Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMOPWSX)

Drug Name
Ibrolipim Drug Info
Synonyms Ibrolipim < Prop INN; NO-1886; OPF-009; 4-[N-(4-Bromo-2-cyanophenyl)carbamoyl]benzylphosphonic acid diethyl ester
Indication
Disease Entry ICD 11 Status REF
Hyperlipidaemia 5C80 Phase 2 [1]
Cross-matching ID
PubChem CID
131601
CAS Number
CAS 133208-93-2
TTD Drug ID
DMOPWSX

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting Lipoprotein lipase (LPL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [3]
Gemfibrozil DMD8Q3J Hyperlipidaemia 5C80 Approved [4]
AMT-011 DM8QIRN Blood forming organ disorder JB64.1 Phase 3 [5]
WS-070117 DMYNIG5 Hyperlipidaemia 5C80 Investigative [5]
Drug(s) Affected By Cocaine esterase (CES2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [6]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [7]
Dextropropoxyphene DM23HCX Pain MG30-MG3Z Approved [8]
Methotrexate DM2TEOL Anterior urethra cancer Approved [9]
Quercetin DM3NC4M Obesity 5B81 Approved [10]
Tacrine DM51FY6 Alzheimer disease 8A20 Approved [11]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [12]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [13]
Testosterone enanthate DMB6871 N. A. N. A. Approved [14]
Cantharidin DMBP5N3 Molluscum contagiosum infection 1E76 Approved [15]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Carbohydrate sulfotransferase 1 (CHST1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [13]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [17]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [18]
Arsenic DMTL2Y1 N. A. N. A. Approved [19]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [20]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [21]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [22]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [23]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [24]
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Drug(s) Affected By Cytochrome P450 1A1 (CYP1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [25]
Riluzole DMECBWN Amyotrophic lateral sclerosis 8B60.0 Approved [26]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [27]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [28]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [29]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [30]
Ethacrynic acid DM60QMR Edema MG29 Approved [31]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [32]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [33]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [34]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome P450 1A2 (CYP1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zolmitriptan DM1IB4Q Migraine 8A80 Approved [35]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [35]
Etoricoxib DM6A4NW Rheumatoid arthritis FA20 Approved [35]
Capsaicin DMGMF6V Back pain ME84.Z Approved [36]
Hesperetin DMKER83 High blood cholesterol level 5C80.00 Approved [37]
Stiripentol DMMSDOY Dravet syndrome 8A61.11 Approved [38]
Nifedipine DMSVOZT Angina pectoris BA40 Approved [39]
Zileuton DMVRIC2 Allergic asthma CA23.0 Approved [40]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [41]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [42]
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Drug(s) Affected By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Eplerenone DMF0NQR Heart failure BD10-BD13 Approved [43]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [44]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [45]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [46]
Proguanil DMBL79I Malaria 1F40-1F45 Approved [47]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [47]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [48]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [49]
Capsaicin DMGMF6V Back pain ME84.Z Approved [50]
Axitinib DMGVH6N Renal cell carcinoma 2C90 Approved [51]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Liver carboxylesterase 1 (CES1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [52]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [53]
Dextropropoxyphene DM23HCX Pain MG30-MG3Z Approved [8]
Selenium DM25CGV N. A. N. A. Approved [54]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [55]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [56]
Tacrine DM51FY6 Alzheimer disease 8A20 Approved [57]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [6]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [58]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [59]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sulfotransferase 2A1 (SULT2A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [60]
Methotrexate DM2TEOL Anterior urethra cancer Approved [9]
Quercetin DM3NC4M Obesity 5B81 Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [61]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [61]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [62]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [13]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [64]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [65]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Lipoprotein lipase (LPL) TTOF3WZ LIPL_HUMAN Modulator [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Carbohydrate sulfotransferase 1 (CHST1) OT2GRC5R CHST1_HUMAN Gene/Protein Processing [2]
Cocaine esterase (CES2) OTC647SQ EST2_HUMAN Gene/Protein Processing [2]
Cytochrome P450 1A1 (CYP1A1) OTE4EFH8 CP1A1_HUMAN Gene/Protein Processing [2]
Cytochrome P450 1A2 (CYP1A2) OTLLBX48 CP1A2_HUMAN Gene/Protein Processing [2]
Cytochrome P450 3A4 (CYP3A4) OTQGYY83 CP3A4_HUMAN Gene/Protein Processing [2]
Liver carboxylesterase 1 (CES1) OT9L0LR8 EST1_HUMAN Gene/Protein Processing [2]
Sulfotransferase 2A1 (SULT2A1) OT0ISKQ4 ST2A1_HUMAN Gene/Protein Processing [2]

References

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