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CXCR7 maintains osteosarcoma invasion after CXCR4 suppression in bone marrow microenvironment.Tumour Biol. 2017 May;39(5):1010428317701631. doi: 10.1177/1010428317701631.
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Genome-wide RNAi screening identifies TMIGD3 isoform1 as a suppressor of NF-B and osteosarcoma progression.Nat Commun. 2016 Nov 25;7:13561. doi: 10.1038/ncomms13561.
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Artemisinin inhibits angiogenesis by regulating p38 MAPK/CREB/TSP-1 signaling pathway in osteosarcoma.J Cell Biochem. 2019 Jul;120(7):11462-11470. doi: 10.1002/jcb.28424. Epub 2019 Feb 11.
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Mutant IDH1 Dysregulates the Differentiation of Mesenchymal Stem Cells in Association with Gene-Specific Histone Modifications to Cartilage- and Bone-Related Genes. PLoS One. 2015 Jul 10;10(7):e0131998.
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Long non-coding RNA small nucleolar RNA host gene 12 (SNHG12) promotes cell proliferation and migration by upregulating angiomotin gene expression in human osteosarcoma cells.Tumour Biol. 2016 Mar;37(3):4065-73. doi: 10.1007/s13277-015-4256-7. Epub 2015 Oct 20.
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Overexpressing circular RNA hsa_circ_0002052 impairs osteosarcoma progression via inhibiting Wnt/-catenin pathway by regulating miR-1205/APC2 axis.Biochem Biophys Res Commun. 2018 Aug 25;502(4):465-471. doi: 10.1016/j.bbrc.2018.05.184. Epub 2018 Jun 5.
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MicroRNA-765 sensitizes osteosarcoma cells to cisplatin via downregulating APE1 expression.Onco Targets Ther. 2019 Sep 3;12:7203-7214. doi: 10.2147/OTT.S194800. eCollection 2019.
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MicroRNA-488 inhibits proliferation, invasion and EMT in osteosarcoma cell lines by targeting aquaporin 3.Int J Oncol. 2018 Oct;53(4):1493-1504. doi: 10.3892/ijo.2018.4483. Epub 2018 Jul 16.
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Hypoxic Proliferation of Osteosarcoma Cells Depends on Arginase II.Cell Physiol Biochem. 2016;39(2):802-13. doi: 10.1159/000447790. Epub 2016 Aug 1.
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Lung cells support osteosarcoma cell migration and survival.BMC Cancer. 2017 Jan 25;17(1):78. doi: 10.1186/s12885-017-3047-5.
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Upregulation of bone morphogenetic protein 2 ( Bmp2) in dorsal root ganglion in a rat model of bone cancer pain.Mol Pain. 2019 Jan-Dec;15:1744806918824250. doi: 10.1177/1744806918824250.
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The effect of bone morphogenetic protein-7 on the expression of type I inositol 1,4,5-trisphosphate receptor in G-292 osteosarcoma cells and primary osteoblast cultures.Arch Oral Biol. 2000 Feb;45(2):159-66. doi: 10.1016/s0003-9969(99)00122-3.
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The Overexpression of CARM1 Promotes Human Osteosarcoma Cell Proliferation through the pGSK3/-Catenin/cyclinD1 Signaling Pathway.Int J Biol Sci. 2017 Jul 18;13(8):976-984. doi: 10.7150/ijbs.19191. eCollection 2017.
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CCN2 promotes drug resistance in osteosarcoma by enhancing ABCG2 expression.J Cell Physiol. 2019 Jun;234(6):9297-9307. doi: 10.1002/jcp.27611. Epub 2018 Oct 14.
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An Unexpected Role of Hyaluronic Acid in Trafficking siRNA Across the Cellular Barrier: The First Biomimetic, Anionic, Non-Viral Transfection Method.Angew Chem Int Ed Engl. 2019 Feb 25;58(9):2815-2819. doi: 10.1002/anie.201900099. Epub 2019 Jan 31.
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Effectiveness of multi-drug regimen chemotherapy treatment in osteosarcoma patients: a network meta-analysis of randomized controlled trials.J Orthop Surg Res. 2017 Mar 29;12(1):52. doi: 10.1186/s13018-017-0544-9.
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Diosgenin exerts its tumor suppressive function via inhibition of Cdc20 in osteosarcoma cells.Cell Cycle. 2019 Feb;18(3):346-358. doi: 10.1080/15384101.2019.1568748. Epub 2019 Jan 22.
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The cyclin-dependent kinase inhibitor flavopiridol (alvocidib) inhibits metastasis of human osteosarcoma cells.Oncotarget. 2018 May 4;9(34):23505-23518. doi: 10.18632/oncotarget.25239. eCollection 2018 May 4.
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Transcriptional activation of CBF by CDK11(p110) is necessary to promote osteosarcoma cell proliferation.Cell Commun Signal. 2019 Oct 14;17(1):125. doi: 10.1186/s12964-019-0440-5.
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miR?94 inhibits cell proliferation and metastasis via targeting of CDK6 in osteosarcoma.Mol Med Rep. 2017 Dec;16(6):8627-8634. doi: 10.3892/mmr.2017.7709. Epub 2017 Oct 4.
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Downregulation of microRNA-95-3p suppresses cell growth of osteosarcoma via CDKN1A/p21 expression.Oncol Rep. 2018 Jan;39(1):289-297. doi: 10.3892/or.2017.6065. Epub 2017 Nov 1.
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CEACAM6 is associated with osteosarcoma metastasis and facilitates epithelial-mesenchymal transition in osteosarcoma cells.Onco Targets Ther. 2018 May 28;11:3159-3166. doi: 10.2147/OTT.S161807. eCollection 2018.
