885-018-5241-5.
831 Epigenomic profiling of non-small cell lung cancer xenografts uncover LRP12 DNA methylation as predictive biomarker for carboplatin resistance.Genome Med. 2018 Jul 20;10(1):55. doi: 10.1186/s13073-018-0562-1.
832 Proteasome-Independent Protein Knockdown by Small-Molecule Inhibitor for the Undruggable Lung Adenocarcinoma.J Am Chem Soc. 2019 Nov 20;141(46):18492-18499. doi: 10.1021/jacs.9b08777. Epub 2019 Nov 11.
833 Prostaglandin E-Major Urinary Metabolite (PGE-MUM) as a Tumor Marker for Lung Adenocarcinoma.Cancers (Basel). 2019 Jun 3;11(6):768. doi: 10.3390/cancers11060768.
834 Water-soluble variant of human Lynx1 induces cell cycle arrest and apoptosis in lung cancer cells via modulation of 7 nicotinic acetylcholine receptors.PLoS One. 2019 May 31;14(5):e0217339. doi: 10.1371/journal.pone.0217339. eCollection 2019.
835 Prognostic and predictive values of CDK1 and MAD2L1 in lung adenocarcinoma.Oncotarget. 2016 Dec 20;7(51):85235-85243. doi: 10.18632/oncotarget.13252.
836 LncRNA MAFG-AS1 boosts the proliferation of lung adenocarcinoma cells via regulating miR-744-5p/MAFG axis.Eur J Pharmacol. 2019 Sep 15;859:172465. doi: 10.1016/j.ejphar.2019.172465. Epub 2019 Jun 15.
837 An activation of LC3A-mediated autophagy contributes to de novo and acquired resistance to EGFR tyrosine kinase inhibitors in lung adenocarcinoma.J Pathol. 2014 Oct;234(2):277-88. doi: 10.1002/path.4354. Epub 2014 Aug 18.
838 Map2k4 functions as a tumor suppressor in lung adenocarcinoma and inhibits tumor cell invasion by decreasing peroxisome proliferator-activated receptor 2 expression.Mol Cell Biol. 2011 Nov;31(21):4270-85. doi: 10.1128/MCB.05562-11. Epub 2011 Sep 6.
839 MAPK4 overexpression promotes tumor progression via noncanonical activation of AKT/mTOR signaling.J Clin Invest. 2019 Mar 1;129(3):1015-1029. doi: 10.1172/JCI97712. Epub 2019 Jan 28.
840 MARCH9 Suppresses Lung Adenocarcinoma Progression by Downregulating ICAM-1.Cell Physiol Biochem. 2018;50(1):92-107. doi: 10.1159/000493961. Epub 2018 Oct 2.
841 Mammalian mediator 19 mediates H1299 lung adenocarcinoma cell clone conformation, growth, and metastasis.Asian Pac J Cancer Prev. 2012;13(8):3695-700. doi: 10.7314/apjcp.2012.13.8.3695.
842 Loss of imprinting of PEG1/MEST in lung cancer cell lines.Oncol Rep. 2004 Dec;12(6):1273-8.
843 The m(6)A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells.Mol Cell. 2016 May 5;62(3):335-345. doi: 10.1016/j.molcel.2016.03.021. Epub 2016 Apr 21.
844 MFF Regulation of Mitochondrial Cell Death Is a Therapeutic Target in Cancer.Cancer Res. 2019 Dec 15;79(24):6215-6226. doi: 10.1158/0008-5472.CAN-19-1982. Epub 2019 Oct 3.
845 MID1-PP2A complex functions as new insights in human lung adenocarcinoma.J Cancer Res Clin Oncol. 2018 May;144(5):855-864. doi: 10.1007/s00432-018-2601-0. Epub 2018 Feb 15.
846 MIIP accelerates epidermal growth factor receptor protein turnover and attenuates proliferation in non-small cell lung cancer.Oncotarget. 2016 Feb 23;7(8):9118-34. doi: 10.18632/oncotarget.7001.
847 Comprehensive Profiling of Gene Copy Number Alterations Predicts Patient Prognosis in Resected Stages I-III Lung Adenocarcinoma.Front Oncol. 2019 Aug 6;9:556. doi: 10.3389/fonc.2019.00556. eCollection 2019.
848 MPC1 deficiency accelerates lung adenocarcinoma progression through the STAT3 pathway.Cell Death Dis. 2019 Feb 15;10(3):148. doi: 10.1038/s41419-019-1324-8.
849 p53-inducible gene 3 promotes cell migration and invasion by activating the FAK/Src pathway in lung adenocarcinoma.Cancer Sci. 2018 Dec;109(12):3783-3793. doi: 10.1111/cas.13818. Epub 2018 Oct 26.
850 Thyroid transcription factor-1-regulated microRNA-532-5p targets KRAS and MKL2 oncogenes and induces apoptosis in lung adenocarcinoma cells.Cancer Sci. 2017 Jul;108(7):1394-1404. doi: 10.1111/cas.13271. Epub 2017 Jun 10.
851 Expression of xeroderma pigmentosum complementation group C protein predicts cisplatin resistance in lung adenocarcinoma patients.Oncol Rep. 2011 May;25(5):1243-51. doi: 10.3892/or.2011.1184. Epub 2011 Feb 14.
852 MTBP promotes migration and invasion by regulation of ZEB2-mediated epithelial-mesenchymal transition in lung cancer cells.Onco Targets Ther. 2018 Oct 10;11:6741-6756. doi: 10.2147/OTT.S167963. eCollection 2018.
853 Prognostic roles of mitochondrial transcription termination factors in non-small cell lung cancer.Oncol Lett. 2019 Oct;18(4):3453-3462. doi: 10.3892/ol.2019.10680. Epub 2019 Jul 29.
854 Metastasis suppressor 1 (MTSS1) expression is associated with reduced in-vivo metastasis and enhanced patient survival in lung adenocarcinoma.Clin Exp Metastasis. 2018 Feb;35(1-2):15-23. doi: 10.1007/s10585-017-9869-3. Epub 2017 Dec 7.
855 Specific expression of MUC21 in micropapillary elements of lung adenocarcinomas - Implications for the progression of EGFR-mutated lung adenocarcinomas.PLoS One. 2019 Apr 11;14(4):e0215237. doi: 10.1371/journal.pone.0215237. eCollection 2019.
856 IL-25 promotes cisplatin resistance of lung cancer cells by activating NF-B signaling pathway to increase of major vault protein.Cancer Med. 2019 Jul;8(7):3491-3501. doi: 10.1002/cam4.2213. Epub 2019 May 1.
857 LncRNA LOXL1-AS1 regulates the tumorigenesis and development of lung adenocarcinoma through sponging miR-423-5p and targeting MYBL2.Cancer Med. 2020 Jan;9(2):689-699. doi: 10.1002/cam4.2641. Epub 2019 Nov 23.
858 Napsin A Expression in Subtypes of Thyroid Tumors: Comparison with Lung Adenocarcinomas.Endocr Pathol. 2020 Mar;31(1):39-45. doi: 10.1007/s12022-019-09600-6.
859 Identification of an eight-gene prognostic signature for lung adenocarcinoma.Cancer Manag Res. 2018 Sep 10;10:3383-3392. doi: 10.2147/CMAR.S173941. eCollection 2018.
860 NCAPG2 promotes tumour proliferation by regulating G2/M phase and associates with poor prognosis in lung adenocarcinoma.J Cell Mol Med. 2017 Apr;21(4):665-676. doi: 10.1111/jcmm.13010. Epub 2016 Nov 15.
861 Evaluation of transcriptionally regulated genes identifies NCOR1 in hormone receptor negative breast tumors and lung adenocarcinomas as a potential tumor suppressor gene.PLoS One. 2018 Nov 28;13(11):e0207776. doi: 10.1371/journal.pone.0207776. eCollection 2018.
862 Dissecting the expression landscape of mitochondrial genes in lung squamous cell carcinoma and lung adenocarcinoma.Oncol Lett. 2018 Sep;16(3):3992-4000. doi: 10.3892/ol.2018.9113. Epub 2018 Jul 10.
863 Nonsense and missense mutation of mitochondrial ND6 gene promotes cell migration and invasion in human lung adenocarcinoma.BMC Cancer. 2015 May 2;15:346. doi: 10.1186/s12885-015-1349-z.
864 Nectin-3 is a new biomarker that mediates the upregulation of MMP2 and MMP9 in ovarian cancer cells.Biomed Pharmacother. 2019 Feb;110:139-144. doi: 10.1016/j.biopha.2018.11.020. Epub 2018 Nov 20.
