General Information of Drug (ID: DMRQD04)

Drug Name
Tramadol Drug Info
Synonyms Conzip; Ryzolt; Tramadol Hydrochloride; Ultram Er; Rybix Odt; Ultram
Indication
Disease Entry ICD 11 Status REF
Pain MG30-MG3Z Approved [1] , [2]
Therapeutic Class
Analgesics
Cross-matching ID
PubChem CID
33741
ChEBI ID
CHEBI:75725
CAS Number
CAS 123154-38-1
TTD Drug ID
DMRQD04
VARIDT Drug ID
DR00088
INTEDE Drug ID
DR1627
ACDINA Drug ID
D00693

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DME
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Solid tumour/cancer 2A00-2F9Z Approved [7]
Progesterone DMUY35B Premature labour JB00 Approved [8]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [9]
Estradiol DMUNTE3 Breast cancer 2C60-2C65 Approved [10]
Acetaminophen DMUIE76 Pain MG30-MG3Z Approved [11]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [12]
Etoposide DMNH3PG Solid tumour/cancer 2A00-2F9Z Approved [13]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [14]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [8]
Verapamil DMA7PEW Hypertension BA00-BA04 Approved [15]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [16]
Estradiol DMUNTE3 Breast cancer 2C60-2C65 Approved [17]
Acetaminophen DMUIE76 Pain MG30-MG3Z Approved [18]
Etoposide DMNH3PG Solid tumour/cancer 2A00-2F9Z Approved [19]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [20]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [21]
Mycophenolate mofetil DMPQAGE Organ transplant rejection NE84 Approved [22]
Metronidazole DMTIVEN Amoebiasis 1A36 Approved [6]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [23]
Ethanol DMDRQZU Chronic pain MG30 Approved [24]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Metabolized By Cytochrome P450 2D6 (CYP2D6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Solid tumour/cancer 2A00-2F9Z Approved [25]
Progesterone DMUY35B Premature labour JB00 Approved [26]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [27]
Acetaminophen DMUIE76 Pain MG30-MG3Z Approved [11]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [15]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [28]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [29]
Dopamine DMPGUCF Parkinson disease 8A00.0 Approved [30]
Nicotine DMWX5CO Nicotine dependence 6C4A.2 Approved [31]
Propranolol DM79NTF Migraine 8A80 Approved [32]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Metabolized By Cytochrome P450 2B6 (CYP2B6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [33]
Verapamil DMA7PEW Hypertension BA00-BA04 Approved [34]
Diclofenac DMPIHLS Osteoarthritis FA00-FA05 Approved [35]
Estrone DM5T6US Menopausal and postmenopausal disorder GA30 Approved [36]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [37]
Irinotecan DMP6SC2 Colorectal cancer 2B91.Z Approved [38]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [39]
Nicotine DMWX5CO Nicotine dependence 6C4A.2 Approved [40]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [41]
Amitriptyline DMK7F9S Depression 6A70-6A7Z Approved [42]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Transported By P-glycoprotein 1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Bacterial infection 1A00-1C4Z Approved [43]
Doxorubicin DMVP5YE Solid tumour/cancer 2A00-2F9Z Approved [44]
Methotrexate DM2TEOL leukaemia 2A60-2B33 Approved [45]
Folic acid DMEMBJC Folate-deficiency anemia 3A02.Y Approved [46]
Fluorouracil DMUM7HZ Solid tumour/cancer 2A00-2F9Z Approved [45]
Cisplatin DMRHGI9 Solid tumour/cancer 2A00-2F9Z Approved [45]
Progesterone DMUY35B Premature labour JB00 Approved [47]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [45]
Estradiol DMUNTE3 Breast cancer 2C60-2C65 Approved [48]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [49]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Targeting 5-HT 2C receptor (HTR2C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Metergolin DMJFP6G Hyperprolactinaemia 5A60.1 Approved [50]
Lorcaserin DMG6OYJ Obesity 5B81 Approved [51]
Mirtazapine DML53ZJ Depression 6A70-6A7Z Approved [52]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [53]
Methysergide DM1EF73 Migraine 8A80 Approved [54]
Eltoprazine DMW6C81 Attention deficit hyperactivity disorder 6A05.Z Phase 3 [55]
M100907 DM7ZFBA Sleep-wake disorder 7A00-7B2Z Phase 3 [56]
SR46349B DM1ODMR Primary insomnia 7A00 Phase 3 [57]
Vabicaserin DM9GZW6 Psychotic disorder 6A20-6A25 Phase 2 [58]
Nuplazid DMOJA5G Alzheimer disease 8A20 Phase 2 [59]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
5-HT 2C receptor (HTR2C) TTWJBZ5 5HT2C_HUMAN Modulator [3]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [4]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Substrate [5]
Cytochrome P450 2D6 (CYP2D6) Main DME DECB0K3 CP2D6_HUMAN Substrate [5]
UDP-glucuronosyltransferase 1A1 (UGT1A1) DEYGVN4 UD11_HUMAN Substrate [6]
Cytochrome P450 2B6 (CYP2B6) DEPKLMQ CP2B6_HUMAN Substrate [5]

References

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