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Cry 1 Regulates the Clock Gene Network and Promotes Proliferation and Migration Via the Akt/P53/P21 Pathway in Human Osteosarcoma Cells.J Cancer. 2018 Jun 14;9(14):2480-2491. doi: 10.7150/jca.25213. eCollection 2018.
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Cryptochrome 2 (CRY2) Suppresses Proliferation and Migration and Regulates Clock Gene Network in Osteosarcoma Cells.Med Sci Monit. 2018 Jun 7;24:3856-3862. doi: 10.12659/MSM.908596.
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CSE1L interaction with MSH6 promotes osteosarcoma progression and predicts poor patient survival.Sci Rep. 2017 Apr 7;7:46238. doi: 10.1038/srep46238.
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Downregulation of DEPTOR inhibits the proliferation, migration, and survival of osteosarcoma through PI3K/Akt/mTOR pathway.Onco Targets Ther. 2017 Sep 8;10:4379-4391. doi: 10.2147/OTT.S143518. eCollection 2017.
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DGKZ Acts as a Potential Oncogene in Osteosarcoma Proliferation Through Its Possible Interaction With ERK1/2 and MYC Pathway.Front Oncol. 2019 Jan 4;8:655. doi: 10.3389/fonc.2018.00655. eCollection 2018.
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LncRNA DLX6-AS1/miR-129-5p/DLK1 axis aggravates stemness of osteosarcoma through Wnt signaling.Biochem Biophys Res Commun. 2018 Dec 9;507(1-4):260-266. doi: 10.1016/j.bbrc.2018.11.019. Epub 2018 Nov 13.
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A humanized bone microenvironment uncovers HIF2 alpha as a latent marker for osteosarcoma.Acta Biomater. 2019 Apr 15;89:372-381. doi: 10.1016/j.actbio.2019.02.051. Epub 2019 Mar 2.
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MicroRNA-448 suppresses osteosarcoma cell proliferation and invasion through targeting EPHA7.PLoS One. 2017 Jun 12;12(6):e0175553. doi: 10.1371/journal.pone.0175553. eCollection 2017.
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Kinesins in MAPK cascade: How kinesin motors are involved in the MAPK pathway?.Gene. 2019 Feb 5;684:1-9. doi: 10.1016/j.gene.2018.10.042. Epub 2018 Oct 17.
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Clinicopathological and prognostic values of ErbB receptor family amplification in primary osteosarcoma.Scand J Clin Lab Invest. 2019 Dec;79(8):601-612. doi: 10.1080/00365513.2019.1683764. Epub 2019 Oct 30.
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miR-219a-5p represses migration and invasion of osteosarcoma cells via targeting EYA2.Artif Cells Nanomed Biotechnol. 2018;46(sup3):S1004-S1010. doi: 10.1080/21691401.2018.1525391. Epub 2018 Nov 19.
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In-vitro cytocompatibility of dental resin monomers on osteoblast-like cells.J Dent. 2017 Oct;65:76-82. doi: 10.1016/j.jdent.2017.07.008. Epub 2017 Jul 12.
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Different effects of G-protein-coupled receptor 120 (GPR120) and GPR40 on cell motile activity of highly migratory osteosarcoma cells.Biochem Biophys Res Commun. 2017 Mar 11;484(3):675-680. doi: 10.1016/j.bbrc.2017.01.175. Epub 2017 Jan 31.
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FOS Expression in Osteoid Osteoma and Osteoblastoma: A Valuable Ancillary Diagnostic Tool.Am J Surg Pathol. 2019 Dec;43(12):1661-1667. doi: 10.1097/PAS.0000000000001355.
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miR-143-3p inhibits the proliferation, migration and invasion in osteosarcoma by targeting FOSL2.Sci Rep. 2018 Jan 12;8(1):606. doi: 10.1038/s41598-017-18739-3.
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Identification of Key Genes and miRNAs in Osteosarcoma Patients with Chemoresistance by Bioinformatics Analysis.Biomed Res Int. 2018 Apr 22;2018:4761064. doi: 10.1155/2018/4761064. eCollection 2018.
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Human Galectin-1 and its inhibitors: Privileged target for cancer and HIV. Mini Rev Med Chem. 2019 Mar 4.
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miR-141-3p suppresses proliferation and promotes apoptosis by targeting GLI2 in osteosarcoma cells.Oncol Rep. 2018 Feb;39(2):747-754. doi: 10.3892/or.2017.6150. Epub 2017 Dec 12.
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Targeting Glycoprotein NMB With Antibody-Drug Conjugate, Glembatumumab Vedotin, for the Treatment of Osteosarcoma.Pediatr Blood Cancer. 2016 Jan;63(1):32-8. doi: 10.1002/pbc.25688. Epub 2015 Aug 25.
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Small interfering RNA-mediated silencing of G-protein-coupled receptor 137 inhibits growth of osteosarcoma cells.J Bone Oncol. 2017 Dec 23;11:17-22. doi: 10.1016/j.jbo.2017.12.001. eCollection 2018 Jun.
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GRM4 inhibits the proliferation, migration, and invasion of human osteosarcoma cells through interaction with CBX4.Biosci Biotechnol Biochem. 2020 Feb;84(2):279-289. doi: 10.1080/09168451.2019.1673147. Epub 2019 Oct 4.
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HDAC2 depletion promotes osteosarcoma's stemness both in vitro and in vivo: a study on a putative new target for CSCs directed therapy.J Exp Clin Cancer Res. 2018 Dec 3;37(1):296. doi: 10.1186/s13046-018-0978-x.
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Prognostic role of HSF1 overexpression in solid tumors: a pooled analysis of 3,159 patients.Onco Targets Ther. 2018 Jan 17;11:383-393. doi: 10.2147/OTT.S153682. eCollection 2018.