865 Inhibition of TWIST1 leads to activation of oncogene-induced senescence in oncogene-driven non-small cell lung cancer.Mol Cancer Res. 2013 Apr;11(4):329-38. doi: 10.1158/1541-7786.MCR-12-0456. Epub 2013 Jan 30.
866 NFATc2 enhances tumor-initiating phenotypes through the NFATc2/SOX2/ALDH axis in lung adenocarcinoma.Elife. 2017 Jul 24;6:e26733. doi: 10.7554/eLife.26733.
867 Cellular prion protein transcriptionally regulated by NFIL3 enhances lung cancer cell lamellipodium formation and migration through JNK signaling.Oncogene. 2020 Jan;39(2):385-398. doi: 10.1038/s41388-019-0994-0. Epub 2019 Sep 2.
868 NFIX downregulation independently predicts poor prognosis in lung adenocarcinoma, but not in squamous cell carcinoma.Future Oncol. 2018 Dec;14(30):3135-3144. doi: 10.2217/fon-2018-0164. Epub 2018 Nov 12.
869 NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis.Nature. 2017 Nov 30;551(7682):639-643. doi: 10.1038/nature24637. Epub 2017 Nov 22.
870 MiR-142-3p suppresses the proliferation, migration and invasion through inhibition of NR2F6 in lung adenocarcinoma.Hum Cell. 2019 Oct;32(4):437-446. doi: 10.1007/s13577-019-00258-0. Epub 2019 Jun 5.
871 Identification of Epigenetic Biomarkers of Lung Adenocarcinoma through Multi-Omics Data Analysis.PLoS One. 2016 Apr 4;11(4):e0152918. doi: 10.1371/journal.pone.0152918. eCollection 2016.
872 NUP58 facilitates metastasis and epithelial-mesenchymal transition of lung adenocarcinoma via the GSK-3/Snail signaling pathway.Am J Transl Res. 2019 Jan 15;11(1):393-405. eCollection 2019.
873 Prevalence, clinicopathologic characteristics, and molecular associations of EGFR exon 20 insertion mutations in East Asian patients with lung adenocarcinoma.Ann Surg Oncol. 2014 Dec;21 Suppl 4:S490-6. doi: 10.1245/s10434-013-3452-1. Epub 2014 Jan 14.
874 High expression of ovarian cancer immunoreactive antigen domain containing 2 (OCIAD2) is associated with poor prognosis in lung adenocarcinoma.Pathol Int. 2018 Nov;68(11):596-604. doi: 10.1111/pin.12724. Epub 2018 Oct 15.
875 Increase in resistance to anticancer drugs involves occludin in spheroid culture model of lung adenocarcinoma A549 cells.Sci Rep. 2018 Oct 11;8(1):15157. doi: 10.1038/s41598-018-33566-w.
876 Orai3 constitutes a native store-operated calcium entry that regulates non small cell lung adenocarcinoma cell proliferation.PLoS One. 2013 Sep 13;8(9):e72889. doi: 10.1371/journal.pone.0072889. eCollection 2013.
877 Serum -1 Acid Glycoprotein is a Biomarker for the Prediction of Targeted Therapy Resistance in Advanced EGFR-positive Lung Adenocarcinoma.Comb Chem High Throughput Screen. 2018;21(10):755-759. doi: 10.2174/1386207322666190119163024.
878 The deubiquitylase OTUD3 stabilizes GRP78 and promotes lung tumorigenesis.Nat Commun. 2019 Jul 2;10(1):2914. doi: 10.1038/s41467-019-10824-7.
879 Upregulation of OTUD7B (Cezanne) Promotes Tumor Progression via AKT/VEGF Pathway in Lung Squamous Carcinoma and Adenocarcinoma.Front Oncol. 2019 Sep 11;9:862. doi: 10.3389/fonc.2019.00862. eCollection 2019.
880 Ovol2 gene inhibits the Epithelial-to-Mesenchymal Transition in lung adenocarcinoma by transcriptionally repressing Twist1.Gene. 2017 Feb 5;600:1-8. doi: 10.1016/j.gene.2016.11.034. Epub 2016 Nov 21.
881 High-resolution detection of recurrent aberrations in lung adenocarcinomas by array comparative genomic hybridization and expression analysis of selective genes by quantitative PCR.Int J Oncol. 2014 Jun;44(6):2068-76. doi: 10.3892/ijo.2014.2384. Epub 2014 Apr 11.
882 Overexpression of PAFAH1B1 is associated with tumor metastasis and poor survival in non-small cell lung cancer.Lung Cancer. 2012 Sep;77(3):585-92. doi: 10.1016/j.lungcan.2012.05.105. Epub 2012 Jun 29.
883 Paip1 predicts poor prognosis and promotes tumor progression through AKT/GSK-3 pathway in lung adenocarcinoma.Hum Pathol. 2019 Apr;86:233-242. doi: 10.1016/j.humpath.2018.11.017. Epub 2018 Nov 26.
884 Modulation of Mutant Kras(G12D) -Driven Lung Tumorigenesis In Vivo by Gain or Loss of PCDH7 Function.Mol Cancer Res. 2019 Feb;17(2):594-603. doi: 10.1158/1541-7786.MCR-18-0739. Epub 2018 Nov 8.
885 Absolute quantification of DNA methylation using microfluidic chip-based digital PCR.Biosens Bioelectron. 2017 Oct 15;96:339-344. doi: 10.1016/j.bios.2017.05.021. Epub 2017 May 12.
886 PEST-containing nuclear protein regulates cell proliferation, migration, and invasion in lung adenocarcinoma.Oncogenesis. 2019 Mar 14;8(3):22. doi: 10.1038/s41389-019-0132-4.
887 Expression of programmed cell death 5 protein inhibits progression of lung carcinoma in vitro and in vivo via the mitochondrial apoptotic pathway.Mol Med Rep. 2014 Oct;10(4):2059-64. doi: 10.3892/mmr.2014.2454. Epub 2014 Aug 5.
888 HOXA4-Dependent Transcriptional Activation of AXL Promotes Cisplatin- Resistance in Lung Adenocarcinoma Cells.Anticancer Agents Med Chem. 2018;18(14):2062-2067. doi: 10.2174/1871520619666181203110835.
889 MAP17 predicts sensitivity to platinum-based therapy, EGFR inhibitors and the proteasome inhibitor bortezomib in lung adenocarcinoma.J Exp Clin Cancer Res. 2018 Aug 17;37(1):195. doi: 10.1186/s13046-018-0871-7.
890 miR-15b regulates cisplatin resistance and metastasis by targeting PEBP4 in human lung adenocarcinoma cells.Cancer Gene Ther. 2015 Apr;22(3):108-14. doi: 10.1038/cgt.2014.73. Epub 2015 Feb 27.
891 Pellino-1 promotes lung carcinogenesis via the stabilization of Slug and Snail through K63-mediated polyubiquitination.Cell Death Differ. 2017 Mar;24(3):469-480. doi: 10.1038/cdd.2016.143. Epub 2016 Dec 23.
892 PERP gene therapy attenuates lung cancer xenograft via inducing apoptosis and suppressing VEGF.Cancer Biol Ther. 2011 Dec 15;12(12):1114-9. doi: 10.4161/cbt.12.12.18435. Epub 2011 Dec 15.
893 The effect of piperlongumine on endothelial and lung adenocarcinoma cells with regulated expression of profilin-1.Onco Targets Ther. 2018 Nov 22;11:8275-8292. doi: 10.2147/OTT.S183191. eCollection 2018.
894 PHD finger protein 5A promoted lung adenocarcinoma progression via alternative splicing.Cancer Med. 2019 May;8(5):2429-2441. doi: 10.1002/cam4.2115. Epub 2019 Apr 1.
895 Identification of novel gene expression signature in lung adenocarcinoma by using next-generation sequencing data and bioinformatics analysis.Oncotarget. 2017 Sep 18;8(62):104831-104854. doi: 10.18632/oncotarget.21022. eCollection 2017 Dec 1.
896 High PHLPP1 expression levels predicts longer time of acquired resistance to EGFR tyrosine kinase inhibitors in patients with lung adenocarcinoma.Oncotarget. 2017 Aug 1;8(35):59000-59007. doi: 10.18632/oncotarget.19777. eCollection 2017 Aug 29.
