Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMMSDOY)

Drug Name
Stiripentol Drug Info
Synonyms Diacomit; ME-2080; Stiripentol (oral); Stiripentol (oral), Laboratoires Biocodex
Indication
Disease Entry ICD 11 Status REF
Dravet syndrome 8A61.11 Approved [1]
Epilepsy 8A60-8A68 Approved [2]
Cross-matching ID
PubChem CID
5311454
ChEBI ID
CHEBI:94435
CAS Number
CAS 49763-96-4
TTD Drug ID
DMMSDOY
INTEDE Drug ID
DR1507
ACDINA Drug ID
D01440

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DME
DOT
Drug Status:
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting GABA(A) receptor gamma-3 (GABRG3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zolpidem DMWOSKJ Insomnia 7A00-7A0Z Approved [7]
Allopregnanolone DMNLHAC Depression 6A70-6A7Z approved [8]
Clobazam - Lundbeck DMW1OQ0 Anxiety disorder 6B00-6B0Z Approved [9]
Flumazenil DMPCG2L Benzodiazepine overdose PC91 Approved [7]
Thiamylal DMHDF7B Anaesthesia 9A78.6 Approved [9]
Ganaxolone DMXJMKF Epileptic seizures 8A61-8A6Z Approved [8]
Mebutamate DM0KYI4 Anxiety disorder 6B00-6B0Z Approved [9]
Metharbital DM5A38V Epilepsy 8A60-8A68 Approved [9]
Etomidate DMZI3WO Anaesthesia 9A78.6 Approved [9]
Remimazolam DMLVSYX Procedural sedation JB0C.3 Approved [10]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [11]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [12]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [13]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [14]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [15]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [16]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [17]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [18]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [12]
Verapamil DMA7PEW Angina pectoris BA40 Approved [19]
Eplerenone DMF0NQR Heart failure BD10-BD13 Approved [39]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [40]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [41]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [42]
Proguanil DMBL79I Malaria 1F40-1F45 Approved [43]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [43]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [44]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [45]
Capsaicin DMGMF6V Back pain ME84.Z Approved [46]
Axitinib DMGVH6N Renal cell carcinoma 2C90 Approved [47]
⏷ Show the Full List of 20 Drug(s)
Drug(s) Metabolized By Cytochrome P450 1A2 (CYP1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [20]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [21]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [22]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [23]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [24]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [25]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [17]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [26]
Verapamil DMA7PEW Angina pectoris BA40 Approved [27]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [28]
Zolmitriptan DM1IB4Q Migraine 8A80 Approved [53]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [53]
Etoricoxib DM6A4NW Rheumatoid arthritis FA20 Approved [53]
Capsaicin DMGMF6V Back pain ME84.Z Approved [50]
Hesperetin DMKER83 High blood cholesterol level 5C80.00 Approved [54]
Nifedipine DMSVOZT Angina pectoris BA40 Approved [55]
Zileuton DMVRIC2 Allergic asthma CA23.0 Approved [56]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [57]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [51]
Caffeine DMKBJWP Allergic rhinitis CA08.0 Approved [58]
⏷ Show the Full List of 20 Drug(s)
Drug(s) Metabolized By Mephenytoin 4-hydroxylase (CYP2C19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [29]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [30]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [31]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [32]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [33]
Verapamil DMA7PEW Angina pectoris BA40 Approved [34]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [35]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [36]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [37]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [38]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome P450 2C19 (CYP2C19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [40]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [48]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [42]
Chloramphenicol DMFXEWT Bacterial infection 1A00-1C4Z Approved [49]
Capsaicin DMGMF6V Back pain ME84.Z Approved [50]
Pentamidine DMHZJCG African trypanosomiasis 1F51 Approved [43]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [43]
Desipramine DMT2FDC Attention deficit hyperactivity disorder 6A05.Z Approved [48]
Amitriptyline DMK7F9S Depression 6A70-6A7Z Approved [51]
Clobazam - Lundbeck DMW1OQ0 Anxiety disorder 6B00-6B0Z Approved [52]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
GABA(A) receptor gamma-3 (GABRG3) TTEX6LM GBRG3_HUMAN Modulator [3]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) Main DME DE4LYSA CP3A4_HUMAN Substrate [4]
Mephenytoin 4-hydroxylase (CYP2C19) Main DME DEGTFWK CP2CJ_HUMAN Substrate [5]
Cytochrome P450 1A2 (CYP1A2) Main DME DEJGDUW CP1A2_HUMAN Substrate [6]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Cytochrome P450 1A2 (CYP1A2) OTLLBX48 CP1A2_HUMAN Gene/Protein Processing [6]
Cytochrome P450 2C19 (CYP2C19) OTFMJYYE CP2CJ_HUMAN Gene/Protein Processing [6]
Cytochrome P450 3A4 (CYP3A4) OTQGYY83 CP3A4_HUMAN Gene/Protein Processing [6]

References

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