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Glucagon Decreases IGF-1 Bioactivity in Humans, Independently of Insulin, by Modulating Its Binding Proteins.J Clin Endocrinol Metab. 2017 Sep 1;102(9):3480-3490. doi: 10.1210/jc.2017-00558.
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The Wilms tumor protein WT1 stimulates transcription of the gene encoding insulin-like growth factor binding protein 5 (IGFBP5).Gene. 2017 Jul 1;619:21-29. doi: 10.1016/j.gene.2017.03.037. Epub 2017 Mar 30.
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Synergistic suppression of a disintegrin acurhagin-C in combination with AZD4547 and reparixin on terminating development for human osteosarcoma MG-63 cell.Biochem Biophys Res Commun. 2017 Oct 21;492(3):513-519. doi: 10.1016/j.bbrc.2017.08.046. Epub 2017 Aug 18.
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Observation of significant biomarkers in osteosarcoma via integrating module- identification method with attract.Cancer Biomark. 2017 Jul 19;20(1):87-93. doi: 10.3233/CBM-170144.
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Inhibition of STAT3 blocks protein synthesis and tumor metastasis in osteosarcoma cells.J Exp Clin Cancer Res. 2018 Oct 4;37(1):244. doi: 10.1186/s13046-018-0914-0.
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Single-walled carbon nanotube: One specific inhibitor of cancer stem cells in osteosarcoma upon downregulation of the TGF1 signaling.Biomaterials. 2017 Dec;149:29-40. doi: 10.1016/j.biomaterials.2017.09.032. Epub 2017 Sep 26.
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MALT1 is a critical mediator of PAR1-driven NF-B activation and metastasis in multiple tumor types.Oncogene. 2019 Dec;38(49):7384-7398. doi: 10.1038/s41388-019-0958-4. Epub 2019 Aug 16.
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miR-187 inhibits tumor growth and invasion by directly targeting MAPK12 in osteosarcoma.Exp Ther Med. 2017 Aug;14(2):1045-1050. doi: 10.3892/etm.2017.4624. Epub 2017 Jun 16.
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miR?4c?p acts as a tumor suppressor gene in osteosarcoma by targeting MARCKS.Mol Med Rep. 2017 Mar;15(3):1204-1210. doi: 10.3892/mmr.2017.6108. Epub 2017 Jan 11.
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Overexpression of long non-coding RNA MFI2 promotes cell proliferation and suppresses apoptosis in human osteosarcoma.Oncol Rep. 2016 Oct;36(4):2033-40. doi: 10.3892/or.2016.5013. Epub 2016 Aug 11.
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miR-134 inhibits osteosarcoma cell invasion and metastasis through targeting MMP1 and MMP3 invitro and invivo.FEBS Lett. 2019 May;593(10):1089-1101. doi: 10.1002/1873-3468.13387. Epub 2019 May 8.
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Knockdown of MSI1 inhibited the cell proliferation of human osteosarcoma cells by targeting p21 and p27.Oncol Lett. 2017 Nov;14(5):5271-5278. doi: 10.3892/ol.2017.6870. Epub 2017 Sep 1.
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Overexpression of GRIM-19 accelerates radiation-induced osteosarcoma cells apoptosis by p53 stabilization.Life Sci. 2018 Sep 1;208:232-238. doi: 10.1016/j.lfs.2018.07.015. Epub 2018 Jul 10.
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Silencing of NUF2 inhibits proliferation of human osteosarcoma Saos-2 cells.Eur Rev Med Pharmacol Sci. 2016;20(6):1071-9.
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Highly-expressed P2X7 receptor promotes growth and metastasis of human HOS/MNNG osteosarcoma cells via PI3K/Akt/GSK3/-catenin and mTOR/HIF1/VEGF signaling.Int J Cancer. 2019 Aug 15;145(4):1068-1082. doi: 10.1002/ijc.32207. Epub 2019 Mar 18.
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CCEPR is a novel clinical biomarker for prognosis and regulates cell proliferation through PCNA in osteosarcoma.J Cell Biochem. 2019 Aug;120(8):12796-12802. doi: 10.1002/jcb.28550. Epub 2019 Mar 12.
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The prognostic significance of circulating serum amyloid A and CXC chemokine ligand 4 in osteosarcoma.Pediatr Blood Cancer. 2017 Dec;64(12):10.1002/pbc.26659. doi: 10.1002/pbc.26659. Epub 2017 May 24.
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LncRNA HIF2PUT inhibited osteosarcoma stem cells proliferation, migration and invasion by regulating HIF2 expression.Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):1342-1348. doi: 10.1080/21691401.2019.1596934.
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PTHR1 May Be Involved in Progression of Osteosarcoma by Regulating miR-124-3p-AR-Tgfb1i1, miR-27a-3p-PPARG-Abca1, and miR-103/590-3p-AXIN2 Axes.DNA Cell Biol. 2019 Nov;38(11):1323-1337. doi: 10.1089/dna.2019.4880. Epub 2019 Sep 19.
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Potential Molecular Mechanisms of AURKB in the Oncogenesis and Progression of Osteosarcoma Cells: A Label-Free Quantitative Proteomics Analysis.Technol Cancer Res Treat. 2018 Jan-Dec;18:1533033819853262. doi: 10.1177/1533033819853262.
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Down-regulation of RBP-J mediated by microRNA-133a suppresses dendritic cells and functions as a potential tumor suppressor in osteosarcoma.Exp Cell Res. 2016 Dec 10;349(2):264-272. doi: 10.1016/j.yexcr.2016.10.019. Epub 2016 Oct 26.