897 Identification of the targets of hematoporphyrin derivative in lung adenocarcinoma using integrated network analysis.Biol Res. 2019 Feb 4;52(1):4. doi: 10.1186/s40659-019-0213-z.
898 TGF- regulates the proliferation of lung adenocarcinoma cells by inhibiting PIK3R3 expression.Mol Carcinog. 2015 Jun;54 Suppl 1:E162-71. doi: 10.1002/mc.22243. Epub 2014 Nov 5.
899 PINK1 Expression Is Associated with Poor Prognosis in Lung Adenocarcinoma.Tohoku J Exp Med. 2018 Jun;245(2):115-121. doi: 10.1620/tjem.245.115.
900 High PITX1 expression in lung adenocarcinoma patients is associated with DNA methylation and poor prognosis.Pathol Res Pract. 2018 Dec;214(12):2046-2053. doi: 10.1016/j.prp.2018.09.025. Epub 2018 Sep 29.
901 PITX2 enhances progression of lung adenocarcinoma by transcriptionally regulating WNT3A and activating Wnt/-catenin signaling pathway.Cancer Cell Int. 2019 Apr 11;19:96. doi: 10.1186/s12935-019-0800-7. eCollection 2019.
902 Cancer-testis gene PIWIL1 promotes cell proliferation, migration, and invasion in lung adenocarcinoma.Cancer Med. 2018 Jan;7(1):157-166. doi: 10.1002/cam4.1248. Epub 2017 Nov 23.
903 High PKD2 predicts poor prognosis in lung adenocarcinoma via promoting Epithelial-mesenchymal Transition.Sci Rep. 2019 Feb 4;9(1):1324. doi: 10.1038/s41598-018-37285-0.
904 Transcription factor PREP1 induces EMT and metastasis by controlling the TGF--SMAD3 pathway in non-small cell lung adenocarcinoma.Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):E3775-84. doi: 10.1073/pnas.1407074111. Epub 2014 Aug 25.
905 Unbiased peptoid combinatorial cell screen identifies plectin protein as a potential biomarker for lung cancer stem cells.Sci Rep. 2019 Oct 18;9(1):14954. doi: 10.1038/s41598-019-51004-3.
906 Drug-resistant CXCR4-positive cells have the molecular characteristics of EMT in NSCLC.Gene. 2016 Dec 5;594(1):23-29. doi: 10.1016/j.gene.2016.08.043. Epub 2016 Aug 28.
907 Adipophilin expression in lung adenocarcinoma is associated with apocrine-like features and poor clinical prognosis: an immunohistochemical study of 328 cases.Histopathology. 2017 Jan;70(2):232-241. doi: 10.1111/his.13048. Epub 2016 Sep 27.
908 Phospholipid Phosphatase 4 promotes proliferation and tumorigenesis, and activates Ca(2+)-permeable Cationic Channel in lung carcinoma cells.Mol Cancer. 2017 Aug 29;16(1):147. doi: 10.1186/s12943-017-0717-5.
909 TMEPAI regulates EMT in lung cancer cells by modulating the ROS and IRS-1 signaling pathways.Carcinogenesis. 2013 Aug;34(8):1764-72. doi: 10.1093/carcin/bgt132. Epub 2013 Apr 24.
910 Knockdown of POLE2 expression suppresses lung adenocarcinoma cell malignant phenotypes invitro.Oncol Rep. 2018 Nov;40(5):2477-2486. doi: 10.3892/or.2018.6659. Epub 2018 Aug 17.
911 Neural lineage-specific homeoprotein BRN2 is directly involved in TTF1 expression in small-cell lung cancer.Lab Invest. 2013 Apr;93(4):408-21. doi: 10.1038/labinvest.2013.2. Epub 2013 Jan 28.
912 Blimp1 activation by AP-1 in human lung cancer cells promotes a migratory phenotype and is inhibited by the lysyl oxidase propeptide.PLoS One. 2012;7(3):e33287. doi: 10.1371/journal.pone.0033287. Epub 2012 Mar 15.
913 PRDM16 functions as a suppressor of lung adenocarcinoma metastasis.J Exp Clin Cancer Res. 2019 Jan 25;38(1):35. doi: 10.1186/s13046-019-1042-1.
914 Genetic polymorphisms in the Rb-binding zinc finger gene RIZ and the risk of lung cancer.Carcinogenesis. 2007 Sep;28(9):1971-7. doi: 10.1093/carcin/bgm156. Epub 2007 Aug 11.
915 Downregulation of peroxiredoxin-1 by -elemene enhances the radiosensitivity of lung adenocarcinoma xenografts.Oncol Rep. 2015 Mar;33(3):1427-33. doi: 10.3892/or.2015.3732. Epub 2015 Jan 19.
916 DACH1 inhibits the proliferation and invasion of lung adenocarcinoma through the downregulation of peroxiredoxin 3.Tumour Biol. 2016 Jul;37(7):9781-8. doi: 10.1007/s13277-016-4811-x. Epub 2016 Jan 25.
917 PRP19 upregulation inhibits cell proliferation in lung adenocarcinomas by p21-mediated induction of cell cycle arrest.Biomed Pharmacother. 2014 May;68(4):463-70. doi: 10.1016/j.biopha.2014.03.006. Epub 2014 Mar 18.
918 Proscillaridin A Promotes Oxidative Stress and ER Stress, Inhibits STAT3 Activation, and Induces Apoptosis in A549 Lung Adenocarcinoma Cells.Oxid Med Cell Longev. 2018 Jan 11;2018:3853409. doi: 10.1155/2018/3853409. eCollection 2018.
919 PSMA7 inhibits the tumorigenicity of A549 human lung adenocarcinoma cells.Mol Cell Biochem. 2012 Jul;366(1-2):131-7. doi: 10.1007/s11010-012-1290-2. Epub 2012 May 15.
920 Direct activation of PP2A for the treatment of tyrosine kinase inhibitor-resistant lung adenocarcinoma.JCI Insight. 2019 Feb 21;4(4):e125693. doi: 10.1172/jci.insight.125693. eCollection 2019 Feb 21.
921 Prognostic implication of PTPRH hypomethylation in non-small cell lung cancer.Oncol Rep. 2015 Sep;34(3):1137-45. doi: 10.3892/or.2015.4082. Epub 2015 Jun 25.
922 Recurrent PTPRT/JAK2 mutations in lung adenocarcinoma among African Americans.Nat Commun. 2019 Dec 16;10(1):5735. doi: 10.1038/s41467-019-13732-y.
923 The anoikis effector Bit1 displays tumor suppressive function in lung cancer cells.PLoS One. 2014 Jul 8;9(7):e101564. doi: 10.1371/journal.pone.0101564. eCollection 2014.
924 Paxillin expression and amplification in early lung lesions of high-risk patients, lung adenocarcinoma and metastatic disease.J Clin Pathol. 2011 Jan;64(1):16-24. doi: 10.1136/jcp.2010.075853. Epub 2010 Nov 2.
925 Rab27b Is a Potential Indicator for Lymph Node Metastasis and Unfavorable Prognosis in Lung Adenocarcinoma.Dis Markers. 2018 Dec 2;2018:7293962. doi: 10.1155/2018/7293962. eCollection 2018.
926 CRKL as a lung cancer oncogene and mediator of acquired resistance to EGFR inhibitors: is it all that it is cracked up to be?.Cancer Discov. 2011 Dec;1(7):560-1. doi: 10.1158/2159-8290.CD-11-0295.
927 Prevalence and clinical significance of RBM3 immunostaining in non-small cell lung cancers.J Cancer Res Clin Oncol. 2019 Apr;145(4):873-879. doi: 10.1007/s00432-019-02850-1. Epub 2019 Feb 13.
928 A gene mutation in RNA-binding protein 10 is associated with lung adenocarcinoma progression and poor prognosis.Oncol Lett. 2018 Nov;16(5):6283-6292. doi: 10.3892/ol.2018.9496. Epub 2018 Sep 24.
929 Overexpression of RCC2 Enhances Cell Motility and Promotes Tumor Metastasis in Lung Adenocarcinoma by Inducing Epithelial-Mesenchymal Transition.Clin Cancer Res. 2017 Sep 15;23(18):5598-5610. doi: 10.1158/1078-0432.CCR-16-2909. Epub 2017 Jun 12.
930 LINC01419 promotes cell proliferation and metastasis in lung adenocarcinoma via sponging miR-519b-3p to up-regulate RCCD1.Biochem Biophys Res Commun. 2019 Nov 26;520(1):107-114. doi: 10.1016/j.bbrc.2019.09.090. Epub 2019 Sep 30.