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Promotion of tumour proliferation, migration and invasion by miR-92b in targeting RECK in osteosarcoma.Clin Sci (Lond). 2016 Jun 1;130(11):921-30. doi: 10.1042/CS20150509. Epub 2016 Mar 18.
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Meta-analysis of clinical significance of p53 protein expression in patients with osteosarcoma.Future Oncol. 2017 Sep;13(21):1883-1891. doi: 10.2217/fon-2017-0180. Epub 2017 Aug 2.
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microRNA-138-5p as a Worse Prognosis Biomarker in Pediatric, Adolescent, and Young Adult Osteosarcoma.Pathol Oncol Res. 2020 Apr;26(2):877-883. doi: 10.1007/s12253-019-00633-0. Epub 2019 Mar 12.
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RSF1 functions as an oncogene in osteosarcoma and is regulated by XIST/miR-193a-3p axis.Biomed Pharmacother. 2017 Nov;95:207-214. doi: 10.1016/j.biopha.2017.08.068. Epub 2017 Sep 12.
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MicroRNA-187 Inhibits Growth and Metastasis of Osteosarcoma by Downregulating S100A4.Cancer Invest. 2018 Jan 2;36(1):1-9. doi: 10.1080/07357907.2017.1415348. Epub 2018 Jan 5.
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MiR-20a-5p represses the multi-drug resistance of osteosarcoma by targeting the SDC2 gene.Cancer Cell Int. 2017 Nov 2;17:100. doi: 10.1186/s12935-017-0470-2. eCollection 2017.
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Bidirectional regulation of bone formation by exogenous and osteosarcoma-derived Sema3A.Sci Rep. 2018 May 2;8(1):6877. doi: 10.1038/s41598-018-25290-2.
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Essential role of SH3GL1 in interleukin-6(IL-6)- and vascular endothelial growth factor (VEGF)-triggered p130(cas)-mediated proliferation and migration of osteosarcoma cells.Hum Cell. 2017 Oct;30(4):300-310. doi: 10.1007/s13577-017-0178-6. Epub 2017 Jul 12.
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S-phase kinase-associated protein 2 is involved in epithelial-mesenchymal transition in methotrexate-resistant osteosarcoma cells.Int J Oncol. 2018 Jun;52(6):1841-1852. doi: 10.3892/ijo.2018.4345. Epub 2018 Mar 29.
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Association of SNPs in dopamine and serotonin pathway genes and their interacting genes with temperament traits in Charolais cows.J Appl Genet. 2017 Aug;58(3):363-371. doi: 10.1007/s13353-016-0383-0. Epub 2016 Dec 16.
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SLC34A2 Regulates the Proliferation, Migration, and Invasion of Human Osteosarcoma Cells Through PTEN/PI3K/AKT Signaling.DNA Cell Biol. 2017 Sep;36(9):775-780. doi: 10.1089/dna.2017.3750. Epub 2017 Aug 4.
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Increased SNAT1 is a marker of human osteosarcoma and potential therapeutic target.Oncotarget. 2017 Sep 5;8(45):78930-78939. doi: 10.18632/oncotarget.20693. eCollection 2017 Oct 3.
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SLC3A2 is upregulated in human osteosarcoma and promotes tumor growth through the PI3K/Akt signaling pathway.Oncol Rep. 2017 May;37(5):2575-2582. doi: 10.3892/or.2017.5530. Epub 2017 Mar 27.
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SphK2 over-expression promotes osteosarcoma cell growth.Oncotarget. 2017 Nov 6;8(62):105525-105535. doi: 10.18632/oncotarget.22314. eCollection 2017 Dec 1.
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SPOCK1 promotes the growth of Osteosarcoma cells through mTOR-S6K signaling pathway.Biomed Pharmacother. 2017 Nov;95:564-570. doi: 10.1016/j.biopha.2017.08.116. Epub 2017 Sep 12.
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MiR-193a-3p and miR-193a-5p suppress the metastasis of human osteosarcoma cells by down-regulating Rab27B and SRR, respectively. Clin Exp Metastasis. 2016 Apr;33(4):359-72.
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p27/Kip1 functions as a tumor suppressor and oncoprotein in osteosarcoma.Sci Rep. 2019 Apr 16;9(1):6161. doi: 10.1038/s41598-019-42450-0.
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TROP2 promotes cell proliferation and migration in osteosarcoma through PI3K/AKT signaling.Mol Med Rep. 2018 Aug;18(2):1782-1788. doi: 10.3892/mmr.2018.9083. Epub 2018 May 29.
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Tegavivint and the beta-Catenin/ALDH Axis in Chemotherapy-Resistant and Metastatic Osteosarcoma. J Natl Cancer Inst. 2019 Nov 1;111(11):1216-1227.
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Overexpression of TTRAP inhibits cell growth and induces apoptosis in osteosarcoma cells.BMB Rep. 2013 Feb;46(2):113-8. doi: 10.5483/bmbrep.2013.46.2.150.
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miR-149-5p inhibits cell growth by regulating TWEAK/Fn14/PI3K/AKT pathway and predicts favorable survival in human osteosarcoma.Int J Immunopathol Pharmacol. 2018 Jan-Dec;32:2058738418786656. doi: 10.1177/2058738418786656.
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Author Correction: Bisphosphonate enhances TRAIL sensitivity to human osteosarcoma cells via death receptor 5 upregulation.Exp Mol Med. 2018 Aug 17;50(8):1-3. doi: 10.1038/s12276-018-0127-9.
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miR-24 represses metastasis of human osteosarcoma cells by targeting Ack1 via AKT/MMPs pathway.Biochem Biophys Res Commun. 2017 Apr 29;486(2):211-217. doi: 10.1016/j.bbrc.2017.02.045. Epub 2017 Feb 8.