931 RDM1 plays an oncogenic role in human lung adenocarcinoma cells.Sci Rep. 2018 Aug 1;8(1):11525. doi: 10.1038/s41598-018-30071-y.
932 REG I gene expression is linked with the poor prognosis of lung adenocarcinoma and squamous cell carcinoma patients via discrete mechanisms.Oncol Rep. 2013 Dec;30(6):2625-31. doi: 10.3892/or.2013.2739. Epub 2013 Sep 19.
933 Increased resistin suggests poor prognosis and promotes development of lung adenocarcinoma.Oncol Rep. 2018 Dec;40(6):3392-3404. doi: 10.3892/or.2018.6736. Epub 2018 Sep 26.
934 RFC3 induces epithelialmesenchymal transition in lung adenocarcinoma cells through the Wnt/catenin pathway and possesses prognostic value in lung adenocarcinoma.Int J Mol Med. 2019 Dec;44(6):2276-2288. doi: 10.3892/ijmm.2019.4386. Epub 2019 Oct 29.
935 Skp2 expression has different clinicopathological and prognostic implications in lung adenocarcinoma and squamous cell carcinoma.Oncol Lett. 2018 Sep;16(3):2873-2880. doi: 10.3892/ol.2018.9000. Epub 2018 Jun 20.
936 Hsa-mir-182 suppresses lung tumorigenesis through down regulation of RGS17 expression in vitro.Biochem Biophys Res Commun. 2010 May 28;396(2):501-7. doi: 10.1016/j.bbrc.2010.04.127. Epub 2010 Apr 24.
937 Clinical Value and Prospective Pathway Signaling of MicroRNA-375 in Lung Adenocarcinoma: A Study Based on the Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO) and Bioinformatics Analysis.Med Sci Monit. 2017 May 23;23:2453-2464. doi: 10.12659/msm.901460.
938 Ruthenium methylimidazole complexes induced apoptosis in lung cancer A549 cells through intrinsic mitochondrial pathway.Biochimie. 2012 Feb;94(2):345-53. doi: 10.1016/j.biochi.2011.07.025. Epub 2011 Jul 28.
939 The human Bcl-2 family member Bcl-rambo and voltage-dependent anion channels manifest a genetic interaction in Drosophila and cooperatively promote the activation of effector caspases in human cultured cells.Exp Cell Res. 2019 Aug 15;381(2):223-234. doi: 10.1016/j.yexcr.2019.05.015. Epub 2019 May 15.
940 Association of PD-1 polymorphisms with the risk and prognosis of lung adenocarcinoma in the northeastern Chinese Han population.BMC Med Genet. 2019 Nov 12;20(1):177. doi: 10.1186/s12881-019-0914-8.
941 Phosphorylation of Mig6 negatively regulates the ubiquitination and degradation of EGFR mutants in lung adenocarcinoma cell lines.Cell Signal. 2018 Mar;43:21-31. doi: 10.1016/j.cellsig.2017.11.006. Epub 2017 Dec 2.
942 Downregulation of ribosomal protein S6 inhibits the growth of non-small cell lung cancer by inducing cell cycle arrest, rather than apoptosis.Cancer Lett. 2014 Nov 28;354(2):378-89. doi: 10.1016/j.canlet.2014.08.045. Epub 2014 Sep 6.
943 Methylation and gene silencing of the Ras-related GTPase gene in lung and breast cancers. Ann Surg Oncol. 2007 Apr;14(4):1397-404. doi: 10.1245/s10434-006-9089-6. Epub 2006 Dec 29.
944 RUFY3 Predicts Poor Prognosis and Promotes Metastasis through Epithelial-mesenchymal Transition in Lung Adenocarcinoma.J Cancer. 2019 Oct 17;10(25):6278-6285. doi: 10.7150/jca.35072. eCollection 2019.
945 RUVBL1, a novel C-RAF-binding protein, activates the RAF/MEK/ERK pathway to promote lung cancer tumorigenesis.Biochem Biophys Res Commun. 2018 Apr 15;498(4):932-939. doi: 10.1016/j.bbrc.2018.03.084. Epub 2018 Mar 15.
946 Up-Regulation of S100A11 in Lung Adenocarcinoma - Its Potential Relationship with Cancer Progression.PLoS One. 2015 Nov 6;10(11):e0142642. doi: 10.1371/journal.pone.0142642. eCollection 2015.
947 S100A7 promotes lung adenocarcinoma to squamous carcinoma transdifferentiation, and its expression is differentially regulated by the Hippo-YAP pathway in lung cancer cells.Oncotarget. 2017 Apr 11;8(15):24804-24814. doi: 10.18632/oncotarget.15063.
948 Increased S100A15 expression and decreased DNA methylation of its gene promoter are involved in high metastasis potential and poor outcome of lung adenocarcinoma.Oncotarget. 2017 Jul 11;8(28):45710-45724. doi: 10.18632/oncotarget.17391.
949 Identification of genes associated with matrix metalloproteinases in invasive lung adenocarcinoma.Oncol Lett. 2018 Jul;16(1):123-130. doi: 10.3892/ol.2018.8683. Epub 2018 May 10.
950 SAMHD1 is down regulated in lung cancer by methylation and inhibits tumor cell proliferation.Biochem Biophys Res Commun. 2014 Dec 12;455(3-4):229-33. doi: 10.1016/j.bbrc.2014.10.153. Epub 2014 Nov 6.
951 SASS6 overexpression is associated with mitotic chromosomal abnormalities and a poor prognosis in patients with colorectal cancer.Oncol Rep. 2015 Aug;34(2):727-38. doi: 10.3892/or.2015.4014. Epub 2015 May 28.
952 Exploration of differentially expressed plasma proteins in patients with lung adenocarcinoma using iTRAQ-coupled 2D LC-MS/MS.Clin Respir J. 2018 Jun;12(6):2036-2045. doi: 10.1111/crj.12771. Epub 2018 Feb 21.
953 MDA-9/Syntenin-Slug transcriptional complex promote epithelial-mesenchymal transition and invasion/metastasis in lung adenocarcinoma.Oncotarget. 2016 Jan 5;7(1):386-401. doi: 10.18632/oncotarget.6299.
954 SEC31A-ALK Fusion Gene in Lung Adenocarcinoma.Cancer Res Treat. 2016 Jan;48(1):398-402. doi: 10.4143/crt.2014.254. Epub 2015 Feb 17.
955 Semaphorin 5A suppresses the proliferation and migration of lung adenocarcinoma cells.Int J Oncol. 2020 Jan;56(1):165-177. doi: 10.3892/ijo.2019.4932. Epub 2019 Dec 2.
956 Semaphorin 7A promotes EGFR-TKI resistance in EGFR mutant lung adenocarcinoma cells.JCI Insight. 2018 Dec 20;3(24):e123093. doi: 10.1172/jci.insight.123093.
957 Low expression of SerpinB2 is associated with reduced survival in lung adenocarcinomas.Oncotarget. 2017 Oct 3;8(53):90706-90718. doi: 10.18632/oncotarget.21456. eCollection 2017 Oct 31.
958 miR-21-5p promotes lung adenocarcinoma progression partially through targeting SET/TAF-I.Life Sci. 2019 Aug 15;231:116539. doi: 10.1016/j.lfs.2019.06.014. Epub 2019 Jun 6.
959 Association of specific gene mutations derived from machine learning with survival in lung adenocarcinoma.PLoS One. 2018 Nov 12;13(11):e0207204. doi: 10.1371/journal.pone.0207204. eCollection 2018.
960 Stratifin Inhibits SCF(FBW7) Formation and Blocks Ubiquitination of Oncoproteins during the Course of Lung Adenocarcinogenesis.Clin Cancer Res. 2019 May 1;25(9):2809-2820. doi: 10.1158/1078-0432.CCR-18-3631. Epub 2019 Feb 6.
961 Secreted frizzled related protein 1 modulates taxane resistance of human lung adenocarcinoma.Mol Med. 2014 Apr 8;20(1):164-78. doi: 10.2119/molmed.2013.00149.
962 Immunohistochemical analysis and comparison of napsin A, TTF1, SPA and CK7 expression in primary lung adenocarcinoma.Biotech Histochem. 2018;93(5):364-372. doi: 10.1080/10520295.2018.1444790. Epub 2018 Jun 29.
963 Inhibition of human lung adenocarcinoma growth and metastasis by JC polyomavirus-like particles packaged with an SP-B promoter-driven CD59-specific shRNA.Clin Sci (Lond). 2019 Nov 15;133(21):2159-2169. doi: 10.1042/CS20190395.
964 Clinical, pathological and treatment factors associated with the survival of patients with primary pulmonary salivary gland-type tumors.Lung Cancer. 2018 Dec;126:174-181. doi: 10.1016/j.lungcan.2018.11.010. Epub 2018 Nov 10.
965 CREB targets define the gene expression signature of malignancies having reduced levels of the tumor suppressor tristetraprolin.PLoS One. 2014 Dec 26;9(12):e115517. doi: 10.1371/journal.pone.0115517. eCollection 2014.
966 Differential Tks5 isoform expression contributes to metastatic invasion of lung adenocarcinoma.Genes Dev. 2013 Jul 15;27(14):1557-67. doi: 10.1101/gad.222745.113.
967 Expression profiling of ubiquitin-related genes in LKB1 mutant lung adenocarcinoma.Sci Rep. 2018 Sep 5;8(1):13221. doi: 10.1038/s41598-018-31592-2.
968 Shisa3 brakes resistance to EGFR-TKIs in lung adenocarcinoma by suppressing cancer stem cell properties.J Exp Clin Cancer Res. 2019 Dec 4;38(1):481. doi: 10.1186/s13046-019-1486-3.
969 MiR-218-5p Suppresses the Killing Effect of Natural Killer Cell to Lung Adenocarcinoma by Targeting SHMT1.Yonsei Med J. 2019 Jun;60(6):500-508. doi: 10.3349/ymj.2019.60.6.500.
970 SIPA1L3 methylation modifies the benefit of smoking cessation on lung adenocarcinoma survival: an epigenomic-smoking interaction analysis.Mol Oncol. 2019 May;13(5):1235-1248. doi: 10.1002/1878-0261.12482. Epub 2019 Apr 17.
971 The expression profile and clinic significance of the SIX family in non-small cell lung cancer.J Hematol Oncol. 2016 Nov 8;9(1):119. doi: 10.1186/s13045-016-0339-1.
972 Multi-omics facilitated variable selection in Cox-regression model for cancer prognosis prediction.Methods. 2017 Jul 15;124:100-107. doi: 10.1016/j.ymeth.2017.06.010. Epub 2017 Jun 13.
973 Toward stimulating apoptosis in human lung adenocarcinoma cells by novel nano-carmofur compound treatment.Anticancer Drugs. 2021 Jun 1;32(6):657-663. doi: 10.1097/CAD.0000000000000720.
974 When the guardian sleeps: Reactivation of the p53 pathway in cancer.Mutat Res Rev Mutat Res. 2017 Jul;773:1-13. doi: 10.1016/j.mrrev.2017.02.003. Epub 2017 Feb 17.
975 SMAD4 Mutation in Small Cell Transformation of Epidermal Growth Factor Receptor Mutated Lung Adenocarcinoma.Oncologist. 2019 Jan;24(1):9-13. doi: 10.1634/theoncologist.2018-0016. Epub 2018 Nov 9.
976 A functional variant in miR-155 regulation region contributes to lung cancer risk and survival.Oncotarget. 2015 Dec 15;6(40):42781-92. doi: 10.18632/oncotarget.5840.
977 MicroRNA-7 Compromises p53 Protein-dependent Apoptosis by Controlling the Expression of the Chromatin Remodeling Factor SMARCD1.J Biol Chem. 2016 Jan 22;291(4):1877-1889. doi: 10.1074/jbc.M115.667568. Epub 2015 Nov 5.
978 Differential 18F-FDG and 18F-Fluciclovine Uptake Pattern in a Patient With Poorly Differentiated Adenocarcinoma of the Lung and Prostate Cancer Biochemical Recurrence.Clin Nucl Med. 2020 Jan;45(1):e63-e64. doi: 10.1097/RLU.0000000000002781.
979 Common Oncogene Mutations and Novel SND1-BRAF Transcript Fusion in Lung Adenocarcinoma from Never Smokers.Sci Rep. 2015 May 18;5:9755. doi: 10.1038/srep09755.
980 Suppressor of cytokine signalling-2 limits IGF1R-mediated regulation of epithelial-mesenchymal transition in lung adenocarcinoma.Cell Death Dis. 2018 Apr 1;9(4):429. doi: 10.1038/s41419-018-0457-5.
981 Influence of miR-7a and miR-24-3p on the SOX18 transcript in lung adenocarcinoma.Oncol Rep. 2018 Jan;39(1):201-208. doi: 10.3892/or.2017.6077. Epub 2017 Nov 6.
982 A Novel Long Non-Coding RNA, SOX21-AS1, Indicates a Poor Prognosis and Promotes Lung Adenocarcinoma Proliferation.Cell Physiol Biochem. 2017;42(5):1857-1869. doi: 10.1159/000479543. Epub 2017 Jul 27.
983 SOX30 specially prevents Wnt-signaling to suppress metastasis and improve prognosis of lung adenocarcinoma patients.Respir Res. 2018 Dec 4;19(1):241. doi: 10.1186/s12931-018-0952-3.
984 SOX6 suppresses the development of lung adenocarcinoma by regulating expression of p53, p21(CIPI) , cyclin D1 and -catenin.FEBS Open Bio. 2020 Jan;10(1):135-146. doi: 10.1002/2211-5463.12762. Epub 2019 Dec 12.
985 Decreased expression of SOX7 is correlated with poor prognosis in lung adenocarcinoma patients.Pathol Oncol Res. 2012 Oct;18(4):1039-45. doi: 10.1007/s12253-012-9542-8. Epub 2012 Jul 10.
986 SPC25 upregulation increases cancer stem cell properties in non-small cell lung adenocarcinoma cells and independently predicts poor survival.Biomed Pharmacother. 2018 Apr;100:233-239. doi: 10.1016/j.biopha.2018.02.015. Epub 2018 Feb 16.
987 SPOP regulates the DNA damage response and lung adenocarcinoma cell response to radiation.Am J Cancer Res. 2019 Jul 1;9(7):1469-1483. eCollection 2019.
988 SPRR1B overexpression enhances entry of cells into the G0 phase of the cell cycle.Am J Physiol Lung Cell Mol Physiol. 2003 Oct;285(4):L889-98. doi: 10.1152/ajplung.00065.2003. Epub 2003 Jun 27.
989 miR-150 promotes the proliferation and migration of lung cancer cells by targeting SRC kinase signalling inhibitor 1.Eur J Cancer. 2014 Mar;50(5):1013-24. doi: 10.1016/j.ejca.2013.12.024. Epub 2014 Jan 20.
990 STIP1 Regulates Proliferation and Migration of Lung Adenocarcinoma Through JAK2/STAT3 Signaling Pathway.Cancer Manag Res. 2019 Nov 29;11:10061-10072. doi: 10.2147/CMAR.S233758. eCollection 2019.
991 STK24 expression is modulated by DNA copy number/methylation in lung adenocarcinoma and predicts poor survival.Future Oncol. 2018 Sep;14(22):2253-2263. doi: 10.2217/fon-2018-0126. Epub 2018 Mar 20.
992 SUMO1 promotes the proliferation and invasion of non-small cell lung cancer cells by regulating NF-B.Thorac Cancer. 2019 Jan;10(1):33-40. doi: 10.1111/1759-7714.12895. Epub 2018 Nov 4.
993 SUN1 silencing inhibits cell growth through G0/G1 phase arrest in lung adenocarcinoma.Onco Targets Ther. 2017 Jun 2;10:2825-2833. doi: 10.2147/OTT.S79727. eCollection 2017.
994 The transcriptional repression activity of STAF65 is facilitated by promoter tethering and nuclear import of class IIa histone deacetylases.Biochim Biophys Acta. 2014 Jul;1839(7):579-91. doi: 10.1016/j.bbagrm.2014.05.007. Epub 2014 May 19.
995 Identification of SUV39H2 as a potential oncogene in lung adenocarcinoma.Clin Epigenetics. 2018 Oct 22;10(1):129. doi: 10.1186/s13148-018-0562-4.
996 Identification SYT13 as a novel biomarker in lung adenocarcinoma.J Cell Biochem. 2020 Feb;121(2):963-973. doi: 10.1002/jcb.29224. Epub 2019 Oct 17.
997 TCF19 contributes to cell proliferation of non-small cell lung cancer by inhibiting FOXO1.Cell Biol Int. 2019 Dec;43(12):1416-1424. doi: 10.1002/cbin.11189. Epub 2019 Jul 11.