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Identification of Novel Target for Osteosarcoma by Network Analysis.Med Sci Monit. 2018 Aug 25;24:5914-5924. doi: 10.12659/MSM.909973.
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mTOR signal transduction pathways contribute to TN-C FNIII A1 overexpression by mechanical stress in osteosarcoma cells.Mol Cells. 2014 Feb;37(2):118-25. doi: 10.14348/molcells.2014.2247. Epub 2014 Feb 19.
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DNA-damage response in chromatin of ribosomal genes and the surrounding genome.Gene. 2013 Jun 15;522(2):156-67. doi: 10.1016/j.gene.2013.03.108. Epub 2013 Apr 6.
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siRNA targeting TCTP suppresses osteosarcoma cell growth and induces apoptosis in vitro and in vivo.Biotechnol Appl Biochem. 2016 Jan-Feb;63(1):5-14. doi: 10.1002/bab.1335. Epub 2015 Dec 22.
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The Alzheimer's disease-associated TREM2 gene is regulated by p53 tumor suppressor protein.Neurosci Lett. 2018 Aug 10;681:62-67. doi: 10.1016/j.neulet.2018.05.037. Epub 2018 May 26.
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Capsaicin induces cytotoxicity in human osteosarcoma MG63 cells through TRPV1-dependent and -independent pathways.Cell Cycle. 2019 Jun;18(12):1379-1392. doi: 10.1080/15384101.2019.1618119. Epub 2019 May 29.
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P65-mediated miR-590 inhibition modulates the chemoresistance of osteosarcoma to doxorubicin through targeting wild-type p53-induced phosphatase 1.J Cell Biochem. 2019 Apr;120(4):5652-5665. doi: 10.1002/jcb.27849. Epub 2018 Nov 1.
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miR-1285-3p is a potential prognostic marker in human osteosarcoma and functions as a tumor suppressor by targeting YAP1.Cancer Biomark. 2019;25(1):1-10. doi: 10.3233/CBM-180013.
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miR-422a inhibits osteosarcoma proliferation by targeting BCL2L2 and KRAS.Biosci Rep. 2018 Mar 21;38(2):BSR20170339. doi: 10.1042/BSR20170339. Print 2018 Apr 27.
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Lycorine Induces Apoptosis and G1 Phase Arrest Through ROS/p38 MAPK Signaling Pathway in Human Osteosarcoma Cells In Vitro and In Vivo.Spine (Phila Pa 1976). 2020 Feb 1;45(3):E126-E139. doi: 10.1097/BRS.0000000000003217.
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miR-223-3p Inhibits Human Osteosarcoma Metastasis and Progression by Directly Targeting CDH6.Mol Ther. 2018 May 2;26(5):1299-1312. doi: 10.1016/j.ymthe.2018.03.009. Epub 2018 Mar 14.
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Network Pharmacology Integrated Molecular Docking Reveals the Antiosteosarcoma Mechanism of Biochanin A.Evid Based Complement Alternat Med. 2019 Jan 6;2019:1410495. doi: 10.1155/2019/1410495. eCollection 2019.
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GSK343 induces programmed cell death through the inhibition of EZH2 and FBP1 in osteosarcoma cells.Cancer Biol Ther. 2020;21(3):213-222. doi: 10.1080/15384047.2019.1680061. Epub 2019 Oct 25.
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Clinicopathological and prognostic values of fibronectin and integrin v3 expression in primary osteosarcoma.World J Surg Oncol. 2019 Jan 28;17(1):23. doi: 10.1186/s12957-019-1566-z.
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Avasimibe inhibits tumor growth by targeting FoxM1-AKR1C1 in osteosarcoma.Onco Targets Ther. 2019 Jan 24;12:815-823. doi: 10.2147/OTT.S165647. eCollection 2019.
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HSP90 regulates osteosarcoma cell apoptosis by targeting the p53/TCF-1-mediated transcriptional network.J Cell Physiol. 2020 Apr;235(4):3894-3904. doi: 10.1002/jcp.29283. Epub 2019 Oct 9.
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Histone Demethylase JARID1B Is Overexpressed in Osteosarcoma and Upregulates Cyclin D1 Expression via Demethylation of H3K27me3.Oncol Res. 2018 Apr 10;26(3):373-384. doi: 10.3727/096504017X14939809845080. Epub 2017 May 11.
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Bone marrow-derived mesenchymal stem cell-derived exosomal microRNA-208a promotes osteosarcoma cell proliferation, migration, and invasion.J Cell Physiol. 2020 May;235(5):4734-4745. doi: 10.1002/jcp.29351. Epub 2019 Oct 21.
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Abnormal DNA methylation may contribute to the progression of osteosarcoma.Mol Med Rep. 2018 Jan;17(1):193-199. doi: 10.3892/mmr.2017.7869. Epub 2017 Oct 25.
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SLIT2/ROBO1 axis contributes to the Warburg effect in osteosarcoma through activation of SRC/ERK/c-MYC/PFKFB2 pathway.Cell Death Dis. 2018 Mar 9;9(3):390. doi: 10.1038/s41419-018-0419-y.
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Calcium-sensing receptor activating ERK1/2 and PI3K-Akt pathways to induce the proliferation of osteosarcoma cells.Clin Exp Pharmacol Physiol. 2020 Mar;47(3):517-519. doi: 10.1111/1440-1681.13209. Epub 2019 Nov 24.
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Cyclic Guanosine Monophosphate (cGMP)-Dependent Protein Kinase II Blocks Epidermal Growth Factor (EGF)/Epidermal Growth Factor Receptor (EGFR)-Induced Biological Effects on Osteosarcoma Cells.Med Sci Monit. 2018 Apr 4;24:1997-2002. doi: 10.12659/msm.905892.
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miR-22 inhibits tumor growth and metastasis by targeting ATP citrate lyase: evidence in osteosarcoma, prostate cancer, cervical cancer and lung cancer.Oncotarget. 2016 Jul 12;7(28):44252-44265. doi: 10.18632/oncotarget.10020.
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IAP antagonists sensitize murine osteosarcoma cells to killing by TNF.Oncotarget. 2016 Jun 7;7(23):33866-86. doi: 10.18632/oncotarget.8980.
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MicroRNA-330-3p Expression Indicates Good Prognosis and Suppresses Cell Proliferation by Targeting Bmi-1 in Osteosarcoma.Cell Physiol Biochem. 2018;46(2):442-450. doi: 10.1159/000488612. Epub 2018 Mar 26.
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Gene expression profiling analysis of osteosarcoma cell lines.Mol Med Rep. 2015 Sep;12(3):4266-4272. doi: 10.3892/mmr.2015.3958. Epub 2015 Jun 18.
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CYR61 triggers osteosarcoma metastatic spreading via an IGF1R-dependent EMT-like process.BMC Cancer. 2019 Jan 14;19(1):62. doi: 10.1186/s12885-019-5282-4.
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LDOC1 regulates Wnt5a expression and osteosarcoma cell metastasis and is correlated with the survival of osteosarcoma patients.Tumour Biol. 2017 Feb;39(2):1010428317691188. doi: 10.1177/1010428317691188.
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miR-130b targets NKD2 and regulates the Wnt signaling to promote proliferation and inhibit apoptosis in osteosarcoma cells. Biochem Biophys Res Commun. 2016 Mar 18;471(4):479-85.
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NKX2-2 Suppresses Osteosarcoma Metastasis and Proliferation by Downregulating Multiple Target Genes.J Cancer. 2018 Aug 6;9(17):3067-3077. doi: 10.7150/jca.26382. eCollection 2018.
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miRNA-20a upregulates TAK1 and increases proliferation in osteosarcoma cells.Future Oncol. 2018 Feb;14(5):461-469. doi: 10.2217/fon-2017-0490. Epub 2018 Jan 12.
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Silencing of histone methyltransferase NSD3 reduces cell viability in osteosarcoma with induction of apoptosis.Oncol Rep. 2017 Nov;38(5):2796-2802. doi: 10.3892/or.2017.5936. Epub 2017 Sep 4.
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The miR-15b-5p/PDK4 axis regulates osteosarcoma proliferation through modulation of the Warburg effect.Biochem Biophys Res Commun. 2018 Sep 18;503(4):2749-2757. doi: 10.1016/j.bbrc.2018.08.035. Epub 2018 Aug 6.
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The Function of the Novel Mechanical Activated Ion Channel Piezo1 in the Human Osteosarcoma Cells.Med Sci Monit. 2017 Oct 24;23:5070-5082. doi: 10.12659/msm.906959.
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Expression of Livin and PlGF in human osteosarcoma is associated with tumor progression and clinical outcome.Oncol Lett. 2018 Oct;16(4):4953-4960. doi: 10.3892/ol.2018.9239. Epub 2018 Jul 31.
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miR-142-5p suppresses proliferation and promotes apoptosis of human osteosarcoma cell line, HOS, by targeting PLA2G16 through the ERK1/2 signaling pathway.Oncol Lett. 2019 Jan;17(1):1363-1371. doi: 10.3892/ol.2018.9712. Epub 2018 Nov 15.
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Silencing of CKIP-1 promotes tumor proliferation and cell adhesion-mediated drug resistance via regulating AKT activity in non-Hodgkin's lymphoma.Oncol Rep. 2017 Jan;37(1):622-630. doi: 10.3892/or.2016.5233. Epub 2016 Nov 8.
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miR-200bc/429 Inhibits Osteosarcoma Cell Proliferation and Invasion by Targeting PMP22.Med Sci Monit. 2017 Feb 24;23:1001-1008. doi: 10.12659/msm.900084.
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Expression level of CDC2 gene in osteosarcoma and its clinical significance.Oncol Lett. 2018 May;15(5):7884-7888. doi: 10.3892/ol.2018.8307. Epub 2018 Mar 20.
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MiRNA-543 promotes osteosarcoma cell proliferation and glycolysis by partially suppressing PRMT9 and stabilizing HIF-1 protein.Oncotarget. 2017 Jan 10;8(2):2342-2355. doi: 10.18632/oncotarget.13672.
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Modeling osteosarcoma progression by measuring the connectivity dynamics using an inference of multiple differential modules algorithm.Mol Med Rep. 2017 Aug;16(2):1047-1054. doi: 10.3892/mmr.2017.6703. Epub 2017 Jun 6.
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RNA-binding protein PUM2 suppresses osteosarcoma progression via partly and competitively binding to STARD13 3'UTR with miRNAs.Cell Prolif. 2018 Dec;51(6):e12508. doi: 10.1111/cpr.12508. Epub 2018 Aug 7.
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Long non-coding RNA RAB11B-AS1 prevents osteosarcoma development and progression via its natural antisense transcript RAB11B.Oncotarget. 2018 Jan 13;9(42):26770-26786. doi: 10.18632/oncotarget.24247. eCollection 2018 Jun 1.
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MicroRNA-16 suppressed the invasion and migration of osteosarcoma by directly inhibiting RAB23.Eur Rev Med Pharmacol Sci. 2018 May;22(9):2598-2605. doi: 10.26355/eurrev_201805_14953.
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New 2-Oxoindolin Phosphonates as Novel Agents to Treat Cancer: A Green Synthesis and Molecular Modeling.Molecules. 2018 Aug 8;23(8):1981. doi: 10.3390/molecules23081981.