998 Prognostic significance of TCF21 mRNA expression in patients with lung adenocarcinoma.Sci Rep. 2017 May 17;7(1):2027. doi: 10.1038/s41598-017-02290-2.
999 Expression of TDRD9 in a subset of lung carcinomas by CpG island hypomethylation protects from DNA damage.Oncotarget. 2017 Nov 27;9(11):9618-9631. doi: 10.18632/oncotarget.22709. eCollection 2018 Feb 9.
1000 TEAD4 exerts pro-metastatic effects and is negatively regulated by miR6839-3p in lung adenocarcinoma progression.J Cell Mol Med. 2018 Jul;22(7):3560-3571. doi: 10.1111/jcmm.13634. Epub 2018 Apr 18.
1001 Identification of dysregulated long non-coding RNAs/microRNAs/mRNAs in TNM I stage lung adenocarcinoma.Oncotarget. 2017 Jun 16;8(31):51703-51718. doi: 10.18632/oncotarget.18512. eCollection 2017 Aug 1.
1002 Mitochondrial transcription factor A regulated ionizing radiation-induced mitochondrial biogenesis in human lung adenocarcinoma A549 cells.J Radiat Res. 2013 Nov 1;54(6):998-1004. doi: 10.1093/jrr/rrt046. Epub 2013 May 3.
1003 TFAP2B overexpression contributes to tumor growth and a poor prognosis of human lung adenocarcinoma through modulation of ERK and VEGF/PEDF signaling.Mol Cancer. 2014 Apr 26;13:89. doi: 10.1186/1476-4598-13-89.
1004 Upregulation of microRNA-137 expression by Slug promotes tumor invasion and metastasis of non-small cell lung cancer cells through suppression of TFAP2C.Cancer Lett. 2017 Aug 28;402:190-202. doi: 10.1016/j.canlet.2017.06.002. Epub 2017 Jun 10.
1005 NetSig: network-based discovery from cancer genomes.Nat Methods. 2018 Jan;15(1):61-66. doi: 10.1038/nmeth.4514. Epub 2017 Dec 4.
1006 A novel small-molecule inhibitor of trefoil factor 3 (TFF3) potentiates MEK1/2 inhibition in lung adenocarcinoma.Oncogenesis. 2019 Nov 4;8(11):65. doi: 10.1038/s41389-019-0173-8.
1007 THAP7 promotes cell proliferation by regulating the G1/S phase transition via epigenetically silencing p21 in lung adenocarcinoma.Onco Targets Ther. 2019 Jul 12;12:5651-5660. doi: 10.2147/OTT.S208908. eCollection 2019.
1008 Differential Expression Pattern of THBS1 and THBS2 in Lung Cancer: Clinical Outcome and a Systematic-Analysis of Microarray Databases.PLoS One. 2016 Aug 11;11(8):e0161007. doi: 10.1371/journal.pone.0161007. eCollection 2016.
1009 High expression of synthesis of cytochrome c oxidase 2 and TP53-induced glycolysis and apoptosis regulator can predict poor prognosis in human lung adenocarcinoma.Hum Pathol. 2018 Jul;77:54-62. doi: 10.1016/j.humpath.2017.12.029. Epub 2018 Apr 7.
1010 Trichostatin A suppresses lung adenocarcinoma development in Grg1 overexpressing transgenic mice.Biochem Biophys Res Commun. 2015 Aug 7;463(4):1230-6. doi: 10.1016/j.bbrc.2015.06.090. Epub 2015 Jun 15.
1011 TM4SF4 overexpression in radiation-resistant lung carcinoma cells activates IGF1R via elevation of IGF1.Oncotarget. 2014 Oct 30;5(20):9823-37. doi: 10.18632/oncotarget.2450.
1012 Identification of a novel TMEM106B-ROS1 fusion variant in lung adenocarcinoma by comprehensive genomic profiling.Lung Cancer. 2015 Jun;88(3):352-4. doi: 10.1016/j.lungcan.2015.03.014. Epub 2015 Mar 21.
1013 Decoy Receptor 3 Expression Is Associated With Wild-Type EGFR Status, Poor Differentiation of Tumor, and Unfavorable Patient Outcome.Am J Clin Pathol. 2019 Jul 5;152(2):207-216. doi: 10.1093/ajcp/aqz035.
1014 Integrated analysis of dysregulated long non-coding RNAs/microRNAs/mRNAs in metastasis of lung adenocarcinoma.J Transl Med. 2018 Dec 27;16(1):372. doi: 10.1186/s12967-018-1732-z.
1015 TRAF4 overexpression is a common characteristic of human carcinomas.Oncogene. 2007 Jan 4;26(1):142-7. doi: 10.1038/sj.onc.1209762. Epub 2006 Jun 26.
1016 TRIM9 and TRIM67 Are New Targets in Paraneoplastic Cerebellar Degeneration.Cerebellum. 2019 Apr;18(2):245-254. doi: 10.1007/s12311-018-0987-5.
1017 TRIM11 promotes tumor angiogenesis via activation of STAT3/VEGFA signaling in lung adenocarcinoma.Am J Cancer Res. 2019 Sep 1;9(9):2019-2027. eCollection 2019.
1018 Tripartite motif-containing 15 overexpression in non-small cell lung cancer is associated with poor patient prognoses.J Cancer. 2019 Jan 29;10(4):843-852. doi: 10.7150/jca.27856. eCollection 2019.
1019 TRIM25 is associated with cisplatin resistance in non-small-cell lung carcinoma A549cell line via downregulation of 14-3-3.Biochem Biophys Res Commun. 2017 Nov 4;493(1):568-572. doi: 10.1016/j.bbrc.2017.08.151. Epub 2017 Sep 1.
1020 Frequent silencing of the candidate tumor suppressor TRIM58 by promoter methylation in early-stage lung adenocarcinoma.Oncotarget. 2017 Jan 10;8(2):2890-2905. doi: 10.18632/oncotarget.13761.
1021 Thyroid hormone receptor interactor 13 (TRIP13) overexpression associated with tumor progression and poor prognosis in lung adenocarcinoma.Biochem Biophys Res Commun. 2018 May 15;499(3):416-424. doi: 10.1016/j.bbrc.2018.03.129. Epub 2018 Mar 30.
1022 Trophinin-associated protein expression is an independent prognostic biomarker in lung adenocarcinoma.J Thorac Dis. 2019 May;11(5):2043-2050. doi: 10.21037/jtd.2019.04.86.
1023 Increased expression of TTC21A in lung adenocarcinoma infers favorable prognosis and high immune infiltrating level.Int Immunopharmacol. 2020 Jan;78:106077. doi: 10.1016/j.intimp.2019.106077. Epub 2019 Dec 5.
1024 Aggregate analysis based on TCGA: TTN missense mutation correlates with favorable prognosis in lung squamous cell carcinoma.J Cancer Res Clin Oncol. 2019 Apr;145(4):1027-1035. doi: 10.1007/s00432-019-02861-y. Epub 2019 Feb 27.
1025 Promoter methylation of genes in and around the candidate lung cancer susceptibility locus 6q23-25.Cancer Res. 2008 Mar 15;68(6):1707-14. doi: 10.1158/0008-5472.CAN-07-6325.
1026 Overexpression of APC11 predicts worse survival in lung adenocarcinoma.Onco Targets Ther. 2018 Oct 17;11:7125-7132. doi: 10.2147/OTT.S177252. eCollection 2018.
1027 Growth inhibition of KRASand EGFRmutant lung adenocarcinoma by cosuppression of STAT3 and the SRC/ARHGAP35 axis.Oncol Rep. 2018 Sep;40(3):1761-1768. doi: 10.3892/or.2018.6536. Epub 2018 Jul 2.
1028 Molecular profiling of mouse lung tumors: association with tumor progression, lung development, and human lung adenocarcinomas.Oncogene. 2004 Feb 5;23(5):1166-76. doi: 10.1038/sj.onc.1207234.
1029 Embryo-chondrocyte expressed gene 1, downregulating hypoxia-inducible factor 1alpha, is another marker of lung tumor hypoxia.Acta Pharmacol Sin. 2007 Apr;28(4):549-58. doi: 10.1111/j.1745-7254.2007.00516.x.
1030 MicroRNA-3666 inhibits lung cancer cell proliferation, migration, and invasiveness by targeting BPTF.Biochem Cell Biol. 2019 Aug;97(4):415-422. doi: 10.1139/bcb-2018-0301. Epub 2018 Nov 27.
1031 Regulation of transforming growth factor beta1 by nitric oxide.Cancer Res. 1999 May 1;59(9):2142-9.
1032 Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations.Hum Mol Genet. 2017 Jan 15;26(2):454-465. doi: 10.1093/hmg/ddw414.
1033 Identification of Las2, a major modifier gene affecting the Pas1 mouse lung tumor susceptibility locus.Cancer Res. 2009 Aug 1;69(15):6290-8. doi: 10.1158/0008-5472.CAN-09-0782. Epub 2009 Jul 21.
1034 c-erbB-2/p185-directed therapy in human lung adenocarcinoma.Ann Thorac Surg. 1996 Nov;62(5):1454-9. doi: 10.1016/0003-4975(96)00630-3.
1035 Mucin mRNA expression in lung adenocarcinoma cell lines and tissues.Oncology. 1996 Mar-Apr;53(2):118-26. doi: 10.1159/000227547.
1036 Aberrant expression of caspase 14 in salivary gland carcinomas.J Oral Pathol Med. 2015 Jul;44(6):444-8. doi: 10.1111/jop.12253. Epub 2014 Sep 25.
1037 Distinct HIC1-SIRT1-p53 loop deregulation in lung squamous carcinoma and adenocarcinoma patients.Neoplasia. 2009 Aug;11(8):763-70. doi: 10.1593/neo.09470.
1038 Overexpression of cyclin L2 induces apoptosis and cell-cycle arrest in human lung cancer cells.Chin Med J (Engl). 2007 May 20;120(10):905-9.
1039 MicroRNA-383-5p acts as a prognostic marker and inhibitor of cell proliferation in lung adenocarcinoma by cancerous inhibitor of protein phosphatase 2A.Oncol Lett. 2017 Sep;14(3):3573-3579. doi: 10.3892/ol.2017.6603. Epub 2017 Jul 18.
1040 CLCA2 as a novel immunohistochemical marker for differential diagnosis of squamous cell carcinoma from adenocarcinoma of the lung.Dis Markers. 2014;2014:619273. doi: 10.1155/2014/619273. Epub 2014 Dec 7.
1041 CREB-binding protein regulates lung cancer growth by targeting MAPK and CPSF4 signaling pathway.Mol Oncol. 2016 Feb;10(2):317-29. doi: 10.1016/j.molonc.2015.10.015. Epub 2015 Nov 5.
1042 Tumoral expression of TXR1 and TSP1 predicts overall survival of patients with lung adenocarcinoma treated with first-line docetaxel-gemcitabine regimen.Clin Cancer Res. 2009 Jun 1;15(11):3827-33. doi: 10.1158/1078-0432.CCR-08-3027. Epub 2009 May 12.
1043 CRKL mediates EML4-ALK signaling and is a potential therapeutic target for ALK-rearranged lung adenocarcinoma.Oncotarget. 2016 May 17;7(20):29199-210. doi: 10.18632/oncotarget.8638.
1044 Stratification of resectable lung adenocarcinoma by molecular and pathological risk estimators.Eur J Cancer. 2015 Sep;51(14):1897-903. doi: 10.1016/j.ejca.2015.07.015. Epub 2015 Jul 30.
1045 Smoking-induced CXCL14 expression in the human airway epithelium links chronic obstructive pulmonary disease to lung cancer.Am J Respir Cell Mol Biol. 2013 Sep;49(3):418-25. doi: 10.1165/rcmb.2012-0396OC.
1046 Hyperactivation of ERK by multiple mechanisms is toxic to RTK-RAS mutation-driven lung adenocarcinoma cells.Elife. 2018 Nov 26;7:e33718. doi: 10.7554/eLife.33718.
1047 Cytoplasmic expression of epithelial cell transforming sequence 2 in lung adenocarcinoma and its implications for malignant progression.Lab Invest. 2019 Apr;99(4):551-567. doi: 10.1038/s41374-018-0142-4. Epub 2018 Dec 12.
1048 Neuron-Specific Enolase Is an Independent Prognostic Factor in Resected Lung Adenocarcinoma Patients with Anaplastic Lymphoma Kinase Gene Rearrangements.Med Sci Monit. 2019 Jan 23;25:675-690. doi: 10.12659/MSM.913054.
1049 ERp29 downregulation enhances lung adenocarcinoma cell chemosensitivity to gemcitabine by upregulating HSP27 phosphorylation.Exp Ther Med. 2019 Jan;17(1):817-823. doi: 10.3892/etm.2018.7040. Epub 2018 Nov 30.
1050 FoxA1 and FoxA2 drive gastric differentiation and suppress squamous identity in NKX2-1-negative lung cancer.Elife. 2018 Nov 26;7:e38579. doi: 10.7554/eLife.38579.
1051 Cordycepin induces apoptosis by caveolin-1-mediated JNK regulation of Foxo3a in human lung adenocarcinoma.Oncotarget. 2017 Feb 14;8(7):12211-12224. doi: 10.18632/oncotarget.14661.
1052 Low expression of polypeptide GalNAc N-acetylgalactosaminyl transferase-3 in lung adenocarcinoma: impact on poor prognosis and early recurrence.Br J Cancer. 2004 Jan 26;90(2):436-42. doi: 10.1038/sj.bjc.6601531.
1053 GNAS mutations in primary mucinous and non-mucinous lung adenocarcinomas.Mod Pathol. 2017 Dec;30(12):1720-1727. doi: 10.1038/modpathol.2017.88. Epub 2017 Aug 4.
1054 Increased GOLM1 Expression Independently Predicts Unfavorable Overall Survival and Recurrence-Free Survival in Lung Adenocarcinoma.Cancer Control. 2018 Jan-Mar;25(1):1073274818778001. doi: 10.1177/1073274818778001.
1055 Quinacrine Inhibits ICAM-1 Transcription by Blocking DNA Binding of the NF-B Subunit p65 and Sensitizes Human Lung Adenocarcinoma A549 Cells to TNF- and the Fas Ligand.Int J Mol Sci. 2017 Dec 2;18(12):2603. doi: 10.3390/ijms18122603.
1056 The bioenergetic signature of lung adenocarcinomas is a molecular marker of cancer diagnosis and prognosis.Carcinogenesis. 2004 Jul;25(7):1157-63. doi: 10.1093/carcin/bgh113. Epub 2004 Feb 12.
1057 Identification of ING4 (inhibitor of growth 4) as a modulator of docetaxel sensitivity in human lung adenocarcinoma.Mol Med. 2012 Jul 18;18(1):874-86. doi: 10.2119/molmed.2011.00230.
1058 Expression pattern of the scaffold protein IQGAP1 in lung cancer.Oncol Rep. 2005 Mar;13(3):427-31.
1059 Increased KIF15 Expression Predicts a Poor Prognosis in Patients with Lung Adenocarcinoma.Cell Physiol Biochem. 2018;51(1):1-10. doi: 10.1159/000495155. Epub 2018 Nov 15.
1060 Kinesin KIF4A is associated with chemotherapeutic drug resistance by regulating intracellular trafficking of lung resistance-related protein.J Zhejiang Univ Sci B. 2017 Dec.;18(12):1046-1054. doi: 10.1631/jzus.B1700129.
1061 Elevated Krppel-like factor 5 expression in spatiotemporal mouse lungs is similar to human congenital cystic adenomatoid malformation of the lungs.J Int Med Res. 2018 Jul;46(7):2856-2865. doi: 10.1177/0300060518774998. Epub 2018 Jun 13.
1062 Selective assembly of laminin variants by human carcinoma cells.Lab Invest. 1994 Nov;71(5):719-30.
1063 Methylation-specific loop-mediated isothermal amplification for detecting hypermethylated DNA in simplex and multiplex formats.Clin Chem. 2010 Aug;56(8):1287-96. doi: 10.1373/clinchem.2010.143545. Epub 2010 Jun 15.
1064 The chromosome 3p21.3-encoded gene, LIMD1, is a critical tumor suppressor involved in human lung cancer development.Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19932-7. doi: 10.1073/pnas.0805003105. Epub 2008 Dec 5.
1065 Lipase member H is a novel secreted protein selectively upregulated in human lung adenocarcinomas and bronchioloalveolar carcinomas.Biochem Biophys Res Commun. 2014 Jan 24;443(4):1141-7. doi: 10.1016/j.bbrc.2013.12.106. Epub 2013 Dec 28.