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RBEL1 is required for osteosarcoma cell proliferation via inhibiting retinoblastoma 1.Mol Med Rep. 2016 Feb;13(2):1275-80. doi: 10.3892/mmr.2015.4670. Epub 2015 Dec 10.
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A new subtype of high-grade mandibular osteosarcoma with RASAL1/MDM2 amplification.Hum Pathol. 2016 Apr;50:70-8. doi: 10.1016/j.humpath.2015.11.012. Epub 2015 Dec 9.
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RASSF4 Overexpression Inhibits the Proliferation, Invasion, EMT, and Wnt Signaling Pathway in Osteosarcoma Cells.Oncol Res. 2017 Jan 2;25(1):83-91. doi: 10.3727/096504016X14719078133447.
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Elevated circulating macrophage inhibitory cytokine 1 is a biological marker for the diagnosis and prognosis of osteosarcoma.Exp Ther Med. 2018 Dec;16(6):4803-4809. doi: 10.3892/etm.2018.6786. Epub 2018 Sep 21.
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Targeting the Wnt/-catenin pathway in human osteosarcoma cells.Oncotarget. 2018 Dec 4;9(95):36780-36792. doi: 10.18632/oncotarget.26377. eCollection 2018 Dec 4.
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Highly expressed ribosomal protein L34 indicates poor prognosis in osteosarcoma and its knockdown suppresses osteosarcoma proliferation probably through translational control.Sci Rep. 2016 Nov 24;6:37690. doi: 10.1038/srep37690.
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Down-regulation of RPS9 Inhibits Osteosarcoma Cell Growth through Inactivation of MAPK Signaling Pathway.J Cancer. 2017 Aug 22;8(14):2720-2728. doi: 10.7150/jca.19130. eCollection 2017.
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Rhotekin 2 silencing inhibits proliferation and induces apoptosis in human osteosarcoma cells.Biosci Rep. 2018 Nov 20;38(6):BSR20181384. doi: 10.1042/BSR20181384. Print 2018 Dec 21.
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Overexpression of SCARA5 inhibits tumor proliferation and invasion in osteosarcoma via suppression of the FAK signaling pathway.Mol Med Rep. 2016 Mar;13(3):2885-91. doi: 10.3892/mmr.2016.4857. Epub 2016 Feb 3.
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2-Methoxyestradiol Affects Mitochondrial Biogenesis Pathway and Succinate Dehydrogenase Complex Flavoprotein Subunit A in Osteosarcoma Cancer Cells.Cancer Genomics Proteomics. 2018 Jan-Feb;15(1):73-89. doi: 10.21873/cgp.20067.
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SUMO-specific protease 2 (SENP2) functions as a tumor suppressor in osteosarcoma via SOX9 degradation.Exp Ther Med. 2018 Dec;16(6):5359-5365. doi: 10.3892/etm.2018.6838. Epub 2018 Oct 9.
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LncRNA SNHG5 promotes the progression of osteosarcoma by sponging the miR-212-3p/SGK3 axis.Cancer Cell Int. 2018 Sep 18;18:141. doi: 10.1186/s12935-018-0641-9. eCollection 2018.
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Siva 1 inhibits proliferation, migration and invasion by phosphorylating Stathmin in ovarian cancer cells.Oncol Lett. 2017 Aug;14(2):1512-1518. doi: 10.3892/ol.2017.6307. Epub 2017 Jun 2.
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TIPE2 sensitizes osteosarcoma cells to cis-platin by down-regulating MDR1 via the TAK1- NF-B and - AP-1 pathways.Mol Immunol. 2018 Sep;101:471-478. doi: 10.1016/j.molimm.2018.08.010. Epub 2018 Aug 14.
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TEAD1 mediates the oncogenic activities of Hippo-YAP1 signaling in osteosarcoma.Biochem Biophys Res Commun. 2017 Jun 24;488(2):297-302. doi: 10.1016/j.bbrc.2017.05.032. Epub 2017 May 5.
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miR-34 inhibits growth and promotes apoptosis of osteosarcoma in nude mice through targetly regulating TGIF2 expression.Biosci Rep. 2018 Jun 12;38(3):BSR20180078. doi: 10.1042/BSR20180078. Print 2018 Jun 29.
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MicroRNA-552 promotes migration and invasion of osteosarcoma through targeting TIMP2.Biochem Biophys Res Commun. 2019 Mar 26;511(1):63-68. doi: 10.1016/j.bbrc.2019.02.007. Epub 2019 Feb 11.
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MicroRNA-138 directly targets TNFAIP8 and acts as a tumor suppressor in osteosarcoma.Exp Ther Med. 2017 Oct;14(4):3665-3673. doi: 10.3892/etm.2017.4947. Epub 2017 Aug 16.
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Identification of a p53 target, CD137L, that mediates growth suppression and immune response of osteosarcoma cells.Sci Rep. 2017 Sep 6;7(1):10739. doi: 10.1038/s41598-017-11208-x.
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Analysis of Minerals Produced by hFOB 1.19 and Saos-2 Cells Using Transmission Electron Microscopy with Energy Dispersive X-ray Microanalysis.J Vis Exp. 2018 Jun 24;(136):57423. doi: 10.3791/57423.
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TopBP1 promotes malignant progression and correlates with poor prognosis in osteosarcoma.Eur Rev Med Pharmacol Sci. 2017 Sep;21(18):4022-4031.
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Migration-inducing gene-7 independently predicts poor prognosis of human osteosarcoma and is associated with vasculogenic mimicry.Exp Cell Res. 2018 Aug 1;369(1):80-89. doi: 10.1016/j.yexcr.2018.05.008. Epub 2018 May 8.