1066 Low lamin A expression in lung adenocarcinoma cells from pleural effusions is a pejorative factor associated with high number of metastatic sites and poor Performance status.PLoS One. 2017 Aug 14;12(8):e0183136. doi: 10.1371/journal.pone.0183136. eCollection 2017.
1067 Olmsted syndrome with squamous cell carcinoma of extremities and adenocarcinoma of the lung: failure to detect loricrin gene mutation.Eur J Dermatol. 2003 Nov-Dec;13(6):524-8.
1068 Lumican is overexpressed in lung adenocarcinoma pleural effusions.PLoS One. 2015 May 11;10(5):e0126458. doi: 10.1371/journal.pone.0126458. eCollection 2015.
1069 MACC1 overexpression in carcinomaassociated fibroblasts induces the invasion of lung adenocarcinoma cells via paracrine signaling.Int J Oncol. 2019 Apr;54(4):1367-1375. doi: 10.3892/ijo.2019.4702. Epub 2019 Jan 30.
1070 Epigenetic silencing of human T (brachyury homologue) gene in non-small-cell lung cancer.Biochem Biophys Res Commun. 2008 Jan 11;365(2):221-6. doi: 10.1016/j.bbrc.2007.10.144. Epub 2007 Oct 31.
1071 Reduced selenium-binding protein 1 expression is associated with poor outcome in lung adenocarcinomas.J Pathol. 2004 Mar;202(3):321-9. doi: 10.1002/path.1524.
1072 High glucose promotes tumor cell proliferation and migration in lung adenocarcinoma via the RAGENOXs pathway.Mol Med Rep. 2018 Jun;17(6):8536-8541. doi: 10.3892/mmr.2018.8914. Epub 2018 Apr 23.
1073 Identification of genes whose expression is upregulated in lung adenocarcinoma cells in comparison with type II alveolar cells and bronchiolar epithelial cells in vivo.Oncogene. 2004 Apr 15;23(17):3089-96. doi: 10.1038/sj.onc.1207433.
1074 pH-responsive hybrid nanoparticle with enhanced dissociation characteristic for siRNA delivery.Int J Nanomedicine. 2018 Oct 26;13:6885-6902. doi: 10.2147/IJN.S180119. eCollection 2018.
1075 Genomic markers for malignant progression in pulmonary adenocarcinoma with bronchioloalveolar features.Proc Natl Acad Sci U S A. 2008 Jul 22;105(29):10155-60. doi: 10.1073/pnas.0709618105. Epub 2008 Jul 15.
1076 Placenta-specific protein 8 promotes the proliferation of lung adenocarcinoma PC-9 cells and their tolerance to an epidermal growth factor receptor tyrosine kinase inhibitor by activating the ERK signaling pathway.Oncol Lett. 2019 Nov;18(5):5621-5627. doi: 10.3892/ol.2019.10911. Epub 2019 Sep 24.
1077 Meta-analysis of oncogenic protein kinase Ciota signaling in lung adenocarcinoma.Clin Cancer Res. 2009 Mar 1;15(5):1527-33. doi: 10.1158/1078-0432.CCR-08-2459. Epub 2009 Feb 17.
1078 Arsenic alters cytosine methylation patterns of the promoter of the tumor suppressor gene p53 in human lung cells: a model for a mechanism of carcinogenesis.Mutat Res. 1997 Jun;386(3):263-77. doi: 10.1016/s1383-5742(97)00008-2.
1079 Nonsynonymous single nucleotide polymorphisms in DNA damage repair pathways and lung cancer risk.Cancer. 2010 Feb 15;116(4):896-902. doi: 10.1002/cncr.24850.
1080 miR-938 promotes cell proliferation by regulating RBM5 in lung adenocarcinoma cells.Cell Biol Int. 2020 Jan;44(1):295-305. doi: 10.1002/cbin.11233. Epub 2019 Sep 25.
1081 Cell proliferation and epidermal growth factor signaling in non-small cell lung adenocarcinoma cell lines are dependent on Rin1.J Biol Chem. 2009 Sep 25;284(39):26331-9. doi: 10.1074/jbc.M109.033514. Epub 2009 Jul 1.
1082 Identification of ribosomal protein L19 as a novel tumor antigen recognized by autologous cytotoxic T lymphocytes in lung adenocarcinoma.Cancer Sci. 2010 Jan;101(1):46-53. doi: 10.1111/j.1349-7006.2009.01351.x. Epub 2009 Sep 9.
1083 Overexpression of S100A14 contributes to malignant progression and predicts poor prognosis of lung adenocarcinoma.Thorac Cancer. 2018 Jul;9(7):827-835. doi: 10.1111/1759-7714.12654. Epub 2018 May 7.
1084 Prognostic significance of S100A16 subcellular localization in lung adenocarcinoma.Hum Pathol. 2018 Apr;74:148-155. doi: 10.1016/j.humpath.2018.01.001. Epub 2018 Jan 7.
1085 Selenophosphate synthetase genes from lung adenocarcinoma cells: Sps1 for recycling L-selenocysteine and Sps2 for selenite assimilation.Proc Natl Acad Sci U S A. 2004 Nov 16;101(46):16162-7. doi: 10.1073/pnas.0406313101. Epub 2004 Nov 8.
1086 SERINC2-knockdown inhibits proliferation, migration and invasion in lung adenocarcinoma.Oncol Lett. 2018 Nov;16(5):5916-5922. doi: 10.3892/ol.2018.9403. Epub 2018 Sep 5.
1087 Transcriptional targeting of adenovirus vectors with the squamous cell carcinoma-specific antigen-2 promoter for selective apoptosis induction in lung cancer.Cancer Gene Ther. 2006 Sep;13(9):856-63. doi: 10.1038/sj.cgt.7700953. Epub 2006 May 19.
1088 MiR-224 promotes the chemoresistance of human lung adenocarcinoma cells to cisplatin via regulating G?S transition and apoptosis by targeting p21(WAF1/CIP1).Br J Cancer. 2014 Jul 15;111(2):339-54. doi: 10.1038/bjc.2014.157. Epub 2014 Jun 12.
1089 COP9 signalosome subunit 5 regulates cancer metastasis by deubiquitinating SNAIL.Oncotarget. 2018 Apr 17;9(29):20670-20680. doi: 10.18632/oncotarget.25060. eCollection 2018 Apr 17.
1090 MiR-124 inhibits cell proliferation, migration and invasion by directly targeting SOX9 in lung adenocarcinoma.Oncol Rep. 2016 May;35(5):3115-21. doi: 10.3892/or.2016.4648. Epub 2016 Mar 3.
1091 Spermassociated antigen 4 (SPAG4) as a new cancer marker interacts with Nesprin3 to regulate cell migration in lung carcinoma.Oncol Rep. 2018 Aug;40(2):783-792. doi: 10.3892/or.2018.6473. Epub 2018 Jun 4.
1092 SULFs in human neoplasia: implication as progression and prognosis factors.J Transl Med. 2011 May 21;9:72. doi: 10.1186/1479-5876-9-72.
1093 Transcriptomic Alterations in Lung Adenocarcinoma Unveil New Mechanisms Targeted by the TBX2 Subfamily of Tumor Suppressor Genes.Front Oncol. 2018 Oct 30;8:482. doi: 10.3389/fonc.2018.00482. eCollection 2018.
1094 Grg1 acts as a lung-specific oncogene in a transgenic mouse model.Cancer Res. 2006 Feb 1;66(3):1294-301. doi: 10.1158/0008-5472.CAN-05-1634.
1095 The upregulation of TMPRSS4, partly ascribed to the downregulation of miR?25a?p, promotes the growth of human lung adenocarcinoma via the NFB signaling pathway.Int J Oncol. 2018 Jul;53(1):148-158. doi: 10.3892/ijo.2018.4396. Epub 2018 May 7.
1096 Growth inhibition and radiosensitization of glioblastoma and lung cancer cells by small interfering RNA silencing of tumor necrosis factor receptor-associated factor 2.Cancer Res. 2008 Sep 15;68(18):7570-8. doi: 10.1158/0008-5472.CAN-08-0632.
1097 Ethnic differences in frequencies of gene polymorphisms in the MYCL1 region and modulation of lung cancer patients' survival.Lung Cancer. 2007 Mar;55(3):271-7. doi: 10.1016/j.lungcan.2006.10.023. Epub 2006 Dec 4.
1098 Ras mutations in United Kingdom examples of oral malignancies are infrequent.Int J Cancer. 1991 May 30;48(3):409-12. doi: 10.1002/ijc.2910480318.