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MicroRNA-107 Promotes Proliferation, Migration, and Invasion of Osteosarcoma Cells by Targeting Tropomyosin 1.Oncol Res. 2017 Sep 21;25(8):1409-1419. doi: 10.3727/096504017X14882829077237. Epub 2017 Mar 8.
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MicroRNA-214 functions as an oncogene in human osteosarcoma by targeting TRAF3.Eur Rev Med Pharmacol Sci. 2018 Aug;22(16):5156-5164. doi: 10.26355/eurrev_201808_15711.
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TRIM2 regulates the development and metastasis of tumorous cells of osteosarcoma.Int J Oncol. 2018 Oct;53(4):1643-1656. doi: 10.3892/ijo.2018.4494. Epub 2018 Jul 20.
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High expression of TRIM29(ATDC) contributes to poor prognosis and tumor metastasis by inducing epithelialmesenchymal transition in osteosarcoma.Oncol Rep. 2017 Sep;38(3):1645-1654. doi: 10.3892/or.2017.5842. Epub 2017 Jul 21.
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miR-491-3p suppresses the growth and invasion of osteosarcoma cells by targeting TSPAN1.Mol Med Rep. 2017 Oct;16(4):5568-5574. doi: 10.3892/mmr.2017.7256. Epub 2017 Aug 16.
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A Novel Fluorescence-Labeled Curcumin Conjugate: Synthesis, Evaluation and Imaging on Human Cell Lines.Curr Pharm Des. 2018;24(16):1821-1826. doi: 10.2174/1381612824666180406103317.
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The study of mechanism of miR-34c-5p targeting FLOT2 to regulate proliferation, migration and invasion of osteosarcoma cells.Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):3559-3568. doi: 10.1080/21691401.2019.1640714.
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AUF1 positively controls angiogenesis through mRNA stabilization-dependent up-regulation of HIF-1 and VEGF-A in human osteosarcoma.Oncotarget. 2019 Aug 6;10(47):4868-4879. doi: 10.18632/oncotarget.27115. eCollection 2019 Aug 6.
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Circular RNA 0001785 regulates the pathogenesis of osteosarcoma as a ceRNA by sponging miR-1200 to upregulate HOXB2.Cell Cycle. 2019 Jun;18(11):1281-1291. doi: 10.1080/15384101.2019.1618127. Epub 2019 May 22.
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The m6A methyltransferase METTL3 promotes osteosarcoma progression by regulating the m6A level of LEF1.Biochem Biophys Res Commun. 2019 Aug 27;516(3):719-725. doi: 10.1016/j.bbrc.2019.06.128. Epub 2019 Jun 26.
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MicroRNA-765 targets MTUS1 to promote the progression of osteosarcoma via mediating ERK/EMT pathway.Eur Rev Med Pharmacol Sci. 2019 Jun;23(11):4618-4628. doi: 10.26355/eurrev_201906_18040.
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Myosin-18B Promotes the Assembly of Myosin II Stacks for Maturation of Contractile Actomyosin Bundles.Curr Biol. 2019 Jan 7;29(1):81-92.e5. doi: 10.1016/j.cub.2018.11.045. Epub 2018 Dec 20.
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Circ_ORC2 enhances the regulatory effect of miR-19a on its target gene PTEN to affect osteosarcoma cell growth.Biochem Biophys Res Commun. 2019 Jul 5;514(4):1172-1178. doi: 10.1016/j.bbrc.2019.04.188. Epub 2019 May 15.
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High Expression of PQBP1 and Low Expression of PCK2 are Associated with Metastasis and Recurrence of Osteosarcoma and Unfavorable Survival Outcomes of the Patients.J Cancer. 2019 May 12;10(9):2091-2101. doi: 10.7150/jca.28480. eCollection 2019.
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Long non-coding RNA TUG1 regulates the progression and metastasis of osteosarcoma cells via miR-140-5p/PFN2 axis.Eur Rev Med Pharmacol Sci. 2019 Nov;23(22):9781-9792. doi: 10.26355/eurrev_201911_19541.
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Triggering of p73-dependent apoptosis in osteosarcoma is under the control of E2Fs-pRb2/p130 complexes.Oncogene. 2003 Jun 5;22(23):3518-29. doi: 10.1038/sj.onc.1206487.
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Extracellular vesicles from osteosarcoma cell lines contain miRNAs associated with cell adhesion and apoptosis.Gene. 2019 Aug 20;710:246-257. doi: 10.1016/j.gene.2019.06.005. Epub 2019 Jun 6.
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A Novel lncRNA MYOSLID/miR-1286/RAB13 Axis Plays a Critical Role in Osteosarcoma Progression.Cancer Manag Res. 2019 Dec 10;11:10345-10351. doi: 10.2147/CMAR.S231376. eCollection 2019.
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RRAS2 knockdown suppresses osteosarcoma progression by inactivating the MEK/ERK signaling pathway.Anticancer Drugs. 2019 Oct;30(9):933-939. doi: 10.1097/CAD.0000000000000799.
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LncRNA-SRA1 Suppresses Osteosarcoma Cell Proliferation While Promoting Cell Apoptosis.Technol Cancer Res Treat. 2019 Jan 1;18:1533033819841438. doi: 10.1177/1533033819841438.
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STAG2 loss-of-function mutation induces PD-L1 expression in U2OS cells.Ann Transl Med. 2019 Apr;7(7):127. doi: 10.21037/atm.2019.02.23.
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miR-1301/TRIAP1 Axis Participates in Epirubicin-Mediated Anti-Proliferation and Pro-Apoptosis in Osteosarcoma.Yonsei Med J. 2019 Sep;60(9):832-841. doi: 10.3349/ymj.2019.60.9.832.
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